Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
 Community
1
PMCID
string
Sentences
string
ner
list
PMC11714165
Micro‐CT reconstruction of the tumor‐bearing tibias from mice after therapy in different treatment groups.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Micro‐CT", "reconstruction", "of", "the", "tumor‐bearing", "tibias", "...
PMC11791264
E, SKOV3 cells stably expressing pCDH or SETD7 were transfected with GFP-LC3B WT or K51M mutant in the absence or presence of Baf A1 (100 nM) for 10 h. Top panels show the representative images of LC3B puncta, and the bottom panels show the quantification of LC3B puncta.
[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11277157
In cancer cells, DJ-1 regulates the JNK pathway and consequently impacts autophagy .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "cancer", "cells", ",", "DJ-1", "regulates", "the", "JNK", "path...
PMC2193049
Digestion of synthetic peptides extended at the NH2 or COOH terminus of MAGE-3271–279 with purified human proteasome revealed that the generation of the COOH terminus of the antigenic peptide was impaired.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Eighty percent had bone marrow (BM) involvement and the majority were categorized as ISS/R-ISS II.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Eighty", "percent", "had", "bone", "marrow", ...
PMC9429973
For each 28-day cycle, aza is administered subcutaneously or intravenously (IV) daily for 7 days within the first 9 days (7-0-0 or 5-2-2 schedule); ven is administered orally daily on days 1–28 (AML, following dose ramp-up) or days 1–14 (ven-containing MDS cohorts).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5261804
By measuring the essentiality of every gene (node) in a network, and understanding how proteins are connected through protein interactions (edges), we aim to estimate the essentiality of individual PPIs that are silenced in aggregate as a gene is knocked down by shRNA.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Image: Summary/Conclusion: Both single drugs of flumatinib and ABT-199 are sensitive to SUP-B15 human Ph+ B-cell ALL cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Image", ":", "Summa...
PMC11190538
Natural, conveniently available, and cost-effective antiviral drugs that can be mass-produced in a short time are desperately needed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Natural", ",", "conveniently...
PMC10810426
Next, to determine where early reverse transcription was occurring, we infected DCs and at 4 hpi, carried out fractionation followed by pulldown with S9.6 antibody and analysis of the bound nucleic acid.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10898159
The pathogenesis of GIST involve gain-of-function mutation in KIT (accounts for 75–80%), platelet-derived growth factor receptorα(PGFRA) (< 10%), or gene abnormalities including succinate dehydrogenase (SDH)-deficiency, the mutations of neurofibromin 1 (NF1), Kirsten rat sarcoma viral oncogene homolog (KRAS) and Harvey...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9479186
Then, the plates were measured at a wavelength of 490/570 nm.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", "the", "plates", "were", "measured", "at", "a", "wavelength", ...
PMC11271278
Two separate sgRNAs were used for each condition (sgNT1/sgNT2, sgMYC-prom#1/ sgMYC-prom#2).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Two", "separate", "sgRNAs", "were", "used", "for", "each", "cond...
PMC11055510
This study was approved by the Medical Ethics Committee of Hainan Women and Children’s Hospital (Approval No: 2021-030).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11774747
The report by Omer et al. is currently the only study that compares CD28 and 41BB signals in CAR-VSTs (86).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "repor...
PMC6600592
Cyclohexyl (E)-4-methoxyimino-4-phenylbutanoate (4A-2).
[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cyclohexyl", "(E)-4-methoxyimino-4-phenylbutanoate", "(", "4A-2", ")", "." ] } ]
PMC11721295
Differences in ligands and receptors between groups were determined using Wilcoxon’s rank-sum test, and P values were adjusted for multiple comparisons using Bonferroni’s correction method.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11687167
Momtazi-Borojeni et al. produced specific antibodies against PCSK9 in C57BL/6 mice treated with nanoliposomal PCSK9 vaccines.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Momtazi-Borojeni", "et", "al.", "produced", "specif...
PMC11766332
Serum glycome analyses of patients with ADHD have revealed recurrent modifications such as increased antennary fucosylation and decreased levels of some complex glycans with three or four antennas .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11106977
Further studies are needed to elucidate these mechanisms.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Further", "studies", "are", "needed", "to", "elucidate", "these", "mechanisms", "." ] } ]
PMC10988555
Then, fresh aqua regia was added to the supernatant tube and to the cellular fractions and incubated overnight at room temperature (RT) in the hood fume.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11612508
Chitosan (CS) was used to prepare microspheres.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Chitosan", "(", "CS", ")", "was", "used", "to", "prepare", "microspheres", "." ] } ]
PMC11310713
The GTB-injected rats reduced the increasing rates 2 weeks after injecting GTBs, which recovered similar levels to ovary-intact rats.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "GTB-injected", "rats"...
PMC11578343
ω is modulated by controlling each zone's period length, L p. For the experiments described here, we employed a w contraction corresponding to an approximate strain of 𝜀 = 0.4 + 0.15cos(ωt).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9275501
Tumor immunotherapy can achieve the purpose of identifying and killing tumor cells by regulating the immune ability of patients, and minimize the toxicity (Zhang et al., 2016c).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11087055
Flowtrace visualized the trajectories of the cell flow, whereas the streamlines illustrated the averaged flow pattern in the time period.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Flowtrace", "visualized...
PMC6450504
p < .05, ***p < .0005, ****p < .0001, two-way ANOVA with Tukey’s multiple comparisons test. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11519567
The state of the condensates was observed under an inverted fluorescence microscope.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "state", "of", "the", "condensates", "was", "observed", "under", "an", ...
PMC11514418
In conclusion, the combined therapy of APS and GS can improve short-term efficacy and long-term survival in the treatment of pancreatic cancer.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC11629192
If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10932641
NC, negative control; lncRNA, long noncoding RNA; SI, silent; OE, overexpressive.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "NC", ",", "negative", "control", ";", ...
PMC11686380
Total length was calculated for apical and basal dendrites.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Total", "length", "was", "calculated", "for", "apical", "and", "basal", "dendrites", "." ] } ]
PMC11357960
This seemed to be related to the similar decreased degree of different lymphocyte subsets induced by dysregulated SUMOylation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "seemed", "to", "be", "related"...
PMC11519077
Finally, the flask with the cell was placed in an incubator at 37°C, 5% CO2, and 95% humidity .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC6160470
indicate that tested crown ether compounds inhibit viability of both cell lines.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "indicate", "that", "tested", "crown", "ether", "compounds", "inhibit", "viability", ...
PMC8389560
It is known that selenium-containing compounds have shown high efficiency as anticancer drugs, and one of the key mechanisms in this case is the induction of apoptosis .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9895440
d, i-k Statistics are paired 2-way ANOVA with Holm-Sidak correction. *
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "d", ",", "i-k", "Statistics", "are", "paired", "2-way", "ANOVA", "with", "...
PMC11721277
Increasing the incubation temperature to 85 °C for 15 min significantly (p < 0.05) improved the RCY from 66.0 ± 0.7% to 82.3 ± 0.3%.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11188874
In contrast, the chimeric antigen receptor (CAR) T-cell approach is generally limited to targeting membrane-bound proteins.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "contrast", ",", "the", ...
PMC8633974
Defining the optimal gRNAs to eliminate HIV-1 infection and implementing the approach towards human trials is a challenge.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Defining", "the", "optimal", "gRNAs", ...
PMC9429973
We selected patients that had obtained a complete (CR) or partial response (PR) after induction therapy regardless of follow-up with RTX maintenance.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11489175
The discovery of new chemical entities capable of inhibiting DUBs is being pursued through innovative strategies that go beyond target-based screen, instead proposing target-class approach to DUB inhibitor development 125, 126.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10788478
Three or more independent groups were compared using the Kruskal–Wallis test with Dunn's multiple comparisons, or one‐way analysis of variance with Bonferroni's multiple comparisons.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Two months later, she was readmitted due to suspected sepsis abdominal.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Two", "months", "later", ",", "she", "was", "readmitted", "due", "to", "su...
PMC11635087
Chloroplast in a subcellular vesicle reveals the expansion of the space between thylakoid membranes. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Chloroplast", "in", "a", "subcellular", "vesicle", "reveals", ...
PMC11566417
This has been shown previously in both murine and human cells, where it was found that hTERT did not cause chromosomal rearrangements over multiple subcultures [121, 123–125].
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11768927
To investigate the impact of ICI treatment on the efficacy of oncolytic VSV therapy, Cockle et al. evaluated the effects of two ICIs, anti-PD-1 and anti-CTLA-4 antibodies, in a murine glioblastoma model.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11419566
In their results, the expressions of P-gp and caveolin-1 were decreased, and MDR was reversed after PT-mediated.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "their", "results", ",", ...
PMC11490153
For this reason, it significantly (P < 0.05) showed the best efficacy with an IC50 of 27 (19–39) µg/mL under normoxic and hypoxic conditions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11743975
As we previously demonstrated, blue light illumination rapidly induces the formation of mCherry-CRY2 protein clusters in the cytosol, and the dimerization of CRY2 and CIBN further promotes mitochondrial aggregation (Figure 3A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10178190
Solvent-treated samples were incubated with 0.1% (w/v) dimethyl sulfoxide.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Solvent-treated", "samples", "were", "incubated", "with", "0.1", "%", "(", "w/v"...
PMC10656496
Serial assessments of resection specimens, paired relapse specimens and ctDNA will hopefully improve on our ability to address subclinical populations of osteosarcoma which often determine the ultimate outcome.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10870498
After the cell confluence reached 80%, transfection was performed using Lipofectamine 2000 (Invitrogen) according to the manufacturer’s instructions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After",...
PMC10523483
Representative fluorescent images (Left) and quantification (Right) of DHE staining of K (n = 12) and KH (n = 6) lung tumors. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10747160
The transfected cells were returned to the incubator for an additional 48 h to allow for pseudoviral production.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "transfected", "cells", "were", ...
PMC9541067
p < 0.001) RT-qPCR and western blotting validation of the expression level of SUCLG1, PCK2, GLDC in OSRC-2 and A498 cell lines.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "...
PMC3019555
cDNA was synthesized using the MicroRNA Reverse Transcription kit (TaqMan), and qRT-PCR was performed using miRNA (TaqMan).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "cDNA", "was"...
PMC11750712
Cells were washed and resuspended in a secondary only master mix containing Streptavidin antibody BV421 (405225, BioLegend).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "washed", ...
PMC9429973
Previous work in mouse models and primary human cells suggested impaired function of abundantly expressed GATA1 protein in AEL cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Previous", "work", "in", ...
PMC8873393
C Biotype distribution of all the transcripts identified by RNA-seq analysis generated from cytoplasm or chromatin fractions annotated relatively to human hg38.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "C", "Biotype...
PMC9031474
In a previous study, it was shown that 2-alkenals lead to DNA damage in V79 lung fibroblasts and Caco-2 colorectal carcinoma cells .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens"...
PMC11095939
Real-time PCR to evaluate mRNA levels of two isoforms of Mecp2, Mecp2e1 and Mecp2e2, at different time points after PHx.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Real-time", ...
PMC8009078
From Table 3, it can be seen the average RMSF value of 1.898, 1.595, 1.809, 1.719 and 2.001 Å was observed when bound to A1, A2, A3, A4 and A5, respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8956657
HB number of hydrogen bonds, SB number of salt bridges, NHB number of non-hydrogen bonds generated in PDBsum, BSA buried surface area calculated in PISA.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9000591
Thus, LCL, an EBV-transformed lymphoblastoid B-cell line, was selected as a benchmark in this study.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", "LCL", ",", "an", "E...
PMC9429973
Of the 2 patients in the persistent MRD-positivity after consolidation treatment cohort, 1 achieved MRD negativity and 1 had no response.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Of", "the", ...
PMC11653552
Che-1 overexpression in ADSC1 cells similarly results in increased miR-590-3p levels while downregulating TAZ and osteogenic differentiation markers (Fig. 2).
[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "token...
PMC10919056
Finally, this study further validated the differential expression of GJA5 and GJB1 in ccRCC using the oncopression database (http://www.oncopression.com/downloads.html) (Supplementary Figure 3.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973
of Oncology and Hematology, Università degli studi di Milano; Division of Hematology and Bone Marrow Transplant, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan; Department of Medicine, University of Verona, Verona; Division of hematology, Azienda Ospedaliera S. Croce e Carle, Cuneo, Italy Background: Infections ...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11748335
liftOver was employed to convert between different genome versions .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "liftOver", "was", "employed", "to", "convert", "between", "different", "genome", "versions", "." ] } ...
PMC8584666
However, the expression of the alternative-spliced form of GPI-80 mRNA was not observed in these tumor cell lines (Supplemental Figure S1a).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973
All patients identified were poor mobilizers and have eventually received Plerixafor either as pre-emptive use before first apheresis in those with peripheral CD34+ stem cells (PSC) <2.5 x10 cells/Kg, or after failure of first apheresis in those with PSC ≥2.5 x10 cells/Kg.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
The disadvantage of our method is a need for a fresh sample, which is investigated locally.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "disadvantage", "of", "our", "method", ...
PMC11536589
Two KRAS inhibitor MRTX1133-resistant PDAC cell lines were established in vitro.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Two", "KRAS", "inhibitor", "MRTX1133-resistant", "PDAC", "cell", "lines", "were", "establis...
PMC11188874
LLVY-R110 at a final concentration of 100 µmol/L was then added and incubated with cells for 18 hours under the same conditions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "LLVY-R110", ...
PMC11188874
D, Effect of HDAC6 inhibitors on autologous T cell–mediated myeloma cytotoxicity.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "D", ",", "Effect", "of", "HDAC6", "inhibitors", "on", "autologou...
PMC11488203
Subculture of all cancer cell lines was performed by trypsin/EDTA (Biochrom GmbH, Berlin, Germany) treatment for 5 min at 37 °C.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11201989
Membrane trafficking regulators such as the BBS proteins and the ras-related GTP-binding protein 8 (Rab8) also collaborate with the IFT machinery to control ciliary membrane biogenesis and the trafficking of membrane proteins to the cilium .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
We designed, therefore, this real-life study using decentralized assessment of MRD by MFC to solve the role of positive MRD at different times during treatment with standard chemotherapy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10669128
However, this requires the development of reliable and predictive tumor models to test only the most promising therapies in clinical trials.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",...
PMC11806818
Fig. 3(A) The preparation process of h-JHNzyme and the principle of SERS detection using h-JHNzyme.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "3(A", ")", "The", "preparation", "process", ...
PMC5311252
Interestingly, the clinical relevance of circulating cell-free miRNAs as biomarkers in cancer is currently being investigated intensively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interestingly", ",", "the", "clinical", ...
PMC6160470
On the other hand, P-gp ATPase inhibition can be achieved indirectly after the collapse of optimal membrane properties necessary for ABC transporter activity.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11082662
The statistical analysis and visualizations were performed using R v. 3.6.1 and GraphPad Prism 8.0 software (GraphPad Software, Inc., La Jolla, CA, USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11788920
Ramos cells were maintained in Roswell Park Memorial Institute (RPMI) medium with high glucose supplemented with 20% fetal bovine serum (FBS) and 1% antibiotics (streptomycin and penicillin) at 37°C in 5% CO2 in a humidified incubator.
[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10253973
Complex 34 (Figure 13) showed an IC50 value higher than 0.21 µM, while the IC50 of complex 35 (Figure 13) was higher than 2.14 µM. However, none of them were selective and able to inhibit HIV viruses in MT-4 cells .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11298021
This project was funded by Zanjan University of Medical Sciences, Zanjan, Iran (Grant No. A-12-190-28) and Shahid Beheshti University of Medical Sciences, Tehran, Iran (Grant No.27596, ethics code: IR.SBMU.RETECH.REC.1400.112).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11673128
Lipopolysaccharides compound (LPS) was bought from Sigma Aldrich (Burlington, MA, USA) and kept at −20 °C.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lipopol...
PMC10502403
The frequency of CD8NE1-Tetramer cells in infused NE1-GMCs was 62.2%. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "frequency", "of", "CD8NE1-Tetramer", "cells", "in", "infused", "NE1-GMCs", ...
PMC9583612
Stakeholders in the O&G industry, government, and financial organizations can adapt this framework for more representative emission estimation across the supply chain.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10820104
The crude extract (15 g) was fractionated through VLC (vacuum liquid chromatography) on silica gel as a stationary-phase with a gradient elution of solvents consisting of mixtures of n-hexane/EtOAc and CH2Cl2/MeOH, to afford seven fractions (A. ch Fr.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11352311
However, approximately 30% of patients present with metastatic tumors at the time of RCC diagnosis, which limits the potential for surgical intervention .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11204465
Difurocoumarolactone aflatoxins have a total of seven compounds, namely AFG1 (87), AFG2 (88), AFG2a (89), AFGM1 (90), AFGM2 (91), AFGM2a (92) (Figure 11).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11106977
Diabetes is known to exacerbate disc degeneration by increasing apoptosis and senescence in nucleus pulposus cells .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Diabetes", "is", "known", "to", "exacerbate", "disc", ...
PMC9429973
Summary/Conclusion: Treatment with MB-106, a third generation CD20 targeting CAR-T, resulted in high ORR and CR rates and CAR-T persistence in FL pts and was associated with favorable safety profile with no occurrence of Gr 3 or Gr 4 CRS and no ICANS event of any grade.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11772585
Interestingly, decreased levels of METTL1 have been observed in osteosarcoma, with low METTL1 expression playing an oncogenic role through the regulation of ferroptosis mediated by the pri-miR-26a/FTH1 axis .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11290772
After 48 h, ROBO1-NK cells almost completely eradicated the spindle-type primary tumor cells, whereas PBMC-NK cells left some residual cells (Figure 3E).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973
Here, we report our experience of three patients with post-transplant MRD-positive ALL who received blinatumomab and DLI.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Here", ",", "we", "report", "our", ...
PMC8348645
DPPH assay is carried out as per the method of Rajakumar et al. .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "DPPH", "assay", "is", "carried", "out", "as", "per", "the", "method",...
PMC9429973
After 5 cycles of blinatumomab, ponatinib was continued for at least 5 years.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "5", "cycles", "of", "blinatumomab", ",", "ponatinib", "...