OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11380454	AS101 and SAS decreased PD-L1 expression in these cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "AS101", "and", "SAS", "decreased", "PD-L1", "expression", "in", "these", "cells", "." ] } ]
PMC10565698	A. Expression of circUSP10 in 67 paired liver cancer and para-cancerous tissues.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A.", "Expression", "of", "circUSP10", "in", "67", "paired", "liver", "cancer", ...
PMC11680049	The inhibitory effect on Fusarium oxisporum was noted when 200 mg/L of Sequoia extract was added to the nutrient medium.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "inhibitory", "effect"...
PMC9952933	All cell types were slightly reduced in their motility following CAP treatment, although this effect was not statistically significant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "cell", "types", ...
PMC9429973	Therefore, new targeted therapies are needed to overcome drug resistance and improve treatment effectiveness.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "new", "targeted", "therapies", "are", "ne...
PMC11678130	Compared to the control, 10 µM of QUE increased the number of nuclei presenting apoptotic-like features (e.g., chromatin condensation, shrinkage, and dismorphology) and elevated the apoptotic index value.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10878518	Thus, OBP-401-mediated GFP expression is a promising biomarker for predicting the virus-mediated cytopathic efficacy in human bone and soft-tissue sarcoma cells. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ...
PMC11087766	Two FOVs were excluded from the analysis due to sample drift.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Two", "FOVs", "were", "excluded", "from", "the", "analysis", "due", "to", "sample", ...
PMC9429973	Despite high remission rates, the 5-year overall survival (OS) is <50% and <20% for<60-year-old a ≥60-year-old patients, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11122631	Subfraction D4D (294.2 mg) was subjected to silica gel CC using hexanes/methylene chloride/methanol (70/20/1 to 0/0/1) as the eluent, and a prostanoid-enriched fraction D4D2 was obtained.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8750422	siRNAs and non-targeting controls at a concentration of 100 nM were transfected into lung cancer cells using Lipofectamin 2000 in Opti-MEM medium.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "siRNAs", "an...
PMC3164356	However, CHO cells do not produce the bisecting GlcNAc branch, which is found on about 10% of human IgG glycoforms.	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	Of 38 evaluable pts, 15 pts (39%) achieved CR/CRi with at least one subsequent salvage therapy (CR=13%, CRi=26%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11578343	We report an all‐electronics‐based, microfluidic platform—multi‐zone visco‐NPS (mz‐visco‐NPS)—that enables true single‐cell viscoelastic measurements.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "report", "an", "all‐electronics‐based", ",", "mi...
PMC9275501	Schematic representation of the carrier-free nanoparticles (NPs) via co-assembly between UA and MTX.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Schematic", "representation", "of", "the", "carrier-free", "nanop...
PMC10578720	Besides, human THP-1 macrophages treated with NR alone exhibited no significant changes in the secretion of anti-inflammatory cytokines (TGF-β1 and IL-10) compared to untreated cells.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11317131	Hyperactive integrases inserted a 15.7 kb therapeutic DNA cargo containing von Willebrand Factor.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hyperactive", "integrases", "inserted", "a", "15.7", "kb", "therapeutic", "...
PMC9429973	To ensure a minimum of 1 year follow-up for all patients, data were available through July 2021.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "ensure", "a", "minimum", "of", ...
PMC7215722	Flot2 appeared primarily in the upper three fractions of the gradient and, to a lesser extent, in fractions 4-7.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Flot2",...
PMC11760643	To determine if the anti‐P2X7 mAb can mediate CDC in leukocytes, human PBMCs were incubated with either the anti‐P2X7 or isotype control mAb in the presence of complement for 2 h. Cell subsets were analysed by flow cytometry using the same gating strategies as above, with the number of cells quantified using count bead...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11755519	In 2020, urinary bladder cancer was the sixth most common cancer and the ninth leading cause of cancer deaths among men.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "2020",...
PMC9429973	Furthermore, the results also showed that the expression of Bax was significantly reduced, and the expression of Bcl-2 was increased after intervention with different concentrations of Drp-1 inhibitor Mdivi-1 (all P<0.05).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11627060	–(c) Flow cytometry analysis of the cytotoxic effect of TQ-BSA NPs in A549 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "–(c", ")", "Flow", "cytometry", "analysis", "of", ...
PMC11295144	Cooperative interaction between GABAARs and NL2 is mediated by the γ2 subunit intracellular loop. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cooperative", "interaction", "between", "GABAARs", "and", "NL2", ...
PMC9429973	I. Vaxman, S. Kumar, F. buadi, M. Lacy, D. Dingli, A. Fonder, M. Hobbs, S. Hayman, L. Y. hwa, T. Kouralis, R. Warsame, E. Muchtar, L. Nelson, P. Kapoor, M. Grogan, R. Go, W. Gonsalves, M. Siddiqi, K. Robert, V. Rajkumar, M. Gertz, A. Dispenzieri hematology, Mayo Clinic, Rochester, United States of America; hematology, ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11705901	The PCR products containing the gene fragment were digested by the corresponding restriction enzyme as listed in Table 1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "PCR", "products", "contain...
PMC11544771	Interestingly, pretreatment with PRE (20 nM) enhanced p-Chk1 (S345) induced by low concentrations of CPX (2.5–5 μM), but inhibited this phosphorylation induced by high concentrations of CPX (10–20 μM) (Figure 3 and Figure S1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11047729	Clinical data showed that melatonin displays an anti-leukemic effect in primary MLL-r leukemia blasts ex vivo.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Clinical", "data", "showed", "that", "melatonin", "dis...
PMC9672323	There are conflicting data regarding the effect of NSAIDs on TGF-β production.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "are", "conflicting", "data", "regarding", "the", "effect", "of", "NSAID...
PMC11472569	The dimerization of ABCG2 is essential for its transport activity, as the NBDs must dimerize to form a functional structure necessary for ATP binding and hydrolysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11650848	We first focussed on data from the WISC-IV clinical assessment tool, where previously collected data including scores for Full Scale IQ, as well as Verbal Comprehension and Processing Speed, where the latter includes the subtests symbol search and cancellation .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11354239	The presence of point mutations in the MS4A1 gene encoding CD20, such as (S97F; TCC→TTC) and (V247I; GTT→ATT), has been reported as being associated with decreased CD20 expression after RTX therapy in B cell lymphoma .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10335954	D Kaplan–Meier analysis of progression-free survival data with the log-rank test P-values indicated Altered TRIP13 in the cells from stomach cancer and its in vitro and in vivo effect on tumorigenic properties.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11519583	The amount of the plasmids transfected was adjusted to 9 μg (left) or 11 μg (right) in total with empty (mock) plasmid.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7504302	Although not feasible for testing therapeutic strategies aiming to reactivate TP53 and PTEN pathways, the rapid onset and short latency period of these tumor models and the frequent deregulation of therapeutically viable signaling pathways make this GEM model suitable for preclinical applications .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Moreover, circulating lncRNAs have already been proposed as a new class of non-invasive biomarkers for cancer diagnosis and prognosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "circulating...
PMC11700340	C-FLIP mutations confer resistance to death receptor ligands and chemotherapeutic drugs in cancer cells [31-33], Furthermore, Hsp90 has been shown to control the stability of client proteins, including HER2, CD4, AKT, RAF-1, and Bcr-Abl, which play a vital role in the proliferation of cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11770130	The mass tolerances were 10 ppm for precursor and fragment Mass Tolerance 0.05 Da.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mass", "tolerances", "were", "10", "ppm", "for", "precurs...
PMC9429973	Overall, they were mostly pediatric patients (61.8%), males (52%), and in first complete remission (58.7%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10253973	Complex 49 (Figure 17) has effective anticancer properties towards MCF-7 cells but is less active against human glioblastoma cells (U251N).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	However, recombinant proteins did not showed effects on AML blasts neither on proliferation, nor under chemotherapy treatments supporting these factors being fundamental in the control of HSCs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11422497	Current research suggests that circRNAs primarily function as competitive endogenous RNAs (ceRNAs) by binding to microRNAs (miRNAs), thereby silencing or degrading the target miRNAs and relieving their regulation on downstream target genes, thus exerting regulatory functions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8345486	Reduced cell growth rate was observed in the culture medium containing compound 2; the growth rate decreased by almost 40% in A2780cis cells (Figure 8A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11478724	After staining with the Annexin V/FITC/PI apoptosis detection kit, the BD FACSCalibur flow cytometer was used to analyze the data, which was processed using FlowJo.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5330095	CBD inhibited HCV replication by 86.4% at a single concentration of 10 μM with EC50 of 3.163 μM in a dose-response assay.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CBD", ...
PMC11237030	To generate CHO-K1/AQP5 cells, CHO-K1 cells were transfected with a pCMV3-N-HIS-hAQP5 plasmid (#HG14696-NH, Sino Biological) that carries a hygromycin B resistance gene for selection of mammalian cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11634027	Moreover, deletion of the D motif renders Ds insensitive to altered Lft expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "deletion", "of", "the", "D", "motif", "renders"...
PMC11349530	For example, in patients with advanced pancreatic cancer (NCT02767557), the addition of tocilizumab (an anti-IL-6R antibody) to gemcitabine/nab-paclitaxel did not result in improved overall survival rate at 6 and 24 months, although more patients were alive at 18 months in the gemcitabine/nab-paclitaxel/tocilizumab gro...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	AML is characterized by a fast clonal expansion of premature myeloid cells with highly variable combinations of chromosomal aberrations and somatic mutations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "AML", "is", ...
PMC11766309	With respect to the stromal score, YKT6 had the greatest positive correlations with the stromal scores in LAML, LGG, READ, and UVM (Figure 7C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9786247	Our results show that milk isolates replicated with nearly the same efficiency in bovine udder epithelial cells than bovine isolates with other origins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Our", ...
PMC10808409	Q1: shows necrotic cells, Q2: shows later period apoptotic cells, Q3: shows normal cells, Q4: shows early apoptotic cells. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10158546	We detected positive seeding activity through increased ThT fluorescence over reaction time (40 h) across all of the conditions tested (Figure 6b).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC8193046	The ABCB1-overexpressing A2780/ADR cells were delivered by European Collection of Animal Cell Culture (ECACC, no. 93112520) and cultivated using RPMI-1640 medium (PAN-Biotech GmbH, Aidenbach, Germany) complemented with fetal bovine serum (FCS; 10%; PAN-Biotech GmbH, Aidenbach, Germany), streptomycin (50 µg/µL; PAN-Biot...	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11695623	The difference of DCUN1D5 protein expression in cancer and paracancerous tissues in UALCAN database. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "difference", "of", "DCUN1D5", "protein", "expression", ...
PMC3122064	IP was performed with a mixture of agarose conjugated anti-p53 (DO1 & FL-393, Santa Cruz, CA, USA) as described previously.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC8382973	Given the sustained high rate of HIV infection, a gap remains for education, improved compliance, and recognition of condom usage.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Given",...
PMC11429241	The A2780 cell line does not form 3D cultures as easily as the SKOV3 line.	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "The", "A2780", "cell", "line", "does", "not", ...
PMC11803210	Fig 1Table 1Top 5 pathways from upregulated genes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig", "1Table", "1Top", "5", "pathways", "from", "upregulated", "genes", "." ] } ]
PMC9952933	The viability of HOBs was less affected by CAP treatment and is significantly different from A673 cells after only 5 s and 10 s of treatment.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC10297204	Surgical tumor resection with a wide margin has been widely accepted as the main treatment strategy for STSs .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Surgical", "tumor", "resection", "with", ...
PMC10654497	The statistical significance was set to P < 0.05, and the significance levels were expressed as P < 0.05, P < 0.01, P <0.001, and **P < 0.0001.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11748335	When we divided tumor-loss short LOCKs into upregulated and hypermethylated groups, we found that the upregulated group contained a higher proportion of poised promoters.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	PB immune profiling revealed a positive association of BL counts of B cells (p<0.01), CD4 T cells (p=0.02), and CD4 effector memory (EM) cells (p=0.03) with response.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11607638	Controls were injected with DEPC water (N = 20).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Controls", "were", "injected", "with", "DEPC", "water", "(", "N", "=", "20", ")...
PMC11754094	N and C indicate the amino-terminal and carboxy-terminal ends, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "N", "and", "C", "indicate", "the", "amino-terminal", "and", "carboxy-terminal", "ends", ...
PMC11190538	As a result, natural pigments and Spirulina as a source of color are becoming increasingly popular, notably in the food and cosmetics industries .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	Safety: Total Midos cycles 548 (median 2), 20 pt (11.5%) suffered QT prolongation, 26pt (14,8%) Midos interruption and 10pt (5.7%) Midos reduction.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11742431	TCGA database analysis of PD‐L1 gene expression levels in various stages of bladder cancer. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TCGA", "database", "analysis", "of", "PD‐L1", "gene", "expr...
PMC11591794	After incubation, the cell medium was changed and different concentrations of DOX and GA were added to the wells containing the cells and incubated for 24, 48, and 72 h. After the incubation, the medium in the wells was removed and the MTT solution (20 μL) prepared in sterile PBS was added to each well; the microplates...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11748335	= not significant).	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "=", "not", "significant", ")", "." ] } ]
PMC11632064	Using STRING, we also performed a protein-protein interaction analysis of the whole mitochondrial transcript signature.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Using", "STRING", ",", "we", "also", "performed", ...
PMC8873393	In order to examine the transcription shutdown and recovery in accordance with DNA repair process, we grouped the expressed genes in the chromatin fraction into “recovered genes” (expression levels were reduced 30 min after UV irradiation and restored to normal levels 3 h or 24 h post-irradiation) and “not recovered ge...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9268620	In some cells, the protuberances separated from the cell of origin, producing apoptotic bodies of varying sizes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "some", "cells", ",", ...
PMC11693599	Both adherent cells and CSC-derived EVs were highly enriched in CD9 and CD81, which have been reported as exosomal markers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Both", "adherent", ...
PMC11092382	Overall, as a natural compound, sophocarpine has promising potential in the field of cancer treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Overall", ",", "as", "a", "natural", "compo...
PMC11792888	Here we show that venom from R. junceus scorpion is more effective at reducing cell viability of non-small cell lung cancer (NSCLC) cells compared to the non-cancerous counterparts.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10560648	Cell survival comparison in Jurkat and normal lymphocytes at different concentrations in 24h.	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "survival", "comparison", "in", "Jurkat", "and", "normal", ...
PMC10772747	The sample was identified and authenticated at Materia Medika Laboratory Malang with collection number 074/348/102.7/2021.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "sample", "was", "identified", "and", "authenticated", ...
PMC11562028	It is similar to the trend of cell suppression in Fig. 2B.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "similar", "to", "the", "trend", "of", "cell", "suppression", "...
PMC7709199	Two well known inhibitors are kifunensine and swainsonine, which halt N-glycosylation by inhibiting ER-resident α-mannosidase I and Golgi-resident α-mannosidase II, respectively (Elbein et al., 1982 ▸, 1990 ▸).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7642379	On the other hand, the adherent cell-lines 293E and 293T showed larger variations in gene expression patterns between cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": ...
PMC9872547	It has been shown that the reduction of intracellular glutathione in cancer cells by buthionine sulfoximine increases ROS levels and makes these cells more sensitive to curcumin (23).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11765988	Although fine-needle aspiration and core needle biopsy are often employed during the initial evaluation of adenopathy, these methods do not provide sufficient tissue for a definitive lymphoma diagnosis, particularly for verifying Hodgkin’s lymphoma, which requires the identification of Reed-Sternberg cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11225860	Fluorescent markers were introduced with lentiviruses to generate stable cell lines expressing Geminin-clover (S/G2/M) and cdt1-mKO (G1), which can be monitored overtime in the green and red channels respectively of an Incucyte S3 (Essen) imaging system.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Primary end point was safety, including DLTs and AEs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Primary", "end", "point", "was", "safety", ",", "including", "DLTs", "and", "AEs", "." ...
PMC11082662	Approximately 2×10 cells suspended in 100 µL of serum-free medium were added to the upper chamber, while the lower chamber was supplemented with 600 µL of DMEM containing 20% FBS to induce chemotaxis, prompting tumor cells to migrate toward the nutrient-rich lower chamber.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4270159	Please see Power Calculations for details.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Please", "see", "Power", "Calculations", "for", "details", "." ] } ]
PMC11055323	We next performed half-FRAP assay to probe the nature of SS18/SS18-SSX condensates and show that the unbleached half condensates exhibit distinct molecular dynamics (Fig. 1e), suggesting that the mechanism of SS18-SSX condensate formation might be closer to low-valency interactions with spatially clustered binding site...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	One pt (6%; 3 to <6 mo) had grade ≥3 headache; 5 (13%; <3 mo), 2 (11%; 3 to <6 mo), and 2 (12.5%; 6 to ≤12 mo) pts had grade ≥3 thrombocytopenia.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10968586	In an in vivo B16F10 (mouse melanoma cell line) allograft model of high-fat diet (HFD)-induced melanoma progression in C57BL/6N mice, HFD containing 0.02% and 0.04% OLE reduced HFD-driven tumor growth and lymph node metastasis, with a mechanism involving (I) inhibition of cell proliferation, as indicated by the reducti...	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "...
PMC11750161	The PMSG enzyme-linked immunosorbent assay (ELISA) kit was purchased from DRG International (Mountainside, NJ, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "PMSG", "en...
PMC10899471	It was found that BATF2 mRNA and protein levels were significantly decreased in 12 cases of sarcoma tissues, compared to the corresponding adjacent tissues ( Figures 1A, B ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11453018	To explore this, we leveraged previously published high-resolution ChIP-Seq data obtained from studies examining the epigenetic effects of gain and loss of EWS::FLI1 function in ES and MCS .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7602170	Usually, the shape of the tumor is described as nodular, lobulated or bosselated with well circumscribed borders .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Usually", ",", "the", "shape", ...
PMC11092382	Furthermore, the insufficiency of clinical trials on sophocarpine in mammals and humans needs to be addressed to facilitate its clinical application.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ...
PMC9429973	Exonic, intronic and flanking regions of the HBB gene, as well as distant regulatory areas on the beta globin locus control region (LCR) may be affected.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11790971	a–c Classification performance for each passage using individual imaging modalities (i.e., 2PF, 3PF, THG) and combinations of imaging modalities (i.e., SLAM, FLIM, SLAM + FLIM).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11087766	Error bars indicate SD. **	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Error", "bars", "indicate", "SD", ".", "", "" ] } ]
PMC9429973	Mean baseline values of PROs reflected the deep impairment of pts’ HRQoL at MM diagnosis and were similar in the two arms.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mean", ...

PMC11380454

AS101 and SAS decreased PD-L1 expression in these cells.

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PMC10565698

A. Expression of circUSP10 in 67 paired liver cancer and para-cancerous tissues.

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PMC11680049

The inhibitory effect on Fusarium oxisporum was noted when 200 mg/L of Sequoia extract was added to the nutrient medium.

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PMC9952933

All cell types were slightly reduced in their motility following CAP treatment, although this effect was not statistically significant.

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PMC9429973

Therefore, new targeted therapies are needed to overcome drug resistance and improve treatment effectiveness.

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PMC11678130

Compared to the control, 10 µM of QUE increased the number of nuclei presenting apoptotic-like features (e.g., chromatin condensation, shrinkage, and dismorphology) and elevated the apoptotic index value.

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PMC10878518

Thus, OBP-401-mediated GFP expression is a promising biomarker for predicting the virus-mediated cytopathic efficacy in human bone and soft-tissue sarcoma cells. (

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PMC11087766

Two FOVs were excluded from the analysis due to sample drift.

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PMC9429973

Despite high remission rates, the 5-year overall survival (OS) is <50% and <20% for<60-year-old a ≥60-year-old patients, respectively.

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PMC11122631

Subfraction D4D (294.2 mg) was subjected to silica gel CC using hexanes/methylene chloride/methanol (70/20/1 to 0/0/1) as the eluent, and a prostanoid-enriched fraction D4D2 was obtained.

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PMC8750422

siRNAs and non-targeting controls at a concentration of 100 nM were transfected into lung cancer cells using Lipofectamin 2000 in Opti-MEM medium.

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PMC3164356

However, CHO cells do not produce the bisecting GlcNAc branch, which is found on about 10% of human IgG glycoforms.

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PMC9429973

Of 38 evaluable pts, 15 pts (39%) achieved CR/CRi with at least one subsequent salvage therapy (CR=13%, CRi=26%).

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PMC11578343

We report an all‐electronics‐based, microfluidic platform—multi‐zone visco‐NPS (mz‐visco‐NPS)—that enables true single‐cell viscoelastic measurements.

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PMC9275501

Schematic representation of the carrier-free nanoparticles (NPs) via co-assembly between UA and MTX.

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PMC10578720

Besides, human THP-1 macrophages treated with NR alone exhibited no significant changes in the secretion of anti-inflammatory cytokines (TGF-β1 and IL-10) compared to untreated cells.

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PMC11317131

Hyperactive integrases inserted a 15.7 kb therapeutic DNA cargo containing von Willebrand Factor.

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PMC9429973

To ensure a minimum of 1 year follow-up for all patients, data were available through July 2021.

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PMC7215722

Flot2 appeared primarily in the upper three fractions of the gradient and, to a lesser extent, in fractions 4-7.

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PMC11760643

To determine if the anti‐P2X7 mAb can mediate CDC in leukocytes, human PBMCs were incubated with either the anti‐P2X7 or isotype control mAb in the presence of complement for 2 h. Cell subsets were analysed by flow cytometry using the same gating strategies as above, with the number of cells quantified using count bead...

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PMC11755519

In 2020, urinary bladder cancer was the sixth most common cancer and the ninth leading cause of cancer deaths among men.

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PMC9429973

Furthermore, the results also showed that the expression of Bax was significantly reduced, and the expression of Bcl-2 was increased after intervention with different concentrations of Drp-1 inhibitor Mdivi-1 (all P<0.05).

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PMC11627060

–(c) Flow cytometry analysis of the cytotoxic effect of TQ-BSA NPs in A549 cells.

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PMC11295144

Cooperative interaction between GABAARs and NL2 is mediated by the γ2 subunit intracellular loop. (

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PMC9429973

I. Vaxman, S. Kumar, F. buadi, M. Lacy, D. Dingli, A. Fonder, M. Hobbs, S. Hayman, L. Y. hwa, T. Kouralis, R. Warsame, E. Muchtar, L. Nelson, P. Kapoor, M. Grogan, R. Go, W. Gonsalves, M. Siddiqi, K. Robert, V. Rajkumar, M. Gertz, A. Dispenzieri hematology, Mayo Clinic, Rochester, United States of America; hematology, ...

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PMC11705901

The PCR products containing the gene fragment were digested by the corresponding restriction enzyme as listed in Table 1.

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PMC11544771

Interestingly, pretreatment with PRE (20 nM) enhanced p-Chk1 (S345) induced by low concentrations of CPX (2.5–5 μM), but inhibited this phosphorylation induced by high concentrations of CPX (10–20 μM) (Figure 3 and Figure S1).

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PMC11047729

Clinical data showed that melatonin displays an anti-leukemic effect in primary MLL-r leukemia blasts ex vivo.

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PMC9672323

There are conflicting data regarding the effect of NSAIDs on TGF-β production.

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PMC11472569

The dimerization of ABCG2 is essential for its transport activity, as the NBDs must dimerize to form a functional structure necessary for ATP binding and hydrolysis.

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PMC11650848

We first focussed on data from the WISC-IV clinical assessment tool, where previously collected data including scores for Full Scale IQ, as well as Verbal Comprehension and Processing Speed, where the latter includes the subtests symbol search and cancellation .

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PMC11354239

The presence of point mutations in the MS4A1 gene encoding CD20, such as (S97F; TCC→TTC) and (V247I; GTT→ATT), has been reported as being associated with decreased CD20 expression after RTX therapy in B cell lymphoma .

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PMC10335954

D Kaplan–Meier analysis of progression-free survival data with the log-rank test P-values indicated Altered TRIP13 in the cells from stomach cancer and its in vitro and in vivo effect on tumorigenic properties.

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PMC11519583

The amount of the plasmids transfected was adjusted to 9 μg (left) or 11 μg (right) in total with empty (mock) plasmid.

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PMC7504302

Although not feasible for testing therapeutic strategies aiming to reactivate TP53 and PTEN pathways, the rapid onset and short latency period of these tumor models and the frequent deregulation of therapeutically viable signaling pathways make this GEM model suitable for preclinical applications .

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PMC9429973

Moreover, circulating lncRNAs have already been proposed as a new class of non-invasive biomarkers for cancer diagnosis and prognosis.

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PMC11700340

C-FLIP mutations confer resistance to death receptor ligands and chemotherapeutic drugs in cancer cells [31-33], Furthermore, Hsp90 has been shown to control the stability of client proteins, including HER2, CD4, AKT, RAF-1, and Bcr-Abl, which play a vital role in the proliferation of cancer cells.

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PMC11770130

The mass tolerances were 10 ppm for precursor and fragment Mass Tolerance 0.05 Da.

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PMC9429973

Overall, they were mostly pediatric patients (61.8%), males (52%), and in first complete remission (58.7%).

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PMC10253973

Complex 49 (Figure 17) has effective anticancer properties towards MCF-7 cells but is less active against human glioblastoma cells (U251N).

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PMC9429973

However, recombinant proteins did not showed effects on AML blasts neither on proliferation, nor under chemotherapy treatments supporting these factors being fundamental in the control of HSCs.

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PMC11422497

Current research suggests that circRNAs primarily function as competitive endogenous RNAs (ceRNAs) by binding to microRNAs (miRNAs), thereby silencing or degrading the target miRNAs and relieving their regulation on downstream target genes, thus exerting regulatory functions.

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PMC8345486

Reduced cell growth rate was observed in the culture medium containing compound 2; the growth rate decreased by almost 40% in A2780cis cells (Figure 8A).

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PMC11478724

After staining with the Annexin V/FITC/PI apoptosis detection kit, the BD FACSCalibur flow cytometer was used to analyze the data, which was processed using FlowJo.

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PMC5330095

CBD inhibited HCV replication by 86.4% at a single concentration of 10 μM with EC50 of 3.163 μM in a dose-response assay.

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PMC11237030

To generate CHO-K1/AQP5 cells, CHO-K1 cells were transfected with a pCMV3-N-HIS-hAQP5 plasmid (#HG14696-NH, Sino Biological) that carries a hygromycin B resistance gene for selection of mammalian cell lines.

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PMC11634027

Moreover, deletion of the D motif renders Ds insensitive to altered Lft expression.

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PMC11349530

For example, in patients with advanced pancreatic cancer (NCT02767557), the addition of tocilizumab (an anti-IL-6R antibody) to gemcitabine/nab-paclitaxel did not result in improved overall survival rate at 6 and 24 months, although more patients were alive at 18 months in the gemcitabine/nab-paclitaxel/tocilizumab gro...

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PMC9429973

AML is characterized by a fast clonal expansion of premature myeloid cells with highly variable combinations of chromosomal aberrations and somatic mutations.

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PMC11766309

With respect to the stromal score, YKT6 had the greatest positive correlations with the stromal scores in LAML, LGG, READ, and UVM (Figure 7C).

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PMC9786247

Our results show that milk isolates replicated with nearly the same efficiency in bovine udder epithelial cells than bovine isolates with other origins.

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PMC10808409

Q1: shows necrotic cells, Q2: shows later period apoptotic cells, Q3: shows normal cells, Q4: shows early apoptotic cells. (

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PMC10158546

We detected positive seeding activity through increased ThT fluorescence over reaction time (40 h) across all of the conditions tested (Figure 6b).

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PMC8193046

The ABCB1-overexpressing A2780/ADR cells were delivered by European Collection of Animal Cell Culture (ECACC, no. 93112520) and cultivated using RPMI-1640 medium (PAN-Biotech GmbH, Aidenbach, Germany) complemented with fetal bovine serum (FCS; 10%; PAN-Biotech GmbH, Aidenbach, Germany), streptomycin (50 µg/µL; PAN-Biot...

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PMC11695623

The difference of DCUN1D5 protein expression in cancer and paracancerous tissues in UALCAN database. (

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PMC3122064

IP was performed with a mixture of agarose conjugated anti-p53 (DO1 & FL-393, Santa Cruz, CA, USA) as described previously.

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PMC8382973

Given the sustained high rate of HIV infection, a gap remains for education, improved compliance, and recognition of condom usage.

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PMC11429241

The A2780 cell line does not form 3D cultures as easily as the SKOV3 line.

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PMC11803210

Fig 1Table 1Top 5 pathways from upregulated genes.

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PMC9952933

The viability of HOBs was less affected by CAP treatment and is significantly different from A673 cells after only 5 s and 10 s of treatment.

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PMC10297204

Surgical tumor resection with a wide margin has been widely accepted as the main treatment strategy for STSs .

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PMC10654497

The statistical significance was set to P < 0.05, and the significance levels were expressed as *P < 0.05, **P < 0.01, ***P <0.001, and ****P < 0.0001.

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PMC11748335

When we divided tumor-loss short LOCKs into upregulated and hypermethylated groups, we found that the upregulated group contained a higher proportion of poised promoters.

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PMC9429973

PB immune profiling revealed a positive association of BL counts of B cells (p<0.01), CD4 T cells (p=0.02), and CD4 effector memory (EM) cells (p=0.03) with response.

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PMC11607638

Controls were injected with DEPC water (N = 20).

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PMC11754094

N and C indicate the amino-terminal and carboxy-terminal ends, respectively.

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PMC11190538

As a result, natural pigments and Spirulina as a source of color are becoming increasingly popular, notably in the food and cosmetics industries .

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PMC9429973

Safety: Total Midos cycles 548 (median 2), 20 pt (11.5%) suffered QT prolongation, 26pt (14,8%) Midos interruption and 10pt (5.7%) Midos reduction.

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PMC11742431

TCGA database analysis of PD‐L1 gene expression levels in various stages of bladder cancer. (

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PMC11591794

After incubation, the cell medium was changed and different concentrations of DOX and GA were added to the wells containing the cells and incubated for 24, 48, and 72 h. After the incubation, the medium in the wells was removed and the MTT solution (20 μL) prepared in sterile PBS was added to each well; the microplates...

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PMC11748335

= not significant).

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PMC11632064

Using STRING, we also performed a protein-protein interaction analysis of the whole mitochondrial transcript signature.

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PMC8873393

In order to examine the transcription shutdown and recovery in accordance with DNA repair process, we grouped the expressed genes in the chromatin fraction into “recovered genes” (expression levels were reduced 30 min after UV irradiation and restored to normal levels 3 h or 24 h post-irradiation) and “not recovered ge...

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PMC9268620

In some cells, the protuberances separated from the cell of origin, producing apoptotic bodies of varying sizes.

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PMC11693599

Both adherent cells and CSC-derived EVs were highly enriched in CD9 and CD81, which have been reported as exosomal markers.

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PMC11092382

Overall, as a natural compound, sophocarpine has promising potential in the field of cancer treatment.

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PMC11792888

Here we show that venom from R. junceus scorpion is more effective at reducing cell viability of non-small cell lung cancer (NSCLC) cells compared to the non-cancerous counterparts.

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PMC10560648

Cell survival comparison in Jurkat and normal lymphocytes at different concentrations in 24h.

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PMC10772747

The sample was identified and authenticated at Materia Medika Laboratory Malang with collection number 074/348/102.7/2021.

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PMC11562028

It is similar to the trend of cell suppression in Fig. 2B.

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PMC7709199

Two well known inhibitors are kifunensine and swainsonine, which halt N-glycosylation by inhibiting ER-resident α-mannosidase I and Golgi-resident α-mannosidase II, respectively (Elbein et al., 1982 ▸, 1990 ▸).

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PMC7642379

On the other hand, the adherent cell-lines 293E and 293T showed larger variations in gene expression patterns between cell lines.

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PMC9872547

It has been shown that the reduction of intracellular glutathione in cancer cells by buthionine sulfoximine increases ROS levels and makes these cells more sensitive to curcumin (23).

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PMC11765988

Although fine-needle aspiration and core needle biopsy are often employed during the initial evaluation of adenopathy, these methods do not provide sufficient tissue for a definitive lymphoma diagnosis, particularly for verifying Hodgkin’s lymphoma, which requires the identification of Reed-Sternberg cells .

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PMC11225860

Fluorescent markers were introduced with lentiviruses to generate stable cell lines expressing Geminin-clover (S/G2/M) and cdt1-mKO (G1), which can be monitored overtime in the green and red channels respectively of an Incucyte S3 (Essen) imaging system.

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PMC9429973

Primary end point was safety, including DLTs and AEs.

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PMC11082662

Approximately 2×10 cells suspended in 100 µL of serum-free medium were added to the upper chamber, while the lower chamber was supplemented with 600 µL of DMEM containing 20% FBS to induce chemotaxis, prompting tumor cells to migrate toward the nutrient-rich lower chamber.

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PMC4270159

Please see Power Calculations for details.

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PMC11055323

We next performed half-FRAP assay to probe the nature of SS18/SS18-SSX condensates and show that the unbleached half condensates exhibit distinct molecular dynamics (Fig. 1e), suggesting that the mechanism of SS18-SSX condensate formation might be closer to low-valency interactions with spatially clustered binding site...

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PMC9429973

One pt (6%; 3 to <6 mo) had grade ≥3 headache; 5 (13%; <3 mo), 2 (11%; 3 to <6 mo), and 2 (12.5%; 6 to ≤12 mo) pts had grade ≥3 thrombocytopenia.

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PMC10968586

In an in vivo B16F10 (mouse melanoma cell line) allograft model of high-fat diet (HFD)-induced melanoma progression in C57BL/6N mice, HFD containing 0.02% and 0.04% OLE reduced HFD-driven tumor growth and lymph node metastasis, with a mechanism involving (I) inhibition of cell proliferation, as indicated by the reducti...

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PMC11750161

The PMSG enzyme-linked immunosorbent assay (ELISA) kit was purchased from DRG International (Mountainside, NJ, USA).

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PMC10899471

It was found that BATF2 mRNA and protein levels were significantly decreased in 12 cases of sarcoma tissues, compared to the corresponding adjacent tissues ( Figures 1A, B ).

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PMC11453018

To explore this, we leveraged previously published high-resolution ChIP-Seq data obtained from studies examining the epigenetic effects of gain and loss of EWS::FLI1 function in ES and MCS .

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PMC7602170

Usually, the shape of the tumor is described as nodular, lobulated or bosselated with well circumscribed borders .

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PMC11092382

Furthermore, the insufficiency of clinical trials on sophocarpine in mammals and humans needs to be addressed to facilitate its clinical application.

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PMC9429973

Exonic, intronic and flanking regions of the HBB gene, as well as distant regulatory areas on the beta globin locus control region (LCR) may be affected.

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PMC11790971

a–c Classification performance for each passage using individual imaging modalities (i.e., 2PF, 3PF, THG) and combinations of imaging modalities (i.e., SLAM, FLIM, SLAM + FLIM).

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PMC11087766

Error bars indicate SD. **

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PMC9429973

Mean baseline values of PROs reflected the deep impairment of pts’ HRQoL at MM diagnosis and were similar in the two arms.

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