OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11759543	Although the cytotoxicity of vorinostat differs between 5637 and BFTC 905, the combined effect of doxorubicin and vorinostat is similar in both cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC9429973	One patient with PR on day 28 achieved a CR after a year of follow-up.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "patient", "with", "PR", "on", "day", "28", "ac...
PMC11468365	Ultimately, 934 genes are selected to represent the final cell line vector, which is then normalized by the tanh-norm method.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ultimately", ...
PMC11615743	However, CEM cells displayed more significant fluorescence enhancement, with a signal gain of 90 (Figure 2B,C).	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However",...
PMC10759659	The effects of ARID1A deficiency on HCC proliferation were assessed by using a Cell Counting Kit-8 (CCK-8) (HY-K0301; MedChemExpress) and clone formation assays.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11225860	Dmytro Kovalskyy: Visualization, Software.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Dmytro", "Kovalskyy", ":", "Visualization", ",", "Software", "." ] } ]
PMC6835428	Not only is FAK involved in the regulation of OC cell migration, invasion, adhesion, proliferation, and survival, it has recently been discovered that it promotes PTX resistance in OC as well as in other cancers .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8728081	The DTA-TGA (Perkin Elmer, USA) experiment was conducted in an air atmosphere.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "DTA-TGA", "(", "Perkin", "Elmer", ",", "USA", ...
PMC11665555	Here, we report a gemcitabine resistance mechanism that promotes cancer reprogramming via the metabolic enzyme OXCT1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Here", ",", "we", "report", "a", "gemcitabi...
PMC11684821	Killing by MC.27.759S ranged between 96.1% and 98.9% for A549, FM72, FM74, RD-ES, and K-562 cell lines, and, for MC.7.G5, killing was between 95% and 98.4% for cell lines A549, FM72, FM74, ES-5838, RD-ES, and MDA-MB-231 (Figure 2A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", ...
PMC11792090	Representative flow cytometric profiles of CD47 and CAR expression on CD47 UCAR-T cells. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Representative", "flow", "cytometric", "profiles", "of", "CD47", "and"...
PMC11731161	The above results clearly indicate that SEL reduces XPO1 protein levels by promoting its ubiquitination and degradation, which is crucial for the functional inhibition of XPO1 by SEL.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11224020	Remarkably, we found that Arpin-knockout (Arpin) immature DCs displayed an increased sensitivity to cell shape changes as they upregulated Ccr7 when confined at a height of 4 µm instead of 3 µm (Fig. 3g) in a cPLA2-dependent manner (Fig. 3h).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	NAbs ≥30% were detected in 14/27 patients, 11 of whom (84%) had already increased complement activation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "NAbs", "≥30", "%"...
PMC11786767	A: Experimental flowchart.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "A", ":", "Experimental", "flowchart", "." ] } ]
PMC10808409	This is because TPGS has been reported to act as a selective potent proapoptotic agent for cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "is", "because", "TPGS", "has",...
PMC11354225	In addition, in this study, an interesting finding was related to clonogenic capability.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", "in", "this", "study", ",", "an...
PMC11551844	After 24–48 h, solutions were then subjected to dialysis (12–14 kDa dialysis) in distilled water for 2–3 days at room temperature.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11686380	The induced protein instability was observed in neuronal cells but not in COS7 cells, indicating that it was not intrinsic to the protein structure but context-dependent.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9352806	In addition, commercial databases including KEGG (http://www.genome.jp/kegg/) and MetaboAnalyst (http://www.metaboanalyst.ca/) were used for pathway enrichment analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ...
PMC9429973	This was increased by 50μg every 2 weeks until patients had achieved complete hematological response (CHR): hematocrit <45% without phlebotomy in the preceding 3M, platelets ≤400×10/L, leukocytes ≤10×10 /L, or reached the maximum recommended single dose (500μg).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8193046	The ABCC1-overexpressing H69AR cells were provided by American Type Culture Collection (ATCC CRL-11351), which were cultured with RPMI-1640 medium to which FCS (20%), streptomycin (50 µg/µL), penicillin G (50 U/mL), as well as L-glutamine (2 mM) were added.	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Here we propose primers for measuring ABL1 control gene expression allowing reliable calculation of chimeric transcripts relative expression, regardless of RNA sample purity, in contrast to primers recommended by the EAC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11607638	After emergence, SKR expression increased significantly.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "emergence", ",", "SKR", "expression", "increased", "significantly", "." ] } ]
PMC9780037	This bond is cleaved under reductive environment and cyt c is released (Figure 3D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "bond", "is", "cleaved", "under", "reductive", ...
PMC6901583	a GIST882 and GIST-T1 cells stably expressing vector or BRD4 were harvested, and expression of the indicated proteins was examined by Western blotting.	[ { "tags": [ "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], ...
PMC9000591	After that, the methanolic extracts were combined and filtered through filter papers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "that", ",", "the", "methanolic", "extracts", "were", "combined", ...
PMC9429973	Methods: The BYOND trial included 163 patients with CML resistant or intolerant to prior TKIs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Methods", ":", "The", "BYOND", "trial", "included", ...
PMC11773391	Taken together, most studies have proven that the main resistance of tumour cells to TMZ is the expression level of MGMT.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Taken", "tog...
PMC11752740	In certain cancers, proteins vital for inducing cancer cell death can be rapidly inactivated and eliminated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "certain", "cancers", ",", "proteins", ...
PMC10123657	The reduced sensitivity to chemotherapeutic drugs and oxidative stress of leukemic cells co-cultured with stromal cells has been reported previously .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "reduced", "sensitivit...
PMC9105697	A total of 10 ng input of cfDNA was used and adapters were ligated to attach unique molecular identifiers (UMI) to each side of the DNA fragment with single indices.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10936243	When the cat is stable, everything will be put in place accordingly.”	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "When", "the", "cat", "is", "stable", ",", "everything", "will", ...
PMC6379402	We assess the quality of the fit between the data and the network model by the overlap between two distributions: the distribution of GCD-11 distances between the data and the model networks and the distribution of GCD-11 distances between model networks.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11064533	It was reported that overall motility and fimbriae genes are downregulated in the transcriptome when E. coli adhere to host cells and form biofilms (43, 44).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11568601	B TGT increased the apoptosis rate of osteosarcoma cells according to the flow cytometry assay.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "B", "TGT", "increased", "the", "apoptosis", "rate", "of", ...
PMC11607638	Sulfakinin receptor expressed ectopically in mammalian cells CHO‐K1 responds to sulfakinin stimulation with persistent calcium spikes, blockable with receptor antagonist.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Sulfakinin", "...
PMC11477621	Two series of target compounds were designed and prepared.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Two", "series", "of", "target", "compounds", "were", "designed", "and", "prepared", "." ] } ]
PMC9164404	Due to the importance of Pt(II)-based drugs in cancer therapy, Pt(IV) drugs and their DDS are very promising.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Due", "to", "the", "im...
PMC6901583	The assay for wound healing involved six-well plates used for seeding GIST cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "assay", "for", "wound", "healing", "involved", "six-well", "plates",...
PMC11224020	Consistent with these results, we further found that DCs lacking Wiscott–Aldrich syndrome protein (WASp; encoded by the gene Was), which was recently shown to activate ARP2/3 in the DC perinuclear area, behaved similar to cells treated with CK666; they did not upregulate CCR7 expression nor show cPLA2 nuclear transloca...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11463018	m.p.:	[ { "tags": [ "O", "O", "O" ], "tokens": [ "m.p", ".", ":" ] } ]
PMC11515150	Previous research showed BCMA CAR expression of PB-derived NK cells was 38.4% and VHH directed BCMA CAR-NK cells exhibited remarkable specific killing ability .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	We evaluated EASIX-1year in 102 (53 males) patients who were alive after 1 year without relapse.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "evaluated", "EASIX-1year", "in", ...
PMC9910796	Immunogold labeling of zippers with antibodies to pp62 (D) and pp220 (F) followed by protein A-gold (10 nm). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9545474	Complexes were dissolved in either DMSO (complexes 4, 5, and 8) or PBS (complexes 6 and 7) to provide stock solutions which were further diluted with media to provide a range of final concentrations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11574271	Studies from in vivo models demonstrate that increased RON expression facilitates tumor growth and metastasis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Studies", "from", "in", "vivo", "models", "demonstrate", "t...
PMC11738017	Without GSI treatment at an E:T ratio of 3:1, the OPM2_BCMA cells displayed increased resistance to anti-BCMA TCE when compared with OPM2 cells, despite their elevated surface BCMA expression (Figure 3H, right panel).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", ...
PMC4485786	Cytokine-induced elongated, multinucleate, and syncytial morphology in A204 cells (middle and right) compared to A204 cells in standard culture (left), imaged by transmission microscopy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "...
PMC10958426	Shaded areas corresponded to 0.95 confidence interval. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Shaded", "areas", "corresponded", "to", "0.95", "confidence", "interval", ".", "(" ] } ]
PMC11740207	NDSCs are SCs derived from nodes and ducts within the body, primarily associated with hematopoietic and neural systems (Lee et al., 2014).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10705095	Fluorescence intensity was measured as the ratio of fluorescence at 530 nm to that at 485 nm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fluorescence", "intensity", "was", "measured", "a...
PMC11718109	A non-overlapping localization of VMAT2 and VGLUT2 is in fact supported by previous studies of axons of DA neurons in the ventral striatum and primary cultures of DA neurons.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11695623	The expression of DCUN1D5 in HBE and H1299. (	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O" ], "tokens": [ "The", "expression", "of", "DCUN1D5", "in", "HBE", "and", "H1299", ".", "(" ] } ]
PMC11590005	The high percentage of white dental students in the study population stands out and shows that dental education in Brazil is still an environment for white students .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11377827	Endogenous 14-3-3 was immunoprecipitated and immunoblotted for USP43 and HIF-1α (D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Endogenous", "14", "-", "3", "-", "3", ...
PMC11742047	Due to their oxidation, membrane permeability increases, causing the release of important proteins, including cytochrome c. On the other hand, CL provides the essential activating platform for caspase 8 on mitochondria.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10723784	CBD induced a synergistic effect when it was combined with bortezomib, a protease inhibitor, on multiple myeloma cells and also in breast cancer. ,	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9031474	For the Wittig derivative 64 and HWE derivative 73, increased concentrations of c-PARP1 and γH2AX were observed after exposure to cancer cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", ...
PMC11075223	C. dahurica extract also embodied significant inhibitory effect on the MCF-7 cells proliferation based on the BrdU-proliferation test .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "C.", "dahurica", "extract", "also",...
PMC11258145	The course of surface pressure isotherms of monolayers of DPPC and DOPC containing curcumin clearly indicates that this compound is incorporated into monolayers, locating between lipid molecules.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11266100	Dashed line indicates average transfection efficacy using 1.2 kV/cm × 100 μs × 8 protocol and electroporation buffer No.1, which serves as a positive control.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10998613	The signals were recorded using two channel time-correlated single-photon counting modules (PicoHarp 300, PicoQuant).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "signals", "were", "recorded", "using", ...
PMC9429973	The treatment was conducted according to the AML-BFM study 2004 and 2012 as well as the register 12 and 17.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "treatment", "was", ...
PMC10197932	It would be interesting to clarify what other mechanisms could occur for the survival of healthy lymphocytes upon US-treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "would", "be", "interesting"...
PMC9429973	For nursing managers, it is essential to optimize the allocation of human resources further and provide necessary infection protection equipment to reduce the risk of hospital-acquired infection caused by the serious pollution of nurses’ work clothes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	L. Hasan Bou Issa, L. Fléchon, W. Laine, A. Ouelkdite, G. Escure, S. Gaggero, T. Ingegnere, R. Sklavenitis Pistofidis, I. M. Ghobrial, T. Facon, S. Mitra, J. Kluza, B. Quesnel, S. Manier Univ Lille, Canther, INSERM UMR-S1277 - CNRS UMR9020; CHU Lille, Department of Hematology, Lille, France; Dana-Farber Cancer Institut...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	A clinical decision tree model was generated by recursive partitioning and minimizing cross-validation error, which outperformed other tested models (e.g elastic net and LASSO regression) in accuracy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11694625	In the experiment, 6-well plates were used to culture MCF-7 cells to investigate the effect of 3b or 3c on the production of reactive oxygen species in cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11190062	Cells were lysed in lysis buffer containing 50 mM Tris–HCl, 1% NP40, 150 mM NaCl, 10% glycerol, 1 mM Na3VO4, 50 mM NaF, and cOmplete Protease Inhibitor (Roche Diagnostics, Mannheim, Germany).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Secondary ITP was classified when one or more associated diagnoses were registered any time before or up to 30 days after ITP diagnosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Seconda...
PMC3995603	Treatment with AC suppressed both the production of NO in LPS-stimulated RAW264.7 cells and the production of histamine in PMA/A23187-stimulated MC/9 mast cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens"...
PMC9672323	The effect of dexamethasone and piroxicam was measured on the cell cycle phase of T cells in non-treated PBMCs, PBMCs treated with 30 μM piroxicam or with 1 μM dexamethasone (n = 3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6650823	Highlighted by Josef Jampilek Despite the approval of many anti-proliferative/anticancer drugs, cancer remains the second leading cause of death worldwide.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Highlighted", "by", ...
PMC9429973	Herein we provide survival outcomes on the first randomized trial in newly diagnosed HRMM, S1211, to follow-up on the previously reported progression-free survival (PFS) (NCT01668719, Usmani SZ et al, Lancet Haem 2021).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Among patients achieving CR/CRi, 60% attained minimal residual disease negativity by flow cytometry.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Among", "patients", "achieving", "CR/CRi", ",", "60", "%", ...
PMC2118063	Notably, bands were observed only with anti-IRF8–precipitated DNA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notably", ",", "bands", "were", "observed", "only", "with", "anti-IRF8–precipitated", "DNA", "." ] } ...
PMC9429973	Lenalidomide was used in 1L therapy among 8.5% pts in US/CAN and 5.8% in UK/EU.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lenalidomide", "was", "used", "in", "1L", "...
PMC11746948	In 2-BP-stimulated cancer cells that were treated with RSL3 alone or alongside various cell death inhibitors, RSL3-induced cell death could be fully reversed by Fer-1 but not the apoptosis inhibitor z-VDA-fmk, the necrosis inhibitor Necrostatin-1, and the autophagy inhibitor Bafilomycin A1 (BafA1) (Fig. 1h).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9985266	Fig. 5IL-27 upregulates MEG3 expression by inhibiting DNMT1-mediated methylation of the MEG3 promoter.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "5IL-27", "upregulates", "MEG3", "expression", "by", "inhibiting", "...
PMC11754291	Scale bars = 400 µm.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bars", "=", "400", "µm", "." ] } ]
PMC6643347	Studies of the major target cells involved in HIV pathogenesis (such as peripheral blood mononuclear cells, macrophages, and dendritic cells) constitute an invariable component of the current requirements that need to be met in designing the assessment of new antivirals.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11742431	Western‐blot analysis indicated that 5637 had the lowest total PD‐L1 expression level in the four bladder cell lines (Figure 2C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Western‐blot", ...
PMC11119602	The data obtained in this study showed that TG2-L appears to be cytoplasmically distributed in the cell, whereas most of the TG2-S appears to be associated with subcellular membranous structures.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11574029	Subsequently, the NICD translocates to the nucleus, where it binds to CSL elements in the promoters of certain genes, initiating the transcription of downstream target genes .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11012012	This resulted in the suppression of T cell responses and activity in vitro and in vivo.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "resulted", "in", "the", "suppression", "of", ...
PMC11621493	However, slightly increased activity was observed using 2-oleoyl MAG as substrate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "slightly", "increased", "activity", "was", "observed", "using", ...
PMC9429973	At the time they received plasma, 25% of the patients (15) were anticoagulated and half of them were D-dimer positive.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC7369657	Western blotting was used to measure the expression of apoptosis-related proteins (Bax, Bcl-2, cytochrome-C, caspase-3, cleaved-caspase-3, PARP1, and cleaved-PARP1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11502443	IP1 concentrations were determined from a standard curve generated in duplicate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "IP1", "concentrations", "were", "determined", "from", "a", "standard", "curve", "generated"...
PMC10212663	Consistently, the expression of RANKL was significantly higher in KRAS‐mt LUAD than in KRAS‐wt ones both in advanced and non‐advanced settings.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Consistently", ...
PMC11742431	By comparing PROTABs, GlueTACs, and BumPeD, it can be found that BumPeD combines the advantages of PROTABs and GlueTACs, not only by combining bispecific nanobodies with PROTACs but also by introducing the concept of the tumor microenvironment to enhance the specificity of the target of degradation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11583690	This is probably because of the higher DTX release by BPMO@DTX when compared with MSN@DTX in the experimental conditions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "is", "probably", "because...
PMC11806106	With these kinds of sensors, it is also possible to analyze the real velocity of agonist-induced conformational changes within the receptor.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "With", "thes...
PMC9429973	However, recent evidence suggests that the extent of macrophage contribution to stress erythropoiesis is likely to be both tissue- and stress-type dependent.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However...
PMC11457557	Consequently, the precision medicine strategy of adapting treatment to the features of each patient has been effectively applied to monogenic DM subtypes, Maturity-onset diabetes of the young, and neonatal DM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: We investigated SETD2/H3K36me3 status in CD34+ progenitors of CP CML pts and whether SETD2/H3K36me3 deficiency may play a role in genomic instability in CML models.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11628309	This reduction can lead to cell death activation, as it allows the release of apoptotic factors that are typically inhibited by 14-3-3 proteins (Yacoubian et al., 2010).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11066331	For mass spectrometry, the MALDI 7090 TOF-TOF instrument (Shimadzu Kratos Analytical) equipped with the 2 kHz ultra-fast solid-state UV laser (Nd-YAG: 355 nm) was used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10823017	ICA-1 was used as an inhibitor of PKC-ι.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ICA-1", "was", "used", "as", "an", "inhibitor", "of", "PKC-ι", "." ] } ]

PMC11759543

Although the cytotoxicity of vorinostat differs between 5637 and BFTC 905, the combined effect of doxorubicin and vorinostat is similar in both cell lines.

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PMC9429973

One patient with PR on day 28 achieved a CR after a year of follow-up.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "patient", "with", "PR", "on", "day", "28", "ac...

PMC11468365

Ultimately, 934 genes are selected to represent the final cell line vector, which is then normalized by the tanh-norm method.

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PMC11615743

However, CEM cells displayed more significant fluorescence enhancement, with a signal gain of 90 (Figure 2B,C).

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PMC10759659

The effects of ARID1A deficiency on HCC proliferation were assessed by using a Cell Counting Kit-8 (CCK-8) (HY-K0301; MedChemExpress) and clone formation assays.

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PMC11225860

Dmytro Kovalskyy: Visualization, Software.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Dmytro", "Kovalskyy", ":", "Visualization", ",", "Software", "." ] } ]

PMC6835428

Not only is FAK involved in the regulation of OC cell migration, invasion, adhesion, proliferation, and survival, it has recently been discovered that it promotes PTX resistance in OC as well as in other cancers .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8728081

The DTA-TGA (Perkin Elmer, USA) experiment was conducted in an air atmosphere.

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PMC11665555

Here, we report a gemcitabine resistance mechanism that promotes cancer reprogramming via the metabolic enzyme OXCT1.

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PMC11684821

Killing by MC.27.759S ranged between 96.1% and 98.9% for A549, FM72, FM74, RD-ES, and K-562 cell lines, and, for MC.7.G5, killing was between 95% and 98.4% for cell lines A549, FM72, FM74, ES-5838, RD-ES, and MDA-MB-231 (Figure 2A).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", ...

PMC11792090

Representative flow cytometric profiles of CD47 and CAR expression on CD47 UCAR-T cells. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Representative", "flow", "cytometric", "profiles", "of", "CD47", "and"...

PMC11731161

The above results clearly indicate that SEL reduces XPO1 protein levels by promoting its ubiquitination and degradation, which is crucial for the functional inhibition of XPO1 by SEL.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11224020

Remarkably, we found that Arpin-knockout (Arpin) immature DCs displayed an increased sensitivity to cell shape changes as they upregulated Ccr7 when confined at a height of 4 µm instead of 3 µm (Fig. 3g) in a cPLA2-dependent manner (Fig. 3h).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

NAbs ≥30% were detected in 14/27 patients, 11 of whom (84%) had already increased complement activation.

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PMC11786767

A: Experimental flowchart.

[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "A", ":", "Experimental", "flowchart", "." ] } ]

PMC10808409

This is because TPGS has been reported to act as a selective potent proapoptotic agent for cancer cells.

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PMC11354225

In addition, in this study, an interesting finding was related to clonogenic capability.

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PMC11551844

After 24–48 h, solutions were then subjected to dialysis (12–14 kDa dialysis) in distilled water for 2–3 days at room temperature.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11686380

The induced protein instability was observed in neuronal cells but not in COS7 cells, indicating that it was not intrinsic to the protein structure but context-dependent.

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PMC9352806

In addition, commercial databases including KEGG (http://www.genome.jp/kegg/) and MetaboAnalyst (http://www.metaboanalyst.ca/) were used for pathway enrichment analysis.

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PMC9429973

This was increased by 50μg every 2 weeks until patients had achieved complete hematological response (CHR): hematocrit <45% without phlebotomy in the preceding 3M, platelets ≤400×10/L, leukocytes ≤10×10 /L, or reached the maximum recommended single dose (500μg).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8193046

The ABCC1-overexpressing H69AR cells were provided by American Type Culture Collection (ATCC CRL-11351), which were cultured with RPMI-1640 medium to which FCS (20%), streptomycin (50 µg/µL), penicillin G (50 U/mL), as well as L-glutamine (2 mM) were added.

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PMC9429973

Here we propose primers for measuring ABL1 control gene expression allowing reliable calculation of chimeric transcripts relative expression, regardless of RNA sample purity, in contrast to primers recommended by the EAC.

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PMC11607638

After emergence, SKR expression increased significantly.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "emergence", ",", "SKR", "expression", "increased", "significantly", "." ] } ]

PMC9780037

This bond is cleaved under reductive environment and cyt c is released (Figure 3D).

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PMC6901583

a GIST882 and GIST-T1 cells stably expressing vector or BRD4 were harvested, and expression of the indicated proteins was examined by Western blotting.

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PMC9000591

After that, the methanolic extracts were combined and filtered through filter papers.

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PMC9429973

Methods: The BYOND trial included 163 patients with CML resistant or intolerant to prior TKIs.

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PMC11773391

Taken together, most studies have proven that the main resistance of tumour cells to TMZ is the expression level of MGMT.

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PMC11752740

In certain cancers, proteins vital for inducing cancer cell death can be rapidly inactivated and eliminated.

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PMC10123657

The reduced sensitivity to chemotherapeutic drugs and oxidative stress of leukemic cells co-cultured with stromal cells has been reported previously .

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PMC9105697

A total of 10 ng input of cfDNA was used and adapters were ligated to attach unique molecular identifiers (UMI) to each side of the DNA fragment with single indices.

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PMC10936243

When the cat is stable, everything will be put in place accordingly.”

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PMC6379402

We assess the quality of the fit between the data and the network model by the overlap between two distributions: the distribution of GCD-11 distances between the data and the model networks and the distribution of GCD-11 distances between model networks.

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PMC11064533

It was reported that overall motility and fimbriae genes are downregulated in the transcriptome when E. coli adhere to host cells and form biofilms (43, 44).

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PMC11568601

B TGT increased the apoptosis rate of osteosarcoma cells according to the flow cytometry assay.

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PMC11607638

Sulfakinin receptor expressed ectopically in mammalian cells CHO‐K1 responds to sulfakinin stimulation with persistent calcium spikes, blockable with receptor antagonist.

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PMC11477621

Two series of target compounds were designed and prepared.

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PMC9164404

Due to the importance of Pt(II)-based drugs in cancer therapy, Pt(IV) drugs and their DDS are very promising.

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PMC6901583

The assay for wound healing involved six-well plates used for seeding GIST cells.

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PMC11224020

Consistent with these results, we further found that DCs lacking Wiscott–Aldrich syndrome protein (WASp; encoded by the gene Was), which was recently shown to activate ARP2/3 in the DC perinuclear area, behaved similar to cells treated with CK666; they did not upregulate CCR7 expression nor show cPLA2 nuclear transloca...

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PMC11463018

m.p.:

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PMC11515150

Previous research showed BCMA CAR expression of PB-derived NK cells was 38.4% and VHH directed BCMA CAR-NK cells exhibited remarkable specific killing ability .

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PMC9429973

We evaluated EASIX-1year in 102 (53 males) patients who were alive after 1 year without relapse.

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PMC9910796

Immunogold labeling of zippers with antibodies to pp62 (D) and pp220 (F) followed by protein A-gold (10 nm). (

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PMC9545474

Complexes were dissolved in either DMSO (complexes 4, 5, and 8) or PBS (complexes 6 and 7) to provide stock solutions which were further diluted with media to provide a range of final concentrations.

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PMC11574271

Studies from in vivo models demonstrate that increased RON expression facilitates tumor growth and metastasis.

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PMC11738017

Without GSI treatment at an E:T ratio of 3:1, the OPM2_BCMA cells displayed increased resistance to anti-BCMA TCE when compared with OPM2 cells, despite their elevated surface BCMA expression (Figure 3H, right panel).

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PMC4485786

Cytokine-induced elongated, multinucleate, and syncytial morphology in A204 cells (middle and right) compared to A204 cells in standard culture (left), imaged by transmission microscopy.

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PMC10958426

Shaded areas corresponded to 0.95 confidence interval. (

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PMC11740207

NDSCs are SCs derived from nodes and ducts within the body, primarily associated with hematopoietic and neural systems (Lee et al., 2014).

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PMC10705095

Fluorescence intensity was measured as the ratio of fluorescence at 530 nm to that at 485 nm.

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PMC11718109

A non-overlapping localization of VMAT2 and VGLUT2 is in fact supported by previous studies of axons of DA neurons in the ventral striatum and primary cultures of DA neurons.

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PMC11695623

The expression of DCUN1D5 in HBE and H1299. (

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PMC11590005

The high percentage of white dental students in the study population stands out and shows that dental education in Brazil is still an environment for white students .

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PMC11377827

Endogenous 14-3-3 was immunoprecipitated and immunoblotted for USP43 and HIF-1α (D).

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PMC11742047

Due to their oxidation, membrane permeability increases, causing the release of important proteins, including cytochrome c. On the other hand, CL provides the essential activating platform for caspase 8 on mitochondria.

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PMC10723784

CBD induced a synergistic effect when it was combined with bortezomib, a protease inhibitor, on multiple myeloma cells and also in breast cancer. ,

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PMC9031474

For the Wittig derivative 64 and HWE derivative 73, increased concentrations of c-PARP1 and γH2AX were observed after exposure to cancer cells .

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PMC11075223

C. dahurica extract also embodied significant inhibitory effect on the MCF-7 cells proliferation based on the BrdU-proliferation test .

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PMC11258145

The course of surface pressure isotherms of monolayers of DPPC and DOPC containing curcumin clearly indicates that this compound is incorporated into monolayers, locating between lipid molecules.

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PMC11266100

Dashed line indicates average transfection efficacy using 1.2 kV/cm × 100 μs × 8 protocol and electroporation buffer No.1, which serves as a positive control.

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PMC10998613

The signals were recorded using two channel time-correlated single-photon counting modules (PicoHarp 300, PicoQuant).

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PMC9429973

The treatment was conducted according to the AML-BFM study 2004 and 2012 as well as the register 12 and 17.

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PMC10197932

It would be interesting to clarify what other mechanisms could occur for the survival of healthy lymphocytes upon US-treatment.

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PMC9429973

For nursing managers, it is essential to optimize the allocation of human resources further and provide necessary infection protection equipment to reduce the risk of hospital-acquired infection caused by the serious pollution of nurses’ work clothes.

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PMC9429973

L. Hasan Bou Issa, L. Fléchon, W. Laine, A. Ouelkdite, G. Escure, S. Gaggero, T. Ingegnere, R. Sklavenitis Pistofidis, I. M. Ghobrial, T. Facon, S. Mitra, J. Kluza, B. Quesnel, S. Manier Univ Lille, Canther, INSERM UMR-S1277 - CNRS UMR9020; CHU Lille, Department of Hematology, Lille, France; Dana-Farber Cancer Institut...

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PMC9429973

A clinical decision tree model was generated by recursive partitioning and minimizing cross-validation error, which outperformed other tested models (e.g elastic net and LASSO regression) in accuracy.

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PMC11694625

In the experiment, 6-well plates were used to culture MCF-7 cells to investigate the effect of 3b or 3c on the production of reactive oxygen species in cells.

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PMC11190062

Cells were lysed in lysis buffer containing 50 mM Tris–HCl, 1% NP40, 150 mM NaCl, 10% glycerol, 1 mM Na3VO4, 50 mM NaF, and cOmplete Protease Inhibitor (Roche Diagnostics, Mannheim, Germany).

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PMC9429973

Secondary ITP was classified when one or more associated diagnoses were registered any time before or up to 30 days after ITP diagnosis.

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PMC3995603

Treatment with AC suppressed both the production of NO in LPS-stimulated RAW264.7 cells and the production of histamine in PMA/A23187-stimulated MC/9 mast cells.

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PMC9672323

The effect of dexamethasone and piroxicam was measured on the cell cycle phase of T cells in non-treated PBMCs, PBMCs treated with 30 μM piroxicam or with 1 μM dexamethasone (n = 3).

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PMC6650823

Highlighted by Josef Jampilek Despite the approval of many anti-proliferative/anticancer drugs, cancer remains the second leading cause of death worldwide.

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PMC9429973

Herein we provide survival outcomes on the first randomized trial in newly diagnosed HRMM, S1211, to follow-up on the previously reported progression-free survival (PFS) (NCT01668719, Usmani SZ et al, Lancet Haem 2021).

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PMC9429973

Among patients achieving CR/CRi, 60% attained minimal residual disease negativity by flow cytometry.

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PMC2118063

Notably, bands were observed only with anti-IRF8–precipitated DNA.

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PMC9429973

Lenalidomide was used in 1L therapy among 8.5% pts in US/CAN and 5.8% in UK/EU.

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PMC11746948

In 2-BP-stimulated cancer cells that were treated with RSL3 alone or alongside various cell death inhibitors, RSL3-induced cell death could be fully reversed by Fer-1 but not the apoptosis inhibitor z-VDA-fmk, the necrosis inhibitor Necrostatin-1, and the autophagy inhibitor Bafilomycin A1 (BafA1) (Fig. 1h).

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PMC9985266

Fig. 5IL-27 upregulates MEG3 expression by inhibiting DNMT1-mediated methylation of the MEG3 promoter.

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PMC11754291

Scale bars = 400 µm.

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PMC6643347

Studies of the major target cells involved in HIV pathogenesis (such as peripheral blood mononuclear cells, macrophages, and dendritic cells) constitute an invariable component of the current requirements that need to be met in designing the assessment of new antivirals.

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PMC11742431

Western‐blot analysis indicated that 5637 had the lowest total PD‐L1 expression level in the four bladder cell lines (Figure 2C).

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PMC11119602

The data obtained in this study showed that TG2-L appears to be cytoplasmically distributed in the cell, whereas most of the TG2-S appears to be associated with subcellular membranous structures.

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PMC11574029

Subsequently, the NICD translocates to the nucleus, where it binds to CSL elements in the promoters of certain genes, initiating the transcription of downstream target genes .

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PMC11012012

This resulted in the suppression of T cell responses and activity in vitro and in vivo.

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PMC11621493

However, slightly increased activity was observed using 2-oleoyl MAG as substrate.

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PMC9429973

At the time they received plasma, 25% of the patients (15) were anticoagulated and half of them were D-dimer positive.

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PMC7369657

Western blotting was used to measure the expression of apoptosis-related proteins (Bax, Bcl-2, cytochrome-C, caspase-3, cleaved-caspase-3, PARP1, and cleaved-PARP1).

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PMC11502443

IP1 concentrations were determined from a standard curve generated in duplicate.

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PMC10212663

Consistently, the expression of RANKL was significantly higher in KRAS‐mt LUAD than in KRAS‐wt ones both in advanced and non‐advanced settings.

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PMC11742431

By comparing PROTABs, GlueTACs, and BumPeD, it can be found that BumPeD combines the advantages of PROTABs and GlueTACs, not only by combining bispecific nanobodies with PROTACs but also by introducing the concept of the tumor microenvironment to enhance the specificity of the target of degradation.

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PMC11583690

This is probably because of the higher DTX release by BPMO@DTX when compared with MSN@DTX in the experimental conditions.

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PMC11806106

With these kinds of sensors, it is also possible to analyze the real velocity of agonist-induced conformational changes within the receptor.

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PMC9429973

However, recent evidence suggests that the extent of macrophage contribution to stress erythropoiesis is likely to be both tissue- and stress-type dependent.

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PMC11457557

Consequently, the precision medicine strategy of adapting treatment to the features of each patient has been effectively applied to monogenic DM subtypes, Maturity-onset diabetes of the young, and neonatal DM.

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PMC9429973

Aims: We investigated SETD2/H3K36me3 status in CD34+ progenitors of CP CML pts and whether SETD2/H3K36me3 deficiency may play a role in genomic instability in CML models.

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PMC11628309

This reduction can lead to cell death activation, as it allows the release of apoptotic factors that are typically inhibited by 14-3-3 proteins (Yacoubian et al., 2010).

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PMC11066331

For mass spectrometry, the MALDI 7090 TOF-TOF instrument (Shimadzu Kratos Analytical) equipped with the 2 kHz ultra-fast solid-state UV laser (Nd-YAG: 355 nm) was used.

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PMC10823017

ICA-1 was used as an inhibitor of PKC-ι.

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