OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11361748	Pretreatment with Gö6976 prior to UVB Tx in TPA-primed skin resulted in a significant reduction of neutrophil dermal infiltration (S4D Fig).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Pretrea...
PMC4395774	Mouse primary NK cells were isolated from spleens of prf mice using CD49b (DX5) microbeads (Miltenyi Biotec, Woking, UK) following the manufacturer instructions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7887261	II (# SL100489, SignaGen).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "II", "(", "#", "SL100489", ",", "SignaGen", ")", "." ] } ]
PMC11787355	In c, e–h, and j, N(biological)=4.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "c", ",", "e", "–", "h", ",", "and", "j", ",", "N(biological)=4", "....
PMC11621493	The base-exchange was verified by Sanger sequencing.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "base-exchange", "was", "verified", "by", "Sanger", "sequencing", "." ] } ]
PMC11790971	This qualitative inspection provided by these visualizations serves as an initial step in identifying cell line differences.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "qualitative", "inspection", "provided", "...
PMC10882807	Cell proliferation ability was assessed by colony formation assays after HCCLM3 cells transfected with shNC + vector, shEIF4A3 + pcDNA or shEIF4A3 + pcDNA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC11676169	For analyses comparing multiple experimental groups, the Kruskal–Wallis test (non-parametric test) was used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "analyses", "comparing", "multiple", ...
PMC11694066	Our work specifically underlines the translational potential of combining PARPi and ATRi in DSRCT, a combination that is currently being evaluated by multiple clinical trials, including in children (NCT02813135).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The cut-off point of ≥10 identifies probable cases of GAD that may require further psychiatric assessment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cut-off", "point", "of", "≥10", "identifies", ...
PMC10297204	At 0% ethanol concentration, the cells passed through the invasion chamber were stained with crystal violet.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "0", "%", "ethanol", "concentrati...
PMC11678368	The new complex, trans-[PtCl2(7AI3CA)2], exhibited cytotoxicity similar to that of cisplatin in LoVo (colon cancer) and MCF7 (breast cancer) cell lines, while its cytotoxicity was significantly lower in A549 (lung cancer) compared to cisplatin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "...
PMC11502066	For covering all the subject, a systematic search for articles was performed by the words “flavonoid” and “cancer” and all individual members of GPCRs listed in the IUPHAR/BPS Guide to Pharmacology (excluding those belonging to the subclass of orphan and other 7TM receptors) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11087766	The stalled intermediate colocalized with fluorescently tagged PicA foci on the nuclear periphery, suggesting a two-step import model in which proteins are first targeted to PicA and then licensed to be translocated across the nuclear shell by the import machinery (Fig. 5A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11627398	Huo et al. found that advanced glycosylation end products could trigger cuproptosis in cardiomyocytes through upregulating SLC31A1 , suggesting that SLC31A1 may exert a pro-cuproptosis role.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11544122	This is exemplified by SNX27, which has been shown to be required for the recycling of several GPCRs, including β2AR, parathyroid hormone receptor (PTHR), and 5-hydroxytryptamine 4A receptor (5-HT4AR).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11590005	The Modern Racism Scale (MRS) was developed to measure the cognitive component of subtle racial attitudes using a less reactive approach .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC11730305	The specific focus of this study is to investigate the anticancer potential of cobalt oxide nanoparticles (Co3O4) functionalized with glucose and conjugated with EA (Co3O4@Glu-Ellagic acid) in human liver cancer cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Results: After exclusion, 234 COVID-19 and 58 MERS-COV patients were included.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "After", "exclusion", ",", "234", "COVID-19", "and", "...
PMC6160470	As a model for studying MDR related to overexpression of P-gp, we used ovarian carcinoma cell line A2780 and its adriamycin (doxorubicin) resistant counterpart A2780/Adr.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", ...
PMC11761919	On day 5 dpi, sera were collected to detect inflammatory factors and enzymes, and liver tissues were sampled to quantify viral load.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11706776	In conclusion, our results have demonstrated the overexpression of KCNN1 in ES patients, identifying KCNN1 as a novel potential therapeutic target in this tumor.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10788478	Tumor cells with nuclear or cytoplasmic staining were defined as positive.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tumor", "cells", "with", "nuclear", "or", "cytoplasmic", "staining", "were", "defined", ...
PMC7823217	Various 3D bioprinting approaches have been used to develop biomimetic liver tissue constructs that can recapitulate native liver tissue microenvironment, vasculature and precise spatiotemporal signaling .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11371627	However, patients with pathogenic variants in exon 3 and in close proximity to the novel deletion of our patient (c.756del, p.Trp253Glyfs*15) did manifest with neuropathy and myopathy, frequently displaying areflexia, elevated CK and acanthocytosis without hepatopathy or cardiomyopathy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11106977	Through this mechanism, OGT modulates almost every biological process that occurs within the cell.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Through", "this", "mechanism", ",", "OGT", "modulates", "al...
PMC6163708	NSCLC lung cancer cell lines A549, HT1299, A-427, Calu-1, H-460, H-520, H596, H-661, H-2170, and SK-MES-1, and SCLC cell lines H-446, H-69, H-209, H-82, H-345, H-146, H-378, H-196 were purchased from ATCC.	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O...
PMC11545737	On the other hand, several pathogens have developed strategies to overcome or disrupt these barriers to gain access and invade host tissues.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "On", ...
PMC9895440	Hs.eg.db_3.15.0, TxDb.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "Hs.eg.db_3.15.0", ",", "TxDb", "." ] } ]
PMC11707577	Data analysis was performed with CytExpert (Beckam Coulter) and FlowJo™.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "analysis", "was", "performed", "with", "CytExpert", "(", "Beckam", ...
PMC6617630	Data represent mean ± SD from three independent experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "represent", "mean", "±", "SD", "from", "three", "independent", "experiments", "." ] } ]
PMC9429973	Thirty-one patients (84%) died during the induction cure with a median time between the start of the cure and death of 17 days [2-29].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11665555	Pathway enrichment analysis between untreated parental and 5637GR showed pyrimidine metabolism as among one of the significantly altered pathways in the development of gemcitabine resistance (Figure 4B and Supplemental Table 2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10604092	We observed that SLC-transplanted rats exhibited severe anorexia, weight loss, muscle atrophy, and weakness.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "observed", "that", "SLC-transplanted", "rat...
PMC11377827	Immunoblot of the soluble (S) and chromatin fractions (Ch) obtained using a formaldehyde crosslinking chromatin extraction protocol.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Immunoblot", "of", ...
PMC10178190	It is of interest to translate our in vitro results to validation in pre-clinical and clinical settings toward improving cancer therapy in ovarian cancer patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11155445	Similarly, the enhanced activity of benzene complexes of Ru as compared to p-cymene, was due to the presence of methyl and isopropyl groups on p-cymene which hindered the adduct formation (Fig. 17).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9516447	The quantitation of the relative KRAS protein level after normalization to GADPH levels is shown in the graphs below. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "quantitation", "of", ...
PMC10568263	The aqueous solutions of 30 μL MoO3 and 30 μL Au@MnO2 were dropped onto screen-printed electrodes (SPEs), respectively, and dried at 60 °C for 30 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8348645	1 × 10 cells) of treated and untreated cells were taken separately in a microcentrifuge tube and stained with 5 µL of AO-EtBr (acridine orange and ethidium bromide) for about 2 min followed by gentle mixing.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11467964	Kaplan–Meier survival curves demonstrated that the patients in the high‐risk group had a poor prognosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Kaplan", "–", "Meier", "survival", "curves", ...
PMC11394730	2-phenylchromenylium, also known as flavylium, is the basic structure of anthocyanin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "2-phenylchromenylium", ",", "also", "known", "as", "flavylium", ",", "is", ...
PMC8996378	Studies have shown that the expression of ABCB1 is regulated by various signaling pathways, such as nuclear factor κB (NF-κB) (Sun et al., 2012), mitogen-activated protein kinases (MAPK) (Luo et al., 2016) and phosphoinositide-3-kinase–protein kinase B (PI3K-PKB) (Dong et al., 2017).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11590005	Different letters indicate statistically significant difference.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Different", "letters", "indicate", "statistically", "significant", "difference", "." ] } ]
PMC9424261	Interestingly, the same number of cell death or lipid ROS were produced in HERPUD1-sg1 cells when erastin or RSL3 were added after 1 h of CA pretreatment compared to wild-type liver cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11055510	FISH assay detected the localization of circMAN1A2 in cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "FISH", "assay", "detected", "the", "localization", "of", "circMAN1A2", "in", "cells", "." ] } ]
PMC9429973	Participants’ ages ranged from 35 to 84 years (Median = 61).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Participants", "’", "ages", "ranged", "from", "35", "to", "84", ...
PMC9250505	Tissue was minced with scissors (except for AFC cells), and the tissue fragments or AFC cells were incubated in serum-free Advanced Dulbecco’s modified Eagle’s medium (DMEM)/F12 (Thermo Fisher Scientific, Inc., Waltham, MA, USA) containing 1.5 mg/ml collagenase IV (Gibco; Thermo Fisher Scientific, Inc.) and 1% penicill...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7823217	An interesting study indicated that tuning of rheological properties of sodium alginate-gelatin hydrogel improves the printability and viability of non-small cell lung cancer patient derived xenograft cells and cancer associated fibroblasts co-cultures, allowing for 3D spheroid development within the printed construct ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9454852	For this reason, a confocal time-lapse analysis was performed to evaluate the [Ca]i variation induced by BOLD-100.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "this", "reason", ",", "a", ...
PMC9429973	Expression of protein coding genes (PCGs), lncRNAs and circRNAs was bioinformatically processed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Expression", "of", "protein", "coding", "genes", "(", "PCGs...
PMC11705484	Finally, we identified TRMT61A inhibitors using a virtual screening strategy and two compounds (abbreviated as CMP) were potentially effective in inhibiting TRMT61A (Figure 4A,B, Figures S6–S8 and Table S1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11489351	However, despite being associated with these pH-dependent behaviors, Notch1 expression and activity have not been previously shown to be pH-sensitive.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",...
PMC11695623	GO functional annotation showed that the related genes were mainly enriched in chromosome segregation, chromosomal region and ATP-dependent activity, acting on DNA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11155445	Huang et al. synthesized polyvinylidene fluoride (PVDF)/N-benzoyl-N′,N′-dibutyl thiourea (170) composite membrane for Ag adsorption by mixing PVDF and (170) in DMF.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11204465	AFB2a (75) was discovered while testing the ability of various microbes to detoxify AFB1 .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "AFB2a", "(", "75", ")", "was", "discovered", "wh...
PMC11746942	G Western blot analysis of P-STAT3 (Y705), STAT3, P-AKT (S473), P-AKT (T308), AKT, S1PR3, S1PR2, K16, Survivin, and GAPDH protein levels in HaCaT cells stimulated with IL-6 or IL-22 in the presence or absence of FTY720 pretreatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	F. Peci, J. de Kanter, N. Groenen, A. Rosendahl-Huber, L. Derks, E. Bertrums, S. Middelkamp, M. J. van Roosmalen, R. van Boxtel Princess Máxima Center for Pediatric Oncology, Utrecht, Netherlands Background: Nucleoside analog (NAs) drugs are used for the treatment of a variety of diseases, such as cancers and viral inf...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11637276	NMuMG, PyMT#1, and YEJ P cells were a gift from Professor Jim Norman (CRUK Scotland Institute, Glasgow, United Kingdom).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11519583	To examine Wnt5a and Wnt5b function in MPs, we treated MPs with Wnt5a siRNAs or Wnt5b siRNAs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "examine", "Wnt5a", "and", "Wnt5b...
PMC11252033	Ovarian cancer is the deadliest gynaecologic malignancies worldwide.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ovarian", "cancer", "is", "the", "deadliest", "gynaecologic", "malignancies", "worldwide", "." ] } ]
PMC11656657	No tumor bearing mice have been used as control group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "tumor", "bearing", "mice", "have", "been", "used", "as", "control", "group", "." ...
PMC11463018	H NMR (500 MHz, DMSO-d6) δ: 11.16 (s, 1H), 8.97 (s, 1H), 8.03 − 7.98 (m, 2H), 7.72 − 7.68 (m, 2H), 7.54 − 7.49 (m, 1H), 7.44 − 7.31 (m, 6H), 7.08 − 7.04 (m, 1H), 4.46 (d, J = 6.3 Hz, 2H).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9096373	There were no significant differences in tumor volume between the APA + RT and DDPs + RT groups (only reduced by 5.3%; t=1.97, P>0.05).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9352806	300 μL of supernatant was transferred to a fresh tube and dried in a vacuum concentrator at 37 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "300", "μL", "of", "sup...
PMC11011837	In order to obtain better results and minimize variations, cells from all four cell lines were seeded at the same concentration and, after 48 h, were harvested, counted, and collected into a pellet via centrifugation at 300× g, washed twice with phosphate-buffered saline (PBS), and stored at −80 °C until LC/MS analysis...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6487404	Monolayers displaying TEER values greater than 300 Ωcm were used for transport studies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Monolayers", "displaying", "TEER", "values", "greater", "than", "300", "Ωcm...
PMC11745823	ChIP experiments were performed to study HIF‐1α's role in gene regulation, using IgG as an internal control for specificity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ChIP", "experiments", ...
PMC9688728	To evaluate possible changes in the physiological state of cultured cells during the experiment, some critical culture characteristics were tested at days 0 and 20.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10926885	NDE1 was knocked down, and the CCK‐8 experiment showed that this dramatically slowed cell growth (Figure 10I,J).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "NDE1", "was"...
PMC11765988	According to a study conducted by Cerri et al., patients with SLS exhibit even higher levels of ACE than patients with sarcoidosis or lymphoma alone .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11352877	This regression may be caused by different metabolic processes in a mixed mesodermal tumor, where cells express this transcription factor differently, i.e., carcinoma cells show higher expression of VEGF-A than sarcoma cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10870498	Interestingly, our results found that KIF23 was desuccinylated at K537 site, which has never been reported in previous studies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interestingly", ",", ...
PMC9910796	Vero cell monolayers, seeded in 24-well plates, were infected with 5 pfu/cell of recombinant vEP84Ri or parental BA71V.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Vero", "cell", "mon...
PMC10955424	Combination of modulators (Fig. 6A and B) with platinum compounds resulted in various responses.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Combination", "of", "modulators", "(", "Fig.", "6A", ...
PMC7823217	Adenocarcinoma is the most common type of colorectal cancer comprising around 95% of the cases .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Adenocarcinoma", "is", "the", "most", "common", "type"...
PMC11047729	It has four chemical analogs, but due to its pharmacological effects and the amount found in saffron, crocin 1 (alpha-crocin; crocetin digentiobiose ester) has been studied the most.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11218145	Next, cells were incubated for 30 min with the red fluorescent probe MitoSOX to detect the total ROS release from mitochondria.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Next", ",", ...
PMC10988808	Mouse tumor size was measured every 2 days using vernier calipers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mouse", "tumor", "size", "was", "measured", "every", "2", "days", "using", "vernier",...
PMC11592008	In summary, we elucidated the differences in NLPR1 inflammasome expression and function between different cell lines and PKs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "summary", ",", "we", ...
PMC11473843	Statistical analyses were done using one-way ANOVA; n, number of biologically independent samples.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "analyses", "were", "done", "using", "one-way", ...
PMC10969097	Also similar are the results of Gou et al. , where polysaccharides from Trametes robiniophila Murr were able to negatively regulate P-gp in human hepatocellular carcinoma cells and in nude mice in vivo .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9841531	The usefulness of pan-agents has been broadly discussed in the literature, and particularly intersuperfamily addressing molecules may be of great use to further explore target space and identify as well as validate potential pharmacological drug targets of the future.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11763764	Our results provide new mechanistic insights regarding the regulation of EGFR by SORL1 in ovarian cancer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Our", "results", "provide", "new", "mechanistic", "ins...
PMC9429973	Image: Summary/Conclusion: 18F-FDG PET/CT radiomic analysis with machine learning model provided a quantitative, objective and efficient mechanism for identifying BMI in the patients with suspected lymphoma.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11186948	RNA extraction from #249 and five HD LCLs pellets was obtained following TRIzol reagent protocol (#15596026 Invitrogen).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RNA", "extraction", ...
PMC7090062	d Western blotting was applied to assess the levels of autophagy-related proteins. **	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "d", "Western", "blotting", "was", "applied", "to", "assess", "th...
PMC8557138	3D bioprinting is proven beneficial in cases where exogenous administration of growth factors may lead to undesired effects.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "3D", "bioprinting", "is", "proven", "b...
PMC11534035	Expression of PAI1 in A431 (A, B) and CAL39 (C, D) cells treated with GPER1 agonist G1 (A, C) and GPER1 antagonist G36 (B, D) relative to ethanol treated control cells.	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC10667689	Therefore, one-way ANOVA, a parametric method, was used to compare the differences, and a p-value of < 0.05 was considered a statistically significant result.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11252553	Whole blood samples in three groups were irradiated at doses: 4, 8, and 12 Gy using a linear accelerator as an X-ray source.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10237474	These methods also require a few rounds of targeted cassette exchanges which leads to a lengthy stable cell line generation process .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "methods", ...
PMC9429973	Image: Summary/Conclusion: To our knowledge this is the most extensive descriptive report of mieloproliferative neoplasias in our country.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Image", ":", "Summary/Conclu...
PMC11782508	Notably, total apoptosis in azurin-treated cells increased approximately 12-fold compared to the control.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notably", ",", "total", "apoptosis", "in", "azurin-treated", "cells", ...
PMC11248911	Considering that g_mmpbsa only read the files of some specific GROMACS versions, the binary run input file (.tpr) required for MM-PBSA calculation through the g_mmpbsa was regenerated by GROMACS 5.1.4.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11656657	In this study, we provided evidence that the expression of B4GALNT1 (a GD2-synthase) is significantly associated with poor overall survival in pediatric sarcoma patients, as already reported in melanoma, where it is associated with tumorigenesis, angiogenesis, anchorage-independent growth, and motility , and in hepatoc...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8592717	Tables 2 and 3 provide details of the in vitro and in vivo antioxidant effects of PCA and PAL.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tables", "2", "and", "3", "...
PMC10723784	Carboplatin in combination with CBG exerted similar effects at 48 h (0.78), 72 h (0.71), and 96 h (0.65) contact times.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10529414	The potential associations with nearby genes related to RUNX2 binding were evaluated with the GREAT tool .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "potential", "associations", "with", "nearby", "...
PMC9429973	Results: A high correlation between dPCR and MFC was found (r = 0.90), demonstrating the usefulness of dPCR to quantify absolute number of CAR copies (Figure 1A and 1B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11361748

Pretreatment with Gö6976 prior to UVB Tx in TPA-primed skin resulted in a significant reduction of neutrophil dermal infiltration (S4D Fig).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Pretrea...

PMC4395774

Mouse primary NK cells were isolated from spleens of prf mice using CD49b (DX5) microbeads (Miltenyi Biotec, Woking, UK) following the manufacturer instructions.

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PMC7887261

II (# SL100489, SignaGen).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "II", "(", "#", "SL100489", ",", "SignaGen", ")", "." ] } ]

PMC11787355

In c, e–h, and j, N(biological)=4.

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PMC11621493

The base-exchange was verified by Sanger sequencing.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "base-exchange", "was", "verified", "by", "Sanger", "sequencing", "." ] } ]

PMC11790971

This qualitative inspection provided by these visualizations serves as an initial step in identifying cell line differences.

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PMC10882807

Cell proliferation ability was assessed by colony formation assays after HCCLM3 cells transfected with shNC + vector, shEIF4A3 + pcDNA or shEIF4A3 + pcDNA.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...

PMC11676169

For analyses comparing multiple experimental groups, the Kruskal–Wallis test (non-parametric test) was used.

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PMC11694066

Our work specifically underlines the translational potential of combining PARPi and ATRi in DSRCT, a combination that is currently being evaluated by multiple clinical trials, including in children (NCT02813135).

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PMC9429973

The cut-off point of ≥10 identifies probable cases of GAD that may require further psychiatric assessment.

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PMC10297204

At 0% ethanol concentration, the cells passed through the invasion chamber were stained with crystal violet.

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PMC11678368

The new complex, trans-[PtCl2(7AI3CA)2], exhibited cytotoxicity similar to that of cisplatin in LoVo (colon cancer) and MCF7 (breast cancer) cell lines, while its cytotoxicity was significantly lower in A549 (lung cancer) compared to cisplatin.

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PMC11502066

For covering all the subject, a systematic search for articles was performed by the words “flavonoid” and “cancer” and all individual members of GPCRs listed in the IUPHAR/BPS Guide to Pharmacology (excluding those belonging to the subclass of orphan and other 7TM receptors) .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11087766

The stalled intermediate colocalized with fluorescently tagged PicA foci on the nuclear periphery, suggesting a two-step import model in which proteins are first targeted to PicA and then licensed to be translocated across the nuclear shell by the import machinery (Fig. 5A).

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PMC11627398

Huo et al. found that advanced glycosylation end products could trigger cuproptosis in cardiomyocytes through upregulating SLC31A1 , suggesting that SLC31A1 may exert a pro-cuproptosis role.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC11544122

This is exemplified by SNX27, which has been shown to be required for the recycling of several GPCRs, including β2AR, parathyroid hormone receptor (PTHR), and 5-hydroxytryptamine 4A receptor (5-HT4AR).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11590005

The Modern Racism Scale (MRS) was developed to measure the cognitive component of subtle racial attitudes using a less reactive approach .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...

PMC11730305

The specific focus of this study is to investigate the anticancer potential of cobalt oxide nanoparticles (Co3O4) functionalized with glucose and conjugated with EA (Co3O4@Glu-Ellagic acid) in human liver cancer cell lines.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Results: After exclusion, 234 COVID-19 and 58 MERS-COV patients were included.

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PMC6160470

As a model for studying MDR related to overexpression of P-gp, we used ovarian carcinoma cell line A2780 and its adriamycin (doxorubicin) resistant counterpart A2780/Adr.

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PMC11761919

On day 5 dpi, sera were collected to detect inflammatory factors and enzymes, and liver tissues were sampled to quantify viral load.

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PMC11706776

In conclusion, our results have demonstrated the overexpression of KCNN1 in ES patients, identifying KCNN1 as a novel potential therapeutic target in this tumor.

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PMC10788478

Tumor cells with nuclear or cytoplasmic staining were defined as positive.

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PMC7823217

Various 3D bioprinting approaches have been used to develop biomimetic liver tissue constructs that can recapitulate native liver tissue microenvironment, vasculature and precise spatiotemporal signaling .

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PMC11371627

However, patients with pathogenic variants in exon 3 and in close proximity to the novel deletion of our patient (c.756del, p.Trp253Glyfs*15) did manifest with neuropathy and myopathy, frequently displaying areflexia, elevated CK and acanthocytosis without hepatopathy or cardiomyopathy.

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PMC11106977

Through this mechanism, OGT modulates almost every biological process that occurs within the cell.

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PMC6163708

NSCLC lung cancer cell lines A549, HT1299, A-427, Calu-1, H-460, H-520, H596, H-661, H-2170, and SK-MES-1, and SCLC cell lines H-446, H-69, H-209, H-82, H-345, H-146, H-378, H-196 were purchased from ATCC.

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PMC11545737

On the other hand, several pathogens have developed strategies to overcome or disrupt these barriers to gain access and invade host tissues.

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PMC9895440

Hs.eg.db_3.15.0, TxDb.

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PMC11707577

Data analysis was performed with CytExpert (Beckam Coulter) and FlowJo™.

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PMC6617630

Data represent mean ± SD from three independent experiments.

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PMC9429973

Thirty-one patients (84%) died during the induction cure with a median time between the start of the cure and death of 17 days [2-29].

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PMC11665555

Pathway enrichment analysis between untreated parental and 5637GR showed pyrimidine metabolism as among one of the significantly altered pathways in the development of gemcitabine resistance (Figure 4B and Supplemental Table 2).

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PMC10604092

We observed that SLC-transplanted rats exhibited severe anorexia, weight loss, muscle atrophy, and weakness.

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PMC11377827

Immunoblot of the soluble (S) and chromatin fractions (Ch) obtained using a formaldehyde crosslinking chromatin extraction protocol.

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PMC10178190

It is of interest to translate our in vitro results to validation in pre-clinical and clinical settings toward improving cancer therapy in ovarian cancer patients.

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PMC11155445

Similarly, the enhanced activity of benzene complexes of Ru as compared to p-cymene, was due to the presence of methyl and isopropyl groups on p-cymene which hindered the adduct formation (Fig. 17).

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PMC9516447

The quantitation of the relative KRAS protein level after normalization to GADPH levels is shown in the graphs below. (

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PMC10568263

The aqueous solutions of 30 μL MoO3 and 30 μL Au@MnO2 were dropped onto screen-printed electrodes (SPEs), respectively, and dried at 60 °C for 30 min.

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PMC8348645

1 × 10 cells) of treated and untreated cells were taken separately in a microcentrifuge tube and stained with 5 µL of AO-EtBr (acridine orange and ethidium bromide) for about 2 min followed by gentle mixing.

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PMC11467964

Kaplan–Meier survival curves demonstrated that the patients in the high‐risk group had a poor prognosis.

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PMC11394730

2-phenylchromenylium, also known as flavylium, is the basic structure of anthocyanin.

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PMC8996378

Studies have shown that the expression of ABCB1 is regulated by various signaling pathways, such as nuclear factor κB (NF-κB) (Sun et al., 2012), mitogen-activated protein kinases (MAPK) (Luo et al., 2016) and phosphoinositide-3-kinase–protein kinase B (PI3K-PKB) (Dong et al., 2017).

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PMC11590005

Different letters indicate statistically significant difference.

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PMC9424261

Interestingly, the same number of cell death or lipid ROS were produced in HERPUD1-sg1 cells when erastin or RSL3 were added after 1 h of CA pretreatment compared to wild-type liver cancer cells.

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PMC11055510

FISH assay detected the localization of circMAN1A2 in cells.

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PMC9429973

Participants’ ages ranged from 35 to 84 years (Median = 61).

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PMC9250505

Tissue was minced with scissors (except for AFC cells), and the tissue fragments or AFC cells were incubated in serum-free Advanced Dulbecco’s modified Eagle’s medium (DMEM)/F12 (Thermo Fisher Scientific, Inc., Waltham, MA, USA) containing 1.5 mg/ml collagenase IV (Gibco; Thermo Fisher Scientific, Inc.) and 1% penicill...

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PMC7823217

An interesting study indicated that tuning of rheological properties of sodium alginate-gelatin hydrogel improves the printability and viability of non-small cell lung cancer patient derived xenograft cells and cancer associated fibroblasts co-cultures, allowing for 3D spheroid development within the printed construct ...

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PMC9454852

For this reason, a confocal time-lapse analysis was performed to evaluate the [Ca]i variation induced by BOLD-100.

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PMC9429973

Expression of protein coding genes (PCGs), lncRNAs and circRNAs was bioinformatically processed.

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PMC11705484

Finally, we identified TRMT61A inhibitors using a virtual screening strategy and two compounds (abbreviated as CMP) were potentially effective in inhibiting TRMT61A (Figure 4A,B, Figures S6–S8 and Table S1).

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PMC11489351

However, despite being associated with these pH-dependent behaviors, Notch1 expression and activity have not been previously shown to be pH-sensitive.

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PMC11695623

GO functional annotation showed that the related genes were mainly enriched in chromosome segregation, chromosomal region and ATP-dependent activity, acting on DNA.

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PMC11155445

Huang et al. synthesized polyvinylidene fluoride (PVDF)/N-benzoyl-N′,N′-dibutyl thiourea (170) composite membrane for Ag adsorption by mixing PVDF and (170) in DMF.

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PMC11204465

AFB2a (75) was discovered while testing the ability of various microbes to detoxify AFB1 .

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PMC11746942

G Western blot analysis of P-STAT3 (Y705), STAT3, P-AKT (S473), P-AKT (T308), AKT, S1PR3, S1PR2, K16, Survivin, and GAPDH protein levels in HaCaT cells stimulated with IL-6 or IL-22 in the presence or absence of FTY720 pretreatment.

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PMC9429973

F. Peci, J. de Kanter, N. Groenen, A. Rosendahl-Huber, L. Derks, E. Bertrums, S. Middelkamp, M. J. van Roosmalen, R. van Boxtel Princess Máxima Center for Pediatric Oncology, Utrecht, Netherlands Background: Nucleoside analog (NAs) drugs are used for the treatment of a variety of diseases, such as cancers and viral inf...

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PMC11637276

NMuMG, PyMT#1, and YEJ P cells were a gift from Professor Jim Norman (CRUK Scotland Institute, Glasgow, United Kingdom).

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PMC11519583

To examine Wnt5a and Wnt5b function in MPs, we treated MPs with Wnt5a siRNAs or Wnt5b siRNAs.

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PMC11252033

Ovarian cancer is the deadliest gynaecologic malignancies worldwide.

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PMC11656657

No tumor bearing mice have been used as control group.

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PMC11463018

H NMR (500 MHz, DMSO-d6) δ: 11.16 (s, 1H), 8.97 (s, 1H), 8.03 − 7.98 (m, 2H), 7.72 − 7.68 (m, 2H), 7.54 − 7.49 (m, 1H), 7.44 − 7.31 (m, 6H), 7.08 − 7.04 (m, 1H), 4.46 (d, J = 6.3 Hz, 2H).

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PMC9096373

There were no significant differences in tumor volume between the APA + RT and DDPs + RT groups (only reduced by 5.3%; t=1.97, P>0.05).

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PMC9352806

300 μL of supernatant was transferred to a fresh tube and dried in a vacuum concentrator at 37 °C.

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PMC11011837

In order to obtain better results and minimize variations, cells from all four cell lines were seeded at the same concentration and, after 48 h, were harvested, counted, and collected into a pellet via centrifugation at 300× g, washed twice with phosphate-buffered saline (PBS), and stored at −80 °C until LC/MS analysis...

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PMC6487404

Monolayers displaying TEER values greater than 300 Ωcm were used for transport studies.

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PMC11745823

ChIP experiments were performed to study HIF‐1α's role in gene regulation, using IgG as an internal control for specificity.

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PMC9688728

To evaluate possible changes in the physiological state of cultured cells during the experiment, some critical culture characteristics were tested at days 0 and 20.

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PMC10926885

NDE1 was knocked down, and the CCK‐8 experiment showed that this dramatically slowed cell growth (Figure 10I,J).

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PMC11765988

According to a study conducted by Cerri et al., patients with SLS exhibit even higher levels of ACE than patients with sarcoidosis or lymphoma alone .

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PMC11352877

This regression may be caused by different metabolic processes in a mixed mesodermal tumor, where cells express this transcription factor differently, i.e., carcinoma cells show higher expression of VEGF-A than sarcoma cells .

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PMC10870498

Interestingly, our results found that KIF23 was desuccinylated at K537 site, which has never been reported in previous studies.

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PMC9910796

Vero cell monolayers, seeded in 24-well plates, were infected with 5 pfu/cell of recombinant vEP84Ri or parental BA71V.

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PMC10955424

Combination of modulators (Fig. 6A and B) with platinum compounds resulted in various responses.

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PMC7823217

Adenocarcinoma is the most common type of colorectal cancer comprising around 95% of the cases .

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PMC11047729

It has four chemical analogs, but due to its pharmacological effects and the amount found in saffron, crocin 1 (alpha-crocin; crocetin digentiobiose ester) has been studied the most.

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PMC11218145

Next, cells were incubated for 30 min with the red fluorescent probe MitoSOX to detect the total ROS release from mitochondria.

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PMC10988808

Mouse tumor size was measured every 2 days using vernier calipers.

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PMC11592008

In summary, we elucidated the differences in NLPR1 inflammasome expression and function between different cell lines and PKs.

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PMC11473843

Statistical analyses were done using one-way ANOVA; n, number of biologically independent samples.

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PMC10969097

Also similar are the results of Gou et al. , where polysaccharides from Trametes robiniophila Murr were able to negatively regulate P-gp in human hepatocellular carcinoma cells and in nude mice in vivo .

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PMC9841531

The usefulness of pan-agents has been broadly discussed in the literature, and particularly intersuperfamily addressing molecules may be of great use to further explore target space and identify as well as validate potential pharmacological drug targets of the future.

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PMC11763764

Our results provide new mechanistic insights regarding the regulation of EGFR by SORL1 in ovarian cancer.

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PMC9429973

Image: Summary/Conclusion: 18F-FDG PET/CT radiomic analysis with machine learning model provided a quantitative, objective and efficient mechanism for identifying BMI in the patients with suspected lymphoma.

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PMC11186948

RNA extraction from #249 and five HD LCLs pellets was obtained following TRIzol reagent protocol (#15596026 Invitrogen).

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PMC7090062

d Western blotting was applied to assess the levels of autophagy-related proteins. **

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PMC8557138

3D bioprinting is proven beneficial in cases where exogenous administration of growth factors may lead to undesired effects.

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PMC11534035

Expression of PAI1 in A431 (A, B) and CAL39 (C, D) cells treated with GPER1 agonist G1 (A, C) and GPER1 antagonist G36 (B, D) relative to ethanol treated control cells.

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PMC10667689

Therefore, one-way ANOVA, a parametric method, was used to compare the differences, and a p-value of < 0.05 was considered a statistically significant result.

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PMC11252553

Whole blood samples in three groups were irradiated at doses: 4, 8, and 12 Gy using a linear accelerator as an X-ray source.

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PMC10237474

These methods also require a few rounds of targeted cassette exchanges which leads to a lengthy stable cell line generation process .

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PMC9429973

Image: Summary/Conclusion: To our knowledge this is the most extensive descriptive report of mieloproliferative neoplasias in our country.

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PMC11782508

Notably, total apoptosis in azurin-treated cells increased approximately 12-fold compared to the control.

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PMC11248911

Considering that g_mmpbsa only read the files of some specific GROMACS versions, the binary run input file (.tpr) required for MM-PBSA calculation through the g_mmpbsa was regenerated by GROMACS 5.1.4.

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PMC11656657

In this study, we provided evidence that the expression of B4GALNT1 (a GD2-synthase) is significantly associated with poor overall survival in pediatric sarcoma patients, as already reported in melanoma, where it is associated with tumorigenesis, angiogenesis, anchorage-independent growth, and motility , and in hepatoc...

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PMC8592717

Tables 2 and 3 provide details of the in vitro and in vivo antioxidant effects of PCA and PAL.

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PMC10723784

Carboplatin in combination with CBG exerted similar effects at 48 h (0.78), 72 h (0.71), and 96 h (0.65) contact times.

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PMC10529414

The potential associations with nearby genes related to RUNX2 binding were evaluated with the GREAT tool .

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PMC9429973

Results: A high correlation between dPCR and MFC was found (r = 0.90), demonstrating the usefulness of dPCR to quantify absolute number of CAR copies (Figure 1A and 1B).

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