OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11802855	To further validate the clinical relevance of CXCL7, we assessed its prognostic value in the Multiple Myeloma Research Foundation (MMRF) database, the largest publicly available dataset of MM patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11673902	These mechanical forces directly affect the mechanical properties of cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "mechanical", "forces", "directly", "affect", "the", "mechanical", "properties", "of", "...
PMC11021472	Based on all these potential interactions, it has become clear that the functionality of circRNAs is quite diverse.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Based", "on", "all", "these", ...
PMC10582049	CAF populations in the tumor microenvironment are diverse and characterized by different origins, spatial distribution, and markers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CAF", "populations", "in", "the",...
PMC10976516	Adenovirus and vaccinia virus are two examples of OVs that may be altered to carry transgenes (armed OVs), after which transgene products can be specifically delivered to the tumor microenvironment and further stimulate an anticancer immune response.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3035438	Taken together, these experiments demonstrated that the overexpression of the polyadenylation factor CstF-64 in CX13 cells induced the shutdown of chicken IgM expression and the relative increase of IgG synthesis, which resulted in a shift of the ratio of the concentration of IgG to IgM from 1:5 to about 4:1 and thus i...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11585565	At 24-hours post-transfection, immunofluorescent staining was performed at room temperature.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "24-hours", "post-transfection", ",", "immunofluorescent", "staining", "was", "performed", ...
PMC11720107	It is well documented that high levels of ROS often cause toxicity or initiate apoptosis .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "well", "documented", "that", "high", "levels", ...
PMC10669128	Several studies have been conducted on cell-derived xenograft (CDX) models to assess both the target therapy effectiveness and oncogenic activity in STSs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11190062	Proteasome subunits were among the upregulated genes in LPS-stimulated MM cells ( Supplementary Table 2 ), but TLR activation did not counteract the effect of bortezomib on proteasomal degradation efficacy ( Supplementary Figure 3A ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10976516	The cellular tropism of each virus dictates which tissues are most frequently infected.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cellular", "tropism", "of", "each", "virus", "dictates", "which", ...
PMC11247842	One salient difference is that there were two QTL on BTA1 for SCS but none for CM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "salient", "difference", "is", "that", ...
PMC11593084	As shown in Figure 4, PMab-117-mG2a induced ADCC against LN229/PDPN cells (17.3% cytotoxicity; p < 0.01) more effectively than the control mouse IgG2a (3.8% cytotoxicity).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9428827	The hIL-2 no-alpha mutein was produced in Escherichia coli, and the isolation of inclusion bodies and purification of the protein were performed as previously described (16).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4443654	We identify structurally variable domains between cell types and examine the underlying features to discover a general association with cell-type-specific enhancer activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "identi...
PMC9429973	Contemporarily, we observed a decrease of pS727-STAT3 (-35-50%) and pY694-STAT5 (-15-50%) and the significant reduction of phosphorylation on PI3K pathway,downregulating PDPK1, AKT, 4pEBP1 and pS6.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11267830	Recent research has shown that RBM39 mediates the increase in asparagine synthesis in liver cancer, leading to enhanced arginine uptake and the formation of a positive feedback loop to maintain high levels of arginine, thus promoting carcinogenic metabolism .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10582049	Gene ontology (GO) enrichment analysis indicates that CAFs from the FAPACTA2 cluster were mostly involved in processes associated with the deposition of ECM proteins and matrix remodeling (Fig. 3B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11519077	MB-CM group (treatment of IL-1β-induced Caco-2 cells with CM of menstrual blood–derived stem cells) The MTT assay was used to assess the effects of IL-1β on the viability of the Caco-2 cell line.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11747467	Data are presented as the mean ± SD. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "presented", "as", "the", "mean", "±", "SD", ".", "(" ] } ]
PMC11476004	The %T DNA value obtained for sick dogs was in many cases as high as in healthy dogs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "%", "T", "DNA", "val...
PMC11240448	Second, we introduced in silico perturbations to the dataset by removing individual analytes for the classification of cell subtypes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Second", ",", "we", "i...
PMC11536589	The MGST1 expression levels in MRTX1133-resistant PDAC cells treated with 1 µM LF3 or 0.2 µM PKF-118-310 for 48 h were measured by RT-qPCR detection. (	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11604015	For example, in 2021, Pan et al. demonstrated that a CAR-T cell product possesses a CD7-binding scFv domain and an ER-anchoring domain to retain CD7 proteins in the ER and achieve a surface CD7-negative phenotype .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11727062	The mechanism underlying this effect appears to involve the up-regulation of ATP1A1 expression in drug-resistant cells, enhancing their sensitivity to drug treatments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC9429973	IFM 2018-04 study is ongoing and longer follow-up is needed to evaluate safety and efficacy of the overall strategy with Dara-KRD induction and consolidation plus double transplant in this subset of HR patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11093197	As previously reported, oncogenically mutated H‐RAS transforms MCF10A and induces colony formation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O" ], "tokens": [ "As", "previously", "reported", ",", "oncogenically", "mutated", "H‐RAS",...
PMC11541409	These alterations mimic the cytosolic conformational rearrangement of wild-type KIT induced by stem cell factor (SCF) (Fig. 1A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "alt...
PMC8348645	To this 0.2 mL chloroform was added per 1 mL of TRIzol used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "this", "0.2", "mL", "chloroform", "was", "added", "per", "1", ...
PMC9118379	The workflow is shown in Figure S1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "workflow", "is", "shown", "in", "Figure", "S1", "." ] } ]
PMC9454852	The expression of GRP78, CHOP, and XBP1 were evaluated at both mRNA and protein levels.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "expression", "of", "GRP78", ",", "CH...
PMC9429973	Currently, there is no consensus on the treatment of ALL during coronavirus infection.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Currently", ",", "there", "is", "no", "consensus", "on", "the", ...
PMC11092382	Sophocarpine is a major ingredient in many traditional Chinese medicines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Sophocarpine", "is", "a", "major", "ingredient", "in", "many", "traditional", "Chinese", "medici...
PMC4443654	Sexton et al. showed that, in the Drosophila genome, topological structures termed physical domains could observably be clustered into distinct functional groups based on their average feature enrichments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10652261	Mp 169–170 °C.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Mp", "169–170", "°", "C", "." ] } ]
PMC11604768	TRE-MPRA libraries are available from Addgene under deposit number 82594.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TRE-MPRA", "libraries", "are", "available", "from", "Addgene", "under", "deposit", "number", "82...
PMC10329237	It was found that LOS and PFD as a single treatment can reverse the EMT process in BLM-treated A549 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "It", "was", "found"...
PMC11740907	To calculate the percentage of P5W30 that is enclosed inside nanoparticles, the difference between the total amount of P5W30 used and the amount of unbound P5W30 found in the aqueous phase of the supernatant was divided by the total amount of P5W30 used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11754784	Data are represented as mean ± s.d. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "represented", "as", "mean", "±", "s.d", ".", "(" ] } ]
PMC6337547	However, rosmarinic acid, protocatechuic aldehyde, and salvianolic acid A had no protective effects .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "rosmarinic", "acid", ",", "protocatech...
PMC11323699	Kaplan–Meier overall survival analysis comparing control mice (black), olaparib-vehicle mice (gray), olaparib-treated mice (orange), and mice treated sequentially with olaparib then TAX2 (green) is presented.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11545737	Recently, it has been found that Y. pseudotuberculosis infection increases glycolysis and reduces intracellular glucose levels in BMDMs and this leads to the glucose- and energy-responsive activation of AMPK, which in turn phosphorylates RIP1 during the caspase-8-mediated pyroptosis .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11680578	Percent ratio of red versus green fluorescence in SKOV-3 ovarian cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ "Percent", "ratio", "of", "red", "versus", "green", "fluorescence", "in", ...
PMC11759543	This suggests that ROS is not involved in doxorubicin-, vorinostat-, and their combination-induced cell death.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "suggests", "that", "ROS", "is", "no...
PMC3931643	This is consistent with the cytostatic effects of MLN0128 observed in all three cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "is", "consistent", "with", "the", "cytostatic", "ef...
PMC8873393	Briefly, cells were exposed to 10 J/m UV-C irradiation and incubated for the indicated time.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Briefly", ",", "cells", "were", "exposed", "to", ...
PMC6684588	Inhibitory activity of ACE-083 was measured in dual-luciferase reporter assays conducted with A204 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Inhibitory", "activity", "of", "ACE-083", "was", "measured", ...
PMC11464609	BoDV-1 (samples #15–23) are not specifically targeted by the panel, resulting in lower median viral genome coverage compared to conventional metagenomics (58% vs. 97%, Fig. 1a).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11354239	The expression of the TNFSF4 gene also correlated with the response of recurrent glioblastoma patients to autologous NK cell therapeutics, serving as a potential biomarker of responsiveness .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11172027	Membrane-associated carbonyl proteins are massively oxidatively modified proteins that are produced by radicals.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Membrane-associated", "carbonyl", "proteins", "are", "massively", "oxidatively", ...
PMC11087766	Protein import across the ChmA barrier is selective (1–4, 6, 10, 12).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Protein", "import", "across", "the", "ChmA", ...
PMC11748335	However, because of their shorter lengths, each short LOCK contains fewer peaks, leading to a total peak count in long LOCKs that is approximately five times greater than in short LOCKs or typical peaks (Fig. S1D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11638255	Serum data (excluding TGF-β) are presented as mean ± SEM, n = 4 (both groups) biological replicates, one independent experiment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11629461	Interestingly, the Cys‐containing motif of Cys‐Gly‐Cys in the catalytic NOX2 and Cys residues in P67 have been found to be important for NOX2‐P67 binding/association and NOX2 activation induced by oxidants. ,	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11782508	Furthermore, the strain’s antimicrobial activity will be evaluated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "the", "strain", "’s", "antimicrobial", "activity", "will", "be", "evaluated"...
PMC9592219	After initial treatment with 4% paraformaldehyde, the tumor tissue was embedded in paraffin and then sliced into 5 μm thick sections.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After",...
PMC10165258	This culture zone is constituted by a 2D array of 80 anchors (Figure 2A (ii)).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "culture", "zone", "is", ...
PMC9599726	Active YAP (nuclear and mixed location) was associated with a TFRC+++/++, while inactive YAP (cytoplasmic location) was associated with a TFRC+.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11337594	For the cell viability assay, 10,000 cells were seeded into 96-well plates and incubated overnight with the indicated experimental treatments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "the", "cel...
PMC11670407	Our results indicated that high GPX4 expression after cisplatin intervention was significantly regulated by OTULIN, as OTULIN deubiquitylated GPX4 to reduce its proteasomal degradation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10999934	The examination of the network module controlled by FBXO2 in the KEGG analysis indicated a strong presence of the PI3K-Akt signaling pathway, focal adhesion, and ECM-receptor interaction (Fig. 5B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11622247	This proved important for the detection of small amounts of the target RNA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "proved", "important", "for", "the", "detection", "of", "small", ...
PMC11755624	It binds to nucleophosmin (NPM), which is involved in responses to environmental stress and mRNA processing.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "binds", "to", "nucleophosmi...
PMC11171319	We cannot exclude that optimized immunohistochemistry and PCR techniques are required to detect it (reviewed in ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "can", "not", "exclude", ...
PMC11731161	On the next day, the sections were washed and subsequently incubated with Alexa Fluor® 488 Goat Anti-Rabbit IgG antibody for 1 h at room temperature.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11655536	The expression of LAMP1 was significantly increased in the HA group in both cell lines (Fig. 3F, G).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "expression", ...
PMC11805741	The gene expression analysis revealed a decrease in BCL-2 gene expression and an increase in BAX gene expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "gene", "expression", "analysis", ...
PMC9429973	These data suggest a model where the clinical activity of glofitamab may be dependent upon immune contexture in the tumor and PB at the start of treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8427838	p < 0.001.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "p", "<", "0.001", "." ] } ]
PMC9268620	The nuclear compaction that refers to the early stages of apoptosis was detectable in the cells treated with 1 and 3 µg/mL of nordamnacanthal.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11457557	Instead, a non-prior hypothesis is a more powerful approach for identifying gene association with a disease by screening the whole human genome.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Instead...
PMC8540611	These effects are associated with disruption of the mitochondrial membrane potential.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "effects", "are", "associated", "with", "disruption", "of", "the", "mitochondrial",...
PMC11453346	So far, only one H6PD interacting partner, 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1), has been reported.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "So", "far", ",", "only", "o...
PMC3675084	All cytotoxicity assays were performed in 96-well plates using a sulforhodamine B (SRB) colorimetric assay.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "cytotoxicity", "assays", "were", "performe...
PMC11244823	Noting that in contrast to the other three fragments, the gD1_160 fragment performed poorly in the above tests, the predicted 3D-structures of the four antigens were addressed by using the AlphaFold tool.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11298021	The expression of NOTCH1 was investigated in clinical samples, and finally, 15 out of 25 samples that were confirmed to be NOTCH1overexpressed were recruited for further analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11628309	The BE (2)-M17 cell line has also been used for the evaluation of the processes related to PD and has led to the identification of potential therapeutic targets.	[ { "tags": [ "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC9429973	2 underwent re-induction with FLAG-IDA remaining unresponsive.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "2", "underwent", "re-induction", "with", "FLAG-IDA", "remaining", "unresponsive", "." ] } ]
PMC9429973	Furthermore, hBD-2 treatment affected the intestinal microbial composition, including a shift towards higher abundance of Bacteroides species in hBD-2 treated compared to vehicle treated mice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10887351	In the same study by Rouget et al., the evidence of β3-ARs’ presence in the myometrium and their upregulation in pregnancy was strengthened by showing that they were the main subtype both in the human non-pregnant and pregnant myometrium (10- and 20-fold more abundant, respectively).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11786600	Contrarily, the PED2 and PED4 groups exhibited a darker blue color and denser arrangement of collagen fibers than the other groups, which suggests that the dressing used in these groups could enhance collagen deposition.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7887261	Gene constraint LoF o/e values developed with gnomAD: observed counts are based on sequencing data from gnomAD, expected counts are based on a mutational model that takes sequence context and coverage into account.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11753949	Hippocampi of P0-P1 C57BL/6J mice were dissected on ice in Hibernate-A media.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hippocampi", "of", "P0-P1", "C57BL/6J", "mice", "were", "dissected", "on", ...
PMC10203589	For example, ALDH1 (high) cells exhibit cancer stem cell (CSC) properties such as phenotypic diversity and in vivo tumorigenicity, and FGF18 expression is elevated in the ALDH (high) subpopulation in OC (100), thus FGF18 is significantly correlated with cancer stem cell properties in OC; And FGF18 is a differentially e...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11344246	Ovarian cancer can be classified into various histological subtypes including; sex cord stromal, germ cell, mixed cell type/miscellaneous and epithelial (3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11286266	Splicing was assessed by reverse transcription (RT)-PCR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Splicing", "was", "assessed", "by", "reverse", "transcription", "(RT)-PCR", "." ] } ]
PMC7812570	Similar to HAART, soluble bNAbs are not curative.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Similar", "to", "HAART", ",", "soluble", "bNAbs", "are", "not", "curative", "." ] } ]
PMC11033180	Next, the cellular distribution of Sema5A and Plexin A1/A2 receptors was studied in rat gut.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Next", ",", "the", "cellular", "distribution", "of", ...
PMC11186948	mRNA relative expression of TP53 in five controls (HD, grey bar) and patient LCL (#249, red bar). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9444294	One novel application in our study was to observe in situ fluorescent staining of fixed synovial sarcoma cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "novel", "application", "in", "o...
PMC5839394	As expected, we observed a concomitant down regulation of AKT, p-AKT, p62 and HSP90 expression and an up-regulation of ATG5, ATG7, LC3-II and beclin-1 in AgNPs-EPS treated cells, indicating a prominent mechanism of autophagic cell death. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11711345	Cells were treated in triplicate with cuminaldehyde 100 µM, for another 24 and 48h.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "treated", "in", "triplicate", "with", "cum...
PMC11721064	Furthermore, phosphorylation levels of PI3K and Akt were elevated approximately twofold (p < 0.001) and 2.5-fold (p < 0.001), respectively, in LN-KS KPCs compared to controls (Fig. 6A and 6B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3035438	In this report, we present a novel approach for the direct generation of chimeric human IgG in DT40 cell display libraries.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "this",...
PMC11300085	The proteins were visualized after incubation with enhanced chemiluminescence (ECL) (Thermo Fisher Scientific, Rockford, IL, USA) using ChemiDoc MP chemiluminescence gel imaging system (Bio-Rad, California, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7841067	Infected cells at a density of 1 × 10 cells/well were seeded into 96-well plates and incubated for 4 days.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Infected", "cells", "at", ...
PMC9143157	Moreover, the intracellular uptake of P-THP in all of the test cells were 2–10-fold less than THP, regardless of whether free THP or total THP (including contact P-THP) was measured.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8143558	It is worth noting that some of the plants are not known by members of various communities in which they are available.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", ...
PMC9429973	We previously reported that fixed-duration I+V provides deep, durable responses (Ghia et al, ASCO 2021; Wierda et al, J Clin Oncol 2021).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11679326	The main truncated O-glycan of carcinomas is the Tn antigen (GalNAcα-O-Ser/Thr), which predetermines their malignant phenotype and metastatic potential .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "main"...

PMC11802855

To further validate the clinical relevance of CXCL7, we assessed its prognostic value in the Multiple Myeloma Research Foundation (MMRF) database, the largest publicly available dataset of MM patients.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11673902

These mechanical forces directly affect the mechanical properties of cells .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "mechanical", "forces", "directly", "affect", "the", "mechanical", "properties", "of", "...

PMC11021472

Based on all these potential interactions, it has become clear that the functionality of circRNAs is quite diverse.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Based", "on", "all", "these", ...

PMC10582049

CAF populations in the tumor microenvironment are diverse and characterized by different origins, spatial distribution, and markers.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CAF", "populations", "in", "the",...

PMC10976516

Adenovirus and vaccinia virus are two examples of OVs that may be altered to carry transgenes (armed OVs), after which transgene products can be specifically delivered to the tumor microenvironment and further stimulate an anticancer immune response.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC3035438

Taken together, these experiments demonstrated that the overexpression of the polyadenylation factor CstF-64 in CX13 cells induced the shutdown of chicken IgM expression and the relative increase of IgG synthesis, which resulted in a shift of the ratio of the concentration of IgG to IgM from 1:5 to about 4:1 and thus i...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11585565

At 24-hours post-transfection, immunofluorescent staining was performed at room temperature.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "24-hours", "post-transfection", ",", "immunofluorescent", "staining", "was", "performed", ...

PMC11720107

It is well documented that high levels of ROS often cause toxicity or initiate apoptosis .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "well", "documented", "that", "high", "levels", ...

PMC10669128

Several studies have been conducted on cell-derived xenograft (CDX) models to assess both the target therapy effectiveness and oncogenic activity in STSs.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11190062

Proteasome subunits were among the upregulated genes in LPS-stimulated MM cells ( Supplementary Table 2 ), but TLR activation did not counteract the effect of bortezomib on proteasomal degradation efficacy ( Supplementary Figure 3A ).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10976516

The cellular tropism of each virus dictates which tissues are most frequently infected.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cellular", "tropism", "of", "each", "virus", "dictates", "which", ...

PMC11247842

One salient difference is that there were two QTL on BTA1 for SCS but none for CM.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "salient", "difference", "is", "that", ...

PMC11593084

As shown in Figure 4, PMab-117-mG2a induced ADCC against LN229/PDPN cells (17.3% cytotoxicity; p < 0.01) more effectively than the control mouse IgG2a (3.8% cytotoxicity).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9428827

The hIL-2 no-alpha mutein was produced in Escherichia coli, and the isolation of inclusion bodies and purification of the protein were performed as previously described (16).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC4443654

We identify structurally variable domains between cell types and examine the underlying features to discover a general association with cell-type-specific enhancer activity.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "identi...

PMC9429973

Contemporarily, we observed a decrease of pS727-STAT3 (-35-50%) and pY694-STAT5 (-15-50%) and the significant reduction of phosphorylation on PI3K pathway,downregulating PDPK1, AKT, 4pEBP1 and pS6.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11267830

Recent research has shown that RBM39 mediates the increase in asparagine synthesis in liver cancer, leading to enhanced arginine uptake and the formation of a positive feedback loop to maintain high levels of arginine, thus promoting carcinogenic metabolism .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10582049

Gene ontology (GO) enrichment analysis indicates that CAFs from the FAPACTA2 cluster were mostly involved in processes associated with the deposition of ECM proteins and matrix remodeling (Fig. 3B).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11519077

MB-CM group (treatment of IL-1β-induced Caco-2 cells with CM of menstrual blood–derived stem cells) The MTT assay was used to assess the effects of IL-1β on the viability of the Caco-2 cell line.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11747467

Data are presented as the mean ± SD. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "presented", "as", "the", "mean", "±", "SD", ".", "(" ] } ]

PMC11476004

The %T DNA value obtained for sick dogs was in many cases as high as in healthy dogs.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "%", "T", "DNA", "val...

PMC11240448

Second, we introduced in silico perturbations to the dataset by removing individual analytes for the classification of cell subtypes.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Second", ",", "we", "i...

PMC11536589

The MGST1 expression levels in MRTX1133-resistant PDAC cells treated with 1 µM LF3 or 0.2 µM PKF-118-310 for 48 h were measured by RT-qPCR detection. (

[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11604015

For example, in 2021, Pan et al. demonstrated that a CAR-T cell product possesses a CD7-binding scFv domain and an ER-anchoring domain to retain CD7 proteins in the ER and achieve a surface CD7-negative phenotype .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11727062

The mechanism underlying this effect appears to involve the up-regulation of ATP1A1 expression in drug-resistant cells, enhancing their sensitivity to drug treatments.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...

PMC9429973

IFM 2018-04 study is ongoing and longer follow-up is needed to evaluate safety and efficacy of the overall strategy with Dara-KRD induction and consolidation plus double transplant in this subset of HR patients.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11093197

As previously reported, oncogenically mutated H‐RAS transforms MCF10A and induces colony formation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O" ], "tokens": [ "As", "previously", "reported", ",", "oncogenically", "mutated", "H‐RAS",...

PMC11541409

These alterations mimic the cytosolic conformational rearrangement of wild-type KIT induced by stem cell factor (SCF) (Fig. 1A).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "alt...

PMC8348645

To this 0.2 mL chloroform was added per 1 mL of TRIzol used.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "this", "0.2", "mL", "chloroform", "was", "added", "per", "1", ...

PMC9118379

The workflow is shown in Figure S1.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "workflow", "is", "shown", "in", "Figure", "S1", "." ] } ]

PMC9454852

The expression of GRP78, CHOP, and XBP1 were evaluated at both mRNA and protein levels.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "expression", "of", "GRP78", ",", "CH...

PMC9429973

Currently, there is no consensus on the treatment of ALL during coronavirus infection.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Currently", ",", "there", "is", "no", "consensus", "on", "the", ...

PMC11092382

Sophocarpine is a major ingredient in many traditional Chinese medicines.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Sophocarpine", "is", "a", "major", "ingredient", "in", "many", "traditional", "Chinese", "medici...

PMC4443654

Sexton et al. showed that, in the Drosophila genome, topological structures termed physical domains could observably be clustered into distinct functional groups based on their average feature enrichments.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10652261

Mp 169–170 °C.

[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Mp", "169–170", "°", "C", "." ] } ]

PMC11604768

TRE-MPRA libraries are available from Addgene under deposit number 82594.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TRE-MPRA", "libraries", "are", "available", "from", "Addgene", "under", "deposit", "number", "82...

PMC10329237

It was found that LOS and PFD as a single treatment can reverse the EMT process in BLM-treated A549 cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "It", "was", "found"...

PMC11740907

To calculate the percentage of P5W30 that is enclosed inside nanoparticles, the difference between the total amount of P5W30 used and the amount of unbound P5W30 found in the aqueous phase of the supernatant was divided by the total amount of P5W30 used.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11754784

Data are represented as mean ± s.d. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "represented", "as", "mean", "±", "s.d", ".", "(" ] } ]

PMC6337547

However, rosmarinic acid, protocatechuic aldehyde, and salvianolic acid A had no protective effects .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "rosmarinic", "acid", ",", "protocatech...

PMC11323699

Kaplan–Meier overall survival analysis comparing control mice (black), olaparib-vehicle mice (gray), olaparib-treated mice (orange), and mice treated sequentially with olaparib then TAX2 (green) is presented.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11545737

Recently, it has been found that Y. pseudotuberculosis infection increases glycolysis and reduces intracellular glucose levels in BMDMs and this leads to the glucose- and energy-responsive activation of AMPK, which in turn phosphorylates RIP1 during the caspase-8-mediated pyroptosis .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11680578

Percent ratio of red versus green fluorescence in SKOV-3 ovarian cancer cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ "Percent", "ratio", "of", "red", "versus", "green", "fluorescence", "in", ...

PMC11759543

This suggests that ROS is not involved in doxorubicin-, vorinostat-, and their combination-induced cell death.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "suggests", "that", "ROS", "is", "no...

PMC3931643

This is consistent with the cytostatic effects of MLN0128 observed in all three cell lines.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "is", "consistent", "with", "the", "cytostatic", "ef...

PMC8873393

Briefly, cells were exposed to 10 J/m UV-C irradiation and incubated for the indicated time.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Briefly", ",", "cells", "were", "exposed", "to", ...

PMC6684588

Inhibitory activity of ACE-083 was measured in dual-luciferase reporter assays conducted with A204 cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Inhibitory", "activity", "of", "ACE-083", "was", "measured", ...

PMC11464609

BoDV-1 (samples #15–23) are not specifically targeted by the panel, resulting in lower median viral genome coverage compared to conventional metagenomics (58% vs. 97%, Fig. 1a).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11354239

The expression of the TNFSF4 gene also correlated with the response of recurrent glioblastoma patients to autologous NK cell therapeutics, serving as a potential biomarker of responsiveness .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11172027

Membrane-associated carbonyl proteins are massively oxidatively modified proteins that are produced by radicals.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Membrane-associated", "carbonyl", "proteins", "are", "massively", "oxidatively", ...

PMC11087766

Protein import across the ChmA barrier is selective (1–4, 6, 10, 12).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Protein", "import", "across", "the", "ChmA", ...

PMC11748335

However, because of their shorter lengths, each short LOCK contains fewer peaks, leading to a total peak count in long LOCKs that is approximately five times greater than in short LOCKs or typical peaks (Fig. S1D).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11638255

Serum data (excluding TGF-β) are presented as mean ± SEM, n = 4 (both groups) biological replicates, one independent experiment.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC11629461

Interestingly, the Cys‐containing motif of Cys‐Gly‐Cys in the catalytic NOX2 and Cys residues in P67 have been found to be important for NOX2‐P67 binding/association and NOX2 activation induced by oxidants. ,

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11782508

Furthermore, the strain’s antimicrobial activity will be evaluated.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "the", "strain", "’s", "antimicrobial", "activity", "will", "be", "evaluated"...

PMC9592219

After initial treatment with 4% paraformaldehyde, the tumor tissue was embedded in paraffin and then sliced into 5 μm thick sections.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After",...

PMC10165258

This culture zone is constituted by a 2D array of 80 anchors (Figure 2A (ii)).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "culture", "zone", "is", ...

PMC9599726

Active YAP (nuclear and mixed location) was associated with a TFRC+++/++, while inactive YAP (cytoplasmic location) was associated with a TFRC+.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC11337594

For the cell viability assay, 10,000 cells were seeded into 96-well plates and incubated overnight with the indicated experimental treatments.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "the", "cel...

PMC11670407

Our results indicated that high GPX4 expression after cisplatin intervention was significantly regulated by OTULIN, as OTULIN deubiquitylated GPX4 to reduce its proteasomal degradation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC10999934

The examination of the network module controlled by FBXO2 in the KEGG analysis indicated a strong presence of the PI3K-Akt signaling pathway, focal adhesion, and ECM-receptor interaction (Fig. 5B).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11622247

This proved important for the detection of small amounts of the target RNA.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "proved", "important", "for", "the", "detection", "of", "small", ...

PMC11755624

It binds to nucleophosmin (NPM), which is involved in responses to environmental stress and mRNA processing.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "binds", "to", "nucleophosmi...

PMC11171319

We cannot exclude that optimized immunohistochemistry and PCR techniques are required to detect it (reviewed in ).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "can", "not", "exclude", ...

PMC11731161

On the next day, the sections were washed and subsequently incubated with Alexa Fluor® 488 Goat Anti-Rabbit IgG antibody for 1 h at room temperature.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11655536

The expression of LAMP1 was significantly increased in the HA group in both cell lines (Fig. 3F, G).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "expression", ...

PMC11805741

The gene expression analysis revealed a decrease in BCL-2 gene expression and an increase in BAX gene expression.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "gene", "expression", "analysis", ...

PMC9429973

These data suggest a model where the clinical activity of glofitamab may be dependent upon immune contexture in the tumor and PB at the start of treatment.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8427838

p < 0.001.

[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "p", "<", "0.001", "." ] } ]

PMC9268620

The nuclear compaction that refers to the early stages of apoptosis was detectable in the cells treated with 1 and 3 µg/mL of nordamnacanthal.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11457557

Instead, a non-prior hypothesis is a more powerful approach for identifying gene association with a disease by screening the whole human genome.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Instead...

PMC8540611

These effects are associated with disruption of the mitochondrial membrane potential.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "effects", "are", "associated", "with", "disruption", "of", "the", "mitochondrial",...

PMC11453346

So far, only one H6PD interacting partner, 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1), has been reported.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "So", "far", ",", "only", "o...

PMC3675084

All cytotoxicity assays were performed in 96-well plates using a sulforhodamine B (SRB) colorimetric assay.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "cytotoxicity", "assays", "were", "performe...

PMC11244823

Noting that in contrast to the other three fragments, the gD1_160 fragment performed poorly in the above tests, the predicted 3D-structures of the four antigens were addressed by using the AlphaFold tool.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11298021

The expression of NOTCH1 was investigated in clinical samples, and finally, 15 out of 25 samples that were confirmed to be NOTCH1overexpressed were recruited for further analysis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11628309

The BE (2)-M17 cell line has also been used for the evaluation of the processes related to PD and has led to the identification of potential therapeutic targets.

[ { "tags": [ "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...

PMC9429973

2 underwent re-induction with FLAG-IDA remaining unresponsive.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "2", "underwent", "re-induction", "with", "FLAG-IDA", "remaining", "unresponsive", "." ] } ]

PMC9429973

Furthermore, hBD-2 treatment affected the intestinal microbial composition, including a shift towards higher abundance of Bacteroides species in hBD-2 treated compared to vehicle treated mice.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10887351

In the same study by Rouget et al., the evidence of β3-ARs’ presence in the myometrium and their upregulation in pregnancy was strengthened by showing that they were the main subtype both in the human non-pregnant and pregnant myometrium (10- and 20-fold more abundant, respectively).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11786600

Contrarily, the PED2 and PED4 groups exhibited a darker blue color and denser arrangement of collagen fibers than the other groups, which suggests that the dressing used in these groups could enhance collagen deposition.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7887261

Gene constraint LoF o/e values developed with gnomAD: observed counts are based on sequencing data from gnomAD, expected counts are based on a mutational model that takes sequence context and coverage into account.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11753949

Hippocampi of P0-P1 C57BL/6J mice were dissected on ice in Hibernate-A media.

[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hippocampi", "of", "P0-P1", "C57BL/6J", "mice", "were", "dissected", "on", ...

PMC10203589

For example, ALDH1 (high) cells exhibit cancer stem cell (CSC) properties such as phenotypic diversity and in vivo tumorigenicity, and FGF18 expression is elevated in the ALDH (high) subpopulation in OC (100), thus FGF18 is significantly correlated with cancer stem cell properties in OC; And FGF18 is a differentially e...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11344246

Ovarian cancer can be classified into various histological subtypes including; sex cord stromal, germ cell, mixed cell type/miscellaneous and epithelial (3).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC11286266

Splicing was assessed by reverse transcription (RT)-PCR.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Splicing", "was", "assessed", "by", "reverse", "transcription", "(RT)-PCR", "." ] } ]

PMC7812570

Similar to HAART, soluble bNAbs are not curative.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Similar", "to", "HAART", ",", "soluble", "bNAbs", "are", "not", "curative", "." ] } ]

PMC11033180

Next, the cellular distribution of Sema5A and Plexin A1/A2 receptors was studied in rat gut.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Next", ",", "the", "cellular", "distribution", "of", ...

PMC11186948

mRNA relative expression of TP53 in five controls (HD, grey bar) and patient LCL (#249, red bar). (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC9444294

One novel application in our study was to observe in situ fluorescent staining of fixed synovial sarcoma cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "novel", "application", "in", "o...

PMC5839394

As expected, we observed a concomitant down regulation of AKT, p-AKT, p62 and HSP90 expression and an up-regulation of ATG5, ATG7, LC3-II and beclin-1 in AgNPs-EPS treated cells, indicating a prominent mechanism of autophagic cell death. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11711345

Cells were treated in triplicate with cuminaldehyde 100 µM, for another 24 and 48h.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "treated", "in", "triplicate", "with", "cum...

PMC11721064

Furthermore, phosphorylation levels of PI3K and Akt were elevated approximately twofold (p < 0.001) and 2.5-fold (p < 0.001), respectively, in LN-KS KPCs compared to controls (Fig. 6A and 6B).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC3035438

In this report, we present a novel approach for the direct generation of chimeric human IgG in DT40 cell display libraries.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "this",...

PMC11300085

The proteins were visualized after incubation with enhanced chemiluminescence (ECL) (Thermo Fisher Scientific, Rockford, IL, USA) using ChemiDoc MP chemiluminescence gel imaging system (Bio-Rad, California, USA).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7841067

Infected cells at a density of 1 × 10 cells/well were seeded into 96-well plates and incubated for 4 days.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Infected", "cells", "at", ...

PMC9143157

Moreover, the intracellular uptake of P-THP in all of the test cells were 2–10-fold less than THP, regardless of whether free THP or total THP (including contact P-THP) was measured.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8143558

It is worth noting that some of the plants are not known by members of various communities in which they are available.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", ...

PMC9429973

We previously reported that fixed-duration I+V provides deep, durable responses (Ghia et al, ASCO 2021; Wierda et al, J Clin Oncol 2021).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11679326

The main truncated O-glycan of carcinomas is the Tn antigen (GalNAcα-O-Ser/Thr), which predetermines their malignant phenotype and metastatic potential .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "main"...