OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC9429973	With a median follow up of 62 months (37-114), no significant association was observed between MYC-R partner and duration of response (p=0.784), event free survival (EFS) (p=0.933) or overall survival (OS) (p=0.706).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10812665	In some cell types (hepatocytes and astrocytes) a complete urea cycle takes an important role in this.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "some", "cell", "types", ...
PMC10048572	Of the 18 primary clones of Jurkat, 7 have a loss of a Y-chromosome marker (the amelogenin locus); 5 have LOH on D12S391 (3 of these clones also have loss of the amelogenin Y marker); 1 clone—LOH on FGA (4q); 1 on CSF1PO (5q33.1); and one on D8S1179 (8q).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11772585	Genes with a \|log2FC\|≥0.585 and a p-value and q-value cut-off ≤1 were classified as differentially expressed genes (DEGs).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Genes", "with", "a", "...
PMC11476222	For both methods, we compared the number of lipid identifications, percent recovery, and the intensity of extracted sphingolipids.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "both", "me...
PMC3019555	Bar, 10 µm.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Bar", ",", "10", "µm", "." ] } ]
PMC8557138	The major reason for the formation of the necrotic core is the wall thickness of the tissue-engineered grafts since wall thickness greater than 150 µm limits the diffusion of nutrients and gases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11730305	NPs at the temperatures up to 100 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "NPs", "at", "the", "temperatures", "up", "to", "100", "°", "C", "." ] } ]
PMC11700523	The detailed molecular mechanisms for MR proteins remain to be elucidated in future studies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "detailed", "molecular", "mechanisms", "for", "MR", "proteins", ...
PMC6627640	In solid tumors, PRC2 has mainly been associated with oncogenesis and a poor outcome, as a large number of epithelial malignancies have gain-of-function mutations or overexpression of polycomb components which has spurred the clinical development of EZH2 inhibitors .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10899471	However, these findings have still not clarified the cause of BATF2 downregulation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "these", "findings", "have", "still", "not", "clarified", ...
PMC9429973	Fifty-five percent were males.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Fifty-five", "percent", "were", "males", "." ] } ]
PMC11806106	For the dose-response curve, the mean of the respective agonist phase was normalized to the saturation phase.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "the", "dose-response", "curve", ...
PMC9398137	Co-treatment with venetoclax can overcome BCL2-mediated resistance to S63845, and enhance efficacy of MCL1 inhibitors in BCL2-positive aggressive B-NHL.The ability to attenuate cell death signaling pathways such as mitochondrial apoptosis is a hallmark of many cancers, including B-cell non–Hodgkin lymphomas (B-NHL).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Anemia was reported in 42% (≥Grade 3: 35%) and 27% (≥Grade 3: 19%) pts in Arm 3 and 2, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4685407	To investigate the efficiency of CRISPR-Cas9 gene targeting in CHO cells, the frequency of gene integration into chromosome O was analyzed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", ...
PMC9429973	Aims: To assess efficacy in subgroups of pts treated with SOC therapies in the LocoMMotion study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "To", "assess", "efficacy", "in...
PMC11599565	A1: Cluster analysis of the interaction networks of differentially expressed genes using STRING (http://www.string-db.org) with default parameters, including a minimum interaction score of 0.4 (medium confidence) and various interaction sources including Text mining, Experiments, Databases, Co-expression, Neighborhood,...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11628309	Although RA is used in most differentiation treatments, the concentrations vary from 1 to 20 μM. Additionally, the duration of differentiation is notably diverse, ranging from 1 to 12 days, along with the use of various culture media.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9473868	Thus, inhibition of the PI3K/Akt signaling pathway mediated an antiapoptotic action, which is the main therapeutic target for RA treatment .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", ...
PMC11747467	We also excluded genes expressed in less than three cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "also", "excluded", "genes", "expressed", "in", "less", "than", "three", "cells", "."...
PMC9429973	It is important to note that those patients reporting symptoms of higher intensity, frequency or impact in their QoL AEs had more visits than those reporting AEs of lower grade (p<0.05).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10055960	FTIR (υ, cm) = 3421 (m, N-H), 1592 (s, C=Npyridyl), 1583 (s, C=Nformamidinate).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10968586	Other studies using a very large concentration of OLE (600 μg/mL, ≈1100 μM) shed some light on a different mechanism ruling OLE-dependent induction of apoptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9268620	The apoptotic cells and apoptotic bodies could be clearly seen in the cells treated with higher concentrations of 10 and 30 μg/mL of damnacanthal.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11467964	Finally, the gene expression was quantified by Hieff qPCR SYBR Green Master Mix (High Rox Plus) (YEASEN Biotech Co., Ltd., 11203ES) and calculated with the 2−∆∆Ct method.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11694625	AO/EB staining was performed under a Leica DMIL LED inverted fluorescence microscope (Germany).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "AO/EB", "staining", "was", "performed", "under", "a", "Leic...
PMC9027909	Blastocystis sp., is a prevalent protist, which its pathogenicity is still unclear.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Blastocystis", "sp.", ",", "is", "a", "prevalent", "protist", ",...
PMC10094712	Background fluorescence was subtracted frame by frame using ImageJ’s Math Subtract plugin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Background", "fluorescence", "was", "subtracted", "frame", "by", "frame", "...
PMC11286266	All statistical analysis was performed by a two-sided unpaired Welch’s t-test and significance is indicated by asterisks (p < 0.05; p < 0.01; **p < 0.001; ns: non-significant). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10523483	Antibody information was provided in SI Appendix, Table S4.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Antibody", "information", "was", "provided", "in", "SI", "Appendix", ",", "Table", "S4", "...
PMC11489275	Patients who died within 1 month after the first hospitalization were defined as a “1-month non-survivor” group and patients who did not die within 1 month were defined as a “1-month survivor” group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11531744	KEGG is an analysis method for uncovering the specific biological pathways of certain enriched genes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "KEGG", "is", "an", "analysis", "method", "for", "uncovering...
PMC11395280	When crossed with MX-1 Cre mice, injection of the synthetic double-stranded RNA polyI:C leads to the expression of Cre recombinase in cells that have receptors for type I interferons .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11794847	T cells exhibit metabolic plasticity, allowing them to adjust their nutritional requirements based on the tissue environment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "T", "cells", "exhibit", "metabolic", "...
PMC11597291	The cell death distribution was determined via flow cytometry analysis (for PI fluorescence with λexc.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cell", "death", "distribution", "was", "determi...
PMC11286266	The expected molecular weight of GFP-ATF6α_TM--LD before cleavage is 67 and 45 kDa post-FURIN cleavage.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "expected", "molecular", "weight", "of", ...
PMC11599565	Naturally occurring cells with distinctive morphology in SKOV3 cells (A-C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O" ], "tokens": [ "Naturally", "occurring", "cells", "with", "distinctive", "morphology", "in", ...
PMC9429973	Data on clinical workup and therapeutic strategies adopted are largely lacking due to the rarity of the disease and the limited number of dedicated clinical trials.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11482552	Subsequently, the following cell suspensions of 1000, 10,000 and 100,000 cells were prepared in triplicate in 500 µL (total number = 9 Eppendorf tubes) of complete medium.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11718109	Scale bar, 10 μm; inset: 2.5 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", ",", "10", "μm", ";", "inset", ":", "2.5", "μm", "." ] } ]
PMC9429973	Among 9936 pts, 55 pts (0.5%) had t(6;9) (48 AML, 7 HR-MDS).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Among", "9936", "pts", ...
PMC7841189	In China, the incidence of thyroid carcinoma has been experiencing a significant rise in recent years1,2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "China", ",", "the", "incidence", "of"...
PMC7887261	Last, we have focused on the investigation of predicted LoF variants which provide directionality of effect.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Last", ",", "we", "have", "focused", "on", ...
PMC11361748	The tissues were rinsed in 10 ml of skin digestion medium (450 ml HBSS, 50 mlFBS, 1.1915 g HEPES, 0.9356 g EDTA, filtered through a 0.22 μm PVDF filter) for 30 min at 37°C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10747139	Kavukcu et al. (2023) described two Ru(II)–p-cymene complexes (46 with an aliphatic chain group and 47 with N,S,S triple coordination), which were investigated regarding their antitumoral activity effects against HepG2 cell lines using an MTT assay and focusing on cell death mechanisms.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7724160	Free induction decays (FID's) underwent Fourier transformation, automatic phase, and baseline correction prior to calibrating to DSS at 0 ppm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10243817	Collectively, our results suggest that disturbance of MEX3B/TGF-βR3 in epithelial cells may lead to reduced collagen production and subsequent edema formation in CRSwNP, particularly the eosinophilic type.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10958426	Scatter plots showed the correlation between expression level and CNV level in CNV regions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scatter", "plots", "showed", "the", "correlation", "between", "express...
PMC8164677	Affinity of best conformational pose of ligand-protein complex was measured by E-value (Kcal/mol).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Affinity", "of", "best", "conformational", "pose", "of", "l...
PMC8427838	Image magnification, 50 µM. White arrows point to filopodia-like protrusions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Image", "magnification", ",", "50", "µM.", "White", "arrows", "point", "to", "filopod...
PMC3019555	No effect on the protein levels or polysome association of GAPDH (Fig. 2) or p53 (not depicted) was observed after MTD treatment in any cell line.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11694625	Then they were trypsinized and no fewer than 10 cells were collected.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", "they", "were", "trypsinized", "and", "no", "fewer", "than", "10", ...
PMC11394730	The anticancer property of PTL was first validated in 1973 .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "anticancer", "property", "of", "PTL", "was", "first", "validated", "in", "1973", "....
PMC11777207	FITC paint consisted of FITC (5 mg/ml, Sigma-Aldrich) emulsified in a 1:1 ratio solution of dibutyl phthalate (Sigma-Aldrich) and acetone.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11769516	i.e., ochratoxin A (OTA) and patulin, found in feed, are regulated in many countries.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "i.e.", ",", "ochratoxin", "A", ...
PMC9429973	Methods: Patients with ECOG performance status 0-1 and R/R LBCL ≤12 months after first-line chemoimmunotherapy were randomized 1:1 to axi-cel or SOC (2-3 cycles of platinum-based chemoimmunotherapy; patients with partial or complete response [CR] proceeded to high-dose therapy with autologous stem cell transplantation)...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11190538	Spirulina is regarded as a high-quality food and nutraceutical supplement because of its high protein, fat, vitamins, minerals, chlorophyll, beta-carotene, and polysaccharides.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11591052	In parallel, another mouse mesodermal non-transformed cell line, NIH/3T3 fibroblasts, was used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O" ], "tokens": [ "In", "parallel", ",", "another", "mouse", "mesodermal", ...
PMC11401358	All flow cytometry experiments were performed by the Flow Cytometer (Attune NxT, Thermo Fisher, Singapore) and analysed by using FlowJo software (version 10.0.6).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Hyperferritinemia was associated with more profound fibrosis (p=0.007), cytopenias (p<0.05), % peripheral blasts (p<0.05), RBC and PLT transfusion dependence (p<0.05).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11787355	First probe was then detected with FastRed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "First", "probe", "was", "then", "detected", "with", "FastRed", "." ] } ]
PMC11087301	Melanoma cells forming vessel-like structures display pluripotent embryonic genotype.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Melanoma", "cells", "forming", "vessel-like", "structures", "display", "pluripotent", "embryonic", "genotype", ...
PMC10938377	In addition, there is evidence of non-covalently associated AuDPPBX in the form of residual (apparently depot) binding.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", ...
PMC9429973	Count normalization, differential gene expression and splice event analysis were performed with DESeq2, Limma and SGSseq, respectively; gene enrichment analysis was performed with Enrichr (p<0.05).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11357960	Statistical analyses were performed using Prism 10.0 (GraphPad Prism, RRID: SCR_002798) and SPSS 27.0 statistical software package (SPSS, RRID: SCR_002865).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9479186	The results showed that Complex I activity is inhibited and increased ROS burden in BEL-7404 and SK-HEP-1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O" ], "tokens": [ "The", "results", "showed", "that", ...
PMC10094992	As expected, treatment with NR6 significantly reduced the level of NADH, a product of ALDH1A3 activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "expected", ",", "treatment", "wi...
PMC11755519	WNT5A functions as an important glycoprotein ligand that activates the Wnt/β-catenin signaling pathway.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "WNT5A", "functions", "as", "an", "important", "glycoprotein", "ligand", "th...
PMC11665584	Furthermore, IPA of differentially expressed genes obtained from bulk RNA-Seq of whole mouse control and PITX1 skin highlights widespread pro-myeloid/granulocyte activation and recruitment pathways (Supplemental Figure 8A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11591030	Moreover, the protective effect of AOP was comparable to that of VA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "the", "protective", "effect", "of", "AOP", "was", "c...
PMC11594641	During the medium collection, the cells were additionally counted to validate the proportionate cell growth, and their viability was confirmed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "During", "th...
PMC10968586	These results seem to depend on the modulation of the tumor microenvironment, since HT was able to reduce the accumulation of myeloid-derived suppressor cells in lymphoid organs, bone marrow, and tumor tissues .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11696576	Red and blue dots indicate genes that are expressed differentially with an adjusted P-value < 0.01, while grey dots represent genes that are not.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10530622	OSA is often associated with resistant HTN , loss of dipper profile of blood pressure , and increased risk of severe cardiometabolic dysfunction .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "OSA", ...
PMC7723249	As previously described, using MDCK-1 polarized cells , we show here that CCHFV infects the Caco-2 polarized cells mainly on the basolateral side (Fig 1B) indicating a difference between HAZV and CCHFV entry strategy.	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC8592717	The use of PCA in combination with TCDD minimized the latter's toxicity through suppression of histopathological changes and TBARS levels and increasing SOD, CAT, GPx antioxidant enzymes activity; GSH levels; and sperm concentration and motility .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11680391	These questions were descriptive and were therefore not included in any further analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "questions", "were", "descriptive", "and", "were", "therefore", "no...
PMC11371627	No other specific structural or immunohistochemical abnormalities were detected (Figure 1D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "other", "specific", "structural", "or", "immunohistochemical", "abnormaliti...
PMC11519583	Although Ror1 and Ror2 are maintained at relatively low levels in adult tissues, accumulating evidence demonstrates that Ror1 and Ror2 expression increases in injured tissues to promote regeneration [7–9].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Of these patients, 48% received more than two lines of therapies after CAR-T. Response rates of select first therapies received after CAR-T are detailed in Table 1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11665555	Master regulator analysis revealed 3 key TFs, TBX2, SOX15, and OVOL1, in support of gemcitabine resistance (Figure 5A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11509224	arenaria collected in Okinawa .	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "arenaria", "collected", "in", "Okinawa", "." ] } ]
PMC11271800	The matrix protein secreted protein acidic and rich in cysteine 1 (SPARCL1) is typically downregulated in most cancers, and its expression in GIST is no exception.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Summary/Conclusion: PRLR expression is higher in AML patient samples, and correlates with chemoresistance and refractoriness, making the receptor an adequate biomarker for AML diagnosis and follow-up.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5716223	NGF did not affect significantly neither myoblast growth nor viability under standard culture condition (data not shown).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "NGF", "did", "not", "affect", ...
PMC11190538	This test is based on MTT cleavage by mitochondrial dehydrogenases from viable cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "test", "is", "based", "on", "MTT", "cleavage", "by", "mitocho...
PMC10253973	The Ru(II) complex with polypyridine ligand 55 (Figure 20) may reduce the toxic effects of β-amyloid because it has the ability to trap Cu(II) ions, which cause the formation of β-amyloid aggregates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11777207	We found no defect in DC migration in the presence of αPD-1 pembrolizumab, suggesting that the interaction between PD-1 and PD-L1 in cis (35) did not regulate DC migration (Fig. 1B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10919056	This difference may be due to the loss of channel function, which leads to a decrease in tumor inhibition ability (usually called tumor dormancy) (28, 29), and this inhibition ability depends on the function of gap junction coupling among cells (30).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11087766	The fact that these latter proteins only localize to their cognate nucleus demonstrates that these phages can discriminate between closely related homologs with significant sequence identity, suggesting the existence of phage-specific import recognition signals.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11760643	For all analyses, differences were considered significant if p < 0.05.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "all", "analyses", ",", "differences", "were", "considered", "significant", ...
PMC6835428	Notably, a recent meta-analysis showed that IP administration significantly improved progression-free survival in advanced HGSOC patients compared to systemic administration .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notably", ",", "a...
PMC9096373	The possible mechanisms of APA combined with RT.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "possible", "mechanisms", "of", "APA", "combined", "with", "RT", "." ] } ]
PMC11754784	The study was approved by the Ethics Committee at Renji Hospital, School of Medicine, Shanghai Jiao Tong University (protocol number: KY2024-070-C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3203927	The above genes may play other roles besides being factors involved with hypoxia induced angiogenesis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "above", "genes", "may", "play", "other", "roles", ...
PMC9065483	By the same token, inhibition of EGFR by genetic or pharmacological means has also been reported to activate the interferon pathway in several contexts.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	Methods: Retrospective analysis of requests for plasma transfusion in adults, in our institution, between January/2020 and January/2022, This audit was undertaken to determine current use of FFP and to see if any improvements in the use of this component in relation to recommended guidance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11705547	Recent evidence have shown that cisplatin can inhibit cancer progression by activating anti-tumor immune responses .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Recent", "evidence", "have", "shown", "that", "cisplatin", ...
PMC11344246	RO-3306, Apcin, and DCZ0415 were purchased from MedChemExpress.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RO-3306", ",", "Apcin", ",", "and", "DCZ0415", "were", "purchased", "from", "MedChemExpress", ...

PMC9429973

With a median follow up of 62 months (37-114), no significant association was observed between MYC-R partner and duration of response (p=0.784), event free survival (EFS) (p=0.933) or overall survival (OS) (p=0.706).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10812665

In some cell types (hepatocytes and astrocytes) a complete urea cycle takes an important role in this.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "some", "cell", "types", ...

PMC10048572

Of the 18 primary clones of Jurkat, 7 have a loss of a Y-chromosome marker (the amelogenin locus); 5 have LOH on D12S391 (3 of these clones also have loss of the amelogenin Y marker); 1 clone—LOH on FGA (4q); 1 on CSF1PO (5q33.1); and one on D8S1179 (8q).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11772585

Genes with a |log2FC|≥0.585 and a p-value and q-value cut-off ≤1 were classified as differentially expressed genes (DEGs).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Genes", "with", "a", "...

PMC11476222

For both methods, we compared the number of lipid identifications, percent recovery, and the intensity of extracted sphingolipids.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "both", "me...

PMC3019555

Bar, 10 µm.

[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Bar", ",", "10", "µm", "." ] } ]

PMC8557138

The major reason for the formation of the necrotic core is the wall thickness of the tissue-engineered grafts since wall thickness greater than 150 µm limits the diffusion of nutrients and gases.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11730305

NPs at the temperatures up to 100 °C.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "NPs", "at", "the", "temperatures", "up", "to", "100", "°", "C", "." ] } ]

PMC11700523

The detailed molecular mechanisms for MR proteins remain to be elucidated in future studies.

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PMC6627640

In solid tumors, PRC2 has mainly been associated with oncogenesis and a poor outcome, as a large number of epithelial malignancies have gain-of-function mutations or overexpression of polycomb components which has spurred the clinical development of EZH2 inhibitors .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10899471

However, these findings have still not clarified the cause of BATF2 downregulation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "these", "findings", "have", "still", "not", "clarified", ...

PMC9429973

Fifty-five percent were males.

[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Fifty-five", "percent", "were", "males", "." ] } ]

PMC11806106

For the dose-response curve, the mean of the respective agonist phase was normalized to the saturation phase.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "the", "dose-response", "curve", ...

PMC9398137

Co-treatment with venetoclax can overcome BCL2-mediated resistance to S63845, and enhance efficacy of MCL1 inhibitors in BCL2-positive aggressive B-NHL.The ability to attenuate cell death signaling pathways such as mitochondrial apoptosis is a hallmark of many cancers, including B-cell non–Hodgkin lymphomas (B-NHL).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Anemia was reported in 42% (≥Grade 3: 35%) and 27% (≥Grade 3: 19%) pts in Arm 3 and 2, respectively.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC4685407

To investigate the efficiency of CRISPR-Cas9 gene targeting in CHO cells, the frequency of gene integration into chromosome O was analyzed.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", ...

PMC9429973

Aims: To assess efficacy in subgroups of pts treated with SOC therapies in the LocoMMotion study.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "To", "assess", "efficacy", "in...

PMC11599565

A1: Cluster analysis of the interaction networks of differentially expressed genes using STRING (http://www.string-db.org) with default parameters, including a minimum interaction score of 0.4 (medium confidence) and various interaction sources including Text mining, Experiments, Databases, Co-expression, Neighborhood,...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11628309

Although RA is used in most differentiation treatments, the concentrations vary from 1 to 20 μM. Additionally, the duration of differentiation is notably diverse, ranging from 1 to 12 days, along with the use of various culture media.

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PMC9473868

Thus, inhibition of the PI3K/Akt signaling pathway mediated an antiapoptotic action, which is the main therapeutic target for RA treatment .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", ...

PMC11747467

We also excluded genes expressed in less than three cells.

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PMC9429973

It is important to note that those patients reporting symptoms of higher intensity, frequency or impact in their QoL AEs had more visits than those reporting AEs of lower grade (p<0.05).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10055960

FTIR (υ, cm) = 3421 (m, N-H), 1592 (s, C=Npyridyl), 1583 (s, C=Nformamidinate).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10968586

Other studies using a very large concentration of OLE (600 μg/mL, ≈1100 μM) shed some light on a different mechanism ruling OLE-dependent induction of apoptosis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9268620

The apoptotic cells and apoptotic bodies could be clearly seen in the cells treated with higher concentrations of 10 and 30 μg/mL of damnacanthal.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11467964

Finally, the gene expression was quantified by Hieff qPCR SYBR Green Master Mix (High Rox Plus) (YEASEN Biotech Co., Ltd., 11203ES) and calculated with the 2−∆∆Ct method.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11694625

AO/EB staining was performed under a Leica DMIL LED inverted fluorescence microscope (Germany).

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PMC9027909

Blastocystis sp., is a prevalent protist, which its pathogenicity is still unclear.

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PMC10094712

Background fluorescence was subtracted frame by frame using ImageJ’s Math Subtract plugin.

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PMC11286266

All statistical analysis was performed by a two-sided unpaired Welch’s t-test and significance is indicated by asterisks (*p < 0.05; **p < 0.01; ***p < 0.001; ns: non-significant). (

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PMC10523483

Antibody information was provided in SI Appendix, Table S4.

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PMC11489275

Patients who died within 1 month after the first hospitalization were defined as a “1-month non-survivor” group and patients who did not die within 1 month were defined as a “1-month survivor” group.

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PMC11531744

KEGG is an analysis method for uncovering the specific biological pathways of certain enriched genes.

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PMC11395280

When crossed with MX-1 Cre mice, injection of the synthetic double-stranded RNA polyI:C leads to the expression of Cre recombinase in cells that have receptors for type I interferons .

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PMC11794847

T cells exhibit metabolic plasticity, allowing them to adjust their nutritional requirements based on the tissue environment.

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PMC11597291

The cell death distribution was determined via flow cytometry analysis (for PI fluorescence with λexc.

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PMC11286266

The expected molecular weight of GFP-ATF6α_TM--LD before cleavage is 67 and 45 kDa post-FURIN cleavage.

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PMC11599565

Naturally occurring cells with distinctive morphology in SKOV3 cells (A-C).

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PMC9429973

Data on clinical workup and therapeutic strategies adopted are largely lacking due to the rarity of the disease and the limited number of dedicated clinical trials.

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PMC11482552

Subsequently, the following cell suspensions of 1000, 10,000 and 100,000 cells were prepared in triplicate in 500 µL (total number = 9 Eppendorf tubes) of complete medium.

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PMC11718109

Scale bar, 10 μm; inset: 2.5 μm.

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PMC9429973

Among 9936 pts, 55 pts (0.5%) had t(6;9) (48 AML, 7 HR-MDS).

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PMC7841189

In China, the incidence of thyroid carcinoma has been experiencing a significant rise in recent years1,2.

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PMC7887261

Last, we have focused on the investigation of predicted LoF variants which provide directionality of effect.

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PMC11361748

The tissues were rinsed in 10 ml of skin digestion medium (450 ml HBSS, 50 mlFBS, 1.1915 g HEPES, 0.9356 g EDTA, filtered through a 0.22 μm PVDF filter) for 30 min at 37°C.

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PMC10747139

Kavukcu et al. (2023) described two Ru(II)–p-cymene complexes (46 with an aliphatic chain group and 47 with N,S,S triple coordination), which were investigated regarding their antitumoral activity effects against HepG2 cell lines using an MTT assay and focusing on cell death mechanisms.

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PMC7724160

Free induction decays (FID's) underwent Fourier transformation, automatic phase, and baseline correction prior to calibrating to DSS at 0 ppm.

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PMC10243817

Collectively, our results suggest that disturbance of MEX3B/TGF-βR3 in epithelial cells may lead to reduced collagen production and subsequent edema formation in CRSwNP, particularly the eosinophilic type.

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PMC10958426

Scatter plots showed the correlation between expression level and CNV level in CNV regions.

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PMC8164677

Affinity of best conformational pose of ligand-protein complex was measured by E-value (Kcal/mol).

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PMC8427838

Image magnification, 50 µM. White arrows point to filopodia-like protrusions.

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PMC3019555

No effect on the protein levels or polysome association of GAPDH (Fig. 2) or p53 (not depicted) was observed after MTD treatment in any cell line.

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PMC11694625

Then they were trypsinized and no fewer than 10 cells were collected.

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PMC11394730

The anticancer property of PTL was first validated in 1973 .

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PMC11777207

FITC paint consisted of FITC (5 mg/ml, Sigma-Aldrich) emulsified in a 1:1 ratio solution of dibutyl phthalate (Sigma-Aldrich) and acetone.

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PMC11769516

i.e., ochratoxin A (OTA) and patulin, found in feed, are regulated in many countries.

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PMC9429973

Methods: Patients with ECOG performance status 0-1 and R/R LBCL ≤12 months after first-line chemoimmunotherapy were randomized 1:1 to axi-cel or SOC (2-3 cycles of platinum-based chemoimmunotherapy; patients with partial or complete response [CR] proceeded to high-dose therapy with autologous stem cell transplantation)...

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PMC11190538

Spirulina is regarded as a high-quality food and nutraceutical supplement because of its high protein, fat, vitamins, minerals, chlorophyll, beta-carotene, and polysaccharides.

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PMC11591052

In parallel, another mouse mesodermal non-transformed cell line, NIH/3T3 fibroblasts, was used.

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PMC11401358

All flow cytometry experiments were performed by the Flow Cytometer (Attune NxT, Thermo Fisher, Singapore) and analysed by using FlowJo software (version 10.0.6).

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PMC9429973

Hyperferritinemia was associated with more profound fibrosis (p=0.007), cytopenias (p<0.05), % peripheral blasts (p<0.05), RBC and PLT transfusion dependence (p<0.05).

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PMC11787355

First probe was then detected with FastRed.

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PMC11087301

Melanoma cells forming vessel-like structures display pluripotent embryonic genotype.

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PMC10938377

In addition, there is evidence of non-covalently associated AuDPPBX in the form of residual (apparently depot) binding.

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PMC9429973

Count normalization, differential gene expression and splice event analysis were performed with DESeq2, Limma and SGSseq, respectively; gene enrichment analysis was performed with Enrichr (p<0.05).

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PMC11357960

Statistical analyses were performed using Prism 10.0 (GraphPad Prism, RRID: SCR_002798) and SPSS 27.0 statistical software package (SPSS, RRID: SCR_002865).

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PMC9479186

The results showed that Complex I activity is inhibited and increased ROS burden in BEL-7404 and SK-HEP-1.

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PMC10094992

As expected, treatment with NR6 significantly reduced the level of NADH, a product of ALDH1A3 activity.

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PMC11755519

WNT5A functions as an important glycoprotein ligand that activates the Wnt/β-catenin signaling pathway.

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PMC11665584

Furthermore, IPA of differentially expressed genes obtained from bulk RNA-Seq of whole mouse control and PITX1 skin highlights widespread pro-myeloid/granulocyte activation and recruitment pathways (Supplemental Figure 8A).

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PMC11591030

Moreover, the protective effect of AOP was comparable to that of VA.

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PMC11594641

During the medium collection, the cells were additionally counted to validate the proportionate cell growth, and their viability was confirmed.

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PMC10968586

These results seem to depend on the modulation of the tumor microenvironment, since HT was able to reduce the accumulation of myeloid-derived suppressor cells in lymphoid organs, bone marrow, and tumor tissues .

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PMC11696576

Red and blue dots indicate genes that are expressed differentially with an adjusted P-value < 0.01, while grey dots represent genes that are not.

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PMC10530622

OSA is often associated with resistant HTN , loss of dipper profile of blood pressure , and increased risk of severe cardiometabolic dysfunction .

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PMC7723249

As previously described, using MDCK-1 polarized cells , we show here that CCHFV infects the Caco-2 polarized cells mainly on the basolateral side (Fig 1B) indicating a difference between HAZV and CCHFV entry strategy.

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PMC8592717

The use of PCA in combination with TCDD minimized the latter's toxicity through suppression of histopathological changes and TBARS levels and increasing SOD, CAT, GPx antioxidant enzymes activity; GSH levels; and sperm concentration and motility .

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PMC11680391

These questions were descriptive and were therefore not included in any further analysis.

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PMC11371627

No other specific structural or immunohistochemical abnormalities were detected (Figure 1D).

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PMC11519583

Although Ror1 and Ror2 are maintained at relatively low levels in adult tissues, accumulating evidence demonstrates that Ror1 and Ror2 expression increases in injured tissues to promote regeneration [7–9].

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PMC9429973

Of these patients, 48% received more than two lines of therapies after CAR-T. Response rates of select first therapies received after CAR-T are detailed in Table 1.

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PMC11665555

Master regulator analysis revealed 3 key TFs, TBX2, SOX15, and OVOL1, in support of gemcitabine resistance (Figure 5A).

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PMC11509224

arenaria collected in Okinawa .

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PMC11271800

The matrix protein secreted protein acidic and rich in cysteine 1 (SPARCL1) is typically downregulated in most cancers, and its expression in GIST is no exception.

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PMC9429973

Summary/Conclusion: PRLR expression is higher in AML patient samples, and correlates with chemoresistance and refractoriness, making the receptor an adequate biomarker for AML diagnosis and follow-up.

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PMC5716223

NGF did not affect significantly neither myoblast growth nor viability under standard culture condition (data not shown).

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PMC11190538

This test is based on MTT cleavage by mitochondrial dehydrogenases from viable cells .

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PMC10253973

The Ru(II) complex with polypyridine ligand 55 (Figure 20) may reduce the toxic effects of β-amyloid because it has the ability to trap Cu(II) ions, which cause the formation of β-amyloid aggregates.

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PMC11777207

We found no defect in DC migration in the presence of αPD-1 pembrolizumab, suggesting that the interaction between PD-1 and PD-L1 in cis (35) did not regulate DC migration (Fig. 1B).

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PMC10919056

This difference may be due to the loss of channel function, which leads to a decrease in tumor inhibition ability (usually called tumor dormancy) (28, 29), and this inhibition ability depends on the function of gap junction coupling among cells (30).

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PMC11087766

The fact that these latter proteins only localize to their cognate nucleus demonstrates that these phages can discriminate between closely related homologs with significant sequence identity, suggesting the existence of phage-specific import recognition signals.

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PMC11760643

For all analyses, differences were considered significant if p < 0.05.

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PMC6835428

Notably, a recent meta-analysis showed that IP administration significantly improved progression-free survival in advanced HGSOC patients compared to systemic administration .

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PMC9096373

The possible mechanisms of APA combined with RT.

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PMC11754784

The study was approved by the Ethics Committee at Renji Hospital, School of Medicine, Shanghai Jiao Tong University (protocol number: KY2024-070-C).

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PMC3203927

The above genes may play other roles besides being factors involved with hypoxia induced angiogenesis.

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PMC9065483

By the same token, inhibition of EGFR by genetic or pharmacological means has also been reported to activate the interferon pathway in several contexts.

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PMC9429973

Methods: Retrospective analysis of requests for plasma transfusion in adults, in our institution, between January/2020 and January/2022, This audit was undertaken to determine current use of FFP and to see if any improvements in the use of this component in relation to recommended guidance.

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PMC11705547

Recent evidence have shown that cisplatin can inhibit cancer progression by activating anti-tumor immune responses .

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PMC11344246

RO-3306, Apcin, and DCZ0415 were purchased from MedChemExpress.

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