OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC9429973	For the safety run-in phase, 3 patients were to receive 4 weekly subcutaneous daratumumab injections followed by a 4-week observational period.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "the",...
PMC11766309	The results indicated that the CD274 gene was coexpressed with YKT6.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "results", "indicated", "that", "the", "CD274", "gene", "was", "coexpressed", "...
PMC9111184	Trypsin, Dulbecco's modiﬁed Eagle medium (DMEM), glutamine, Pen-Strep (penicillin and streptomycin mixture), Phosphate-Buffered Saline (PBS) and fetal bovine serum (FBS) were bought from Lonza (Verviers, Belgium), 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) from VWR International, m-coumaric acid...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8956657	Further information on research design is available in the Nature Research Reporting Summary linked to this article.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Further", "information", "on", "research", "desig...
PMC10198699	South Africa’s common law—Roman-Dutch law—is a flexible system that develops with the times.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "South", "Africa", "’s", "common", "law...
PMC11790971	Previously, our lab developed simultaneous label-free autofluorescence multiharmonic (SLAM) microscopy, which allows simultaneous collection of signals from four imaging modalities: two-photon fluorescence (2PF), three-photon fluorescence (3PF), second-harmonic generation (SHG), and third-harmonic generation (THG).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7305184	This presentation allows easier comparison between CTRL and EP and between CTRL + EP and EP group at the same electric field and additionally we can compare different generations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11106977	OA is a prevalent and chronic joint disease that causes progressive cartilage degradation, subchondral bone remodeling, bone marrow lesions, meniscal damage, and synovitis .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11507371	Traditionally associated with inflammation and cell survival, NF-κB has a key role in therapy-resistant cancer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Traditionally", "associated", "with", "inflammation", "and",...
PMC11544122	No. 00-4555-56), counted, and 500,000 cells were resuspended in 4 mL of PBS containing 0.1% w/v BSA (PBS-BSA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11206251	Finally, the PEIM possibly downregulated the expression of TLR4, MyD88, p-NF-κBp65, TNF-α, IL-1β, INOS, IL-6, JAK2, STAT3, CyclinD1, CDK4, MDM2, and Bcl-2, and upregulated the expression of P53, P21, Bax, Cytochrome-C, Caspase-9, and Caspase-3 in HepG2 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Agreement for the SQ between doctors and nurses was moderate (kappa 0.41).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Agreement", "for", "the", "SQ", "between", "doctors", "and", "nu...
PMC11352311	A PPI network was constructed, and the degree of interaction among the intersecting genes was analyzed, leading to the identification of seven core target genes (degree ≥ 10): GAPDH, TNF, GSK3B, CCND1, MCL1, IL2, and CDK2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9739791	An alternative approach to photoreduction of Pt(IV) prodrugs was shown by Mazzei et al. .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "An", "alternative", "approach", "to", "photoreduction", "of", ...
PMC11641532	All in vitro and in vivo experiments were performed in triplicate, and data are presented as mean ± standard error of the mean (SEM) using GraphPad Prism 10 (GraphPad, prism software, v10.2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Consistently, NAC prophylaxis gradually improved BM ECs and CD34+ cells in Group A, whereas reduced their ROS levels post-HSCT.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Consistently", ...
PMC10213179	The complex was allowed to associate and dissociate for 120 and 150 s, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "complex", "was", "allowed", "to", "associate", "and"...
PMC11481779	Multiple neural network architectures have been proposed to face this problem in computer vision - Generative Adversarial Network being a prime example.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Multiple", "...
PMC3730428	Under certain conditions Complex II can induce cell death through an non-apoptotic, programmed necrosis pathway, which is dependent on RIPK1 and 3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11240571	The pellets were washed with PBS, ultracentrifuged, and resuspended in 10 μL PBS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "pellets", "were", "washed", "with", "PBS", ",", ...
PMC11727145	Exudates are fluids produced by the body in response to tissue damage.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Exudates", "are", "fluids", "produced", "by", "the", "body", "in", "response", ...
PMC11064533	Enteroaggregative E. coli (EAEC) display an aggregative adherence pattern or localized adhesion due to the autoagglutination of bacterial cells shown by the stacked-brick configuration, which occurs on the host cell surface usually in the presence of D-mannose.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Early stage (ISS1/R-ISS1) was more frequent in the non-UHR group (p<0.05); 1 line treatment, including autologous transplantation (ASCT), and second line treatment were well balanced between groups (p<0.05); 66% of patients overall, received triplet/quadruplet combinations and 29% underwent ASCT upfront.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11806818	Figure 3A shows the preparation process of h-JHNzyme and the principle of SERS detection using h-JHNzyme.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Figure", "3A", "shows", "the", "preparation", "process...
PMC11640555	Treatment of CX-4945 at the lower dose of 50 mg/kg did not significantly reduce immunopositivity for Ki-67 marker (Figure 9B,B1 and score Figure 9D), whereas the higher dose of 100 mg/kg of CX-4945 demonstrated a notable capacity to reduce the number of cells positive for the proliferative marker Ki-67 (Figure 9C,C1 an...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9351137	Pontin, Reptin, and Tip60, subunits of SRCAP (Snf-2-related CREB-binding protein activator protein) p400/Tip60 chromatin remodeling complexes , as well as the INO80 remodeler, were shown to relocate to mitotic apparatus and suggested to play direct roles during cell division in human cells [24–29].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10728535	Using the specialized inhibitors of this pathway is an efficient and safe strategy to overcome drug resistance without affecting the normal cell performance in the cancer tissue.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11779605	The specific targets that have been evaluated fall into categories of proteins, microRNAs, long non-coding RNAs including circular RNAs, biomarkers of stem cells, epithelial-to-mesenchymal transition or DNA repair, DNA mutations or methylation patterns, histone acetylation patterns, and extrachromosomal circular DNAs (...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11727062	Yu et al. 2020).	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Yu", "et", "al.", "2020", ")", "." ] } ]
PMC11129910	Additionally, we expressed other oncogenes, namely, H-RASV12G and IGF1-R in HMEC 5.6 RAB25- cells, and checked the expression level of these oncogenes at the protein level (Figures 2(c) and 2(d)).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11591038	Notably, HIF-1α is induced in M1 macrophage polarization, whereas HIF-2α is induced during an M2 response.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notably", ",", "HIF-1α", "is", "induce...
PMC11705862	Subsequently, we confirmed the presence of IRIS-1 and 2 at the protein level in undifferentiated SH-SY5Y cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Subsequently", ",", "we", "confirme...
PMC11738017	At time 0, the cells were seeded at 1 × 10 cells per mL with or without GSI at a dose of 200 nM. The supernatant was collected at the respective time points and the sBCMA levels analyzed by enzyme-linked immunosorbent assay.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3203927	With the exception of a few samples, most of the five values represented in all the data sets (Figure 1, bottom), are in agreement.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7504302	Table 2 lists the most recent MPM studies on ncRNAs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Table", "2", "lists", "the", "most", "recent", "MPM", "studies", "on", "ncRNAs", "." ]...
PMC9429973	The most common grade 3 or 4 adverse events were infection (n=8, 21.1%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "most", "common", "grade", "3", "or",...
PMC9429973	Methods: Eligible patients were ≥18 y with R/R LBCL.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Methods", ":", "Eligible", "patients", "were", "≥18", "y", "with", "R/R", "LBCL", "." ...
PMC9429973	Given the frequent association between this deficit and AL, abdominal fat pad biopsy was performed, which was negative for Congo red staining.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11534377	Cells treated with 5-Aza exhibited major morphological differences, characterized by disorganized actin filaments, irregularly shaped nuclei, and more scattered mitochondrial staining, indicating disrupted metabolic activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6835428	The first is the biological/anatomical features of OC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "first", "is", "the", "biological/anatomical", "features", "of", "OC", "." ] } ]
PMC11748618	Haplotypes (N = 3) that had at least one GWAS significant variant were selected for statistical modelling.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Haplotypes", "(", "N", "=", ...
PMC11763111	These findings provide a solid foundation for future preclinical investigations and clinical trials to optimize this therapeutic approach.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "findings", "provide", "a", "s...
PMC11001582	Statistical methods were used to predetermine sample sizes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "methods", "were", "used", "to", "predetermine", "sample", "sizes", "." ] } ]
PMC9429973	However, 2-day pre-treatment with epigenetic drugs (Vorinostat, Tazemetostat, Valemostat and Azacytidine) and 7-day pre-treatment with Tazemetostat + Azacytidine had no effect on Ven sensitivity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11367146	The visualisation of the enriched GO categories was done using an SR plot in the form of a bar graph.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "visualisation", "of",...
PMC9822769	Immobilized artificial membrane (IAM) chromatography is a complementary technique for evaluating the interaction of a drug with the cellular membrane.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Immobilized", ...
PMC11627060	Previous studies have indicated that AIFs can cause cell death through caspase-independent mechanisms .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Previous", "studies", "have", "indicated", "that", "AIFs", "can", "cause", ...
PMC9352806	Twenty nematodes in each group were examined per experiment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Twenty", "nematodes", "in", "each", "group", "were", "examined", "per", "experiment", "." ] } ]
PMC11186948	For fractionation LCLs cellular pellets were split equally in two recipients: for total lysate (Total) and cytoplasm/nuclei fraction.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "fractionation", ...
PMC8753818	Findings represented the analysis of 3 experiments and n was 3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Findings", "represented", "the", "analysis", "of", "3", "experiments", "and", "n", "w...
PMC8164677	All other solvents or chemicals used in this study were of analytical grade.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "other", "solvents", "or", "chemicals", "used", "in", "this", "...
PMC10899471	HT-1080 cells were harvested 48 h after transfection using Lipofectamine 3000 (Invitrogen).	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HT-1080", "cells", "were", "harvested", "48", "h", "after", ...
PMC11678841	This resulted in a significant reduction in the secretion levels of the inflammatory cytokines IL-6 and IL-1α, as well as IL-1β.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "resu...
PMC11758416	n = 6 (B) Comparison of cell death of L cells pre-incubated with anti-CD3 OKT3 clone vs. SK7 clone following incubation with CD8 T cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "...
PMC10142392	PCL-based micelles have multiple advantages, including improved permeation and retention (EPR), increased blood circulation time, and increased endocytosis due to surface modification.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10551595	It was reported that small molecules targeting L1/S3 binding pocket had the ability to reactivate P53R175H.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "was", "reported", "that", "small", "molecules", ...
PMC11615101	The confocal microscopy image shows TLR-2 expression (yellow) and nucleus (blue) in RAFLS. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "confocal", "microscopy", "image", ...
PMC9243326	Gene Ontology (GO) annotation was performed using the Blast2GO software with the Nr annotation results for the unigenes (Conesa et al., 2005).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11507371	Understanding the specific molecular pathways governing NF-κB’s differential roles is essential to maximise efficacy while minimising adverse effects of therapeutic interventions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Understanding", ...
PMC11802855	Activation level of the “Osteoclast signaling” (H) and “B-cell proliferation” (I) pathway in various MM subsets.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC8633974	Agarose gel electrophoresis of PCR product showed in both U1 cells (e) and JLat cells (f) full-length HIV was present in untreated cells but not treated cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC7351993	Details of each component are as follows.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Details", "of", "each", "component", "are", "as", "follows", "." ] } ]
PMC11765678	For ABCG2, X-ray crystal structures 6VXH (Imanitib), 6VXI (Mitoxantrone), 6VXJ (SN-38), 7NEQ (Tariquidar), 7NEZ (Topotecan), 7NFD (Mitoxantrone), 7OJ8 (Estrone-3-sulfate), 7OJH (Topotecan, the protein was in turnover state 1), and 7OJI (Topotecan, the protein was in turnover state 2) were used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9268620	At this level, the chromatin had already collapsed into two or more spherical masses.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "this", "level", ",", "the", "chromatin", "had", ...
PMC2614416	Overwhelming preponderance of oxidoreductases in the liver is additionally supported by the isomerase DAGs: nearly all the reactions described in the normal liver isomerase DAG are oxidoreductase isomerization reactions, whereas only one of the three child nodes in the HepG2 isomerase DAG is oxidoreductase.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10772747	At a more advanced level, P53 activation can influence the expression of various genes involved in cell proliferation and tumor formation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "a", ...
PMC8759873	We transfected the VHL gene into renal cancer cell line 786-0, using the RT-PCR method at the transcription level.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": ...
PMC11637276	Box and whisker plots represent 5–95 percentile, + represents the mean; dots are <5% and >95%; N = 3 independent experiments. ****	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8806312	Relationship between the level of T cells CD4 memory activated cells and metastasis. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Relationship", "between", "the", "level", "of", "T", "cells", "C...
PMC9429973	In addition to increased anti-tumor T-cell activity, NX-1607 also potentiates the anti-tumor cytotoxic and antibody-dependent cellular cytotoxicity (ADCC) activity of NK cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11621493	Heat maps displaying the z-score of PE, PPE, EtherPE, EtherPC, HexCER, CER, and SM subspecies were labeled by the number of C-atoms in fatty acids and the total number of double bonds.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11755519	What brings more attention and potential implications is the fact that cancer cells secrete more EVs than non-malignant cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "What", "brings", "more", "attenti...
PMC11711935	Melasma is a common acquired symmetrical hyperpigmentation of melanin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Melasma", "is", "a", "common", "acquired", "symmetrical", "hyperpigmentation", "of", "melanin", "." ] ...
PMC11683130	Serpin is a single chain protein, consisting of 350 ~ 400 amino acids.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Serpin", "is", "a", "single", "chain", "protein", ",", "consisti...
PMC10772747	The obtained filtrate was evaporated using a rotary evaporator.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "obtained", "filtrate", "was", "evaporated", "using", "a", "rotary", "evaporator", "." ] } ]
PMC11697065	Flow rate was set to 0.5 ml/min and injection volume was adjusted to load 40 µg on the column.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Flow", "rate", "was", "set", ...
PMC11451940	Chemically, it contains a 1,4-naphthoquinone moiety, similar to the fat-soluble vitamin K (see Scheme 1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Chemically", ",", "it", "contains...
PMC11725127	The appropriate temperatures were determined by preliminary CETSA experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "appropriate", "temperatures", "were", "determined", "by", "preliminary", "CETSA", "experiments", "."...
PMC11750696	These together indicates that targeting UPR might stand as a viable approach for the therapy of RA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "together", "indicates", "that", "targeti...
PMC11286266	Top panel: Two-dimensional contour plots of BiP::sfGFP and XBP1s::mCherry signals in untreated cells (UT, grey) and cells treated with the endoplasmic reticulum (ER) stressors 2-deoxy-D-glucose (2DG, 4 mM, blue), tunicamycin (Tm, 2.5 µg/ml, orange), or thapsigargin (Tg, 0.5 µM, purple) over a short (6 hr) and long peri...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11738017	∗∗∗∗P ≤ .0001. (	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "∗∗∗∗P", "≤", ".0001", ".", "(" ] } ]
PMC6182045	The consensus sequence was trimmed to match the known amino acids in TZ97008 (V42–A525, HXB2 reference numbering).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "consensus", "sequence...
PMC9429973	Methods: We performed a retrospective study involving young patients with CLL (≤ 65 years old),in the clinical hematology department of Aziza Othmana Hospital,in Tunisia between 2013 and 2020.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	In a single case OGM was able to detect a high-risk aberration which was missed by CCG.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "a", "single", "case", "OGM", "was", ...
PMC9635307	On the other hand, we have observed that an agonistic monoclonal antibody (mAb) or the natural ligands bound to the extracellular N-domain of CEACAM1 can suppress animal models of IBD as found in one of our previous studies .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11795610	Immediately after, we further analyzed cell cycle distribution.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Immediately", "after", ",", "we", "further", "analyzed", "cell", "cycle", "distribution", "." ] } ]
PMC11758416	Centrifuge at approximately 450 × g for 5 min at 4°C to pellet cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Centrifuge", "at", "approximately", "450", "×", "g", ...
PMC11655536	The intracellular acidification and enhanced lysosome biogenesis were also observed in primary MM cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "intracellular", "acidification", "and", "enhanced", "lysosome", ...
PMC11545868	However, apoptosis, one of the programs imprinted on cells, is becoming an important concept in controlling cancer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "apoptosis", ...
PMC9429973	Methods: A total of 148 Fanconi anemia patients from 140 families were diagnosed by clinical phenotype, family history, chromosome breakage test induced by mitomycin C, Single cell gel electrophoresis experiment, targeted - sequence, whole exon sequencing, and MLPA method from October 2003 to October 2021.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	It has an excellent prognosis with the excision of the affected ganglion.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "has", "an", "excellent", "prognosis", "with", "the", "excision", "of", ...
PMC9429973	The other syndromes lymphoproliferative or myeloproliferative were not found in our series.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "other", "syndromes", "lymphoproliferative", "or", "myeloproliferative", "were", ...
PMC10545062	This was implemented to be anticipatory and predictive rather than reactive.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "was", "implemented", "to", "be", "anticipatory", "and", "predictive", "rather", ...
PMC11640476	This SOP can be useful in testing new biocompatible materials, performing drug screening, evaluating environmental toxins, and studying cellular responses to various treatments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11015054	Analysis of METTL5 expression in HCC using immunohistochemistry and TCGA‐LIHC data.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Analysis", "of", "METTL5", "expression", "in", "HCC", "using", "immunohistochemistry", "and...
PMC11687663	We detected the peaks in LC-MS chromatograms by utilizing mass spectra m/z databases including Mass Bank of Europe (https://massbank.eu/MassBank/) and National Library of Medicine (https://www.nlm.nih.gov/), as well as relevant literature [24–27].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The novel monoclonal anti-CD20 antibody obinutuzumab in combination with chemotherapy has been widely accepted as the first choice in front line treatment of FL.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11596967	Ddes-P3 is an AOP composed of 10 amino acids with an MW of 1106 Da (Table 1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ddes-P3", "is", "an", "AOP", ...
PMC11298021	The expression level of mTOR and S6Kb1 genes in Jurkat cells transfected with miR-3182 indicated a considerable decrease compared to non-transfected cells ( *** P<0.001). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11742864	Further studies revealed that prostaglandin (PG) E2 boosted NSCLC cell proliferation via upregulating the AKT/protein kinase B pathway, while PGE3 suppressed this pathway.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC9429973

For the safety run-in phase, 3 patients were to receive 4 weekly subcutaneous daratumumab injections followed by a 4-week observational period.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "the",...

PMC11766309

The results indicated that the CD274 gene was coexpressed with YKT6.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "results", "indicated", "that", "the", "CD274", "gene", "was", "coexpressed", "...

PMC9111184

Trypsin, Dulbecco's modiﬁed Eagle medium (DMEM), glutamine, Pen-Strep (penicillin and streptomycin mixture), Phosphate-Buffered Saline (PBS) and fetal bovine serum (FBS) were bought from Lonza (Verviers, Belgium), 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) from VWR International, m-coumaric acid...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8956657

Further information on research design is available in the Nature Research Reporting Summary linked to this article.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Further", "information", "on", "research", "desig...

PMC10198699

South Africa’s common law—Roman-Dutch law—is a flexible system that develops with the times.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "South", "Africa", "’s", "common", "law...

PMC11790971

Previously, our lab developed simultaneous label-free autofluorescence multiharmonic (SLAM) microscopy, which allows simultaneous collection of signals from four imaging modalities: two-photon fluorescence (2PF), three-photon fluorescence (3PF), second-harmonic generation (SHG), and third-harmonic generation (THG).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7305184

This presentation allows easier comparison between CTRL and EP and between CTRL + EP and EP group at the same electric field and additionally we can compare different generations.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11106977

OA is a prevalent and chronic joint disease that causes progressive cartilage degradation, subchondral bone remodeling, bone marrow lesions, meniscal damage, and synovitis .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11507371

Traditionally associated with inflammation and cell survival, NF-κB has a key role in therapy-resistant cancer.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Traditionally", "associated", "with", "inflammation", "and",...

PMC11544122

No. 00-4555-56), counted, and 500,000 cells were resuspended in 4 mL of PBS containing 0.1% w/v BSA (PBS-BSA).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11206251

Finally, the PEIM possibly downregulated the expression of TLR4, MyD88, p-NF-κBp65, TNF-α, IL-1β, INOS, IL-6, JAK2, STAT3, CyclinD1, CDK4, MDM2, and Bcl-2, and upregulated the expression of P53, P21, Bax, Cytochrome-C, Caspase-9, and Caspase-3 in HepG2 cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Agreement for the SQ between doctors and nurses was moderate (kappa 0.41).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Agreement", "for", "the", "SQ", "between", "doctors", "and", "nu...

PMC11352311

A PPI network was constructed, and the degree of interaction among the intersecting genes was analyzed, leading to the identification of seven core target genes (degree ≥ 10): GAPDH, TNF, GSK3B, CCND1, MCL1, IL2, and CDK2.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9739791

An alternative approach to photoreduction of Pt(IV) prodrugs was shown by Mazzei et al. .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "An", "alternative", "approach", "to", "photoreduction", "of", ...

PMC11641532

All in vitro and in vivo experiments were performed in triplicate, and data are presented as mean ± standard error of the mean (SEM) using GraphPad Prism 10 (GraphPad, prism software, v10.2).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Consistently, NAC prophylaxis gradually improved BM ECs and CD34+ cells in Group A, whereas reduced their ROS levels post-HSCT.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Consistently", ...

PMC10213179

The complex was allowed to associate and dissociate for 120 and 150 s, respectively.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "complex", "was", "allowed", "to", "associate", "and"...

PMC11481779

Multiple neural network architectures have been proposed to face this problem in computer vision - Generative Adversarial Network being a prime example.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Multiple", "...

PMC3730428

Under certain conditions Complex II can induce cell death through an non-apoptotic, programmed necrosis pathway, which is dependent on RIPK1 and 3.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11240571

The pellets were washed with PBS, ultracentrifuged, and resuspended in 10 μL PBS.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "pellets", "were", "washed", "with", "PBS", ",", ...

PMC11727145

Exudates are fluids produced by the body in response to tissue damage.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Exudates", "are", "fluids", "produced", "by", "the", "body", "in", "response", ...

PMC11064533

Enteroaggregative E. coli (EAEC) display an aggregative adherence pattern or localized adhesion due to the autoagglutination of bacterial cells shown by the stacked-brick configuration, which occurs on the host cell surface usually in the presence of D-mannose.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Early stage (ISS1/R-ISS1) was more frequent in the non-UHR group (p<0.05); 1 line treatment, including autologous transplantation (ASCT), and second line treatment were well balanced between groups (p<0.05); 66% of patients overall, received triplet/quadruplet combinations and 29% underwent ASCT upfront.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11806818

Figure 3A shows the preparation process of h-JHNzyme and the principle of SERS detection using h-JHNzyme.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Figure", "3A", "shows", "the", "preparation", "process...

PMC11640555

Treatment of CX-4945 at the lower dose of 50 mg/kg did not significantly reduce immunopositivity for Ki-67 marker (Figure 9B,B1 and score Figure 9D), whereas the higher dose of 100 mg/kg of CX-4945 demonstrated a notable capacity to reduce the number of cells positive for the proliferative marker Ki-67 (Figure 9C,C1 an...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9351137

Pontin, Reptin, and Tip60, subunits of SRCAP (Snf-2-related CREB-binding protein activator protein) p400/Tip60 chromatin remodeling complexes , as well as the INO80 remodeler, were shown to relocate to mitotic apparatus and suggested to play direct roles during cell division in human cells [24–29].

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PMC10728535

Using the specialized inhibitors of this pathway is an efficient and safe strategy to overcome drug resistance without affecting the normal cell performance in the cancer tissue.

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PMC11779605

The specific targets that have been evaluated fall into categories of proteins, microRNAs, long non-coding RNAs including circular RNAs, biomarkers of stem cells, epithelial-to-mesenchymal transition or DNA repair, DNA mutations or methylation patterns, histone acetylation patterns, and extrachromosomal circular DNAs (...

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PMC11727062

Yu et al. 2020).

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PMC11129910

Additionally, we expressed other oncogenes, namely, H-RASV12G and IGF1-R in HMEC 5.6 RAB25- cells, and checked the expression level of these oncogenes at the protein level (Figures 2(c) and 2(d)).

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PMC11591038

Notably, HIF-1α is induced in M1 macrophage polarization, whereas HIF-2α is induced during an M2 response.

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PMC11705862

Subsequently, we confirmed the presence of IRIS-1 and 2 at the protein level in undifferentiated SH-SY5Y cells.

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PMC11738017

At time 0, the cells were seeded at 1 × 10 cells per mL with or without GSI at a dose of 200 nM. The supernatant was collected at the respective time points and the sBCMA levels analyzed by enzyme-linked immunosorbent assay.

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PMC3203927

With the exception of a few samples, most of the five values represented in all the data sets (Figure 1, bottom), are in agreement.

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PMC7504302

Table 2 lists the most recent MPM studies on ncRNAs.

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PMC9429973

The most common grade 3 or 4 adverse events were infection (n=8, 21.1%).

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PMC9429973

Methods: Eligible patients were ≥18 y with R/R LBCL.

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PMC9429973

Given the frequent association between this deficit and AL, abdominal fat pad biopsy was performed, which was negative for Congo red staining.

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PMC11534377

Cells treated with 5-Aza exhibited major morphological differences, characterized by disorganized actin filaments, irregularly shaped nuclei, and more scattered mitochondrial staining, indicating disrupted metabolic activity.

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PMC6835428

The first is the biological/anatomical features of OC.

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PMC11748618

Haplotypes (N = 3) that had at least one GWAS significant variant were selected for statistical modelling.

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PMC11763111

These findings provide a solid foundation for future preclinical investigations and clinical trials to optimize this therapeutic approach.

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PMC11001582

Statistical methods were used to predetermine sample sizes.

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PMC9429973

However, 2-day pre-treatment with epigenetic drugs (Vorinostat, Tazemetostat, Valemostat and Azacytidine) and 7-day pre-treatment with Tazemetostat + Azacytidine had no effect on Ven sensitivity.

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PMC11367146

The visualisation of the enriched GO categories was done using an SR plot in the form of a bar graph.

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PMC9822769

Immobilized artificial membrane (IAM) chromatography is a complementary technique for evaluating the interaction of a drug with the cellular membrane.

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PMC11627060

Previous studies have indicated that AIFs can cause cell death through caspase-independent mechanisms .

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PMC9352806

Twenty nematodes in each group were examined per experiment.

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PMC11186948

For fractionation LCLs cellular pellets were split equally in two recipients: for total lysate (Total) and cytoplasm/nuclei fraction.

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PMC8753818

Findings represented the analysis of 3 experiments and n was 3.

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PMC8164677

All other solvents or chemicals used in this study were of analytical grade.

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PMC10899471

HT-1080 cells were harvested 48 h after transfection using Lipofectamine 3000 (Invitrogen).

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PMC11678841

This resulted in a significant reduction in the secretion levels of the inflammatory cytokines IL-6 and IL-1α, as well as IL-1β.

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PMC11758416

n = 6 (B) Comparison of cell death of L cells pre-incubated with anti-CD3 OKT3 clone vs. SK7 clone following incubation with CD8 T cells.

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PMC10142392

PCL-based micelles have multiple advantages, including improved permeation and retention (EPR), increased blood circulation time, and increased endocytosis due to surface modification.

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PMC10551595

It was reported that small molecules targeting L1/S3 binding pocket had the ability to reactivate P53R175H.

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PMC11615101

The confocal microscopy image shows TLR-2 expression (yellow) and nucleus (blue) in RAFLS. (

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PMC9243326

Gene Ontology (GO) annotation was performed using the Blast2GO software with the Nr annotation results for the unigenes (Conesa et al., 2005).

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PMC11507371

Understanding the specific molecular pathways governing NF-κB’s differential roles is essential to maximise efficacy while minimising adverse effects of therapeutic interventions.

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PMC11802855

Activation level of the “Osteoclast signaling” (H) and “B-cell proliferation” (I) pathway in various MM subsets.

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PMC8633974

Agarose gel electrophoresis of PCR product showed in both U1 cells (e) and JLat cells (f) full-length HIV was present in untreated cells but not treated cells.

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PMC7351993

Details of each component are as follows.

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PMC11765678

For ABCG2, X-ray crystal structures 6VXH (Imanitib), 6VXI (Mitoxantrone), 6VXJ (SN-38), 7NEQ (Tariquidar), 7NEZ (Topotecan), 7NFD (Mitoxantrone), 7OJ8 (Estrone-3-sulfate), 7OJH (Topotecan, the protein was in turnover state 1), and 7OJI (Topotecan, the protein was in turnover state 2) were used.

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PMC9268620

At this level, the chromatin had already collapsed into two or more spherical masses.

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PMC2614416

Overwhelming preponderance of oxidoreductases in the liver is additionally supported by the isomerase DAGs: nearly all the reactions described in the normal liver isomerase DAG are oxidoreductase isomerization reactions, whereas only one of the three child nodes in the HepG2 isomerase DAG is oxidoreductase.

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PMC10772747

At a more advanced level, P53 activation can influence the expression of various genes involved in cell proliferation and tumor formation.

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PMC8759873

We transfected the VHL gene into renal cancer cell line 786-0, using the RT-PCR method at the transcription level.

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PMC11637276

Box and whisker plots represent 5–95 percentile, + represents the mean; dots are <5% and >95%; N = 3 independent experiments. ****

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PMC8806312

Relationship between the level of T cells CD4 memory activated cells and metastasis. (

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PMC9429973

In addition to increased anti-tumor T-cell activity, NX-1607 also potentiates the anti-tumor cytotoxic and antibody-dependent cellular cytotoxicity (ADCC) activity of NK cells.

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PMC11621493

Heat maps displaying the z-score of PE, PPE, EtherPE, EtherPC, HexCER, CER, and SM subspecies were labeled by the number of C-atoms in fatty acids and the total number of double bonds.

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PMC11755519

What brings more attention and potential implications is the fact that cancer cells secrete more EVs than non-malignant cells.

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PMC11711935

Melasma is a common acquired symmetrical hyperpigmentation of melanin.

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PMC11683130

Serpin is a single chain protein, consisting of 350 ~ 400 amino acids.

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PMC10772747

The obtained filtrate was evaporated using a rotary evaporator.

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PMC11697065

Flow rate was set to 0.5 ml/min and injection volume was adjusted to load 40 µg on the column.

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PMC11451940

Chemically, it contains a 1,4-naphthoquinone moiety, similar to the fat-soluble vitamin K (see Scheme 1).

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PMC11725127

The appropriate temperatures were determined by preliminary CETSA experiments.

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PMC11750696

These together indicates that targeting UPR might stand as a viable approach for the therapy of RA.

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PMC11286266

Top panel: Two-dimensional contour plots of BiP::sfGFP and XBP1s::mCherry signals in untreated cells (UT, grey) and cells treated with the endoplasmic reticulum (ER) stressors 2-deoxy-D-glucose (2DG, 4 mM, blue), tunicamycin (Tm, 2.5 µg/ml, orange), or thapsigargin (Tg, 0.5 µM, purple) over a short (6 hr) and long peri...

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PMC11738017

∗∗∗∗P ≤ .0001. (

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PMC6182045

The consensus sequence was trimmed to match the known amino acids in TZ97008 (V42–A525, HXB2 reference numbering).

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PMC9429973

Methods: We performed a retrospective study involving young patients with CLL (≤ 65 years old),in the clinical hematology department of Aziza Othmana Hospital,in Tunisia between 2013 and 2020.

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PMC9429973

In a single case OGM was able to detect a high-risk aberration which was missed by CCG.

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PMC9635307

On the other hand, we have observed that an agonistic monoclonal antibody (mAb) or the natural ligands bound to the extracellular N-domain of CEACAM1 can suppress animal models of IBD as found in one of our previous studies .

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PMC11795610

Immediately after, we further analyzed cell cycle distribution.

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PMC11758416

Centrifuge at approximately 450 × g for 5 min at 4°C to pellet cells.

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PMC11655536

The intracellular acidification and enhanced lysosome biogenesis were also observed in primary MM cells.

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PMC11545868

However, apoptosis, one of the programs imprinted on cells, is becoming an important concept in controlling cancer.

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PMC9429973

Methods: A total of 148 Fanconi anemia patients from 140 families were diagnosed by clinical phenotype, family history, chromosome breakage test induced by mitomycin C, Single cell gel electrophoresis experiment, targeted - sequence, whole exon sequencing, and MLPA method from October 2003 to October 2021.

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PMC9429973

It has an excellent prognosis with the excision of the affected ganglion.

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PMC9429973

The other syndromes lymphoproliferative or myeloproliferative were not found in our series.

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PMC10545062

This was implemented to be anticipatory and predictive rather than reactive.

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PMC11640476

This SOP can be useful in testing new biocompatible materials, performing drug screening, evaluating environmental toxins, and studying cellular responses to various treatments.

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PMC11015054

Analysis of METTL5 expression in HCC using immunohistochemistry and TCGA‐LIHC data.

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PMC11687663

We detected the peaks in LC-MS chromatograms by utilizing mass spectra m/z databases including Mass Bank of Europe (https://massbank.eu/MassBank/) and National Library of Medicine (https://www.nlm.nih.gov/), as well as relevant literature [24–27].

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PMC9429973

The novel monoclonal anti-CD20 antibody obinutuzumab in combination with chemotherapy has been widely accepted as the first choice in front line treatment of FL.

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PMC11596967

Ddes-P3 is an AOP composed of 10 amino acids with an MW of 1106 Da (Table 1).

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PMC11298021

The expression level of mTOR and S6Kb1 genes in Jurkat cells transfected with miR-3182 indicated a considerable decrease compared to non-transfected cells ( *** P<0.001). (

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PMC11742864

Further studies revealed that prostaglandin (PG) E2 boosted NSCLC cell proliferation via upregulating the AKT/protein kinase B pathway, while PGE3 suppressed this pathway.

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