OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC9817179	Confocal fluorescence microscopy was performed on Zeiss LSM 980 in the point-scanning mode with a ×63 oil objective (Zeiss, 421782-9900-000).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5833712	Moreover, we have shown that KB9520-activated ERβ has a strong stimulatory effect on KDM6B expression, that most likely add to the ERβ-mediated ovarian tumor inhibitory activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11286266	S–S indicates for the disulphide bond in the LD between two cysteines. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "S", "–", "S", "indicates", "for", "the", "disulphide", ...
PMC9429973	During cycle 3, 5.3% showed anemia ≥grade 3, 10.5% showed thrombocytopenia ≥grade 3, while 15.8% showed lymphopenia ≥grade 3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11543935	The electrode mounting interface developed in this study combines these requirements by ensuring a reliable electrode placement while being able to adjust the electrode distance and having an access point for the temperature sensor.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11739504	SDCCAG3 has also been reported to localize to the basal body and interact with IFT88.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SDCCAG3", "has", "also", "been", "reported", "to", "localiz...
PMC11411131	Cos-7 cells transiently expressing Krab-Sec/Luc were treated with 20 µM MeHg for 24 h (Fig. 6A).	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cos-7", "cells", "transiently", "ex...
PMC11413393	An MS1 ion scan was performed at 60,000 FWHM followed by MS/MS scans (HCD, 15,000 fwhm) of up to 20 parent ions (minimum activation of 1000).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11680562	While the plain gel showed no inhibition, the CuO NPs displayed significant inhibition (22.35 ± 49 mm), and the PXFCu6 gel exhibited the largest zone (52.05 ± 1.37 mm), demonstrating the superior antibacterial activity, indicating that it may protect the vagina and lower the risk of infections like aerobic vaginitis an...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11641532	Principal components were selected based on the following criteria: cumulative contribution >90%, individual component variance contribution <5%, and the difference between two consecutive components <0.1%.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11792766	Differences were considered to be statistically significant when p < 0.05; p < 0.01; **p < 0.001.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	Image: Summary/Conclusion: This real-life study demonstrated an improved outcome among FLT3mut AML patients treated in the most recent period, probably reflecting the beneficial effect of midostaurin on relapse prevention in this context.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11323699	ovarian carcinoma cells injected either subcutaneously (SC) or intraperitoneally (IP).	[ { "tags": [ "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ovarian", "carcinoma", "cells", "injected", "either", ...
PMC11721587	The remaining pellet was extracted with 10 mM tris-HCl (pH 7.5), 300 mM NaCl, and 1% NP 40 to yield nuclear fraction.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11701801	Ten percent of lung cancer and most of small cell carcinoma of the ovary, hypercalcemic type (SCCOHT), are deficient in both SMARCA4 and SMARCA2 (10, 11).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5600151	MVP overexpression in cancer cells is involved in transporting drugs away from the nucleus, and is thus related to multidrug resistance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MVP", "overe...
PMC11588085	Then, an mRNA stemness index is calculated for each subgroup of tumors belonging to the first quartile (high) and the last quartile (low) of XIST expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Corticosteroid prophylaxis and step-up dosing of epcoritamab were required in cycle 1 to mitigate CRS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Corticosteroid", "prophylaxis", "and", "step-up", "dosing", "of",...
PMC11718109	Scale bar, 500 nm.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", ",", "500", "nm", "." ] } ]
PMC10387886	Immunoreactive bands were visualized by using chemiluminescence (Luminata Forte HRP Substrate, Millipore) in ChemiDoc™ MP Imaging System (Bio-Rad).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	Results: The platelet aggregation was tested in 69 patients with MPN on ASA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "The", "platelet", "aggregation", "was", "tested", ...
PMC11718031	Subsequently, cells are passaged in the same basal medium or a combination of the basal medium and a feed to adapt the cells for bioreactor cultivation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11656657	At the endpoint the percentage of residual tumor was evaluated by FACS as measure of GFP tumor expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "the", "endpoint", "the", "percen...
PMC11298021	The present study aimed to investigate the potential cytotoxic effects of rapamycin and PI3K/AKT/mTOR inhibitory miRNAs, alone or in combination, against NOTCH1-driven T-ALL.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC8143558	The results for E. camaldulensis Dehnh also confirm variations in the saponin content when different solvents are used to extract the same part of the plant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11737091	Another study conducted by Zhang et al. demonstrated that DBF4 promotes STAT3 signaling activation in hepatocellular carcinoma cells via a CDC7-mediated and XPO1-dependent mechanism .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11604830	The squares pictured in the image correspond to the voxels acquired by PRESS: Black, PLN of the left leg; red, PLN of the right leg (tumor‐bearing side); orange, pure low‐gelling agar; yellow, PFCE‐NE in low‐gelling agar (0.66 M proton concentration).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Lymph2Cx-based assay was successful in 38 cases and classified 16 cases each (42%) as Activated B Cell (ABC) or GCB subtypes, while 6 cases resulted unclassified.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Well-designed studies focused on Ruxo-associated infection risk are warranted to correctly evaluate this risk and to define a solid evidence-based infectious prophylactic strategy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Well-de...
PMC10713411	These results suggested that PCD could affect patient prognosis via immunity and metabolism modulation, which also implied that investigations on PCD’s effects on tumor immune microenvironment and metabolism may provide further insights into specific mechanisms of tumor progression and potential molecular biology refer...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	RNA sequencing of suspension and adherent MCL cells was used to identify differentially expressed genes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RNA", "sequencing", "of", "suspension", "and", "adherent", ...
PMC11547972	How amygdalin and SFN interact is not clear.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "How", "amygdalin", "and", "SFN", "interact", "is", "not", "clear", "." ] } ]
PMC11726848	Using flow cytometry, the giant cells were identified by high values of the fsc-a and fsc-h signal relative to the population of the non-irradiated cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10831439	ANOVA, analysis of variance; iNKT, invariant natural killer T. Next, CD19-CAR-iNKT cells were also tested in rechallenge assays to test long-term cytotoxicity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973	Results: As of January 1, 2022, 40 pts (median age 55.5 [range 30-79] years; 72.5% male) had been treated with lisaftoclax (dose range 20-800 mg), including 20 who remain in the trial.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11743316	Since cisplatin-resistant ovarian cancer exhibits overexpression of CRL4, it has been identified as a potential target for ovarian cancer treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Since", "cisplatin-resi...
PMC9812014	Palmatine alkaloid tested against ZIKV in Vero cells which were infected with 400 pfu of Zika virus and then inoculated with varying concentrations of palmatine showed significant repressive activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11711127	Ag and co-stimulatory receptor engagement cause T cells to exit quiescence, permitting clonal proliferation and functional differentiation, both of which are necessary for generating an appropriate immune response (Fig. 2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10495912	Data are expressed as Mean ± Standard deviation (SD) from five independent experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "expressed", "as", "Mean", "±", "Standard", ...
PMC3888431	Non-reference-based transcripts were removed, if an alignment with coverage of at least 95% was found.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Non-reference-based", "transcripts", "were", "removed",...
PMC11306331	Intracellular biomolecular condensates are complex and may involve interactions between many components: co-condensing proteins and RNAs, chaperones that regulate condensate assembly and disassembly, or cooperative interactions between multiple monomers (e.g. to nucleate a new condensate), and we reasoned that OptoMBP-...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9910796	As shown in S2 Fig, pEP84R displayed a predominantly perinuclear pattern, which significantly colocalized with membrane markers for ER-Golgi intermediate compartment (ERGIC-53), cis-Golgi (GM130) and trans-Golgi network (TGN46), along with a weaker cytoplasmic reticular-like pattern emerging from the nuclear envelope, ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11792766	No. D4551), tetrahydrofuran (THF) (Sigma Aldrich, Cat.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No.", "D4551", ")", ",", "tetrahydrofuran", "(", "THF", ")", "(", ...
PMC11394227	Additionally, it has been shown to inhibit apoptosis induced by Fas, Bax, and anticancer drugs, indicating a broad range of anti-apoptotic capabilities .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11726183	It revealed the importance of substitution at the ortho position, which is favorable for inhibiting breast cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "revealed", "the", "importan...
PMC8540611	In the case of AuNP13, the optimal delivery concentrations were quite high and can themselves cause serious toxicity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "case", "of", "...
PMC9429973	For the 31% of patients that had a PC drop following D1, there was an increased probability of a PC drop with D2, however for more than half of those patients the degree of PC drop was not greater with D2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10850553	U-937 cell line was differentiated into macrophage-like cells by culturing with 10 μM Phorbol 12-myristate 13-acetate (PMA, lot: WDH4676, #162-23591, FUJIFILM Wako Pure Chemical Corporation) for 48 h. NIH3T3 cells were treated with each dose of the selective mTOR (mammalian target of rapamycin) inhibitor Torin1 (IC50; ...	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11727306	In addition, strains of S. aureus that were isolated from atopic dermatitis patients were found to produce SEA , and high titers of anti-SEA antibody have been documented in several Atopic dermatitis patients .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8567602	supernatant.	[ { "tags": [ "O", "O" ], "tokens": [ "supernatant", "." ] } ]
PMC9429973	K. Rankin, B. Beaton, S. Sasson, J. Raedemaecker, A. Wong, P. Hastak, C. Phetsouphanh, A. Warden, M. Patel, V. Klemm, C. M. L. Munier, A. Carey Hoppe, F. Tea, A. Pillay, A. Ospina, A. Aggarwal, O. Lavee, I. D. Caterson, S. Turville, A. D. Kelleher, F. Brilot, J. Trotman Haematology Department, Calvary Mater Hospital Ne...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11683130	However, whether SerpinB3 is participating in the pathogenesis of psoriasis by itself or by hydrolyzing into Pso p27 has not been investigated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However...
PMC11740508	Mean ± SD were calculated for the SRB endpoint assays, cell cycle assays, and cell death assays.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mean", "±", "SD", "were", "...
PMC11462673	confirm that MYB overexpression is a dependency factor and therapeutic target in T-cell leukemia .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "confirm", "that", "MYB", "overexpression", "is", "a", "dependency", ...
PMC10993311	Excess weight is associated with changes in inflammatory parameters, blood glucose, triglycerides, and lipids (Gulecoglu Onem et al., 2021; Rugină et al., 2021).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6182045	A 106-day study designed to determine cell line stability and viability over time was carried out.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "106-day", "study", "designed", "to", "determine",...
PMC11683130	SerpinB3/B4 are taken up by mast cells to form Pso p27 through cleavage of chymoenzymes in mast cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SerpinB3/B4", "are", "taken", "up", "b...
PMC11786767	Accordingly, we postulate that Ki-67 and nuclear lipids may act in concert during mitosis to segregate or individualize the various sister chromatid pairs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9503685	CSA-13 has been shown to inhibit bacterial adhesion at sub-MIC concentrations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CSA-13", "has", "been", "shown", "to", "inhibit", "bacterial", "adhesion", "at", "sub...
PMC11470999	Seven days later, treatments with PF (15 mg/kg) and temozolomide (TMZ) (40 mg/kg) were administered twice a week. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11349530	For instance, IL-6 signaling is involved in immunotherapy resistance (45, 99).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "instance", ",", "IL-6", "signaling", "is", "involved...
PMC11478724	In the A549 cell line, after 24 h of treatment, the percentage of late apoptotic cells was found to be 14.4%, which remained constant at 48 h. The percentage of necrosis cells was found to be 1.24%, and 28.5% after 24 and 48 h, respectively.	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11467964	Differences in the expression of BMRGs among the two gene subtypes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Differences", "in", "the", "expression", "of", "BMRGs", "among", "the", "two", "gene"...
PMC11541241	Thus, TOR kinase is reported to play an important role in F. oxysporum autophagy regulation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", "TOR", "kinase", "is", "reported", "...
PMC11323699	Gain of 20% body weight was considered as the end point for survival analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Gain", "of", "20", "%", "body", "weight", "was", "con...
PMC11615218	Additionally, higher levels of tonic signaling resulting from self-aggregation of CARs have been reported to cause CAR-T cell exhaustion .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "higher"...
PMC10578720	The chronic HBV infection process involves complex interactions between viruses and the host immune system.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "chronic", "HBV", "infection", "process", "involves", ...
PMC9872547	The prepared nano-curcumin was stored at 4°C and away from light (7, 8).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "prepared", "nano-curcumin", "was", "stored...
PMC9429973	No incidences of serious AEs were reported in PADDOCK and PRINCE subgroups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "incidences", "of", "serious", "AEs", "were", "reported", "in", "PADDOCK", ...
PMC11638255	BioRender.com/j88j488.	[ { "tags": [ "O", "O" ], "tokens": [ "BioRender.com/j88j488", "." ] } ]
PMC11489175	Following the histidine polarization, the pKa of the cysteine is lowered and this feature induces thiol deprotonation and thiolate stabilization 26, 24.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10813895	Understanding these age-related molecular and cellular changes is vital for linking aging biology with BC biology and elucidating how aging make breast tissue susceptible to BC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11290772	Adding to the gravity of the situation, the 5-year survival rate for ovarian cancer patients stands at a mere 47% .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Adding", "to...
PMC9429973	Ospedale Santa Maria delle Croci, Hematology Unit, Ravenna; Department of Translational Medicine, University of Eastern Piedmont, Division of Hematology, Novara; Centro trapianti e terapie cellulari, Clinica ematologica, Ospedale Santa Maria della Misericordia- ASUFC, Udine; Ospedale Oncologico Armando Businco, Divisio...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11063646	At the end of the incubation period, the medium was removed from all wells, and a PBS wash was given.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "the", ...
PMC7348793	This is consistent with the documented derivation of the COS-7 cell line from Cercopithecus aethiops .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "is", "consistent", "with", "the", "documented", ...
PMC11519567	The oncogenic fusion protein SS18-SSX is significantly different from the proto-oncoprotein SS18 in four aspects: First, the number of SS18-SSX protein condensates is significantly increased; second, SS18-SSX condensate is more resistant to 1,6-Hex; third, the two types of condensates present distinct molecular dynamic...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11247842	The lead SNPs on BTA1 for MTAG_SCS were BTA1: 131,508,931 (rs133645774) and BTA1: 145,932,212 (rs469947398).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "lead", "SN...
PMC11138140	A 1000X 10 mM stock of norepinephrine was prepared fresh prior to each experiment and was dissolved directly in the serum-free culture medium.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", ...
PMC11240448	A description of the model derivation and parameter estimation is given in Section 2 (see Section 2.4, Section 2.5 and Section 2.6).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11394730	The initial step in the PPP is catalyzed by glucose-6-phosphate-dehydrogenase (G6PDH), an essential enzyme that controls the rate at which tumor cells grow.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC7504302	Recurrent somatic copy number gains are less common in MPM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Recurrent", "somatic", "copy", "number", "gains", "are", "less", "common", "in", "MPM", "....
PMC9581083	Famous TCM formulas include Qing-Fei-Pai-Du-Tang (QFPDT), Lianhuaqingwen Capsule (LHC), Taiwan Chingguan Yihau (NRICM101), and Jing Si herbal drink (JSHD).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10748106	The CaLo and INBL cell lines were donated by Profesor María de Lourdes Gutiérrez Xicoténcatl from Centro de Investigación sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública.	[ { "tags": [ "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11486946	Then, the medium was replaced with 10 μL of Cell Counting Kit −8 (Dojindo, Japan) diluted in 100 μL HBSS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9952933	However, our in vitro study indicates that the non-malignant HOB shows lower susceptibility to CAP treatments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "our", "in", "vitro", "study...
PMC10506676	To the best of our knowledge, for the first time, we showed that the expression of EBNA1 can lead to significant morphological changes in HeLa cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellL...
PMC11478724	Complementary DNA (cDNA) was syntheses using cDNA Synthesis Kit (addbio-Korea).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Complementary", "DNA", "(", "cDNA", ")", "was", "syntheses", "us...
PMC8143558	Fifty-three (53) publications were removed because the 40 mg/g saponin threshold was not met.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fifty-three", "(", "53", ")", "publications", "were", ...
PMC11583690	At each time point, the amount of DTX released into the solution was quantified using HPLC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "each", "time", "point", ",", "the", ...
PMC11306331	n = 148 cells pooled from three biological replicates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "n", "=", "148", "cells", "pooled", "from", "three", "biological", "replicates", "." ] } ]
PMC11470999	These may be the mechanism by which PF promotes CIP2A ubiquitination and degradation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "may", "be", "the", "mechanism", "by", "which", "PF", "promot...
PMC11767582	HRMS (ESI/Q-TOF): m/z [M+H] calcd.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HRMS", "(", "ESI/Q-TOF", "):", "m/z", "[", "M+H", "]", "calcd", "." ] } ]
PMC9596868	The data was analyzed using BD FACSDiva (Becton Dickinson, NJ, USA) software.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "data", "was", "analyzed", "using", "BD", ...
PMC11519788	Consistent with the impact of STAT3 knockdown, treatment of UBC cells with Stattic, a specific small molecule inhibitor targeting STAT3, similarly inhibited cell proliferation and sphere formation (Figure S3D-E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11656048	All of the in vitro experiments were performed at least three times.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "of", "the", "in", "vitro", "experiments", "were", "performed", "at", ...
PMC11413393	An MS023 dose-dependent reduction in levels of BUB1B, CENPA and CENPI was detected after three days of treatment (Fig. 5a) and immunoblotting with Anti-H3S10p in RCC243 following 3, 5 and 7 days of 5 µM MS023 exposure confirmed a decline in the relative cell population actively undergoing mitosis relative to controls (...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11672881	Our data reveal that the combination of CU and TQ exhibited synergistic cytotoxicity against A375 cells in the 3D spheroid model and 2D.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC8557138	Hence, developing 3D multicellular tumor vascular models consisting of neurons would unravel the role of these neurotransmitters in the tumoral arena.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hence", ",",...
PMC11098378	Image was created with BioRender.com.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Image", "was", "created", "with", "BioRender.com", "." ] } ]

PMC9817179

Confocal fluorescence microscopy was performed on Zeiss LSM 980 in the point-scanning mode with a ×63 oil objective (Zeiss, 421782-9900-000).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC5833712

Moreover, we have shown that KB9520-activated ERβ has a strong stimulatory effect on KDM6B expression, that most likely add to the ERβ-mediated ovarian tumor inhibitory activity.

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PMC11286266

S–S indicates for the disulphide bond in the LD between two cysteines. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "S", "–", "S", "indicates", "for", "the", "disulphide", ...

PMC9429973

During cycle 3, 5.3% showed anemia ≥grade 3, 10.5% showed thrombocytopenia ≥grade 3, while 15.8% showed lymphopenia ≥grade 3.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC11543935

The electrode mounting interface developed in this study combines these requirements by ensuring a reliable electrode placement while being able to adjust the electrode distance and having an access point for the temperature sensor.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11739504

SDCCAG3 has also been reported to localize to the basal body and interact with IFT88.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SDCCAG3", "has", "also", "been", "reported", "to", "localiz...

PMC11411131

Cos-7 cells transiently expressing Krab-Sec/Luc were treated with 20 µM MeHg for 24 h (Fig. 6A).

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PMC11413393

An MS1 ion scan was performed at 60,000 FWHM followed by MS/MS scans (HCD, 15,000 fwhm) of up to 20 parent ions (minimum activation of 1000).

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PMC11680562

While the plain gel showed no inhibition, the CuO NPs displayed significant inhibition (22.35 ± 49 mm), and the PXFCu6 gel exhibited the largest zone (52.05 ± 1.37 mm), demonstrating the superior antibacterial activity, indicating that it may protect the vagina and lower the risk of infections like aerobic vaginitis an...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11641532

Principal components were selected based on the following criteria: cumulative contribution >90%, individual component variance contribution <5%, and the difference between two consecutive components <0.1%.

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PMC11792766

Differences were considered to be statistically significant when *p < 0.05; **p < 0.01; ***p < 0.001.

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PMC9429973

Image: Summary/Conclusion: This real-life study demonstrated an improved outcome among FLT3mut AML patients treated in the most recent period, probably reflecting the beneficial effect of midostaurin on relapse prevention in this context.

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PMC11323699

ovarian carcinoma cells injected either subcutaneously (SC) or intraperitoneally (IP).

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PMC11721587

The remaining pellet was extracted with 10 mM tris-HCl (pH 7.5), 300 mM NaCl, and 1% NP 40 to yield nuclear fraction.

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PMC11701801

Ten percent of lung cancer and most of small cell carcinoma of the ovary, hypercalcemic type (SCCOHT), are deficient in both SMARCA4 and SMARCA2 (10, 11).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC5600151

MVP overexpression in cancer cells is involved in transporting drugs away from the nucleus, and is thus related to multidrug resistance.

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PMC11588085

Then, an mRNA stemness index is calculated for each subgroup of tumors belonging to the first quartile (high) and the last quartile (low) of XIST expression.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Corticosteroid prophylaxis and step-up dosing of epcoritamab were required in cycle 1 to mitigate CRS.

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PMC11718109

Scale bar, 500 nm.

[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", ",", "500", "nm", "." ] } ]

PMC10387886

Immunoreactive bands were visualized by using chemiluminescence (Luminata Forte HRP Substrate, Millipore) in ChemiDoc™ MP Imaging System (Bio-Rad).

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PMC9429973

Results: The platelet aggregation was tested in 69 patients with MPN on ASA.

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PMC11718031

Subsequently, cells are passaged in the same basal medium or a combination of the basal medium and a feed to adapt the cells for bioreactor cultivation.

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PMC11656657

At the endpoint the percentage of residual tumor was evaluated by FACS as measure of GFP tumor expression.

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PMC11298021

The present study aimed to investigate the potential cytotoxic effects of rapamycin and PI3K/AKT/mTOR inhibitory miRNAs, alone or in combination, against NOTCH1-driven T-ALL.

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PMC8143558

The results for E. camaldulensis Dehnh also confirm variations in the saponin content when different solvents are used to extract the same part of the plant.

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PMC11737091

Another study conducted by Zhang et al. demonstrated that DBF4 promotes STAT3 signaling activation in hepatocellular carcinoma cells via a CDC7-mediated and XPO1-dependent mechanism .

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PMC11604830

The squares pictured in the image correspond to the voxels acquired by PRESS: Black, PLN of the left leg; red, PLN of the right leg (tumor‐bearing side); orange, pure low‐gelling agar; yellow, PFCE‐NE in low‐gelling agar (0.66 M proton concentration).

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PMC9429973

Lymph2Cx-based assay was successful in 38 cases and classified 16 cases each (42%) as Activated B Cell (ABC) or GCB subtypes, while 6 cases resulted unclassified.

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PMC9429973

Well-designed studies focused on Ruxo-associated infection risk are warranted to correctly evaluate this risk and to define a solid evidence-based infectious prophylactic strategy.

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PMC10713411

These results suggested that PCD could affect patient prognosis via immunity and metabolism modulation, which also implied that investigations on PCD’s effects on tumor immune microenvironment and metabolism may provide further insights into specific mechanisms of tumor progression and potential molecular biology refer...

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PMC9429973

RNA sequencing of suspension and adherent MCL cells was used to identify differentially expressed genes.

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PMC11547972

How amygdalin and SFN interact is not clear.

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PMC11726848

Using flow cytometry, the giant cells were identified by high values of the fsc-a and fsc-h signal relative to the population of the non-irradiated cells.

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PMC10831439

ANOVA, analysis of variance; iNKT, invariant natural killer T. Next, CD19-CAR-iNKT cells were also tested in rechallenge assays to test long-term cytotoxicity.

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PMC9429973

Results: As of January 1, 2022, 40 pts (median age 55.5 [range 30-79] years; 72.5% male) had been treated with lisaftoclax (dose range 20-800 mg), including 20 who remain in the trial.

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PMC11743316

Since cisplatin-resistant ovarian cancer exhibits overexpression of CRL4, it has been identified as a potential target for ovarian cancer treatment.

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PMC9812014

Palmatine alkaloid tested against ZIKV in Vero cells which were infected with 400 pfu of Zika virus and then inoculated with varying concentrations of palmatine showed significant repressive activity.

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PMC11711127

Ag and co-stimulatory receptor engagement cause T cells to exit quiescence, permitting clonal proliferation and functional differentiation, both of which are necessary for generating an appropriate immune response (Fig. 2).

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PMC10495912

Data are expressed as Mean ± Standard deviation (SD) from five independent experiments.

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PMC3888431

Non-reference-based transcripts were removed, if an alignment with coverage of at least 95% was found.

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PMC11306331

Intracellular biomolecular condensates are complex and may involve interactions between many components: co-condensing proteins and RNAs, chaperones that regulate condensate assembly and disassembly, or cooperative interactions between multiple monomers (e.g. to nucleate a new condensate), and we reasoned that OptoMBP-...

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PMC9910796

As shown in S2 Fig, pEP84R displayed a predominantly perinuclear pattern, which significantly colocalized with membrane markers for ER-Golgi intermediate compartment (ERGIC-53), cis-Golgi (GM130) and trans-Golgi network (TGN46), along with a weaker cytoplasmic reticular-like pattern emerging from the nuclear envelope, ...

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PMC11792766

No. D4551), tetrahydrofuran (THF) (Sigma Aldrich, Cat.

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PMC11394227

Additionally, it has been shown to inhibit apoptosis induced by Fas, Bax, and anticancer drugs, indicating a broad range of anti-apoptotic capabilities .

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PMC11726183

It revealed the importance of substitution at the ortho position, which is favorable for inhibiting breast cancer cells.

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PMC8540611

In the case of AuNP13, the optimal delivery concentrations were quite high and can themselves cause serious toxicity.

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PMC9429973

For the 31% of patients that had a PC drop following D1, there was an increased probability of a PC drop with D2, however for more than half of those patients the degree of PC drop was not greater with D2.

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PMC10850553

U-937 cell line was differentiated into macrophage-like cells by culturing with 10 μM Phorbol 12-myristate 13-acetate (PMA, lot: WDH4676, #162-23591, FUJIFILM Wako Pure Chemical Corporation) for 48 h. NIH3T3 cells were treated with each dose of the selective mTOR (mammalian target of rapamycin) inhibitor Torin1 (IC50; ...

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PMC11727306

In addition, strains of S. aureus that were isolated from atopic dermatitis patients were found to produce SEA , and high titers of anti-SEA antibody have been documented in several Atopic dermatitis patients .

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PMC8567602

supernatant.

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PMC9429973

K. Rankin, B. Beaton, S. Sasson, J. Raedemaecker, A. Wong, P. Hastak, C. Phetsouphanh, A. Warden, M. Patel, V. Klemm, C. M. L. Munier, A. Carey Hoppe, F. Tea, A. Pillay, A. Ospina, A. Aggarwal, O. Lavee, I. D. Caterson, S. Turville, A. D. Kelleher, F. Brilot, J. Trotman Haematology Department, Calvary Mater Hospital Ne...

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PMC11683130

However, whether SerpinB3 is participating in the pathogenesis of psoriasis by itself or by hydrolyzing into Pso p27 has not been investigated.

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PMC11740508

Mean ± SD were calculated for the SRB endpoint assays, cell cycle assays, and cell death assays.

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PMC11462673

confirm that MYB overexpression is a dependency factor and therapeutic target in T-cell leukemia .

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PMC10993311

Excess weight is associated with changes in inflammatory parameters, blood glucose, triglycerides, and lipids (Gulecoglu Onem et al., 2021; Rugină et al., 2021).

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PMC6182045

A 106-day study designed to determine cell line stability and viability over time was carried out.

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PMC11683130

SerpinB3/B4 are taken up by mast cells to form Pso p27 through cleavage of chymoenzymes in mast cells.

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PMC11786767

Accordingly, we postulate that Ki-67 and nuclear lipids may act in concert during mitosis to segregate or individualize the various sister chromatid pairs.

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PMC9503685

CSA-13 has been shown to inhibit bacterial adhesion at sub-MIC concentrations.

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PMC11470999

Seven days later, treatments with PF (15 mg/kg) and temozolomide (TMZ) (40 mg/kg) were administered twice a week. (

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PMC11349530

For instance, IL-6 signaling is involved in immunotherapy resistance (45, 99).

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PMC11478724

In the A549 cell line, after 24 h of treatment, the percentage of late apoptotic cells was found to be 14.4%, which remained constant at 48 h. The percentage of necrosis cells was found to be 1.24%, and 28.5% after 24 and 48 h, respectively.

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PMC11467964

Differences in the expression of BMRGs among the two gene subtypes.

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PMC11541241

Thus, TOR kinase is reported to play an important role in F. oxysporum autophagy regulation.

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PMC11323699

Gain of 20% body weight was considered as the end point for survival analysis.

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PMC11615218

Additionally, higher levels of tonic signaling resulting from self-aggregation of CARs have been reported to cause CAR-T cell exhaustion .

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PMC10578720

The chronic HBV infection process involves complex interactions between viruses and the host immune system.

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PMC9872547

The prepared nano-curcumin was stored at 4°C and away from light (7, 8).

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PMC9429973

No incidences of serious AEs were reported in PADDOCK and PRINCE subgroups.

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PMC11638255

BioRender.com/j88j488.

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PMC11489175

Following the histidine polarization, the pKa of the cysteine is lowered and this feature induces thiol deprotonation and thiolate stabilization 26, 24.

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PMC10813895

Understanding these age-related molecular and cellular changes is vital for linking aging biology with BC biology and elucidating how aging make breast tissue susceptible to BC.

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PMC11290772

Adding to the gravity of the situation, the 5-year survival rate for ovarian cancer patients stands at a mere 47% .

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PMC9429973

Ospedale Santa Maria delle Croci, Hematology Unit, Ravenna; Department of Translational Medicine, University of Eastern Piedmont, Division of Hematology, Novara; Centro trapianti e terapie cellulari, Clinica ematologica, Ospedale Santa Maria della Misericordia- ASUFC, Udine; Ospedale Oncologico Armando Businco, Divisio...

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PMC11063646

At the end of the incubation period, the medium was removed from all wells, and a PBS wash was given.

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PMC7348793

This is consistent with the documented derivation of the COS-7 cell line from Cercopithecus aethiops .

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PMC11519567

The oncogenic fusion protein SS18-SSX is significantly different from the proto-oncoprotein SS18 in four aspects: First, the number of SS18-SSX protein condensates is significantly increased; second, SS18-SSX condensate is more resistant to 1,6-Hex; third, the two types of condensates present distinct molecular dynamic...

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PMC11247842

The lead SNPs on BTA1 for MTAG_SCS were BTA1: 131,508,931 (rs133645774) and BTA1: 145,932,212 (rs469947398).

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PMC11138140

A 1000X 10 mM stock of norepinephrine was prepared fresh prior to each experiment and was dissolved directly in the serum-free culture medium.

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PMC11240448

A description of the model derivation and parameter estimation is given in Section 2 (see Section 2.4, Section 2.5 and Section 2.6).

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PMC11394730

The initial step in the PPP is catalyzed by glucose-6-phosphate-dehydrogenase (G6PDH), an essential enzyme that controls the rate at which tumor cells grow.

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PMC7504302

Recurrent somatic copy number gains are less common in MPM.

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PMC9581083

Famous TCM formulas include Qing-Fei-Pai-Du-Tang (QFPDT), Lianhuaqingwen Capsule (LHC), Taiwan Chingguan Yihau (NRICM101), and Jing Si herbal drink (JSHD).

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PMC10748106

The CaLo and INBL cell lines were donated by Profesor María de Lourdes Gutiérrez Xicoténcatl from Centro de Investigación sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública.

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PMC11486946

Then, the medium was replaced with 10 μL of Cell Counting Kit −8 (Dojindo, Japan) diluted in 100 μL HBSS.

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PMC9952933

However, our in vitro study indicates that the non-malignant HOB shows lower susceptibility to CAP treatments.

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PMC10506676

To the best of our knowledge, for the first time, we showed that the expression of EBNA1 can lead to significant morphological changes in HeLa cells.

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PMC11478724

Complementary DNA (cDNA) was syntheses using cDNA Synthesis Kit (addbio-Korea).

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PMC8143558

Fifty-three (53) publications were removed because the 40 mg/g saponin threshold was not met.

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PMC11583690

At each time point, the amount of DTX released into the solution was quantified using HPLC.

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PMC11306331

n = 148 cells pooled from three biological replicates.

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PMC11470999

These may be the mechanism by which PF promotes CIP2A ubiquitination and degradation.

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PMC11767582

HRMS (ESI/Q-TOF): m/z [M+H] calcd.

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PMC9596868

The data was analyzed using BD FACSDiva (Becton Dickinson, NJ, USA) software.

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PMC11519788

Consistent with the impact of STAT3 knockdown, treatment of UBC cells with Stattic, a specific small molecule inhibitor targeting STAT3, similarly inhibited cell proliferation and sphere formation (Figure S3D-E).

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PMC11656048

All of the in vitro experiments were performed at least three times.

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PMC11413393

An MS023 dose-dependent reduction in levels of BUB1B, CENPA and CENPI was detected after three days of treatment (Fig. 5a) and immunoblotting with Anti-H3S10p in RCC243 following 3, 5 and 7 days of 5 µM MS023 exposure confirmed a decline in the relative cell population actively undergoing mitosis relative to controls (...

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PMC11672881

Our data reveal that the combination of CU and TQ exhibited synergistic cytotoxicity against A375 cells in the 3D spheroid model and 2D.

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PMC8557138

Hence, developing 3D multicellular tumor vascular models consisting of neurons would unravel the role of these neurotransmitters in the tumoral arena.

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PMC11098378

Image was created with BioRender.com.

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