OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC9429973	CHD4-/- models underwent functional studies; proliferation, cell cycle and protein expression assays were used to phenotype models before inducing DNA damage at a clinically relevant dose and reassessing cell response.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10956161	Mutation of the PRDX6 gene in a range of cancers (b).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mutation", "of", "the", "PRDX6", "gene", "in", "a", "range", "of", ...
PMC11705067	Functional analysis of differentially expressed genes positively or negatively correlated with both FDX1 and DLAT indicated that acetyl-CoA biosynthetic process and acetyl-CoA metabolic process were remarkably affected.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11549062	Similar results of protein level of Cleaved‐Caspase 3 were also detected according to the PI results (Figure 5C,D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Similar", "r...
PMC9429973	Results: A total of 126 patients were included.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "A", "total", "of", "126", "patients", "were", "included", "." ] } ]
PMC11001582	n = 3 (brain), 5 (spinal cord) mice per genotype; one-way ANOVA, Bonferroni’s multiple comparison.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "n", ...
PMC2193049	These residues, defined as anchor residues, were shown to form direct contacts with the MHC molecule.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "residues", ",", "defined", "a...
PMC9545474	P NMR (161 MHz, CDCl3): δ −7.84 ppm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P", "NMR", "(", "161", "MHz", ",", "CDCl3", "):", "δ", "−7.84", "ppm", "....
PMC5963610	Around 90% of all deaths related to cancer are the result of metastasis rather than primary tumors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Around", "90", "%", "of", "all", ...
PMC7987994	Solutions of ZnCl2 served as simulated extracts and we also used extracts of three types of Zn-based and Mg-based degradable metals.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Solutions", "of", ...
PMC11448304	Enrichment of upregulated modified proteins displayed enhancement in energy metabolism while quantitative proteomic results showed enrichment in transmembrane signaling transduction activities.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Enrichment", "of", ...
PMC11470999	Existing treatments have shown limited efficacy against MBM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Existing", "treatments", "have", "shown", "limited", "efficacy", "against", "MBM", "." ] } ]
PMC9817179	Here, we only focused on the specific residence times.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Here", ",", "we", "only", "focused", "on", "the", "specific", "residence", "times", "." ...
PMC9429973	Methods: The target population comprised newly diagnosed pts aged ≥ 60 years old unfit for intensive treatment, including those with secondary AML, with or without prior exposure to AZA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9516447	All pair-wise comparisons were analyzed by the two-tailed Student's t-test with unequal variance in Microsoft Excel.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "pair-wise", "comparisons", "were", "analyz...
PMC10291556	HeLa cells were seeded (1 × 10 cells/well) and grown in 12-well plates, treated with platinum agents, and diclofenac for 6 h. Lactate concentration in the culture medium was measured using a colorimetric Lactate Assay Kit (Sigma-Aldrich) following the manufacturer’s instructions.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Likewise, improvements in EORTC QLQ-C30 fatigue, appetite loss, nausea and vomiting, diarrhea, cognitive functioning and social functioning favored IVO+AZA over placebo+AZA at multiple timepoints.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11423992	The CD3/CD20 bsAbs mentioned above exhibit enhanced cytotoxicity as indicated by lower EC50 values, which may concurrently heighten adverse reactions in the bloodstream.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11277157	In analyzing all three experimental groups, we observed a large number of differentially expressed genes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "analyzing", "all", "three", "experimental", "gro...
PMC11033180	Borosilicate pipettes (glass capillaries GC150TF-10, Harvard apparatus, USA) used for recordings were prepared with a micropipette puller (PC-10, Narishige Co, LTD, Japan).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11429241	Easily forming 3D cultures, SKOV3 cells do not show any differences between different types of scaffolds.	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Easily", "forming", "3D", "cultures", ",...
PMC11648299	, BCC (b) cSCC (c) and CM (d) among 357 patients with Darier disease and 3581 controls.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ",", ...
PMC11046454	Apt-CAR, utilizing the programmable antigen recognition ability of aptamers, provided a nongenetic re-engineering platform for precise control and modulation of the T cell response against cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	In a stratified analysis combining the information on MRD and PET, the 2-yr PFS were; 96% for MRD/PET -/-, 71% for MRD/PET -/+, and 58% MRD/PET +/-.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9545714	If the linear trend was to continue, an additional 10 weeks of supplementation would have reduced TEWL to the same range as the low‐TEWL group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10976516	On the other hand, both preclinical investigations and clinical trials have demonstrated that anti-tumor therapy employing naturally oncolytic NDV is safe and efficacious.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11655536	These collectively support lysosome biogenesis is involved in the HA-induced cell death of MM cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "collectively", "support", "lysosome", "biogenesis", "is"...
PMC6160470	One microliter of the tested compound dissolved in DMSO with or without Na-orthovanadate (600 mM) was added to the membrane suspension.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", ...
PMC7841067	Additionally, knockdown of AKAP4 greatly decreased the protein expression of Shh as well as Smo, Ptc, and Gli-1 in ACT-1 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "token...
PMC10728535	Each column indicates ovarian samples.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", "column", "indicates", "ovarian", "samples", "." ] } ]
PMC9688728	CV for each FAME calculated for all technical repetitions and all time points did not exceed 3.3% (Supplementary Table S1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CV", ...
PMC11281366	Although our data on HIV-1-infected CEM-CD59_control or CEM-CD59_KO cells (Figure S4) may require more substantial analyses, particularly using several other anti-HIV-1 antibodies, these findings are collectively consistent with results obtained previously using the Ab-mediated blockade of CD59 , as well as evidence th...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11544122	Bars represent the mean ± SD from three-four independent experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Bars", "represent", "the", "mean", "±", "SD", "from", "three-four", "independent", "experiments"...
PMC5035325	Expression of both molecules was located on plasmatic membrane.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Expression", "of", "both", "molecules", "was", "located", "on", "plasmatic", "membrane", "." ] } ]
PMC6684588	administration of ACE-083 did not appreciably alter body weight or circulating levels of follicle-stimulating hormone (see Supplementary Fig. S3), whose secretion is inhibited by endogenous follistatin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11300639	c, d 786-O and A498 cells were transfected with indicated siRNAs for 48 h. Cells were harvested for western blotting (c) and RT-qPCR (d) assay.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11335267	TaqMan primers (Applied Biosystems, Alcobendas, Madrid, Spain) or SYBR Green detection (Applied Biosystems) with specific primers indicated in Supplementary Table 1 were used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11640115	In addition, some advanced HNCs tend to show necrosis because of a lack of blood flow in the center region of the tumor.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC8469018	Dulbecco’s phosphate-buffered saline (DPBS) was obtained from Mediatech, Inc. A Corning Subsidiary (Manassas, VA, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Dulbecc...
PMC11402217	Normalized protein expression of WB in 143B cells (E) and MG63 cells (F).(G) Fluro-4 AM detection of Ca dynamics in OS cells treated with XD23 in 12h.(H) ER staining in 143B cells treated with XD23.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11476666	Cells were labeled with 5 µg/mL Hoechst 33342 (Sigma Aldrich, St. Louis, IL, USA) for 90 min at 37 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11703992	A 21 cell clusters were obtained after PCA analysis, and 7 types of cells were identified by manual annotation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "21", "cell", "clu...
PMC5673060	All ratios were median-normalised and log2 transformed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "ratios", "were", "median-normalised", "and", "log2", "transformed", "." ] } ]
PMC11697703	Lentivirus packaging was provided by System Biosciences (Palo Alto, CA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lentivirus", "packaging", "was", "provided", "by", "System", "Biosciences", ...
PMC4395774	Murine studies at Cincinnati Children's Hospital Medical Center were conducted in accordance with Cincinnati Children's Hospital Medical Center approved protocol.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Murine", "st...
PMC10142392	The development of multi-arm polymers is a subfield of PCL-based macromolecules that has garnered significant attention.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "development", "of", "multi-arm", "polymers", "i...
PMC11190538	The first portion was kept as a control (C), while two portions were fortified with 150 and 300 mg free C-PC, respectively and stirred using the mixer to prepare T1 and T2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11244823	Similarly, 95% sensitivity and 100% specificity were calculated with gD1_180, whereas gD1_83 amounted to 100% sensitivity and 95% specificity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9684669	Consequently, ovarian cancer patients continue to be in need of a therapeutic for effectively overcoming MDR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Consequently", ",", "ovarian", "cancer", "patient...
PMC11361748	Single or dual exposures of naïve skin to 400 mJ/cm UVB radiation does not cause a significant infiltration of neutrophils (see Fig 1G).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11794588	The filtrate was then again evaporated using a rotary evaporator to obtain the dry extract.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "filtrate", "was", "then", "again", "evaporated", "us...
PMC11271800	Among them, PD-1 is an inhibitory co-receptor mainly expressed on T cells, and PD-1 can bind to PD-L1 on tumor cells to effectively inhibit T-cell activity, thus reducing T-cell recognition of tumor cells and allowing tumor cells to evade immune surveillance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The combination of flumatinib with ABT-199 has a synergistic effect on cell proliferation arrest and apoptosis of the cells, revealing the potential of the novel combination for therapy of Ph+ B-cell ALL.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Afterward, resorting to flow cytometry, the cell cycle was assessed using propidium iodide/RNAse, and the cell death was determined using Annexin V/7-AAD double staining as well as by optic microscopy (May-Grünwald-Giemsa staining).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6901583	d GIST882 cells stably expressing vector or BRD4 were treated with 10 μmol/l BAY11-7082 for 1 h. The levels of p-p65 (S536) and BRD4 were analyzed by Western blotting.	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11297139	Moving averages were applied when necessary.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moving", "averages", "were", "applied", "when", "necessary", "." ] } ]
PMC11711663	TrainingTestingGenderMale13364Female7013RaceEA162/AA36/Other50SmokingYes13058No7319AlcoholYes104/No99/AJCCStageI452II2911III3664IV93/TreatmentCRT20/CT4/RT13/Sx92/Sx + RT36/Sx + CRT36/Sx + CT2/StatusAlive10555Dead9822 Clinical characteristics summary.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TrainingTestingGenderMale13364Female7013RaceEA162/AA36/Other50SmokingYes13058No7319AlcoholYes104/No99/AJCCStageI452II2911III3664IV93/TreatmentCRT20/CT...
PMC3931643	Statistical analysis using a t-test (**p<0.01).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "analysis", "using", "a", "t-test", "(", "", "", "p<0.01", ")", "." ] ...
PMC9583612	Figure 5 shows the empirical distribution of emission event durations and wait times for all emission events identified by the spike detection algorithm using a background-corrected amplitude threshold of 20 parts per million (ppm).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11786600	To improve the conformability of wound dressings to irregularly shaped wounds, a portable electrospinning device was used to perform in situ electrospinning at the wound site to prepare wound dressings to protect the wound while promoting wound healing.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10898159	Epigenetic modifications of histones, including methylation, phosphorylation, ubiquitination and acetylation, are the key processes for genes expression in GIST oncogenesis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11585565	Fluorescent signals corresponding to the FLAG-tagged WT and all mutants were detected on the plasma membrane of transfected HEK293 cells (Fig. 2e, Supplementary Figure S2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", ...
PMC11765988	For instance, in DISR, certain drugs (e.g., immune checkpoint inhibitors [ICIs]) increase the risk of sarcoidosis in “susceptible” individuals .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8873393	For RNA isolation from different fractions, TRIzol reagent was added directly to the cytoplasmic extract and RNA was isolated according the manufacturer’s instruction.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	All secondary causes were ruled out, again.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "secondary", "causes", "were", "ruled", "out", ",", "again", "." ] } ]
PMC11243198	Our study aimed to identify novel GLI1 inhibitors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Our", "study", "aimed", "to", "identify", "novel", "GLI1", "inhibitors", "." ] } ]
PMC11023271	It is unclear if these mutations contribute to the lower level of RIPK4 mRNA observed in SCC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "unclear", "if", "these", "mutat...
PMC11129910	HMEC 5.6 RAB25- Clone#5 cells show 70% wound closure at the end of 24 hours, confirming the increased capacity of the cells to migrate.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11033180	F, F′) Higher magnification of the boxed regions in E, E′ illustrates the pericellular Plexin A1 labeling.(G and G′) Double immunolabeling for Plexin A2 (green) and Hu (red) in the myenteric plexus of rat distal colon.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11011837	The results shown in Figure 6 highlight the main lipid molecular species with differences in expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "results", "shown", "in", "Figure", "6", "...
PMC11762280	P < 0.001.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "P", "<", "0.001", "." ] } ]
PMC11777207	Unpaired Student’s t tests and one-way analysis of variance (ANOVA) were used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Unpaired", "Student", "’s", "t", "tests", "and", "one-way",...
PMC11320084	Relative expression was calculated using the 2 method with glyceraldehyde 3‐phosphate dehydrogenase (GAPDH) as an internal control.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Relative", "expression", "was", "...
PMC11657744	Cells were transfected with Cep89 or Fbf1-specific siRNAs and then treated with serum for 12 h to induce disassembly.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "transfected", "w...
PMC9429973	The use of G-CSF therapy has radically changed these patients’ outlook.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "use", "of", "G-CSF", "therapy", "has", "radically", "changed", "these", ...
PMC11519583	Furthermore, enhanced MP proliferation by glycerol injection into the TA muscles was markedly suppressed in Ror2 cKO mice compared with that in control mice (Fig. 3j–l).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11746942	These findings collectively demonstrate that targeting the S1PR3–Src–STAT3 axis through selective S1PR3 antagonism effectively alleviates psoriasis-like inflammation (Fig. 8).Fig.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "fin...
PMC11792888	In contrast, both NSCLC cell lines showed a significant accumulation of cells in the G2/M phase after incubation with 1.36 mg/mL of scorpion venom, from 13.62 ± 3.3% to 29.29 ± 4.54% for A549 and from 13.41 ± 4.22% to 25.81 ± 9.03% for NCIH460 cells (Figures 2 C and 2D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4659567	The yields were 60–80%. [	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "yields", "were", "60–80", "%", ".", "[" ] } ]
PMC11787355	Transfection was performed with Fugene HD transfection reagent (#E2312, Promega) following the manufacture instructions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Transfection", "was", "performed", "with", ...
PMC10482220	The association could be due to binding to G3BP partners or to direct G3BP self-association.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "association", "could", "be", "due", "to", "binding",...
PMC9844987	To simultaneously capture the spread of TSSs and their relative frequencies compared to total RNA expression within a promoter, we considered a width-normalized Shannon entropy as a measure of TSS positional dispersion (Hoskins et al., 2011).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10996034	Imiquimod facilitates chemoresistance via the upregulation of MMP1, and RNA interference targeting ZYX reduces tumor cell HN12 resistance to cisplatin (DDP) (21,22).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6461034	Repeat the above washing procedure with IP buffer once.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Repeat", "the", "above", "washing", "procedure", "with", "IP", "buffer", "once", "." ] } ]
PMC11283030	First, we performed CCK-8 assay to evaluate the effect of ACLY on proliferation of ccRCC cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "First", ",", "we", "performed", "CCK-8", "a...
PMC11632064	Glycolytic reserve in human melanoma cell lines. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Glycolytic", "reserve", "in", "human", "melanoma", "cell", "lines", ".", "(" ] } ]
PMC7342409	Compared with the GIST882 imatinib-resistant group, the phosphorylation level in the imatinib group and the combination group was significantly lower (p<0.05), and the phosphorylation level in the CQ group was significantly higher (p<0.05).	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9878278	Gene expression of IFNB1 was determined in Activin A exposed SC at 48 hpi using qRT-PCR. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Gene", "expression", "of", "IFNB1", "was", ...
PMC11228511	The expression of progerin in genetically modified mice triggers disease phenotypes similar to those in children with HGPS (e.g., skeletal abnormalities, osteoporosis, alopecia, vascular disease, sclerodermatous changes in the skin) (4–6).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11119602	The release of cytochrome C through BAX oligomeric pores formed in the mitochondrial membrane is the key event initiating the apoptotic cascade (Figure 8).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11594074	DNMT1 is a large protein with multiple domains, which primarily targets hemi-methylated DNA and is therefore strongly associated with methylation after replication as opposed to de novo methylation, which is catalyzed mainly by DNMT3A and 3B .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10440586	The data from the GLASS project were extracted from the synapse repositories (https://www.synapse.org/).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "data", "from", "the", "GLASS", "project", "were", ...
PMC9275501	The mechanism was related to ROS, and the content of ROS was positively correlated with the inhibition of cell proliferation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mechanism", ...
PMC11394112	The MISTRG and MISTRG6 strains were not commercially available.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "MISTRG", "and", "MISTRG6", "strains", "were", "not", "commercially", "available", "." ] } ]
PMC9429973	Methods: Retrospective evaluation of patients diagnosed with aPTT between 2009 and 2019 in a terciary center.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Methods", ":", "Retrospective", "evaluation", "of...
PMC10674574	However, the documents proving the authenticity of the Caco-2 cell line are not strictly specified and are subject to the requirements of the relevant regulatory authority.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11300085	However, chemerin did not affect invasion of OVCAR-3 cells at different doses (Figure 2(d)).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "chemerin", "did", ...
PMC9878562	Cell migration was calculated as described above.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "migration", "was", "calculated", "as", "described", "above", "." ] } ]
PMC9429973	Analysis of bone marrow (BM) biopsies of 15 consecutive APL patients at diagnosis, revealed a homogeneous staining for BCL2 in all cases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11502443	However, tirzepatide makes an additional hydrogen bond with and arginine residue (R190) in the GIP receptor, which is hypothesized to facilitate changes in G protein binding affinity and signaling (Sun et al., 2022).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

CHD4-/- models underwent functional studies; proliferation, cell cycle and protein expression assays were used to phenotype models before inducing DNA damage at a clinically relevant dose and reassessing cell response.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10956161

Mutation of the PRDX6 gene in a range of cancers (b).

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PMC11705067

Functional analysis of differentially expressed genes positively or negatively correlated with both FDX1 and DLAT indicated that acetyl-CoA biosynthetic process and acetyl-CoA metabolic process were remarkably affected.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11549062

Similar results of protein level of Cleaved‐Caspase 3 were also detected according to the PI results (Figure 5C,D).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Similar", "r...

PMC9429973

Results: A total of 126 patients were included.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "A", "total", "of", "126", "patients", "were", "included", "." ] } ]

PMC11001582

n = 3 (brain), 5 (spinal cord) mice per genotype; one-way ANOVA, Bonferroni’s multiple comparison.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "n", ...

PMC2193049

These residues, defined as anchor residues, were shown to form direct contacts with the MHC molecule.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "residues", ",", "defined", "a...

PMC9545474

P NMR (161 MHz, CDCl3): δ −7.84 ppm.

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PMC5963610

Around 90% of all deaths related to cancer are the result of metastasis rather than primary tumors.

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PMC7987994

Solutions of ZnCl2 served as simulated extracts and we also used extracts of three types of Zn-based and Mg-based degradable metals.

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PMC11448304

Enrichment of upregulated modified proteins displayed enhancement in energy metabolism while quantitative proteomic results showed enrichment in transmembrane signaling transduction activities.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Enrichment", "of", ...

PMC11470999

Existing treatments have shown limited efficacy against MBM.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Existing", "treatments", "have", "shown", "limited", "efficacy", "against", "MBM", "." ] } ]

PMC9817179

Here, we only focused on the specific residence times.

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PMC9429973

Methods: The target population comprised newly diagnosed pts aged ≥ 60 years old unfit for intensive treatment, including those with secondary AML, with or without prior exposure to AZA.

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PMC9516447

All pair-wise comparisons were analyzed by the two-tailed Student's t-test with unequal variance in Microsoft Excel.

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PMC10291556

HeLa cells were seeded (1 × 10 cells/well) and grown in 12-well plates, treated with platinum agents, and diclofenac for 6 h. Lactate concentration in the culture medium was measured using a colorimetric Lactate Assay Kit (Sigma-Aldrich) following the manufacturer’s instructions.

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PMC9429973

Likewise, improvements in EORTC QLQ-C30 fatigue, appetite loss, nausea and vomiting, diarrhea, cognitive functioning and social functioning favored IVO+AZA over placebo+AZA at multiple timepoints.

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PMC11423992

The CD3/CD20 bsAbs mentioned above exhibit enhanced cytotoxicity as indicated by lower EC50 values, which may concurrently heighten adverse reactions in the bloodstream.

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PMC11277157

In analyzing all three experimental groups, we observed a large number of differentially expressed genes.

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PMC11033180

Borosilicate pipettes (glass capillaries GC150TF-10, Harvard apparatus, USA) used for recordings were prepared with a micropipette puller (PC-10, Narishige Co, LTD, Japan).

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PMC11429241

Easily forming 3D cultures, SKOV3 cells do not show any differences between different types of scaffolds.

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PMC11648299

, BCC (b) cSCC (c) and CM (d) among 357 patients with Darier disease and 3581 controls.

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PMC11046454

Apt-CAR, utilizing the programmable antigen recognition ability of aptamers, provided a nongenetic re-engineering platform for precise control and modulation of the T cell response against cancer cells.

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PMC9429973

In a stratified analysis combining the information on MRD and PET, the 2-yr PFS were; 96% for MRD/PET -/-, 71% for MRD/PET -/+, and 58% MRD/PET +/-.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9545714

If the linear trend was to continue, an additional 10 weeks of supplementation would have reduced TEWL to the same range as the low‐TEWL group.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC10976516

On the other hand, both preclinical investigations and clinical trials have demonstrated that anti-tumor therapy employing naturally oncolytic NDV is safe and efficacious.

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PMC11655536

These collectively support lysosome biogenesis is involved in the HA-induced cell death of MM cells.

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PMC6160470

One microliter of the tested compound dissolved in DMSO with or without Na-orthovanadate (600 mM) was added to the membrane suspension.

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PMC7841067

Additionally, knockdown of AKAP4 greatly decreased the protein expression of Shh as well as Smo, Ptc, and Gli-1 in ACT-1 cells.

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PMC10728535

Each column indicates ovarian samples.

[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", "column", "indicates", "ovarian", "samples", "." ] } ]

PMC9688728

CV for each FAME calculated for all technical repetitions and all time points did not exceed 3.3% (Supplementary Table S1).

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PMC11281366

Although our data on HIV-1-infected CEM-CD59_control or CEM-CD59_KO cells (Figure S4) may require more substantial analyses, particularly using several other anti-HIV-1 antibodies, these findings are collectively consistent with results obtained previously using the Ab-mediated blockade of CD59 , as well as evidence th...

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PMC11544122

Bars represent the mean ± SD from three-four independent experiments.

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PMC5035325

Expression of both molecules was located on plasmatic membrane.

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PMC6684588

administration of ACE-083 did not appreciably alter body weight or circulating levels of follicle-stimulating hormone (see Supplementary Fig. S3), whose secretion is inhibited by endogenous follistatin.

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PMC11300639

c, d 786-O and A498 cells were transfected with indicated siRNAs for 48 h. Cells were harvested for western blotting (c) and RT-qPCR (d) assay.

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PMC11335267

TaqMan primers (Applied Biosystems, Alcobendas, Madrid, Spain) or SYBR Green detection (Applied Biosystems) with specific primers indicated in Supplementary Table 1 were used.

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PMC11640115

In addition, some advanced HNCs tend to show necrosis because of a lack of blood flow in the center region of the tumor.

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PMC8469018

Dulbecco’s phosphate-buffered saline (DPBS) was obtained from Mediatech, Inc. A Corning Subsidiary (Manassas, VA, USA).

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PMC11402217

Normalized protein expression of WB in 143B cells (E) and MG63 cells (F).(G) Fluro-4 AM detection of Ca dynamics in OS cells treated with XD23 in 12h.(H) ER staining in 143B cells treated with XD23.

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PMC11476666

Cells were labeled with 5 µg/mL Hoechst 33342 (Sigma Aldrich, St. Louis, IL, USA) for 90 min at 37 °C.

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PMC11703992

A 21 cell clusters were obtained after PCA analysis, and 7 types of cells were identified by manual annotation.

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PMC5673060

All ratios were median-normalised and log2 transformed.

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PMC11697703

Lentivirus packaging was provided by System Biosciences (Palo Alto, CA).

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PMC4395774

Murine studies at Cincinnati Children's Hospital Medical Center were conducted in accordance with Cincinnati Children's Hospital Medical Center approved protocol.

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PMC10142392

The development of multi-arm polymers is a subfield of PCL-based macromolecules that has garnered significant attention.

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PMC11190538

The first portion was kept as a control (C), while two portions were fortified with 150 and 300 mg free C-PC, respectively and stirred using the mixer to prepare T1 and T2.

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PMC11244823

Similarly, 95% sensitivity and 100% specificity were calculated with gD1_180, whereas gD1_83 amounted to 100% sensitivity and 95% specificity.

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PMC9684669

Consequently, ovarian cancer patients continue to be in need of a therapeutic for effectively overcoming MDR.

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PMC11361748

Single or dual exposures of naïve skin to 400 mJ/cm UVB radiation does not cause a significant infiltration of neutrophils (see Fig 1G).

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PMC11794588

The filtrate was then again evaporated using a rotary evaporator to obtain the dry extract.

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PMC11271800

Among them, PD-1 is an inhibitory co-receptor mainly expressed on T cells, and PD-1 can bind to PD-L1 on tumor cells to effectively inhibit T-cell activity, thus reducing T-cell recognition of tumor cells and allowing tumor cells to evade immune surveillance.

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PMC9429973

The combination of flumatinib with ABT-199 has a synergistic effect on cell proliferation arrest and apoptosis of the cells, revealing the potential of the novel combination for therapy of Ph+ B-cell ALL.

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PMC9429973

Afterward, resorting to flow cytometry, the cell cycle was assessed using propidium iodide/RNAse, and the cell death was determined using Annexin V/7-AAD double staining as well as by optic microscopy (May-Grünwald-Giemsa staining).

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PMC6901583

d GIST882 cells stably expressing vector or BRD4 were treated with 10 μmol/l BAY11-7082 for 1 h. The levels of p-p65 (S536) and BRD4 were analyzed by Western blotting.

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PMC11297139

Moving averages were applied when necessary.

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PMC11711663

TrainingTestingGenderMale13364Female7013RaceEA162/AA36/Other50SmokingYes13058No7319AlcoholYes104/No99/AJCCStageI452II2911III3664IV93/TreatmentCRT20/CT4/RT13/Sx92/Sx + RT36/Sx + CRT36/Sx + CT2/StatusAlive10555Dead9822 Clinical characteristics summary.

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PMC3931643

Statistical analysis using a t-test (**p<0.01).

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PMC9583612

Figure 5 shows the empirical distribution of emission event durations and wait times for all emission events identified by the spike detection algorithm using a background-corrected amplitude threshold of 20 parts per million (ppm).

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PMC11786600

To improve the conformability of wound dressings to irregularly shaped wounds, a portable electrospinning device was used to perform in situ electrospinning at the wound site to prepare wound dressings to protect the wound while promoting wound healing.

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PMC10898159

Epigenetic modifications of histones, including methylation, phosphorylation, ubiquitination and acetylation, are the key processes for genes expression in GIST oncogenesis.

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PMC11585565

Fluorescent signals corresponding to the FLAG-tagged WT and all mutants were detected on the plasma membrane of transfected HEK293 cells (Fig. 2e, Supplementary Figure S2).

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PMC11765988

For instance, in DISR, certain drugs (e.g., immune checkpoint inhibitors [ICIs]) increase the risk of sarcoidosis in “susceptible” individuals .

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PMC8873393

For RNA isolation from different fractions, TRIzol reagent was added directly to the cytoplasmic extract and RNA was isolated according the manufacturer’s instruction.

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PMC9429973

All secondary causes were ruled out, again.

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PMC11243198

Our study aimed to identify novel GLI1 inhibitors.

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PMC11023271

It is unclear if these mutations contribute to the lower level of RIPK4 mRNA observed in SCC.

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PMC11129910

HMEC 5.6 RAB25- Clone#5 cells show 70% wound closure at the end of 24 hours, confirming the increased capacity of the cells to migrate.

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PMC11033180

F, F′) Higher magnification of the boxed regions in E, E′ illustrates the pericellular Plexin A1 labeling.(G and G′) Double immunolabeling for Plexin A2 (green) and Hu (red) in the myenteric plexus of rat distal colon.

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PMC11011837

The results shown in Figure 6 highlight the main lipid molecular species with differences in expression.

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PMC11762280

P < 0.001.

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PMC11777207

Unpaired Student’s t tests and one-way analysis of variance (ANOVA) were used.

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PMC11320084

Relative expression was calculated using the 2 method with glyceraldehyde 3‐phosphate dehydrogenase (GAPDH) as an internal control.

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PMC11657744

Cells were transfected with Cep89 or Fbf1-specific siRNAs and then treated with serum for 12 h to induce disassembly.

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PMC9429973

The use of G-CSF therapy has radically changed these patients’ outlook.

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PMC11519583

Furthermore, enhanced MP proliferation by glycerol injection into the TA muscles was markedly suppressed in Ror2 cKO mice compared with that in control mice (Fig. 3j–l).

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PMC11746942

These findings collectively demonstrate that targeting the S1PR3–Src–STAT3 axis through selective S1PR3 antagonism effectively alleviates psoriasis-like inflammation (Fig. 8).Fig.

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PMC11792888

In contrast, both NSCLC cell lines showed a significant accumulation of cells in the G2/M phase after incubation with 1.36 mg/mL of scorpion venom, from 13.62 ± 3.3% to 29.29 ± 4.54% for A549 and from 13.41 ± 4.22% to 25.81 ± 9.03% for NCIH460 cells (Figures 2 C and 2D).

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PMC4659567

The yields were 60–80%. [

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PMC11787355

Transfection was performed with Fugene HD transfection reagent (#E2312, Promega) following the manufacture instructions.

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PMC10482220

The association could be due to binding to G3BP partners or to direct G3BP self-association.

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PMC9844987

To simultaneously capture the spread of TSSs and their relative frequencies compared to total RNA expression within a promoter, we considered a width-normalized Shannon entropy as a measure of TSS positional dispersion (Hoskins et al., 2011).

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PMC10996034

Imiquimod facilitates chemoresistance via the upregulation of MMP1, and RNA interference targeting ZYX reduces tumor cell HN12 resistance to cisplatin (DDP) (21,22).

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PMC6461034

Repeat the above washing procedure with IP buffer once.

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PMC11283030

First, we performed CCK-8 assay to evaluate the effect of ACLY on proliferation of ccRCC cells.

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PMC11632064

Glycolytic reserve in human melanoma cell lines. (

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PMC7342409

Compared with the GIST882 imatinib-resistant group, the phosphorylation level in the imatinib group and the combination group was significantly lower (p<0.05), and the phosphorylation level in the CQ group was significantly higher (p<0.05).

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PMC9878278

Gene expression of IFNB1 was determined in Activin A exposed SC at 48 hpi using qRT-PCR. (

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PMC11228511

The expression of progerin in genetically modified mice triggers disease phenotypes similar to those in children with HGPS (e.g., skeletal abnormalities, osteoporosis, alopecia, vascular disease, sclerodermatous changes in the skin) (4–6).

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PMC11119602

The release of cytochrome C through BAX oligomeric pores formed in the mitochondrial membrane is the key event initiating the apoptotic cascade (Figure 8).

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PMC11594074

DNMT1 is a large protein with multiple domains, which primarily targets hemi-methylated DNA and is therefore strongly associated with methylation after replication as opposed to de novo methylation, which is catalyzed mainly by DNMT3A and 3B .

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PMC10440586

The data from the GLASS project were extracted from the synapse repositories (https://www.synapse.org/).

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PMC9275501

The mechanism was related to ROS, and the content of ROS was positively correlated with the inhibition of cell proliferation.

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PMC11394112

The MISTRG and MISTRG6 strains were not commercially available.

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PMC9429973

Methods: Retrospective evaluation of patients diagnosed with aPTT between 2009 and 2019 in a terciary center.

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PMC10674574

However, the documents proving the authenticity of the Caco-2 cell line are not strictly specified and are subject to the requirements of the relevant regulatory authority.

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PMC11300085

However, chemerin did not affect invasion of OVCAR-3 cells at different doses (Figure 2(d)).

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PMC9878562

Cell migration was calculated as described above.

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PMC9429973

Analysis of bone marrow (BM) biopsies of 15 consecutive APL patients at diagnosis, revealed a homogeneous staining for BCL2 in all cases.

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PMC11502443

However, tirzepatide makes an additional hydrogen bond with and arginine residue (R190) in the GIP receptor, which is hypothesized to facilitate changes in G protein binding affinity and signaling (Sun et al., 2022).

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