OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11802929	We also defined phenotype scores as: Cytotoxic score (GZMB, GZMA, GNLY, PRF1) and Naïve-Memory score (TCF7, CCR7, SELL, LEF1, GZMK, IL7R).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8557138	For example, Michael et al., implanted fragments of Brown-Pearce epithelioma and V2 carcinoma into rabbit corneal stroma and demonstrated the process of neovascularization in an avascular site (Gimbrone Jr. et al. 1974).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7348793	It is conceivable that the co-amplification of the nuclear mitochondrial sequences (NUMTs) containing an alternative number of repeats can manifest itself as mtDNA length heteroplasmy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9504875	A similar pattern was reported in the 3B protein of foot-and-mouth disease virus, although this protein does not bind to TRIM25 but rather directly binds to RIG-I .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11519788	Student's t test was used to compare the differences between two groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Student", "'s", "t", "test", "was", "used", "to", "compare", "the", ...
PMC11538390	b Correlation between the regional allele frequency of rs570516915 and prevalence of CP.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "b", "Correlation", "between", "the", "regional", "allele", "frequency", "of...
PMC10723784	The IC50 values have been summarized in Table 4.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "IC50", "values", "have", "been", "summarized", "in", "Table", "4", "." ] } ]
PMC11694066	This plating density was optimized to ensure that the cells were in growth phase by the end of the 5-day treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "plating", ...
PMC10380508	The GEPIA website (available at http://gepia.cancer-pku.cn/, accessed on 20 December 2022) is an online resource to analyze clinical data from TCGA database and tissue-specific expression patterns .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11185260	Human ATRT cell line CHLA-06 and human rhabdomyosarcoma cell lines A-204 and Hs729 were obtained from the American Type Culture Collection (Manassas, VA, USA).	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC11770130	The pair-fed Ntsr2 AKO mice also had a better performance in the GTT (Fig. 2c) and ITT (Fig. 2d).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC11615218	Upon antigenic stimulation, CD4 T cells undergo proliferation and secretion of cytokines that stimulate antibody responses or lead to macrophage activation via interactions with class II MHC molecules, whereas CD8 T cells kill the antigen-bearing cells through class I MHC molecules .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4839679	Therefore, ccRCC patients without mutated PBRM1 may have alterations in different genes that affect the same pathways, making the mutational status of PBRM1 irrelevant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11742670	Combination of DL with FRS theory, XAI, and medicinal chemistry to identify potential new drug candidates by analyzing the experimental results of Vidarabine natural product.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: Here we will investigate the dynamics of stress responses in the hematopoietic stem and progenitor compartment at the single-cell level, independent of the use of defined surface markers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5311252	Clinical studies have shown us that this type of targeted therapy is only efficient against tumors that rely on the targeted protein for proliferation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11066331	The model's maximum Q2Y value indicates the number of components at which overfitting begins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "model", "'s", "maximum", "Q2Y", "value", "indicates"...
PMC7039683	Browser view of the human genome, hg19, focused on this locus.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Browser", "view", "of", "the", "human", "genome", ",", "hg19", ",", ...
PMC10698968	Additionally, the presence of abundant and large rough endoplasmic reticulum, multivesicular bodies, autophagic vacuoles (av), and numerous endosomes and vesicles (v) are further signals of great endocytotic and exocytotic activities, which indicate high cell-to-cell communication (Fig. 4C, picture B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11680391	Ideally, the dairy farmer and herd veterinarian relationship is built on mutual trust and an alignment of expectations; therefore, we hypothesize that the agreement would be at least minor to moderate, and the association with BTSCC will be minor.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11802929	We graph the distribution of putative antigens against the SARS-CoV-2 genome and highlighted the 558 (58.7%) constructs that were expressed and used for the T cell capture experiment, and the 102 (18.3%) that captured at least 1 cell (Fig. 2a, Supplementary Fig. 2a).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11659921	Analysis of risk score correlation with immune infiltration‐associated cells based on the xCELL method.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Analysis", "of", "risk", "score", "correlation", "with", "immune", ...
PMC9429973	Baseline characteristics include median age 75 years, median number of prior therapies 3, 97% received prior treatment with venetoclax, 97% had prior HMA, and 43% had prior induction failure.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4395774	Based on our results showing that 10–20% WT hematopoietic chimerism is sufficient to reestablish normal immune regulation, we investigated the feasibility of HSC gene therapy for perforin deficiency.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11585994	Experimental design utilizing the T-ALL patient-derived xenograft mouse model.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Experimental", "design", "utilizing", "the", "T-ALL", "patient-derived", "xenograft", "mouse", "model", "."...
PMC11545737	This mechanism plays a role in the activation of the canonical pyroptosis pathway activation in THP-1 monocytes, since downregulation of cathepsin B downregulation reduces NLRP3 activation and IL-1β production by N. gonorrhoeae .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8922418	More recently, a clinical report on the "London patient" with Hodgkin's lymphoma and AIDS provided similar evidence of curative treatment (Gupta et al., 2019).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6617630	Co-treatment with I-BET and ABT-199 had a strong combinatorial effect with nearly complete abolition of cell survival not only in WT-MYC cell line but also DHL (DOHH2) and THL (Val) DLBCL cell lines (Fig. 8a–c).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11696576	Cancers which rely on mitochondrial fatty acid oxidation (FAO) for energy derived from oxidative phosphorylation (OXPHOS) have a high oxidative burden.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10873328	The cisplatin-resistant derivate ovarian cancer cell line A2780/CDDP was cultured in intermittent incremental exposure to cisplatin.	[ { "tags": [ "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cisplatin-resistant", "deriva...
PMC11694346	Upon reaction of BT-DNBS with biothiols, the N–S bond between the piperazine and DNBS is cleaved, which interrupts the PET process, resulting in the restoration of fluorescence.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10440586	Each column represents a sample in the TCGA dataset.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", "column", "represents", "a", "sample", "in", "the", "TCGA", "dataset", "." ] } ]
PMC9684669	To investigate the unique target of terfenadine in combinational chemotherapy for MDR cancer, the global gene expression of doxorubicin-sensitive and -resistant cell lines was profiled using RNA sequence.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11672881	These genes are involved in various processes, such as cellular stress response, transcription regulation, and reduces cell migration .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "genes", ...
PMC8524093	Released IFNs by infected cells exert an autocrine/paracrine signaling that will activate the Janus Kinase-signal transducer and activator of transcription (JAK-STAT) pathway, through binding to IFN-α/β receptors (IFNAR) (Majoros et al., 2017).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11707577	As shown in Figure 8A, treated polyps did not present signs of damage, at any time of continuous incubation, suggesting the biosafety of the engineered compound in absence of photostimulation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8469018	As the obtained tests results did not show any involvement of mitochondria in the toxicity of teriflunomide, the localization of the compound in individual cell compartments was examined, using chromatographic methods.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10998613	Taking into consideration the observation of CXCR4 homomultimerization and weak β2AR homodimerization, we conclude that the heteromeric clusters are composed of one β2AR and several CXCR4 receptors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11306019	To investigate this further, we explored whether repeated treatments to maintain concentration over time are sufficient for BTZ to exhibit its anticancer effect at this level.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11706776	TPM transcripts per million.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "TPM", "transcripts", "per", "million", "." ] } ]
PMC11388384	To test whether diffusive populations reflected known features of SHH biochemistry, we took inspiration from prior experiments, in which SHH lacking its C-terminal cholesterol was found to form longer signaling gradients compared to wild-type SHH, presumably by altering SHH interactions in the extracellular space (22).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: Here, we investigate whether BM Tfr2 targeting might represent a therapeutic option for TDT.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "Here", ",", "we", "investigate...
PMC10957991	Besides these physiological functions, TRPV4 seems to be important for the maintenance of epithelial integrity through its role in the regulation of on adherens and tight junction proteins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9587866	Therefore, in our study we adopted the safer insilico approach which uses medicinal compounds to target EYA3 to obtain good cytotoxic inhibitor for EWS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11342785	We found that TPPP variants with strong MT-association triggered the strongest MT bundling activity when targeted to DDX4-droplet hubs (e.g. C-CORE) (Figs. 3C, 6F, S2B, and S9, A–C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10919056	Transfection was performed using Lipofectamine 3000 (Invitrogen, Shanghai, China).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Transfection", "was", "performed", "using", "Lipofectamine", "3000", "(", "...
PMC10729469	After incubation, cells were centrifuged, resuspended in 4 mL 30% Percoll, layered with 4 mL HBSS, centrifuged (700xg for 10 min), and the cell pellet collected for flow staining.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10092581	Apart from the aforementioned behavior of Au(I) complexes, both Au(I) and Ag(I) complexes did not show any signs of degradation/decomposition in all the measured timepoints.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Transfusion dependence for 8 weeks was similar with 32.1% and 22.4% of the G group and 37.9% and 20.0% of the TC group being platelet transfusion or red blood cell transfusion independent, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11546117	The ESI voltage was 4 kV for all analytes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "ESI", "voltage", "was", "4", "kV", "for", "all", "analytes", "." ] } ]
PMC11727062	To date, over 40 distinct ginsenosides have been identified (Xu et al. 2021).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "date", ",", "over", "40", "distinct", "gin...
PMC11708541	Nonetheless, a growing amount of data indicated that fampridine has offered benefits in addition to its symptomatic mechanism of action (Fig. 7).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11739504	Fig. 5The acetyltransferase domain of Kat2b in the cytosol is significant for localization of IFT components at primary cilia. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "5The", "acetyltransf...
PMC10976516	Zugazagoitia et al.; Yang et al.; Wang et al.SurgeryMost cases of SCLC cannot be treated with surgery.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Zugazagoitia", "et", ...
PMC11604768	Consistent responses across the populations of barcodes suggested the induction of individual promoters following stimulation was highly reproducible.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Consistent", "responses", "across", "the", ...
PMC9577200	Moreover, we used the most efficient natural antibacterial material as an anticancer treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "we", "used", "the", "most", "efficient", "natur...
PMC10154097	THE-2 and Huh7 cells were cultured in RMPI-1640, and BEL-7404, HCCLM3, and Hep3B were cultured in DMEM (Invitrogen, USA).	[ { "tags": [ "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", ...
PMC6181431	Many variants were discarded due to misaligned reads, repetitive sequence tracts, low quality base or read scores, or reads seen in only a single direction.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7802142	a Schematic illustration of ReN-NV preparation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "a", "Schematic", "illustration", "of", "ReN-NV", "preparation", "." ] } ]
PMC11593084	PODO/TERT256 and hTCEpi were purchased from EVERCYTE (Vienna, Austria).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PODO/TERT256", "and", "hTCEpi", "were", "purchased", "from", "EVERCYTE", "(", "V...
PMC8316344	Thereby, we tested whether TRIB2 regulates TFRC protein via PSMB5.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thereby", ",", "we", "tested", "whether", "TRIB2", "regulates", "TFRC", "protein", "v...
PMC11572213	Puromycin selection was applied for 3 days, and the medium was replaced.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Puromycin", "selection", "was", "applied", "for", "3", "days", ",", "...
PMC10936243	But I think in terms of management and cost, to wash it that often and to control with the bio-security, I think that will lead to higher cost” [D063].Participants reported using alternative forms of bedding such as disposable materials (e.g. newspapers).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5839394	The emission-excitation (EEM) spectra of DNA were recorded by Luminescent Spectrometer (Perkin Elmer LS 55).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "emission-excitation", "(", ...
PMC11394730	Natural products also exhibit the ability to interfere with biosynthetic pathways critical for cancer cell survival.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Natural", "products", "also", "exhibit", "the", "abili...
PMC9592219	Finally, various binding modes were scored and sorted based on the molecular energy of docking, and the docking conformation of the molecule was determined based on the lowest docking energy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10747160	When we look solely at the raw spike ELISA signal, it appears as though the M, N, and MNE strains have higher spike incorporation per virion when compared to Wild-Type virus (Figure S8A,C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11281366	The resulting library was sequenced using a NovaSeq 6000 system (Illumina Technologies).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "resulting", "library", "was", "sequenced", "using", "a", ...
PMC11656657	Quantification of the specified cytokines, including CCL2, CCL3, CCL5, CCL7, CX3CL1, CXCL1, CXCL2, CXCL4, CXCL5, CXCL6, CXCL8 (IL8), CXCL13, CXCL14, G-CSF (CSF3), GM-CSF, IFN-gamma, IL10, IL13, IL1b, IL5, MCSF, and TNF-alpha, was normalized on blank control background for the in vitro data (in violet) and no tumor samp...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11055443	In addition to the anti-apoptotic effect of IL-6, previous studies have also shown that the MSCs soluble factors can lead to a decrease in apoptosis by reducing the activation of caspase 3 and 7 (39).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8097906	The bottom layer in each well of a 6-well plate (Sarstedt, Germany) was made with 1.5 ml of 1% agar (Sigma Aldrich, Saint Luis, USA) in assay medium and the top layer was made with 1.5 ml of 0.6% agar and 5000 cells in assay medium (i.e., 0.75 ml assay medium with 5000 cells and 0.75 ml 0.6% agarose solution).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11470381	Imaging sessions should be kept brief to prevent photo-bleaching of fluorescent proteins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Imaging", "sessions", "should", "be", "kept", "brief", "to", "prevent", "photo-b...
PMC11588085	Bubble map of pathways enriched in patient samples with low XIST expression after GSEA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Bubble", "map", "of", "pathways", "enriched", "in", "patient", "...
PMC8041314	As a first step, 93 reports between 2004 and 2021 were collected in which the evaluation of small-molecule inhibitors of ABCB1, ABCC1, and ABCG2 was described.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11592837	In drug-treated Jurkat cells, no substantial difference in the level of both Alu fragments was detected after 6 h, but then Alu fragments were observed at insignificantly higher levels compared to the control (Figure 5C,D).	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11122631	With the in silico tool InflamNat, the predicted probabilities of the positive controls (aminoguanidine and apigenin) with IC50 (inhibition for NO production) <50 μM in macrophages were in a similar range (0.621–0.657), but most of the predicted probabilities of compounds were below 0.385 (Table S16).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11743414	Acute myeloid leukemia (AML) has a poor prognosis and high heterogeneity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Acute", "myeloid", "leukemia", "(", "AML", ")", "has", "a", "poor", ...
PMC6892818	RCC lines ACHN, 786-O and A-704, and normal HRPT cells were treated with mCD40L for the indicated time periods (1.5, 3 and 6 h) and expression of TRAF1 (a), TRAF2 (b) and TRAF3 (c) was detected by immunoblotting (40 µg protein/lane) in controls (‘C’) vs. mCD40L-treated cells (‘mL’).	[ { "tags": [ "O", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4112127	Approximately 60% of CCs are extrahepatic (ECC), arising from the region of the bifurcation of the right and left hepatic ducts extending distally to the distal common bile duct .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11750161	The signal sequence region was removed from eel LH/CGR and the fragments were inserted under the VSVG-tag signal sequence of the mammalian expression vector.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11576293	In addition, we investigated compounds with potential anticancer activities to see if they may act as dual inhibitors of EGFR and VEGFR-2 in order to get insight into their biological process.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11795610	All experiments were performed independently at least triplicate and the results were expressed as the mean ± standard deviation (SD).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "exper...
PMC9429973	After a median follow-up of 19 months (mo), 6 pts out of the 25 who reached CR/CRi (24%) relapsed and 20 out of 32 (63%) pts are alive.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11612315	The IC50 values for the calcium response of GLP-1, liraglutide, exendin-4, and exendin 9–39 were 178.60, 62.19, 64.49, and 28.18 nM, respectively (Fig. 5f–h).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11534035	Cells treated with 1 μM of G1 exhibited a non-significant reduction in size.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "treated", "with", "1", "μM", "of", "G1", "exhibited", "a", ...
PMC11694346	The detailed information of materials, reagents, instruments, synthesis, spectroscopic analysis, cell culture, cytotoxicity assay, fluorescence imaging experiments are provided in the ESI.† BT-Boc (100 mg, 0.11 mmol) was dissolved in dichloromethane (3 mL) in a dried flask.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5417661	A four-parameter logistic fit of the area under the curve data between 96 and 186 h time point gave pIC50 values of 8.3 and 8.7 for NOV202 and Combretastatin A4, respectively (Figure 4D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9621239	Besides, the plasmid expressing MYC-Flag was also co-transfected with the plasmids expressing HBx-WT (pcHBx-WT), HBx-SM (pcHBx-SM), HBx-DM (pcHBx-DM) or HBx-TM (pc-HBx-TM) into Huh 7 cells for 48 h. After lysis, MYC-Flag was immunoprecipitated by the Pierce Classic Magnetic IP/Co-IP Kit using the antibody (#14793, CST,...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6163708	HH has been described to promote oncogenesis in leukemias , bladder cancer , and prostate cancer .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HH", "has", "been", "described", "to", "promote", ...
PMC11633763	The results of Western blot analysis and quantitative reverse transcription polymerase chain reaction (qRT‐PCR) showed that the expression of USP22 in osteosarcoma tissues was significantly higher than that in adjacent healthy tissues.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11753949	In both cases fixation was carried out for 20 min at room temperature.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "both", "cases", "fixation", "was", "carried", "out", "for", "20...
PMC9429973	All five Rac1 inhibitors resulted in an overall antiproliferative effect, tested at dosage around IC80.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "five", "Rac1", "inhibitors", "resulted", "in", ...
PMC11319300	This is supported by data derived from orangutans, which are thought not to encode MYEOV due to a mutation leading to a premature stop codon (Papamichos et al., 2015), yet they still have an enhancer/promoter chromatin state present in the same region (Figure 4).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11774112	The data in B are expressed as the means ± SDs (n= 6). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "data", "in", "B", "are", "expressed", "as...
PMC11098378	Such IEPs might be useful molecular tools in identifying the conserved host immunity factors they target.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Such", "IEPs", "might", "be", "useful", "molecular", ...
PMC9220170	Therefore, to determine the effect of these selenium agents on the activity of mitochondrial reductases in living cells, which makes it possible to indirectly judge the change in their proliferative properties in the presence or absence of SELENOM-KD or SELENOT-KD, we performed an MTT analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9351137	To understand the relationships between Aurora B and the CRS under investigation, we asked whether the inhibition of its kinase activity affects the recruitment of both BAF53a and TIP60 to the midbody.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11787651	The new Sciex ZenoTOF 7600, with an increased scan speed and increased sensitivity enabled by the Zeno trap, has allowed us to decrease the mass spectrometer (or analytical) run time to only 20 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11539788	mTOR signalling is often activated by the upstream kinase AKT, resulting in the nuclear translocation of phosphorylated mTOR and ultimately activating downstream effectors such as S6K1 and 4EBP1 to regulate cell proliferation, survival, metabolism and autophagy .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8633974	Half of the collected cells were spun down and seeded in new plate and maintained in the incubator.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Half", "of", "the", "collected", "cell...

PMC11802929

We also defined phenotype scores as: Cytotoxic score (GZMB, GZMA, GNLY, PRF1) and Naïve-Memory score (TCF7, CCR7, SELL, LEF1, GZMK, IL7R).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8557138

For example, Michael et al., implanted fragments of Brown-Pearce epithelioma and V2 carcinoma into rabbit corneal stroma and demonstrated the process of neovascularization in an avascular site (Gimbrone Jr. et al. 1974).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7348793

It is conceivable that the co-amplification of the nuclear mitochondrial sequences (NUMTs) containing an alternative number of repeats can manifest itself as mtDNA length heteroplasmy.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9504875

A similar pattern was reported in the 3B protein of foot-and-mouth disease virus, although this protein does not bind to TRIM25 but rather directly binds to RIG-I .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11519788

Student's t test was used to compare the differences between two groups.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Student", "'s", "t", "test", "was", "used", "to", "compare", "the", ...

PMC11538390

b Correlation between the regional allele frequency of rs570516915 and prevalence of CP.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "b", "Correlation", "between", "the", "regional", "allele", "frequency", "of...

PMC10723784

The IC50 values have been summarized in Table 4.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "IC50", "values", "have", "been", "summarized", "in", "Table", "4", "." ] } ]

PMC11694066

This plating density was optimized to ensure that the cells were in growth phase by the end of the 5-day treatment.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "plating", ...

PMC10380508

The GEPIA website (available at http://gepia.cancer-pku.cn/, accessed on 20 December 2022) is an online resource to analyze clinical data from TCGA database and tissue-specific expression patterns .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11185260

Human ATRT cell line CHLA-06 and human rhabdomyosarcoma cell lines A-204 and Hs729 were obtained from the American Type Culture Collection (Manassas, VA, USA).

[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...

PMC11770130

The pair-fed Ntsr2 AKO mice also had a better performance in the GTT (Fig. 2c) and ITT (Fig. 2d).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...

PMC11615218

Upon antigenic stimulation, CD4 T cells undergo proliferation and secretion of cytokines that stimulate antibody responses or lead to macrophage activation via interactions with class II MHC molecules, whereas CD8 T cells kill the antigen-bearing cells through class I MHC molecules .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC4839679

Therefore, ccRCC patients without mutated PBRM1 may have alterations in different genes that affect the same pathways, making the mutational status of PBRM1 irrelevant.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC11742670

Combination of DL with FRS theory, XAI, and medicinal chemistry to identify potential new drug candidates by analyzing the experimental results of Vidarabine natural product.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Aims: Here we will investigate the dynamics of stress responses in the hematopoietic stem and progenitor compartment at the single-cell level, independent of the use of defined surface markers.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC5311252

Clinical studies have shown us that this type of targeted therapy is only efficient against tumors that rely on the targeted protein for proliferation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11066331

The model's maximum Q2Y value indicates the number of components at which overfitting begins.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "model", "'s", "maximum", "Q2Y", "value", "indicates"...

PMC7039683

Browser view of the human genome, hg19, focused on this locus.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Browser", "view", "of", "the", "human", "genome", ",", "hg19", ",", ...

PMC10698968

Additionally, the presence of abundant and large rough endoplasmic reticulum, multivesicular bodies, autophagic vacuoles (av), and numerous endosomes and vesicles (v) are further signals of great endocytotic and exocytotic activities, which indicate high cell-to-cell communication (Fig. 4C, picture B).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11680391

Ideally, the dairy farmer and herd veterinarian relationship is built on mutual trust and an alignment of expectations; therefore, we hypothesize that the agreement would be at least minor to moderate, and the association with BTSCC will be minor.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11802929

We graph the distribution of putative antigens against the SARS-CoV-2 genome and highlighted the 558 (58.7%) constructs that were expressed and used for the T cell capture experiment, and the 102 (18.3%) that captured at least 1 cell (Fig. 2a, Supplementary Fig. 2a).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11659921

Analysis of risk score correlation with immune infiltration‐associated cells based on the xCELL method.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Analysis", "of", "risk", "score", "correlation", "with", "immune", ...

PMC9429973

Baseline characteristics include median age 75 years, median number of prior therapies 3, 97% received prior treatment with venetoclax, 97% had prior HMA, and 43% had prior induction failure.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC4395774

Based on our results showing that 10–20% WT hematopoietic chimerism is sufficient to reestablish normal immune regulation, we investigated the feasibility of HSC gene therapy for perforin deficiency.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11585994

Experimental design utilizing the T-ALL patient-derived xenograft mouse model.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Experimental", "design", "utilizing", "the", "T-ALL", "patient-derived", "xenograft", "mouse", "model", "."...

PMC11545737

This mechanism plays a role in the activation of the canonical pyroptosis pathway activation in THP-1 monocytes, since downregulation of cathepsin B downregulation reduces NLRP3 activation and IL-1β production by N. gonorrhoeae .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8922418

More recently, a clinical report on the "London patient" with Hodgkin's lymphoma and AIDS provided similar evidence of curative treatment (Gupta et al., 2019).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC6617630

Co-treatment with I-BET and ABT-199 had a strong combinatorial effect with nearly complete abolition of cell survival not only in WT-MYC cell line but also DHL (DOHH2) and THL (Val) DLBCL cell lines (Fig. 8a–c).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11696576

Cancers which rely on mitochondrial fatty acid oxidation (FAO) for energy derived from oxidative phosphorylation (OXPHOS) have a high oxidative burden.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC10873328

The cisplatin-resistant derivate ovarian cancer cell line A2780/CDDP was cultured in intermittent incremental exposure to cisplatin.

[ { "tags": [ "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cisplatin-resistant", "deriva...

PMC11694346

Upon reaction of BT-DNBS with biothiols, the N–S bond between the piperazine and DNBS is cleaved, which interrupts the PET process, resulting in the restoration of fluorescence.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10440586

Each column represents a sample in the TCGA dataset.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", "column", "represents", "a", "sample", "in", "the", "TCGA", "dataset", "." ] } ]

PMC9684669

To investigate the unique target of terfenadine in combinational chemotherapy for MDR cancer, the global gene expression of doxorubicin-sensitive and -resistant cell lines was profiled using RNA sequence.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11672881

These genes are involved in various processes, such as cellular stress response, transcription regulation, and reduces cell migration .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "genes", ...

PMC8524093

Released IFNs by infected cells exert an autocrine/paracrine signaling that will activate the Janus Kinase-signal transducer and activator of transcription (JAK-STAT) pathway, through binding to IFN-α/β receptors (IFNAR) (Majoros et al., 2017).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11707577

As shown in Figure 8A, treated polyps did not present signs of damage, at any time of continuous incubation, suggesting the biosafety of the engineered compound in absence of photostimulation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8469018

As the obtained tests results did not show any involvement of mitochondria in the toxicity of teriflunomide, the localization of the compound in individual cell compartments was examined, using chromatographic methods.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10998613

Taking into consideration the observation of CXCR4 homomultimerization and weak β2AR homodimerization, we conclude that the heteromeric clusters are composed of one β2AR and several CXCR4 receptors.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11306019

To investigate this further, we explored whether repeated treatments to maintain concentration over time are sufficient for BTZ to exhibit its anticancer effect at this level.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11706776

TPM transcripts per million.

[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "TPM", "transcripts", "per", "million", "." ] } ]

PMC11388384

To test whether diffusive populations reflected known features of SHH biochemistry, we took inspiration from prior experiments, in which SHH lacking its C-terminal cholesterol was found to form longer signaling gradients compared to wild-type SHH, presumably by altering SHH interactions in the extracellular space (22).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Aims: Here, we investigate whether BM Tfr2 targeting might represent a therapeutic option for TDT.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "Here", ",", "we", "investigate...

PMC10957991

Besides these physiological functions, TRPV4 seems to be important for the maintenance of epithelial integrity through its role in the regulation of on adherens and tight junction proteins.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9587866

Therefore, in our study we adopted the safer insilico approach which uses medicinal compounds to target EYA3 to obtain good cytotoxic inhibitor for EWS.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC11342785

We found that TPPP variants with strong MT-association triggered the strongest MT bundling activity when targeted to DDX4-droplet hubs (e.g. C-CORE) (Figs. 3C, 6F, S2B, and S9, A–C).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10919056

Transfection was performed using Lipofectamine 3000 (Invitrogen, Shanghai, China).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Transfection", "was", "performed", "using", "Lipofectamine", "3000", "(", "...

PMC10729469

After incubation, cells were centrifuged, resuspended in 4 mL 30% Percoll, layered with 4 mL HBSS, centrifuged (700xg for 10 min), and the cell pellet collected for flow staining.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10092581

Apart from the aforementioned behavior of Au(I) complexes, both Au(I) and Ag(I) complexes did not show any signs of degradation/decomposition in all the measured timepoints.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Transfusion dependence for 8 weeks was similar with 32.1% and 22.4% of the G group and 37.9% and 20.0% of the TC group being platelet transfusion or red blood cell transfusion independent, respectively.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11546117

The ESI voltage was 4 kV for all analytes.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "ESI", "voltage", "was", "4", "kV", "for", "all", "analytes", "." ] } ]

PMC11727062

To date, over 40 distinct ginsenosides have been identified (Xu et al. 2021).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "date", ",", "over", "40", "distinct", "gin...

PMC11708541

Nonetheless, a growing amount of data indicated that fampridine has offered benefits in addition to its symptomatic mechanism of action (Fig. 7).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC11739504

Fig. 5The acetyltransferase domain of Kat2b in the cytosol is significant for localization of IFT components at primary cilia. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "5The", "acetyltransf...

PMC10976516

Zugazagoitia et al.; Yang et al.; Wang et al.SurgeryMost cases of SCLC cannot be treated with surgery.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Zugazagoitia", "et", ...

PMC11604768

Consistent responses across the populations of barcodes suggested the induction of individual promoters following stimulation was highly reproducible.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Consistent", "responses", "across", "the", ...

PMC9577200

Moreover, we used the most efficient natural antibacterial material as an anticancer treatment.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "we", "used", "the", "most", "efficient", "natur...

PMC10154097

THE-2 and Huh7 cells were cultured in RMPI-1640, and BEL-7404, HCCLM3, and Hep3B were cultured in DMEM (Invitrogen, USA).

[ { "tags": [ "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", ...

PMC6181431

Many variants were discarded due to misaligned reads, repetitive sequence tracts, low quality base or read scores, or reads seen in only a single direction.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7802142

a Schematic illustration of ReN-NV preparation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "a", "Schematic", "illustration", "of", "ReN-NV", "preparation", "." ] } ]

PMC11593084

PODO/TERT256 and hTCEpi were purchased from EVERCYTE (Vienna, Austria).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PODO/TERT256", "and", "hTCEpi", "were", "purchased", "from", "EVERCYTE", "(", "V...

PMC8316344

Thereby, we tested whether TRIB2 regulates TFRC protein via PSMB5.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thereby", ",", "we", "tested", "whether", "TRIB2", "regulates", "TFRC", "protein", "v...

PMC11572213

Puromycin selection was applied for 3 days, and the medium was replaced.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Puromycin", "selection", "was", "applied", "for", "3", "days", ",", "...

PMC10936243

But I think in terms of management and cost, to wash it that often and to control with the bio-security, I think that will lead to higher cost” [D063].Participants reported using alternative forms of bedding such as disposable materials (e.g. newspapers).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC5839394

The emission-excitation (EEM) spectra of DNA were recorded by Luminescent Spectrometer (Perkin Elmer LS 55).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "emission-excitation", "(", ...

PMC11394730

Natural products also exhibit the ability to interfere with biosynthetic pathways critical for cancer cell survival.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Natural", "products", "also", "exhibit", "the", "abili...

PMC9592219

Finally, various binding modes were scored and sorted based on the molecular energy of docking, and the docking conformation of the molecule was determined based on the lowest docking energy.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10747160

When we look solely at the raw spike ELISA signal, it appears as though the M, N, and MNE strains have higher spike incorporation per virion when compared to Wild-Type virus (Figure S8A,C).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11281366

The resulting library was sequenced using a NovaSeq 6000 system (Illumina Technologies).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "resulting", "library", "was", "sequenced", "using", "a", ...

PMC11656657

Quantification of the specified cytokines, including CCL2, CCL3, CCL5, CCL7, CX3CL1, CXCL1, CXCL2, CXCL4, CXCL5, CXCL6, CXCL8 (IL8), CXCL13, CXCL14, G-CSF (CSF3), GM-CSF, IFN-gamma, IL10, IL13, IL1b, IL5, MCSF, and TNF-alpha, was normalized on blank control background for the in vitro data (in violet) and no tumor samp...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11055443

In addition to the anti-apoptotic effect of IL-6, previous studies have also shown that the MSCs soluble factors can lead to a decrease in apoptosis by reducing the activation of caspase 3 and 7 (39).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8097906

The bottom layer in each well of a 6-well plate (Sarstedt, Germany) was made with 1.5 ml of 1% agar (Sigma Aldrich, Saint Luis, USA) in assay medium and the top layer was made with 1.5 ml of 0.6% agar and 5000 cells in assay medium (i.e., 0.75 ml assay medium with 5000 cells and 0.75 ml 0.6% agarose solution).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11470381

Imaging sessions should be kept brief to prevent photo-bleaching of fluorescent proteins.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Imaging", "sessions", "should", "be", "kept", "brief", "to", "prevent", "photo-b...

PMC11588085

Bubble map of pathways enriched in patient samples with low XIST expression after GSEA.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Bubble", "map", "of", "pathways", "enriched", "in", "patient", "...

PMC8041314

As a first step, 93 reports between 2004 and 2021 were collected in which the evaluation of small-molecule inhibitors of ABCB1, ABCC1, and ABCG2 was described.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11592837

In drug-treated Jurkat cells, no substantial difference in the level of both Alu fragments was detected after 6 h, but then Alu fragments were observed at insignificantly higher levels compared to the control (Figure 5C,D).

[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11122631

With the in silico tool InflamNat, the predicted probabilities of the positive controls (aminoguanidine and apigenin) with IC50 (inhibition for NO production) <50 μM in macrophages were in a similar range (0.621–0.657), but most of the predicted probabilities of compounds were below 0.385 (Table S16).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11743414

Acute myeloid leukemia (AML) has a poor prognosis and high heterogeneity.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Acute", "myeloid", "leukemia", "(", "AML", ")", "has", "a", "poor", ...

PMC6892818

RCC lines ACHN, 786-O and A-704, and normal HRPT cells were treated with mCD40L for the indicated time periods (1.5, 3 and 6 h) and expression of TRAF1 (a), TRAF2 (b) and TRAF3 (c) was detected by immunoblotting (40 µg protein/lane) in controls (‘C’) vs. mCD40L-treated cells (‘mL’).

[ { "tags": [ "O", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC4112127

Approximately 60% of CCs are extrahepatic (ECC), arising from the region of the bifurcation of the right and left hepatic ducts extending distally to the distal common bile duct .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11750161

The signal sequence region was removed from eel LH/CGR and the fragments were inserted under the VSVG-tag signal sequence of the mammalian expression vector.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11576293

In addition, we investigated compounds with potential anticancer activities to see if they may act as dual inhibitors of EGFR and VEGFR-2 in order to get insight into their biological process.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11795610

All experiments were performed independently at least triplicate and the results were expressed as the mean ± standard deviation (SD).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "exper...

PMC9429973

After a median follow-up of 19 months (mo), 6 pts out of the 25 who reached CR/CRi (24%) relapsed and 20 out of 32 (63%) pts are alive.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11612315

The IC50 values for the calcium response of GLP-1, liraglutide, exendin-4, and exendin 9–39 were 178.60, 62.19, 64.49, and 28.18 nM, respectively (Fig. 5f–h).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11534035

Cells treated with 1 μM of G1 exhibited a non-significant reduction in size.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "treated", "with", "1", "μM", "of", "G1", "exhibited", "a", ...

PMC11694346

The detailed information of materials, reagents, instruments, synthesis, spectroscopic analysis, cell culture, cytotoxicity assay, fluorescence imaging experiments are provided in the ESI.† BT-Boc (100 mg, 0.11 mmol) was dissolved in dichloromethane (3 mL) in a dried flask.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC5417661

A four-parameter logistic fit of the area under the curve data between 96 and 186 h time point gave pIC50 values of 8.3 and 8.7 for NOV202 and Combretastatin A4, respectively (Figure 4D).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9621239

Besides, the plasmid expressing MYC-Flag was also co-transfected with the plasmids expressing HBx-WT (pcHBx-WT), HBx-SM (pcHBx-SM), HBx-DM (pcHBx-DM) or HBx-TM (pc-HBx-TM) into Huh 7 cells for 48 h. After lysis, MYC-Flag was immunoprecipitated by the Pierce Classic Magnetic IP/Co-IP Kit using the antibody (#14793, CST,...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC6163708

HH has been described to promote oncogenesis in leukemias , bladder cancer , and prostate cancer .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HH", "has", "been", "described", "to", "promote", ...

PMC11633763

The results of Western blot analysis and quantitative reverse transcription polymerase chain reaction (qRT‐PCR) showed that the expression of USP22 in osteosarcoma tissues was significantly higher than that in adjacent healthy tissues.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11753949

In both cases fixation was carried out for 20 min at room temperature.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "both", "cases", "fixation", "was", "carried", "out", "for", "20...

PMC9429973

All five Rac1 inhibitors resulted in an overall antiproliferative effect, tested at dosage around IC80.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "five", "Rac1", "inhibitors", "resulted", "in", ...

PMC11319300

This is supported by data derived from orangutans, which are thought not to encode MYEOV due to a mutation leading to a premature stop codon (Papamichos et al., 2015), yet they still have an enhancer/promoter chromatin state present in the same region (Figure 4).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11774112

The data in B are expressed as the means ± SDs (n= 6). (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "data", "in", "B", "are", "expressed", "as...

PMC11098378

Such IEPs might be useful molecular tools in identifying the conserved host immunity factors they target.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Such", "IEPs", "might", "be", "useful", "molecular", ...

PMC9220170

Therefore, to determine the effect of these selenium agents on the activity of mitochondrial reductases in living cells, which makes it possible to indirectly judge the change in their proliferative properties in the presence or absence of SELENOM-KD or SELENOT-KD, we performed an MTT analysis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9351137

To understand the relationships between Aurora B and the CRS under investigation, we asked whether the inhibition of its kinase activity affects the recruitment of both BAF53a and TIP60 to the midbody.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11787651

The new Sciex ZenoTOF 7600, with an increased scan speed and increased sensitivity enabled by the Zeno trap, has allowed us to decrease the mass spectrometer (or analytical) run time to only 20 min.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11539788

mTOR signalling is often activated by the upstream kinase AKT, resulting in the nuclear translocation of phosphorylated mTOR and ultimately activating downstream effectors such as S6K1 and 4EBP1 to regulate cell proliferation, survival, metabolism and autophagy .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8633974

Half of the collected cells were spun down and seeded in new plate and maintained in the incubator.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Half", "of", "the", "collected", "cell...