OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11464982	Data on the chemical parameters of the food enzyme were provided for three batches used for commercialisation and two batches produced for the toxicological tests (Table 1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10812665	However, metabolism is a network with some major hubs (e.g., the tricarboxylic acid (TCA) cycle).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "m...
PMC9429973	In half of the cases there was coexistence of more than one microorganism at pulmonary level.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "half", "of", "the", "cases", "there", "was...
PMC9429973	Hematological/non-hematological toxicity was acceptable in all groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hematological/non-hematological", "toxicity", "was", "acceptable", "in", "all", "groups", "." ] } ]
PMC11190062	Proliferation was assessed by quantification of cells in cell cycle S-phase, measured as 5-bromo-2′-deoxyuridine (BrdU)-positive live cells using flow cytometry.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Proliferation", "was", ...
PMC11593031	In conclusion, the present study demonstrates that using the Neuro-2a cell line as a murine model of NB is justified.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "conclusi...
PMC10936243	The pilot test indicated that a clear definition of SOP should be provided in the early stages of the questionnaire.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "pilot", "test", ...
PMC11737091	Therefore, new biomarkers to diagnose ccRCC in its early stages and develop new potential molecular therapeutic targets are urgently needed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", ...
PMC9164404	Differences were considered statistically significant at a level of p < 0.05; p < 0.01; p < 0.001; **p < 0.0001.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11319300	The homologous sequences include 16 mammals, including four primates, and chicken.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "homologous", "sequences", "include", "16", "mammals", ",", "includin...
PMC11512230	Although such an effect was seen in up to 5–8% of target cells, the tumor-penetrating ability can be increased by retargeting AltMV SPV to an alternative receptor such as neuropeptide Y1 , IGF-1R , or unknown surface proteins detected in our earlier investigation .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11650848	We have confirmed here the presence of the alternative transcript upstream of the original RefSeq ZFP57 transcript using a neuroblastoma cell line.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O" ], "tokens": ...
PMC9219615	Together, this information suggests that ERK activity contributes to the G2/M phase-dependent apoptosis (Figure 4) and microtubule/spindle disruption (Figure 6 and Figure 7) we observed after exposing cells to Tpz-1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11772585	Another study has demonstrated that inhibiting METTL1 and WDR4 globally can suppress m7G tRNA modification, resulting in hindered HCC progression .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Another", "s...
PMC11632064	This analysis shows that most proteins encoded by the signature are part of a tight interaction network that parallels functional classification analyses, such as mitochondrial central dogma, mitochondrial metabolism, OXPHOS, and apoptosis (Fig 7G).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9368503	Integrating these cell line proteomic data with the cohort of 36 patients across 4336 proteins shows that the three synovial sarcoma cell lines cluster closely together with the synovial sarcoma patient specimens, but separate from the three other histological subtypes (leiomyosarcoma, dedifferentiated liposarcoma, and...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10808409	This in turn, allows the micelles to circulate for a longer time.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "in", "turn", ",", "allows", "the", "micelles", "to", "circula...
PMC8389560	This indicates the pro-apoptotic action of SeNP, including through an alternative signaling cascade.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "indicates", "the", "pro-apoptotic", "action", "of", "SeNP", ...
PMC10788478	Survival curves were estimated by the Kaplan–Meier method.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Survival", "curves", "were", "estimated", "by", "the", "Kaplan", "–", "Meier", "method", "...
PMC10831439	The remaining α-GalCer-loaded autologous feeder cells were cryopreserved for later (CAR)-iNKT-cell expansion.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "remaining", "α-GalCer-loaded", "autologous", "feeder", "cells", "were", "cryopr...
PMC11585254	It is emerging that the extent to which β-arrestins can perform these three functions can be GPCR-specific or even ligand-specific, acting at the same GPCR (Maharana et al., 2022; Shukla et al., 2008).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11271278	Besides are the expression levels for the highlighted gene in all CCLE cell lines (violin plot), the trans-enhancer hijacking cell line (red), and other cell lines of the same lineage (blue).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7189327	The available microarray datasets for BCC were obtained from the Gene Expression Omnibus (GEO) database, and differentially expressed genes (DEGs) were identified between BCC and healthy controls.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11705547	Lipid metabolism, particularly fatty acid (FA) synthesis, is crucial for cell membrane biosynthesis, production of signaling molecules, and energy storage .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10631132	Both fibroblast and PBMC-derived iPSC lines showed multiple large spread-out multinucleated cells when differentiated according to the EB protocol (Fig. 5A,B,E,F).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11741577	Reverse transcription-quantitative PCR analysis of the expression of growth factors, including IGFBP2 (black), SCFR (green), PDGFA (blue), and VEGF-A (red), after cytokine array analysis (n = 4).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9243326	Then, we conducted a systematic analysis of all sequences, including functional annotation and identification of simple sequence repeats (SSRs), coding DNA sequences (CDSs), non-coding RNAs (ncRNAs), transcription factors (TFs), and alternative splicing (AS) events.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11549062	However, the expressions of above proteins were significantly decreased in the group of ApoE mice fed with a western diet and KY226 (Figure 6A–E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10899471	Further computational algorithms and dual-luciferase reporter assays demonstrated that miR-939-3p repressed BATF2 expression via directly binding to its 3’ untranslated region (3’ UTR).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3995603	These changes were significantly ameliorated in the AC treatment group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "changes", "were", "significantly", "ameliorated", "in", "the", "AC", "treatment", "grou...
PMC10870498	The results suggested that SIRT7 co-located with KIF23 in HEK-293T cells (Fig. 4F).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "results", "suggested", "that", "SIR...
PMC11730311	Results are presented as mean of n = 2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", "are", "presented", "as", "mean", "of", "n", "=", "2", "." ] } ]
PMC11634027	A-H) Abdomens of flies fed dye to mark the hindgut. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A-H", ")", "Abdomens", "of", "flies", "fed", "dye", "to", "mark", "the", ...
PMC10170482	Such quantitative confocal fluorescent imaging was shown to be a reliable measure for mitochondrial ROS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Such", "quantitative", "confocal", "fluorescent", "imaging", "was...
PMC10380508	PAX8 has also been shown to transcriptionally activate (E2F transcription factor 1) E2F1 expression, and hence the cell cycle, in RCC cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11075223	30 mg/kg, 100 mg/kg) exerted the anti-inflammatory activity by inhibiting asthma response and repressing NF-kappa B (NF-κB) phosphorylation, specific immunoglobulin E and Matrix Metalloproteinase 9 (MMP-9) expression in an allergic airway inflammation model .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6684588	Weight of ACE-083-injected, vehicle-injected, and uninjected (contralateral) TA muscles in wild-type and mdx mice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Weight", "of", "ACE-083-injected", ",", ...
PMC9429973	HSC viability after storage at -80ºС with 5% final DMSO concentration is very good and is not affected by higher cell packing thus allowing the reduction of infused DMSO and the side effects (cardiac, neurologic, respiratory, etc.)	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11792888	Effect of R. junceus scorpion venom on the cell cycle in non-cancerous and cancerous cells. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Effect", "of", "R.", "junceus", "scorpion", "venom", ...
PMC11680578	Percent alteration in the cell cycle in control and combination treatment of PTX and RGZ groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Percent", "alteration", "in", "the", "cell", "cycle", ...
PMC9352806	Studies have reported that the overall abundance of PE is critical for PE-lipidation of LC3/Atg8 and could thus regulate autophagosomal membrane formation (Rockenfeller et al., 2015).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11740907	The LE (%) was computed by dividing the difference by the total weight of SLNs using the given calculations. [	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "LE", ...
PMC8143558	Saponins are active against various types of fungi, including commercially important yeasts.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Saponins", "are", "active", "against", "various", "types", "of", "fungi", ...
PMC11743975	This optogenetics-based mitochondrial aggregation system (Opto-MitoA) is based on blue-light-induced homo-oligomerization of CRY2clust (Park et al., 2017) and simultaneous hetero-dimerization between the CRY2clust and CIBN (Figure 1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11591038	The half-life of HIF-1α in living cells under normoxic condition is only minutes .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "half-life", "of", "HIF-1α", "in", "living", "cells", "under", ...
PMC11755624	Psoriasis is classified as an inflammatory disease in which the dysregulation of the immune response plays a key role.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Psoriasis", "is", "classified", "...
PMC9545714	Subjects' photographs were obtained with the use of VISIA Evolution photography device.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Subjects", "'", "photographs", "were", "obtained", "with", "the", "use", ...
PMC9621239	Approximately 257 million people worldwide and approximately 70 million in China are chronically infected with HBV.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Approximately", "257", "million", "people", "worldwide", ...
PMC9436459	shalun ; M. bombycis ; M. macroura ; M. mongolica ; M. nigra ; M. notabilis ; S. bonplandii ; S. ilicifolia Kuwanon J 2,4,10"-trimethyl ether (82) + 102.5 M. alba Kuwanon Q (83) + 161 M. alba ; M. bombycis Artonin C (84) + 20 A. heterophyllus Artonin X (85) + 12 A. heterophyllus Kuwanon R (86) + 56 A. heterophyllus ; M...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11806106	The intracellular loop of the MOR consists out of five amino acids (R-M-L-S-G).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "intracellular", "loop", "of", "the", "MOR", "consist...
PMC10538569	Population count of total cells sorted and counts of expression for GFP positive, double positive (DP), DiD positive, or double negative (DN) populations and relative percent. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10745221	Each reaction mixture contained 33.3% (v/v) cell lysate, 50 mM HEPES pH = 9.0 (9.5 for PRMT7), 1 mM DTT, and 0.14 μM S-adenosyl-ʟ-[methyl-H] methionine ([H]AdoMet; Catalog No. NET155H001MC, PerkinElmer Life Sciences; 81.9 Ci/mmol, 7 μM in 9:1 10 mM H2SO4:ethanol).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9250505	The association of phosphorylated (p) BADS99 with clinicopathological parameters and survival outcomes in an EOC cohort was assessed by immunohistochemistry.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "assoc...
PMC11451940	After each time period, the cells were detached, harvested, washed twice with PBS (0.1 M, pH 7.4) and isolated by centrifugation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10237474	Although widely characterized, the overall timeline is a few months longer than that of the PB-based CHO stable pools.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Although", "widely", "charac...
PMC11371747	Representative figure out of three separate experiments is shown (SEM was within the size of the marker). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Representative", "figure", "...
PMC9429973	pneumoniae.	[ { "tags": [ "O", "O" ], "tokens": [ "pneumoniae", "." ] } ]
PMC3035438	The expression of chimeric ch/hu-IgHG1 in the CX13 culture supernatant was confirmed by western blotting (Figure 2C, lane 3), but the corresponding band appeared at a higher position than expected compared to the control human IgHG1 (lane 1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11637276	Cells were incubated with the extraction buffer (20 mM NH4OH and 0.5% triton X-100 in PBS) for 2 to 5 min at room temperature until no visible cells remained.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11612508	Fig.1The schematic of magnetic microspheres and drug release under a magnetic field.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.1The", "schematic", "of", "magnetic", "microspheres", "and", "drug", "release", ...
PMC11495567	FACS analysis showed the apoptotic potential of the PCAIs on the lung cancer cells indicating that the mechanism of PCAIs-induced cell death in NCI-H23 cells is by early apoptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", ...
PMC11321678	All qPCR were repeated three times.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "qPCR", "were", "repeated", "three", "times", "." ] } ]
PMC7961460	Although the primary sequence of c10orf118 contains a KDEL signal at position 677–680, compatible with the retention in the ER, confocal images revealed a preferential localization in the Golgi apparatus (Pearson’s Correlation = 0.7011 and 0.3804 in Golgi and ER, respectively).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The primary endpoint was overall survival (OS).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "primary", "endpoint", "was", "overall", "survival", "(", "OS", ")", "." ] } ]
PMC11365427	After one week of MM modelling, treatments were administered until the endpoints of the experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "one", "week", "of", "MM", "modelling", ...
PMC11754094	HEK3 +2GtoC epegRNA and FANCF 5–7del epegRNA were used in this figure.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HEK3", "+", "2GtoC", "epegRNA", "and", "FANCF", "5–7del", "epegRNA", ...
PMC11342785	Variants that could bundle MTs in vitro but showed poor activity in the OptoDroplets assay triggered limited bundling activity (e.g. N-CORE) (Figs. 3C, 6F and S9, D–F).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10291556	Additionally, the investigated Pt(IV) complexes selectively induce cell death in cancer cells, and the Pt(IV) complexes containing DCF ligands induce hallmarks of immunogenic cell death in cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11641630	In a second set of experiments, we performed transwell invasion assays to evaluate the invasive capacity of malignant cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "a", "second", "s...
PMC9429973	E. Arnault Carneiro, B. Ferreira, C. Pestana, F. Barahona, J. Caetano, R. Lopes, P. Lúcio, M. Neves, H. C. Beck, A. S. Carvalho, R. Matthiesen, B. Costa-Silva, C. João Myeloma Lymphoma Research Group, Champalimaud Foundation, Lisbon; Hemato-Oncology Unit, Champalimaud Foundation, Odense; NOVA Medical School, NOVA Medic...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The frequency of occurrence of BCL-2+ cells above the threshold level was detected statistically significantly more often in patients with frontline treatment failures of in relation to patients with CR: 17 (81%) versus 4 (19%) patients (p<0.001).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11422497	The expression of circ_SMA4 (F), miR-494-3p (G) and KIT mRNA (H) in Xenograft tumors were detected by RT-qPCR assay.n = 3. *	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Summary/Conclusion: We demonstrate that dual CD19/22 targeting CAR T cells generated by co-transduction show an acceptable safety profile, with robust expansion/persistence and early efficacy in a heavily pre-treated cohort.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10698968	Both migratory and invasive potentials have also been evaluated for some other MFS cell lines; the overall data reflect the high infiltrative nature of MFS that is well recreated by the majority of MFS cell lines [12, 21, 22, 35–38].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10747139	In vivo, toxicological experiments showed that 20 and 22 demonstrated the most zebrafish embryo developmental toxicity (inhibition of spontaneous movements and heartbeats), whereas 21 revealed the lowest toxicity; thus, complex 21, bearing the triphenylphosphino moiety, was suggested as the most promising candidate for...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11264242	While FYN is known to promote cellular proliferation and migration in multiple types of cancer (Peng and Fu, 2023), our findings reveal that SS18-SSX exerts a negative effect on FYN expression, at least in part, by repressing FYN transcription.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10847511	A higher AUC value of a sample indicates higher resistance to the assay.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "higher", "AUC", "value", "of", "a", "sample", "indicates", "high...
PMC3681794	However the degree to which they are dependent on functional HIF-1 is often uncertain.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", "the", "degree", "to", "which", "they", "are", "depend...
PMC4659567	The second sets of the signals attributable to the naza and p-cymene ligands, which revealed at 7.75/5.78/5.49 ppm (for 2) and 7.48/5.99/5.87 ppm (for 8), may be associated with the formation of decomposition products, probably connected with the solvolysis (substitution of the chlorido ligand(s) with DMF).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11482552	Methods: Jurkat cell line samples were counted using both a Thoma cell-counting chamber and Fluorescence-Activated Cell Sorting (FACS).	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Methods", ":",...
PMC10158546	ReN cells express markers of neurons (TUBB3) and astrocytes (GFAP), neural progenitors (NES) and PrP throughout standard differentiation.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC8389560	This ultimately led to the induction of apoptosis in these cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "ultimately", "led", "to", "the", "induction", "of", "apoptosis", "in", "these...
PMC6160470	are representative of 2 independent experiments performed in duplicates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "are", "representative", "of", "2", "independent", "experiments", "performed", "in", "duplicates", "." ]...
PMC11718109	This finding opens the possibility of using iPSC-derived DA neurons as a synaptic model to gain new insight into the still open question of how DA neurons regulate neurotransmitter release in nerve terminals, which are predominantly comprised of non-classical synapses.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11127909	To investigate whether the EFHD1 expression levels were associated with chemoresistance in OS cell lines, we first assessed endogenous EFHD1 expression in four OS cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8469018	The cellular thiols, such as reduced glutathione (GSH) are involved in many processes in cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cellular", "thiols", ",", "such...
PMC10969097	Additionally, they found higher serum levels of cytokines such as interleukin (IL) 1ra (associated with a better prognosis), IL 5 and IL 7 (can be interpreted as a positive effect of the treatment) compared to those who received a placebo.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10932641	Ki67 is a proliferation-related protein whose function is closely related to mitosis and is indispensable in cell proliferation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ki67", "is", "a", "proliferation-related", ...
PMC11012313	Early on, during active viral replication, viruses need to promote the replication of their genome as well as induce viral protein production, which requires the generation of not only energy but metabolic by-products that serve as a source of amino acids and nucleotides .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Data from a hospital Registry project were used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "from", "a", "hospital", "Registry", "project", "were", "used", "." ] } ]
PMC11464609	Metagenomics has been evaluated in cerebrospinal fluid , but depending on the spatial dynamics of CNS infections, viral nucleic acids might only be detectable in brain tissue specimens .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9352806	Fig. 5BMS decreased OA-induced fat deposition in HepG2 cell via inducing autophagy. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "5BMS", "decreased", "OA-induced", "fat", "deposition", "in", ...
PMC9429973	From there, we took further analysis on survival data with GSE16131.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "From", "there", ",", "we", "took", "further", "analysis", "on", "survival", ...
PMC9429973	Image: Summary/Conclusion: Mutal reactions between sirtuins and miRNAs may influence the hematopoietic landscape during HSC mobilization and differ depending on the depth of myeloma/lymphoma response.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9812014	HHT treatment of PEDV-infected Vero cells showed reduced viral loads at a concentration of 200 nM, and at 500 nM HHT concentration the infection was completely suppressed.	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	A. Åkesson, J. B. Bussel, M. Martin, A. M. Blom, J. Klintman, W. Ghanima, E. Zetterberg, L. Garabet Lund University, Malmö, Sweden; Cornell University, New York, United States of America; Østfold Hospital, Grålum; Akershus University Hospital, Lørenskog, Norway Background: Increased platelet destruction is central in t...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11779605	This lack of significant differences in patient and tumor demographics indicates that the differences in survival between FGF7 low- and high-expressing groups are not due to any of these parameters. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Image: Summary/Conclusion: These functional subsets of BMPCs provide mechanistic insights into AL pathogenesis, light chain production, and chemotherapy response.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Image",...
PMC11591038	It was also revealed with resting-state functional MRI that hypoperfusion may contribute to cognitive impairment via abnormal brain functional connectivity .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "was", "also", "r...
PMC11394386	Subsequently, the nuclei were stained with Hoechst at a 1:3000 dilution (YB2820692).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Subsequently", ",", "the", "nuclei", "were", "stained", "wi...

PMC11464982

Data on the chemical parameters of the food enzyme were provided for three batches used for commercialisation and two batches produced for the toxicological tests (Table 1).

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PMC10812665

However, metabolism is a network with some major hubs (e.g., the tricarboxylic acid (TCA) cycle).

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PMC9429973

In half of the cases there was coexistence of more than one microorganism at pulmonary level.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "half", "of", "the", "cases", "there", "was...

PMC9429973

Hematological/non-hematological toxicity was acceptable in all groups.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hematological/non-hematological", "toxicity", "was", "acceptable", "in", "all", "groups", "." ] } ]

PMC11190062

Proliferation was assessed by quantification of cells in cell cycle S-phase, measured as 5-bromo-2′-deoxyuridine (BrdU)-positive live cells using flow cytometry.

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PMC11593031

In conclusion, the present study demonstrates that using the Neuro-2a cell line as a murine model of NB is justified.

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PMC10936243

The pilot test indicated that a clear definition of SOP should be provided in the early stages of the questionnaire.

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PMC11737091

Therefore, new biomarkers to diagnose ccRCC in its early stages and develop new potential molecular therapeutic targets are urgently needed.

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PMC9164404

Differences were considered statistically significant at a level of *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.

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PMC11319300

The homologous sequences include 16 mammals, including four primates, and chicken.

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PMC11512230

Although such an effect was seen in up to 5–8% of target cells, the tumor-penetrating ability can be increased by retargeting AltMV SPV to an alternative receptor such as neuropeptide Y1 , IGF-1R , or unknown surface proteins detected in our earlier investigation .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11650848

We have confirmed here the presence of the alternative transcript upstream of the original RefSeq ZFP57 transcript using a neuroblastoma cell line.

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PMC9219615

Together, this information suggests that ERK activity contributes to the G2/M phase-dependent apoptosis (Figure 4) and microtubule/spindle disruption (Figure 6 and Figure 7) we observed after exposing cells to Tpz-1.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11772585

Another study has demonstrated that inhibiting METTL1 and WDR4 globally can suppress m7G tRNA modification, resulting in hindered HCC progression .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Another", "s...

PMC11632064

This analysis shows that most proteins encoded by the signature are part of a tight interaction network that parallels functional classification analyses, such as mitochondrial central dogma, mitochondrial metabolism, OXPHOS, and apoptosis (Fig 7G).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9368503

Integrating these cell line proteomic data with the cohort of 36 patients across 4336 proteins shows that the three synovial sarcoma cell lines cluster closely together with the synovial sarcoma patient specimens, but separate from the three other histological subtypes (leiomyosarcoma, dedifferentiated liposarcoma, and...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10808409

This in turn, allows the micelles to circulate for a longer time.

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PMC8389560

This indicates the pro-apoptotic action of SeNP, including through an alternative signaling cascade.

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PMC10788478

Survival curves were estimated by the Kaplan–Meier method.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Survival", "curves", "were", "estimated", "by", "the", "Kaplan", "–", "Meier", "method", "...

PMC10831439

The remaining α-GalCer-loaded autologous feeder cells were cryopreserved for later (CAR)-iNKT-cell expansion.

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PMC11585254

It is emerging that the extent to which β-arrestins can perform these three functions can be GPCR-specific or even ligand-specific, acting at the same GPCR (Maharana et al., 2022; Shukla et al., 2008).

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PMC11271278

Besides are the expression levels for the highlighted gene in all CCLE cell lines (violin plot), the trans-enhancer hijacking cell line (red), and other cell lines of the same lineage (blue).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7189327

The available microarray datasets for BCC were obtained from the Gene Expression Omnibus (GEO) database, and differentially expressed genes (DEGs) were identified between BCC and healthy controls.

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PMC11705547

Lipid metabolism, particularly fatty acid (FA) synthesis, is crucial for cell membrane biosynthesis, production of signaling molecules, and energy storage .

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PMC10631132

Both fibroblast and PBMC-derived iPSC lines showed multiple large spread-out multinucleated cells when differentiated according to the EB protocol (Fig. 5A,B,E,F).

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PMC11741577

Reverse transcription-quantitative PCR analysis of the expression of growth factors, including IGFBP2 (black), SCFR (green), PDGFA (blue), and VEGF-A (red), after cytokine array analysis (n = 4).

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PMC9243326

Then, we conducted a systematic analysis of all sequences, including functional annotation and identification of simple sequence repeats (SSRs), coding DNA sequences (CDSs), non-coding RNAs (ncRNAs), transcription factors (TFs), and alternative splicing (AS) events.

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PMC11549062

However, the expressions of above proteins were significantly decreased in the group of ApoE mice fed with a western diet and KY226 (Figure 6A–E).

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PMC10899471

Further computational algorithms and dual-luciferase reporter assays demonstrated that miR-939-3p repressed BATF2 expression via directly binding to its 3’ untranslated region (3’ UTR).

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PMC3995603

These changes were significantly ameliorated in the AC treatment group.

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PMC10870498

The results suggested that SIRT7 co-located with KIF23 in HEK-293T cells (Fig. 4F).

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PMC11730311

Results are presented as mean of n = 2.

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PMC11634027

A-H) Abdomens of flies fed dye to mark the hindgut. (

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PMC10170482

Such quantitative confocal fluorescent imaging was shown to be a reliable measure for mitochondrial ROS.

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PMC10380508

PAX8 has also been shown to transcriptionally activate (E2F transcription factor 1) E2F1 expression, and hence the cell cycle, in RCC cells .

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PMC11075223

30 mg/kg, 100 mg/kg) exerted the anti-inflammatory activity by inhibiting asthma response and repressing NF-kappa B (NF-κB) phosphorylation, specific immunoglobulin E and Matrix Metalloproteinase 9 (MMP-9) expression in an allergic airway inflammation model .

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PMC6684588

Weight of ACE-083-injected, vehicle-injected, and uninjected (contralateral) TA muscles in wild-type and mdx mice.

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PMC9429973

HSC viability after storage at -80ºС with 5% final DMSO concentration is very good and is not affected by higher cell packing thus allowing the reduction of infused DMSO and the side effects (cardiac, neurologic, respiratory, etc.)

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PMC11792888

Effect of R. junceus scorpion venom on the cell cycle in non-cancerous and cancerous cells. (

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PMC11680578

Percent alteration in the cell cycle in control and combination treatment of PTX and RGZ groups.

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PMC9352806

Studies have reported that the overall abundance of PE is critical for PE-lipidation of LC3/Atg8 and could thus regulate autophagosomal membrane formation (Rockenfeller et al., 2015).

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PMC11740907

The LE (%) was computed by dividing the difference by the total weight of SLNs using the given calculations. [

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PMC8143558

Saponins are active against various types of fungi, including commercially important yeasts.

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PMC11743975

This optogenetics-based mitochondrial aggregation system (Opto-MitoA) is based on blue-light-induced homo-oligomerization of CRY2clust (Park et al., 2017) and simultaneous hetero-dimerization between the CRY2clust and CIBN (Figure 1).

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PMC11591038

The half-life of HIF-1α in living cells under normoxic condition is only minutes .

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PMC11755624

Psoriasis is classified as an inflammatory disease in which the dysregulation of the immune response plays a key role.

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PMC9545714

Subjects' photographs were obtained with the use of VISIA Evolution photography device.

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PMC9621239

Approximately 257 million people worldwide and approximately 70 million in China are chronically infected with HBV.

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PMC9436459

shalun ; M. bombycis ; M. macroura ; M. mongolica ; M. nigra ; M. notabilis ; S. bonplandii ; S. ilicifolia Kuwanon J 2,4,10"-trimethyl ether (82) + 102.5 M. alba Kuwanon Q (83) + 161 M. alba ; M. bombycis Artonin C (84) + 20 A. heterophyllus Artonin X (85) + 12 A. heterophyllus Kuwanon R (86) + 56 A. heterophyllus ; M...

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PMC11806106

The intracellular loop of the MOR consists out of five amino acids (R-M-L-S-G).

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PMC10538569

Population count of total cells sorted and counts of expression for GFP positive, double positive (DP), DiD positive, or double negative (DN) populations and relative percent. (

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PMC10745221

Each reaction mixture contained 33.3% (v/v) cell lysate, 50 mM HEPES pH = 9.0 (9.5 for PRMT7), 1 mM DTT, and 0.14 μM S-adenosyl-ʟ-[methyl-H] methionine ([H]AdoMet; Catalog No. NET155H001MC, PerkinElmer Life Sciences; 81.9 Ci/mmol, 7 μM in 9:1 10 mM H2SO4:ethanol).

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PMC9250505

The association of phosphorylated (p) BADS99 with clinicopathological parameters and survival outcomes in an EOC cohort was assessed by immunohistochemistry.

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PMC11451940

After each time period, the cells were detached, harvested, washed twice with PBS (0.1 M, pH 7.4) and isolated by centrifugation.

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PMC10237474

Although widely characterized, the overall timeline is a few months longer than that of the PB-based CHO stable pools.

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PMC11371747

Representative figure out of three separate experiments is shown (SEM was within the size of the marker). (

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PMC9429973

pneumoniae.

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PMC3035438

The expression of chimeric ch/hu-IgHG1 in the CX13 culture supernatant was confirmed by western blotting (Figure 2C, lane 3), but the corresponding band appeared at a higher position than expected compared to the control human IgHG1 (lane 1).

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PMC11637276

Cells were incubated with the extraction buffer (20 mM NH4OH and 0.5% triton X-100 in PBS) for 2 to 5 min at room temperature until no visible cells remained.

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PMC11612508

Fig.1The schematic of magnetic microspheres and drug release under a magnetic field.

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PMC11495567

FACS analysis showed the apoptotic potential of the PCAIs on the lung cancer cells indicating that the mechanism of PCAIs-induced cell death in NCI-H23 cells is by early apoptosis.

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PMC11321678

All qPCR were repeated three times.

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PMC7961460

Although the primary sequence of c10orf118 contains a KDEL signal at position 677–680, compatible with the retention in the ER, confocal images revealed a preferential localization in the Golgi apparatus (Pearson’s Correlation = 0.7011 and 0.3804 in Golgi and ER, respectively).

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PMC9429973

The primary endpoint was overall survival (OS).

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PMC11365427

After one week of MM modelling, treatments were administered until the endpoints of the experiments.

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PMC11754094

HEK3 +2GtoC epegRNA and FANCF 5–7del epegRNA were used in this figure.

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PMC11342785

Variants that could bundle MTs in vitro but showed poor activity in the OptoDroplets assay triggered limited bundling activity (e.g. N-CORE) (Figs. 3C, 6F and S9, D–F).

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PMC10291556

Additionally, the investigated Pt(IV) complexes selectively induce cell death in cancer cells, and the Pt(IV) complexes containing DCF ligands induce hallmarks of immunogenic cell death in cancer cells.

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PMC11641630

In a second set of experiments, we performed transwell invasion assays to evaluate the invasive capacity of malignant cells.

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PMC9429973

E. Arnault Carneiro, B. Ferreira, C. Pestana, F. Barahona, J. Caetano, R. Lopes, P. Lúcio, M. Neves, H. C. Beck, A. S. Carvalho, R. Matthiesen, B. Costa-Silva, C. João Myeloma Lymphoma Research Group, Champalimaud Foundation, Lisbon; Hemato-Oncology Unit, Champalimaud Foundation, Odense; NOVA Medical School, NOVA Medic...

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PMC9429973

The frequency of occurrence of BCL-2+ cells above the threshold level was detected statistically significantly more often in patients with frontline treatment failures of in relation to patients with CR: 17 (81%) versus 4 (19%) patients (p<0.001).

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PMC11422497

The expression of circ_SMA4 (F), miR-494-3p (G) and KIT mRNA (H) in Xenograft tumors were detected by RT-qPCR assay.n = 3. *

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PMC9429973

Summary/Conclusion: We demonstrate that dual CD19/22 targeting CAR T cells generated by co-transduction show an acceptable safety profile, with robust expansion/persistence and early efficacy in a heavily pre-treated cohort.

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PMC10698968

Both migratory and invasive potentials have also been evaluated for some other MFS cell lines; the overall data reflect the high infiltrative nature of MFS that is well recreated by the majority of MFS cell lines [12, 21, 22, 35–38].

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PMC10747139

In vivo, toxicological experiments showed that 20 and 22 demonstrated the most zebrafish embryo developmental toxicity (inhibition of spontaneous movements and heartbeats), whereas 21 revealed the lowest toxicity; thus, complex 21, bearing the triphenylphosphino moiety, was suggested as the most promising candidate for...

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PMC11264242

While FYN is known to promote cellular proliferation and migration in multiple types of cancer (Peng and Fu, 2023), our findings reveal that SS18-SSX exerts a negative effect on FYN expression, at least in part, by repressing FYN transcription.

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PMC10847511

A higher AUC value of a sample indicates higher resistance to the assay.

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PMC3681794

However the degree to which they are dependent on functional HIF-1 is often uncertain.

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PMC4659567

The second sets of the signals attributable to the naza and p-cymene ligands, which revealed at 7.75/5.78/5.49 ppm (for 2) and 7.48/5.99/5.87 ppm (for 8), may be associated with the formation of decomposition products, probably connected with the solvolysis (substitution of the chlorido ligand(s) with DMF).

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PMC11482552

Methods: Jurkat cell line samples were counted using both a Thoma cell-counting chamber and Fluorescence-Activated Cell Sorting (FACS).

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PMC10158546

ReN cells express markers of neurons (TUBB3) and astrocytes (GFAP), neural progenitors (NES) and PrP throughout standard differentiation.

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PMC8389560

This ultimately led to the induction of apoptosis in these cells.

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PMC6160470

are representative of 2 independent experiments performed in duplicates.

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PMC11718109

This finding opens the possibility of using iPSC-derived DA neurons as a synaptic model to gain new insight into the still open question of how DA neurons regulate neurotransmitter release in nerve terminals, which are predominantly comprised of non-classical synapses.

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PMC11127909

To investigate whether the EFHD1 expression levels were associated with chemoresistance in OS cell lines, we first assessed endogenous EFHD1 expression in four OS cell lines.

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PMC8469018

The cellular thiols, such as reduced glutathione (GSH) are involved in many processes in cells.

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PMC10969097

Additionally, they found higher serum levels of cytokines such as interleukin (IL) 1ra (associated with a better prognosis), IL 5 and IL 7 (can be interpreted as a positive effect of the treatment) compared to those who received a placebo.

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PMC10932641

Ki67 is a proliferation-related protein whose function is closely related to mitosis and is indispensable in cell proliferation.

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PMC11012313

Early on, during active viral replication, viruses need to promote the replication of their genome as well as induce viral protein production, which requires the generation of not only energy but metabolic by-products that serve as a source of amino acids and nucleotides .

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PMC9429973

Data from a hospital Registry project were used.

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PMC11464609

Metagenomics has been evaluated in cerebrospinal fluid , but depending on the spatial dynamics of CNS infections, viral nucleic acids might only be detectable in brain tissue specimens .

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PMC9352806

Fig. 5BMS decreased OA-induced fat deposition in HepG2 cell via inducing autophagy. (

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PMC9429973

From there, we took further analysis on survival data with GSE16131.

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PMC9429973

Image: Summary/Conclusion: Mutal reactions between sirtuins and miRNAs may influence the hematopoietic landscape during HSC mobilization and differ depending on the depth of myeloma/lymphoma response.

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PMC9812014

HHT treatment of PEDV-infected Vero cells showed reduced viral loads at a concentration of 200 nM, and at 500 nM HHT concentration the infection was completely suppressed.

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PMC9429973

A. Åkesson, J. B. Bussel, M. Martin, A. M. Blom, J. Klintman, W. Ghanima, E. Zetterberg, L. Garabet Lund University, Malmö, Sweden; Cornell University, New York, United States of America; Østfold Hospital, Grålum; Akershus University Hospital, Lørenskog, Norway Background: Increased platelet destruction is central in t...

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PMC11779605

This lack of significant differences in patient and tumor demographics indicates that the differences in survival between FGF7 low- and high-expressing groups are not due to any of these parameters. (

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PMC9429973

Image: Summary/Conclusion: These functional subsets of BMPCs provide mechanistic insights into AL pathogenesis, light chain production, and chemotherapy response.

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PMC11591038

It was also revealed with resting-state functional MRI that hypoperfusion may contribute to cognitive impairment via abnormal brain functional connectivity .

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PMC11394386

Subsequently, the nuclei were stained with Hoechst at a 1:3000 dilution (YB2820692).

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