OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11594641	Firstly, FBS was filtered using a 0.22 μM pore filter membrane to dispose of larger vesicles before adding it to the culture medium.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC7642379	As suspension cell lines are cultivated under serum free conditions, the increased expression of genes associated with for instance cholesterol in suspension cell lines may be a result of a lower cholesterol content in the medium.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8996378	The results showed that its activity against MDR was lower than that of verapamil (FAR = 0.63 at 10 μM), which was inactive (Gao and Aisa, 2017).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11711127	For example, IL-10 produced during chronic infections promotes exhaustion, and simultaneous blockade of IL-10 and PD-1 improves reversion of exhaustion (68).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10667689	FITC mouse IgG1 κ isotype antibody (clone: MOPC-21; BioLegend, USA) was used to guarantee the specificity of the flow cytometric results.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10878518	A,B) The CAR expression on the surface of bone and soft-tissue sarcoma cells and fibroblasts was analyzed by flow cytometric analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11763126	Additionally, we found that CBDP1 exerts its antitumor effects by regulating the USP5/YTHDF2/TRPM3 axis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "we", "found", "that", "CBDP1", "exerts...
PMC5673060	Peptides were ionised by electrospray ionisation using 1.8 kV applied immediately pre-column via a microtee built into the nanospray source.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Peptides", "were", "ionised"...
PMC5308810	Immunoreactivity was detected using an ECL detection system (GE Healthcare Bio-Sciences Corp., Pittsburgh, PA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Immunoreactivity", "was", "detected", "using...
PMC11463018	In particularly, a higher degree of distinction between these triazolopyridines and approved SAHA against MDA-MB-231 cell line was observed, indicating their potential cellular potency against solid tumour cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11206502	When baseline and stressed OCR and ECAR values were independently compared, significantly higher values (p < 0.05; Kruskal–Wallis test) were found for the negative control, and lower HB concentrations (0.05 and 0.1 mg/mL) were found compared to the positive control and higher HB concentrations (0.2 and 0.4 mg/mL) (Figu...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11025866	Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) was used to measure viral lytic and cellular gene expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Reverse", "transcription-quantitative", "polymeras...
PMC9856122	Moreover, further cytotoxic assays were carried out using tumor cell lines to determine anti-HSV activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "further", "cytotoxic", "assays", "wer...
PMC9509578	Clonal and subclonal mutations are mainly responsible for the heterogeneity of tumors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Clonal", "and", "subclonal", "mutations", "are", "mainly", "responsible", "for", ...
PMC11471157	Sayuri Morito: Investigation.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Sayuri", "Morito", ":", "Investigation", "." ] } ]
PMC7351993	The DA node array is composed of six pairs of a 4-ch digitizer (AD9287-100EBZ, Analog Devices) and an FPGA board (SP601, Xilinx) with a 1-Gbps Ethernet port.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9352806	For lipidomics, worms (∼10000 worms each duplicate, 6 replicates per group) were transferred from NGM and washed five times with M9 buffer to collect worm pellets.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8193046	Each well of a flat-bottom clear 96 well plate was complemented with 20 µL of either of the compounds 16–25 (100 µM), 160 µL of ABCG2-overexpressing MDCK II BCRP cells (45,000 cells/well), as well as 20 µL of a pheophorbide A solution (5 µM), subsequently incubating the plate at 37 °C in a 5% CO2-humidified atmosphere ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6442998	Proportion of GIST samples exhibiting nuclear (48 cases) or diffuse (20 cases) YAP-ir.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Proportion", "of", "GIST", "samples", "exhibiting...
PMC10944868	MSAs and MDAs exhibit contrasting effects on MT polymer mass at high concentrations, inducing depolymerization or stabilization.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MSAs", "and", "MDAs", "exhibit", "cont...
PMC11740207	Investigating the differences between healthy and leukemic or cancerous VSELSCs, such as VSLSLCs and VSCSLCs, can reveal molecular and epigenetic mechanisms responsible for leukemia and cancer transformation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Methods: Forty-four patients were diagnosed with PRES out of 641 patients who underwent hematopoietic stem cell transplantation in Göztepe Medical Park Hospital Pediatric Bone Marrow Transplantation Unit, between April 2014 and November 2020, were evaluated retrospectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8336407	Treatment of the cells with different concentrations of extract revealed that the extract increases the antioxidant capacity in a dose-dependent manner in which treatment of the cells with 1.5, 2.0, and 2.5 mg/mL concentrations of extract increased this parameter to 1814 ± 64.85, 2498 ± 37.83, and 3952 ± 37.83 µM (p va...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11592837	Quantities of short and long fragments of nuclear (Alu) and mitochondrial (MTCO3) cfDNA were determined by quantitative real-time PCR (qPCR) on a Light-cycler 96 (Roche, Mannheim, Germany) using 2 µL of cell-free medium from the respective sample as a template.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11266100	The conventional electroporation solution, characterized by a sucrose-based composition (buffer No. 1), yields outcomes akin to buffers No. Two and seven when subjected to a voltage of 1.2 kV/cm or to nanosecond protocols.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10317042	Thus, vorinostat acts as an active agent in CCS cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", "vorinostat", "acts", "as", "an", "active", "agent", "in", "CCS", "...
PMC11640247	Notably, the defective phenotypes caused by the p.E62del, p.D63N, and p.Y64C variants, but not by p.Q61L, were rescued by DN-PAK1, reflecting the rescue observed in cortical neuron migration .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7189327	Interestingly, we found that the genes in submodule 1 were all upregulated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interestingly", ",", "we", "found", "that", "the", "genes", "in", "su...
PMC11715644	Through custom cell segmentation tools, we visualized individual cells within migrating monolayers by color-coding for their AR (Fig. 5B), SI (Fig. 5C), and combined AR and SI traits (Fig. 5D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9684669	Specifically, CAMK2D is highly up-regulated, and CAMK2B is down-regulated ( Figure 5A ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Specifically", ",", "CAMK2D", "is", "highly", "up-regulated", ...
PMC11568601	Furthermore, knocking down IRE1 with si-IRE1 or inhibiting of ER stress with 4-PBA suppressed the expression of ATF6, BiP, XBP1s and CHOP induced by TGT, as well as the expression of cleaved caspase-3 and cleaved PARP1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6889484	Supernatants were harvested every 2 to 3 days for up to 42 days and monitored by ELISA for p24 CA expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Supernatants", "were", ...
PMC11799620	The BHT was used as a standard.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "BHT", "was", "used", "as", "a", "standard", "." ] } ]
PMC11791203	In addition, the impact of petroleum ether extract on the HT29 cell line was evaluated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", "the", "impact", "of", ...
PMC9429973	However, individual approach must be applied in the selection of antineoplastic treatment and its timing, and in evaluating the risks of coronavirus infection reactivation during immunosuppressive therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10887351	The cardioprotective potential of β3-AR against HF was determined first from the KO-mice phenotype that lacks the receptor .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cardioprotective", "potential", "of",...
PMC9454852	Alternatively, DHR 123 fluorescence was registered by using confocal microscopy with the same setting described above for the measurement of free cytosolic Ca concentration.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11462673	Through H3K27ac CUT&Tag experiments, a significant reduction in H3K27ac enrichment was observed in this enhancer region after LDB1 knockdown (Fig. 6A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11394227	In this experiment, puromycin and tunicamycin were employed to induce cell apoptosis, and the apoptosis rate was quantified by flow cytometry.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC11766350	Results were obtained using a Biotek Synergy H1 plate reader at 450 and 650 nm wavelengths (Agilent, Santa Clara, CA, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11627060	To assess the dose-dependent effects, TQ, TQ-BSA NPs, and cisplatin were evaluated at concentrations ranging from 3.125 to 100 μg/mL. The effectiveness of the samples was assessed by incubating 96-well plates at 36°C with 5% CO2, followed by examination after 24 h .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11279598	A control non-malignant human mammary epithelial cell line (HMEC) was obtained from commercial sources (Invitrogen/ThermoFisher Scientific, Carlsbad, CA, USA) and maintained in vitro as per the supplier’s recommendation .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11791203	Examination of the chloroform extract from H. malabarica unveiled four compounds with negative logKp and lower logS values.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Examination", "of", "the", "chloroform", ...
PMC6442998	The human GIST48 cell line was kindly provided by Dr. Ronald DeMatteo, Perelman School of Medicine, Philadelphia, PA, USA.	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	Pts with <5% leukemic blasts after induction cycle 1 will proceed to the first cycle of consolidation; pts with ≥5% residual blasts will undergo a second induction cycle.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11474209	Among all, the most common and harmful type of cyanobacterial toxins is MCs, often found in freshwater, estuaries, and coastal environments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC7348793	The second is that the PCR product containing the correct number of repeats is by far the most predominant one, and that no discrete products with an increased number of repeats were observed, regardless of the DNA polymerase used for amplification.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11467964	We further generated scoring system consisting of clinical features and risk scores.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "further", "generated", "scoring", "system", "consisting", "of", "clinical", ...
PMC11532793	Experiments were re-quantified with Salmon and Gibbs sampling to generate 100 Gibbs resamples per library.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Experiments", "were", "re-quantified", "with", "Salmon", "and", ...
PMC9436459	0.5 μg/mL (5-FU)BGC-823n.a.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "0.5", "μg/mL", "(5-FU)BGC-823n.a", "." ] } ]
PMC5035325	The intensity of EGFR expression in 13 (44 %) of 30 animals is strong while the most animals 14 (47 %) shown a weak reactivity to NeuGcGM3 ganglioside.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4839679	Of particular novelty is the identification of cell adhesion as a major downstream process uniquely regulated by PBRM1 expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Of", "particular", "novelty", "is...
PMC11587606	The confocal images of DAPI-stained equatorial cross sections of MCF-10 A/RH acini with CRT0066854; scale bar 20 μm (n = 3). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC11085211	In line with these observations, Annexin-V/7-AAD staining confirmed that imatinib promoted a slight increase (23.4% vs. 15.6%; p < 0.05) in early apoptotic cells compared to the control at 48 h (Figure 6b,c).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	For the diagnosis of ITP, a bone marrow (BM) study may be useful to differentiate between ITP and other diseases, such as myelodysplastic syndromes (MDS).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11530949	After that, the sediment was continuously washed with ethanol and distilled water (50/50 V/V) and allowed to dry overnight at 120 °C in a vacuum oven (33).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11411004	One-way analysis of variance (ANOVA) was used for statistical analysis. ****	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One-way", "analysis", "of", "variance", "(", "ANOVA", ...
PMC9596868	Values represent mean ± SD of two independent experiments analysed by two tailed paired student's t test (p ≤ 0.01; **p ≤ 0.0001). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8097906	Cell viability measurement via MTS-assay after treatment with VSM extract (1, 10, 25, 50 and 100 μg/ml) of the primary non-tumorigenic control cells: a human mesenchymal stem cells (hMSCs) and b human fibroblasts (NHDF), as well as of the RMA cell line: c HA-OH1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Of the four eIF2a-kinases in the human genome we determined that HRI (EIF2AK1) was uniquely required for BTM-3566 eIF2a phosphorylation, activation of the ATF4-ISR and induction of apoptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11803918	Notably, this approach preserved the antitumor functions of γδ-T exosomes while achieving a high encapsulation efficiency of drug molecules.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notably", ",", "this", ...
PMC11143482	For body weighing, all mice were removed from the cage by cup handling and placed within a plastic container on an animal digital weighing scale (ACS-ZC41/ZE41 Camry, Hong Kong).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11190538	C-phycocyanin also protects the liver by preventing hepatic lipid peroxidation, functioning as an antioxidant .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "C-phycocyanin", "also", "protects", "the", "liver", "by", "...
PMC11678448	The pathogens responsible for caprine pasteurellosis are P. multocida and M. haemolytica, with P. multocida being the primary causative agent .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "pathogens", ...
PMC9429973	Regarding PFS, the only independent variables were response to induction-therapy CR vs PR (HR 0.084; CI 0.038-0.187; p<0.001) and RTX maintenance (HR 0.251; CI 0.110-0.577; p=0.001).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Patients who do not achieve a complete remission (CR) after cycle 8 can receive an additional 6 monthly doses of obinotuzumab during cycles 9 -14.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11551844	Afterwards, a mixture of ethyl acetate and methanol (polar solvent) in various rations was used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Afterwards", ",", "a", "mixture", "of"...
PMC9429973	Methods: An electronic database search of 1056 patients with confirmed diagnosis of CLL who presented at St Paul’s Hospital, Vancouver, Canada over 30 years and between 1991 and 2021 was performed with 520 having a complete data set.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5363531	The time required for the scrape to heal, in each cell line, was also recorded.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "time", "required", "for", "the", "sc...
PMC8584319	AZD8055 inhibits 4E-BP1 phosphorylation and induces ERK1/2 and p38 phosphorylation, which are independent of each other.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "AZD8055", "inhibits", "4E-BP1", "phosphorylation", ...
PMC9454852	The fluorescence change was assessed using a plate reader (ex 485 nm/em 535 nm).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "fluorescence", "change", "was", "assessed", "us...
PMC8864075	As above, we found that reTFAE inhibited the PI3K/Akt pathway and TWIST, yet how reTFAE led to the decline of EMT is not clear.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC8009078	Mean RoG of TMPRSS2 bound with proposed molecules (A1–A5) was seen to be less than 25 Å. The RMSD and RMSF profile of the TMPRSS2 inhibitors in our previous publication were also corroborated with the current findings.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6312945	All the samples were repeated in triplicate, and the results were analyzed by using the 2 method.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "the", "samples", "were", "repea...
PMC10747160	Although the Mono-Grft that we produced appeared to be well-folded on NMR, the sample was only able to be resuspended into pH 2.5 buffer, and it aggregated over the course of an hour at pH 6.5–7.0 (Figure S1A,B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7570809	AKT is an important effector of cell survival whose phosphorylation determines the activation of PI3K pathway triggered by integrin signaling .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "AKT", "is", "an",...
PMC7961460	Among these there are inhibitor of differentiation proteins , growth factors with paracrine signalling to re-program surrounding fibroblasts , chemokines and tumour-specific antigens that contributes to recruit and transform immune cells to sustain tumour survival .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11495567	Mutated KRAS is the most common driver gene in lung adenocarcinoma, the most common histological subtype of lung cancer, in White and Black Americans alike .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11765988	Hypothetically, the increased oxidative stress seen in sarcoidosis might affect, when out-of-proportion cell metabolism and predispose to carcinogenesis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hypothetically", ",", "the",...
PMC11209164	The 786-0 cells were plated to confluency in 12-well plates and incubated overnight at 37 °C in a 5% CO2 humidified incubator.	[ { "tags": [ "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC11696659	In this study investigating the use of highly accurate and sensitive techniques for the analysis of telomeres, we found that patients in the cancer cohort had a higher proportion of short telomeres compared to the control cohort, suggesting that technology could be considered a useful diagnostic tool during early scree...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11064533	The proteins differentially expressed between adhered and planktonic bacterial cells were identified using the label-free quantification algorithm provided by MaxQuant (LFQ) (39) and further analyzed with the limma R package.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11694066	Mean ± SD; n = 3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mean", "±", "SD", ";", "n", "=", "3", "." ] } ]
PMC9429973	Image: Summary/Conclusion: The combination of EZH2 inhibitor DZNeP and BCL2 inhibitor Venetoclax exhibited a strong synergistic cell proliferation arrest and apoptosis of AML cells in PIK3IP1 dependent manner.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10178190	Therefore, it is not surprising that HS-5-derived CM did not confer chemoresistance to all OC cell lines tested, while CM derived from the tumor-activated HS-5 promoted platinum RJY13 resistance in all of the OC cell lines tested.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Patients aged 18 years or above with morphologically documented RR-AML, ECOG performance status 0-2 and adequate organ function were eligible.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patient...
PMC11731614	The predicted protein targets for let-7 and miR-23 were obtained by cross-referencing 3 separate databases: MirDB, TargetScan, and DIANA-microT. The protein targets predicted by all three programs were used for downstream analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11449273	H1299- p53 and H1299-PG-p53 were run on the same gel separated by a lane.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "H1299-", "p53", "and", "H1299-PG-p53", "were", "run", "on", "the...
PMC11087055	Axes are shown.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "Axes", "are", "shown", "." ] } ]
PMC11733919	b–f) Senescence program was induced in normal and cancer cells by hydrogen peroxide (SIPS) and etoposide (TIS) stimulation, respectively. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	R were defined as patients with duration of response (DoR) ≥3 months after bone marrow (BM) complete remission (CR) achievement.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11360263	HCMV infection of OECs with these high-risk HCMV strains created a pro-oncogenic environment, leading to sustained growth of CMV-transformed OECs and the formation of colonies in soft agar.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11347429	Visualization and analyses of PLINK and GenomeStudio output files were performed using the R software package (50).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Visualization", "and", "analyses", ...
PMC10812665	However, the downstream response of the cells can be very complex, in that only subsets of the target genes are affected.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However...
PMC5839394	Briefly cells were fixed in 70% ethanol, washed in PBS and resuspended in DNA extraction buffer (200 mM Na2HPO4, 0.1% Triton X-100).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11243198	GANT61 was purchased from TOCRIS (Minneapolis, MN, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GANT61", "was", "purchased", "from", "TOCRIS", "(", "Minneapolis", ",", "MN", ...
PMC11674441	Because there was a marked increase in lymphocyte response to several HLA class II-restricted neoantigens, we speculate that strong antitumor immune effect may have occurred and induced antigen spreading in these two cases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10877303	MERS-CoV's genome consists of ORF1a and ORF1b, which produce two large polyproteins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MERS-CoV", "'s", "genome", "consists", "of", "ORF1a", "and", "OR...
PMC7053076	In the classical NF-κB pathway, various cellular receptors, such as tumor necrosis factor receptors (TNFRs), are activated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", ...
PMC11200978	These findings contribute to the ongoing efforts to improve treatment options for NSCLC, offering a promising approach that warrants further investigation in preclinical and clinical settings.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11594641

Firstly, FBS was filtered using a 0.22 μM pore filter membrane to dispose of larger vesicles before adding it to the culture medium.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC7642379

As suspension cell lines are cultivated under serum free conditions, the increased expression of genes associated with for instance cholesterol in suspension cell lines may be a result of a lower cholesterol content in the medium.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8996378

The results showed that its activity against MDR was lower than that of verapamil (FAR = 0.63 at 10 μM), which was inactive (Gao and Aisa, 2017).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11711127

For example, IL-10 produced during chronic infections promotes exhaustion, and simultaneous blockade of IL-10 and PD-1 improves reversion of exhaustion (68).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC10667689

FITC mouse IgG1 κ isotype antibody (clone: MOPC-21; BioLegend, USA) was used to guarantee the specificity of the flow cytometric results.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC10878518

A,B) The CAR expression on the surface of bone and soft-tissue sarcoma cells and fibroblasts was analyzed by flow cytometric analysis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11763126

Additionally, we found that CBDP1 exerts its antitumor effects by regulating the USP5/YTHDF2/TRPM3 axis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "we", "found", "that", "CBDP1", "exerts...

PMC5673060

Peptides were ionised by electrospray ionisation using 1.8 kV applied immediately pre-column via a microtee built into the nanospray source.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Peptides", "were", "ionised"...

PMC5308810

Immunoreactivity was detected using an ECL detection system (GE Healthcare Bio-Sciences Corp., Pittsburgh, PA).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Immunoreactivity", "was", "detected", "using...

PMC11463018

In particularly, a higher degree of distinction between these triazolopyridines and approved SAHA against MDA-MB-231 cell line was observed, indicating their potential cellular potency against solid tumour cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11206502

When baseline and stressed OCR and ECAR values were independently compared, significantly higher values (p < 0.05; Kruskal–Wallis test) were found for the negative control, and lower HB concentrations (0.05 and 0.1 mg/mL) were found compared to the positive control and higher HB concentrations (0.2 and 0.4 mg/mL) (Figu...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11025866

Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) was used to measure viral lytic and cellular gene expression.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Reverse", "transcription-quantitative", "polymeras...

PMC9856122

Moreover, further cytotoxic assays were carried out using tumor cell lines to determine anti-HSV activity.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "further", "cytotoxic", "assays", "wer...

PMC9509578

Clonal and subclonal mutations are mainly responsible for the heterogeneity of tumors.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Clonal", "and", "subclonal", "mutations", "are", "mainly", "responsible", "for", ...

PMC11471157

Sayuri Morito: Investigation.

[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Sayuri", "Morito", ":", "Investigation", "." ] } ]

PMC7351993

The DA node array is composed of six pairs of a 4-ch digitizer (AD9287-100EBZ, Analog Devices) and an FPGA board (SP601, Xilinx) with a 1-Gbps Ethernet port.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9352806

For lipidomics, worms (∼10000 worms each duplicate, 6 replicates per group) were transferred from NGM and washed five times with M9 buffer to collect worm pellets.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8193046

Each well of a flat-bottom clear 96 well plate was complemented with 20 µL of either of the compounds 16–25 (100 µM), 160 µL of ABCG2-overexpressing MDCK II BCRP cells (45,000 cells/well), as well as 20 µL of a pheophorbide A solution (5 µM), subsequently incubating the plate at 37 °C in a 5% CO2-humidified atmosphere ...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC6442998

Proportion of GIST samples exhibiting nuclear (48 cases) or diffuse (20 cases) YAP-ir.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Proportion", "of", "GIST", "samples", "exhibiting...

PMC10944868

MSAs and MDAs exhibit contrasting effects on MT polymer mass at high concentrations, inducing depolymerization or stabilization.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MSAs", "and", "MDAs", "exhibit", "cont...

PMC11740207

Investigating the differences between healthy and leukemic or cancerous VSELSCs, such as VSLSLCs and VSCSLCs, can reveal molecular and epigenetic mechanisms responsible for leukemia and cancer transformation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Methods: Forty-four patients were diagnosed with PRES out of 641 patients who underwent hematopoietic stem cell transplantation in Göztepe Medical Park Hospital Pediatric Bone Marrow Transplantation Unit, between April 2014 and November 2020, were evaluated retrospectively.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8336407

Treatment of the cells with different concentrations of extract revealed that the extract increases the antioxidant capacity in a dose-dependent manner in which treatment of the cells with 1.5, 2.0, and 2.5 mg/mL concentrations of extract increased this parameter to 1814 ± 64.85, 2498 ± 37.83, and 3952 ± 37.83 µM (p va...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11592837

Quantities of short and long fragments of nuclear (Alu) and mitochondrial (MTCO3) cfDNA were determined by quantitative real-time PCR (qPCR) on a Light-cycler 96 (Roche, Mannheim, Germany) using 2 µL of cell-free medium from the respective sample as a template.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11266100

The conventional electroporation solution, characterized by a sucrose-based composition (buffer No. 1), yields outcomes akin to buffers No. Two and seven when subjected to a voltage of 1.2 kV/cm or to nanosecond protocols.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10317042

Thus, vorinostat acts as an active agent in CCS cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", "vorinostat", "acts", "as", "an", "active", "agent", "in", "CCS", "...

PMC11640247

Notably, the defective phenotypes caused by the p.E62del, p.D63N, and p.Y64C variants, but not by p.Q61L, were rescued by DN-PAK1, reflecting the rescue observed in cortical neuron migration .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7189327

Interestingly, we found that the genes in submodule 1 were all upregulated.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interestingly", ",", "we", "found", "that", "the", "genes", "in", "su...

PMC11715644

Through custom cell segmentation tools, we visualized individual cells within migrating monolayers by color-coding for their AR (Fig. 5B), SI (Fig. 5C), and combined AR and SI traits (Fig. 5D).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9684669

Specifically, CAMK2D is highly up-regulated, and CAMK2B is down-regulated ( Figure 5A ).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Specifically", ",", "CAMK2D", "is", "highly", "up-regulated", ...

PMC11568601

Furthermore, knocking down IRE1 with si-IRE1 or inhibiting of ER stress with 4-PBA suppressed the expression of ATF6, BiP, XBP1s and CHOP induced by TGT, as well as the expression of cleaved caspase-3 and cleaved PARP1.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC6889484

Supernatants were harvested every 2 to 3 days for up to 42 days and monitored by ELISA for p24 CA expression.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Supernatants", "were", ...

PMC11799620

The BHT was used as a standard.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "BHT", "was", "used", "as", "a", "standard", "." ] } ]

PMC11791203

In addition, the impact of petroleum ether extract on the HT29 cell line was evaluated.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", "the", "impact", "of", ...

PMC9429973

However, individual approach must be applied in the selection of antineoplastic treatment and its timing, and in evaluating the risks of coronavirus infection reactivation during immunosuppressive therapy.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10887351

The cardioprotective potential of β3-AR against HF was determined first from the KO-mice phenotype that lacks the receptor .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cardioprotective", "potential", "of",...

PMC9454852

Alternatively, DHR 123 fluorescence was registered by using confocal microscopy with the same setting described above for the measurement of free cytosolic Ca concentration.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC11462673

Through H3K27ac CUT&Tag experiments, a significant reduction in H3K27ac enrichment was observed in this enhancer region after LDB1 knockdown (Fig. 6A).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11394227

In this experiment, puromycin and tunicamycin were employed to induce cell apoptosis, and the apoptosis rate was quantified by flow cytometry.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...

PMC11766350

Results were obtained using a Biotek Synergy H1 plate reader at 450 and 650 nm wavelengths (Agilent, Santa Clara, CA, USA).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC11627060

To assess the dose-dependent effects, TQ, TQ-BSA NPs, and cisplatin were evaluated at concentrations ranging from 3.125 to 100 μg/mL. The effectiveness of the samples was assessed by incubating 96-well plates at 36°C with 5% CO2, followed by examination after 24 h .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11279598

A control non-malignant human mammary epithelial cell line (HMEC) was obtained from commercial sources (Invitrogen/ThermoFisher Scientific, Carlsbad, CA, USA) and maintained in vitro as per the supplier’s recommendation .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11791203

Examination of the chloroform extract from H. malabarica unveiled four compounds with negative logKp and lower logS values.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Examination", "of", "the", "chloroform", ...

PMC6442998

The human GIST48 cell line was kindly provided by Dr. Ronald DeMatteo, Perelman School of Medicine, Philadelphia, PA, USA.

[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC9429973

Pts with <5% leukemic blasts after induction cycle 1 will proceed to the first cycle of consolidation; pts with ≥5% residual blasts will undergo a second induction cycle.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11474209

Among all, the most common and harmful type of cyanobacterial toxins is MCs, often found in freshwater, estuaries, and coastal environments.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC7348793

The second is that the PCR product containing the correct number of repeats is by far the most predominant one, and that no discrete products with an increased number of repeats were observed, regardless of the DNA polymerase used for amplification.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11467964

We further generated scoring system consisting of clinical features and risk scores.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "further", "generated", "scoring", "system", "consisting", "of", "clinical", ...

PMC11532793

Experiments were re-quantified with Salmon and Gibbs sampling to generate 100 Gibbs resamples per library.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Experiments", "were", "re-quantified", "with", "Salmon", "and", ...

PMC9436459

0.5 μg/mL (5-FU)BGC-823n.a.

[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "0.5", "μg/mL", "(5-FU)BGC-823n.a", "." ] } ]

PMC5035325

The intensity of EGFR expression in 13 (44 %) of 30 animals is strong while the most animals 14 (47 %) shown a weak reactivity to NeuGcGM3 ganglioside.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC4839679

Of particular novelty is the identification of cell adhesion as a major downstream process uniquely regulated by PBRM1 expression.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Of", "particular", "novelty", "is...

PMC11587606

The confocal images of DAPI-stained equatorial cross sections of MCF-10 A/RH acini with CRT0066854; scale bar 20 μm (n = 3). (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...

PMC11085211

In line with these observations, Annexin-V/7-AAD staining confirmed that imatinib promoted a slight increase (23.4% vs. 15.6%; p < 0.05) in early apoptotic cells compared to the control at 48 h (Figure 6b,c).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

For the diagnosis of ITP, a bone marrow (BM) study may be useful to differentiate between ITP and other diseases, such as myelodysplastic syndromes (MDS).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11530949

After that, the sediment was continuously washed with ethanol and distilled water (50/50 V/V) and allowed to dry overnight at 120 °C in a vacuum oven (33).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11411004

One-way analysis of variance (ANOVA) was used for statistical analysis. ****

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One-way", "analysis", "of", "variance", "(", "ANOVA", ...

PMC9596868

Values represent mean ± SD of two independent experiments analysed by two tailed paired student's t test (**p ≤ 0.01; ****p ≤ 0.0001). (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8097906

Cell viability measurement via MTS-assay after treatment with VSM extract (1, 10, 25, 50 and 100 μg/ml) of the primary non-tumorigenic control cells: a human mesenchymal stem cells (hMSCs) and b human fibroblasts (NHDF), as well as of the RMA cell line: c HA-OH1.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Of the four eIF2a-kinases in the human genome we determined that HRI (EIF2AK1) was uniquely required for BTM-3566 eIF2a phosphorylation, activation of the ATF4-ISR and induction of apoptosis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11803918

Notably, this approach preserved the antitumor functions of γδ-T exosomes while achieving a high encapsulation efficiency of drug molecules.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notably", ",", "this", ...

PMC11143482

For body weighing, all mice were removed from the cage by cup handling and placed within a plastic container on an animal digital weighing scale (ACS-ZC41/ZE41 Camry, Hong Kong).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11190538

C-phycocyanin also protects the liver by preventing hepatic lipid peroxidation, functioning as an antioxidant .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "C-phycocyanin", "also", "protects", "the", "liver", "by", "...

PMC11678448

The pathogens responsible for caprine pasteurellosis are P. multocida and M. haemolytica, with P. multocida being the primary causative agent .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "pathogens", ...

PMC9429973

Regarding PFS, the only independent variables were response to induction-therapy CR vs PR (HR 0.084; CI 0.038-0.187; p<0.001) and RTX maintenance (HR 0.251; CI 0.110-0.577; p=0.001).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Patients who do not achieve a complete remission (CR) after cycle 8 can receive an additional 6 monthly doses of obinotuzumab during cycles 9 -14.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11551844

Afterwards, a mixture of ethyl acetate and methanol (polar solvent) in various rations was used.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Afterwards", ",", "a", "mixture", "of"...

PMC9429973

Methods: An electronic database search of 1056 patients with confirmed diagnosis of CLL who presented at St Paul’s Hospital, Vancouver, Canada over 30 years and between 1991 and 2021 was performed with 520 having a complete data set.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC5363531

The time required for the scrape to heal, in each cell line, was also recorded.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "time", "required", "for", "the", "sc...

PMC8584319

AZD8055 inhibits 4E-BP1 phosphorylation and induces ERK1/2 and p38 phosphorylation, which are independent of each other.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "AZD8055", "inhibits", "4E-BP1", "phosphorylation", ...

PMC9454852

The fluorescence change was assessed using a plate reader (ex 485 nm/em 535 nm).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "fluorescence", "change", "was", "assessed", "us...

PMC8864075

As above, we found that reTFAE inhibited the PI3K/Akt pathway and TWIST, yet how reTFAE led to the decline of EMT is not clear.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC8009078

Mean RoG of TMPRSS2 bound with proposed molecules (A1–A5) was seen to be less than 25 Å. The RMSD and RMSF profile of the TMPRSS2 inhibitors in our previous publication were also corroborated with the current findings.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC6312945

All the samples were repeated in triplicate, and the results were analyzed by using the 2 method.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "the", "samples", "were", "repea...

PMC10747160

Although the Mono-Grft that we produced appeared to be well-folded on NMR, the sample was only able to be resuspended into pH 2.5 buffer, and it aggregated over the course of an hour at pH 6.5–7.0 (Figure S1A,B).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7570809

AKT is an important effector of cell survival whose phosphorylation determines the activation of PI3K pathway triggered by integrin signaling .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "AKT", "is", "an",...

PMC7961460

Among these there are inhibitor of differentiation proteins , growth factors with paracrine signalling to re-program surrounding fibroblasts , chemokines and tumour-specific antigens that contributes to recruit and transform immune cells to sustain tumour survival .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11495567

Mutated KRAS is the most common driver gene in lung adenocarcinoma, the most common histological subtype of lung cancer, in White and Black Americans alike .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11765988

Hypothetically, the increased oxidative stress seen in sarcoidosis might affect, when out-of-proportion cell metabolism and predispose to carcinogenesis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hypothetically", ",", "the",...

PMC11209164

The 786-0 cells were plated to confluency in 12-well plates and incubated overnight at 37 °C in a 5% CO2 humidified incubator.

[ { "tags": [ "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...

PMC11696659

In this study investigating the use of highly accurate and sensitive techniques for the analysis of telomeres, we found that patients in the cancer cohort had a higher proportion of short telomeres compared to the control cohort, suggesting that technology could be considered a useful diagnostic tool during early scree...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11064533

The proteins differentially expressed between adhered and planktonic bacterial cells were identified using the label-free quantification algorithm provided by MaxQuant (LFQ) (39) and further analyzed with the limma R package.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11694066

Mean ± SD; n = 3.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mean", "±", "SD", ";", "n", "=", "3", "." ] } ]

PMC9429973

Image: Summary/Conclusion: The combination of EZH2 inhibitor DZNeP and BCL2 inhibitor Venetoclax exhibited a strong synergistic cell proliferation arrest and apoptosis of AML cells in PIK3IP1 dependent manner.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10178190

Therefore, it is not surprising that HS-5-derived CM did not confer chemoresistance to all OC cell lines tested, while CM derived from the tumor-activated HS-5 promoted platinum RJY13 resistance in all of the OC cell lines tested.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Patients aged 18 years or above with morphologically documented RR-AML, ECOG performance status 0-2 and adequate organ function were eligible.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patient...

PMC11731614

The predicted protein targets for let-7 and miR-23 were obtained by cross-referencing 3 separate databases: MirDB, TargetScan, and DIANA-microT. The protein targets predicted by all three programs were used for downstream analysis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11449273

H1299- p53 and H1299-PG-p53 were run on the same gel separated by a lane.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "H1299-", "p53", "and", "H1299-PG-p53", "were", "run", "on", "the...

PMC11087055

Axes are shown.

[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "Axes", "are", "shown", "." ] } ]

PMC11733919

b–f) Senescence program was induced in normal and cancer cells by hydrogen peroxide (SIPS) and etoposide (TIS) stimulation, respectively. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

R were defined as patients with duration of response (DoR) ≥3 months after bone marrow (BM) complete remission (CR) achievement.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC11360263

HCMV infection of OECs with these high-risk HCMV strains created a pro-oncogenic environment, leading to sustained growth of CMV-transformed OECs and the formation of colonies in soft agar.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11347429

Visualization and analyses of PLINK and GenomeStudio output files were performed using the R software package (50).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Visualization", "and", "analyses", ...

PMC10812665

However, the downstream response of the cells can be very complex, in that only subsets of the target genes are affected.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However...

PMC5839394

Briefly cells were fixed in 70% ethanol, washed in PBS and resuspended in DNA extraction buffer (200 mM Na2HPO4, 0.1% Triton X-100).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11243198

GANT61 was purchased from TOCRIS (Minneapolis, MN, USA).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GANT61", "was", "purchased", "from", "TOCRIS", "(", "Minneapolis", ",", "MN", ...

PMC11674441

Because there was a marked increase in lymphocyte response to several HLA class II-restricted neoantigens, we speculate that strong antitumor immune effect may have occurred and induced antigen spreading in these two cases.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10877303

MERS-CoV's genome consists of ORF1a and ORF1b, which produce two large polyproteins.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MERS-CoV", "'s", "genome", "consists", "of", "ORF1a", "and", "OR...

PMC7053076

In the classical NF-κB pathway, various cellular receptors, such as tumor necrosis factor receptors (TNFRs), are activated.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", ...

PMC11200978

These findings contribute to the ongoing efforts to improve treatment options for NSCLC, offering a promising approach that warrants further investigation in preclinical and clinical settings.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...