OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11591052	The reference gene selected was β-actin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "reference", "gene", "selected", "was", "β-actin", "." ] } ]
PMC11792888	All signals from proteins of interest were normalized based on the (-tubulin or (-actin signals.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "signals", "from", "proteins", "of", ...
PMC10976516	So it is tempting to use immune cells in such a way that their natural features can be combined with a role as OV carrier cells and stimulate an even more robust antitumor response.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Most adverse events (AEs) were of grade 1 to 2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Most", "adverse", "events", "(", "AEs", ")", "were", "of", "grade", "1", ...
PMC8623816	A sequence search with BLASTP suggested that this protein was most closely related to the RdRp of some viruses in the family Partitiviridae, such as the Penicillium aurantiogriseum partiti-like virus .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10772747	The results in Figure 5 (C and D) showed that the cell cycle distribution in the DOX and 1,4-naphthoquinone treatment groups did not significantly differ from the untreated control group (P>0.0001).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9684669	In contrast, CREB1 phosphorylation remained lower in the combined treatment, indicating that CAMK2 inhibitors repressed the CAMK2/CREB1 pathway ( Figures 6E.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC11349530	Cancer cells are capable of producing various growth factors such as VEGF, TGF-β, PDGF, etc.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cancer", "cells", "are", "capable", "o...
PMC6684588	In addition, activin A and activin B are implicated as endogenous inhibitors of muscle growth that act synergistically with myostatin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ...
PMC9429973	Methods: Hem/oncs participated in a 22-minute segmented online multi-media activity consisting of videos portraying realistic physician–patient interactions followed by expert commentaries.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9221284	This result validates the capability of the 9E10 antibody used against the C-terminal region to detect c-Myc protein isoforms with an unaltered C-terminal region, and to some extent the identity of the bands that were described in Figure 2A,B. Of note, c-Myc1 (67 kDa) was undetectable in both lymph nodes (this work) an...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS) were graded by ASBMT, AE according to CTCAE 5.0.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9621239	Sn at each amino acid site in genotype-C and genotype-D clones. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Sn", "at", "each", "amino", "acid", "site", "in", "genotype-C", "and", "ge...
PMC7294030	Fluorouracil (5-FU), the positive control, also significantly increased the proportion of cells in the G0/G1 phase from 74.7 ± 1.97 % to 81.07 ± 1.66 % as compared to negative controls (Figure 3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10568263	Cancer is a leading global health issue with increasing incidence and mortality every year, impacting all communities worldwide regardless of religion, race, or age.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10938336	After 24 h, the cells were treated with the compounds at concentrations between 1.875 and 30.0 μM. MTT (3-(4,5-dimethylthiazol-2yl)-2,5-diphenyltetrazolium bromide) solution (201 of 0.5 mg/mL) was added to each well after 24 h of incubation, with the incubation continuing for additional 4 h at 37 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Patients will be referred early to an allograft of bone marrow,thus avoiding the fatal consequences of sepsis due to neutropenia or hemorrhage on severe thrombocytopenia M. Bektaş, A. E. Eşkazan, T. O. Tiryaki, R. Mullai, T. Elverdi, A. Salihoğlu, M. Tiribelli, M. C. Ar, S. Öngören, Z. Başlar, M. Nalçaci, T. Soysal Dep...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11727907	This study aims to investigate the effect of IGF-1 on PKM2 modulation of RPE cells and whether co-treatment with klotho may preserve it.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", ...
PMC10698968	MF-R 3 and 143B cells were seeded at 2*10 cells/cm density in technical quintuplicate into 96-well plates and cultured for 7 days at standard conditions.	[ { "tags": [ "B-CellLine", "I-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC9429973	Reasons for FEDR discontinuation (D/C) in >1 pt were lack of efficacy (n=5), AEs (n=4), disease progression (n=2), pt decision (n=2), and to undergo transplant (n=2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11755624	lncRNAs regulate pivotal signaling pathways linked to immune responses and inflammatory processes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "lncRNAs", "regulate", "pivotal", "signaling", "pathways", "linked", "to", "immune", ...
PMC5173112	of three independent experiments, each performed in triplicate. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "of", "three", "independent", "experiments", ",", "each", "performed", "in", "triplicate", ".", ...
PMC11758416	Periodically stain the CD32-expressing L cells for CD32 to ensure expression is not lost.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Periodically", "stain", "the", "CD32-expressing", "L", "cells", "for",...
PMC9429973	The majority of cases (90.9%) showed expression of MYC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "majority", "of", "cases", "(", "90.9", "%", ")", "showed", "express...
PMC9429973	Functional experiments were performed to depict the role of a BMP2-induced subset of γδ T cells in the anti-AML activity of effector γδ T cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11489351	An FDR < 0.05 cut-off was applied to our RNA-Seq analysis for pathway analysis and determination of targets for biochemical validation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "An", "FDR", "<", ...
PMC9429973	In DLBCL, the most frequent mutation was a novel C>T mutation at position 4 (g.4C>T) found in 8.4% of cases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	We hypothesized that adding parsaclisib may improve clinical benefit with a manageable safety profile in this pt population.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "hypothesized", "that", "adding", ...
PMC9878562	Conversely, ACKR3 was expressed only on a fraction of VAL-wt (10-18%), despite their clonal nature and continuous mRNA levels of the receptor (32).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11587606	Statistical analysis was performed by GraphPad Prism 5.0 (GraphPad Software, CA, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "analysis", "was", "performed", "by", "G...
PMC11248911	When compared to sorafenib (pIC50 = 7.4) as the reference drug, derivative 8 inhibited VEGFR2 at pIC50 value of 6.7.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "When", ...
PMC8389560	In this work, it was shown for the first time that the generation of Ca signals in A-172 cells occurs in response to the application of various concentrations of selenium nanoparticles.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", ...
PMC11770199	Human colon cancer cells of HCT8 were transfected with PCDH-GFP or PCDH-GFP-p14.	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Human", "colon", "cancer", "cells", "of", "HCT8", "were", "transfected", ...
PMC11566417	Neutrophils collected from 3 cows were tested against each treatment and the plates were incubated for 1 h at 37°C before inserts were removed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11621493	Ct values for Pla2g4d are shown above each bar.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ct", "values", "for", "Pla2g4d", "are", "shown", "above", "each", "bar", "." ] } ]
PMC5311252	Total LC-MS run time was 74 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Total", "LC-MS", "run", "time", "was", "74", "min", "." ] } ]
PMC11267830	Furthermore, splicing events for EZH2 and THOC1 in primary cells posttreatment were confirmed, consistent with the cell line outcomes (Fig. 9c).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11095939	B, F, J, N) Statistical analysis of the cell cycle distribution. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "B", ",", "F", ",", "J", ",", "N", ")", ...
PMC11361748	Collectively, these results indicate a role for CXCR2 and CXCR3 ligands and their receptors in mediating the keratinocyte- and K17-dependent recruitment of neutrophils, in both mouse skin in vivo and human keratinocyte cultures ex vivo.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10748106	The plot of Figure 11 shows that the mathematical model has an acceptable descriptive ability, considering the limited number of compounds employed for the model.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9479186	Inoculation was performed aseptically.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Inoculation", "was", "performed", "aseptically", "." ] } ]
PMC9046263	A single DNA band was localized around 170–190 bp, excised and DNA was extracted using the QIAquick gel extraction kit (Qiagen, 28,704) according to manufacturer’s protocol.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11481779	We have calculated pearson correlation of the insulation scores for all heatmaps (we have filtered out the ones that in real Hi-C data are starting/ending with zeros, as well as the ones that contain more than 5% of zero values).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10698968	Before treatment, spheroids’ formation was allowed for 5 days.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Before", "treatment", ",", "spheroids", "’", "formation", "was", "allowed", "for", "5...
PMC9429973	During the entire period of the study 5 deaths were registered: 3 were related to progression, 2 – because of COVID-19.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "During"...
PMC11683240	Blue line: chromatogram from the chromatographic fractionation process, gray bars = screening result, green bars: screening results that were considered as hits and or subjected to further chromatographic fractionation).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Image: Summary/Conclusion: Our results show that Hybridization capture NGS is a good technique to detect KMT2A-PTDs, with a better sensibility than PCR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11297139	Scale bar: 5 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", ":", "5", "μm", "." ] } ]
PMC11674891	Band intensities were normalized to β-actin and quantified using ImageJ (version 1.54j).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Band", "intensities", "were", "normalized", "to", "β-actin", "and", ...
PMC11743316	ROS that derive from mitochondria (mROS) are becoming recognized as signaling molecules that influence the functioning of cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ROS", "that", "derive", ...
PMC6222726	Notably, cubebin (3) is usually the starting material for the semi-synthetic preparation of hinokinin (1) and other lignans .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notably...
PMC9784246	Additionally, topical treatment with epigallocatechin gallate significantly decreased the lesion size and parasite load of the intracellular amastigotes of L. amazonensis .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ...
PMC10507284	Meanwhile, the STS patient with a diminished TROAP expression exhibits an enhanced trend of several immune cells, such as recruiting CD4 T cells, dendritic cells, macrophages, and so on (Figure 4C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11519583	It has been shown that glycerol injection elicits anti-inflammatory macrophage activation and induces production of anti-inflammatory cytokines compared to Ctx injection .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "has", "been...
PMC11575040	Similar to the effects observed with LINC00094 knockdown, the overexpression of miR-1270 significantly impeded the ability of melanoma cells to proliferate and form colonies (Fig. 6A–H).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10926885	We used the corr.test function of the R package ‘psych’ (version 2.1.6) to compute the immune infiltration score.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "used",...
PMC11139449	This cloning process was carried out using the digestion/ligation method. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "cloning", "process", "was", "carried", "out", "using", "the", "digestion/ligation",...
PMC11543885	Rank Proteins: Rank the proteins that pass the FDR<0.05 threshold in descending order by log2 [fold change (stimulated/unstimulated)].b.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Rank", "Proteins", ":", ...
PMC11301242	This suggests that ecDNA enables the simultaneous rapid amplification of protein-coding genes and associated noncoding elements, potentially contributing together to tumor emergence and evolution.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	In both arms, the most common liver, effusion and renal TEAEs, respectively, were increased ALT and/or AST (34.0% vs 8.3% [G3/4: 22.0% vs 2.3%]), pleural effusion (5.2% vs 1.9% [G3/4: 0.7% vs 0.4%]) and increased blood creatinine (6.7% vs 8.3% [G3/4: 0.4% vs 0.4%]).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11607638	In D. melanogaster, SK not only inhibits food intake but also regulates mating, aggression, and stress. , ,	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "D.", "melan...
PMC11792740	Tumor-induced glucose restriction in ovarian cancer results in the downregulation of methyltransferase EZH2 expression in T cells, leading to T-cell dysfunction through the Notch signaling pathway.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Finally, we evaluated the association between TAC plasma levels and overall survival (OS) by means of multivariate analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Finally", ",", "w...
PMC11694346	After reacting with biothiols, the activated probe exhibits a maximum emission at 630 nm, resulting in a notably large Stokes shift of ≈200 nm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973	Statistical analysis was performed with SPSS 2017.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "analysis", "was", "performed", "with", "SPSS", "2017", "." ] } ]
PMC9429973	These cells were transfused 3 to 5 days after lymphocyte removal.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "cells", "were", "transfused", "3", "to", "5", "days", "after", "lymphocyte",...
PMC10605143	Cells were harvested by trypsinization and counted, and 5 × 10 cells were used for staining.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "harvested", "by", "trypsinizatio...
PMC10523483	Consistent with the in vitro results, KH mice with H1.2 deficiency presented significantly suppressed NSCLC progression (Fig. 2C), as reflected by reduced tumor size, tumor number, and tumor burden (Fig. 2D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11400680	Figure 4A shows the ground truth bounding boxes generated by human experts while Figure 4B shows the predictions of our prompt generator.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Figure", "4A...
PMC11413393	Parent ion mass tolerance was set at 15 ppm and an MS/MS fragment ion mass tolerance at 0.4 Da.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Parent", "ion", "mass", "toleranc...
PMC9596868	After centrifugation at 13,000 rpm for 10 min at 4°C, the supernatant was collected and the extract for 10,000 cells was used for PCR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11472639	However, plasma cells were largely unchanged, and NK-cells expressing CD38 – the daratumumab target antigen – increased in blood.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "p...
PMC9429973	DFP is a membrane-permeable iron chelator with a lower iron affinity (pFe=19.3) than DFO (pFe=26.6), DFX (pFe=23.5), or transferrin (pFe=22.3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6600253	In addition, Rentschlera et al. demonstrated that both IFN-γ and TNF can induce senescence in MCF-7 breast cancer cells and A204 rhabdomyosarcoma cells, resulting in reduced tumor cell proliferation .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", ...
PMC11066331	The calibration was performed externally using the Bacterial Test Standard 3.5–17 kDa.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "calibration", "was", "performed", "externally", "using", "the", "Bacterial", ...
PMC11736898	Vitamin D3 (D3) is synthesized in keratinocytes from the precursor 7-dehydrocholesterol in response to ultraviolet radiation in sunlight.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Vitamin", "D3", "(", "...
PMC10291556	SI—average selectivity index calculated as IC50 (MRC-5)/average IC50 (cancer cells).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SI", "—", "average", "selectivity", "index", "calculated", "as", ...
PMC11787381	p < 0.05 was considered significant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "p", "<", "0.05", "was", "considered", "significant", "." ] } ]
PMC10040136	Our findings showed that both contact-CM and recombinant TGF-β2 protein provoked the activation of the PI3K-AKT signaling pathway of GIST and phosphorylated its downstream proteins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC8010066	The primers used from different studies (Savli et al. 2003; Bustin et al. 2005; Steindler et al. 2009; Choudhury et al. 2016; Falahat et al. 2016; Dehbashi et al. 2020) and are listed in Table 1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Hence, research mainly relies on the use of transgenic and xenograft animal models.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hence", ",", "research", "mainly", "relies", "on", "the", "use",...
PMC10048572	Upon subsequent cloning of selected primary clones, it was found that out of 350 subclones of the STR-stable WIL2-S clone, only two (0.57%) have lost the Y-chromosome amelogenin marker.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3019555	Ago2 protein was detected by immunoblotting.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ago2", "protein", "was", "detected", "by", "immunoblotting", "." ] } ]
PMC11765988	Pathway analysis using Reactome and KEGG identified significant modifications, with the “proteasome” pathway and the “citrate cycle (TCA cycle)” among the most altered.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11539788	RNF19A mRNA expression was analysed in various cancers using the TIMER database. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RNF19A", "mRNA", "expression", "was", "analysed", "in", "various", "cancers...
PMC11496491	Through RT-PCR verification of some differentially expressed genes, it was found that the results of gene expression profile chip detection were consistent, which further proved the reliability of gene expression profile chip data.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11755519	HDLEC, human dermal lymphatic endothelial cells; HLEC, human lymphatic endothelial cells; HUVEC, human umbilical vein endothelial cells; TGF-β, transforming growth factor β.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC10743717	especially because the reported Km values of ABAD/ERAB for (−)-2-octanol, (+)-2-octanol and (±)-2-octanol were as high as 43, 86 and 87 mM, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11476264	Taken together, we confirm that EMT transcription factor ZEB1 plays a major role in the invasion and metastasis of lung cancer and that FBXO11 can ubiquitinate ZEB1 and be recognized by the proteasome for degradation, thereby inhibiting the invasion and metastasis of lung cancer cells (Figure 7).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10877303	Robustaflavone, a biflavonoid extracted from N. domestica fruits, Garcinia latissima Miq.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Robustaflavone", ",", "a", "biflavonoid", "extracted", "from", "N.", "domes...
PMC11754784	e Flow cytometry analysis-based fluorescence intensity statistics of four different cancer cells treated with cage-Nb and DNP1 in TAMRA channel and FAM channel.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "e", ...
PMC11075223	In addition, total glycosides of C. dahurica against hepatoma through inducing cycle arrest and apoptosis in HepG2 cells and inhibiting the implanted mouse H22 tumor growth dose-dependently .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "B-CellLine", "...
PMC11730000	Additionally, silymarin, a prominent flavonolignan found in Silybum marianum L., has been indicated to lessen DOX-induced cytotoxicity by shielding the cell membrane from damage caused by free radicals.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9000591	The highest TPC (1.77 mg GAE/g DW) was found in the SM extract.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "highest", "TPC", "(", "1.77", "mg", "GAE/g", "...
PMC10671321	In that study, we looked at the molecular phenotypes of mice-ColQ-deficient muscle cells focusing on the number and the shape of the clusters as well as on the levels of RNAs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6642070	Supplementation of DCA eliminated the increased lactate production by fluvastatin (25% and 45% decrease compared to control and fluvastatin single treatment respectively), consisting with the potent glycolysis inhibitory activity of DCA (Fig. 6a).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11643361	The cytotoxicity of nine Ru(II) tpm complexes (40–48, Figure 5) was evaluated against human cervical carcinoma (HeLa), colorectal carcinoma (HCT116), rhabdomyosarcoma (RD), breast cancer (MCF-7), and skin melanoma (518A2) cell lines, as well as against non-tumoral human fibroblasts (MRC5pd30), using cisplatin as a cont...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", ...
PMC6268318	Di Carlo et al. demonstrated immuno-stimulating activity with a suspension of powdered leaf.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Di", "Carlo", "et", "al.", "demonstrated", "immuno-stimulating", "activity", ...
PMC11737091	PPI network of DBF4. (	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "PPI", "network", "of", "DBF4", ".", "(" ] } ]
PMC11240571	All cell cultures were maintained in 5% CO2 at 37 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "cell", "cultures", "were", "maintained", "in", "5", "%", "CO2"...

PMC11591052

The reference gene selected was β-actin.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "reference", "gene", "selected", "was", "β-actin", "." ] } ]

PMC11792888

All signals from proteins of interest were normalized based on the (-tubulin or (-actin signals.

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PMC10976516

So it is tempting to use immune cells in such a way that their natural features can be combined with a role as OV carrier cells and stimulate an even more robust antitumor response.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Most adverse events (AEs) were of grade 1 to 2.

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PMC8623816

A sequence search with BLASTP suggested that this protein was most closely related to the RdRp of some viruses in the family Partitiviridae, such as the Penicillium aurantiogriseum partiti-like virus .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10772747

The results in Figure 5 (C and D) showed that the cell cycle distribution in the DOX and 1,4-naphthoquinone treatment groups did not significantly differ from the untreated control group (P>0.0001).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9684669

In contrast, CREB1 phosphorylation remained lower in the combined treatment, indicating that CAMK2 inhibitors repressed the CAMK2/CREB1 pathway ( Figures 6E.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...

PMC11349530

Cancer cells are capable of producing various growth factors such as VEGF, TGF-β, PDGF, etc.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cancer", "cells", "are", "capable", "o...

PMC6684588

In addition, activin A and activin B are implicated as endogenous inhibitors of muscle growth that act synergistically with myostatin.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ...

PMC9429973

Methods: Hem/oncs participated in a 22-minute segmented online multi-media activity consisting of videos portraying realistic physician–patient interactions followed by expert commentaries.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC9221284

This result validates the capability of the 9E10 antibody used against the C-terminal region to detect c-Myc protein isoforms with an unaltered C-terminal region, and to some extent the identity of the bands that were described in Figure 2A,B. Of note, c-Myc1 (67 kDa) was undetectable in both lymph nodes (this work) an...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS) were graded by ASBMT, AE according to CTCAE 5.0.

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PMC9621239

Sn at each amino acid site in genotype-C and genotype-D clones. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Sn", "at", "each", "amino", "acid", "site", "in", "genotype-C", "and", "ge...

PMC7294030

Fluorouracil (5-FU), the positive control, also significantly increased the proportion of cells in the G0/G1 phase from 74.7 ± 1.97 % to 81.07 ± 1.66 % as compared to negative controls (Figure 3).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10568263

Cancer is a leading global health issue with increasing incidence and mortality every year, impacting all communities worldwide regardless of religion, race, or age.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10938336

After 24 h, the cells were treated with the compounds at concentrations between 1.875 and 30.0 μM. MTT (3-(4,5-dimethylthiazol-2yl)-2,5-diphenyltetrazolium bromide) solution (201 of 0.5 mg/mL) was added to each well after 24 h of incubation, with the incubation continuing for additional 4 h at 37 °C.

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PMC9429973

Patients will be referred early to an allograft of bone marrow,thus avoiding the fatal consequences of sepsis due to neutropenia or hemorrhage on severe thrombocytopenia M. Bektaş, A. E. Eşkazan, T. O. Tiryaki, R. Mullai, T. Elverdi, A. Salihoğlu, M. Tiribelli, M. C. Ar, S. Öngören, Z. Başlar, M. Nalçaci, T. Soysal Dep...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11727907

This study aims to investigate the effect of IGF-1 on PKM2 modulation of RPE cells and whether co-treatment with klotho may preserve it.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", ...

PMC10698968

MF-R 3 and 143B cells were seeded at 2*10 cells/cm density in technical quintuplicate into 96-well plates and cultured for 7 days at standard conditions.

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PMC9429973

Reasons for FEDR discontinuation (D/C) in >1 pt were lack of efficacy (n=5), AEs (n=4), disease progression (n=2), pt decision (n=2), and to undergo transplant (n=2).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11755624

lncRNAs regulate pivotal signaling pathways linked to immune responses and inflammatory processes.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "lncRNAs", "regulate", "pivotal", "signaling", "pathways", "linked", "to", "immune", ...

PMC5173112

of three independent experiments, each performed in triplicate. (

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PMC11758416

Periodically stain the CD32-expressing L cells for CD32 to ensure expression is not lost.

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PMC9429973

The majority of cases (90.9%) showed expression of MYC.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "majority", "of", "cases", "(", "90.9", "%", ")", "showed", "express...

PMC9429973

Functional experiments were performed to depict the role of a BMP2-induced subset of γδ T cells in the anti-AML activity of effector γδ T cells.

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PMC11489351

An FDR < 0.05 cut-off was applied to our RNA-Seq analysis for pathway analysis and determination of targets for biochemical validation.

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PMC9429973

In DLBCL, the most frequent mutation was a novel C>T mutation at position 4 (g.4C>T) found in 8.4% of cases.

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PMC9429973

We hypothesized that adding parsaclisib may improve clinical benefit with a manageable safety profile in this pt population.

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PMC9878562

Conversely, ACKR3 was expressed only on a fraction of VAL-wt (10-18%), despite their clonal nature and continuous mRNA levels of the receptor (32).

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PMC11587606

Statistical analysis was performed by GraphPad Prism 5.0 (GraphPad Software, CA, USA).

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PMC11248911

When compared to sorafenib (pIC50 = 7.4) as the reference drug, derivative 8 inhibited VEGFR2 at pIC50 value of 6.7.

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PMC8389560

In this work, it was shown for the first time that the generation of Ca signals in A-172 cells occurs in response to the application of various concentrations of selenium nanoparticles.

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PMC11770199

Human colon cancer cells of HCT8 were transfected with PCDH-GFP or PCDH-GFP-p14.

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PMC11566417

Neutrophils collected from 3 cows were tested against each treatment and the plates were incubated for 1 h at 37°C before inserts were removed.

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PMC11621493

Ct values for Pla2g4d are shown above each bar.

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PMC5311252

Total LC-MS run time was 74 min.

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PMC11267830

Furthermore, splicing events for EZH2 and THOC1 in primary cells posttreatment were confirmed, consistent with the cell line outcomes (Fig. 9c).

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PMC11095939

B, F, J, N) Statistical analysis of the cell cycle distribution. (

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PMC11361748

Collectively, these results indicate a role for CXCR2 and CXCR3 ligands and their receptors in mediating the keratinocyte- and K17-dependent recruitment of neutrophils, in both mouse skin in vivo and human keratinocyte cultures ex vivo.

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PMC10748106

The plot of Figure 11 shows that the mathematical model has an acceptable descriptive ability, considering the limited number of compounds employed for the model.

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PMC9479186

Inoculation was performed aseptically.

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PMC9046263

A single DNA band was localized around 170–190 bp, excised and DNA was extracted using the QIAquick gel extraction kit (Qiagen, 28,704) according to manufacturer’s protocol.

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PMC11481779

We have calculated pearson correlation of the insulation scores for all heatmaps (we have filtered out the ones that in real Hi-C data are starting/ending with zeros, as well as the ones that contain more than 5% of zero values).

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PMC10698968

Before treatment, spheroids’ formation was allowed for 5 days.

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PMC9429973

During the entire period of the study 5 deaths were registered: 3 were related to progression, 2 – because of COVID-19.

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PMC11683240

Blue line: chromatogram from the chromatographic fractionation process, gray bars = screening result, green bars: screening results that were considered as hits and or subjected to further chromatographic fractionation).

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PMC9429973

Image: Summary/Conclusion: Our results show that Hybridization capture NGS is a good technique to detect KMT2A-PTDs, with a better sensibility than PCR.

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PMC11297139

Scale bar: 5 μm.

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PMC11674891

Band intensities were normalized to β-actin and quantified using ImageJ (version 1.54j).

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PMC11743316

ROS that derive from mitochondria (mROS) are becoming recognized as signaling molecules that influence the functioning of cells.

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PMC6222726

Notably, cubebin (3) is usually the starting material for the semi-synthetic preparation of hinokinin (1) and other lignans .

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PMC9784246

Additionally, topical treatment with epigallocatechin gallate significantly decreased the lesion size and parasite load of the intracellular amastigotes of L. amazonensis .

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PMC10507284

Meanwhile, the STS patient with a diminished TROAP expression exhibits an enhanced trend of several immune cells, such as recruiting CD4 T cells, dendritic cells, macrophages, and so on (Figure 4C).

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PMC11519583

It has been shown that glycerol injection elicits anti-inflammatory macrophage activation and induces production of anti-inflammatory cytokines compared to Ctx injection .

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PMC11575040

Similar to the effects observed with LINC00094 knockdown, the overexpression of miR-1270 significantly impeded the ability of melanoma cells to proliferate and form colonies (Fig. 6A–H).

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PMC10926885

We used the corr.test function of the R package ‘psych’ (version 2.1.6) to compute the immune infiltration score.

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PMC11139449

This cloning process was carried out using the digestion/ligation method. (

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PMC11543885

Rank Proteins: Rank the proteins that pass the FDR<0.05 threshold in descending order by log2 [fold change (stimulated/unstimulated)].b.

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PMC11301242

This suggests that ecDNA enables the simultaneous rapid amplification of protein-coding genes and associated noncoding elements, potentially contributing together to tumor emergence and evolution.

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PMC9429973

In both arms, the most common liver, effusion and renal TEAEs, respectively, were increased ALT and/or AST (34.0% vs 8.3% [G3/4: 22.0% vs 2.3%]), pleural effusion (5.2% vs 1.9% [G3/4: 0.7% vs 0.4%]) and increased blood creatinine (6.7% vs 8.3% [G3/4: 0.4% vs 0.4%]).

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PMC11607638

In D. melanogaster, SK not only inhibits food intake but also regulates mating, aggression, and stress. , ,

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PMC11792740

Tumor-induced glucose restriction in ovarian cancer results in the downregulation of methyltransferase EZH2 expression in T cells, leading to T-cell dysfunction through the Notch signaling pathway.

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PMC9429973

Finally, we evaluated the association between TAC plasma levels and overall survival (OS) by means of multivariate analysis.

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PMC11694346

After reacting with biothiols, the activated probe exhibits a maximum emission at 630 nm, resulting in a notably large Stokes shift of ≈200 nm.

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PMC9429973

Statistical analysis was performed with SPSS 2017.

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PMC9429973

These cells were transfused 3 to 5 days after lymphocyte removal.

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PMC10605143

Cells were harvested by trypsinization and counted, and 5 × 10 cells were used for staining.

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PMC10523483

Consistent with the in vitro results, KH mice with H1.2 deficiency presented significantly suppressed NSCLC progression (Fig. 2C), as reflected by reduced tumor size, tumor number, and tumor burden (Fig. 2D).

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PMC11400680

Figure 4A shows the ground truth bounding boxes generated by human experts while Figure 4B shows the predictions of our prompt generator.

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PMC11413393

Parent ion mass tolerance was set at 15 ppm and an MS/MS fragment ion mass tolerance at 0.4 Da.

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PMC9596868

After centrifugation at 13,000 rpm for 10 min at 4°C, the supernatant was collected and the extract for 10,000 cells was used for PCR.

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PMC11472639

However, plasma cells were largely unchanged, and NK-cells expressing CD38 – the daratumumab target antigen – increased in blood.

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PMC9429973

DFP is a membrane-permeable iron chelator with a lower iron affinity (pFe=19.3) than DFO (pFe=26.6), DFX (pFe=23.5), or transferrin (pFe=22.3).

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PMC6600253

In addition, Rentschlera et al. demonstrated that both IFN-γ and TNF can induce senescence in MCF-7 breast cancer cells and A204 rhabdomyosarcoma cells, resulting in reduced tumor cell proliferation .

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PMC11066331

The calibration was performed externally using the Bacterial Test Standard 3.5–17 kDa.

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PMC11736898

Vitamin D3 (D3) is synthesized in keratinocytes from the precursor 7-dehydrocholesterol in response to ultraviolet radiation in sunlight.

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PMC10291556

SI—average selectivity index calculated as IC50 (MRC-5)/average IC50 (cancer cells).

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PMC11787381

p < 0.05 was considered significant.

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PMC10040136

Our findings showed that both contact-CM and recombinant TGF-β2 protein provoked the activation of the PI3K-AKT signaling pathway of GIST and phosphorylated its downstream proteins.

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PMC8010066

The primers used from different studies (Savli et al. 2003; Bustin et al. 2005; Steindler et al. 2009; Choudhury et al. 2016; Falahat et al. 2016; Dehbashi et al. 2020) and are listed in Table 1.

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PMC9429973

Hence, research mainly relies on the use of transgenic and xenograft animal models.

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PMC10048572

Upon subsequent cloning of selected primary clones, it was found that out of 350 subclones of the STR-stable WIL2-S clone, only two (0.57%) have lost the Y-chromosome amelogenin marker.

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PMC3019555

Ago2 protein was detected by immunoblotting.

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PMC11765988

Pathway analysis using Reactome and KEGG identified significant modifications, with the “proteasome” pathway and the “citrate cycle (TCA cycle)” among the most altered.

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PMC11539788

RNF19A mRNA expression was analysed in various cancers using the TIMER database. (

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PMC11496491

Through RT-PCR verification of some differentially expressed genes, it was found that the results of gene expression profile chip detection were consistent, which further proved the reliability of gene expression profile chip data.

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PMC11755519

HDLEC, human dermal lymphatic endothelial cells; HLEC, human lymphatic endothelial cells; HUVEC, human umbilical vein endothelial cells; TGF-β, transforming growth factor β.

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PMC10743717

especially because the reported Km values of ABAD/ERAB for (−)-2-octanol, (+)-2-octanol and (±)-2-octanol were as high as 43, 86 and 87 mM, respectively.

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PMC11476264

Taken together, we confirm that EMT transcription factor ZEB1 plays a major role in the invasion and metastasis of lung cancer and that FBXO11 can ubiquitinate ZEB1 and be recognized by the proteasome for degradation, thereby inhibiting the invasion and metastasis of lung cancer cells (Figure 7).

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PMC10877303

Robustaflavone, a biflavonoid extracted from N. domestica fruits, Garcinia latissima Miq.

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PMC11754784

e Flow cytometry analysis-based fluorescence intensity statistics of four different cancer cells treated with cage-Nb and DNP1 in TAMRA channel and FAM channel.

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PMC11075223

In addition, total glycosides of C. dahurica against hepatoma through inducing cycle arrest and apoptosis in HepG2 cells and inhibiting the implanted mouse H22 tumor growth dose-dependently .

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PMC11730000

Additionally, silymarin, a prominent flavonolignan found in Silybum marianum L., has been indicated to lessen DOX-induced cytotoxicity by shielding the cell membrane from damage caused by free radicals.

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PMC9000591

The highest TPC (1.77 mg GAE/g DW) was found in the SM extract.

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PMC10671321

In that study, we looked at the molecular phenotypes of mice-ColQ-deficient muscle cells focusing on the number and the shape of the clusters as well as on the levels of RNAs.

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PMC6642070

Supplementation of DCA eliminated the increased lactate production by fluvastatin (25% and 45% decrease compared to control and fluvastatin single treatment respectively), consisting with the potent glycolysis inhibitory activity of DCA (Fig. 6a).

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PMC11643361

The cytotoxicity of nine Ru(II) tpm complexes (40–48, Figure 5) was evaluated against human cervical carcinoma (HeLa), colorectal carcinoma (HCT116), rhabdomyosarcoma (RD), breast cancer (MCF-7), and skin melanoma (518A2) cell lines, as well as against non-tumoral human fibroblasts (MRC5pd30), using cisplatin as a cont...

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PMC6268318

Di Carlo et al. demonstrated immuno-stimulating activity with a suspension of powdered leaf.

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PMC11737091

PPI network of DBF4. (

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PMC11240571

All cell cultures were maintained in 5% CO2 at 37 °C.

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