OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11700247	This experiment demonstrated that the transfer of T cells from the A20 model treated with RT plus CART-19 provided significant protection against CT26 tumors, compared with the T cells from the CART-19 alone treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "...
PMC11718109	Interestingly, knockdown of AP2, an adaptor protein essential for clathrin-mediated endocytosis, did not impede formation of both VMAT2 and synaptophysin vesicle clusters (Supplementary Fig. 7), suggesting Golgi-dependent mechanisms for these vesicles, in addition to endocytic origins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11785489	Input gene expression was log10CPK-normalized and scaled to mean 0 variance 1; input protein expression was CLR-normalized and scaled to mean 0 variance 1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11454387	Then, we validated the method to confirm the known interaction between H6PD and 11β-HSD1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", "we", "validated", "the", "method", "to", ...
PMC9429973	Estimated PFS-rates after 1 year were 88% in the total population and 86% and 90% in the TP53 aberrant and TP53 wt population, respectively (figure).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11787651	The mass spectrometer was operated in DIA mode with an MS1 scan range of m/z 290 to 1115 at 60,000 resolution and an MS2 resolution of 15,000.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11310713	To assess the viability and hormone synthesis function of ovarian endocrine cells within GTBs, the GTBs were plated on semipermeable transwell inserts (Corning, NY, USA) and cultured for 90 days in the transwell system.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11499381	These mean intensity values from biological replicates were then combined for analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "mean", "intensity", "values", "from", "biological", "replicates", "were", ...
PMC9429973	Therefore, OS data for BTKi-naive C+O patients were digitized and compared with A±O from ELEVATE-TN.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "OS", "data", "for", "BTKi-naive", ...
PMC11496728	Cells were obtained after 14 days of screening pools.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "obtained", "after", "14", "days", "of", "screening", "pools", "." ] } ]
PMC9503685	Samples were vortexed for 3 min, and the suspension was collected and serial dilutions were prepared.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Samples", "were", "vortexed", "for", "3", "...
PMC11607321	c Dimensionality reduction visualized using Uniform Manifold Approximation and Projection (UMAP) representation of the trained MOSA joint latent space, where each dot represents a cancer cell line colored according to its tissue of origin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10547921	Julia Gavrilyuk et al. selected the methylamine analog 50 as the uncialamycin ADC payload, and ADCs targeting TL and CD46 exhibited low picomole potency in HEK293T cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellL...
PMC11257988	ReferencePatients tested for KRASPatients by KRAS statusTreatment armEndpointKRAS-mutKRAS-wtConclusionKRAS-mutKRAS-wtShepherd et al. 1543 (not specified)3001243Cisplatin-based ACTOSNANANo difference.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ReferencePatients", "tested", "for", "KRASPatients", "by", ...
PMC10170482	Created with BioRender.com.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "Created", "with", "BioRender.com", "." ] } ]
PMC11754436	Total RNA was isolated from tissues and cells using TRIzol reagent (10296-028; Invitrogen; Thermo Fisher Scientific, Inc.) according to the manufacturer’s instructions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	46% were females.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "46", "%", "were", "females", "." ] } ]
PMC11413393	Dried peptides were reconstituted in 0.1% HCOOH and injected on a loading column (C18 Acclaim PepMapTM 468 100, 75 μM × 2 cm, 3μm, 100Å) prior to separation on an analytical column (C18 Acclaim PepMapTM 469 RSLC, 75 μm × 50 cm, 2μm, 100Å) by HPLC over a reversed-phase gradient (120-min gradient, 5–30% CH3CN in 0.1% HCO...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11705547	Therefore, various combination treatment strategies have been devised to enhance patient responsiveness to cisplatin therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "various", "combination", "treatment", ...
PMC11767582	The search for new anti-cancer drugs and the development of more effective treatment strategies is a field of utmost importance in the current drug discovery and clinical research.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11786704	Due to insufficient antioxidant capacity, diabetic patients are unable to effectively eliminate excess ROS, leading to persistent oxidative stress , which aggravates inflammation through the MAPK signaling pathway and further complicates wound healing .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11574029	Previous studies have shown that the PI3K/AKT signaling pathway is a key pathway controlling cell functions in mammalian cells, and its abnormal activation can promote tumor development and progression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11782780	Our findings generated new insights into the role of miR-301b-3p/EBF3 in BC stem-like phenotype, providing a novel therapeutic avenue for BC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Our", "findi...
PMC8759873	Compared with untreated and 786-0 cells that are transfected with empty vector, the expression level of VHL gene mRNA in 786-0 cells that are transfected with pcDNA3.1-VHL was significantly increased, and the cell growth inhibition rate was significantly higher.	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", ...
PMC9412887	Thereby, there is an urgent need to design an effective strategy for surmounting drug-resistant brain metastases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thereby", ",", "there", "is", "an", "urgent...
PMC10203589	According to their molecular structure, 22 FGFs species could be divided into 7 subgroups, among which, FGF8, FGF17 and FGF18 belonged to the FGF8 family subfamily (11, 14, 17).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11098378	However, a wide array of human cancer cell lines and tumor types have been shown to be refractory to VSVΔM51/M51R replication, presumably due restriction pathways that are still active in transformed cells [68–72].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Secondary end points were non-relapse mortality (NRM) and acute (a) and chronic (c) Graft Versus Host Disease (GVHD) in allogeneic transplanted patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11594806	ATIC is transported into cells via adenosine (ADO) transporters and converted by adenosine kinase into the monophosphorylated derivative AICAR, which, as noted earlier, mimics AMP in activating AMPK .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11748618	Genomic data was obtained from ten independent GWAS and permission for use was obtained from the ICGH cohort.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Genomic", "data", "was", "obtained", "...
PMC11612626	.	[ { "tags": [ "O" ], "tokens": [ "." ] } ]
PMC8978939	On the other hand, when cell lines were treated with the proteasome inhibitor MG132, we observed accumulation of WT pVHL, P138R, and L163R.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11488203	Two fractions containing the maximal number of EVs/exosomes as analysed by NTA (see below) were pooled and ultracentrifuged (100,000 g/70 min).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC7802142	a Western blotting and b quantitative analyses of β-catenin in nucleus were performed 48 h after treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "a", "Western", "blotting", "and", "b", "qua...
PMC9429973	The proliferation of JAK2wt UT-7 cells was significantly reduced in the presence of TGFβ 10ng/mL while JAK2V617F UT-7 cells were not affected.	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O" ], "tokens": [ "...
PMC9429973	In the low probability group,166(90.7%) of patients had negative HIT Eliza (Table 1 & 2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "low", "probability",...
PMC10604092	As a result, increases in lipid mobilization and resting energy expenditure are observed .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "a", "result", ",", "increases", "in", "lipid", "mobilizati...
PMC7823217	However, a modified hanging drop method following addition of methylcellulose polymer was capable of growing uniform and reproducible spheroids for all five of the tested human pancreatic cancer cell lines; Panc-1, BxPC-3, Capan-1, MiaPaCa-2, and AsPC-1 .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11705862	By performing immunostaining of postmortem human hippocampal tissue, we can for the first time, report expression of IRIS-1 and 2 in neurons.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10530622	Two distinct clinical expressions are defined for hyperoxaluria, namely primary hyperoxaluria (PH) and secondary hyperoxaluria.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Two", "distinct", "clinical", "expressions",...
PMC11585587	The targets of MM were obtained from Gene Cards (https://www.genecards.org/) and OMIM (https://www.omim.org/).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "targets", "of", "MM", "were", "obtai...
PMC10135767	The ratio of the highest fluorescence intensity to the average fluorescence intensity during the delay period was used to define the peak calcium intensity (IP), which represents the complete release of cytosolic calcium ions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10538569	CNE11 is derived from an R5-tropic subtype B’ virus.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CNE11", "is", "derived", "from", "an", "R5-tropic", "subtype", "B", "’", "virus", "." ...
PMC7351993	Specifically, different from traditional high-content screening, their ability to physically isolate target cells from large heterogeneous populations serves as a tool to identify the links between the spatial architecture of molecules within the cell (e.g., protein localization, receptor clustering, nuclear shape, cyt...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11680049	The increased volume of transfusion tissue in Sequoia contributes to enhanced hydraulic conductivity at the leaf level, thereby reducing radial resistance and increasing the maximum rate of photosynthesis .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10213179	All cell incubations were carried out at 37°C with 5% CO2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "cell", "incubations", "were", "carried", "out", "at", "37...
PMC11705630	These findings reveal that GLDC regulates RCC progression via ISFG3-mediated pathway and offers a promising strategy for RCC treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "findings", "reveal", "th...
PMC11381192	p < 0.05, p < 0.01, *p < 0.001.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "p", "<", "0.05", ",", "", "", "p", "<", ...
PMC11269792	Finally, RNA expression levels were quantitatively analyzed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Finally", ",", "RNA", "expression", "levels", "were", "quantitatively", "analyzed", "." ] } ]
PMC11060216	Researchers detected S100A6 expression in archival tumor cell lysates from 39 patients with resected NSCLC, their study validated that S100A6 expression has a direct correlation with nonsquamous histology, and an inverse relationship with P53 expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9812014	Alkaloids tested in this experiment showed significant inhibition and reduction of the cytopathogenic effect (CPE) caused by this virus in MDBK cell culture with an inhibitory concentration of 0.8 µg/mL for Yohimbine, 0.8 µg/mL for vincamine, 0.8 µg/mL for atropine, 0.4 µg/mL for trigonelline and 0.4 µg/mL for capsaici...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", ...
PMC10329074	Kaplan–Meier curves for overall survival of T1 subgroups for TCGA-KIRC samples. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Kaplan", "–", "Meier", "curves", "for", "overall", "survival", "...
PMC9429973	One of the ways of study the BM stroma is the analysis of colony-forming units of fibroblasts (CFU-F).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "of", "the", "wa...
PMC11224020	On day 4, 40 ml of fresh pTRIP-SFFV-GFP-NLS lentivector supernatant was loaded in Ultra-Clear Centrifuge tubes (Beckman Coulter) and ultracentrifuged at 100,000g in a SW32 rotor (Beckman Coulter) for 90 min at 4 °C and resuspended in 400 µl of DC medium.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9596868	After blocking with 5% normal goat serum (Santa Cruz Biotechnology, USA, Cat no. sc-2043) for 1 h at room temperature, the cells were incubated with primary antibody, mouse monoclonal anti-phospho-Histone H2A.X (Ser139) clone JBW301 from Sigma-Aldrich (Cat.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	MTD has not yet been reached.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MTD", "has", "not", "yet", "been", "reached", "." ] } ]
PMC9429973	In VIALE-C, MRD<10 was achieved by 9 of 64 evaluable pts, of whom 6 (67%) had post-remission G-CSF.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC11012313	EBV increases ATP generation through multiple pathways, indicating that it is in the virus’s best interest to enhance the availability of ATP for survival and/or re-entry into the lytic pathway .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11803210	Labels represent upregulated genes involved in estrogen signaling.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Labels", "represent", "upregulated", "genes", "involved", "in", "estrogen", "signaling", "." ] } ]
PMC11266100	As in the case of our study, the transfected 4T1 cell line allowed for the assessment of tumor growth and metastasis progression (Tao et al., 2008).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Results: A total of 175 patients were included.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "A", "total", "of", "175", "patients", "were", "included", "." ] } ]
PMC9429973	There were 1.049 in the rituximab group with a median age of 69 years and 1.343 in the biosimilar rituximab group, median age 71 years.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973	209 patients received HMA (21.4%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "209", "patients", "received", "HMA", "(", "21.4", "%", ")", "." ] } ]
PMC11721277	The resulting solution was stirred for 40 min at 25 °C, then was extracted with CH2Cl2 (20 mL) and washed with citrate buffer solution (pH = 4.00, 2 × 10 mL).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10142392	It has also been established in this paper that a well-controlled polymerization processes is a key goal to prepare different forms of multiarms according to their intended applications, which enable better control of the biocompatibility, biostability, and biodegradability of the desired architecture.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8540611	The fraction of necrotic cells both in the general population and the population of FAM-positive cells is approximately equal.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "fraction", "of", "necrotic...
PMC11772585	G The mRNA level of Pcna was evaluated by qRT-PCR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "G", "The", "mRNA", "level", "of", "Pcna", "was", "evaluated", "by", "qRT-PCR", "." ] ...
PMC10674574	Due to the significant increase in permeability studies using the Caco-2 cell line in recent years, the need to standardize this biological model seems necessary.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11655536	E Apoptosis assay of RPMI-8226/TFE3 KD (upper) and U266/TFE3 KD (lower) treated with HA at 10 μM. F Statistical analysis of apoptotic cells for RPMI-8226/TFE3 KD cells (upper) and U266/TFE3 KD cells (lower) in (E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6133382	Cell counts were performed using a TC20 automated cell counter (BioRad, Hercules, CA, US) with viability determined by trypan blue (Thermo Fisher, Life Technologies, Carlsbad, CA, US) exclusion.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6642070	Dose-response of fluvastatin treatment for 48 h on lactate production in A-204 cells and C2C12 myotubes (n = 3). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "...
PMC9429973	In the anti-CD20 MoAb treated cohort, of which 27 patients were still on active treatment at the time of vaccination, only 2 patients (7%) developed a humoral immune response, while cellular immunity was elicited in 52% (N = 15) patients (ELISA assay).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10809689	Based on diagrams (a., c.) and protein bands (b., d.), the expression of these proteins in the Gal-9 treated group compared to the control and PMA group had a significant increase at 24 h after Gal-9 treatment (PG24) (p = 0.0001) followed by a decrease at 48th hour.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11767725	Furthermore, emerging research suggests that probiotics and postbiotics can alter the skin’s pH and lipid composition, creating an environment less conducive to pathogenic bacterial colonization.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11674441	After three washes with RPMI-1640 medium, 2 × 10⁵ autologous peripheral lymphocytes, isolated from cryopreserved PBMCs obtained pre- and post-vaccine therapy, were added to each well.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10125312	Laser settings (power density, beam diameter, time of irradiation) must be planned to increase local temperature, avoiding damage to cells without nanoparticles.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10366908	All animal experiments were approved by the Animal Care and Use Committee of Tohoku University (Permit number: 2022MdA-001).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "animal", "...
PMC11705484	NF‐κB activation facilitated the nuclear translocation of TRMT61A (Figure 3H–L).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "NF‐κB", "activation", "facilitated", "the", "nuclear", "translocation", ...
PMC11731614	Samples underwent small RNA sequencing through Northwestern’s core facilities.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Samples", "underwent", "small", "RNA", "sequencing", "through", "Northwestern", "’s", "core", "f...
PMC11672142	Cw-EPR spectra were collected at the University of Arizona, EPR Facility on an X-band EPR Elexsys E500 spectrometer (Bruker) equipped with an ESR900 flow cryostat (Oxford instruments).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11657695	The expression of the multiple KCNA2 transcripts was then studied in various cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "expression", "of", "the", "multiple", "KCNA2", "transcripts", ...
PMC11200978	Additionally, A549 regrowth was reduced in comparison to either −15 °C or gemcitabine alone samples (12.0% (±0.6) vs. 132.9% (±3.4) or 56.7% (±1.7) on day 7, respectively, p < 0.01).	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9812014	Lamivudine (3TC) was able to inhibit the HBV virus to 31.5 percent when its concentration was 1.0 mM while the isolated alkaloids sophaline B and sophaline D significantly repressed the secretion of the HBsAg more than 50 percent.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11609529	These findings and those of others demonstrate that the YM fusion event represents a distinct mechanism for aberrant YAP1 signaling activation that drives tumor development and maintenance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7192625	Results show combinations of 1 active and 1 repressive mark to be assortative in AND-ChAs but to have negative cross-ChAs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", "show", "combinati...
PMC8662250	We can hypothesize that the in vitro inhibitory propriety of CBD on CYP450 (Millar et al., 2019) may increase plasma concentrations of other medications.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11696659	Telomere analysis showed that patients in the cancer cohort had a higher proportion of short telomeres compared to the control cohort.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Telomere", "analysis", ...
PMC11754432	ALOX5 is known to be expressed in macrophages and neutrophils, and a faint band was present for ALOX5 for both keratinocytes and fibroblasts.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11806106	3Characterization of MOR BRET-based receptor conformation sensor.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "3Characterization", "of", "MOR", "BRET-based", "receptor", "conformation", "sensor", "." ] } ]
PMC8193813	The CO2-K30 sensor was measured to have a t95 response time at 6000 ppm CO2 of 9.0 ± 0.0s and a noise level of 1.6 ppm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11794568	Existing melanoma treatments, such as immune checkpoint inhibitors and BRAF-targeted regimens, still suffer from problems such as drug resistance and side effects, although they have improved patient survival to some extent.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	This year he presented with important lower and upper extremities edema, oliguria (1100ml / 24h), minor increase of lymph nodes and spleen; laboratory test showed: haemoglobin: 11.4 g / dl, white blood cells: 186.020 / mm3, platelet count 207.000 / mm3, urea: 126 mg / dl, creatinine: 1.94 mg / dl; urinary protein excre...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3203927	A ratio of 1.8–2.1 was considered a “clean” sample and could be used in microarray experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "ratio", "of", "1.8–2.1", "was", ...
PMC2118063	The cells were infected with a retrovirus that expressed puromycin and either of two siRNA for IRF8 or a nonreactive siRNA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cells", "w...
PMC9429973	Individual patient datasets were used to plot Kaplan-Meier (KM) curves and calculate hazard ratios (HR) using Cox regression in R software.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10170482	Control cells were untreated.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Control", "cells", "were", "untreated", "." ] } ]
PMC11740207	For the negative marker for VSELSCs, we selected receptor-type tyrosine-protein phosphatase C (CD45 antigen) since it is commonly used by researchers (Lacombe et al., 1997; Kuruca et al., 2019; Filidou et al., 2023) and is part of the EuroFlow standardization for hematological probes (Van Dongen et al., 2012; Glier et ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	All responding pts except 1 remain on therapy (PVR responder discontinued due to death unrelated to study treatment).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "responding", "pts", ...
PMC9429973	Methods: We analyzed updated follow-up data on all patients (pts) treated within the LH-05 GATLA trial.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Methods", ":", "We", "analyzed", ...
PMC11055510	CCK8 analyzed the effect of miR-135a-3p interaction with IL1RAP on the proliferation of SKOV3 cells. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "CCK8", "analyzed", "the", "effect", "of", "mi...

PMC11700247

This experiment demonstrated that the transfer of T cells from the A20 model treated with RT plus CART-19 provided significant protection against CT26 tumors, compared with the T cells from the CART-19 alone treatment.

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PMC11718109

Interestingly, knockdown of AP2, an adaptor protein essential for clathrin-mediated endocytosis, did not impede formation of both VMAT2 and synaptophysin vesicle clusters (Supplementary Fig. 7), suggesting Golgi-dependent mechanisms for these vesicles, in addition to endocytic origins.

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PMC11785489

Input gene expression was log10CPK-normalized and scaled to mean 0 variance 1; input protein expression was CLR-normalized and scaled to mean 0 variance 1.

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PMC11454387

Then, we validated the method to confirm the known interaction between H6PD and 11β-HSD1.

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PMC9429973

Estimated PFS-rates after 1 year were 88% in the total population and 86% and 90% in the TP53 aberrant and TP53 wt population, respectively (figure).

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PMC11787651

The mass spectrometer was operated in DIA mode with an MS1 scan range of m/z 290 to 1115 at 60,000 resolution and an MS2 resolution of 15,000.

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PMC11310713

To assess the viability and hormone synthesis function of ovarian endocrine cells within GTBs, the GTBs were plated on semipermeable transwell inserts (Corning, NY, USA) and cultured for 90 days in the transwell system.

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PMC11499381

These mean intensity values from biological replicates were then combined for analysis.

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PMC9429973

Therefore, OS data for BTKi-naive C+O patients were digitized and compared with A±O from ELEVATE-TN.

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PMC11496728

Cells were obtained after 14 days of screening pools.

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PMC9503685

Samples were vortexed for 3 min, and the suspension was collected and serial dilutions were prepared.

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PMC11607321

c Dimensionality reduction visualized using Uniform Manifold Approximation and Projection (UMAP) representation of the trained MOSA joint latent space, where each dot represents a cancer cell line colored according to its tissue of origin.

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PMC10547921

Julia Gavrilyuk et al. selected the methylamine analog 50 as the uncialamycin ADC payload, and ADCs targeting TL and CD46 exhibited low picomole potency in HEK293T cells.

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PMC11257988

ReferencePatients tested for KRASPatients by KRAS statusTreatment armEndpointKRAS-mutKRAS-wtConclusionKRAS-mutKRAS-wtShepherd et al. 1543 (not specified)3001243Cisplatin-based ACTOSNANANo difference.

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PMC10170482

Created with BioRender.com.

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PMC11754436

Total RNA was isolated from tissues and cells using TRIzol reagent (10296-028; Invitrogen; Thermo Fisher Scientific, Inc.) according to the manufacturer’s instructions.

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PMC9429973

46% were females.

[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "46", "%", "were", "females", "." ] } ]

PMC11413393

Dried peptides were reconstituted in 0.1% HCOOH and injected on a loading column (C18 Acclaim PepMapTM 468 100, 75 μM × 2 cm, 3μm, 100Å) prior to separation on an analytical column (C18 Acclaim PepMapTM 469 RSLC, 75 μm × 50 cm, 2μm, 100Å) by HPLC over a reversed-phase gradient (120-min gradient, 5–30% CH3CN in 0.1% HCO...

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PMC11705547

Therefore, various combination treatment strategies have been devised to enhance patient responsiveness to cisplatin therapy.

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PMC11767582

The search for new anti-cancer drugs and the development of more effective treatment strategies is a field of utmost importance in the current drug discovery and clinical research.

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PMC11786704

Due to insufficient antioxidant capacity, diabetic patients are unable to effectively eliminate excess ROS, leading to persistent oxidative stress , which aggravates inflammation through the MAPK signaling pathway and further complicates wound healing .

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PMC11574029

Previous studies have shown that the PI3K/AKT signaling pathway is a key pathway controlling cell functions in mammalian cells, and its abnormal activation can promote tumor development and progression.

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PMC11782780

Our findings generated new insights into the role of miR-301b-3p/EBF3 in BC stem-like phenotype, providing a novel therapeutic avenue for BC.

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PMC8759873

Compared with untreated and 786-0 cells that are transfected with empty vector, the expression level of VHL gene mRNA in 786-0 cells that are transfected with pcDNA3.1-VHL was significantly increased, and the cell growth inhibition rate was significantly higher.

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PMC9412887

Thereby, there is an urgent need to design an effective strategy for surmounting drug-resistant brain metastases.

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PMC10203589

According to their molecular structure, 22 FGFs species could be divided into 7 subgroups, among which, FGF8, FGF17 and FGF18 belonged to the FGF8 family subfamily (11, 14, 17).

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PMC11098378

However, a wide array of human cancer cell lines and tumor types have been shown to be refractory to VSVΔM51/M51R replication, presumably due restriction pathways that are still active in transformed cells [68–72].

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PMC9429973

Secondary end points were non-relapse mortality (NRM) and acute (a) and chronic (c) Graft Versus Host Disease (GVHD) in allogeneic transplanted patients.

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PMC11594806

ATIC is transported into cells via adenosine (ADO) transporters and converted by adenosine kinase into the monophosphorylated derivative AICAR, which, as noted earlier, mimics AMP in activating AMPK .

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PMC11748618

Genomic data was obtained from ten independent GWAS and permission for use was obtained from the ICGH cohort.

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PMC11612626

.

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PMC8978939

On the other hand, when cell lines were treated with the proteasome inhibitor MG132, we observed accumulation of WT pVHL, P138R, and L163R.

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PMC11488203

Two fractions containing the maximal number of EVs/exosomes as analysed by NTA (see below) were pooled and ultracentrifuged (100,000 g/70 min).

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PMC7802142

a Western blotting and b quantitative analyses of β-catenin in nucleus were performed 48 h after treatment.

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PMC9429973

The proliferation of JAK2wt UT-7 cells was significantly reduced in the presence of TGFβ 10ng/mL while JAK2V617F UT-7 cells were not affected.

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PMC9429973

In the low probability group,166(90.7%) of patients had negative HIT Eliza (Table 1 & 2).

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PMC10604092

As a result, increases in lipid mobilization and resting energy expenditure are observed .

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PMC7823217

However, a modified hanging drop method following addition of methylcellulose polymer was capable of growing uniform and reproducible spheroids for all five of the tested human pancreatic cancer cell lines; Panc-1, BxPC-3, Capan-1, MiaPaCa-2, and AsPC-1 .

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PMC11705862

By performing immunostaining of postmortem human hippocampal tissue, we can for the first time, report expression of IRIS-1 and 2 in neurons.

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PMC10530622

Two distinct clinical expressions are defined for hyperoxaluria, namely primary hyperoxaluria (PH) and secondary hyperoxaluria.

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PMC11585587

The targets of MM were obtained from Gene Cards (https://www.genecards.org/) and OMIM (https://www.omim.org/).

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PMC10135767

The ratio of the highest fluorescence intensity to the average fluorescence intensity during the delay period was used to define the peak calcium intensity (IP), which represents the complete release of cytosolic calcium ions.

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PMC10538569

CNE11 is derived from an R5-tropic subtype B’ virus.

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PMC7351993

Specifically, different from traditional high-content screening, their ability to physically isolate target cells from large heterogeneous populations serves as a tool to identify the links between the spatial architecture of molecules within the cell (e.g., protein localization, receptor clustering, nuclear shape, cyt...

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PMC11680049

The increased volume of transfusion tissue in Sequoia contributes to enhanced hydraulic conductivity at the leaf level, thereby reducing radial resistance and increasing the maximum rate of photosynthesis .

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PMC10213179

All cell incubations were carried out at 37°C with 5% CO2.

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PMC11705630

These findings reveal that GLDC regulates RCC progression via ISFG3-mediated pathway and offers a promising strategy for RCC treatment.

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PMC11381192

p < 0.05, **p < 0.01, ***p < 0.001.

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PMC11269792

Finally, RNA expression levels were quantitatively analyzed.

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PMC11060216

Researchers detected S100A6 expression in archival tumor cell lysates from 39 patients with resected NSCLC, their study validated that S100A6 expression has a direct correlation with nonsquamous histology, and an inverse relationship with P53 expression.

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PMC9812014

Alkaloids tested in this experiment showed significant inhibition and reduction of the cytopathogenic effect (CPE) caused by this virus in MDBK cell culture with an inhibitory concentration of 0.8 µg/mL for Yohimbine, 0.8 µg/mL for vincamine, 0.8 µg/mL for atropine, 0.4 µg/mL for trigonelline and 0.4 µg/mL for capsaici...

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PMC10329074

Kaplan–Meier curves for overall survival of T1 subgroups for TCGA-KIRC samples. (

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PMC9429973

One of the ways of study the BM stroma is the analysis of colony-forming units of fibroblasts (CFU-F).

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PMC11224020

On day 4, 40 ml of fresh pTRIP-SFFV-GFP-NLS lentivector supernatant was loaded in Ultra-Clear Centrifuge tubes (Beckman Coulter) and ultracentrifuged at 100,000g in a SW32 rotor (Beckman Coulter) for 90 min at 4 °C and resuspended in 400 µl of DC medium.

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PMC9596868

After blocking with 5% normal goat serum (Santa Cruz Biotechnology, USA, Cat no. sc-2043) for 1 h at room temperature, the cells were incubated with primary antibody, mouse monoclonal anti-phospho-Histone H2A.X (Ser139) clone JBW301 from Sigma-Aldrich (Cat.

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PMC9429973

MTD has not yet been reached.

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PMC9429973

In VIALE-C, MRD<10 was achieved by 9 of 64 evaluable pts, of whom 6 (67%) had post-remission G-CSF.

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PMC11012313

EBV increases ATP generation through multiple pathways, indicating that it is in the virus’s best interest to enhance the availability of ATP for survival and/or re-entry into the lytic pathway .

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PMC11803210

Labels represent upregulated genes involved in estrogen signaling.

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PMC11266100

As in the case of our study, the transfected 4T1 cell line allowed for the assessment of tumor growth and metastasis progression (Tao et al., 2008).

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PMC9429973

Results: A total of 175 patients were included.

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PMC9429973

There were 1.049 in the rituximab group with a median age of 69 years and 1.343 in the biosimilar rituximab group, median age 71 years.

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PMC9429973

209 patients received HMA (21.4%).

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PMC11721277

The resulting solution was stirred for 40 min at 25 °C, then was extracted with CH2Cl2 (20 mL) and washed with citrate buffer solution (pH = 4.00, 2 × 10 mL).

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PMC10142392

It has also been established in this paper that a well-controlled polymerization processes is a key goal to prepare different forms of multiarms according to their intended applications, which enable better control of the biocompatibility, biostability, and biodegradability of the desired architecture.

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PMC8540611

The fraction of necrotic cells both in the general population and the population of FAM-positive cells is approximately equal.

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PMC11772585

G The mRNA level of Pcna was evaluated by qRT-PCR.

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PMC10674574

Due to the significant increase in permeability studies using the Caco-2 cell line in recent years, the need to standardize this biological model seems necessary.

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PMC11655536

E Apoptosis assay of RPMI-8226/TFE3 KD (upper) and U266/TFE3 KD (lower) treated with HA at 10 μM. F Statistical analysis of apoptotic cells for RPMI-8226/TFE3 KD cells (upper) and U266/TFE3 KD cells (lower) in (E).

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PMC6133382

Cell counts were performed using a TC20 automated cell counter (BioRad, Hercules, CA, US) with viability determined by trypan blue (Thermo Fisher, Life Technologies, Carlsbad, CA, US) exclusion.

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PMC6642070

Dose-response of fluvastatin treatment for 48 h on lactate production in A-204 cells and C2C12 myotubes (n = 3). (

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PMC9429973

In the anti-CD20 MoAb treated cohort, of which 27 patients were still on active treatment at the time of vaccination, only 2 patients (7%) developed a humoral immune response, while cellular immunity was elicited in 52% (N = 15) patients (ELISA assay).

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PMC10809689

Based on diagrams (a., c.) and protein bands (b., d.), the expression of these proteins in the Gal-9 treated group compared to the control and PMA group had a significant increase at 24 h after Gal-9 treatment (PG24) (p = 0.0001) followed by a decrease at 48th hour.

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PMC11767725

Furthermore, emerging research suggests that probiotics and postbiotics can alter the skin’s pH and lipid composition, creating an environment less conducive to pathogenic bacterial colonization.

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PMC11674441

After three washes with RPMI-1640 medium, 2 × 10⁵ autologous peripheral lymphocytes, isolated from cryopreserved PBMCs obtained pre- and post-vaccine therapy, were added to each well.

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PMC10125312

Laser settings (power density, beam diameter, time of irradiation) must be planned to increase local temperature, avoiding damage to cells without nanoparticles.

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PMC10366908

All animal experiments were approved by the Animal Care and Use Committee of Tohoku University (Permit number: 2022MdA-001).

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PMC11705484

NF‐κB activation facilitated the nuclear translocation of TRMT61A (Figure 3H–L).

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PMC11731614

Samples underwent small RNA sequencing through Northwestern’s core facilities.

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PMC11672142

Cw-EPR spectra were collected at the University of Arizona, EPR Facility on an X-band EPR Elexsys E500 spectrometer (Bruker) equipped with an ESR900 flow cryostat (Oxford instruments).

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PMC11657695

The expression of the multiple KCNA2 transcripts was then studied in various cell lines.

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PMC11200978

Additionally, A549 regrowth was reduced in comparison to either −15 °C or gemcitabine alone samples (12.0% (±0.6) vs. 132.9% (±3.4) or 56.7% (±1.7) on day 7, respectively, p < 0.01).

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PMC9812014

Lamivudine (3TC) was able to inhibit the HBV virus to 31.5 percent when its concentration was 1.0 mM while the isolated alkaloids sophaline B and sophaline D significantly repressed the secretion of the HBsAg more than 50 percent.

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PMC11609529

These findings and those of others demonstrate that the YM fusion event represents a distinct mechanism for aberrant YAP1 signaling activation that drives tumor development and maintenance.

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PMC7192625

Results show combinations of 1 active and 1 repressive mark to be assortative in AND-ChAs but to have negative cross-ChAs.

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PMC8662250

We can hypothesize that the in vitro inhibitory propriety of CBD on CYP450 (Millar et al., 2019) may increase plasma concentrations of other medications.

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PMC11696659

Telomere analysis showed that patients in the cancer cohort had a higher proportion of short telomeres compared to the control cohort.

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PMC11754432

ALOX5 is known to be expressed in macrophages and neutrophils, and a faint band was present for ALOX5 for both keratinocytes and fibroblasts.

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PMC11806106

3Characterization of MOR BRET-based receptor conformation sensor.

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PMC8193813

The CO2-K30 sensor was measured to have a t95 response time at 6000 ppm CO2 of 9.0 ± 0.0s and a noise level of 1.6 ppm.

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PMC11794568

Existing melanoma treatments, such as immune checkpoint inhibitors and BRAF-targeted regimens, still suffer from problems such as drug resistance and side effects, although they have improved patient survival to some extent.

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PMC9429973

This year he presented with important lower and upper extremities edema, oliguria (1100ml / 24h), minor increase of lymph nodes and spleen; laboratory test showed: haemoglobin: 11.4 g / dl, white blood cells: 186.020 / mm3, platelet count 207.000 / mm3, urea: 126 mg / dl, creatinine: 1.94 mg / dl; urinary protein excre...

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PMC3203927

A ratio of 1.8–2.1 was considered a “clean” sample and could be used in microarray experiments.

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PMC2118063

The cells were infected with a retrovirus that expressed puromycin and either of two siRNA for IRF8 or a nonreactive siRNA.

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PMC9429973

Individual patient datasets were used to plot Kaplan-Meier (KM) curves and calculate hazard ratios (HR) using Cox regression in R software.

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PMC10170482

Control cells were untreated.

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PMC11740207

For the negative marker for VSELSCs, we selected receptor-type tyrosine-protein phosphatase C (CD45 antigen) since it is commonly used by researchers (Lacombe et al., 1997; Kuruca et al., 2019; Filidou et al., 2023) and is part of the EuroFlow standardization for hematological probes (Van Dongen et al., 2012; Glier et ...

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PMC9429973

All responding pts except 1 remain on therapy (PVR responder discontinued due to death unrelated to study treatment).

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PMC9429973

Methods: We analyzed updated follow-up data on all patients (pts) treated within the LH-05 GATLA trial.

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PMC11055510

CCK8 analyzed the effect of miR-135a-3p interaction with IL1RAP on the proliferation of SKOV3 cells. (

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