OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11512230	This time, we have used AltMV SP to target Ewing sarcoma (ES) cells, thus expanding the number of SP for anticancer therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11252033	mRNA was quantified with the ΔΔCt method.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "mRNA", "was", "quantified", "with", "the", "ΔΔCt", "method", "." ] } ]
PMC8427838	Scale bar, 50 µM. The graph is a representative of filopodia formation (based on the localization of moesin-GFP) in RKO cells expressing moesin-GFP (MSN-GFP) alone or co-expressing MSN-GFP with TMIGD1. **	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", ...
PMC11342785	To facilitate the comparison of expression-matched cells, after 3 days, these cells were sorted on an FACSAria cell sorter (BD Biosciences) based on fluorescent protein expression levels for further analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11770746	The platinum content of each sample was measured by ICP-MS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "platinum", "content", "of", "each", "sample", "was", "measured", "by", "ICP-MS", "....
PMC10222971	Cells with damaged membranes are stained, while live cells with intact cell membranes are excluded and do not take up dye; however, this technique has two issues, and the results should be interpreted with caution.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11188874	The catalytic properties of proteasome subtypes are determined by their catalytic subunit composition.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "catalytic", "properties", "of", "proteasome", "subtypes", "are", "de...
PMC11777207	Having previously established that deletion of CD80 and external ligation of PD-L1 with the αPD-L1 10F9.G2 clone reduces DC migration by FITC paint and KikGR (Fig. 2 and figs. S3 and S4A), we further probed the necessity of PD-L1:CD80 interactions by using an antibody clone, PD-L1 43H12, which prohibits CD80:PD-L1 inte...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8864075	In this study, the common mechanism of reTFAE in the treatment of lung cancer was studied based on network pharmacology.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "this", "stu...
PMC11244823	The sera No. 29, posC1 and posC2 (Fig 1) reacted with high OD-values against gG1 and gG4 and were selected as positive controls.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9910796	Subviral localization of pEP84R.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Subviral", "localization", "of", "pEP84R", "." ] } ]
PMC11612508	The graphene oxide (GO) NPs were prepared using the Staudenmaier method, and synthesized materials were characterized.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "graphene", "oxide", "(", ...
PMC11774251	Tan-I is a lipophilic diterpene quinone that represents one of the major bioactive constituents in Danshen (Salvia miltiorrhiza).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tan-I", "is", "a", "li...
PMC6461034	Finally, we devised a method to integrate the four analyses as described above and to provide a single metric that can pinpoint active kinases in single biological samples analyzed by phosphoproteomics (Fig 1B, Materials and Methods).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	There were 10 patients with t(4;14), 4 patients with del(17p) and 6 patients with t(14;16).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "were", "10", "patients",...
PMC6160470	Since our results did not lead to a straightforward conclusion about inhibitory mechanism of tested crown ethers, we analysed if they might affect P-gp expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11782780	Therefore, we examined the expression of glycolysis pathway-related proteins in BC cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "we", "examined", "the", "expression", "of", "glycolysis",...
PMC11661024	This characteristic makes postbiotics potentially more stable and consistent in their effects compared to live probiotics.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "characteristic", "makes", "postbiotics", "potentiall...
PMC6222726	The leaves are glabrous, 2.5–7.5 cm long comprising 4 to 9 pairs of leaflets up to 15 mm long and 6 mm wide.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10297204	The sciatic nerve of the thigh has been preferentially selected for in vivo animal experiments .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "sciatic", "nerve", "of", "the", "thigh", "has", ...
PMC10522430	G. applanatum comprises diverse bioactive constituents, notably polysaccharides and triterpenoids [19–24].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "G.", "applanatum", "comprises", "diverse", "bioactive", "constituents", ...
PMC11687167	The MAPK signaling pathway is one of the most important signaling pathways in the eukaryotic signaling network, and its subfamilies mainly include extracellular-signal-regulated kinase (ERK), p38, and C-jun NH2-terminal kinase (JNK).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9220170	Differences were considered significant: * at p < 0.001, at p < 0.01, * at p < 0.05, n/s—differences were not significant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9844987	We observed that low variable promoters are associated with a higher entropy than promoters with high variability (Figure 4A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "observed", ...
PMC11352877	Uterine pathology is more common now than ever before.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Uterine", "pathology", "is", "more", "common", "now", "than", "ever", "before", "." ] } ]
PMC9429973	Methods: Pts were randomized 1:1 to IXA-POM-DEX or POM-DEX and stratified by prior bortezomib exposure, International Staging System stage (1 and 2 vs 3) and the presence of high-risk cytogenetics.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	These findings should be validated in studies with a higher number of patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "findings", "should", "be", "validated", "in", "studies", "with", ...
PMC9454852	Treatment with BOLD-100 alone showed a doubling of calpain activation as compared to the control (CTRL), while the presence of PD150606 completely abolished the effect (Figure 2C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11407042	Freshly recovered bacterial cells are recommended for cytotoxicity assays.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Freshly", "recovered", "bacterial", "cells", "are", "recommended", "for", "cytotoxicity", "assays", "." ...
PMC11703992	C The MR estimates of significant exposures on GCA in test dataset.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "C", "The", "MR", "estimates", "of", "significant", "exposures", "on", "GCA", ...
PMC11021472	This indicates that circZDHHC11 formation was not disturbed by deletion of the miR-150 binding site region (Fig. 3G).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "indicates", ...
PMC4659567	All the signals of the coordinated p-cymene and 7-azaindole-based ligands were found in H (with the appropriate integral intensities) and C NMR spectra recorded on CDCl3 solutions of 1–8 (see Synthesis section).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11714165	p < 0.01 and ****p < 0.0001.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "p", "<", "0.01", "and", "", "", "", "", "p", "<", "0.0001", "." ]...
PMC11354225	Regarding the effect of EGCG on cell proliferation, cells were treated with EGCG 10 µM, 20 µM and 40 µM for 4 h and DNA synthesis was evaluated by flow cytometry.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10810426	Many cells showed multiple co-localization spots with both nucleoporins (Fig 6A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Many", "cells", "showed", "multiple", "co-localization", "spots", "with", "...
PMC11451940	Subsequently, the cells were stained with a ROS/superoxide probe mixture and then incubated at 37 °C in the dark for 60 minutes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11760643	Symbols represent individual experiments.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Symbols", "represent", "individual", "experiments", "." ] } ]
PMC11694066	Boxes, median and lower and upper quartiles; whiskers, the 5th to 95th percentile range; n = 4; two-way ANOVA and post hoc Dunnett test, relative to the siCNTRL DMSO condition.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	I. Marques, C. Sol, A. L. Pinto, E. Aguiar, M. L. Amorim, M. J. Soares, R. Bergantim, P. Gomes, F. Trigo Hematologia Clínica, Centro Hospitalar Universitário São João, Porto, Portugal Background: Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia characterized by the fusion of the PML-RARA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11599565	By the same token, structural proteins βIII-tubulin and Vimentin are upregulated, whereas the epithelial marker EpCAM is downregulated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "By", "the", "same", "t...
PMC8708099	The qPCR was performed under the following conditions: denaturation at 95 °C for 10 min, amplification (20 s at 95 °C, 20s at 60/62/63 °C) and quantification (20 s at 72 °C with a single fluorescence measurement) repeated 45 times, melting curve at 60–95°C with a heating rate of 0.1 °C per second and continuous fluores...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The rates of hematological complications, thrombocytopenia and hepatotoxicity were comparable in three groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "rates", "of", "hematological", "complications", ",", "thrombocy...
PMC9424261	In vivo experiments showed that CA and ferroptosis inducer IKE could inhibit the growth of xenografts, and the inhibition effect was more significant when combined (Fig. 6A–C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7348793	This field is currently heavily dominated by concepts derived from studies of human mtDNA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "field", "is", "currently", "heavily", "dominated", "by", ...
PMC10840195	Due to the poor prognosis of early-stage RCC and resistance to both radiotherapy and chemotherapy, molecular targeted drugs have become the main methods of RCC treatment, and angiogenic receptor tyrosine kinase inhibitors (TKIs) remain the first-line therapy for RCC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11359735	One half was incubated in 0.2 M KOH in methanol and the other in methanol alone, overnight at room temperature.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "half", "wa...
PMC11461833	In the SASP pathway from the Reactome pathway database (https://reactome.org), RPS6KA2, MAPK3, CDK2, UBC, and UBB were downregulated but NFKB1 and ANAPC1 were upregulated in the STXBP5 OE group compared with the control group, consistent with the expression of these genes in senescent cellular phenotypes (Fig. 6F) and ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11237030	Representative bright field images of untransfected (left panel) vs transfected (right panel) CHO-K1 cells at day 0, day 3, day 5, day 7 and day 11 post-transfection with a human AQP5 plasmid.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10957991	This subsequent opening of TRPV4 is responsible for the prolonged increase in calcium levels, initiating pathological events.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "subsequent", "opening", "of", ...
PMC11095939	Real-time PCR to measure mRNA levels of Mecp2. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Real-time", "PCR", "to", "measure", "mRNA", "levels", "of", "Mecp2", ".", "(" ] } ]
PMC11765243	For genotyping parental CD4-Cre p110α mice, q-PCR was performed by using the PowerUp SYBRT Green Master Mix ((Applied BioSystems-ThermoFisher Scientific, Waltham, MA, USA) Ref.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11474209	While investigating the impact of MC-LR on mitochondrial dynamics, the mitochondrial nuclear crosstalk plays a crucial role .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "While", "investigating", "the", "impact", ...
PMC11714165	n = 3. *	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "n", "=", "3", ".", "*" ] } ]
PMC11395280	In the absence of CCR7 ligands, the CCRF-CEM cells did not penetrate the HBEC-5i monolayer (Figure 3C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "absenc...
PMC7582629	Indeed, a small fraction of the incident light undergoes Raman scattering, i.e., less than 1 in 10 to 10 of incident photons, while a large fraction is elastically scattered (Rayleigh scattering).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11612626	Lentiviral particles were produced by co-transfection vector with packaging plasmids pRSV-Rev (Addgene, #12253), pMDLg/pRRE (Addgene, #12251), and pMD2.G–VSVG (Addgene, #12259) in HEK293T cells using lipofectamine.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9352806	The test was performed at least 3 times.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "test", "was", "performed", "at", "least", "3", "times", "." ] } ]
PMC11518702	The specificity of cytokine and immunoreceptor signaling frequently depends upon receptor recruitment of select adaptor proteins and specifically engaged effectors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "specificity", "of", ...
PMC10335954	For the knockdown of TRIP13, two human TRIP13-targeting small interfering RNA (siRNA) sequences were cloned into lentiviral vectors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "the", "kno...
PMC9596868	Quercetin and MST-312 induce cytotoxicity in ovarian cancer cell lines, OSE and HCT116.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O" ], "tokens": [ "Quercetin", "and", "MST-312", "induce", "cytotoxicity", "i...
PMC10850553	Finally, fluorescent images were acquired on a confocal fluorescence microscope system (FV1000 or FV3000, Olympus).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Finally", ",", "fluorescent", "im...
PMC11332076	Neurodegenerative diseases including glaucoma affect insulin signaling, and insulin treatment has been shown to reverse the neurodegenerative loss of dendritic complexity in retinal ganglion cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11247842	We collected GWAS summary statistics from seven partners, including 119,438 records for SCS and 30,689 records for CM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "collected", "GWAS", "summar...
PMC8984067	In the IR spectrum of anti-EpCAM-UCNPs-Ce6 the peaks at 3357, 2936, 1642, 1557, 1445, 1267, 1197, 1121, 909 cm were in line with N-H stretching vibrations and O-H stretching vibrations, C-H stretching vibrations, C=O stretching vibrations in amide, N-H bending vibrations in amide, C-H stretching vibrations, C-N stretch...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11082662	no. ab30912) and anti-ACER2 antibody (1:1,000 dilution; cat.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "no.", "ab30912", ")", "and", "anti-ACER2", "antibody", "(", "1:1,000", "dilution", ";...
PMC11721295	This package computes a running sum statistic that estimates the association of the gene set with the phenotype under study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "package", "computes"...
PMC11394112	As the DLBCL growth progressed, the BL signals increased, and the focal BL signal spread throughout the body.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "the", "DLBCL", "...
PMC11297139	Together, our genome-wide analysis suggested that LLPS of ARID1A activates oncogenes in A673 cells via inducing both the opening of de novo EWS/FLI1-bound cREs and the establishing long-range chromatin contacts.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11676674	In the present study, the phytochemical profile as well as the cytotoxic, genotoxic, and antigenotoxic potential of C. monspeliensis leaf extract from Italian biodiversity against a well-known genotoxic compound, MMC, using CBMN in the CHO-K1 cell line, were investigated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11486946	The fraction of smaller EGFR oligomers was increased with verteporfin concentration, suggesting disassembly of the EGFR oligomers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "fraction", "of", "smaller", "EG...
PMC7294030	Statistical analysis Data are represented as mean ± SD of three independent experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "analysis", "Data", "are", "represented", "as", "mean", "±", ...
PMC11366496	As a result, we suggest and elucidate that RNF122 enhances GBM progression via the JAK2/STAT3/c‐Myc signal pathway and that these molecules may be promising novel targets.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11740207	While exosomes and ABs are distinct entities, they share several features (Table 2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "While", "exosomes", "and", "ABs", "are", "distinct", ...
PMC11693599	In conclusion, the present study demonstrated for the first time that CD109 is secreted from ovarian cancer cell spheroids.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "conclusion", ",", ...
PMC4270159	i. Lab will record an image of the Ponceau-stained membrane.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "i.", "Lab", "will", "record", "an", "image", "of", "the", "Ponceau-stained", "membrane", "...
PMC7185206	Variability of PD-L1 protein-to-mRNA ratios is shown by cancer subtype in a violin plot. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Variability", "of", "PD-L1", "protein-to-mRNA", "ratios", "is", ...
PMC11420784	Transurethral treatment with 35 mM 3-MA for 12 hours before infection reduced the amount of LC3-II in mouse bladders (Supplementary Figure 2A), validating the inhibition effect of 3-MA in the autophagy process in vivo.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Preliminary data shows that when HFE knockout mice were infected with the parasite, their anemic profile improves.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Preliminary", "data", "shows", "that", ...
PMC11680562	Mohammad et al., produced CuO NPs using Vitex negundo and evaluated their anticancer properties by testing them on two types of cancer cells, HepG2 and Hela.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", ...
PMC11365983	Obtained protein samples were normalised using BCA Protein Assay Kit (Thermo), resolved by SDS-PAGE (NuPage 4–12% Bis–Tris gels, Invitrogen), transferred to Immobilon-FL PVDF membranes (EMD Millipore) and blocked with Odyssey TBS Blocking Buffer (Li-Cor).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11089031	Consistent with the findings of Xu et al. , higher mRNA expression of ZNF692 was linked with poor overall survival in ccRCC patients (Fig. 1B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11754094	Two days later, lentivirus-containing medium was collected and filtered through a 0.45-µm syringe filter.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Two", "days", "later", ",", "lentivirus-containing", "medium", ...
PMC9429973	Patients older than 60 years, presented higher percentage of unfavorable ASXL1 (18.6%), RUNX1 (20%) and TP53 (25.7%) mutations with respect to younger (4.8%, 11.9% and 9.5 %) being these differences statistically significant in ASXL 1 and TP 53 (χ p=0.044 and p=0.047 respectively).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11739504	After serum-free treatment, cells were fixed and stained using ICC in a time-course manner.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "serum-free", "treatment", ",", "cells", "were", "f...
PMC11066331	Sinapinic acid (SA), alpha-cyano-4-hydroxycinnamic acid (CHCA), trifluoroacetic acid (TFA), and ammonium bicarbonate (ABC) were purchased from Sigma-Aldrich (Steinheim, Germany).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5035325	Double-expression of EGFR (e) and NeuGcGM3 (h) was detected in both models, Fig. 3.Table 2Co-expression of EGFR and NeuGcGM3 ganglioside in murine modelsEGFRNeuGcGM3Double positivePositive cellsPositive cellsMetastasis modelStaining intensity0123Total (%)Staining intensity0123Total (%)Total (%)3LL-D122-cells2–30012930/...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11155445	Copper-coordinated metallo-supramolecular polymer, a random copolymer, comprises of poly(oligo(ethyleneglycol)ethylacrylate-r-acylthiourea)(P(OEGEA-r-ATU)) (139) having acyl thiourea moiety in side chain and act as a ligand to coordinate with Cu metal (Fig. 66).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Our data suggest that TET2 may exert tumor suppressor functions via controlling the expression of DNA repair genes, or via direct functions of oxidized cytosine species.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10772747	Thus, compounds in EBE that work on PI3K can have inhibitory effects on both the MAPK signaling pathway and the PI3K-Akt signaling pathway, thereby disrupting signaling pathways that contribute to cancer cell proliferation and tumor growth.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11488203	MSC-mediated release of EVs such as microvesicles and exosomes can transport cargo to interacting recipient cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MSC-mediated", "release", "of", "EVs", "such", "as", ...
PMC9429973	HRQoL data were collected at baseline (BL), day 1 of each treatment cycle, end of treatment visit, and during follow-up (every 4 weeks).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11474209	Consuming fish or other foods from contaminated water can expose humans to cyanotoxins, which harm health.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Consuming", "fish", "or", "other", "foods", ...
PMC10547921	The novel analogs combine the characteristics of MMAE and MMAF: high efficiency, bystander activity, and overcoming MDR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "novel", "analogs", ...
PMC11261875	Targeting MCT has emerged as a potential therapeutic strategy in cancer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Targeting", "MCT", "has", "emerged", "as", "a", "potential", "therapeutic", "strategy", ...
PMC10203589	Endometrial cancer (EC) is the most common gynecological malignancy and the fifth most common malignancy in women worldwide (5, 130, 131).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The overall mortality rate was 26.7% (4/15), 75% (3/4) deaths occurred in LAHS patients and there was no death directly related to HLH until data cutoff.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11741577	On days 6 and 12, wound area closure was the most rapid in the FSL-1 treatment groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "On", "days", "6", "and", "12", "...
PMC3931643	Results graphed as a percentage of cells in G1 phase.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", "graphed", "as", "a", "percentage", "of", "cells", "in", "G1", "phase", "." ...
PMC11764090	Additionally, MdERF1B interacts with MdCIbHLH1 to activate MdERF1B-mediated cold tolerance and ethylene biosynthesis .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "MdERF1B", "interacts", "with", "MdCIbHLH1", "to",...
PMC9817179	By imaging different transcription factors (TFs) in live and fixed cells, Schmiedeberg et al., 2009 showed that TFs bound to DNA with fast dissociation dynamics (<5 s residence times as determined by fluorescence recovery after photobleaching [FRAP]) are not cross-linked to DNA upon PFA fixation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11512230

This time, we have used AltMV SP to target Ewing sarcoma (ES) cells, thus expanding the number of SP for anticancer therapy.

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PMC11252033

mRNA was quantified with the ΔΔCt method.

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PMC8427838

Scale bar, 50 µM. The graph is a representative of filopodia formation (based on the localization of moesin-GFP) in RKO cells expressing moesin-GFP (MSN-GFP) alone or co-expressing MSN-GFP with TMIGD1. **

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", ...

PMC11342785

To facilitate the comparison of expression-matched cells, after 3 days, these cells were sorted on an FACSAria cell sorter (BD Biosciences) based on fluorescent protein expression levels for further analysis.

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PMC11770746

The platinum content of each sample was measured by ICP-MS.

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PMC10222971

Cells with damaged membranes are stained, while live cells with intact cell membranes are excluded and do not take up dye; however, this technique has two issues, and the results should be interpreted with caution.

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PMC11188874

The catalytic properties of proteasome subtypes are determined by their catalytic subunit composition.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "catalytic", "properties", "of", "proteasome", "subtypes", "are", "de...

PMC11777207

Having previously established that deletion of CD80 and external ligation of PD-L1 with the αPD-L1 10F9.G2 clone reduces DC migration by FITC paint and KikGR (Fig. 2 and figs. S3 and S4A), we further probed the necessity of PD-L1:CD80 interactions by using an antibody clone, PD-L1 43H12, which prohibits CD80:PD-L1 inte...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8864075

In this study, the common mechanism of reTFAE in the treatment of lung cancer was studied based on network pharmacology.

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PMC11244823

The sera No. 29, posC1 and posC2 (Fig 1) reacted with high OD-values against gG1 and gG4 and were selected as positive controls.

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PMC9910796

Subviral localization of pEP84R.

[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Subviral", "localization", "of", "pEP84R", "." ] } ]

PMC11612508

The graphene oxide (GO) NPs were prepared using the Staudenmaier method, and synthesized materials were characterized.

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PMC11774251

Tan-I is a lipophilic diterpene quinone that represents one of the major bioactive constituents in Danshen (Salvia miltiorrhiza).

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PMC6461034

Finally, we devised a method to integrate the four analyses as described above and to provide a single metric that can pinpoint active kinases in single biological samples analyzed by phosphoproteomics (Fig 1B, Materials and Methods).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

There were 10 patients with t(4;14), 4 patients with del(17p) and 6 patients with t(14;16).

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PMC6160470

Since our results did not lead to a straightforward conclusion about inhibitory mechanism of tested crown ethers, we analysed if they might affect P-gp expression.

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PMC11782780

Therefore, we examined the expression of glycolysis pathway-related proteins in BC cells.

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PMC11661024

This characteristic makes postbiotics potentially more stable and consistent in their effects compared to live probiotics.

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PMC6222726

The leaves are glabrous, 2.5–7.5 cm long comprising 4 to 9 pairs of leaflets up to 15 mm long and 6 mm wide.

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PMC10297204

The sciatic nerve of the thigh has been preferentially selected for in vivo animal experiments .

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PMC10522430

G. applanatum comprises diverse bioactive constituents, notably polysaccharides and triterpenoids [19–24].

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PMC11687167

The MAPK signaling pathway is one of the most important signaling pathways in the eukaryotic signaling network, and its subfamilies mainly include extracellular-signal-regulated kinase (ERK), p38, and C-jun NH2-terminal kinase (JNK).

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PMC9220170

Differences were considered significant: *** at p < 0.001, ** at p < 0.01, * at p < 0.05, n/s—differences were not significant.

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PMC9844987

We observed that low variable promoters are associated with a higher entropy than promoters with high variability (Figure 4A).

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PMC11352877

Uterine pathology is more common now than ever before.

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PMC9429973

Methods: Pts were randomized 1:1 to IXA-POM-DEX or POM-DEX and stratified by prior bortezomib exposure, International Staging System stage (1 and 2 vs 3) and the presence of high-risk cytogenetics.

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PMC9429973

These findings should be validated in studies with a higher number of patients.

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PMC9454852

Treatment with BOLD-100 alone showed a doubling of calpain activation as compared to the control (CTRL), while the presence of PD150606 completely abolished the effect (Figure 2C).

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PMC11407042

Freshly recovered bacterial cells are recommended for cytotoxicity assays.

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PMC11703992

C The MR estimates of significant exposures on GCA in test dataset.

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PMC11021472

This indicates that circZDHHC11 formation was not disturbed by deletion of the miR-150 binding site region (Fig. 3G).

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PMC4659567

All the signals of the coordinated p-cymene and 7-azaindole-based ligands were found in H (with the appropriate integral intensities) and C NMR spectra recorded on CDCl3 solutions of 1–8 (see Synthesis section).

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PMC11714165

p < 0.01 and ****p < 0.0001.

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PMC11354225

Regarding the effect of EGCG on cell proliferation, cells were treated with EGCG 10 µM, 20 µM and 40 µM for 4 h and DNA synthesis was evaluated by flow cytometry.

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PMC10810426

Many cells showed multiple co-localization spots with both nucleoporins (Fig 6A).

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PMC11451940

Subsequently, the cells were stained with a ROS/superoxide probe mixture and then incubated at 37 °C in the dark for 60 minutes.

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PMC11760643

Symbols represent individual experiments.

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PMC11694066

Boxes, median and lower and upper quartiles; whiskers, the 5th to 95th percentile range; n = 4; two-way ANOVA and post hoc Dunnett test, relative to the siCNTRL DMSO condition.

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PMC9429973

I. Marques, C. Sol, A. L. Pinto, E. Aguiar, M. L. Amorim, M. J. Soares, R. Bergantim, P. Gomes, F. Trigo Hematologia Clínica, Centro Hospitalar Universitário São João, Porto, Portugal Background: Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia characterized by the fusion of the PML-RARA.

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PMC11599565

By the same token, structural proteins βIII-tubulin and Vimentin are upregulated, whereas the epithelial marker EpCAM is downregulated.

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PMC8708099

The qPCR was performed under the following conditions: denaturation at 95 °C for 10 min, amplification (20 s at 95 °C, 20s at 60/62/63 °C) and quantification (20 s at 72 °C with a single fluorescence measurement) repeated 45 times, melting curve at 60–95°C with a heating rate of 0.1 °C per second and continuous fluores...

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PMC9429973

The rates of hematological complications, thrombocytopenia and hepatotoxicity were comparable in three groups.

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PMC9424261

In vivo experiments showed that CA and ferroptosis inducer IKE could inhibit the growth of xenografts, and the inhibition effect was more significant when combined (Fig. 6A–C).

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PMC7348793

This field is currently heavily dominated by concepts derived from studies of human mtDNA.

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PMC10840195

Due to the poor prognosis of early-stage RCC and resistance to both radiotherapy and chemotherapy, molecular targeted drugs have become the main methods of RCC treatment, and angiogenic receptor tyrosine kinase inhibitors (TKIs) remain the first-line therapy for RCC.

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PMC11359735

One half was incubated in 0.2 M KOH in methanol and the other in methanol alone, overnight at room temperature.

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PMC11461833

In the SASP pathway from the Reactome pathway database (https://reactome.org), RPS6KA2, MAPK3, CDK2, UBC, and UBB were downregulated but NFKB1 and ANAPC1 were upregulated in the STXBP5 OE group compared with the control group, consistent with the expression of these genes in senescent cellular phenotypes (Fig. 6F) and ...

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PMC11237030

Representative bright field images of untransfected (left panel) vs transfected (right panel) CHO-K1 cells at day 0, day 3, day 5, day 7 and day 11 post-transfection with a human AQP5 plasmid.

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PMC10957991

This subsequent opening of TRPV4 is responsible for the prolonged increase in calcium levels, initiating pathological events.

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PMC11095939

Real-time PCR to measure mRNA levels of Mecp2. (

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PMC11765243

For genotyping parental CD4-Cre p110α mice, q-PCR was performed by using the PowerUp SYBRT Green Master Mix ((Applied BioSystems-ThermoFisher Scientific, Waltham, MA, USA) Ref.

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PMC11474209

While investigating the impact of MC-LR on mitochondrial dynamics, the mitochondrial nuclear crosstalk plays a crucial role .

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PMC11714165

n = 3. *

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PMC11395280

In the absence of CCR7 ligands, the CCRF-CEM cells did not penetrate the HBEC-5i monolayer (Figure 3C).

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PMC7582629

Indeed, a small fraction of the incident light undergoes Raman scattering, i.e., less than 1 in 10 to 10 of incident photons, while a large fraction is elastically scattered (Rayleigh scattering).

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PMC11612626

Lentiviral particles were produced by co-transfection vector with packaging plasmids pRSV-Rev (Addgene, #12253), pMDLg/pRRE (Addgene, #12251), and pMD2.G–VSVG (Addgene, #12259) in HEK293T cells using lipofectamine.

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PMC9352806

The test was performed at least 3 times.

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PMC11518702

The specificity of cytokine and immunoreceptor signaling frequently depends upon receptor recruitment of select adaptor proteins and specifically engaged effectors.

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PMC10335954

For the knockdown of TRIP13, two human TRIP13-targeting small interfering RNA (siRNA) sequences were cloned into lentiviral vectors.

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PMC9596868

Quercetin and MST-312 induce cytotoxicity in ovarian cancer cell lines, OSE and HCT116.

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PMC10850553

Finally, fluorescent images were acquired on a confocal fluorescence microscope system (FV1000 or FV3000, Olympus).

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PMC11332076

Neurodegenerative diseases including glaucoma affect insulin signaling, and insulin treatment has been shown to reverse the neurodegenerative loss of dendritic complexity in retinal ganglion cells.

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PMC11247842

We collected GWAS summary statistics from seven partners, including 119,438 records for SCS and 30,689 records for CM.

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PMC8984067

In the IR spectrum of anti-EpCAM-UCNPs-Ce6 the peaks at 3357, 2936, 1642, 1557, 1445, 1267, 1197, 1121, 909 cm were in line with N-H stretching vibrations and O-H stretching vibrations, C-H stretching vibrations, C=O stretching vibrations in amide, N-H bending vibrations in amide, C-H stretching vibrations, C-N stretch...

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PMC11082662

no. ab30912) and anti-ACER2 antibody (1:1,000 dilution; cat.

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PMC11721295

This package computes a running sum statistic that estimates the association of the gene set with the phenotype under study.

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PMC11394112

As the DLBCL growth progressed, the BL signals increased, and the focal BL signal spread throughout the body.

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PMC11297139

Together, our genome-wide analysis suggested that LLPS of ARID1A activates oncogenes in A673 cells via inducing both the opening of de novo EWS/FLI1-bound cREs and the establishing long-range chromatin contacts.

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PMC11676674

In the present study, the phytochemical profile as well as the cytotoxic, genotoxic, and antigenotoxic potential of C. monspeliensis leaf extract from Italian biodiversity against a well-known genotoxic compound, MMC, using CBMN in the CHO-K1 cell line, were investigated.

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PMC11486946

The fraction of smaller EGFR oligomers was increased with verteporfin concentration, suggesting disassembly of the EGFR oligomers.

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PMC7294030

Statistical analysis Data are represented as mean ± SD of three independent experiments.

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PMC11366496

As a result, we suggest and elucidate that RNF122 enhances GBM progression via the JAK2/STAT3/c‐Myc signal pathway and that these molecules may be promising novel targets.

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PMC11740207

While exosomes and ABs are distinct entities, they share several features (Table 2).

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PMC11693599

In conclusion, the present study demonstrated for the first time that CD109 is secreted from ovarian cancer cell spheroids.

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PMC4270159

i. Lab will record an image of the Ponceau-stained membrane.

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PMC7185206

Variability of PD-L1 protein-to-mRNA ratios is shown by cancer subtype in a violin plot. (

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PMC11420784

Transurethral treatment with 35 mM 3-MA for 12 hours before infection reduced the amount of LC3-II in mouse bladders (Supplementary Figure 2A), validating the inhibition effect of 3-MA in the autophagy process in vivo.

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PMC9429973

Preliminary data shows that when HFE knockout mice were infected with the parasite, their anemic profile improves.

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PMC11680562

Mohammad et al., produced CuO NPs using Vitex negundo and evaluated their anticancer properties by testing them on two types of cancer cells, HepG2 and Hela.

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PMC11365983

Obtained protein samples were normalised using BCA Protein Assay Kit (Thermo), resolved by SDS-PAGE (NuPage 4–12% Bis–Tris gels, Invitrogen), transferred to Immobilon-FL PVDF membranes (EMD Millipore) and blocked with Odyssey TBS Blocking Buffer (Li-Cor).

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PMC11089031

Consistent with the findings of Xu et al. , higher mRNA expression of ZNF692 was linked with poor overall survival in ccRCC patients (Fig. 1B).

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PMC11754094

Two days later, lentivirus-containing medium was collected and filtered through a 0.45-µm syringe filter.

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PMC9429973

Patients older than 60 years, presented higher percentage of unfavorable ASXL1 (18.6%), RUNX1 (20%) and TP53 (25.7%) mutations with respect to younger (4.8%, 11.9% and 9.5 %) being these differences statistically significant in ASXL 1 and TP 53 (χ p=0.044 and p=0.047 respectively).

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PMC11739504

After serum-free treatment, cells were fixed and stained using ICC in a time-course manner.

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PMC11066331

Sinapinic acid (SA), alpha-cyano-4-hydroxycinnamic acid (CHCA), trifluoroacetic acid (TFA), and ammonium bicarbonate (ABC) were purchased from Sigma-Aldrich (Steinheim, Germany).

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PMC5035325

Double-expression of EGFR (e) and NeuGcGM3 (h) was detected in both models, Fig. 3.Table 2Co-expression of EGFR and NeuGcGM3 ganglioside in murine modelsEGFRNeuGcGM3Double positivePositive cellsPositive cellsMetastasis modelStaining intensity0123Total (%)Staining intensity0123Total (%)Total (%)3LL-D122-cells2–30012930/...

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PMC11155445

Copper-coordinated metallo-supramolecular polymer, a random copolymer, comprises of poly(oligo(ethyleneglycol)ethylacrylate-r-acylthiourea)(P(OEGEA-r-ATU)) (139) having acyl thiourea moiety in side chain and act as a ligand to coordinate with Cu metal (Fig. 66).

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PMC9429973

Our data suggest that TET2 may exert tumor suppressor functions via controlling the expression of DNA repair genes, or via direct functions of oxidized cytosine species.

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PMC10772747

Thus, compounds in EBE that work on PI3K can have inhibitory effects on both the MAPK signaling pathway and the PI3K-Akt signaling pathway, thereby disrupting signaling pathways that contribute to cancer cell proliferation and tumor growth.

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PMC11488203

MSC-mediated release of EVs such as microvesicles and exosomes can transport cargo to interacting recipient cells.

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PMC9429973

HRQoL data were collected at baseline (BL), day 1 of each treatment cycle, end of treatment visit, and during follow-up (every 4 weeks).

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PMC11474209

Consuming fish or other foods from contaminated water can expose humans to cyanotoxins, which harm health.

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PMC10547921

The novel analogs combine the characteristics of MMAE and MMAF: high efficiency, bystander activity, and overcoming MDR.

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PMC11261875

Targeting MCT has emerged as a potential therapeutic strategy in cancer.

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PMC10203589

Endometrial cancer (EC) is the most common gynecological malignancy and the fifth most common malignancy in women worldwide (5, 130, 131).

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PMC9429973

The overall mortality rate was 26.7% (4/15), 75% (3/4) deaths occurred in LAHS patients and there was no death directly related to HLH until data cutoff.

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PMC11741577

On days 6 and 12, wound area closure was the most rapid in the FSL-1 treatment groups.

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PMC3931643

Results graphed as a percentage of cells in G1 phase.

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PMC11764090

Additionally, MdERF1B interacts with MdCIbHLH1 to activate MdERF1B-mediated cold tolerance and ethylene biosynthesis .

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PMC9817179

By imaging different transcription factors (TFs) in live and fixed cells, Schmiedeberg et al., 2009 showed that TFs bound to DNA with fast dissociation dynamics (<5 s residence times as determined by fluorescence recovery after photobleaching [FRAP]) are not cross-linked to DNA upon PFA fixation.

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