OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11700247	However, when both CART-19 and endogenous T cells were present, there was a significant elimination of the CD19, B220 subset within the A20 cells (Figure 7D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9219615	Cells that grow in suspension were evaluated generally after 48 h, whereas adherent cells were incubated for 72 h due to their slower doubling time.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11705067	Subsequently, cuproptosis-related genes and ccRCC differential genes were intersected to identify CDGs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Subsequently", ",", "cuproptosis-related", "genes", "and", "ccRCC", "differential...
PMC11548041	The loaded MNVs (tMNVs) were isolated by ultracentrifugation and resuspended in 500 μL of sterile PBS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "loaded", "MNVs", "(", "tMNVs", ...
PMC8336407	unit of measurement = µM)t: tert-Butyl hydroperoxide (t-BHP) E: Pyrus biossieriana Buhse leaves extractt 100 (t-BHP, concentration: 100 µM), t 150 (t-BHP, concentration: 150 µM), t 200 (t-BHP, concentration: 200 µM) The effect of pyrus biossieriana buhse leaf extract and t-BHP treatment on the cell viability of HepG2 c...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6222635	Since the wild resource is limited, researchers have developed a series of greenhouse cultivation methods to improve productivity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Since", "the", "wild", "resource"...
PMC9429973	Exclusion criteria include other AIHA subtypes, suspected secondary AIHA, splenectomy <3 months before randomization, and prior treatment with a PI3Kδ or pan-PI3K inhibitor for any indication.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11486946	The five non-EGFR-TKI compounds (broxyquinoline, daunorubicin, eltrombopag, sorafenib, and verteporfin) that decreased EGFR diffusion or clusters without EGF, reduced EGFR-dependent cell viability by downregulating EGFR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11752767	Nonetheless, its future use has become progressively brighter as the efficacy of CAR-NK cell therapy was elucidated in other solid tumor clinical trials.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11769516	The data from the time frame of 2001–2023 were used to search for information on mycotoxins and neurotoxicity, and data from 2011–2024 were used to search for information on neuroprotection.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11705862	Accordingly, while the mRNA levels (Fig. 6A) and total tau levels in cells remained unchanged (Fig. 6B, quantification in D), the levels of phosphorylated tau were significantly increased in cells with silenced CD59/ IRIS-1/ IRIS-2 (Fig. 6B, quantification in E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10788478	Morphologically, lung cancer cell lines are classified into sphere‐forming and adherent cells, with most SCLC cell lines cultivating as spheroid cultures.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Morphol...
PMC11476837	ML-385 inhibits interaction of NRF2 with sMAF (small musculoaponeurotic fibrosarcoma transcription factors) and down-regulates transcription of NRF2-dependent genes .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ML-385", "inhibits", "intera...
PMC10565698	LC cells (SK-Hep-1, BEL-7404, SMMC-7721, MHCC-97H, and HCCLM3) and a normal liver cell line (LO2) were obtained from Cell Bank/Stem Cell Bank, Chinese Academy of Sciences.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", ...
PMC11615828	We next evaluated whether the immobilization of VOIs functionally suppresses specific cargo delivery.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "next", "evaluated", "whether", "the", "immobilization", "of", "VOIs",...
PMC11098378	Transient siRNA knockdown was achieved by forward transfection of 80,000 LD652 cells with 8 pmol siRNA and 4 μL Cellfectin II (Gibco; S4 Table) according to the manufacturer’s protocol for 48 h prior to infection.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8357004	Finally, TSA had a more significant effect on gene expression in comparison to 5-Aza-CdR (P < 0.001).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Finally", ",", "TSA", ...
PMC9429973	The selection was conducted in murine erythroleukemia cells and human umbilical cord derived erythroid progenitor (HUDEP) cells, modified by knocking out all the human a-globin genes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11075223	Information related to Cimicifugae Rhizoma on literatures was collected from PubMed, Science Direct, Baidu Scholar, Google Scholar and the China National Knowledge Infrastructure (CNKI) from 1993 to 2023.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11448304	However, the underlying mechanism remains unclear.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "the", "underlying", "mechanism", "remains", "unclear", "." ] } ]
PMC11337594	In this study, we also found a slight upregulation of cyclin E1 after TER treatment, which was more significant after p53 knockout.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11471157	Thin sections were then examined using an electron microscope (JEM-2100, JEOL Ltd., Tokyo).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thin", "sections", "were", "then", "examined", ...
PMC9429973	Data of 74 of these patients are currently available for toxicity/efficacy analysis and updated results, including HR-QoL, will be presented during the EHA meeting.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9370419	DDB-1 can bind to other adaptor proteins and perform its E3 protein function.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "DDB-1", "can", "bind", "to", "other", "adaptor", "proteins", "and", "...
PMC11748335	We further investigated gene expression levels within long LOCKs compared to genes outside of any LOCKs (Fig. S4C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "further", "investigate...
PMC7348793	The amplification of these DNA samples with either Platinum Superfi or GoTaq G2 DNA polymerases resulted in essentially identical banding patterns (Figure 1, lines 5–7 and 12–14, respectively).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5916734	None of the tested genes showed any significant changes in its expression level, thus indicating that there are no substantial alterations in biosynthesis and protein processing in host cells secreting FIX with the achieved productivity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7351993	To precisely position the central microchannel for the SRS microscope and event detector, we developed an optics-microfluidics integration unit as shown in Supplementary Fig. 2c, 2d.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10565698	Compared to the NC group, the OE group showed augmented N-cadherin and vimentin levels.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Compared", "to", "the", "NC", "group", ",", "the", "O...
PMC11769522	Increased concentrations of CCL2 were observed after treatment with IFN-γ, TNF-α, and the IFN-γ/TNF-α mixture, and this mixture synergistically increased CCL2 production.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11467800	We employed confocal microscopy to monitor the progression of the injected cells and conducted a comprehensive examination on every cell present within the larvae, spanning from the yolk sac to the tail end.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5035325	Pulmonary metastases were measured as lung weight on both lung metastasis models: 3LL-model (c) and 4T1-model (g).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ "...
PMC9429973	We then evaluated the performance of the models with metrics including the receiver operating characteristic (ROC) area under the curve (AUC), accuracy, sensitivity/recall, specificity, positive predictive value (PPV)/precision, negative predictive value (NPV), and F1 score by 10-fold cross-validation in the training c...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9583612	By comparison, the average GHGRP-based inventory estimates in the three basins are 201, 432, and 97 scfh, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "By", "compar...
PMC11700523	p<0.01 vs. IS 0.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "p<0.01", "vs.", "IS", "0", "." ] } ]
PMC11719944	Immune tolerance is a crucial mechanism that prevents immune responses against the body’s own antigens.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Immune", "tolerance", "is", "a", "crucial", "mechanism...
PMC11470999	Representative immunohistochemistry (IHC) staining of CIP2A protein levels in subcutaneous tumors were treated with PF and temozolomide (TMZ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Representative", ...
PMC11770746	with different compounds every other day up to 4 doses.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "with", "different", "compounds", "every", "other", "day", "up", "to", "4", "doses", "." ...
PMC11512230	Given that primary sarcoma cell lines are more closely related to native sarcoma cells, we suggest that AltMV SPV show better binding efficacy on these cell lines (Figure 4B), which makes them a more promising delivery system.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	E. Crusoe, G. Ribeiro, K. Zanella, L. Perobelli, J. C. Saraiva FIlho, R. Magalhaes, R. Bittencourt, E. Souza, R. Centrone, N. Hamerschlak, R. Gaiolla, B. Gusmao, F. HIgashi, J. Farley, M. Capra, W. Braga, A. Hallack Neto, J. Vaz P Neto, C. Bonamin, C. Silva, J. T. Souto Filho, G. Martinez, E. Mattos, N. Castro, L. da S...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10582049	Tissue samples for histological assessment have been examined by pathologist and placed in a 10% neutral buffered formalin for 24 h at room temperature for fixation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11098378	Where indicated, complete media containing 0.05 μg/mL ActD or 50 nM Bort was added for the remainder of the infection.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Where", "indicated", ...
PMC11216402	gkm-SVM training produces similar weight vectors in the Mes-like, Intermediate, and Epi-like GC cell lines, resulting from the activation of similar sets of TFs. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11806106	Further, the calculated EC50 values were highly comparable (EC50 values of 445 nM (BRET) and 430 nM (FRET), Fig. 3C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11789597	The figure was created with BioRender.com/v03k780.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "figure", "was", "created", "with", "BioRender.com/v03k780", "." ] } ]
PMC9429973	Highly enriched in PEL cases (7/13), EPOR/JAK2 focal gains/amplifications were implicated in their extreme erythroid hyperplasia and associated with particularly poor prognosis, even compared to other Group-A cases, who had shorter survival than those in other groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11206502	However, more than half of the superficial bladder cancers will recur, with 10–40% resulting in metastatic outcomes .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "more", ...
PMC11411131	The SECIS was derived from Toxoplasma gondii SelT. Luc-491Sec exhibited a decrease in signal intensity upon treatment with different MeHg concentrations (0, 1, 2, 5, 10, or 20 µM for 24 h), resulting in a lower background than that of TrxR1-GFP.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11653533	Eventually, seeds and resin are the less studied plant parts; in particular, seeds of F. bengalensis and resin of F. carica have only been studied.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The association of sensitivity and resistance with gram negative and positive isolates was found statistically significant with Amikacin, Vancomycin, Fosfomycin and Ciprofloxacin Summary/Conclusion: Gram negative isolates were found prevalent in our study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11209164	The Vero cells were cultured in opaque white 96-well plates using 100 μL of complete DMEM supplemented with 30 mM HEPES until they reached a confluence of 95–100%.	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11519788	In contrast, in kidney cancer, SPOP is considered as an oncogene because it facilitates the degradation of the tumor suppressor PTEN 21.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11670954	Furthermore, BA promotes the proliferation of colon mucosal epithelial cells and increases the tightness of epithelial cell connections at subtoxic concentrations .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ...
PMC9599726	IHC was performed on ovarian cancer tissue, used as a positive control to validate TFRC antibody immunoreactivity (-ir), and on five primary GIST tissues with different clinicopathological features (Table S1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	For each milestone timepoint, treatment switches were counted if they occurred before the next milestone.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "each", "milestone", "timepoint", ",", "treatmen...
PMC6364197	Polycaprolactone (PCL) is used for 3D culture owing to its biochemical properties and compatibility.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Polycaprolactone", "(", "PCL", ")", "is", "used", ...
PMC10047551	For the control, we also included dSaCas9 fused to a catalytically dead TET1 domain (H1672Y and D1674A) (dSaCas9-dTET1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", ...
PMC11720808	The relative intensity of TLR4 bands in (C) were analyzed. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "relative", "intensity", "of", "TLR4", "bands", "in", "(", "C",...
PMC11738017	Of note, this inhibitory effect of sBCMA was not observed with OPM2_BCMA cells, consistent with the higher avidity of anti-BCMA CARs to membrane bound vs sBCMA (Figure 4C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8068766	OmicsIntegrator software’s Forest module was used to determine the subnetwork in the set of DEGs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "OmicsIntegrator", "software", "’s", "Forest", "module", ...
PMC11481779	For a standard use that does not require such thorough testing, one model is entirely sufficient.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "a", "standard", "use", "that", "does...
PMC9429973	In the ACM group (n=89), in addition to the standard examination, every week or more often using messengers, we did active medical monitoring of the patient’s symptoms and well-being, assessment of blood pressure and heart rate, control of cardioprotective medicines taken, correction of the therapy, calling patients fo...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11767582	Accordingly, our general strategy to selectively obtain the 1,5-geometry of the two aryl groups in triazoles 3 was to react A-ring azide 1 with B-ring magnesium acetylides of terminal alkynes 2, as previously reported (Scheme 2) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11768927	They also noted enhanced susceptibility in moderately VSV-resistant liposarcoma and bladder carcinoma cells with JAK1 inhibitor pretreatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "They", "also", "noted", "enhanced", "susceptibili...
PMC11367146	After removing duplicate genes, a total of 2577 genes related to OA were filtered out.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "removing", "duplicate", "genes", ",", "a", ...
PMC11244823	The aa-identity level between the two molecules amounts to 77% but the longest stretch of consecutive identical aa maps to the extracellular domain near the transmembrane region and ranges from aspartic acid 261 (D261) to threonine 299 (T299) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11528603	The level of activated caspase 3 was investigated by cleaved caspase 3 staining using anti-cleaved caspase 3 antibody (product number: 9661, Cell Signaling Technology).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9918897	In addition, the literature describes the ability of plasma proteins to form complexes with polyphenols .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", "the", "literature", "describes"...
PMC11552389	Finally, the colonies were washed with PBS to remove excess dye.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Finally", ",", "the", "colonies", "were", "washed", "with", "PBS", "to", "...
PMC11786156	Furthermore, DLBCL with high CD54 expression levels has been reported to show a good prognosis compared with CD54-negative cases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "DLBCL", ...
PMC9105697	Conclusions: Targeted NGS allows for highly sensitive tumor profiling and non-invasive detection of ctDNA in SS patients, enabling non-invasive monitoring of tumor dynamics.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11643491	The absorbance was measured at 540 nm using a plate reader (Synergy HT Multi-Mode Microplate Reader, BioTek, Shoreline, WA, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11583010	The buffer was then exchanged to 100 mmol/L KPO4 pH 8.0 before incubation at 37°C for 24 hours in the absence of oxygen to allow the maleimide to self-hydrolyze.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11767725	This shift in lipid mediator profiles perpetuates localized inflammation and delays resolution.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "shift", "in", "lipid", "mediator", "profiles", "perpetuates", "localized", ...
PMC11740573	P values ≤ 0.05 were considered statistically significant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P", "values", "≤", "0.05", "were", "considered", "statistically", "significant", "." ] } ]
PMC2614415	In this study we sought to determine if chemical inhibition of the Aurora kinase family using VE-465 could synergize with paclitaxel to induce apoptosis in paclitaxel-resistant and sensitive ovarian cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9031474	Compound 24 was more active than 2 suggesting that the C9 hydroxyl group leads to an increase in cytotoxicity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Compound", "24", "was", "more", ...
PMC11638288	Moreover, studies have indicated that alterations in NKp46 expression on NK cells following in vitro fertilization are associated with embryo implantation failure, highlighting the importance of maintaining a balanced level of NKp46 for embryo implantation .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11534377	The data indicate an increase in the apoptotic population at the 48-hour time point, especially when 5-Aza is combined with 2 Gy of IR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10440586	The concentration of d-glucose, 6-phosphofructose, and glyceric acid was up-regulated in glioma with highly expressed CD99, indicating that their glucose uptake was enhanced and more intermediates of glucose metabolism were accumulated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11588085	XIST could regulate SC-specific pathways through multiple mechanisms.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "XIST", "could", "regulate", "SC-specific", "pathways", "through", "multiple", "mechanisms", "." ] } ]
PMC9895440	Afterwards we washed and incubated them in serum-free cytokine-free medium (RPMI with other supplements as above but without serum, but with 0.1% BSA to reduce attachment) for 1 h at 37 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10421378	The samples (approximately 5–6 mg) were weighed into 20 µL aluminum pans (PerkinElmer, No. 0219–0062, Waltham, MA, USA) and hermetically sealed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11361748	Again, we found that the response to UVB as a second treatment entails an acceleration and increased amplitude of neutrophils in the dermis, and is manifested when UVB is administered at 24 h, but not 48 h, after the initial TPA Tx (Fig 1G and 1H).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11470999	The impact of CIP2A knockdown on the proliferation of melanoma cells in the MTT assay. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "impact", "of", "CIP2A", "knockdown", "on", ...
PMC2777936	To determine if either FZD5 or FZD7 were acting through JNK, the levels of activated-JNK in protein lystaes were examined from cells treated with siRNAs to FZD5 and FZD7.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4485786	Long-term cohorts were treated at least until day 95 post tumor inoculation before evaluation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Long-term", "cohorts", "were", "treated", "at", "least", "until", ...
PMC9429973	Image: Summary/Conclusion: FA is still a golden standard for screening NPM1 gene mutations in AML.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Image", ":", "Summary/Conclusion", ":", "FA", ...
PMC9884169	In addition, we also tested whether the knockdown of MCT4 could affect autophagy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", "we", "also", "tested", "whether", "the", ...
PMC11643491	Hence, for the cell uptake experiment, we used the oil-free method.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hence", ",", "for", "the", "cell", "uptake", "experiment", ",", "we",...
PMC11001582	Graph, mean ± s.e.m.,	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Graph", ",", "mean", "±", "s.e.m", ".", "," ] } ]
PMC5363531	This correlation mRNA-protein was not retained for SRC expression: SRC gene and protein expression levels were not associated and SRC protein, both total and phosphorylated forms, was higher in REN and MSTO compared to MPP89.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5600151	Dendrimers show a great potential, especially in the promising field of RNAi, which has not yet reached the market either.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Dendrimers", ...
PMC9429973	Approximately 130 patients (30 in Phase 1a, 100 in Phase 1b) will be enrolled and treated until disease progression or unacceptable toxicity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9611901	Besides collagen, proteoglycans, hyaluronic acid and smaller amounts of carbohydrates are also present in the reticular layer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Besides", "collagen", ",", "prote...
PMC11612315	Two-tailed unpaired t test (****p < 0.0001, compared with the saline group).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Two-tailed", "unpaired", "t", "te...
PMC9622879	Subsequently, the SS is run to create an optimized schedule for all DERs and devices of each home during a day, whereas the local energy trading manager is run to calculate local buying and selling prices.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8913139	Cell migration was found to be inhibited by miR-448 mimics and promoted by miR-448 inhibitor (P < 0.01, Figure 2(c)).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC6771295	When SIRT1 was silenced, drug treatment did not affect autophagy substantially compared to the respective scramble control (Figure 8B, compare bars 2, 3, and 4 to 6, 7, and 8, respectively).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11770130	The top-5 differentially detected ceramides in WATs and serum were presented at Fig. 3h, i. The expression of CerS5 and CerS6 was also unchanged in adipose tissues with the haploid depletion of CerS2 (Supplementary information, Fig. S5d).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11700247

However, when both CART-19 and endogenous T cells were present, there was a significant elimination of the CD19, B220 subset within the A20 cells (Figure 7D).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9219615

Cells that grow in suspension were evaluated generally after 48 h, whereas adherent cells were incubated for 72 h due to their slower doubling time.

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PMC11705067

Subsequently, cuproptosis-related genes and ccRCC differential genes were intersected to identify CDGs.

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PMC11548041

The loaded MNVs (tMNVs) were isolated by ultracentrifugation and resuspended in 500 μL of sterile PBS.

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PMC8336407

unit of measurement = µM)t: tert-Butyl hydroperoxide (t-BHP) E: Pyrus biossieriana Buhse leaves extractt 100 (t-BHP, concentration: 100 µM), t 150 (t-BHP, concentration: 150 µM), t 200 (t-BHP, concentration: 200 µM) The effect of pyrus biossieriana buhse leaf extract and t-BHP treatment on the cell viability of HepG2 c...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC6222635

Since the wild resource is limited, researchers have developed a series of greenhouse cultivation methods to improve productivity.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Since", "the", "wild", "resource"...

PMC9429973

Exclusion criteria include other AIHA subtypes, suspected secondary AIHA, splenectomy <3 months before randomization, and prior treatment with a PI3Kδ or pan-PI3K inhibitor for any indication.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11486946

The five non-EGFR-TKI compounds (broxyquinoline, daunorubicin, eltrombopag, sorafenib, and verteporfin) that decreased EGFR diffusion or clusters without EGF, reduced EGFR-dependent cell viability by downregulating EGFR.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11752767

Nonetheless, its future use has become progressively brighter as the efficacy of CAR-NK cell therapy was elucidated in other solid tumor clinical trials.

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PMC11769516

The data from the time frame of 2001–2023 were used to search for information on mycotoxins and neurotoxicity, and data from 2011–2024 were used to search for information on neuroprotection.

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PMC11705862

Accordingly, while the mRNA levels (Fig. 6A) and total tau levels in cells remained unchanged (Fig. 6B, quantification in D), the levels of phosphorylated tau were significantly increased in cells with silenced CD59/ IRIS-1/ IRIS-2 (Fig. 6B, quantification in E).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10788478

Morphologically, lung cancer cell lines are classified into sphere‐forming and adherent cells, with most SCLC cell lines cultivating as spheroid cultures.

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PMC11476837

ML-385 inhibits interaction of NRF2 with sMAF (small musculoaponeurotic fibrosarcoma transcription factors) and down-regulates transcription of NRF2-dependent genes .

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PMC10565698

LC cells (SK-Hep-1, BEL-7404, SMMC-7721, MHCC-97H, and HCCLM3) and a normal liver cell line (LO2) were obtained from Cell Bank/Stem Cell Bank, Chinese Academy of Sciences.

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PMC11615828

We next evaluated whether the immobilization of VOIs functionally suppresses specific cargo delivery.

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PMC11098378

Transient siRNA knockdown was achieved by forward transfection of 80,000 LD652 cells with 8 pmol siRNA and 4 μL Cellfectin II (Gibco; S4 Table) according to the manufacturer’s protocol for 48 h prior to infection.

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PMC8357004

Finally, TSA had a more significant effect on gene expression in comparison to 5-Aza-CdR (P < 0.001).

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PMC9429973

The selection was conducted in murine erythroleukemia cells and human umbilical cord derived erythroid progenitor (HUDEP) cells, modified by knocking out all the human a-globin genes.

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PMC11075223

Information related to Cimicifugae Rhizoma on literatures was collected from PubMed, Science Direct, Baidu Scholar, Google Scholar and the China National Knowledge Infrastructure (CNKI) from 1993 to 2023.

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PMC11448304

However, the underlying mechanism remains unclear.

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PMC11337594

In this study, we also found a slight upregulation of cyclin E1 after TER treatment, which was more significant after p53 knockout.

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PMC11471157

Thin sections were then examined using an electron microscope (JEM-2100, JEOL Ltd., Tokyo).

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PMC9429973

Data of 74 of these patients are currently available for toxicity/efficacy analysis and updated results, including HR-QoL, will be presented during the EHA meeting.

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PMC9370419

DDB-1 can bind to other adaptor proteins and perform its E3 protein function.

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PMC11748335

We further investigated gene expression levels within long LOCKs compared to genes outside of any LOCKs (Fig. S4C).

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PMC7348793

The amplification of these DNA samples with either Platinum Superfi or GoTaq G2 DNA polymerases resulted in essentially identical banding patterns (Figure 1, lines 5–7 and 12–14, respectively).

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PMC5916734

None of the tested genes showed any significant changes in its expression level, thus indicating that there are no substantial alterations in biosynthesis and protein processing in host cells secreting FIX with the achieved productivity.

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PMC7351993

To precisely position the central microchannel for the SRS microscope and event detector, we developed an optics-microfluidics integration unit as shown in Supplementary Fig. 2c, 2d.

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PMC10565698

Compared to the NC group, the OE group showed augmented N-cadherin and vimentin levels.

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PMC11769522

Increased concentrations of CCL2 were observed after treatment with IFN-γ, TNF-α, and the IFN-γ/TNF-α mixture, and this mixture synergistically increased CCL2 production.

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PMC11467800

We employed confocal microscopy to monitor the progression of the injected cells and conducted a comprehensive examination on every cell present within the larvae, spanning from the yolk sac to the tail end.

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PMC5035325

Pulmonary metastases were measured as lung weight on both lung metastasis models: 3LL-model (c) and 4T1-model (g).

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PMC9429973

We then evaluated the performance of the models with metrics including the receiver operating characteristic (ROC) area under the curve (AUC), accuracy, sensitivity/recall, specificity, positive predictive value (PPV)/precision, negative predictive value (NPV), and F1 score by 10-fold cross-validation in the training c...

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PMC9583612

By comparison, the average GHGRP-based inventory estimates in the three basins are 201, 432, and 97 scfh, respectively.

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PMC11700523

p<0.01 vs. IS 0.

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PMC11719944

Immune tolerance is a crucial mechanism that prevents immune responses against the body’s own antigens.

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PMC11470999

Representative immunohistochemistry (IHC) staining of CIP2A protein levels in subcutaneous tumors were treated with PF and temozolomide (TMZ).

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PMC11770746

with different compounds every other day up to 4 doses.

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PMC11512230

Given that primary sarcoma cell lines are more closely related to native sarcoma cells, we suggest that AltMV SPV show better binding efficacy on these cell lines (Figure 4B), which makes them a more promising delivery system.

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PMC9429973

E. Crusoe, G. Ribeiro, K. Zanella, L. Perobelli, J. C. Saraiva FIlho, R. Magalhaes, R. Bittencourt, E. Souza, R. Centrone, N. Hamerschlak, R. Gaiolla, B. Gusmao, F. HIgashi, J. Farley, M. Capra, W. Braga, A. Hallack Neto, J. Vaz P Neto, C. Bonamin, C. Silva, J. T. Souto Filho, G. Martinez, E. Mattos, N. Castro, L. da S...

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PMC10582049

Tissue samples for histological assessment have been examined by pathologist and placed in a 10% neutral buffered formalin for 24 h at room temperature for fixation.

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PMC11098378

Where indicated, complete media containing 0.05 μg/mL ActD or 50 nM Bort was added for the remainder of the infection.

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PMC11216402

gkm-SVM training produces similar weight vectors in the Mes-like, Intermediate, and Epi-like GC cell lines, resulting from the activation of similar sets of TFs. (

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PMC11806106

Further, the calculated EC50 values were highly comparable (EC50 values of 445 nM (BRET) and 430 nM (FRET), Fig. 3C).

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PMC11789597

The figure was created with BioRender.com/v03k780.

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PMC9429973

Highly enriched in PEL cases (7/13), EPOR/JAK2 focal gains/amplifications were implicated in their extreme erythroid hyperplasia and associated with particularly poor prognosis, even compared to other Group-A cases, who had shorter survival than those in other groups.

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PMC11206502

However, more than half of the superficial bladder cancers will recur, with 10–40% resulting in metastatic outcomes .

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PMC11411131

The SECIS was derived from Toxoplasma gondii SelT. Luc-491Sec exhibited a decrease in signal intensity upon treatment with different MeHg concentrations (0, 1, 2, 5, 10, or 20 µM for 24 h), resulting in a lower background than that of TrxR1-GFP.

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PMC11653533

Eventually, seeds and resin are the less studied plant parts; in particular, seeds of F. bengalensis and resin of F. carica have only been studied.

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PMC9429973

The association of sensitivity and resistance with gram negative and positive isolates was found statistically significant with Amikacin, Vancomycin, Fosfomycin and Ciprofloxacin Summary/Conclusion: Gram negative isolates were found prevalent in our study.

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PMC11209164

The Vero cells were cultured in opaque white 96-well plates using 100 μL of complete DMEM supplemented with 30 mM HEPES until they reached a confluence of 95–100%.

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PMC11519788

In contrast, in kidney cancer, SPOP is considered as an oncogene because it facilitates the degradation of the tumor suppressor PTEN 21.

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PMC11670954

Furthermore, BA promotes the proliferation of colon mucosal epithelial cells and increases the tightness of epithelial cell connections at subtoxic concentrations .

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PMC9599726

IHC was performed on ovarian cancer tissue, used as a positive control to validate TFRC antibody immunoreactivity (-ir), and on five primary GIST tissues with different clinicopathological features (Table S1).

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PMC9429973

For each milestone timepoint, treatment switches were counted if they occurred before the next milestone.

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PMC6364197

Polycaprolactone (PCL) is used for 3D culture owing to its biochemical properties and compatibility.

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PMC10047551

For the control, we also included dSaCas9 fused to a catalytically dead TET1 domain (H1672Y and D1674A) (dSaCas9-dTET1).

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PMC11720808

The relative intensity of TLR4 bands in (C) were analyzed. (

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PMC11738017

Of note, this inhibitory effect of sBCMA was not observed with OPM2_BCMA cells, consistent with the higher avidity of anti-BCMA CARs to membrane bound vs sBCMA (Figure 4C).

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PMC8068766

OmicsIntegrator software’s Forest module was used to determine the subnetwork in the set of DEGs.

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PMC11481779

For a standard use that does not require such thorough testing, one model is entirely sufficient.

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PMC9429973

In the ACM group (n=89), in addition to the standard examination, every week or more often using messengers, we did active medical monitoring of the patient’s symptoms and well-being, assessment of blood pressure and heart rate, control of cardioprotective medicines taken, correction of the therapy, calling patients fo...

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PMC11767582

Accordingly, our general strategy to selectively obtain the 1,5-geometry of the two aryl groups in triazoles 3 was to react A-ring azide 1 with B-ring magnesium acetylides of terminal alkynes 2, as previously reported (Scheme 2) .

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PMC11768927

They also noted enhanced susceptibility in moderately VSV-resistant liposarcoma and bladder carcinoma cells with JAK1 inhibitor pretreatment.

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PMC11367146

After removing duplicate genes, a total of 2577 genes related to OA were filtered out.

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PMC11244823

The aa-identity level between the two molecules amounts to 77% but the longest stretch of consecutive identical aa maps to the extracellular domain near the transmembrane region and ranges from aspartic acid 261 (D261) to threonine 299 (T299) .

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PMC11528603

The level of activated caspase 3 was investigated by cleaved caspase 3 staining using anti-cleaved caspase 3 antibody (product number: 9661, Cell Signaling Technology).

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PMC9918897

In addition, the literature describes the ability of plasma proteins to form complexes with polyphenols .

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PMC11552389

Finally, the colonies were washed with PBS to remove excess dye.

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PMC11786156

Furthermore, DLBCL with high CD54 expression levels has been reported to show a good prognosis compared with CD54-negative cases.

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PMC9105697

Conclusions: Targeted NGS allows for highly sensitive tumor profiling and non-invasive detection of ctDNA in SS patients, enabling non-invasive monitoring of tumor dynamics.

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PMC11643491

The absorbance was measured at 540 nm using a plate reader (Synergy HT Multi-Mode Microplate Reader, BioTek, Shoreline, WA, USA).

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PMC11583010

The buffer was then exchanged to 100 mmol/L KPO4 pH 8.0 before incubation at 37°C for 24 hours in the absence of oxygen to allow the maleimide to self-hydrolyze.

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PMC11767725

This shift in lipid mediator profiles perpetuates localized inflammation and delays resolution.

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PMC11740573

P values ≤ 0.05 were considered statistically significant.

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PMC2614415

In this study we sought to determine if chemical inhibition of the Aurora kinase family using VE-465 could synergize with paclitaxel to induce apoptosis in paclitaxel-resistant and sensitive ovarian cancer cells.

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PMC9031474

Compound 24 was more active than 2 suggesting that the C9 hydroxyl group leads to an increase in cytotoxicity.

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PMC11638288

Moreover, studies have indicated that alterations in NKp46 expression on NK cells following in vitro fertilization are associated with embryo implantation failure, highlighting the importance of maintaining a balanced level of NKp46 for embryo implantation .

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PMC11534377

The data indicate an increase in the apoptotic population at the 48-hour time point, especially when 5-Aza is combined with 2 Gy of IR.

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PMC10440586

The concentration of d-glucose, 6-phosphofructose, and glyceric acid was up-regulated in glioma with highly expressed CD99, indicating that their glucose uptake was enhanced and more intermediates of glucose metabolism were accumulated.

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PMC11588085

XIST could regulate SC-specific pathways through multiple mechanisms.

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PMC9895440

Afterwards we washed and incubated them in serum-free cytokine-free medium (RPMI with other supplements as above but without serum, but with 0.1% BSA to reduce attachment) for 1 h at 37 °C.

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PMC10421378

The samples (approximately 5–6 mg) were weighed into 20 µL aluminum pans (PerkinElmer, No. 0219–0062, Waltham, MA, USA) and hermetically sealed.

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PMC11361748

Again, we found that the response to UVB as a second treatment entails an acceleration and increased amplitude of neutrophils in the dermis, and is manifested when UVB is administered at 24 h, but not 48 h, after the initial TPA Tx (Fig 1G and 1H).

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PMC11470999

The impact of CIP2A knockdown on the proliferation of melanoma cells in the MTT assay. (

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PMC2777936

To determine if either FZD5 or FZD7 were acting through JNK, the levels of activated-JNK in protein lystaes were examined from cells treated with siRNAs to FZD5 and FZD7.

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PMC4485786

Long-term cohorts were treated at least until day 95 post tumor inoculation before evaluation.

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PMC9429973

Image: Summary/Conclusion: FA is still a golden standard for screening NPM1 gene mutations in AML.

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PMC9884169

In addition, we also tested whether the knockdown of MCT4 could affect autophagy.

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PMC11643491

Hence, for the cell uptake experiment, we used the oil-free method.

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PMC11001582

Graph, mean ± s.e.m.,

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PMC5363531

This correlation mRNA-protein was not retained for SRC expression: SRC gene and protein expression levels were not associated and SRC protein, both total and phosphorylated forms, was higher in REN and MSTO compared to MPP89.

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PMC5600151

Dendrimers show a great potential, especially in the promising field of RNAi, which has not yet reached the market either.

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PMC9429973

Approximately 130 patients (30 in Phase 1a, 100 in Phase 1b) will be enrolled and treated until disease progression or unacceptable toxicity.

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PMC9611901

Besides collagen, proteoglycans, hyaluronic acid and smaller amounts of carbohydrates are also present in the reticular layer.

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PMC11612315

Two-tailed unpaired t test (****p < 0.0001, compared with the saline group).

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PMC9622879

Subsequently, the SS is run to create an optimized schedule for all DERs and devices of each home during a day, whereas the local energy trading manager is run to calculate local buying and selling prices.

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PMC8913139

Cell migration was found to be inhibited by miR-448 mimics and promoted by miR-448 inhibitor (P < 0.01, Figure 2(c)).

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PMC6771295

When SIRT1 was silenced, drug treatment did not affect autophagy substantially compared to the respective scramble control (Figure 8B, compare bars 2, 3, and 4 to 6, 7, and 8, respectively).

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PMC11770130

The top-5 differentially detected ceramides in WATs and serum were presented at Fig. 3h, i. The expression of CerS5 and CerS6 was also unchanged in adipose tissues with the haploid depletion of CerS2 (Supplementary information, Fig. S5d).

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