OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11745600	Red, Porcine C-peptide (INS); green, porcine GCG.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Red", ",", "Porcine", "C-peptide", "(", "INS", ")", ";", "green", ",", ...
PMC9429973	The control group** were matched patients treated by chemotherapy or immunechemotherapy previously in Beijing Chaoyang Hospital.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "control", "group", "", "", ...
PMC10547921	Therefore, one of the focuses of immunotherapy research and development is to develop anti-cancer therapies that can stimulate the patients’ innate immune response and promote tumor-specific T cell recruitment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10376064	However, although water and subsequent DMF uptake were documented for both female and male (slightly reduced) mice, DMF did not improve β-amyloidosis in agreement with our previous study .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10999934	In fact, it has been well established that epithelial cells are the targets of chemotherapy in HGSOC .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "fact", ",", "it", "has", "...
PMC11792090	Upregulation of CD107a levels of NK cells following co-culture with various CAR-T cells. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Upregulation", "of", "CD107a", "levels", "of", "NK", "cells", "f...
PMC11422150	therefore suppressing the immune response of the host (Veglia et al., 2018).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "therefore", "suppressing", "the", "immune", "response", "of", ...
PMC11806106	We then calculated the IC50 for naloxone with 2.7 nM and the Ki with 1.1 nM, in line with the literature.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "then",...
PMC11514418	For the immune system, APS was identified as a multiple immune activator, which can stimulate the maturation and antigen presentation of IL-12-producing dendritic cells (DCs) and then activate T cells by interacting with anti-TLR4 on CD4+ CD25+ Treg cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11317131	Cells plated on arabinose form smaller, slower growing colonies than when plated on glucose due to the mutagenesis activity of a functional (arabinose sensitive) MP (45).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7887261	To test whether knockdown or overexpression of the candidate genes or variants induces endogenous DNA damage, we performed flow cytometric assays to measure γH2AX levels, a DNA double-strand-break marker, following siRNA knockdown and overproduction of GFP fusions of proteins of interest.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3730428	To further prove that it is FLIP's recruitment to complex IIb that modulates sensitivity to AT-IAP/TNFα, we utilized a FLIP mutant (F114A) that cannot interact with the critical adapter protein in the complex, FADD (Figure 4c).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9164404	Abplatin could be accumulated at the tumor site via blood circulation and internalized by the cancer cells via endocytosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Abplatin", "could", "be", "accumu...
PMC10589262	To investigate whether Golgi-retained MT-KIT primarily contributes to downstream oncogenic signaling activation, we investigated the interaction of MT-KIT with P85 and GRB2, the upstream effectors of the PI3K/AKT and MAPK/ERK pathways, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11489351	A, schematic of Notch1 signaling reporter used to quantify Notch1 activity in single cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", ",", "schematic", "of", "Notch1", "signaling", "reporte...
PMC11365983	After 5 days in culture, samples were fixed in Dent’s solution and immunofluorescently labelled with anti-Arl13b and anti-γ-tubulin antibodies (see Supplemental methods for details).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11770746	Despite the proven efficacy of platinum drugs in treating various cancers, severe side effects accompany the oncological treatments, including peripheral neuropathy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Despite...
PMC11525028	Primers were listed in Table S8.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Primers", "were", "listed", "in", "Table", "S8", "." ] } ]
PMC9429973	Results: After the intervention, the CFS scale score of patients in the control group was lower than that in the observation group (P<0.05), and the HAMD score and HAMA score were lower than those in the observation group (P<0.05).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11721587	Upon Hh stimulation, the Hh signal transducer Smoothened (Smo) interacts with Cos2 and PKA to inhibit Ci processing (13, 16–21).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10761218	Cell morphology revealed significant morphological changes in HepG2 and L929 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O" ], "tokens": [ "Cell", "morphology", "revealed", "significant", "morphological", "changes", "in", ...
PMC11599565	The clusters of OC cells maintained in organoid conditions revealed that in the early stages, these cells develop a neuronal appearance similar to 2D models (A-E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9424261	Cells were cultured in Dulbecco’s modified Eagle’s medium (DMEM, HyClone, Logan, UT, USA) supplemented with 1% penicillin–streptomycin and 10% fetal bovine serum (FBS, Gibco, Carlsbad, CA, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7925574	A Welch two sample T-test showed significantly (p < 0.05, p < 0.01 and **p < 0.001) higher E1A expression levels in 293-F compared to Freestyle 293-F and 293-H, whereas E1B was significantly higher in HEK293, 293E and 293-H cell lines compared to others.”	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9275501	Many natural active ingredients, such as berberine (BER) (Coelho et al., 2017; Wu et al., 2019b), EGCG (Cheng et al., 2016), honokiol (Huang et al., 2017; Pillai et al., 2017; Huang et al., 2020), RES (Gu et al., 2018), glycyrrhizin (GL) (Figure 1) (Lv et al., 2020), Que (Chen et al., 2019) and Sch B (Thandavarayan et ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7802142	Using Bowtie software, the clean reads were compared with Silva database, GtRNAdb database, Rfam database and Repbase database sequence alignment to filter ribosomal RNA(rRNA), transfer RNA (tRNA), small nuclear RNA (snRNA), small nucleolar RNA (snoRNA)and other ncRNA and repeats.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11694066	P < 0.01; ns, not significant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P", "<", "0.01", ";", "ns", ",", "not", "significant", "." ] } ]
PMC11705862	Informed consent for the use of brain tissue, plasma, and clinical data for research purposes were obtained from all subjects or their legal representatives in accordance with the International Declaration of Helsinki .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11371627	Overview of XK pathophysiology and clinical manifestation in our patient. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Overview", "of", "XK", "pathophysiology", "and", "clinical", "manifestation", "in", "our", ...
PMC6364197	Hematopoietic stem cell transplantation is the only way to cure leukemia.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hematopoietic", "stem", "cell", "transplantation", "is", "the", "only", "way", "to", ...
PMC9587298	Elderberry fruits were exhaustively extracted to obtain all extractable polyphenols, as reported by Ferreira, Silva, Silva, and Nunes (2020).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10976516	Enhanced tumor clearance compared with unarmed IVOVIR-15.Barlabé et al.Vesicular stomatitis virusRecombinant oncolytic vesicular stomatitis virus (VSV) pseudo-typed with LCMV-GP expressing tumor-associated antigens, termed VSV-GP-TAAIntravenous with KISIMA-TAA as a self-adjuvant cancer vaccine in combination with anti-...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10587429	With careful design and optimization, this model can be utilized for other pediatric and/or bone cancers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "With", "careful", "design", "and", "optimization"...
PMC11637276	SB203580 from Startech.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "SB203580", "from", "Startech", "." ] } ]
PMC11687663	The prominent molecular interaction includes; conventional hydrogen bond, pi-pi stacked, pi-alkyl, carbon-hydrogen bond, pi-loan pair and pi-pi T shaped bond.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	Twenty-eight patients from VHR group with sibling familial donor underwent allograft.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Twenty-eight", "patients", "from", "VHR", "group", "with", "sibling", "familial", "donor", ...
PMC8567602	B, Schematic of the expression and recombination pattern from Myf5Cre and a mouse with anatomic distribution of Myf5Cre; Smarcb1/fl and Myf5Cre;hSS2 tumors from 16 consecutive mice in each group (two-tailed Fisher exact test for incidence of tumors in each cohort, P = 0.0002; χ = 17.03 with four degrees of freedom and ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	These stresses result in ineffective erythropoiesis and shorten RBC lifespan, leading to chronic anemia.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "stresses", "result", "in", "ineffective", "erythropoiesi...
PMC11633763	The protein levels of β‐catenin and HK2 were assessed by western blotting in USP22‐overexpression U2OS cells following treatment with shβ‐catenin. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "protein...
PMC10713411	Figure 2C, 2D).	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Figure", "2C", ",", "2D", ")", "." ] } ]
PMC11765988	These factors are briefly analyzed.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "factors", "are", "briefly", "analyzed", "." ] } ]
PMC11779993	Epidermal cells are necessary to complete wound closure.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Epidermal", "cells", "are", "necessary", "to", "complete", "wound", "closure", "." ] } ]
PMC10818573	Instead of using a dedicated instrument to maintain the isothermal amplification of reactions, other more cost-effective instruments, such as constant temperature metal baths and boiling water baths, can be used, and human-generated heat has been demonstrated for the device-free amplification of HIV .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Among dead 106 patients were of thalassemia major, 16 thalassemia intermedia and 3 sickle cell anemia.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Among", "dead", "106", "patients", "were", ...
PMC11764090	Advances in plant multi-omics, such as genomics, transcriptomics, proteomics, microbial functional genomics, epigenetics, and metabolomics, have accelerated the discovery of the molecular mechanisms behind plant cold tolerance .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10900886	Error bars denote SEM.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Error", "bars", "denote", "SEM", "." ] } ]
PMC11656657	In selected experiment, PBMC alone or PBMC + 143B G-CSF cells were co-cultured with increasing doses of Human G-CSF, premium grade (Miltenyi; Catalog No: 130-096-347) (ranging from 0.5 to 50 ng/ml) for 72 h. At the end of the co-cultures MDSC were analyzed by flow cytometry.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11397654	However, a tendency of these superbase compounds to decompose in solution was also observed, which could pose significant challenges to their stability and practical application.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10253553	The 786-0 cell line also expressed high levels of high phospho-NDRG1 (Thr346) and total NDRG1 (Figure 2, Figure 3 and Figure 4), which is consistent with the clinical samples (Figure 1).	[ { "tags": [ "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC9429973	of Medicine 3, University Hospital Leverkusen, Leverkusen; Dept.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "of", "Medicine", "3", ",", "University", "Hospital", "Leverkusen", ",", "Leverkusen", ...
PMC10723784	There were more percentage of ovarian cancer cells in early apoptosis when treated with CBD as compared with those treated with CBG, which also correlates with the earlier results where CBD induced a stronger cytotoxicity compared to CBG.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11705862	Changes in mRNA expression levels for IRIS-1, 2 and CD59 were measured by semi-quantitative PCR performed on mRNA samples, as no specific probes with TaqMan detection system exist for IRIS-1 and 2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11342785	Related to (Fig. S5) N here refers to the number of cells on which the FRAP was performed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Related", "to", "(", "...
PMC11617590	Effects of sulforaphane on the expression of apoptosis‐related proteins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Effects", "of", "sulforaphane", "on", "the", "expression", "of", "apoptosis‐related", "proteins", "." ]...
PMC9812014	They exploit and take over the host’s cellular machinery, spreading throughout the organism .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "They", "exploit", "and", "take", "over", "the", "host", ...
PMC11518994	Whole-Transcriptome RNA-SEQ was negative to fusion genes in both patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Whole-Transcriptome", "RNA-SEQ", "was", "negative", "to", "fusion", "genes", "in", "both", "pati...
PMC11574271	Consistent with this observation, increased cell migration, and invasion were observed in cells treated with the hsa-miR-659-3p inhibitor, which can also be mitigated by specific RON inhibitor BMS-777607 (Fig. S3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11653533	Stem bark extracts of F. exasperata have shown antimicrobial effects against P. aeruginosa, S. typhi, K. pneumoniae, and S. aureus demonstrating respective inhibition zones of14.33 ± 0.33, 12.33 ± 0.33, 17.33 ± 0.67 and 15.0 ± 0.58 mm (Kingsley, 2013).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9878562	The results are in line with the in vitro observations indicating that LTB4/BLT1R signaling is required for cell-to-cell-induced migration.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "results", "are", "in", ...
PMC6892818	mCD40L caused marked cell death by 48 h (0.8:1 ratio) in all RCC lines, comparable to EJ (Fig. 2b), with similar observations at 72 h (Supplementary Fig. 1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11637284	The latter has two TMDs and its N- and C-termini face the cytosol .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "latter", "has", "two", "TMDs", "and", "its", "N-", "and", ...
PMC11424574	Colony formation efficiency (%) = (numbers of shMTA2 cell colonies/ number of shLuc cell colonies) × 100%.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "...
PMC9429973	The IL-35 receptors gp130 and IL-12Rβ were found to be expressed on human MKs, suggesting a role for IL-35 during megakaryopoiesis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "IL-35...
PMC11190062	Genes with logFC > 0 or logFC < 0 and −log10 (adj.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Genes", "with", "logFC", ">", "0", "or", "logFC", "<", "0", "an...
PMC11746948	The protein concentration in the supernatant was determined using the BCA Protein Assay Kit (Thermo Fisher Scientific, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "protein", ...
PMC11770130	Notably, a similar increase in food intake was also observed in Ntsr2 AKO mice kept in the thermoneutral condition (Supplementary information, Fig. S3d).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6835762	In particular, while C18 chains promote favorable interactions with DXMP, having too many C18 chains decreases solubility, preventing the polymer from interacting with surrounding DXMP molecules.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11319300	The human MYEOV-3′-putative enhancer was defined by active regions determined by ATAC-STAR-seq in GM12878, together with the presence of histone marks H3K27ac, H3K4me1 (with or without the presence of H3K4me3) and regions of DNase I hypersensitivity defined by DNase-seq.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11574029	M Transwell assay evaluating the invasion and migration abilities of T24 and 5637 cells after NOTCH3 knockdown.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O" ], "tokens": [ "M", "Transwell", "assay", "evaluating...
PMC11637284	The region mostly affected is indicated by broken lines in Fig 3B.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "region", "mostly", "affected", "is", "indicated", "by", "broken", "lines"...
PMC8633974	The funding authorities of this study did not participate in any part of the experimental design, execution, or data analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "fundi...
PMC11337594	We speculate that this is related to the period of Ki67 expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "speculate", "that", "this", "is", "related", "to", "the", "period", ...
PMC11334037	IGF2 was screened and analyzed using Gene Expression Omnibus (GEO: GSE225819) data.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "IGF2", "was", "screened", "and", "analyzed", "using", "Gene...
PMC11725127	LC–MS/MS analysis.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "LC", "–", "MS/MS", "analysis", "." ] } ]
PMC11799978	Cells were lysed on ice for 30 min with intermittent vertexing.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "lysed", "on", "ice", "for", "30", "min", "with", "intermittent", ...
PMC10994876	Correspondingly, the loss of PTEN due to the YAP overexpression led to an increase in mTOR expression, while the transcription level of S6K did not show any significant changes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9352806	Protein concentrations were determined by BCA assay kit (Nanjing Jiancheng Bioengineering Institute, Nanjing, China).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Protein", "concentrations", "were", "determi...
PMC10196713	no. A11034; Invitrogen; Thermo Fisher Scientific, Inc.) for 30 min at room temperature.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "no.", "A11034", ";", "Invitrogen", ";", "Th...
PMC11791203	Two-dimensional docking interaction images of 1,2-benzenedicarboxylic acid, Cyclododecanol, 2,4-Ditert-Butylphenol and Sulfurous acid, hexyl octyl ester onto Caspase 9 and (C) RC plot of 1,2-benzenedicarboxylic acid, Cyclododecanol, 2,4-Ditert-Butylphenol and Sulfurous acid, hexyl octyl ester onto Caspase 9.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9436459	Morusalbanol A (148) from M. alba, possessing the same 6-membered oxygen ring as 18 − 22, has cis–trans configuration.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11301242	Chromothripsis events were identified using ShatterSeek with SV and CN data (Supplementary Fig. 4A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Chromothripsis", "events", "were", "identified", "using", ...
PMC11699465	The concurrent work of our lab is to illustrate the role of TMEM199 in influencing PPI immunotherapy and then seek a replacement drug for the patients who accept immunotherapy and chemotherapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10380508	Furthermore, the PAXclusterA subtype was observed significantly more frequently in early-stage tumors: stage I and stage II (p < 0.001), grade 1 and grade 2 (p = 0.023), and T stage 1 (T1) and T stage 2 (T2) (p < 0.001).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11216402	By aggregating motif activity scores following pairwise comparisons between each Mes-like cell line and each ENCODE fibroblast, we rediscovered AP-1 and RUNX to be active in Mes-like GC as opposed to TWIST and ZEB being more active in normal fibroblasts (Fig. 7E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11359735	Left panel: the immunoprecipitate was analyzed by SDS-PAGE followed by fluorography.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Left", "panel", ":", "the", "immunoprecipitate", "was", "analyzed", "by", "SDS-P...
PMC9429973	BAT patients were most frequently treated with tyrosine kinase inhibitors (73 out of 121 LOTs, 60%) or cytoreductive therapies (46 out of 121 LOTs, 38%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9532503	The crosslinking of mAb and FcγR will stimulate ADCC which is based on the binding affinities of this interaction.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "crosslinking", "of", "mAb"...
PMC9684669	As revealed by these results, they indicated the CAMK2/CREB1 pathway was overactive in the A2780-ADR cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "As", "revealed", "by", "these", "results...
PMC10452486	Interestingly, the trophoblasts do not express HLA-A and HLA-B but only HLA-C, HLA-E, HLA-G , and HLA-F .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interestingly", ",", "the", ...
PMC9429973	In 5 pts, impeding relapse was predicted by a CH-associated mut MRD conversion with a median VAF of 0.27 (range 0.06-1.0)% at a median of 103 (range 14-199) days prior to relapse.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11746948	The body weight of all mice was monitored regularly throughout the entire process, and the mice were sacrificed at the end of the experiments on day 71.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10976516	MYXV-loaded PBMCs caused efficient lung lesion regression and longer survival.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MYXV-loaded", "PBMCs", "caused", "efficient", "lung", "lesion", "regression", "and", "longer", "...
PMC11321678	These results suggest that CNV analysis from single‐cell ATAC data is reliable for identifying the cell types and related CNV patterns for supporting subgroup annotation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11451940	Found (%): C 67.0, H 4.9, N 3.9.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Found", "(", "%", "):", "C", "67.0", ",", "H", "4.9", ",", "N", ...
PMC8658661	Cell lines have revolutionized scientific research because of their similarity to primary tissues, low cost, and ease of use and culture.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", ...
PMC10565698	I and J. qRT-PCR to validate TCF12 expression in liver cancer tissues and cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "I", "and", "J.", "qRT-PCR", "to", "validate", "TCF12", "expressi...
PMC9577200	A mixture of GO with CS has been used as an antibacterial (Kyzas et al., 2014; Ordikhani et al., 2015), wherein the CS functional groups may interact with the epoxide, carboxyl, and hydroxyl groups patterned at the base level and GO edges.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11258145	The supernatant absorbance was then measured at 570 nm using a BioTek Epoch microplate reader.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "supernatant", "absorbance", "was", "then", "measured", ...
PMC11643361	methane (tpm) ligands are neutral analogues of the commonly used anionic tris(pyrazolyl)borates and are formally derived by replacing the apical [BH]− with a C-R group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8540692	UHRF1 is involved in a macro-molecular protein complex called ‘Epigenetic Code Replication Machinery’ (ECREM), which is coordinating DNA methylation and histone modifications .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11745600

Red, Porcine C-peptide (INS); green, porcine GCG.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Red", ",", "Porcine", "C-peptide", "(", "INS", ")", ";", "green", ",", ...

PMC9429973

The control group** were matched patients treated by chemotherapy or immunechemotherapy previously in Beijing Chaoyang Hospital.

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PMC10547921

Therefore, one of the focuses of immunotherapy research and development is to develop anti-cancer therapies that can stimulate the patients’ innate immune response and promote tumor-specific T cell recruitment.

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PMC10376064

However, although water and subsequent DMF uptake were documented for both female and male (slightly reduced) mice, DMF did not improve β-amyloidosis in agreement with our previous study .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10999934

In fact, it has been well established that epithelial cells are the targets of chemotherapy in HGSOC .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "fact", ",", "it", "has", "...

PMC11792090

Upregulation of CD107a levels of NK cells following co-culture with various CAR-T cells. (

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PMC11422150

therefore suppressing the immune response of the host (Veglia et al., 2018).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "therefore", "suppressing", "the", "immune", "response", "of", ...

PMC11806106

We then calculated the IC50 for naloxone with 2.7 nM and the Ki with 1.1 nM, in line with the literature.

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PMC11514418

For the immune system, APS was identified as a multiple immune activator, which can stimulate the maturation and antigen presentation of IL-12-producing dendritic cells (DCs) and then activate T cells by interacting with anti-TLR4 on CD4+ CD25+ Treg cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11317131

Cells plated on arabinose form smaller, slower growing colonies than when plated on glucose due to the mutagenesis activity of a functional (arabinose sensitive) MP (45).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7887261

To test whether knockdown or overexpression of the candidate genes or variants induces endogenous DNA damage, we performed flow cytometric assays to measure γH2AX levels, a DNA double-strand-break marker, following siRNA knockdown and overproduction of GFP fusions of proteins of interest.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC3730428

To further prove that it is FLIP's recruitment to complex IIb that modulates sensitivity to AT-IAP/TNFα, we utilized a FLIP mutant (F114A) that cannot interact with the critical adapter protein in the complex, FADD (Figure 4c).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9164404

Abplatin could be accumulated at the tumor site via blood circulation and internalized by the cancer cells via endocytosis.

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PMC10589262

To investigate whether Golgi-retained MT-KIT primarily contributes to downstream oncogenic signaling activation, we investigated the interaction of MT-KIT with P85 and GRB2, the upstream effectors of the PI3K/AKT and MAPK/ERK pathways, respectively.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11489351

A, schematic of Notch1 signaling reporter used to quantify Notch1 activity in single cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", ",", "schematic", "of", "Notch1", "signaling", "reporte...

PMC11365983

After 5 days in culture, samples were fixed in Dent’s solution and immunofluorescently labelled with anti-Arl13b and anti-γ-tubulin antibodies (see Supplemental methods for details).

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PMC11770746

Despite the proven efficacy of platinum drugs in treating various cancers, severe side effects accompany the oncological treatments, including peripheral neuropathy.

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PMC11525028

Primers were listed in Table S8.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Primers", "were", "listed", "in", "Table", "S8", "." ] } ]

PMC9429973

Results: After the intervention, the CFS scale score of patients in the control group was lower than that in the observation group (P<0.05), and the HAMD score and HAMA score were lower than those in the observation group (P<0.05).

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PMC11721587

Upon Hh stimulation, the Hh signal transducer Smoothened (Smo) interacts with Cos2 and PKA to inhibit Ci processing (13, 16–21).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC10761218

Cell morphology revealed significant morphological changes in HepG2 and L929 cells.

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PMC11599565

The clusters of OC cells maintained in organoid conditions revealed that in the early stages, these cells develop a neuronal appearance similar to 2D models (A-E).

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PMC9424261

Cells were cultured in Dulbecco’s modified Eagle’s medium (DMEM, HyClone, Logan, UT, USA) supplemented with 1% penicillin–streptomycin and 10% fetal bovine serum (FBS, Gibco, Carlsbad, CA, USA).

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PMC7925574

A Welch two sample T-test showed significantly (*p < 0.05, **p < 0.01 and ***p < 0.001) higher E1A expression levels in 293-F compared to Freestyle 293-F and 293-H, whereas E1B was significantly higher in HEK293, 293E and 293-H cell lines compared to others.”

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9275501

Many natural active ingredients, such as berberine (BER) (Coelho et al., 2017; Wu et al., 2019b), EGCG (Cheng et al., 2016), honokiol (Huang et al., 2017; Pillai et al., 2017; Huang et al., 2020), RES (Gu et al., 2018), glycyrrhizin (GL) (Figure 1) (Lv et al., 2020), Que (Chen et al., 2019) and Sch B (Thandavarayan et ...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7802142

Using Bowtie software, the clean reads were compared with Silva database, GtRNAdb database, Rfam database and Repbase database sequence alignment to filter ribosomal RNA(rRNA), transfer RNA (tRNA), small nuclear RNA (snRNA), small nucleolar RNA (snoRNA)and other ncRNA and repeats.

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PMC11694066

P < 0.01; ns, not significant.

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PMC11705862

Informed consent for the use of brain tissue, plasma, and clinical data for research purposes were obtained from all subjects or their legal representatives in accordance with the International Declaration of Helsinki .

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PMC11371627

Overview of XK pathophysiology and clinical manifestation in our patient. (

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PMC6364197

Hematopoietic stem cell transplantation is the only way to cure leukemia.

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PMC9587298

Elderberry fruits were exhaustively extracted to obtain all extractable polyphenols, as reported by Ferreira, Silva, Silva, and Nunes (2020).

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PMC10976516

Enhanced tumor clearance compared with unarmed IVOVIR-15.Barlabé et al.Vesicular stomatitis virusRecombinant oncolytic vesicular stomatitis virus (VSV) pseudo-typed with LCMV-GP expressing tumor-associated antigens, termed VSV-GP-TAAIntravenous with KISIMA-TAA as a self-adjuvant cancer vaccine in combination with anti-...

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PMC10587429

With careful design and optimization, this model can be utilized for other pediatric and/or bone cancers.

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PMC11637276

SB203580 from Startech.

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PMC11687663

The prominent molecular interaction includes; conventional hydrogen bond, pi-pi stacked, pi-alkyl, carbon-hydrogen bond, pi-loan pair and pi-pi T shaped bond.

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PMC9429973

Twenty-eight patients from VHR group with sibling familial donor underwent allograft.

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PMC8567602

B, Schematic of the expression and recombination pattern from Myf5Cre and a mouse with anatomic distribution of Myf5Cre; Smarcb1/fl and Myf5Cre;hSS2 tumors from 16 consecutive mice in each group (two-tailed Fisher exact test for incidence of tumors in each cohort, P = 0.0002; χ = 17.03 with four degrees of freedom and ...

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PMC9429973

These stresses result in ineffective erythropoiesis and shorten RBC lifespan, leading to chronic anemia.

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PMC11633763

The protein levels of β‐catenin and HK2 were assessed by western blotting in USP22‐overexpression U2OS cells following treatment with shβ‐catenin. (

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PMC10713411

Figure 2C, 2D).

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PMC11765988

These factors are briefly analyzed.

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PMC11779993

Epidermal cells are necessary to complete wound closure.

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PMC10818573

Instead of using a dedicated instrument to maintain the isothermal amplification of reactions, other more cost-effective instruments, such as constant temperature metal baths and boiling water baths, can be used, and human-generated heat has been demonstrated for the device-free amplification of HIV .

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PMC9429973

Among dead 106 patients were of thalassemia major, 16 thalassemia intermedia and 3 sickle cell anemia.

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PMC11764090

Advances in plant multi-omics, such as genomics, transcriptomics, proteomics, microbial functional genomics, epigenetics, and metabolomics, have accelerated the discovery of the molecular mechanisms behind plant cold tolerance .

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PMC10900886

Error bars denote SEM.

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PMC11656657

In selected experiment, PBMC alone or PBMC + 143B G-CSF cells were co-cultured with increasing doses of Human G-CSF, premium grade (Miltenyi; Catalog No: 130-096-347) (ranging from 0.5 to 50 ng/ml) for 72 h. At the end of the co-cultures MDSC were analyzed by flow cytometry.

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PMC11397654

However, a tendency of these superbase compounds to decompose in solution was also observed, which could pose significant challenges to their stability and practical application.

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PMC10253553

The 786-0 cell line also expressed high levels of high phospho-NDRG1 (Thr346) and total NDRG1 (Figure 2, Figure 3 and Figure 4), which is consistent with the clinical samples (Figure 1).

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PMC9429973

of Medicine 3, University Hospital Leverkusen, Leverkusen; Dept.

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PMC10723784

There were more percentage of ovarian cancer cells in early apoptosis when treated with CBD as compared with those treated with CBG, which also correlates with the earlier results where CBD induced a stronger cytotoxicity compared to CBG.

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PMC11705862

Changes in mRNA expression levels for IRIS-1, 2 and CD59 were measured by semi-quantitative PCR performed on mRNA samples, as no specific probes with TaqMan detection system exist for IRIS-1 and 2.

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PMC11342785

Related to (Fig. S5) N here refers to the number of cells on which the FRAP was performed.

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PMC11617590

Effects of sulforaphane on the expression of apoptosis‐related proteins.

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PMC9812014

They exploit and take over the host’s cellular machinery, spreading throughout the organism .

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PMC11518994

Whole-Transcriptome RNA-SEQ was negative to fusion genes in both patients.

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PMC11574271

Consistent with this observation, increased cell migration, and invasion were observed in cells treated with the hsa-miR-659-3p inhibitor, which can also be mitigated by specific RON inhibitor BMS-777607 (Fig. S3).

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PMC11653533

Stem bark extracts of F. exasperata have shown antimicrobial effects against P. aeruginosa, S. typhi, K. pneumoniae, and S. aureus demonstrating respective inhibition zones of14.33 ± 0.33, 12.33 ± 0.33, 17.33 ± 0.67 and 15.0 ± 0.58 mm (Kingsley, 2013).

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PMC9878562

The results are in line with the in vitro observations indicating that LTB4/BLT1R signaling is required for cell-to-cell-induced migration.

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PMC6892818

mCD40L caused marked cell death by 48 h (0.8:1 ratio) in all RCC lines, comparable to EJ (Fig. 2b), with similar observations at 72 h (Supplementary Fig. 1).

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PMC11637284

The latter has two TMDs and its N- and C-termini face the cytosol .

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PMC11424574

Colony formation efficiency (%) = (numbers of shMTA2 cell colonies/ number of shLuc cell colonies) × 100%.

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PMC9429973

The IL-35 receptors gp130 and IL-12Rβ were found to be expressed on human MKs, suggesting a role for IL-35 during megakaryopoiesis.

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PMC11190062

Genes with logFC > 0 or logFC < 0 and −log10 (adj.

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PMC11746948

The protein concentration in the supernatant was determined using the BCA Protein Assay Kit (Thermo Fisher Scientific, USA).

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PMC11770130

Notably, a similar increase in food intake was also observed in Ntsr2 AKO mice kept in the thermoneutral condition (Supplementary information, Fig. S3d).

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PMC6835762

In particular, while C18 chains promote favorable interactions with DXMP, having too many C18 chains decreases solubility, preventing the polymer from interacting with surrounding DXMP molecules.

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PMC11319300

The human MYEOV-3′-putative enhancer was defined by active regions determined by ATAC-STAR-seq in GM12878, together with the presence of histone marks H3K27ac, H3K4me1 (with or without the presence of H3K4me3) and regions of DNase I hypersensitivity defined by DNase-seq.

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PMC11574029

M Transwell assay evaluating the invasion and migration abilities of T24 and 5637 cells after NOTCH3 knockdown.

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PMC11637284

The region mostly affected is indicated by broken lines in Fig 3B.

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PMC8633974

The funding authorities of this study did not participate in any part of the experimental design, execution, or data analysis.

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PMC11337594

We speculate that this is related to the period of Ki67 expression.

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PMC11334037

IGF2 was screened and analyzed using Gene Expression Omnibus (GEO: GSE225819) data.

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PMC11725127

LC–MS/MS analysis.

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PMC11799978

Cells were lysed on ice for 30 min with intermittent vertexing.

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PMC10994876

Correspondingly, the loss of PTEN due to the YAP overexpression led to an increase in mTOR expression, while the transcription level of S6K did not show any significant changes.

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PMC9352806

Protein concentrations were determined by BCA assay kit (Nanjing Jiancheng Bioengineering Institute, Nanjing, China).

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PMC10196713

no. A11034; Invitrogen; Thermo Fisher Scientific, Inc.) for 30 min at room temperature.

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PMC11791203

Two-dimensional docking interaction images of 1,2-benzenedicarboxylic acid, Cyclododecanol, 2,4-Ditert-Butylphenol and Sulfurous acid, hexyl octyl ester onto Caspase 9 and (C) RC plot of 1,2-benzenedicarboxylic acid, Cyclododecanol, 2,4-Ditert-Butylphenol and Sulfurous acid, hexyl octyl ester onto Caspase 9.

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PMC9436459

Morusalbanol A (148) from M. alba, possessing the same 6-membered oxygen ring as 18 − 22, has cis–trans configuration.

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PMC11301242

Chromothripsis events were identified using ShatterSeek with SV and CN data (Supplementary Fig. 4A).

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PMC11699465

The concurrent work of our lab is to illustrate the role of TMEM199 in influencing PPI immunotherapy and then seek a replacement drug for the patients who accept immunotherapy and chemotherapy.

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PMC10380508

Furthermore, the PAXclusterA subtype was observed significantly more frequently in early-stage tumors: stage I and stage II (p < 0.001), grade 1 and grade 2 (p = 0.023), and T stage 1 (T1) and T stage 2 (T2) (p < 0.001).

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PMC11216402

By aggregating motif activity scores following pairwise comparisons between each Mes-like cell line and each ENCODE fibroblast, we rediscovered AP-1 and RUNX to be active in Mes-like GC as opposed to TWIST and ZEB being more active in normal fibroblasts (Fig. 7E).

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PMC11359735

Left panel: the immunoprecipitate was analyzed by SDS-PAGE followed by fluorography.

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PMC9429973

BAT patients were most frequently treated with tyrosine kinase inhibitors (73 out of 121 LOTs, 60%) or cytoreductive therapies (46 out of 121 LOTs, 38%).

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PMC9532503

The crosslinking of mAb and FcγR will stimulate ADCC which is based on the binding affinities of this interaction.

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PMC9684669

As revealed by these results, they indicated the CAMK2/CREB1 pathway was overactive in the A2780-ADR cells.

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PMC10452486

Interestingly, the trophoblasts do not express HLA-A and HLA-B but only HLA-C, HLA-E, HLA-G , and HLA-F .

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PMC9429973

In 5 pts, impeding relapse was predicted by a CH-associated mut MRD conversion with a median VAF of 0.27 (range 0.06-1.0)% at a median of 103 (range 14-199) days prior to relapse.

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PMC11746948

The body weight of all mice was monitored regularly throughout the entire process, and the mice were sacrificed at the end of the experiments on day 71.

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PMC10976516

MYXV-loaded PBMCs caused efficient lung lesion regression and longer survival.

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PMC11321678

These results suggest that CNV analysis from single‐cell ATAC data is reliable for identifying the cell types and related CNV patterns for supporting subgroup annotation.

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PMC11451940

Found (%): C 67.0, H 4.9, N 3.9.

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PMC8658661

Cell lines have revolutionized scientific research because of their similarity to primary tissues, low cost, and ease of use and culture.

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PMC10565698

I and J. qRT-PCR to validate TCF12 expression in liver cancer tissues and cells.

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PMC9577200

A mixture of GO with CS has been used as an antibacterial (Kyzas et al., 2014; Ordikhani et al., 2015), wherein the CS functional groups may interact with the epoxide, carboxyl, and hydroxyl groups patterned at the base level and GO edges.

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PMC11258145

The supernatant absorbance was then measured at 570 nm using a BioTek Epoch microplate reader.

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PMC11643361

methane (tpm) ligands are neutral analogues of the commonly used anionic tris(pyrazolyl)borates and are formally derived by replacing the apical [BH]− with a C-R group.

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PMC8540692

UHRF1 is involved in a macro-molecular protein complex called ‘Epigenetic Code Replication Machinery’ (ECREM), which is coordinating DNA methylation and histone modifications .

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