OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11756907	However, this is certainly an issue that requires further research.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "this", "is", "certainly", "an", "issue", "that", "requires", "further...
PMC8873393	However, the functional significance of transcriptome dynamics and the mechanisms of chromatin attachment for thousands of unstudied human lncRNAs remain unclear.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",...
PMC11683240	Alpha-1-antitrypsin (α1AT) was identified from hemofiltrate library as PT inhibitor.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Alpha-1-antitrypsin", "(", "α1AT", ")", "was", "identified", "from", "hemofiltrate", ...
PMC6181431	We performed deep whole exome sequencing on the paired tumor samples and a blood sample.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "performed", "deep", "whole", "exome", "sequencing", "...
PMC9220170	Thus, despite the fact that both selenoproteins SELENOT and SELENOM belong to the same family of membrane proteins with thioredoxin-like folding and are localized in the ER, they have opposite effects on the expression of a number of pro-apoptotic genes in glioblastoma cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11763126	The beads were isolated, washed, and eluted, and the eluted products were then subjected to Western Blot analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "beads", "w...
PMC9429973	A univariable and multivariable analyses (MVA) adjusted for relevant clinical variables were conducted to assess the impact of socio-economic variables on several outcomes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9812014	An asparagine amino acid residue in the glycoprotein of this virus has a linked oligosaccharide moiety (GlcNAc2, Man9, Glc3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "An", ...
PMC11347429	Blood samples from healthy controls were taken from hospital visitors, hospital patients with no respiratory or other infections or inflammatory disorders, and volunteers at the Helmholtz Centre for Infection Research, Braunschweig.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11295144	The % area values were normalized to the expression of NL2 for each cell.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "%", "area", "values", "were", "normalized", "to", "the", ...
PMC11469524	Thus, we performed the same perturbations experiment that was conducted on BL-2 cells on a different BL cell line, BL-41, (Fig 2A) and subsequently applied the same modeling strategy (cf.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "...
PMC11320834	The concentration-dependent response of different ovarian cancer cell types to combination therapy confirms the need for in vitro optimization to maximize drug cytotoxicity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC11627133	All bifunctional and individual aptamers were in vitro transcribed, purified by polyacrylamide gel electrophoresis, and in vitro characterized (Figure S1, Table S1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11519583	Therefore, future investigations should aim to determine whether Ror2 signaling, activated by Wnt5b and Wnt11, exacerbates pathological conditions, utilizing alternative pathological models such as mdx mice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11055510	Therefore, we believed that IL1RAP was an important target to study the mechanism of miR-135a-3p in OC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "we", "believed", "th...
PMC11286266	FURIN protein levels were determined using horseradish peroxidase (HRP) or IRDye fluorescently labelled secondary antibodies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "FURIN", "protein", "levels", "were", "determined"...
PMC11279598	Further, another mechanism we found contributing to the effects of MH is through activation of AMPK and inhibition of the AKT/mTOR downstream pathway.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11443022	Treatment with amoxapine, a tricyclic antidepressant, proved ineffective.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Treatment", "with", "amoxapine", ",", "a", "tricyclic", "antidepressant", ",", "proved", "ineffe...
PMC9429973	These data provide the rationale to initiate clinical trials with the combination of tolinapant and decitabine.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "data", "provide", "the", "rationale", "to", ...
PMC11529598	Collectively, these data suggested that miR-3154 prevents glioblastoma cells from apoptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Collectively", ",", "these", "data", "suggested", "that", "miR-3154", "prevents", ...
PMC11471176	L- Carnosine was purchased from (GE5095, Glentham Life Sciences Ltd, Corsham, United Kingdom) and stored below 25 °C until use.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC8735881	Infection curves of the transduced CEMss-CCR5 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Infection", "curves", "of", "the", "transduced", "CEMss-CCR5", "cells", "." ] } ]
PMC6600253	For instance, in a study by Martí-Centelles, several stilbene derivatives were prepared, and their cytotoxic activity was evaluated .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "instance", ...
PMC11144200	The smallest known integrin identification sequence capable of binding to the αvβ3 receptor is thought to be RGD tripeptide .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "smallest", "known", "integ...
PMC11604830	Anatomical T2‐weighted images overlaid with CSI images at 3.71 ppm are shown in the top part of the figure: (A) before, (B) 4, and (C) 24 h post iv injection of PFCE‐NE (50 mmol protons/kg bw).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10048572	In Jurkat-O1 subclones, EMAST was observed in 111 of 381 subclones (29%), respectively.	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "Jurkat-O1", "subclones", ",",...
PMC11745600	Owing to severe diabetes, all male and female Ins1 NOG mice experienced premature mortality by 60 and 64 wk of age, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11116779	In the atmosphere, the decomposition process continues through the reduction of the particles’ size in a time-dependent manner, leading to the formation of nanoplastics (NPs), defined as particles 1 nm ≤ x ≤ 1 μm (2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9621239	Chromatin licensing and DNA replication factor 1 (CDT1) are also involved in the regulation of DNA replication, and the overexpression of CDT1 could lead to genome instability.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	There was no significant difference in these baseline characteristics between both groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "was", "no", "significant", "difference", "in", "these", "baseline", "ch...
PMC9429973	Additionally, all Dynamic International Prognostic Scoring System (DIPSS)-Plus criteria reported were considered.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "all", "Dynamic", "International", "Prognostic", "Scoring", ...
PMC8357004	The histone deacetylase inhibitors (HDACIs) reactivate the INK4 and CIP/CIP gene families causing G1 phase arrest.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "histone", "deacetylase", "inhibitors"...
PMC11656657	Mice were maintained in the animal facility at Plaisant Castel Romano (Rome, Italy).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mice", "were", "maintained", "in", "the", "animal", ...
PMC9429973	The time-varying AUC was consistently higher for the stacking-model compared to IPS-models within the first five years after diagnosis (Figure).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "time-...
PMC11106977	The Wnt signaling pathway can be divided into two main pathways, the canonical pathway, and the non-canonical pathway.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "Wnt", "signaling", ...
PMC3995603	Standard stock solutions of three phenolic acids (chlorogenic acid, caffeic acid and isochlorogenic acid A), two flavonoids (hyperoside and isoquercitrin) and one coumarin (scoparone) (Figure 1A) were dissolved in methanol at concentrations of 1.0 mg/mL and kept at 4°C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11653533	In addition, the hydroalcoholic extract of Ficus racemosa has conveyed antibacterial activity against Actinomyces viscosus with a MIC concentration of 0.08 mg/ml (Shaikh et al., 2010).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	B. Paul, M. Liedtke, D. S. Siegel, J. Khouri, J. Hillenglass, R. Rifkin, M. D. Gandhi, A. Kin, M. Y. Levy, A. Mohrbacher, W. Schmidt, R. Silbermann, F. Cottini, D. W. Sborov, R. Walker, M. Murphy, L. Gu, A. Chen, N. Rajakumaraswamy, S. Z. Usmani Levine Cancer Institute, Charlotte; Stanford Cancer Institute, Stanford; J...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8956657	C Co-immunoprecipitation (coIP) assay against HA-tagged IMPα isoforms and probed for the presence of full-length FLAG-tagged MERS-CoV ORF4b.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "C", "Co-immunoprecipitation", ...
PMC11394112	These data suggest that the NSG-IL6 mice are highly permissive to both ABC and GCB subtypes of DLBCL cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "data", "suggest", ...
PMC8526701	The cells were incubated with MTT for 1 h with dimethyl sulfoxide (Sigma, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cells", "were", "incubated", "with", ...
PMC11721277	The reaction mixture was extracted with CH2Cl2 (20 mL), washed with water (2 × 20 mL), and then the organic phase was dried with anhydrous Na2SO4 and concentrated under reduced pressure.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10813895	Clarifying how aging regulates ELF5-expressed cells will be instrumental in designing strategies to target ELF5, its downstream genes, and its regulatory pathways.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	She received 3 cycles of ESHAP achieving PR, and an haploidentical stem cell transplantation was performed in January/22.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "She", "received", "3", "cycles", ...
PMC11247842	Although meta-analysis and post-GWAS analyses help to define QTL regions, the problem remains how to discriminate the causative variants from linked polymorphisms.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Althoug...
PMC11371627	Here, the finding of elevated activated T cells and NKs indicate an immune-cell-mediated response in the CNS which might trigger a greater susceptibility to perception of muscular weakness and reduced physical strength after COVID-19 disease that then led to subjective notification of first symptoms of XK-disease in ou...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9952933	Here, the concentration declined in the supernatants of all cell lines (Figure 4E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Here", ",", "the", "concentration", "declined", "in", ...
PMC9024365	These results coincide with an increase in cluster size when stratified for co-localization with GluA1 or GluA2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "results", "coincide", "with", "an", ...
PMC11499955	We observed quantitative detachment of the TMPP tags from the antibodies in a few minutes using excess cyclooctyne DBCO.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "observed", "quantitative", ...
PMC9545474	In this experiment, A2780 cells were treated with either complex 6 or 8 for 24 h at 2 × IC50 concentrations, or doxorubicin (0.5 μM) for comparative purposes (Figure 9 and Tables S12‐S14 to show the full numerical data and statistical analysis of results).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11746948	Additionally, GPX4 transcript levels were unaffected by APT2 knockdown (Fig. 5f).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "GPX4", "transcript", "levels", "were", "unaffecte...
PMC11750712	The magnifications of the orange circled cells show overlay (top), CD3 staining (center) and CD34 staining (bottom).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11806182	Functional enrichment analysis showed that up-regulated module ME1 was related to focal adhesion, while down-regulated module ME2 was linked to the cell cycle.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11742431	Scale bar, 50 µm. **	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", ",", "50", "µm", ".", "", "" ] } ]
PMC11686380	She had difficulty studying and attended a special support class.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "She", "had", "difficulty", "studying", "and", "attended", "a", "special", "support", "class", ...
PMC8633974	U1 and JLat cells contain one or more integrated copies of the viral genome in each cell.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "U1", "and", "JLat", "cells", "contain", ...
PMC9429973	However, in contrast to HL, no clear rebound was seen and AMH values remained extremely low, even at 18 months after the end of treatment (median values: 0,23IU/mL), highlighting the gonadotoxic effect of CT.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11633763	Research advances in cancer research have improved the treatment of patients with osteosarcoma; however, patient prognosis remains relatively poor.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Research", "advances", ...
PMC11733919	Lysosomal localization of the nanoplatform was confirmed by colocalization analysis of lysosomal senescence-associated beta-galactosidase activity using a CellEvent senescence green detection kit (Thermo Fisher Scientific, Waltham, MA, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10748106	Additionally, to verify the difference in the chemical natures between Geniposide and its aglycone Genipin, we performed a molecular similarity analysis by the CFD alignment that is shown in Figure S6.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11755467	Nevertheless, these data are in line with our finding that only one out of eight tested miRNAs—namely hsa-miR-132—was influenced by Enoxacin administration.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11674441	Additional detailed pathological information is provided in Supplementary Table S1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additional", "detailed", "pathological", "information", "is", "provided", "in", "Supplementary", "Tabl...
PMC11513011	In T24, DIB increased the expression of E-cadherin at.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "T24", ",", "DIB", "increased", "the", "expression", "of", "E-cadherin", "at", "." ...
PMC10747160	We also found that mutating Griffithsin to abolish its bivalent binding capability (GLG-3A) led to attenuated antiviral activity on the same pseudoviral direct infectivity assays (Figure 3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11297139	We then sought to comprehensively identify the regions of ARID1A that are responsible for driving LLPS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "then", "sought", "to", "comprehensively", "ident...
PMC8916024	This implied that the gut microenvironment of the snail is in a relatively stable state.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "implied", "that", "the", "gut", "microenvironment", ...
PMC9429973	In contrast to mHSPC expressing wild-type STAT3, the Y640F-mutated variant resulted in a strong inflammatory gene expression signature that was characterized by overactivation of TNF alpha/Interferon gamma pathways, and is conserved in T-LGLL patients harbouring STAT3 mutations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11621565	Data are expressed as the mean ± SEM of four independent experiments carried out in duplicate (for curli CsgA 16 µg/ml and PSMα1 16 µg/ml – three independent experiments carried out in duplicate).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11785489	If T cells assigned to the same antigen specificity based on Dextramer UMI counts really do share antigen specifiity, they should have similar TCR sequences.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11317131	After three days, cells were lysed for analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "three", "days", ",", "cells", "were", "lysed", "for", "analysis", "." ] } ]
PMC11767725	The reduction in filaggrin levels compromises the production of natural moisturizing factors, which are derived from filaggrin degradation and include hygroscopic molecules such as urocanic acid and pyrrolidone carboxylic acid.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11337594	Furthermore, the impact of TER on A375 cell invasion was investigated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "the", "impact", "of", "TER", "on", "A375", "cell", ...
PMC9429973	Patient/disease characteristics, therapy and survival were compared between patients who received Ig by 24 months of diagnosis and patients who did not, using chi-square tests for categorical variables and rank sum tests for continuous variables.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10154097	Patients with high circSOX4 level had significantly reduced survival (P < 0.05) compared to the low-expression group (Figure 1(c)).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11515150	no significance) (d) Statistical analysis of the bioluminescence intensity of each group at different days (n = 4; two-way ANOVA; p < 0.05, ***p < 0.0001; n.s.,	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10047551	Adjustment for this factor by comparing the effect of dSaCas9-TET1 relative to dSaCas9-dTET1 revealed a non-significant trend of increased PD-L1 mRNA expression (Figure 4B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973	Logistic regression analysis demonstrated similar trends (Figure): patients aged 55-64 and 65-74 years had numerically higher odds of receiving HMA therapy (odds ratio [OR] 2.29, p=0.05, and 2.04, p=0.11, respectively) than those aged ≥75 years (OR 1.13, p=0.79; reference group 18-54 years); females were less likely to...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10898159	Using Genome-scale CRISP screening, the chromatin modifying enzymes, KAT6A/MOZ and KMT2A/MLL1 was found to be co-dependent and co-localized with GIST-associated genes and regulate oncogenic transcription and cell cycle progression by regulating transcription factor gene expression programs .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	CLL in patients with two other common ATM VUS, p.S707P and p.F858L, was also significantly enriched for ATM-aberrant disease.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CLL", ...
PMC11277157	Another neuronal-like gene is SYT16, a calcium-independent membranous protein involved in the trafficking of secretory vesicles in non-neuronal tissues.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Another", "neuronal-like", "...
PMC10565698	N. Changes in EMT pathway-related proteins in HCCLM3 and BEL-7407 cells under different transfection conditions were detected by western blotting. **:	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens"...
PMC3931643	This led us to test whether modulating the stoichiometry of the cap translation complex would sensitize VAL cells to asTORi treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O" ], "tokens": [ "This", "led", ...
PMC8609870	The above studies show that GRIA1 plays an important role in diseases related to pregnancy in women.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "above", "studies", "show", "that", "...
PMC9429973	We report here a case of high risk myelodysplastic syndrome (HR-MDS) after CAR-T cell treatment for relapsed diffuse large B cell lymphoma (DLBCL).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10810426	Raw data for all figures are deposited as a Mendeley dataset at https://data.mendeley.com/datasets/zmgp7dsj3m/1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Raw", "data", "for", "all", "figures", "are", "deposited", "as", "a",...
PMC9429973	Median OS was comparable to reference patients (52.6 months [95% CI: 46.3–62.0] vs. 55.0 months [95% CI: 51.6–58.9], p=0.504).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11486946	Because daunorubicin has an auto-fluorescence in the nucleus at 488 nm excitation, EGFR was observed using a second antibody at 640 nm excitation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC8753818	Compared with the native CHO-K1 cell line, the caspase-7 deficient clone represented an average of 1.7-fold increase in specific luciferase expression.	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Compared"...
PMC8068766	HepG2 and HepG2-2.2.15 cells were clustered separately again (Figure 3b).	[ { "tags": [ "B-CellLine", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HepG2", "and", "HepG2", "-", "2.2.15", "...
PMC11701801	In the present study, we found that expression of KREMEN2 increased in cells deficient in both SMARCA4 and SMARCA2 contained within cBAF, PBAF, and ncBAF.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10094712	Despite the fact that earlier we were able to select the conditions for the production of the cysteine homologue hSELENOM, in the framework of this work we further improved them, which allowed us to obtain an even higher yield of purified protein (up to 10 mg/mL), taking into account the fact that this protein tends to...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9024365	We conclude that the minimal M4/CT domain of GluA2 is sufficient for clustering with SD1, which potentially explains the lack of SD1 effects on biophysical properties.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11785489	To assess the statistical significance of each canonical correlation, we permuted our data 1,000 times and re-applied rCCA (STAR Methods).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", ...
PMC6133382	A detailed plot of this data is show in Fig 4A. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "detailed", "plot", "of", "this", "data", "is", "show", "in", "Fig", ...
PMC11705484	Silencing TRMT61A inhibited 5637 cell proliferation, clonogenicity, migration and invasion, while its overexpression was promoted in T24 cells (Figure S1A,B and Figure 1A–F).	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "...
PMC9429973	Z. Zhuang, Y. Tian, L. Shi, D. Zou, R. Feng, W.-W. Tian, H. Yu, F. Dong, A. Liao, Y. Ma, Q. Liu, S. Liu, H. Jing, R. Fu, L.-M. Ma, H. Liu, W. Sun, L. Bao, Y. Wu, W. Chen, J. Zhuang Department of Hematology, Peking Union Medical College Hospital; Department of Hematology, Beijing Chao-Yang Hospital of Capital Medical Un...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10812665	This has, e.g., allowed a large screen for mito-toxicants, followed by a mechanistic characterization of the hits as, e.g., uncouplers or c-I inhibitors .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4443654	This supports the idea that these cell-type-specific regions are undergoing compartment-level transitions, disproportionately mediated by the formation of long-range contacts, while also not precluding additional changes at lower levels such as TADs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11545868	It is mainly found in Dalbergia sissoo and Trifolium pratense (Figure 4).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "mainly", "found", "in", "Dalbergia", "sissoo", "and"...
PMC11412721	Quantifications are relative to actin.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Quantifications", "are", "relative", "to", "actin", "." ] } ]

PMC11756907

However, this is certainly an issue that requires further research.

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PMC8873393

However, the functional significance of transcriptome dynamics and the mechanisms of chromatin attachment for thousands of unstudied human lncRNAs remain unclear.

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PMC11683240

Alpha-1-antitrypsin (α1AT) was identified from hemofiltrate library as PT inhibitor.

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PMC6181431

We performed deep whole exome sequencing on the paired tumor samples and a blood sample.

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PMC9220170

Thus, despite the fact that both selenoproteins SELENOT and SELENOM belong to the same family of membrane proteins with thioredoxin-like folding and are localized in the ER, they have opposite effects on the expression of a number of pro-apoptotic genes in glioblastoma cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11763126

The beads were isolated, washed, and eluted, and the eluted products were then subjected to Western Blot analysis.

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PMC9429973

A univariable and multivariable analyses (MVA) adjusted for relevant clinical variables were conducted to assess the impact of socio-economic variables on several outcomes.

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PMC9812014

An asparagine amino acid residue in the glycoprotein of this virus has a linked oligosaccharide moiety (GlcNAc2, Man9, Glc3).

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PMC11347429

Blood samples from healthy controls were taken from hospital visitors, hospital patients with no respiratory or other infections or inflammatory disorders, and volunteers at the Helmholtz Centre for Infection Research, Braunschweig.

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PMC11295144

The % area values were normalized to the expression of NL2 for each cell.

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PMC11469524

Thus, we performed the same perturbations experiment that was conducted on BL-2 cells on a different BL cell line, BL-41, (Fig 2A) and subsequently applied the same modeling strategy (cf.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "...

PMC11320834

The concentration-dependent response of different ovarian cancer cell types to combination therapy confirms the need for in vitro optimization to maximize drug cytotoxicity.

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PMC11627133

All bifunctional and individual aptamers were in vitro transcribed, purified by polyacrylamide gel electrophoresis, and in vitro characterized (Figure S1, Table S1).

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PMC11519583

Therefore, future investigations should aim to determine whether Ror2 signaling, activated by Wnt5b and Wnt11, exacerbates pathological conditions, utilizing alternative pathological models such as mdx mice.

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PMC11055510

Therefore, we believed that IL1RAP was an important target to study the mechanism of miR-135a-3p in OC.

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PMC11286266

FURIN protein levels were determined using horseradish peroxidase (HRP) or IRDye fluorescently labelled secondary antibodies.

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PMC11279598

Further, another mechanism we found contributing to the effects of MH is through activation of AMPK and inhibition of the AKT/mTOR downstream pathway.

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PMC11443022

Treatment with amoxapine, a tricyclic antidepressant, proved ineffective.

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PMC9429973

These data provide the rationale to initiate clinical trials with the combination of tolinapant and decitabine.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "data", "provide", "the", "rationale", "to", ...

PMC11529598

Collectively, these data suggested that miR-3154 prevents glioblastoma cells from apoptosis.

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PMC11471176

L- Carnosine was purchased from (GE5095, Glentham Life Sciences Ltd, Corsham, United Kingdom) and stored below 25 °C until use.

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PMC8735881

Infection curves of the transduced CEMss-CCR5 cells.

[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Infection", "curves", "of", "the", "transduced", "CEMss-CCR5", "cells", "." ] } ]

PMC6600253

For instance, in a study by Martí-Centelles, several stilbene derivatives were prepared, and their cytotoxic activity was evaluated .

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PMC11144200

The smallest known integrin identification sequence capable of binding to the αvβ3 receptor is thought to be RGD tripeptide .

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PMC11604830

Anatomical T2‐weighted images overlaid with CSI images at 3.71 ppm are shown in the top part of the figure: (A) before, (B) 4, and (C) 24 h post iv injection of PFCE‐NE (50 mmol protons/kg bw).

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PMC10048572

In Jurkat-O1 subclones, EMAST was observed in 111 of 381 subclones (29%), respectively.

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PMC11745600

Owing to severe diabetes, all male and female Ins1 NOG mice experienced premature mortality by 60 and 64 wk of age, respectively.

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PMC11116779

In the atmosphere, the decomposition process continues through the reduction of the particles’ size in a time-dependent manner, leading to the formation of nanoplastics (NPs), defined as particles 1 nm ≤ x ≤ 1 μm (2).

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PMC9621239

Chromatin licensing and DNA replication factor 1 (CDT1) are also involved in the regulation of DNA replication, and the overexpression of CDT1 could lead to genome instability.

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PMC9429973

There was no significant difference in these baseline characteristics between both groups.

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PMC9429973

Additionally, all Dynamic International Prognostic Scoring System (DIPSS)-Plus criteria reported were considered.

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PMC8357004

The histone deacetylase inhibitors (HDACIs) reactivate the INK4 and CIP/CIP gene families causing G1 phase arrest.

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PMC11656657

Mice were maintained in the animal facility at Plaisant Castel Romano (Rome, Italy).

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PMC9429973

The time-varying AUC was consistently higher for the stacking-model compared to IPS-models within the first five years after diagnosis (Figure).

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PMC11106977

The Wnt signaling pathway can be divided into two main pathways, the canonical pathway, and the non-canonical pathway.

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PMC3995603

Standard stock solutions of three phenolic acids (chlorogenic acid, caffeic acid and isochlorogenic acid A), two flavonoids (hyperoside and isoquercitrin) and one coumarin (scoparone) (Figure 1A) were dissolved in methanol at concentrations of 1.0 mg/mL and kept at 4°C.

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PMC11653533

In addition, the hydroalcoholic extract of Ficus racemosa has conveyed antibacterial activity against Actinomyces viscosus with a MIC concentration of 0.08 mg/ml (Shaikh et al., 2010).

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PMC9429973

B. Paul, M. Liedtke, D. S. Siegel, J. Khouri, J. Hillenglass, R. Rifkin, M. D. Gandhi, A. Kin, M. Y. Levy, A. Mohrbacher, W. Schmidt, R. Silbermann, F. Cottini, D. W. Sborov, R. Walker, M. Murphy, L. Gu, A. Chen, N. Rajakumaraswamy, S. Z. Usmani Levine Cancer Institute, Charlotte; Stanford Cancer Institute, Stanford; J...

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PMC8956657

C Co-immunoprecipitation (coIP) assay against HA-tagged IMPα isoforms and probed for the presence of full-length FLAG-tagged MERS-CoV ORF4b.

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PMC11394112

These data suggest that the NSG-IL6 mice are highly permissive to both ABC and GCB subtypes of DLBCL cell lines.

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PMC8526701

The cells were incubated with MTT for 1 h with dimethyl sulfoxide (Sigma, USA).

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PMC11721277

The reaction mixture was extracted with CH2Cl2 (20 mL), washed with water (2 × 20 mL), and then the organic phase was dried with anhydrous Na2SO4 and concentrated under reduced pressure.

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PMC10813895

Clarifying how aging regulates ELF5-expressed cells will be instrumental in designing strategies to target ELF5, its downstream genes, and its regulatory pathways.

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PMC9429973

She received 3 cycles of ESHAP achieving PR, and an haploidentical stem cell transplantation was performed in January/22.

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PMC11247842

Although meta-analysis and post-GWAS analyses help to define QTL regions, the problem remains how to discriminate the causative variants from linked polymorphisms.

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PMC11371627

Here, the finding of elevated activated T cells and NKs indicate an immune-cell-mediated response in the CNS which might trigger a greater susceptibility to perception of muscular weakness and reduced physical strength after COVID-19 disease that then led to subjective notification of first symptoms of XK-disease in ou...

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PMC9952933

Here, the concentration declined in the supernatants of all cell lines (Figure 4E).

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PMC9024365

These results coincide with an increase in cluster size when stratified for co-localization with GluA1 or GluA2.

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PMC11499955

We observed quantitative detachment of the TMPP tags from the antibodies in a few minutes using excess cyclooctyne DBCO.

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PMC9545474

In this experiment, A2780 cells were treated with either complex 6 or 8 for 24 h at 2 × IC50 concentrations, or doxorubicin (0.5 μM) for comparative purposes (Figure 9 and Tables S12‐S14 to show the full numerical data and statistical analysis of results).

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PMC11746948

Additionally, GPX4 transcript levels were unaffected by APT2 knockdown (Fig. 5f).

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PMC11750712

The magnifications of the orange circled cells show overlay (top), CD3 staining (center) and CD34 staining (bottom).

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PMC11806182

Functional enrichment analysis showed that up-regulated module ME1 was related to focal adhesion, while down-regulated module ME2 was linked to the cell cycle.

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PMC11742431

Scale bar, 50 µm. **

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PMC11686380

She had difficulty studying and attended a special support class.

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PMC8633974

U1 and JLat cells contain one or more integrated copies of the viral genome in each cell.

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PMC9429973

However, in contrast to HL, no clear rebound was seen and AMH values remained extremely low, even at 18 months after the end of treatment (median values: 0,23IU/mL), highlighting the gonadotoxic effect of CT.

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PMC11633763

Research advances in cancer research have improved the treatment of patients with osteosarcoma; however, patient prognosis remains relatively poor.

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PMC11733919

Lysosomal localization of the nanoplatform was confirmed by colocalization analysis of lysosomal senescence-associated beta-galactosidase activity using a CellEvent senescence green detection kit (Thermo Fisher Scientific, Waltham, MA, USA).

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PMC10748106

Additionally, to verify the difference in the chemical natures between Geniposide and its aglycone Genipin, we performed a molecular similarity analysis by the CFD alignment that is shown in Figure S6.

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PMC11755467

Nevertheless, these data are in line with our finding that only one out of eight tested miRNAs—namely hsa-miR-132—was influenced by Enoxacin administration.

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PMC11674441

Additional detailed pathological information is provided in Supplementary Table S1.

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PMC11513011

In T24, DIB increased the expression of E-cadherin at.

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PMC10747160

We also found that mutating Griffithsin to abolish its bivalent binding capability (GLG-3A) led to attenuated antiviral activity on the same pseudoviral direct infectivity assays (Figure 3).

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PMC11297139

We then sought to comprehensively identify the regions of ARID1A that are responsible for driving LLPS.

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PMC8916024

This implied that the gut microenvironment of the snail is in a relatively stable state.

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PMC9429973

In contrast to mHSPC expressing wild-type STAT3, the Y640F-mutated variant resulted in a strong inflammatory gene expression signature that was characterized by overactivation of TNF alpha/Interferon gamma pathways, and is conserved in T-LGLL patients harbouring STAT3 mutations.

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PMC11621565

Data are expressed as the mean ± SEM of four independent experiments carried out in duplicate (for curli CsgA 16 µg/ml and PSMα1 16 µg/ml – three independent experiments carried out in duplicate).

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PMC11785489

If T cells assigned to the same antigen specificity based on Dextramer UMI counts really do share antigen specifiity, they should have similar TCR sequences.

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PMC11317131

After three days, cells were lysed for analysis.

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PMC11767725

The reduction in filaggrin levels compromises the production of natural moisturizing factors, which are derived from filaggrin degradation and include hygroscopic molecules such as urocanic acid and pyrrolidone carboxylic acid.

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PMC11337594

Furthermore, the impact of TER on A375 cell invasion was investigated.

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PMC9429973

Patient/disease characteristics, therapy and survival were compared between patients who received Ig by 24 months of diagnosis and patients who did not, using chi-square tests for categorical variables and rank sum tests for continuous variables.

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PMC10154097

Patients with high circSOX4 level had significantly reduced survival (P < 0.05) compared to the low-expression group (Figure 1(c)).

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PMC11515150

no significance) (d) Statistical analysis of the bioluminescence intensity of each group at different days (n = 4; two-way ANOVA; *p < 0.05, ****p < 0.0001; n.s.,

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PMC10047551

Adjustment for this factor by comparing the effect of dSaCas9-TET1 relative to dSaCas9-dTET1 revealed a non-significant trend of increased PD-L1 mRNA expression (Figure 4B).

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PMC9429973

Logistic regression analysis demonstrated similar trends (Figure): patients aged 55-64 and 65-74 years had numerically higher odds of receiving HMA therapy (odds ratio [OR] 2.29, p=0.05, and 2.04, p=0.11, respectively) than those aged ≥75 years (OR 1.13, p=0.79; reference group 18-54 years); females were less likely to...

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PMC10898159

Using Genome-scale CRISP screening, the chromatin modifying enzymes, KAT6A/MOZ and KMT2A/MLL1 was found to be co-dependent and co-localized with GIST-associated genes and regulate oncogenic transcription and cell cycle progression by regulating transcription factor gene expression programs .

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PMC9429973

CLL in patients with two other common ATM VUS, p.S707P and p.F858L, was also significantly enriched for ATM-aberrant disease.

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PMC11277157

Another neuronal-like gene is SYT16, a calcium-independent membranous protein involved in the trafficking of secretory vesicles in non-neuronal tissues.

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PMC10565698

N. Changes in EMT pathway-related proteins in HCCLM3 and BEL-7407 cells under different transfection conditions were detected by western blotting. **:

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PMC3931643

This led us to test whether modulating the stoichiometry of the cap translation complex would sensitize VAL cells to asTORi treatment.

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PMC8609870

The above studies show that GRIA1 plays an important role in diseases related to pregnancy in women.

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PMC9429973

We report here a case of high risk myelodysplastic syndrome (HR-MDS) after CAR-T cell treatment for relapsed diffuse large B cell lymphoma (DLBCL).

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PMC10810426

Raw data for all figures are deposited as a Mendeley dataset at https://data.mendeley.com/datasets/zmgp7dsj3m/1.

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PMC9429973

Median OS was comparable to reference patients (52.6 months [95% CI: 46.3–62.0] vs. 55.0 months [95% CI: 51.6–58.9], p=0.504).

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PMC11486946

Because daunorubicin has an auto-fluorescence in the nucleus at 488 nm excitation, EGFR was observed using a second antibody at 640 nm excitation.

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PMC8753818

Compared with the native CHO-K1 cell line, the caspase-7 deficient clone represented an average of 1.7-fold increase in specific luciferase expression.

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PMC8068766

HepG2 and HepG2-2.2.15 cells were clustered separately again (Figure 3b).

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PMC11701801

In the present study, we found that expression of KREMEN2 increased in cells deficient in both SMARCA4 and SMARCA2 contained within cBAF, PBAF, and ncBAF.

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PMC10094712

Despite the fact that earlier we were able to select the conditions for the production of the cysteine homologue hSELENOM, in the framework of this work we further improved them, which allowed us to obtain an even higher yield of purified protein (up to 10 mg/mL), taking into account the fact that this protein tends to...

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PMC9024365

We conclude that the minimal M4/CT domain of GluA2 is sufficient for clustering with SD1, which potentially explains the lack of SD1 effects on biophysical properties.

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PMC11785489

To assess the statistical significance of each canonical correlation, we permuted our data 1,000 times and re-applied rCCA (STAR Methods).

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PMC6133382

A detailed plot of this data is show in Fig 4A. (

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PMC11705484

Silencing TRMT61A inhibited 5637 cell proliferation, clonogenicity, migration and invasion, while its overexpression was promoted in T24 cells (Figure S1A,B and Figure 1A–F).

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PMC9429973

Z. Zhuang, Y. Tian, L. Shi, D. Zou, R. Feng, W.-W. Tian, H. Yu, F. Dong, A. Liao, Y. Ma, Q. Liu, S. Liu, H. Jing, R. Fu, L.-M. Ma, H. Liu, W. Sun, L. Bao, Y. Wu, W. Chen, J. Zhuang Department of Hematology, Peking Union Medical College Hospital; Department of Hematology, Beijing Chao-Yang Hospital of Capital Medical Un...

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PMC10812665

This has, e.g., allowed a large screen for mito-toxicants, followed by a mechanistic characterization of the hits as, e.g., uncouplers or c-I inhibitors .

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PMC4443654

This supports the idea that these cell-type-specific regions are undergoing compartment-level transitions, disproportionately mediated by the formation of long-range contacts, while also not precluding additional changes at lower levels such as TADs.

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PMC11545868

It is mainly found in Dalbergia sissoo and Trifolium pratense (Figure 4).

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PMC11412721

Quantifications are relative to actin.

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