OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11532793	For a large-sample experiment with n = 100 samples per group, full performance was achieved with just B = 2 Gibbs samples per RNA sample, corresponding to N(B − 1) = 200 (Supplementary Figure S11).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11127909	It provides another strategy to inhibit mPTP opening.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "provides", "another", "strategy", "to", "inhibit", "mPTP", "opening", "." ] } ]
PMC9111184	For instance, EZ induced more noticeable changes on α-helices/Random Coil and β-stuctures than m-CA, RA and ChA when compared to the untreated cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC8540611	Hard" nanoparticles might accumulate more efficiently both in cells by uptake and at tumor sites due to enhanced permeability and retention (EPR) effect .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9412887	In conclusion, the above results demonstrated that the synergistic treatment therapy of SSB NMs and adoptive NK92 cells had a high efficacy in cancer treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11467800	Since no larvae with only K562‐IR cells were observed in the K562 enriched group, and similarly, no larvae with only K562 cells were observed in the K562‐IR enriched group, these data are not presented in Figure 2A,B, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O"...
PMC9429973	In Arm 3, JAKi-naïve MF pts are treated with pelabresib in combination with RUX.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "Arm", "3", ",", "JAKi-naïve", "MF", "pts", "are...
PMC10443665	It has been proved that members of the MDR efflux transporters such as MDR1 (P-GP), MRP1-5 (ABC1-5), and BCRP (ABCG2) are involved in MTX efflux.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11127909	However, there are few data showing that EFHD1 plays a role in tumor progression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "there", "are", "few", "data", "showing", ...
PMC11670954	Conversely, compared with that in the control + Y-27632 group, the concentration of FD-4 in the BA + Y-27632 group decreased.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Convers...
PMC11803918	The Laboratory Animal Unit of the University of Hong Kong distributed BALB/c nude mice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "The", "Laboratory", "Animal", "Unit", "of", "the", "Universit...
PMC11173119	One of the main pluripotency tests is the ability of cells to give rise to all three germ layers (ectoderm, mesoderm, and endoderm).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11389534	Notably, ODR4 plays an important role in the transport of newly synthesised adrenergic receptors (ARs).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notably", ",", "ODR4", "plays", "an", ...
PMC9429973	Overall, the reported findings allude to different maturation processes that likely contribute to shaping a distinct BcR IG signaling capacity in MBL, particularly LC-MBL, vs CLL.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11087301	Sorcin (soluble resistance-related calcium-binding protein) is a calcium-binding protein with many physiologic roles.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Sorcin", "(", "soluble", "resistance-related", "calcium-binding", ...
PMC9429973	The SID index date was defined as the first occurrence of a hypogammaglobulinemia ICD-10 code, or a record of low (<5.0 g/L) serum IgG levels.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11676670	SNP array genotyping analysis of the OVAR79 cell line revealed numerous chromosomal rearrangements.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SNP", "array", "genotyping", "analysis", "of", "the", "OVAR79", "c...
PMC9429973	However, AZA response does not require eradication of mutated HSCs and may be related to improved differentiation capacity of mutated hematopoietic stem and progenitor cells (HSPCs).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Statistical analysis was conducted using GraphPad Prism 9.1 (GraphPad Software Inc., USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "analysis", "was", "conducted", "using", "GraphPad"...
PMC11248911	The resulted “descriptors-target property” matrix was passed to RapidMiner Studio 9.3.001 for QSAR model construction.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "resulted", "“", "descriptors-target", "pro...
PMC11519567	The result of staining was observed with a fluorescence microscope system ZEISS, and the data were collected by the ImageJ software.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "resul...
PMC11772585	Some cells were analyzed using flow cytometry with EdU staining, while others were subjected to cellular immunofluorescence staining.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Some", "cells", "were", "analyzed...
PMC11754432	Gene expression analysis is relative to control siRNA and normalised to PPIA (A: N = 9, F: N = 4).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10411253	Secretion in the culture media was further determined by an enzyme linked immunosorbent assay (ELISA) specific to the C-terminal mature AMH, showing significantly reduced Arg312Cys and undetectable Glu389* AMH (Figure 1i).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11423992	CRL-8885, RRID: CVCL_3809).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CRL-8885", ",", "RRID", ":", "CVCL_3809", ")", "." ] } ]
PMC11792740	Therapeutic interventions aimed at restoring proper TCR signaling could potentially rejuvenate exhausted T cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therapeutic", "interventions", "aimed", "at", "restoring", "proper", "...
PMC6133382	The MGAT1 gene was PCR amplified using the primers F_CAGGCAAGCCAAAGGCAGCCTTG and R_CTCAGGGACTGCAGGCCTGTCTC (Eurofins Genomics, Louisville, KY, US) with Taq and dNTPs supplied by New England BioLabs (Ipswich, MA, US).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5810978	These results indicated that the 2-month cultured Caco-2 cells were more susceptible to the NoV strains tested.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "results", "indicated", "that", ...
PMC11739504	The black dotted line defines the area of the dilated tubule.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "black", "dotted", "line", "defines", "the", "area", "of", "the", "dilated", ...
PMC11756937	Cell lines were maintained and passaged until the cells had been expanded to a minimum of nine, preferably 12 wells of a six-well plate for the five-vial master bank (MB) freeze followed by five six-well plates for a 26-vial distribution bank (DB) freeze.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11612626	Lysates were centrifuged at 800 × g for 5 minutes, the supernatant collected, additional lysis buffer added and mixed, and the mixture centrifuged at 20,000 × g for 60 minutes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Methods: Methylation status of the genes in tumor tissue (n=73) was studied by methyl-specific PCR and methyl-sensitive analysis of high-resolution melting curves.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11185260	After treatment, cells were harvested, washed with cold PBS, and fixed with ice-cold 75% ethanol.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "treatment", ",", "cells"...
PMC11742047	To further investigate the ability of CBD to activate caspase activity in both HL-60 and K-562 cell lines, the caspase 3/7 activation was evaluated after 10 h in HL-60 cells and 18 h in K-562 cells, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11013014	M.p.	[ { "tags": [ "O", "O" ], "tokens": [ "M.p", "." ] } ]
PMC11588085	Additionally, the effect appears dependent on the cancer subtype, as luminal breast cancer shows no change in mesenchymal-like CSC (M-CSC) proportion (11).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11736898	Keloids are extremely challenging to treat, with low response rates to many current therapies and high recurrence rates after treatment .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Keloids", "are", ...
PMC11672881	These findings indicate that the combination significantly induced apoptosis compared to the control (Figure 3B), with notable rises in both early and late apoptotic cells, as determined by ANOVA (p < 0.01, n = 3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9436459	Finally, global acetyl deprotection of S175 and S181 delivered the desired dienes S176 and S182, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Finally", ",", "global", "acetyl", "de...
PMC7369657	However, such treatments have several deficiencies, such as cancer recurrence, incision infection, high expense, and side effects .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",...
PMC3122064	Surprisingly high levels of wild-type p53 have been frequently observed in TC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Surprisingly", "high", "levels", "of", "wild-type", "p53", "have", "been", "freq...
PMC11365427	Cell viability of MM cell lines after 48 h of phenylalanine deprivation. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "viability", "of", "MM", "cell", "lines", "after", "48", "h", ...
PMC11345828	The crude residue was purified by flash column chromatography eluting with 0 to 5% MeOH in DCM to afford 59 (1.6 g, 75% yield), LCMS Method 1: RT = 2.090 min, MS (ESI): m/z 550.9 (M + H).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11799978	For detection of CD140b expression, Brilliant Violet 650 Streptavidin (dilution 1:200, #405231, BioLegend) was introduced after the primary antibody incubation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC5415764	The LPN image was analyzed by a Tecnai G20 transmission electron microscope (TEM, FEI, Co., USA) at an operation voltage of 200 kV. To measure the encapsulation efficiency (EE) and loading efficiency (LE) of TET, the LPNs were dissolved in methanol to disrupt the polymeric shells before HPLC analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9454852	Currently, MPM incidence is significantly lower than that of new lung cancer cases, but it has gradually grown in the past five decades .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC7802142	Immunofluorescence staining for Ki67, a proliferation marker, was performed 6th day after the daily injection.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Immunofluorescence", "staining", "for", "Ki67", "...
PMC11388384	Given the drastic differences in diffusion rates between individual SHH molecules, we reasoned that each diffusing state likely reflected distinct interactions between SHH and the extracellular environment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8540692	Numerous factors implement the high aggressiveness of GBM cells, with the hyperactivated Wnt/β-catenin pathway being one of the most important.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Numerous", "factors", ...
PMC11489351	EIPA, 5-(N-ethyl-N-isopropyl) amiloride; FDR, false discovery rate; NH4Cl, ammonium chloride; pHi, intracellular pH. Next, we compared the RNA-Seq analysis in normal human epithelial cells to the prior microarray dataset obtained from NHE1-null (low pHi) and NHE1-competent (normal pHi) mouse fibroblasts (20).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11658074	The manifestations of photoaging observed in the skin of nude mice can serve as a model for the pathological changes observed in human ageing skin, with a substantially growing epidermis, thinning dermis, and more aged cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7612475	Cells were stained with S9.6 (Kerafast:ENH001; RRID:AB_2687463), and anti-nucleolin (Abcam:ab50279; RRID:AB_881762) primary antibodies and AlexaFluor 488/568 (Thermo Fisher Scientific) secondary antibodies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9581083	This formula can be considered as an adjunctive therapy for patients with COVID-19.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "formula", "can", "be", "considered", "as", "an", "adjunctive", ...
PMC11361748	Sections of WT mouse skin treated as shown in F were immunostained for K14, Ly6g, and nuclei (DAPI).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Section...
PMC11633763	Briefly, shNC‐143B and shUSP22‐143B cells (1 × 10 each) were subcutaneously transplanted into female nude mice (6‐week‐old).	[ { "tags": [ "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "...
PMC11155445	It was found that intramolecular hydrogen bonding present between N–H and the carbonyl group of acyl thiourea molecule was responsible for molecular structure.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	Overall response rate (ORR) was 68% after induction and 78% after reinduction.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Overall", "response", "rate", "(", "ORR", ")", "...
PMC10154881	Next, 12.5 μg protein was separated by SDS‐PAGE on 10% polyacrylamide gels and transferred to PVDF membranes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Next", ",", "12.5", "μg", "...
PMC11638255	Moreover, most survivors exhibit an increased risk of late mortality, secondary malignancies, and other chronic health conditions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "most", ...
PMC7987994	FBS represents the blood depleted of cells and coagulation factors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "FBS", "represents", "the", "blood", "depleted", "of", "cells", "and", "coagulation", "factors", ...
PMC9429973	All pts were Ph-negative.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "All", "pts", "were", "Ph-negative", "." ] } ]
PMC11750696	Moreover, increased CHOP levels were identified within CD8 TILs in ovarian cancer, which was linked to the activation of the PERK signaling axis and the promotion of ATF4, consequently suppressing T-bet expression (60).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9910796	For alkaline carbonate extraction, membrane fractions were treated with 0.1 M Na2CO3 pH 11.5, for 30 min at 4°C and centrifuged for 10 min at 16,000 x g. Both supernatant and sediment were dissociated with electrophoresis sample buffer (2% SDS, 100 mM DTT, 125 mM Tris-HCl, pH 6.8).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11591038	Another study also reported that the glycolysis metabolism induced by HIF-1 is crucial for M1 macrophage polarization in mice .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Another", "study", "also", "repor...
PMC9429973	Sensitivity analyses included additional covariates: high-risk cytogenetics and extramedullary disease.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Sensitivity", "analyses", "included", "additional", "covariates", ":", "high-risk", "cytogenetics...
PMC6222726	Toledo further divided section Bursera into three groups that can be distinguished by the color of the exfoliating bark: mulatos, red cuajiotes, and yellow cuajiotes .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Pirtobrutinib was well tolerated and exhibited a wide therapeutic index.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Pirtobrutinib", "was", "well", "tolerated", "and", "exhibited", "a", "wide", "therapeutic", "ind...
PMC9429973	Results: PKR activity was increased compared to vehicle (DMSO) to a similar extent in the presence of mitapivat or AG-946 (Figure 1A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11352666	Additionally, combined treatment with MRX-2843 and the BCL-2 inhibitor venetoclax provided significantly enhanced therapeutic efficacy compared to MRX-2843 and/or venetoclax in both cell lines (Figure 6A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7229095	Finally, candidate cell lines were identified after single cell isolation by limited dilution cloning (LDC) and analysis of single clones using an Octet QKe in 96-well and 6-well plates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9444294	HSSYII and SYO-1 cells were grown to confluence in 15 cm dishes.	[ { "tags": [ "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HSSYII", "and", "SYO-1", "cells", "were", "grown", "to", "confluence...
PMC11746942	The database search results were filtered and exported with a < 1% false discovery rate (FDR) at the peptide and protein levels.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11297139	Recent studies have highlighted the importance of phase separation in various biological processes (BPs), such as RNA processing, autophagy, and cell signaling.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11476837	Experiments were performed with three schemes of cell treatment: HL-60 and HL-60/DR cells were incubated with doxorubicin for 24 h (schemes 1 and 2, respectively); and HL-60/DR cells were pre-incubated with NRF2 inhibitors for 24 h followed by the incubation with doxorubicin for 24 h (scheme 3) (Figure 9).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10490530	Increased transcript expression of both NFκBIA and hLuz in incremental TNFα-treated conditions confirmed that hLuz expression is governed by NF-κB binding ability at the response element site provided.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11727306	To these wells were added an additional 25 µL aliquot of Raji cells at a concentration 2 × 10 cells per mL. Finally, a 25 µL aliquot of SEA, SED, SEE or SPE-C solution was added to each well to achieve the desired final concentration of toxin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11496728	The Apaf1 gene was designed using an online design website (crispor.tefor.net) and labeled as sgRNA1 (CACCGTGGAAGGCCACTATGAAGA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "Apaf1", "gene", ...
PMC11638255	One independent experiment.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "One", "independent", "experiment", "." ] } ]
PMC10957991	Stem/progenitor cell marker, CK5, was detected with IF stainings from ctrl MCF10A and TRPV4-depleted MCF10A cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "Stem/progenitor", "cell", ...
PMC10452486	Most importantly, they may serve as ligands for different polypeptides and proteins, which include insulin receptors and T cell receptor (α/β) molecules as well as KIR and Leukocyte Ig-like families, expressed on NK cells, different subsets of T cells, and other immune cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10490530	Further, by delivering one million A549-hLuz or A549-Luz cells via tail-vein in two sets of mice, potential improvement as a BLI reporter for deep tissue imaging ability was judged.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC9444294	A Immunofluorescence images of SS18-SSX.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "Immunofluorescence", "images", "of", "SS18-SSX", "." ] } ]
PMC10788478	LGR6 expression levels were evaluated in NSCLC tumors using the TCGA dataset.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "LGR6", "expression", "levels", "were", "evaluated", "in", "NSCLC", "tumors", "us...
PMC11700340	Comparison of Linagliptin and Vincristine Growth Inhibition at 72 hours.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Comparison", "of", "Linagliptin", "and", "Vincristine", "Growth", "Inhibition", "at", "72", "hou...
PMC11438317	Cells were washed twice with PBS between the different steps.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "washed", "twice", "with", "PBS", "between", "the", "different", "steps", ...
PMC10778532	Graphics and statistical analyses were performed with GraphPad Prism software version 9.00 (GraphPad Software, La Jolla, CA, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Graphic...
PMC9429973	Results: Flumatinib and ABT-199 were sensitive to SUP-B15 in both single or combined treatment in a dose-dependent manner (Fig. 1A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC6892818	Cell death was detected 48 h later using the CytoTox-Glo assay (see Methods).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "death", "was", "detected", "48", "h", "later", ...
PMC11754291	The y-axis indicates the fold change in cell viability relative to sham control (untreated cells). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "y-axis", "indicates", "the", "f...
PMC9813422	The MCPyV genome is maintained as a replication-competent episome in persistently infected cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "MCPyV", "genome", "is", "maintained", "as", "a", "replication-compet...
PMC9878278	ZIKV titers in cell culture supernatants at different time points after infection were analyzed by plaque assay using Vero cells and expressed as ZIKV PFU per mL of supernatant (Siemann et al., 2017).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", ...
PMC11363012	Finally, we examined flower petals, which contain flavonoids, anthocyanins, iridoids, and alkaloids.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Finally", ",", "we", "examined", "flower", ...
PMC9812014	Emetine, an ipecac alkaloid, has significant anti-HIV properties.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Emetine", ",", "an", "ipecac", "alkaloid", ",", "has", "significant", "anti-HIV", "properties", ...
PMC9429973	Detailed data analysis and progress in answering the initial 3 themes is ongoing.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Detailed", "data", "analysis", "and", "progress", "in", "answering", "the",...
PMC5916734	A congenital absence of this gene or a low level of functionally active factor IX cause hemophilia B, the X-linked recessive genetic disorder that occurs in approximately one out of 30,000 males.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11740907	The HeLa cell line (1×10) underwent to a 24-hour exposure with pure P5W30 (IC90 = 30.87 µg/mL) and P5W30-BW-SLNs (IC90 = 14.72 µg/mL).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	As 2,3-DPG affects the oxygen affinity of Hb, all measurements were correlated to p50.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "2,3-DPG", "affects", "the", "oxygen", "affinity", "of...
PMC11680982	Contextually, parallel insights emerged from the realm of anti-HER2 monoclonal antibodies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Contextually", ",", "parallel", "insights", "emerged", "from", "the", "realm", "...
PMC11774747	Non-transduced (NT) EBVST and CD30.CAR-EBVST were eliminated while CD30.CAR-EBVST persisted, expanded and prevented p-ART expansion.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Non-transduced", "(", "NT", ")", "EBVS...
PMC9429973	In addition, it appears to be potentially involved in the onset of resistance to the BTK inhibitor Ibrutinib, thus providing an alternative mechanism that may explain drug failure in the resistant patients who do not carry BTK/PLCG2 mutations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11532793

For a large-sample experiment with n = 100 samples per group, full performance was achieved with just B = 2 Gibbs samples per RNA sample, corresponding to N(B − 1) = 200 (Supplementary Figure S11).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11127909

It provides another strategy to inhibit mPTP opening.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "provides", "another", "strategy", "to", "inhibit", "mPTP", "opening", "." ] } ]

PMC9111184

For instance, EZ induced more noticeable changes on α-helices/Random Coil and β-stuctures than m-CA, RA and ChA when compared to the untreated cells.

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PMC8540611

Hard" nanoparticles might accumulate more efficiently both in cells by uptake and at tumor sites due to enhanced permeability and retention (EPR) effect .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC9412887

In conclusion, the above results demonstrated that the synergistic treatment therapy of SSB NMs and adoptive NK92 cells had a high efficacy in cancer treatment.

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PMC11467800

Since no larvae with only K562‐IR cells were observed in the K562 enriched group, and similarly, no larvae with only K562 cells were observed in the K562‐IR enriched group, these data are not presented in Figure 2A,B, respectively.

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PMC9429973

In Arm 3, JAKi-naïve MF pts are treated with pelabresib in combination with RUX.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "Arm", "3", ",", "JAKi-naïve", "MF", "pts", "are...

PMC10443665

It has been proved that members of the MDR efflux transporters such as MDR1 (P-GP), MRP1-5 (ABC1-5), and BCRP (ABCG2) are involved in MTX efflux.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11127909

However, there are few data showing that EFHD1 plays a role in tumor progression.

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PMC11670954

Conversely, compared with that in the control + Y-27632 group, the concentration of FD-4 in the BA + Y-27632 group decreased.

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PMC11803918

The Laboratory Animal Unit of the University of Hong Kong distributed BALB/c nude mice.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "The", "Laboratory", "Animal", "Unit", "of", "the", "Universit...

PMC11173119

One of the main pluripotency tests is the ability of cells to give rise to all three germ layers (ectoderm, mesoderm, and endoderm).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11389534

Notably, ODR4 plays an important role in the transport of newly synthesised adrenergic receptors (ARs).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notably", ",", "ODR4", "plays", "an", ...

PMC9429973

Overall, the reported findings allude to different maturation processes that likely contribute to shaping a distinct BcR IG signaling capacity in MBL, particularly LC-MBL, vs CLL.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11087301

Sorcin (soluble resistance-related calcium-binding protein) is a calcium-binding protein with many physiologic roles.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Sorcin", "(", "soluble", "resistance-related", "calcium-binding", ...

PMC9429973

The SID index date was defined as the first occurrence of a hypogammaglobulinemia ICD-10 code, or a record of low (<5.0 g/L) serum IgG levels.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11676670

SNP array genotyping analysis of the OVAR79 cell line revealed numerous chromosomal rearrangements.

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PMC9429973

However, AZA response does not require eradication of mutated HSCs and may be related to improved differentiation capacity of mutated hematopoietic stem and progenitor cells (HSPCs).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Statistical analysis was conducted using GraphPad Prism 9.1 (GraphPad Software Inc., USA).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "analysis", "was", "conducted", "using", "GraphPad"...

PMC11248911

The resulted “descriptors-target property” matrix was passed to RapidMiner Studio 9.3.001 for QSAR model construction.

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PMC11519567

The result of staining was observed with a fluorescence microscope system ZEISS, and the data were collected by the ImageJ software.

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PMC11772585

Some cells were analyzed using flow cytometry with EdU staining, while others were subjected to cellular immunofluorescence staining.

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PMC11754432

Gene expression analysis is relative to control siRNA and normalised to PPIA (A: N = 9, F: N = 4).

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PMC10411253

Secretion in the culture media was further determined by an enzyme linked immunosorbent assay (ELISA) specific to the C-terminal mature AMH, showing significantly reduced Arg312Cys and undetectable Glu389* AMH (Figure 1i).

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PMC11423992

CRL-8885, RRID: CVCL_3809).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CRL-8885", ",", "RRID", ":", "CVCL_3809", ")", "." ] } ]

PMC11792740

Therapeutic interventions aimed at restoring proper TCR signaling could potentially rejuvenate exhausted T cells.

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PMC6133382

The MGAT1 gene was PCR amplified using the primers F_CAGGCAAGCCAAAGGCAGCCTTG and R_CTCAGGGACTGCAGGCCTGTCTC (Eurofins Genomics, Louisville, KY, US) with Taq and dNTPs supplied by New England BioLabs (Ipswich, MA, US).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC5810978

These results indicated that the 2-month cultured Caco-2 cells were more susceptible to the NoV strains tested.

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PMC11739504

The black dotted line defines the area of the dilated tubule.

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PMC11756937

Cell lines were maintained and passaged until the cells had been expanded to a minimum of nine, preferably 12 wells of a six-well plate for the five-vial master bank (MB) freeze followed by five six-well plates for a 26-vial distribution bank (DB) freeze.

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PMC11612626

Lysates were centrifuged at 800 × g for 5 minutes, the supernatant collected, additional lysis buffer added and mixed, and the mixture centrifuged at 20,000 × g for 60 minutes.

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PMC9429973

Methods: Methylation status of the genes in tumor tissue (n=73) was studied by methyl-specific PCR and methyl-sensitive analysis of high-resolution melting curves.

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PMC11185260

After treatment, cells were harvested, washed with cold PBS, and fixed with ice-cold 75% ethanol.

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PMC11742047

To further investigate the ability of CBD to activate caspase activity in both HL-60 and K-562 cell lines, the caspase 3/7 activation was evaluated after 10 h in HL-60 cells and 18 h in K-562 cells, respectively.

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PMC11013014

M.p.

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PMC11588085

Additionally, the effect appears dependent on the cancer subtype, as luminal breast cancer shows no change in mesenchymal-like CSC (M-CSC) proportion (11).

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PMC11736898

Keloids are extremely challenging to treat, with low response rates to many current therapies and high recurrence rates after treatment .

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PMC11672881

These findings indicate that the combination significantly induced apoptosis compared to the control (Figure 3B), with notable rises in both early and late apoptotic cells, as determined by ANOVA (p < 0.01, n = 3).

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PMC9436459

Finally, global acetyl deprotection of S175 and S181 delivered the desired dienes S176 and S182, respectively.

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PMC7369657

However, such treatments have several deficiencies, such as cancer recurrence, incision infection, high expense, and side effects .

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PMC3122064

Surprisingly high levels of wild-type p53 have been frequently observed in TC.

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PMC11365427

Cell viability of MM cell lines after 48 h of phenylalanine deprivation. (

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PMC11345828

The crude residue was purified by flash column chromatography eluting with 0 to 5% MeOH in DCM to afford 59 (1.6 g, 75% yield), LCMS Method 1: RT = 2.090 min, MS (ESI): m/z 550.9 (M + H).

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PMC11799978

For detection of CD140b expression, Brilliant Violet 650 Streptavidin (dilution 1:200, #405231, BioLegend) was introduced after the primary antibody incubation.

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PMC5415764

The LPN image was analyzed by a Tecnai G20 transmission electron microscope (TEM, FEI, Co., USA) at an operation voltage of 200 kV. To measure the encapsulation efficiency (EE) and loading efficiency (LE) of TET, the LPNs were dissolved in methanol to disrupt the polymeric shells before HPLC analysis.

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PMC9454852

Currently, MPM incidence is significantly lower than that of new lung cancer cases, but it has gradually grown in the past five decades .

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PMC7802142

Immunofluorescence staining for Ki67, a proliferation marker, was performed 6th day after the daily injection.

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PMC11388384

Given the drastic differences in diffusion rates between individual SHH molecules, we reasoned that each diffusing state likely reflected distinct interactions between SHH and the extracellular environment.

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PMC8540692

Numerous factors implement the high aggressiveness of GBM cells, with the hyperactivated Wnt/β-catenin pathway being one of the most important.

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PMC11489351

EIPA, 5-(N-ethyl-N-isopropyl) amiloride; FDR, false discovery rate; NH4Cl, ammonium chloride; pHi, intracellular pH. Next, we compared the RNA-Seq analysis in normal human epithelial cells to the prior microarray dataset obtained from NHE1-null (low pHi) and NHE1-competent (normal pHi) mouse fibroblasts (20).

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PMC11658074

The manifestations of photoaging observed in the skin of nude mice can serve as a model for the pathological changes observed in human ageing skin, with a substantially growing epidermis, thinning dermis, and more aged cells .

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PMC7612475

Cells were stained with S9.6 (Kerafast:ENH001; RRID:AB_2687463), and anti-nucleolin (Abcam:ab50279; RRID:AB_881762) primary antibodies and AlexaFluor 488/568 (Thermo Fisher Scientific) secondary antibodies.

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PMC9581083

This formula can be considered as an adjunctive therapy for patients with COVID-19.

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PMC11361748

Sections of WT mouse skin treated as shown in F were immunostained for K14, Ly6g, and nuclei (DAPI).

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PMC11633763

Briefly, shNC‐143B and shUSP22‐143B cells (1 × 10 each) were subcutaneously transplanted into female nude mice (6‐week‐old).

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PMC11155445

It was found that intramolecular hydrogen bonding present between N–H and the carbonyl group of acyl thiourea molecule was responsible for molecular structure.

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PMC9429973

Overall response rate (ORR) was 68% after induction and 78% after reinduction.

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PMC10154881

Next, 12.5 μg protein was separated by SDS‐PAGE on 10% polyacrylamide gels and transferred to PVDF membranes.

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PMC11638255

Moreover, most survivors exhibit an increased risk of late mortality, secondary malignancies, and other chronic health conditions.

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PMC7987994

FBS represents the blood depleted of cells and coagulation factors.

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PMC9429973

All pts were Ph-negative.

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PMC11750696

Moreover, increased CHOP levels were identified within CD8 TILs in ovarian cancer, which was linked to the activation of the PERK signaling axis and the promotion of ATF4, consequently suppressing T-bet expression (60).

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PMC9910796

For alkaline carbonate extraction, membrane fractions were treated with 0.1 M Na2CO3 pH 11.5, for 30 min at 4°C and centrifuged for 10 min at 16,000 x g. Both supernatant and sediment were dissociated with electrophoresis sample buffer (2% SDS, 100 mM DTT, 125 mM Tris-HCl, pH 6.8).

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PMC11591038

Another study also reported that the glycolysis metabolism induced by HIF-1 is crucial for M1 macrophage polarization in mice .

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PMC9429973

Sensitivity analyses included additional covariates: high-risk cytogenetics and extramedullary disease.

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PMC6222726

Toledo further divided section Bursera into three groups that can be distinguished by the color of the exfoliating bark: mulatos, red cuajiotes, and yellow cuajiotes .

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PMC9429973

Pirtobrutinib was well tolerated and exhibited a wide therapeutic index.

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PMC9429973

Results: PKR activity was increased compared to vehicle (DMSO) to a similar extent in the presence of mitapivat or AG-946 (Figure 1A).

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PMC11352666

Additionally, combined treatment with MRX-2843 and the BCL-2 inhibitor venetoclax provided significantly enhanced therapeutic efficacy compared to MRX-2843 and/or venetoclax in both cell lines (Figure 6A).

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PMC7229095

Finally, candidate cell lines were identified after single cell isolation by limited dilution cloning (LDC) and analysis of single clones using an Octet QKe in 96-well and 6-well plates.

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PMC9444294

HSSYII and SYO-1 cells were grown to confluence in 15 cm dishes.

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PMC11746942

The database search results were filtered and exported with a < 1% false discovery rate (FDR) at the peptide and protein levels.

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PMC11297139

Recent studies have highlighted the importance of phase separation in various biological processes (BPs), such as RNA processing, autophagy, and cell signaling.

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PMC11476837

Experiments were performed with three schemes of cell treatment: HL-60 and HL-60/DR cells were incubated with doxorubicin for 24 h (schemes 1 and 2, respectively); and HL-60/DR cells were pre-incubated with NRF2 inhibitors for 24 h followed by the incubation with doxorubicin for 24 h (scheme 3) (Figure 9).

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PMC10490530

Increased transcript expression of both NFκBIA and hLuz in incremental TNFα-treated conditions confirmed that hLuz expression is governed by NF-κB binding ability at the response element site provided.

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PMC11727306

To these wells were added an additional 25 µL aliquot of Raji cells at a concentration 2 × 10 cells per mL. Finally, a 25 µL aliquot of SEA, SED, SEE or SPE-C solution was added to each well to achieve the desired final concentration of toxin.

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PMC11496728

The Apaf1 gene was designed using an online design website (crispor.tefor.net) and labeled as sgRNA1 (CACCGTGGAAGGCCACTATGAAGA).

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PMC11638255

One independent experiment.

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PMC10957991

Stem/progenitor cell marker, CK5, was detected with IF stainings from ctrl MCF10A and TRPV4-depleted MCF10A cell lines.

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PMC10452486

Most importantly, they may serve as ligands for different polypeptides and proteins, which include insulin receptors and T cell receptor (α/β) molecules as well as KIR and Leukocyte Ig-like families, expressed on NK cells, different subsets of T cells, and other immune cells.

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PMC10490530

Further, by delivering one million A549-hLuz or A549-Luz cells via tail-vein in two sets of mice, potential improvement as a BLI reporter for deep tissue imaging ability was judged.

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PMC9444294

A Immunofluorescence images of SS18-SSX.

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PMC10788478

LGR6 expression levels were evaluated in NSCLC tumors using the TCGA dataset.

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PMC11700340

Comparison of Linagliptin and Vincristine Growth Inhibition at 72 hours.

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PMC11438317

Cells were washed twice with PBS between the different steps.

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PMC10778532

Graphics and statistical analyses were performed with GraphPad Prism software version 9.00 (GraphPad Software, La Jolla, CA, USA).

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PMC9429973

Results: Flumatinib and ABT-199 were sensitive to SUP-B15 in both single or combined treatment in a dose-dependent manner (Fig. 1A).

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PMC6892818

Cell death was detected 48 h later using the CytoTox-Glo assay (see Methods).

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PMC11754291

The y-axis indicates the fold change in cell viability relative to sham control (untreated cells). (

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PMC9813422

The MCPyV genome is maintained as a replication-competent episome in persistently infected cells.

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PMC9878278

ZIKV titers in cell culture supernatants at different time points after infection were analyzed by plaque assay using Vero cells and expressed as ZIKV PFU per mL of supernatant (Siemann et al., 2017).

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PMC11363012

Finally, we examined flower petals, which contain flavonoids, anthocyanins, iridoids, and alkaloids.

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PMC9812014

Emetine, an ipecac alkaloid, has significant anti-HIV properties.

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PMC9429973

Detailed data analysis and progress in answering the initial 3 themes is ongoing.

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PMC5916734

A congenital absence of this gene or a low level of functionally active factor IX cause hemophilia B, the X-linked recessive genetic disorder that occurs in approximately one out of 30,000 males.

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PMC11740907

The HeLa cell line (1×10) underwent to a 24-hour exposure with pure P5W30 (IC90 = 30.87 µg/mL) and P5W30-BW-SLNs (IC90 = 14.72 µg/mL).

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PMC9429973

As 2,3-DPG affects the oxygen affinity of Hb, all measurements were correlated to p50.

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PMC11680982

Contextually, parallel insights emerged from the realm of anti-HER2 monoclonal antibodies.

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PMC11774747

Non-transduced (NT) EBVST and CD30.CAR-EBVST were eliminated while CD30.CAR-EBVST persisted, expanded and prevented p-ART expansion.

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PMC9429973

In addition, it appears to be potentially involved in the onset of resistance to the BTK inhibitor Ibrutinib, thus providing an alternative mechanism that may explain drug failure in the resistant patients who do not carry BTK/PLCG2 mutations.

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