OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11806106	They were also able to create a MOR sensor, called µMASS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "They", "were", "also", "able", "to", "create", "a", "MOR", "sensor", ",", ...
PMC9370419	The cccDNA transcription activity is regulated by the epigenetic modifications of DNA and histones that bind to cccDNA .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cccDNA", "transcription", "activity",...
PMC10831439	An empty vector was used as negative control (Raji-ctrl) (online supplemental data 2B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "An", "empty", "vector", "was", "used", ...
PMC11248911	g_mmpbsa can also be used to estimate the energy contribution per residue to the binding energy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "g_mmpbsa", "can", "also", "be", "used", "to", "e...
PMC9430060	Summary/Conclusion: Taken together, our analysis suggests that H3K4me3-BDs are created by super-enhancers and supports the new concept of epigenomic translocation, where the relocation of H3K4me3-BDs accompanies the translocation of super-enhancers, altering the local 3D genome.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3681794	In 791T cells there was no significant difference in etoposide-induced apoptosis between normoxia and hypoxia.	[ { "tags": [ "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "791", "T", "cells", "there", "...
PMC9429973	Hepatic involvement did not impact response to treatment and disease outcome.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hepatic", "involvement", "did", "not", "impact", "response", "to", "treatment", "and", ...
PMC7090062	All data are representative of three independent experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "data", "are", "representative", "of", "three", "independent", "experiments", "." ] } ]
PMC7685376	Pathway enrichment analysis used the KEGG pathway as a unit and applied a hypergeometric test to find pathways that compared to the entire proteomic background, were significantly enriched in candidate target proteins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	V114 recipients reported a higher proportion of injection-site AEs and vaccine-related systemic AEs compared to PCV13 in the adult cohort.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "V114", "recipients", "report...
PMC11680982	Effects of CDK4/6 inhibitor + endocrine therapy and triple combination treatment (neratinib, CDK4/6 inhibitor and endocrine therapy) on HER2 mRNA stability.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC8633974	Using a single broad-spectrum gRNA targeting LTR transduced at this same level but allowed viral rebound in ∼20% latently infected JLat cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Using",...
PMC9436459	In 2004, Lee et al. first discovered that the natural MDAA sanggenon D (128, IC50 = 7.3 μM) was a potent tyrosinase inhibitor (the positive control kojic acid, IC50 = 24.8 μM) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11648299	The NPR, hosted by the Swedish National Board of Health and Welfare, collects information on all inpatient and outpatient visits and uses the ICD-10-SE to register diagnoses.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10669966	We sought to discover novel LPS-subtype-specific oncogenes that could serve as precision medicine targets.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "sought", "to", "discover", "novel", "LPS-subtype-specific", "onc...
PMC11138140	Our results show that norepinephrine has a strong cardiomyocyte cell spreading effect by 24 h (Figure 1C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Our", "results", "show", "that", ...
PMC11741906	However, without functional validation and mechanistic studies such as gene knockdown, overexpression studies, and in vivo models, it is challenging to definitively determine whether these miRNAs function as oncogenes or tumor suppressors in ovarian cancer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11144200	A The secretion of IFN-γ in the activated CD8 T cells of different groups against the stimulations of corresponding tumor cells was detected by ELISPOT assay to indicate the significant involvement of LPS-RGD-Nb36-DOX and LPS-RGD-Nb36 with the increased amount of IFN-γ-producing CD8 T cells inducing by DC/tumor-FC vacc...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11240448	In summary, the cSTAR analysis demonstrated high robustness in analyzing oncogenic transformation, specifically the transition from non-malignant to malignant cell states.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC7823217	For advance management and estimating the prognosis, these classifications are very important.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "advance", "management", "and", "estimating", "the", "prognosis", ","...
PMC11593713	This understanding is essential for elucidating the pathological mechanisms involved in these infections and for developing more effective therapeutic approaches.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "understanding", "is"...
PMC11718274	Fig. aa a Fig. 1 X-ray diffraction (XRD) pattern detected using X-Ray Diffractometers confirmed the purity and crystalline structure of purchased Y 2 O 3 NPs X-ray diffraction (XRD) pattern detected using X-Ray Diffractometers confirmed the purity and crystalline structure of purchased Y 2 O 3 NPs Fig. 2 Particles’ Siz...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11795610	Keratinocytes, which are the predominant cell type in the human epidermis, undergo a differentiation process that is crucial for the formation of the skin barrier.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Secondary endpoints included objective response rate (ORR), duration of response (DOR), progression-free survival (PFS), overall survival (OS), safety, and biomarker assessments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11538390	Three independent measurements were performed for each transfection group, and three biological replicates were performed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Three", "independent", "measurements", "were", "performed", ...
PMC9429973	C. López, A. Rivas-Delgado, F. Nadeu, M. Grau, A. Rivero, J. Boschs-Schips, M. Alcoceba, G. Tapia, L. Luizaga, C. Bárcena, N. Kelleher, M. Pablo, O. Balague, G. Frigola, N. Villamor, L. Magnano, T. Baumann, A. Muntañola, J. M. Sancho-Cia, A. M. García-Sancho, E. Gonzalez Barca, F. Climent, E. Campo, E. Giné, A. López-G...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11701801	Data are presented as the mean ± SD; n = 3 independent experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "presented", "as", "the", "mean", "±", "SD", ...
PMC7351993	The fluids recovered from the collection and waste tubes were dispensed into commercially available glass base dishes (Triple-well glass base dish, 3970-103, IWAKI) for successive centrifugal concentration (at 200 × g for 3 min) since PDMS affects BODIPY staining.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8662250	MTT‐formazan assay determining the quantification of cell viability in treated Caco‐2 cells exposed to spike protein (SP) (0.1–10 ng/ml) in the presence of CBD (10–10 M) in the presence/absence of PPAR‐γ antagonist GW9662 (9 nM) at 24 h; (b) immunofluorescence microphotographs showing 4′,6‐diamidino‐2‐phenylindole (DAP...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11633763	To assess apoptosis, cells (1 × 10) were stained with Annexin V fluorescein isothiocyanate and propidium iodide apoptosis detection kit (BD Biosciences) according to the manufacturer's instructions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10547921	At the same time, it is a substrate of multidrug-resistant protein 1 (MDR1), a transporter that reduces the potency of some antibody-maytansine-like conjugates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6803987	Animal vital signs including body weight, gait, food intake, feather color, health status and response to stimuli were supervised in the course of the tests.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11615828	To perturb synaptic vesicle motility with better spatiotemporal resolution, we optogenetically trapped Cry2‐VAMP2‐labeled vesicles on EMTB‐CIBN‐bound MTs in a reversible manner (t 1/2 on: 7.0 ± 1.9 s; t 1/2 off: 68.1 ± 15.2 s; Figure 5e,f; Video S26, Supporting Information).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7229095	The cell culture media are necessary to supply sufficient nutrients for the cell growth for mammalian cells such as Chinese hamster ovary (CHO) cells, and applying appropriate media is important in developing cell line and cell culture process with high productivity and quality.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "B-CellLine", "O", "...
PMC4685411	The optimization of complex biotechnological production processes with approved Design of Experiment (DoE) methods is therefore time-consuming and cost-intensive.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "optimization", ...
PMC11489351	Assays were run in technical duplicates and averaged for each data point.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Assays", "were", "run", "in", "technical", "duplicates", "and", "averaged", "for...
PMC9581083	Patients with symptoms such as fever due to warm-damp epidemic poisoning should be treated with substances that clear heat, detoxify and dredge the collaterals, dispel cold and dehumidify, so the appropriate TCM formulas are those that clear heat, detoxify dampness and relieve asthma as the core treatment method.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3164356	The CHO-K1 genome has homologs to all six human ST3Gal enzymes, which form α(2,3) linkages of sialic acid to galactose.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "CHO-K...
PMC2944824	Briefly, following treatment cells were harvested and lysed using the Cytosol Extraction Buffer Mix with DTT and Protease Inhibitors, cells were incubated on ice for 10 min prior to being homogenized in a dounce homogenizer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The most common sites of relapse were lymph nodes (3), soft tissue (3) and CNS (2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC9429973	Each journal´s website was screened, and we extracted data on the composition of the editorial board, including editors-in-chief and associate editors and excluded editorial board members with other roles which are not of editorial capacity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10419319	Concerning cisplatin resistance, the dysregulated glycolytic pathway provides a survival advantage to resistant cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Concerning", "cisplatin", "resistance", ",", "the", "d...
PMC11795610	HC: HC-067047, TRPV4 inhibitor.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HC", ":", "HC-067047", ",", "TRPV4", "inhibitor", "." ] } ]
PMC10329074	There has been significant progress in the treatment of patients with ccRCC, with improved knowledge of disease biology and the introduction of targeted agents and immunotherapies (Atkins and Tannir 2018).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	of Hematology, First Faculty of Medicine, Charles University, and General University Hospital, Prague, Czechia Background: The treatment of blast crisis of chronic myeloid leukaemia (BC-CML) remains difficult and the outcome of patients is poor.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7334607	We hypothesize that Ewing's sarcoma cell lines repeatedly exposed to standard chemotherapy will demonstrate divergent evolutionary paths between evolutionary replicates despite nearly identical experimental conditions and initial genotype.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8711270	Comparison of various γRV production methods.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Comparison", "of", "various", "γRV", "production", "methods", "." ] } ]
PMC11697065	E: Correlation of mRNA abundance with protein abundance for HC from clones expressing MonoAb2 and BisAb2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "E", ":", "Correlation", "of", "mRNA", "abun...
PMC11477621	The crude product was purified by silica gel chromatography to give the brown solid (77 mg, 20%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "crude", "p...
PMC11380329	= effect for drug a in combination E (cb) = effect for drug b in combination E (da) = effect of drug a alone E (db) = effect of drug b alone In an attempt to further clarify whether P treatment co-supplemented or not with Vit D affects the tumorigenicity of OVCAR4 cells, we investigated the expression of Ki67 which is ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9275501	PMX/DCK-QCN-NE had good intestinal permeability and increased cell absorption of PMX/DCK and Que.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PMX/DCK-QCN-NE", "had", "good", "intestinal", "permeability", "and", "increased",...
PMC11661040	Western blot and immunohistochemistry (IHC) techniques were employed to detect the expression of relevant proteins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Western", "blot", "and", "immunohistochemistry", ...
PMC11228511	NM ruptures and nuclear blebs are associated with an abnormal nuclear lamin meshwork in Lmnb1 and Zmpste24 SMCs. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "NM", "ruptures", "and", "nuclear"...
PMC9577200	However, the results of this study support the view that graphene does not act as an antibacterial agent, so it may be used in biomedical nanotechnologies, such as facilitating surface-attached stem cells for orthopedics.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11531735	Comparison of tumor-free survival of ER121 treated groups ER121 high, ER121 low, Herceptin and PBS treated groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Comparison", "of", "tumor-free", ...
PMC11361748	Of the 253 human genes homologs, 209 genes showed expression in the PSOR data set.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Of", "the", "253", "human", "genes", "homologs", ...
PMC11506670	HCT116 provides the colorectal and epithelial background, but, similar to other commonly used colorectal cancer cell lines with mutations in either KRAS or PIK3CA, or both, it may mask the phenotypic effects of introduced mutations .	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10033453	We found that the one mouse found moribund on day 6 had the highest level of ALT, and serum levels of ALB and ALP were elevated in a dose-dependent manner 15 days after treatment with VMG.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10854447	Molecular operating environment (MOE) software was used, as well as the crystal structure of the EGFR in complex with Erlotinib (PDB: 1M17).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8382973	PBS male rectum 1, 2; PBS female vagina 25, 26; gel male rectum 3, 4; gel female vagina 27, 28; 2% SFT gel male rectum 5, 6; 2% SFT gel female vagina 29, 30. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Systemic mastocytosis with an associated hematologic neoplasm (SM-AHN) is both the most common and most heterogenous subtype of AdvSM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Systemic", "mastocytosi...
PMC11767725	These insights provide a promising framework for developing microbiome-based therapies to address a range of dermatological and systemic diseases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "insights", "provide", "a...
PMC11472639	Lymphocytes were identified in a SSC-A × FSC-A plot prior to the removal of doublets in a FSC-H × FSC-A plot.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lymphocytes", "were", ...
PMC11401358	Those without injured caudal fins were regarded as the control group, and those with injured caudal fins were regarded as the positive group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC6461034	To assess the global correlation of INKA with cell line drug efficacy data, we analyzed our cell line use cases (Fig 2) along with two cancer cell panels, with publicly available label‐free phosphoproteomics data (Piersma et al, 2015; van der Mijn et al, 2015; Humphrey et al, 2016) and associated drug IC50 data with dr...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11650848	Withdrawal after randomisation (n = 25) or reasons for exclusion from the intervention are indicated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Withdrawal", "after", "randomisation", "(", "n", ...
PMC10547921	The payload in NIR-PIT drugs is not a cytotoxic substance, but a water-soluble phthalocyanine derivative (e.g., the silicon phthalocyanine derivative IR700 (IRDye700DX) (128)) (Fig. 22A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11055510	B, C) RT-qPCR verified the effect of transfection of ov-circMAN1A2 in SKOV3 cells (B) or si-circMAN1A2 in A2780 cells on circMAN1A2 expression (C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "...
PMC10452486	Spontaneous arthritis was also observed in HLA-B27 transgenic mice lacking B2m (HLA-B27+ B2m−/−) but not in HLA-B27+ B2m+/− mice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11783017	However, the effect of ROS-responsive nanomedicines in promoting tumor regression is not ideal due to insufficient local ROS supply in tumors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",...
PMC11731614	In this study, we provide the first comprehensive isolation and molecular characterization of KDEV protein and microRNA cargo in both RD and HFD mice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11013014	All the synthesised compounds were evaluated and screened for their in vitro anti-proliferative activities against two cancer cell lines (HL60 and HCT116).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10988555	The pellet was resuspended in PBS 1× and centrifuged at 3000 × g for 5 min at 4 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "pellet", "...
PMC11527437	The most promising TCRs warrant testing in patients with KRAS G12V–positive cancers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "most", "promising", "TCRs", "warrant", "testing", "in", "...
PMC11739504	Nuclei were stained with DAPI (blue).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Nuclei", "were", "stained", "with", "DAPI", "(", "blue", ")", "." ] } ]
PMC11488203	In more detail, the amount of viable GFP-positive cells was significantly reduced by about 50% after treatment of the MDA-MB-231 cancer cells with the different taxol-loaded exosomes or with 1 nM taxol.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", ...
PMC11739484	Panel (B) displays box plots illustrating the promoter methylation levels of the MMPs in SKCM and control cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Panel", "(", "B",...
PMC11679326	Previously, researchers linked the presence of β1,6-GlcNAc branches on N-glycans to tumor metastasis .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Previously", ",", "researchers", "linked", "the", "presence", "of", ...
PMC6461034	We explored implementation of an iBAQ procedure (Schwanhäusser et al, 2011) to correct for the number of phosphopeptides per kinase and the number of substrates per kinase.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11634027	To make Flp-out Dachs:GFP clones, animals were cultured at 18°C for 7 days, heat-shocked for 5 min at 35°C, and then wing discs were dissected out 18-24 h later.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10507284	At present, several studies have proven that the TROAP is elevated in glioma, liver cancer, prostate cancer, colon cancer, and other tumor tissues, and its expression level is negatively correlated with the survival prognosis of tumor patients. , , ,	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Decreased level of IL8 and SOX9 normalized in remission.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Decreased", "level", "of", "IL8", "and", "SOX9", "normalized", "in", "remission", "." ] } ]
PMC11759751	The experimental procedure of chidamide on CD19 CAR T cells in preparation (A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "experimental", "procedure", "of", "chidamide", "on", ...
PMC11697703	For miR-365 and miR-193b gain-of-function experiments, a CAG/H1 promoter plasmid was used to drive expression of GFP and mature miRs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "miR-365", ...
PMC10154881	To demonstrate the antitumor effects of rMV‐SLAMblind in vitro, the cell viability of E.G‐7/N4 or B16/N4 and their parental cells was determined by WST‐1 assay after infection with rMV‐SLAMblind at an MOI of 2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6742971	There is increasing evidence that low avidity T cells do not hinder their high avidity counterparts.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "is", "increasing", "evidence", "that", "low",...
PMC9429973	The median duration of exposure was 2.08 (range, 0.04-4.13) yrs with more than half (27 [56.3%]) of pts receiving treatment for ≥96 wks; the median daily dose intensity was 398.3 (range, 179-400) mg/day.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11703992	Given that pleiotropy between exposures and outcomes may introduce bias, a horizontal pleiotropy test was conducted on the eQTL and GWAS data.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Given",...
PMC9429973	No difference in the sensitivity to treatment with Bz was observed between mutated and wild-type patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "difference", "in", "the", "sensitivity", "to", ...
PMC11786767	D: Loss of Ki-67 reduces chromosome area.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "D", ":", "Loss", "of", "Ki-67", "reduces", "chromosome", "area", "." ] } ]
PMC11721587	Hh induces condensation of Fu and Ulk3 in the cytoplasm and primary cilium, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hh", "induces", "condensation", "of", "Fu", "and", "Ulk3", ...
PMC11258145	The lipid:curcumin ratios causing changes in the isotherms were significantly different for studied model mixtures being 8:1 for HL-60 cells and 64:1 for neuroblastoma cells (Fig. 1d,e).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "B-CellLin...
PMC11529598	J&K. The indicated cells (1 × 10) were subcutaneously injected into nude mice (n = 6) for xenograft assay.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "J&K.", ...
PMC11742231	Existing graph neural network (GNN) models for DRP encounter several limitations that hinder their performance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Existing", "graph", "neural", "network", "(", ...
PMC10589262	One-way ANOVA with a post-hoc test was performed to compare multiple means (p < 0.05, p < 0.01, **p < 0.001).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11742290	LGR5 silencing also reduced tumorigenesis in vivo using CRC and ovarian cancer models .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "LGR5", "silencing", "also", "reduced", "tumorigenesis", "in", "vivo", "usin...
PMC11679033	Obviously, to elucidate the apoptotic potentials of CIT and CBD, different methods and approaches have been used so far, which differ from each other in terms of sensitivity and the possibilities of elucidating the mechanisms underlying cell death.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11656380	Previous studies have shown that inhibition of NOTCH signaling induces cell-cycle arrest, apoptosis, and decreased proliferative capacity in a subset of T-ALL cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11040965	During the MGUS to MM transition, bone marrow becomes enriched in tumor plasma cells, as it is the primary site of their proliferation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11661040	D-E) The CCK-8 assay was employed to assess the impact of CGREF1 knockdown on cell proliferation stability. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "D-E", ")", "The", "CCK-8", ...

PMC11806106

They were also able to create a MOR sensor, called µMASS.

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PMC9370419

The cccDNA transcription activity is regulated by the epigenetic modifications of DNA and histones that bind to cccDNA .

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PMC10831439

An empty vector was used as negative control (Raji-ctrl) (online supplemental data 2B).

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PMC11248911

g_mmpbsa can also be used to estimate the energy contribution per residue to the binding energy.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "g_mmpbsa", "can", "also", "be", "used", "to", "e...

PMC9430060

Summary/Conclusion: Taken together, our analysis suggests that H3K4me3-BDs are created by super-enhancers and supports the new concept of epigenomic translocation, where the relocation of H3K4me3-BDs accompanies the translocation of super-enhancers, altering the local 3D genome.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC3681794

In 791T cells there was no significant difference in etoposide-induced apoptosis between normoxia and hypoxia.

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PMC9429973

Hepatic involvement did not impact response to treatment and disease outcome.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hepatic", "involvement", "did", "not", "impact", "response", "to", "treatment", "and", ...

PMC7090062

All data are representative of three independent experiments.

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PMC7685376

Pathway enrichment analysis used the KEGG pathway as a unit and applied a hypergeometric test to find pathways that compared to the entire proteomic background, were significantly enriched in candidate target proteins.

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PMC9429973

V114 recipients reported a higher proportion of injection-site AEs and vaccine-related systemic AEs compared to PCV13 in the adult cohort.

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PMC11680982

Effects of CDK4/6 inhibitor + endocrine therapy and triple combination treatment (neratinib, CDK4/6 inhibitor and endocrine therapy) on HER2 mRNA stability.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC8633974

Using a single broad-spectrum gRNA targeting LTR transduced at this same level but allowed viral rebound in ∼20% latently infected JLat cells .

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PMC9436459

In 2004, Lee et al. first discovered that the natural MDAA sanggenon D (128, IC50 = 7.3 μM) was a potent tyrosinase inhibitor (the positive control kojic acid, IC50 = 24.8 μM) .

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PMC11648299

The NPR, hosted by the Swedish National Board of Health and Welfare, collects information on all inpatient and outpatient visits and uses the ICD-10-SE to register diagnoses.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10669966

We sought to discover novel LPS-subtype-specific oncogenes that could serve as precision medicine targets.

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PMC11138140

Our results show that norepinephrine has a strong cardiomyocyte cell spreading effect by 24 h (Figure 1C).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Our", "results", "show", "that", ...

PMC11741906

However, without functional validation and mechanistic studies such as gene knockdown, overexpression studies, and in vivo models, it is challenging to definitively determine whether these miRNAs function as oncogenes or tumor suppressors in ovarian cancer.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11144200

A The secretion of IFN-γ in the activated CD8 T cells of different groups against the stimulations of corresponding tumor cells was detected by ELISPOT assay to indicate the significant involvement of LPS-RGD-Nb36-DOX and LPS-RGD-Nb36 with the increased amount of IFN-γ-producing CD8 T cells inducing by DC/tumor-FC vacc...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11240448

In summary, the cSTAR analysis demonstrated high robustness in analyzing oncogenic transformation, specifically the transition from non-malignant to malignant cell states.

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PMC7823217

For advance management and estimating the prognosis, these classifications are very important.

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PMC11593713

This understanding is essential for elucidating the pathological mechanisms involved in these infections and for developing more effective therapeutic approaches.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "understanding", "is"...

PMC11718274

Fig. aa a Fig. 1 X-ray diffraction (XRD) pattern detected using X-Ray Diffractometers confirmed the purity and crystalline structure of purchased Y 2 O 3 NPs X-ray diffraction (XRD) pattern detected using X-Ray Diffractometers confirmed the purity and crystalline structure of purchased Y 2 O 3 NPs Fig. 2 Particles’ Siz...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11795610

Keratinocytes, which are the predominant cell type in the human epidermis, undergo a differentiation process that is crucial for the formation of the skin barrier.

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PMC9429973

Secondary endpoints included objective response rate (ORR), duration of response (DOR), progression-free survival (PFS), overall survival (OS), safety, and biomarker assessments.

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PMC11538390

Three independent measurements were performed for each transfection group, and three biological replicates were performed.

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PMC9429973

C. López, A. Rivas-Delgado, F. Nadeu, M. Grau, A. Rivero, J. Boschs-Schips, M. Alcoceba, G. Tapia, L. Luizaga, C. Bárcena, N. Kelleher, M. Pablo, O. Balague, G. Frigola, N. Villamor, L. Magnano, T. Baumann, A. Muntañola, J. M. Sancho-Cia, A. M. García-Sancho, E. Gonzalez Barca, F. Climent, E. Campo, E. Giné, A. López-G...

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PMC11701801

Data are presented as the mean ± SD; n = 3 independent experiments.

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PMC7351993

The fluids recovered from the collection and waste tubes were dispensed into commercially available glass base dishes (Triple-well glass base dish, 3970-103, IWAKI) for successive centrifugal concentration (at 200 × g for 3 min) since PDMS affects BODIPY staining.

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PMC8662250

MTT‐formazan assay determining the quantification of cell viability in treated Caco‐2 cells exposed to spike protein (SP) (0.1–10 ng/ml) in the presence of CBD (10–10 M) in the presence/absence of PPAR‐γ antagonist GW9662 (9 nM) at 24 h; (b) immunofluorescence microphotographs showing 4′,6‐diamidino‐2‐phenylindole (DAP...

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PMC11633763

To assess apoptosis, cells (1 × 10) were stained with Annexin V fluorescein isothiocyanate and propidium iodide apoptosis detection kit (BD Biosciences) according to the manufacturer's instructions.

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PMC10547921

At the same time, it is a substrate of multidrug-resistant protein 1 (MDR1), a transporter that reduces the potency of some antibody-maytansine-like conjugates.

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PMC6803987

Animal vital signs including body weight, gait, food intake, feather color, health status and response to stimuli were supervised in the course of the tests.

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PMC11615828

To perturb synaptic vesicle motility with better spatiotemporal resolution, we optogenetically trapped Cry2‐VAMP2‐labeled vesicles on EMTB‐CIBN‐bound MTs in a reversible manner (t 1/2 on: 7.0 ± 1.9 s; t 1/2 off: 68.1 ± 15.2 s; Figure 5e,f; Video S26, Supporting Information).

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PMC7229095

The cell culture media are necessary to supply sufficient nutrients for the cell growth for mammalian cells such as Chinese hamster ovary (CHO) cells, and applying appropriate media is important in developing cell line and cell culture process with high productivity and quality.

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PMC4685411

The optimization of complex biotechnological production processes with approved Design of Experiment (DoE) methods is therefore time-consuming and cost-intensive.

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PMC11489351

Assays were run in technical duplicates and averaged for each data point.

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PMC9581083

Patients with symptoms such as fever due to warm-damp epidemic poisoning should be treated with substances that clear heat, detoxify and dredge the collaterals, dispel cold and dehumidify, so the appropriate TCM formulas are those that clear heat, detoxify dampness and relieve asthma as the core treatment method.

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PMC3164356

The CHO-K1 genome has homologs to all six human ST3Gal enzymes, which form α(2,3) linkages of sialic acid to galactose.

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PMC2944824

Briefly, following treatment cells were harvested and lysed using the Cytosol Extraction Buffer Mix with DTT and Protease Inhibitors, cells were incubated on ice for 10 min prior to being homogenized in a dounce homogenizer.

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PMC9429973

The most common sites of relapse were lymph nodes (3), soft tissue (3) and CNS (2).

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PMC9429973

Each journal´s website was screened, and we extracted data on the composition of the editorial board, including editors-in-chief and associate editors and excluded editorial board members with other roles which are not of editorial capacity.

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PMC10419319

Concerning cisplatin resistance, the dysregulated glycolytic pathway provides a survival advantage to resistant cancer cells.

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PMC11795610

HC: HC-067047, TRPV4 inhibitor.

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PMC10329074

There has been significant progress in the treatment of patients with ccRCC, with improved knowledge of disease biology and the introduction of targeted agents and immunotherapies (Atkins and Tannir 2018).

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PMC9429973

of Hematology, First Faculty of Medicine, Charles University, and General University Hospital, Prague, Czechia Background: The treatment of blast crisis of chronic myeloid leukaemia (BC-CML) remains difficult and the outcome of patients is poor.

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PMC7334607

We hypothesize that Ewing's sarcoma cell lines repeatedly exposed to standard chemotherapy will demonstrate divergent evolutionary paths between evolutionary replicates despite nearly identical experimental conditions and initial genotype.

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PMC8711270

Comparison of various γRV production methods.

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PMC11697065

E: Correlation of mRNA abundance with protein abundance for HC from clones expressing MonoAb2 and BisAb2.

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PMC11477621

The crude product was purified by silica gel chromatography to give the brown solid (77 mg, 20%).

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PMC11380329

= effect for drug a in combination E (cb) = effect for drug b in combination E (da) = effect of drug a alone E (db) = effect of drug b alone In an attempt to further clarify whether P treatment co-supplemented or not with Vit D affects the tumorigenicity of OVCAR4 cells, we investigated the expression of Ki67 which is ...

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PMC9275501

PMX/DCK-QCN-NE had good intestinal permeability and increased cell absorption of PMX/DCK and Que.

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PMC11661040

Western blot and immunohistochemistry (IHC) techniques were employed to detect the expression of relevant proteins.

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PMC11228511

NM ruptures and nuclear blebs are associated with an abnormal nuclear lamin meshwork in Lmnb1 and Zmpste24 SMCs. (

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PMC9577200

However, the results of this study support the view that graphene does not act as an antibacterial agent, so it may be used in biomedical nanotechnologies, such as facilitating surface-attached stem cells for orthopedics.

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PMC11531735

Comparison of tumor-free survival of ER121 treated groups ER121 high, ER121 low, Herceptin and PBS treated groups.

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PMC11361748

Of the 253 human genes homologs, 209 genes showed expression in the PSOR data set.

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PMC11506670

HCT116 provides the colorectal and epithelial background, but, similar to other commonly used colorectal cancer cell lines with mutations in either KRAS or PIK3CA, or both, it may mask the phenotypic effects of introduced mutations .

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PMC10033453

We found that the one mouse found moribund on day 6 had the highest level of ALT, and serum levels of ALB and ALP were elevated in a dose-dependent manner 15 days after treatment with VMG.

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PMC10854447

Molecular operating environment (MOE) software was used, as well as the crystal structure of the EGFR in complex with Erlotinib (PDB: 1M17).

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PMC8382973

PBS male rectum 1, 2; PBS female vagina 25, 26; gel male rectum 3, 4; gel female vagina 27, 28; 2% SFT gel male rectum 5, 6; 2% SFT gel female vagina 29, 30. (

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PMC9429973

Systemic mastocytosis with an associated hematologic neoplasm (SM-AHN) is both the most common and most heterogenous subtype of AdvSM.

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PMC11767725

These insights provide a promising framework for developing microbiome-based therapies to address a range of dermatological and systemic diseases.

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PMC11472639

Lymphocytes were identified in a SSC-A × FSC-A plot prior to the removal of doublets in a FSC-H × FSC-A plot.

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PMC11401358

Those without injured caudal fins were regarded as the control group, and those with injured caudal fins were regarded as the positive group.

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PMC6461034

To assess the global correlation of INKA with cell line drug efficacy data, we analyzed our cell line use cases (Fig 2) along with two cancer cell panels, with publicly available label‐free phosphoproteomics data (Piersma et al, 2015; van der Mijn et al, 2015; Humphrey et al, 2016) and associated drug IC50 data with dr...

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PMC11650848

Withdrawal after randomisation (n = 25) or reasons for exclusion from the intervention are indicated.

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PMC10547921

The payload in NIR-PIT drugs is not a cytotoxic substance, but a water-soluble phthalocyanine derivative (e.g., the silicon phthalocyanine derivative IR700 (IRDye700DX) (128)) (Fig. 22A).

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PMC11055510

B, C) RT-qPCR verified the effect of transfection of ov-circMAN1A2 in SKOV3 cells (B) or si-circMAN1A2 in A2780 cells on circMAN1A2 expression (C).

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PMC10452486

Spontaneous arthritis was also observed in HLA-B27 transgenic mice lacking B2m (HLA-B27+ B2m−/−) but not in HLA-B27+ B2m+/− mice.

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PMC11783017

However, the effect of ROS-responsive nanomedicines in promoting tumor regression is not ideal due to insufficient local ROS supply in tumors.

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PMC11731614

In this study, we provide the first comprehensive isolation and molecular characterization of KDEV protein and microRNA cargo in both RD and HFD mice.

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PMC11013014

All the synthesised compounds were evaluated and screened for their in vitro anti-proliferative activities against two cancer cell lines (HL60 and HCT116).

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PMC10988555

The pellet was resuspended in PBS 1× and centrifuged at 3000 × g for 5 min at 4 °C.

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PMC11527437

The most promising TCRs warrant testing in patients with KRAS G12V–positive cancers.

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PMC11739504

Nuclei were stained with DAPI (blue).

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PMC11488203

In more detail, the amount of viable GFP-positive cells was significantly reduced by about 50% after treatment of the MDA-MB-231 cancer cells with the different taxol-loaded exosomes or with 1 nM taxol.

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PMC11739484

Panel (B) displays box plots illustrating the promoter methylation levels of the MMPs in SKCM and control cell lines.

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PMC11679326

Previously, researchers linked the presence of β1,6-GlcNAc branches on N-glycans to tumor metastasis .

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PMC6461034

We explored implementation of an iBAQ procedure (Schwanhäusser et al, 2011) to correct for the number of phosphopeptides per kinase and the number of substrates per kinase.

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PMC11634027

To make Flp-out Dachs:GFP clones, animals were cultured at 18°C for 7 days, heat-shocked for 5 min at 35°C, and then wing discs were dissected out 18-24 h later.

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PMC10507284

At present, several studies have proven that the TROAP is elevated in glioma, liver cancer, prostate cancer, colon cancer, and other tumor tissues, and its expression level is negatively correlated with the survival prognosis of tumor patients. , , ,

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PMC9429973

Decreased level of IL8 and SOX9 normalized in remission.

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PMC11759751

The experimental procedure of chidamide on CD19 CAR T cells in preparation (A).

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PMC11697703

For miR-365 and miR-193b gain-of-function experiments, a CAG/H1 promoter plasmid was used to drive expression of GFP and mature miRs.

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PMC10154881

To demonstrate the antitumor effects of rMV‐SLAMblind in vitro, the cell viability of E.G‐7/N4 or B16/N4 and their parental cells was determined by WST‐1 assay after infection with rMV‐SLAMblind at an MOI of 2.

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PMC6742971

There is increasing evidence that low avidity T cells do not hinder their high avidity counterparts.

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PMC9429973

The median duration of exposure was 2.08 (range, 0.04-4.13) yrs with more than half (27 [56.3%]) of pts receiving treatment for ≥96 wks; the median daily dose intensity was 398.3 (range, 179-400) mg/day.

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PMC11703992

Given that pleiotropy between exposures and outcomes may introduce bias, a horizontal pleiotropy test was conducted on the eQTL and GWAS data.

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PMC9429973

No difference in the sensitivity to treatment with Bz was observed between mutated and wild-type patients.

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PMC11786767

D: Loss of Ki-67 reduces chromosome area.

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PMC11721587

Hh induces condensation of Fu and Ulk3 in the cytoplasm and primary cilium, respectively.

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PMC11258145

The lipid:curcumin ratios causing changes in the isotherms were significantly different for studied model mixtures being 8:1 for HL-60 cells and 64:1 for neuroblastoma cells (Fig. 1d,e).

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PMC11529598

J&K. The indicated cells (1 × 10) were subcutaneously injected into nude mice (n = 6) for xenograft assay.

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PMC11742231

Existing graph neural network (GNN) models for DRP encounter several limitations that hinder their performance.

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PMC10589262

One-way ANOVA with a post-hoc test was performed to compare multiple means (*p < 0.05, **p < 0.01, ***p < 0.001).

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PMC11742290

LGR5 silencing also reduced tumorigenesis in vivo using CRC and ovarian cancer models .

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PMC11679033

Obviously, to elucidate the apoptotic potentials of CIT and CBD, different methods and approaches have been used so far, which differ from each other in terms of sensitivity and the possibilities of elucidating the mechanisms underlying cell death.

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PMC11656380

Previous studies have shown that inhibition of NOTCH signaling induces cell-cycle arrest, apoptosis, and decreased proliferative capacity in a subset of T-ALL cell lines.

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PMC11040965

During the MGUS to MM transition, bone marrow becomes enriched in tumor plasma cells, as it is the primary site of their proliferation.

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PMC11661040

D-E) The CCK-8 assay was employed to assess the impact of CGREF1 knockdown on cell proliferation stability. (

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