OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11754784	We first constructed the DNA cage via hybridization-driven assembly.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "first", "constructed", "the", "DNA", "cage", "via", "hybridization-driven", "assembly", "." ] }...
PMC11768927	These results suggest that combining oncolytic virotherapy with IFN-α2a may enhance VSV selectivity for cancer cells, warranting further investigation into the roles of different IFN subtypes in improving the therapy’s efficacy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11126803	E, clinical sample test results show that the mRNA level of LncRNA-SERB in cancer tissues is higher than that in para-cancerous normal tissues from our collections.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11011837	It is interesting to note that most of the chain lengths are statistically different: particularly, 18 and 20 carbon-atom chains are highly present in Molt-4 and Molt-16.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11515150	The capacity of VHH library performing in E.coli TG1 strain was calculated by counting the numbers of colony after gradient dilution.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "capacity", ...
PMC5417661	The compound’s permeability was ranked to be high and no significant efflux was observed (Table 2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "compound", "’s", "permeabi...
PMC11544771	Furthermore, the combined treatment also increased the levels of cleaved caspase 3 and cleaved PARP, two markers of apoptosis, compared to treatment with CPX alone.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11477621	C NMR (150 MHz, CDCl3) δ 173.7, 134.7, 130.3, 129.0, 124.3, 123.5, 112.6, 110.9, 100.7, 60.4, 46.6, 34.3, 30.1, 28.8, 26.7, 24.8, 14.4.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11519583	7.	[ { "tags": [ "O", "O" ], "tokens": [ "7", "." ] } ]
PMC11790599	Pre-treatment with BafA1 effectively blocked cell death (Figures 4D, E) and the formation of cytoplasmic vacuolization (Figure 4F) induced by TSL in both SK-BR-3 and ZR-75-1 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11474209	Advantages - Various immobilization and sensor creation methodologies for signal transduction, catalysis, and amplification.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Advantages", "-", "Various", "immobilization", "and", ...
PMC6461034	Therefore, we decided not to incorporate the iBAQ approach into INKA; see also Appendix Fig S13.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "we", "decided", "not...
PMC11352877	However, VEGFRs are expressed not only in vascular endothelial cells but also in macrophages and monocytes , which suggests that they have a role in immune responses.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11413393	b Western blots for indicated proteins in RCC243 cells with dox-inducible PRMT1-shRNAs treated with or without Dox for 4 days.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "b", "Western", "blo...
PMC11240448	Only these models, referred to as digital cell twins, can predict whether drug treatments are synergistic, antagonistic, or merely additive .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11321678	In this study, we used K‐means unsupervised clustering to analyze the expression of 94 reported NTRs in the same cohort of 763 MB samples.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	Survival outcomes were assessed by the Kaplan-Meier method.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Survival", "outcomes", "were", "assessed", "by", "the", "Kaplan-Meier", "method", "." ] } ]
PMC11237030	Therefore, screening for anti-AQP5 autoantibodies in SS patients might help to define a subset of patients and introduce targeted therapies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", ...
PMC11320834	The main mechanism of action is through decreasing the expression of the HDR factors BRCA1/2 and RAD51 recombinase.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "main", "mechanism", "of", "acti...
PMC11604015	Knocking out target genes is an effective way to decrease the expression of surface proteins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Knocking", "out", "target", "genes", "is", "an", "effective...
PMC9596868	Further, the in vivo binding activity of MST-312 with DNA needs experimental confirmation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Further", ",", "the", "in", "vivo", "binding", "activity", "of",...
PMC11591038	Recently, it was shown that gut dysbiosis, or disturbance in the gut microbiota, can lead to inflammation and is associated with the pathogenesis of various diseases including AD .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11129910	To understand the significance of the loss of RAB25 expression in spindle cell breast cancer, we expanded our study to look at the expression of RAB25 in clinical samples.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11514418	Additionally, the incidences of leukopenia, thrombocytopenia, and fatigue in patients receiving the combined therapy of APS and GS were significantly lower than those in patients receiving the monotherapy of GS alone (17.07%, 9.76%, 31.71% vs 37.50%, 28.57%, 60.71%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10968586	A lot of experimental data in vivo and in vitro have definitively demonstrated the ROS scavenger ability of OLE and HT, which can also act on antioxidant cellular mechanisms restoring ROS homeostasis, including promotion of the increase in reduced glutathione levels (GSH), depletion of lipid peroxidation product malond...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Eight (18%) participants with a PC drop following D1+D2 had had a previous splenectomy (same as the 22% overall).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC7338939	Notch suppression by gamma-secretase inhibitors is a valid approach against melanoma.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notch", "suppression", "by", "gamma-secretase", "inhibitors", "is", "a", "valid", "approach...
PMC2118063	ChIP analyses were performed with mouse NFS-202 cells or purified human tonsillar B cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ChIP", "analyses", "were", "performed", "with", "mouse", "NFS...
PMC7582629	This method is in-house algorithm, which generates loadings similar to spectra, which are easier to chemically/physically code.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "method", "is", "in-house"...
PMC9429973	There were differences between treatment cohorts with respect to comorbidities.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "were", "differences", "between", "treatment", "cohorts", "with", "respect", "to", "como...
PMC7868205	The examination of the structure and crystalline size of the biosynthesized AgNPs was performed using XRD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "examination", "of", "the", "structure", "and", ...
PMC11775197	Figure 1 shows the role of PPARα in CRC.Fig.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Figure", "1", "shows", "the", "role", "of", "PPARα", "in", "CRC.Fig", "." ] } ]
PMC8414691	From top to bottom: DAPI (blue), EGFP::α-Tubulin (green) and merge.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "From", "top", "to", "bottom", ":", "DAPI", "(", ...
PMC10818573	Eventually, we split the above amplification step into two steps.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Eventually", ",", "we", "split", "the", "above", "amplification", "step", "into", "tw...
PMC9429973	The immunoglobulin (IG) and T-cell receptor loci are enhancer-rich regions that are commonly hijacked via translocation in many subtypes of lymphoid malignancies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11502327	An important characteristic of natural medicines compared to synthetic chemicals is that they contain a large variety of complex scaffolds, generally giving them higher molecular weight, more oxygen and carbon atoms, and fewer halogen and nitrogen atoms (27).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The median time from diagnosis to ASCT was 4 months; 90% had early ASCT (within 1 year of diagnosis) and 57% received upfront ASCT without prior induction.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10870498	A The succinylation sites for KIF23 were predicted using the SuccinSite and GPSuc databases; B IP assay was used to analyze the succinylation sites of KIF23; C The HEK-293T cells transfected with an empty vector and SIRT7 overexpression vector were treated with CHX, then the protein expression of KIF23 was assayed by w...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11775197	This rising trend may be related to risk factors .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "rising", "trend", "may", "be", "related", "to", "risk", "factors", "." ] } ]
PMC8409415	Platinum‐resistant cell lines were designated as A2780cisR and SKOV3cisR, and the paclitaxel‐resistant cell line was designated as A2780pacR. The cells were prepared as described previously., , , ,	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC9429973	Future studies will need to address comprehensively the phenotypic spectrum of the disease and genetic and non-genetic modifiers of clinical phenotypes and severity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Future"...
PMC11750712	Study participants receive lymphodepletion with fludarabine (Flu) and cyclophosphamide (Cy) before AUTO4 infusion, which is administered as a single intravenous infusion.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973	However, CAR-T post first allogeneic hematopoietic stem cell transplantation (allo-HSCT), donor cells would involve to patients’ immune system, even if same donors’ lymphocytes were used to produce CAR-T cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10743717	On the other hand, HADH deficiency known by clinicians as short-chain 3-hydroxyacyl-CoA dehydrogenase (SCHAD) deficiency (OMIM#231530) is a fatty acid oxidation disorder causing hyperinsulinism in pediatric patients , unrelated to 17β-HSD10 indeed even if both could catalyze the oxidation of acyl-CoA derivatives in mit...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11512230	When comparing the adsorption effectiveness of different SP within a single cell line, both TMV SP and AltMV SPV adsorbed on the surface of all cell lines (Figure 3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11687663	The 3D structure of the protein was obtained from the Protein Data Bank (PDB) (https://www.rcsb.org/) and subjected to purification using BIOVIA Discovery Studio 2021 to eliminate water molecules, heteroatoms, and undesired ligands.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The associated TRIBECA (TReatment Interruption of BTKi to Enhance COVID-19 Antibody response) study sought to determine if a superior immune response could be gained by pause of BTKi therapy prior to and up to 4 weeks after 3 vaccine dose.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11538390	However, the vector harboring the derived risk allele of rs570516915 showed significantly reduced activity relative to the one harboring the non-risk allele (P = 0.0002) (Fig. 4b).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11190538	The collected supernatant was then stored at 2 °C and further used to evaluate the samples’ total phenolic content and antioxidant activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9966931	Essential oils (EOs) are among the most valuable fractions obtained from these aromatic species, comprising complex mixtures of secondary plant metabolites, including terpenoids and aromatic compounds.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Response to treatment after 3-4 cycles, discriminate two groups of patients with an OS of 12.66 months in those patients who achieved CR or PR vs 2.4 months in non-responders (p0.000).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11638255	Given the critical importance of copper for effective immune function, we sought to investigate changes in copper metabolism within the immune compartment using our single-cell transcriptomics data.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10530622	Currently, there are two potential targets for the treatment of PH: glycolate oxidase (GO) and the major hepatic form of LDH.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11747949	Interestingly CCR2 antagonist upregulates HIF1A and CAIX expression in hypoxia, but decreases VEGF and angiopoietin‐like 4 (ANGPTL4) expressions (Figure 4B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	In primary cells, the delay in erythroid differentiation was accompanied by drastic changes in the transcriptomic profile of primary cells as shown by RNAseq.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	Also, there were no significant differences in number of cycles with R-DA-EPOCH dose escalation, reduction, anemia, thrombocytopenia, neutropenia, febrile neutropenia and septic complications.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10747160	The 96-well plate was returned to the 37 °C humidified incubator at 4.5% CO2 in order to allow the 3t3 cells to adhere and recover for 8–12 h. For trans-infectivity tests with Griffithsin inhibitors, two different protocols were tested: Griffithsin pre-incubated with virus and Griffithsin pre-incubated with 3t3 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", ...
PMC11087766	The solid line depicts the mean across n = 12 replicates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "solid", "line", "depicts", "the", "mean", "across", "n", "=", "12", "rep...
PMC10114490	The results show that the predictive model based on the metabolome changes of diHLC-T cells has higher accuracy in classifying toxicity than HepG2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O" ], "tokens"...
PMC11711345	There was neither enhanced apoptosis nor necrosis of Calu-3 cells after treatment with cuminaldehyde at 100 µM (p > 0.05) for 24h and 48h, as determined by flow cytometry analysis (Annexin V/propidium iodide) (Figure 4).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11803149	Left, schematic diagrams show the experimental design (created with BioRender.com).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Left", ",", "schematic", "diagrams", "show", "the", "experimental", "design...
PMC9847912	Briefly, CEMss cells were seeded into microtiter plates, dosed with varying concentrations of GSK232, infected, and cultured for six days.	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "token...
PMC10887351	As previously reported, stress is significantly involved in tumorigenesis, through CAs acting at the β-AR level, including β1- β2- and β3-ARs, where the β-AR antagonists seem to reduce tumor growth and progression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6461034	Kinase node colors correlate with INKA scores in a white to red gradient, and kinases with at least one phosphorylated activation loop phosphosite are indicated by a thicker node border.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Secondary and exploratory endpoints include the effect of FTX-6058 on HbF induction in peripheral blood and other relevant SCD biomarkers and clinical endpoints.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Seconda...
PMC11472639	indicates a significant difference from ‘15-min’ and p < 0.001.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "indicates", "a", "significant", "difference", "from", "‘", "15-min", "’", "and",...
PMC10565698	Stained tissue sections were observed under a light microscope and photographed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Stained", "tissue", "sections", "were", "observed", "under", "a", "light", "microscope", ...
PMC10988555	For this, the A2780 cell line was cultivated in 25 cm T-flasks at a density of 2 × 10 cells/mL and incubated for 24 h in the conditions described above.	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9219615	A cell’s DAPI signal is directly proportional to the amount of cellular DNA such that G0/G1 < S < G2/M, hence DAPI fluorescence intensity was used to quantify the percentage of cells in each phase of the cycle for each sample.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10898159	FOXF1, ETV1 and HIC1 together form the core TF network in GIST binding enhancer and/or promoter and then promoting KIT expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "FOXF1", ",",...
PMC9429973	Overall response (ORR) rate was 94% (15/16) and a complete response (CR) rate was 75% (12/16).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11658074	Scale bars = 100 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bars", "=", "100", "μm", "." ] } ]
PMC8998437	The type III BL cell lines expressed activation markers, corresponding to the immunoblastic phenotype (CD39-positive) and downregulated CD10 (the GC marker); expressed EBNA1 to EBNA5; and were growing in clumps.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11779605	All spheroids from each 96-well plate were pooled and injected into the peritoneal cavity of 6- to 8-week-old female C57BL/6NHsd mice using a 21-gauge needle (N = 13–14 per group, Envigo).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", ...
PMC11711063	ZG16B expression was diminished in the xenografts from Bex + Carv‐treated mice in the proliferating areas, relative to controls (Figure 5G).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11628309	Rodents constitute the main in vivo models, which account for 85% of animal studies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Rodents", "constitute", "the", "main", "in", "vivo", ...
PMC10813895	In luminal A BC-subtype cell lines MCF-7 and T47D, ELF5 expression inhibits proliferation, whereas ELF5 promotes cell proliferation in basal-like BC cell lines, suggesting that the role of ELF5 could be cancer subtype-dependent .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11794568	OCR was measured in control and SK-MEL-2 cells stably overexpressing CRIP1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O" ], "tokens": [ "OCR", "was", "measured", "in", "control", "and", "SK-MEL-2", "cells", "stably", ...
PMC11670954	Caco-2 cells (1 × 10/200 μL) were seeded into the upper chambers of a 24-well Transwell plate (3470, Costar, Corning), and 1.5 mL of fresh medium was added to the lower chambers.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Inclusion critheria were age>18years,no other causes of anemia,Hb<10g/dl, ferritin<30ng/ml,TSAT<20%, 1FOBT+/3 with EGDS and PCS normal,no neoplastic hypermenorrhea and/or menometrorrhagia,gastric bleeding(ulcer, gastritis, angiodysplasia),small intestine bleeding(angiodysplasia),Colon bleeding (diverticulitis, angiodys...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	A majority of low-risk patients (45/63; 71.4%) did not receive letermovir.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "majority", "of", "low-risk", "patients", "(", "45/63",...
PMC11499955	Furthermore, the levels of overexpressed protein receptors not only differ within the cancer types (10 to 10 receptors per cell) but also vary within the different patient tumour lesions as well as from patient to patient.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9874064	Specifically, in BEL-7404 cells, the IC50 of NP-Pt-USP1i, NP-Pt and cisplatin are 2.3 μM,7.6 μM, and ＞40 μM, respectively (Fig. 3B).	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11628309	Additionally, other types of fetal serum, such as horse (blue) and calf (cyan), have also been utilized.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11783017	B, C) ELISA analysis of CCL2 and IL13 expression levels in 143B cells. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "B", ",", "C", ")", "ELISA", "analysis", ...
PMC9429973	The subsequent analysis after patient received at least two dose of the vaccination shows a less severe lymphopenia (P< 0.05) and disease severity O. Gelo, L. Korin, L. Ayala, S. Cranco, E. Babuin, A. Vitriu, P. Ochoa, M. L. Fuente, N. Tartas, M. Alderete, S. Flagel, C. Sosa, M. A. Gazzaneo, M. Zylberman, F. Díaz Couse...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8903741	Twenty plates per transfection were screened.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Twenty", "plates", "per", "transfection", "were", "screened", "." ] } ]
PMC9429973	Although thrombosis can affect any anatomical site, the most frequent sites include intra-abdominal and cerebral veins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Although", "thrombosis", "can", "affect", "any", ...
PMC11632064	Data are relative to MeWo basal conditions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "relative", "to", "MeWo", "basal", "conditions", "." ] } ]
PMC10656496	Total RNA was prepared from each osteosarcoma cell line using the mirVana miRNA Isolation Kit (Cat# AM1560, Invitrogen, Thermo Fisher) and RNA-sequencing libraries were prepared using the Nugen Ovation Human FFPE RNA-seq Multiplex System according to the manufacturer’s protocol (Tecan Genomics, Inc, Redwood City, CA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC11395280	To determine if CCL198-83 disrupted not only receptor internalization but also signaling in CCRF-CEM T-ALL via CCR7, we used Ca mobilization assays.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC10729469	Overall, the results demonstrate that treatment with amyloid β-specific TCRAβ-Tregs improves memory outcomes in APP/PS1 mice compared to treatment with polyclonal Tregs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Overall...
PMC11538390	Primer sequences are shown in Supplementary Data 11.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Primer", "sequences", "are", "shown", "in", "Supplementary", "Data", "11", "." ] } ]
PMC11344246	Using these data, the largest connected component of this full PPI graph contained 659 genes with 820 edges between them.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Using", "these", ...
PMC11422150	Additionally, non-lymphocytic Ly6GCD11bF4/80Ly6C cells, so-called inflammatory M1 macrophages, were also significantly suppressed in the hAMSC group (290 ± 55 cells, P = 0.044) than in the untreated SCI group (430 ± 42 cells, Figure 6C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11281366	Total cellular RNAs were extracted using RNeasy RNA extraction columns (Qiagen) according to the manufacturer’s instructions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Total", "cellular", "RNAs", "were...
PMC11787355	and analgesia (Carprofen, 5 mg/kg s.c.).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "and", "analgesia", "(", "Carprofen", ",", "5", "mg/kg", "s.c", ".", ")", "." ] } ]
PMC11637276	Data was normalised between the average of the non-targeting (NT) control and NT in the presence of Bafilomycin A1, as a positive control to assess the magnitude of modulation between technical replicates, as in .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6114978	No additive effect of adding 5-azacytidine and trichostatin-A was identified in the sarcoma cell lines. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "additive", "effect", "of", "adding", "5-azacytid...
PMC9325715	Freundlich model belongs to the oldest and most commonly used isotherm expressions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Freundlich", "model", "belongs", "to", "the", "oldest", "and", "most", "commonly...

PMC11754784

We first constructed the DNA cage via hybridization-driven assembly.

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PMC11768927

These results suggest that combining oncolytic virotherapy with IFN-α2a may enhance VSV selectivity for cancer cells, warranting further investigation into the roles of different IFN subtypes in improving the therapy’s efficacy.

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PMC11126803

E, clinical sample test results show that the mRNA level of LncRNA-SERB in cancer tissues is higher than that in para-cancerous normal tissues from our collections.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11011837

It is interesting to note that most of the chain lengths are statistically different: particularly, 18 and 20 carbon-atom chains are highly present in Molt-4 and Molt-16.

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PMC11515150

The capacity of VHH library performing in E.coli TG1 strain was calculated by counting the numbers of colony after gradient dilution.

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PMC5417661

The compound’s permeability was ranked to be high and no significant efflux was observed (Table 2).

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PMC11544771

Furthermore, the combined treatment also increased the levels of cleaved caspase 3 and cleaved PARP, two markers of apoptosis, compared to treatment with CPX alone.

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PMC11477621

C NMR (150 MHz, CDCl3) δ 173.7, 134.7, 130.3, 129.0, 124.3, 123.5, 112.6, 110.9, 100.7, 60.4, 46.6, 34.3, 30.1, 28.8, 26.7, 24.8, 14.4.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11519583

7.

[ { "tags": [ "O", "O" ], "tokens": [ "7", "." ] } ]

PMC11790599

Pre-treatment with BafA1 effectively blocked cell death (Figures 4D, E) and the formation of cytoplasmic vacuolization (Figure 4F) induced by TSL in both SK-BR-3 and ZR-75-1 cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11474209

Advantages - Various immobilization and sensor creation methodologies for signal transduction, catalysis, and amplification.

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PMC6461034

Therefore, we decided not to incorporate the iBAQ approach into INKA; see also Appendix Fig S13.

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PMC11352877

However, VEGFRs are expressed not only in vascular endothelial cells but also in macrophages and monocytes , which suggests that they have a role in immune responses.

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PMC11413393

b Western blots for indicated proteins in RCC243 cells with dox-inducible PRMT1-shRNAs treated with or without Dox for 4 days.

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PMC11240448

Only these models, referred to as digital cell twins, can predict whether drug treatments are synergistic, antagonistic, or merely additive .

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PMC11321678

In this study, we used K‐means unsupervised clustering to analyze the expression of 94 reported NTRs in the same cohort of 763 MB samples.

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PMC9429973

Survival outcomes were assessed by the Kaplan-Meier method.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Survival", "outcomes", "were", "assessed", "by", "the", "Kaplan-Meier", "method", "." ] } ]

PMC11237030

Therefore, screening for anti-AQP5 autoantibodies in SS patients might help to define a subset of patients and introduce targeted therapies.

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PMC11320834

The main mechanism of action is through decreasing the expression of the HDR factors BRCA1/2 and RAD51 recombinase.

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PMC11604015

Knocking out target genes is an effective way to decrease the expression of surface proteins.

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PMC9596868

Further, the in vivo binding activity of MST-312 with DNA needs experimental confirmation.

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PMC11591038

Recently, it was shown that gut dysbiosis, or disturbance in the gut microbiota, can lead to inflammation and is associated with the pathogenesis of various diseases including AD .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11129910

To understand the significance of the loss of RAB25 expression in spindle cell breast cancer, we expanded our study to look at the expression of RAB25 in clinical samples.

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PMC11514418

Additionally, the incidences of leukopenia, thrombocytopenia, and fatigue in patients receiving the combined therapy of APS and GS were significantly lower than those in patients receiving the monotherapy of GS alone (17.07%, 9.76%, 31.71% vs 37.50%, 28.57%, 60.71%).

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PMC10968586

A lot of experimental data in vivo and in vitro have definitively demonstrated the ROS scavenger ability of OLE and HT, which can also act on antioxidant cellular mechanisms restoring ROS homeostasis, including promotion of the increase in reduced glutathione levels (GSH), depletion of lipid peroxidation product malond...

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PMC9429973

Eight (18%) participants with a PC drop following D1+D2 had had a previous splenectomy (same as the 22% overall).

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PMC7338939

Notch suppression by gamma-secretase inhibitors is a valid approach against melanoma.

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PMC2118063

ChIP analyses were performed with mouse NFS-202 cells or purified human tonsillar B cells.

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PMC7582629

This method is in-house algorithm, which generates loadings similar to spectra, which are easier to chemically/physically code.

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PMC9429973

There were differences between treatment cohorts with respect to comorbidities.

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PMC7868205

The examination of the structure and crystalline size of the biosynthesized AgNPs was performed using XRD.

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PMC11775197

Figure 1 shows the role of PPARα in CRC.Fig.

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PMC8414691

From top to bottom: DAPI (blue), EGFP::α-Tubulin (green) and merge.

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PMC10818573

Eventually, we split the above amplification step into two steps.

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PMC9429973

The immunoglobulin (IG) and T-cell receptor loci are enhancer-rich regions that are commonly hijacked via translocation in many subtypes of lymphoid malignancies.

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PMC11502327

An important characteristic of natural medicines compared to synthetic chemicals is that they contain a large variety of complex scaffolds, generally giving them higher molecular weight, more oxygen and carbon atoms, and fewer halogen and nitrogen atoms (27).

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PMC9429973

The median time from diagnosis to ASCT was 4 months; 90% had early ASCT (within 1 year of diagnosis) and 57% received upfront ASCT without prior induction.

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PMC10870498

A The succinylation sites for KIF23 were predicted using the SuccinSite and GPSuc databases; B IP assay was used to analyze the succinylation sites of KIF23; C The HEK-293T cells transfected with an empty vector and SIRT7 overexpression vector were treated with CHX, then the protein expression of KIF23 was assayed by w...

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PMC11775197

This rising trend may be related to risk factors .

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PMC8409415

Platinum‐resistant cell lines were designated as A2780cisR and SKOV3cisR, and the paclitaxel‐resistant cell line was designated as A2780pacR. The cells were prepared as described previously., , , ,

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PMC9429973

Future studies will need to address comprehensively the phenotypic spectrum of the disease and genetic and non-genetic modifiers of clinical phenotypes and severity.

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PMC11750712

Study participants receive lymphodepletion with fludarabine (Flu) and cyclophosphamide (Cy) before AUTO4 infusion, which is administered as a single intravenous infusion.

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PMC9429973

However, CAR-T post first allogeneic hematopoietic stem cell transplantation (allo-HSCT), donor cells would involve to patients’ immune system, even if same donors’ lymphocytes were used to produce CAR-T cells.

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PMC10743717

On the other hand, HADH deficiency known by clinicians as short-chain 3-hydroxyacyl-CoA dehydrogenase (SCHAD) deficiency (OMIM#231530) is a fatty acid oxidation disorder causing hyperinsulinism in pediatric patients , unrelated to 17β-HSD10 indeed even if both could catalyze the oxidation of acyl-CoA derivatives in mit...

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PMC11512230

When comparing the adsorption effectiveness of different SP within a single cell line, both TMV SP and AltMV SPV adsorbed on the surface of all cell lines (Figure 3).

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PMC11687663

The 3D structure of the protein was obtained from the Protein Data Bank (PDB) (https://www.rcsb.org/) and subjected to purification using BIOVIA Discovery Studio 2021 to eliminate water molecules, heteroatoms, and undesired ligands.

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PMC9429973

The associated TRIBECA (TReatment Interruption of BTKi to Enhance COVID-19 Antibody response) study sought to determine if a superior immune response could be gained by pause of BTKi therapy prior to and up to 4 weeks after 3 vaccine dose.

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PMC11538390

However, the vector harboring the derived risk allele of rs570516915 showed significantly reduced activity relative to the one harboring the non-risk allele (P = 0.0002) (Fig. 4b).

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PMC11190538

The collected supernatant was then stored at 2 °C and further used to evaluate the samples’ total phenolic content and antioxidant activity.

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PMC9966931

Essential oils (EOs) are among the most valuable fractions obtained from these aromatic species, comprising complex mixtures of secondary plant metabolites, including terpenoids and aromatic compounds.

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PMC9429973

Response to treatment after 3-4 cycles, discriminate two groups of patients with an OS of 12.66 months in those patients who achieved CR or PR vs 2.4 months in non-responders (p0.000).

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PMC11638255

Given the critical importance of copper for effective immune function, we sought to investigate changes in copper metabolism within the immune compartment using our single-cell transcriptomics data.

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PMC10530622

Currently, there are two potential targets for the treatment of PH: glycolate oxidase (GO) and the major hepatic form of LDH.

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PMC11747949

Interestingly CCR2 antagonist upregulates HIF1A and CAIX expression in hypoxia, but decreases VEGF and angiopoietin‐like 4 (ANGPTL4) expressions (Figure 4B).

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PMC9429973

In primary cells, the delay in erythroid differentiation was accompanied by drastic changes in the transcriptomic profile of primary cells as shown by RNAseq.

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PMC9429973

Also, there were no significant differences in number of cycles with R-DA-EPOCH dose escalation, reduction, anemia, thrombocytopenia, neutropenia, febrile neutropenia and septic complications.

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PMC10747160

The 96-well plate was returned to the 37 °C humidified incubator at 4.5% CO2 in order to allow the 3t3 cells to adhere and recover for 8–12 h. For trans-infectivity tests with Griffithsin inhibitors, two different protocols were tested: Griffithsin pre-incubated with virus and Griffithsin pre-incubated with 3t3 cells.

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PMC11087766

The solid line depicts the mean across n = 12 replicates.

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PMC10114490

The results show that the predictive model based on the metabolome changes of diHLC-T cells has higher accuracy in classifying toxicity than HepG2.

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PMC11711345

There was neither enhanced apoptosis nor necrosis of Calu-3 cells after treatment with cuminaldehyde at 100 µM (p > 0.05) for 24h and 48h, as determined by flow cytometry analysis (Annexin V/propidium iodide) (Figure 4).

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PMC11803149

Left, schematic diagrams show the experimental design (created with BioRender.com).

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PMC9847912

Briefly, CEMss cells were seeded into microtiter plates, dosed with varying concentrations of GSK232, infected, and cultured for six days.

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PMC10887351

As previously reported, stress is significantly involved in tumorigenesis, through CAs acting at the β-AR level, including β1- β2- and β3-ARs, where the β-AR antagonists seem to reduce tumor growth and progression.

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PMC6461034

Kinase node colors correlate with INKA scores in a white to red gradient, and kinases with at least one phosphorylated activation loop phosphosite are indicated by a thicker node border.

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PMC9429973

Secondary and exploratory endpoints include the effect of FTX-6058 on HbF induction in peripheral blood and other relevant SCD biomarkers and clinical endpoints.

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PMC11472639

indicates a significant difference from ‘15-min’ and p < 0.001.

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PMC10565698

Stained tissue sections were observed under a light microscope and photographed.

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PMC10988555

For this, the A2780 cell line was cultivated in 25 cm T-flasks at a density of 2 × 10 cells/mL and incubated for 24 h in the conditions described above.

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PMC9219615

A cell’s DAPI signal is directly proportional to the amount of cellular DNA such that G0/G1 < S < G2/M, hence DAPI fluorescence intensity was used to quantify the percentage of cells in each phase of the cycle for each sample.

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PMC10898159

FOXF1, ETV1 and HIC1 together form the core TF network in GIST binding enhancer and/or promoter and then promoting KIT expression.

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PMC9429973

Overall response (ORR) rate was 94% (15/16) and a complete response (CR) rate was 75% (12/16).

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PMC11658074

Scale bars = 100 μm.

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PMC8998437

The type III BL cell lines expressed activation markers, corresponding to the immunoblastic phenotype (CD39-positive) and downregulated CD10 (the GC marker); expressed EBNA1 to EBNA5; and were growing in clumps.

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PMC11779605

All spheroids from each 96-well plate were pooled and injected into the peritoneal cavity of 6- to 8-week-old female C57BL/6NHsd mice using a 21-gauge needle (N = 13–14 per group, Envigo).

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PMC11711063

ZG16B expression was diminished in the xenografts from Bex + Carv‐treated mice in the proliferating areas, relative to controls (Figure 5G).

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PMC11628309

Rodents constitute the main in vivo models, which account for 85% of animal studies.

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PMC10813895

In luminal A BC-subtype cell lines MCF-7 and T47D, ELF5 expression inhibits proliferation, whereas ELF5 promotes cell proliferation in basal-like BC cell lines, suggesting that the role of ELF5 could be cancer subtype-dependent .

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PMC11794568

OCR was measured in control and SK-MEL-2 cells stably overexpressing CRIP1.

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PMC11670954

Caco-2 cells (1 × 10/200 μL) were seeded into the upper chambers of a 24-well Transwell plate (3470, Costar, Corning), and 1.5 mL of fresh medium was added to the lower chambers.

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PMC9429973

Inclusion critheria were age>18years,no other causes of anemia,Hb<10g/dl, ferritin<30ng/ml,TSAT<20%, 1FOBT+/3 with EGDS and PCS normal,no neoplastic hypermenorrhea and/or menometrorrhagia,gastric bleeding(ulcer, gastritis, angiodysplasia),small intestine bleeding(angiodysplasia),Colon bleeding (diverticulitis, angiodys...

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PMC9429973

A majority of low-risk patients (45/63; 71.4%) did not receive letermovir.

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PMC11499955

Furthermore, the levels of overexpressed protein receptors not only differ within the cancer types (10 to 10 receptors per cell) but also vary within the different patient tumour lesions as well as from patient to patient.

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PMC9874064

Specifically, in BEL-7404 cells, the IC50 of NP-Pt-USP1i, NP-Pt and cisplatin are 2.3 μM,7.6 μM, and ＞40 μM, respectively (Fig. 3B).

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PMC11628309

Additionally, other types of fetal serum, such as horse (blue) and calf (cyan), have also been utilized.

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PMC11783017

B, C) ELISA analysis of CCL2 and IL13 expression levels in 143B cells. (

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PMC9429973

The subsequent analysis after patient received at least two dose of the vaccination shows a less severe lymphopenia (P< 0.05) and disease severity O. Gelo, L. Korin, L. Ayala, S. Cranco, E. Babuin, A. Vitriu, P. Ochoa, M. L. Fuente, N. Tartas, M. Alderete, S. Flagel, C. Sosa, M. A. Gazzaneo, M. Zylberman, F. Díaz Couse...

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PMC8903741

Twenty plates per transfection were screened.

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PMC9429973

Although thrombosis can affect any anatomical site, the most frequent sites include intra-abdominal and cerebral veins.

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PMC11632064

Data are relative to MeWo basal conditions.

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PMC10656496

Total RNA was prepared from each osteosarcoma cell line using the mirVana miRNA Isolation Kit (Cat# AM1560, Invitrogen, Thermo Fisher) and RNA-sequencing libraries were prepared using the Nugen Ovation Human FFPE RNA-seq Multiplex System according to the manufacturer’s protocol (Tecan Genomics, Inc, Redwood City, CA).

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PMC11395280

To determine if CCL198-83 disrupted not only receptor internalization but also signaling in CCRF-CEM T-ALL via CCR7, we used Ca mobilization assays.

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PMC10729469

Overall, the results demonstrate that treatment with amyloid β-specific TCRAβ-Tregs improves memory outcomes in APP/PS1 mice compared to treatment with polyclonal Tregs.

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PMC11538390

Primer sequences are shown in Supplementary Data 11.

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PMC11344246

Using these data, the largest connected component of this full PPI graph contained 659 genes with 820 edges between them.

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PMC11422150

Additionally, non-lymphocytic Ly6GCD11bF4/80Ly6C cells, so-called inflammatory M1 macrophages, were also significantly suppressed in the hAMSC group (290 ± 55 cells, P = 0.044) than in the untreated SCI group (430 ± 42 cells, Figure 6C).

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PMC11281366

Total cellular RNAs were extracted using RNeasy RNA extraction columns (Qiagen) according to the manufacturer’s instructions.

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PMC11787355

and analgesia (Carprofen, 5 mg/kg s.c.).

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PMC11637276

Data was normalised between the average of the non-targeting (NT) control and NT in the presence of Bafilomycin A1, as a positive control to assess the magnitude of modulation between technical replicates, as in .

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PMC6114978

No additive effect of adding 5-azacytidine and trichostatin-A was identified in the sarcoma cell lines. (

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PMC9325715

Freundlich model belongs to the oldest and most commonly used isotherm expressions.

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