OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11546117	At the end of the experiment (2 h), samples were taken from the receptor and donor compartments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "the", "end", "of...
PMC11802929	b Cell abundancy changes from post-acute to acute timepoint for each PG-TCR grouping.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "b", "Cell", "abundancy", "changes", "from", "post-acute", "to", "acute", ...
PMC11295144	Scatter-plot showing individual IPSC frequencies in each group. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scatter-plot", "showing", "individual", "IPSC", "frequencies", "in", "each", "group", ".", "(" ] } ]
PMC11560255	After washing, the Star Trek Universal HRP Detection System was added, and Mayer’s hematoxylin was used for counterstaining.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "washing", ...
PMC11732523	The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC6799808	Interestingly, ectopic expression of dominant-negative AMPKα (AMPKα-dn) by infection with Ad-AMPKα-dn partially prevented GLPT from inhibiting mTORC1-mediated S6K1 and 4E-BP1 phosphorylation (Fig. 5d), indicating that GLPT indeed inhibits mTORC1 partly through activation of AMPK.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9927933	Moreover, Ube2c deletion in mouse embryonic fibroblasts (MEFs) also suppressed cell growth (Figure 1E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "Ube2c", "deletio...
PMC11748363	Five other compounds (2, 12, 18, 32, and 33) had lower but still promising activity on Mtb H37Ra (MIC = 15.625 μg/mL).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: To study if there is erythrocytosis in PHD2 patients people living at sea altitude like our patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "To", "study", ...
PMC11721064	Additionally, double immunofluorescence staining of vimentin (Vim) with CK12, ΔNp63α, or PAX6 was performed to confirm the purity of isolated LNCs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9250505	Inhibition of BADS99 phosphorylation partially overcame acquired cisplatin resistance through the promotion of apoptosis and inhibition of CSC-like behavior.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Inhibition", "of", "BADS99", "pho...
PMC10198699	In this article, ownership of the cell lines is investigated from a South African legal perspective by considering three possible contemporary scenarios bearing points of similarity to the Henrietta Lacks case.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11075223	There are only 27 carbons in the parent nucleus of foetidonol-type and C-16 is connected with C-24 to form a six-membered carbon ring .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There",...
PMC11185260	Importantly, there was a significant difference in survival when scL-SMARCB1 was administered in combination with cisplatin compared with cisplatin alone (Figure 6F).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11798926	It is possible that removal of 20 amino acids in the deletion mutant could disrupt an interaction with GluA2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "possible", "that", ...
PMC11774112	The samples were prepared by placing one drop of a dilute dispersion onto a copper grid coated with a carbon membrane.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "samples", ...
PMC11224020	CCR7–GFP mice were obtained from Jackson Laboratory (027913) and were bred in our animal facility.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CCR7–GFP", "mice", "were", "obtained", "from", ...
PMC8922418	To improve the practice in future applications, we should: (1) design more specific gRNA and Cas9 mutants to reduce the off-target effects; (2) develop single- or multi-functional base editors that can directly and accurately edit bases without DSB-induced NHEJ or HDR; (3) design Cas9 variants with flexible PAM sequenc...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9872547	The weight-weight ratio of 1: 25 was obtained as a suitable and stable ratio (without curcumin precipitation from the nano-carrier).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC9847912	Furthermore, after 40-h of incubation, the MAGIC-5A plates were inspected via light microscopy to ensure that the level of virus-induced syncytia in the no-drug wells was ≤25% of the total cells in monolayer; plates with >25% syncytia were discarded and were not analyzed further.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11803210	The overlapping area denotes the number of co-expressed genes between the two conditions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "overlapping", "area", "denotes", "the", "number", "of", "co-expresse...
PMC11795610	This trend, however, was reversed in the HC-067047+myricetin group (Figure S4), suggesting that myricetin induced cell cycle arrest and growth arrest depending on the TRPV4 activation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11283030	The two ccRCC cell lines expressing high level of ACLY, 786-O and A498, were used in the following experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC11730305	In agreement with this work, the induction of oxidative stress following exposure to metal-based nanoparticles has been reported in the literature.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "agreem...
PMC11612626	Cells were imaged using an inverted fluorescence microscope for GFP expression, and luciferase activity was assessed using a luciferase assay kit (Promega) and luminometer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11640247	This variant affects the Switch II region of RAC3 and causes a peculiar and particularly severe “fetopathy” which differs from typical NEDBAF phenotypes, raising the possibility that specific molecular disruptions may be involved in its pathogenesis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11713609	PHLDA2 is critical for p53-mediated ferroptosis. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PHLDA2", "is", "critical", "for", "p53-mediated", "ferroptosis", ".", "(" ] } ]
PMC9429973	However, neutropenic fever and grade 3-4 thrombocytopenia differed statistically significantly (χ test, p<0.05) between R-DA-EPOCH-21 and R-mNHL-BFM-90 arms.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11388384	The total number of molecules in the receiver cell field was recorded at each time step.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "total", "number", "of", "molecules", "in", ...
PMC10748106	Next, the alignment of the three best designed iridoids (D9, D10, D35, D36, D55, D56, D58, D60, D61, and D62) and the most structurally similar active iridoid (Artselaenin A) is shown in Figure 16.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11758416	Confirm under a microscope that cells are completely detached before proceeding.f.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Confirm", "under", "a", "microscope", "that", "cells", "are", "completely", "detached", ...
PMC11487720	Alternatively, α-tubulin relocates to the bubble through enlarged nuclear pores.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Alternatively", ",", "α-tubulin", "relocates", "to", "the", "bubble", "through", "enlarged"...
PMC9429973	Patients had a mean of 5.1 VOCs, 4.7 ER visits and 3.6 all-cause hospitalizations per year during the 2-year baseline period.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "...
PMC7709199	Thus, it appears that the immature glycan is needed for the proper functioning of IL-12B, probably to ensure proper folding and stability.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC2614415	Each time point represents data from at least 3 independent experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", "time", "point", "represents", "data", "from", "at", "least", "3", "independen...
PMC11770746	Saline (150 μL), cisplatin (3 mg/kg), cisplatin + paclitaxel (3 + 8.5 mg/kg), and cisPt(Taxol)(OH) (12 mg/kg) were injected into female BALB/c OlaHsd mice (six mice per group)–8 weeks of age at days 1, 3, and 5.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11301242	Additionally, it is noteworthy that co-amplification of protein-coding and non-coding genes is observed on the circular amplicons (Fig. 2E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ...
PMC4360730	However, searching the term ‘breast’ returns data for experiments using both H. sapiens breast tissue and M. musculus mammary tissue because the term ‘mammary tissue’ has the synonym of ‘lobe of breast’ (Figure 3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11518702	Singular Y128F or Y148F mutations, however, do not interrupt HGAL-SYK co-immunoprecipitation (13).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Singular", "Y128F", "or", "Y148F", "mutations", ",", ...
PMC11464982	The full opinion will be published in accordance with Article 12 of Regulation (EC) No 1331/2008 once the decision on confidentiality will be received from the European Commission.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4360730	Inferred relationships are connections between two terms that are transitively reasoned via the explicit relationships.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Inferred", "relationships", "are", "connections", "between", "two...
PMC11754432	The following day cells were incubated with 1:500 secondary antibody for 45 min and counterstained with 20 nM MEMGlow 488 (Cytoskeleton) for 10 min and 1 µg/ml DAPI for 1 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11666785	Correlation (χ = 0.7) was carried out for 2, 3, and 4 frames that span an exposure time of 60, 90, 120ms.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6222635	Then, the pH value of the solution was adjusted to 7 with NaOH.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", "the", "pH", "value", "of", "the", "solution", ...
PMC9429973	Results: The monocarboxylate transporters (MCT-1 and -4), orchestrating lactate intake, were significatively upregulated in CD34 cells and sera derived from MF-patients compared to healthy donor.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9268620	The cells were then dehydrated in a series of 35% to 50% to 75% to 95% of acetone for 5 min each and, finally, with 3 changes of 100% acetone for 10 min each.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10197932	Probably, Mcl-1L, under ultrasound stress, undergoes degradation or phosphorylation/ubiquitylation followed by proteasome degradation in healthy resting lymphocytes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Probably", ",", "Mcl-1L", ...
PMC11453018	Quercetin showed no effectiveness even at the highest tested concentrations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Quercetin", "showed", "no", "effectiveness", "even", "at", "the", "highest", "tested", "concentr...
PMC11401350	The main problem of in vivo gene delivery is the possibility of generating off-target cell lentiviral vector (LV) transduction causing severe health risks and adverse effects .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10362265	The C74, which is one of the cysteines reported to form a novel intermolecular disulfide bridge in the human complex, is also located in this helix .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11730320	In the absence of pTCRα, TCRβ chains appear reliant on expression of prematurely rearranged TCRα chains, which occurs in only a small percentage of cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9874064	These drugs can cause DNA damage and induce cell apoptosis by cross-linking with DNAs in cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "drugs", "can", "cause", "DNA", "da...
PMC10988555	This study was performed at 9, 18, and 24 h after the exposure to the IC50 concentrations of the complexes 2–4 (Figure 14).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11611077	In group 1, prestin was expressed in the cell membrane and functioned well.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "group", "1", ",", "prestin", "was", "expressed", "in", ...
PMC11792090	All experiments were performed independently at least three times.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "experiments", "were", "performed", "independently", "at", "least", "three", "times", "." ] } ]
PMC9429973	In its most severe form, β-thalassemia is caused by mutations in both alleles of the β-globin gene.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "its", "most", "severe", "form", ...
PMC9429973	Compelling evidence are suggesting that persistent antigen stimulation in the tumor microenvironment can differentiate T effector cells into terminally exhausted T cells, a functional state characterized by decrease in proliferation, cytotoxicity, and cytokine production.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11543935	Values are generated with an AlamarBlue assay with 20 hours of incubation time.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Values", "are", "generated", "with", "an", "AlamarBlue", "assay", "with", ...
PMC7185206	While genetic loss of these proteases is lethal in mice and causes severe inflammatory disease in humans, clinical inhibitors of ADAM10 and ADAM17 have been studied and found to be safe in other indications.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10988555	Evaluation of the fibroblasts’ remission after 24 h of exposure to the IC50 of the complexes 2–4 by inverted microscopy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Evaluation", "of", ...
PMC11766332	Among these, several glycosylation pathways were identified as being associated with one or more miRNAs (Figure 2): N-glycan biosynthesis (N = 2 miRNAs); glycosaminoglycan (GAG) biosynthesis–keratan sulfate (N = 3 miRNAs); mucin-type O-glycan biosynthesis (N = 3 miRNAs); glycosaminoglycan biosynthesis–chondroitin sulfa...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9577200	Then, we examined the concentrations of the most efficient substance that showed high results as an antibacterial agent for its ability to have anticancer activity on the HeLa cell line to reach the lowest anticancer concentration with fewer side effects.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11803149	n = 6 (young cells), n = 4 (aged cells).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "n", "=", "6", "(", "young", "cells", ")", ",", ...
PMC11564405	A IHC images of RILPL2 expression and CD4 + T cell infiltration.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "IHC", "images", "of", "RILPL2", "expression", "and", "CD4", "+", "T",...
PMC6133382	Our data suggest that this cell line possesses several essential characteristics required for current Good Manufacturing Practices (cGMPs), such as robust growth in well-defined serum-free medium, the ability to grow to high cell densities in suspension culture, a well-defined mutation of the MGAT1 gene, and freedom fr...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11766332	ASD symptoms may occur in CDGs and may also represent hallmark features in CDG patients presenting with psychiatric symptoms .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ASD", "symptoms", "may", "occur",...
PMC11761919	3Characteristics of encapsulated E. faecalis in simulated gastricintestinal fluid. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "3Characteristics", "of", "encapsulated", "E.", "faecalis", "in", "simulated", "gastricintestinal", "fl...
PMC8041314	A pheophorbide A solution (20 μL; 5 μM) was supplemented, and the reaction mixture was incubated for 120 min (5% CO2-humidified atmosphere; 37 °C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11040965	B Photomicrographs of bone marrow biopsies from MGUS and MM patients stained for miR29b (pink) and DNMT3B (brown).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "B", "Photomi...
PMC11173119	The morphology of macrophage-like cells derived from control iPSCs significantly differed from that of cells derived from iPSCs with a mutation in the MEFV gene.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10123657	This approach could easily be used in vivo in leukemia xenograft models.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "approach", "could", "easily", "be", "used", "in", "vivo", "in", "l...
PMC11740907	Furthermore, cancer cells have a higher degree of uptake efficiency for nanoparticles in comparison to unbound medicines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "cancer", "cells", ...
PMC11518702	In Isoform C, HGAL’s palmitoylation site is deleted, with Arg 10 represented (rather than S10).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "Isoform", "C", "...
PMC11366496	Data S1 lists the specific procedure.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "S1", "lists", "the", "specific", "procedure", "." ] } ]
PMC10944868	The boiled egg model is a simple and inexpensive method that has been used to predict the ADME parameters of drugs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "boiled", "...
PMC11395280	We have identified a novel role for T-ALL therapy that may provide a platform for the development of pharmaceuticals in the future.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "have",...
PMC11711871	C The values of the area under the curve (AUCs), maximum effects (Emax), and the half-maximal effective concentrations (EC50) upon A KCl and B Phe stimulation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8481254	However, the contributions of YAP overexpression or knockdown to the expression of CDK19 were not significant (Supplementary Fig. 5G).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However...
PMC8759873	There is a significant difference in cell proliferation ability between the pcDNA3.1-VHL group and the untreated group and the transfected pcDNA3.1(+) group (PV0.05).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC8973725	The construction of TMA was performed as previously described.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "construction", "of", "TMA", "was", "performed", "as", "previously", "described", "." ] } ]
PMC2614415	One mechanism that might contribute to this phenomenon is that Aurora-A renders cells resistant to paclitaxel-induced apoptosis and stimulates Akt1 and Akt2 activity in wild-type p53 but not p53-null ovarian cancer cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7553912	From these findings, OSM is suggested to have no association with the recruitment and phenotypic changes of renal macrophages in the process of kidney stone formation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9250505	Results represent the mean ± SEM of six animals.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", "represent", "the", "mean", "±", "SEM", "of", "six", "animals", "." ] } ]
PMC11770746	The results of the in vivo efficacy study indicated that, to achieve effective inhibition of tumor growth in the CT26 murine colon cancer model, it was necessary to treat the mice with both platinum and paclitaxel.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", ...
PMC9429973	Twenty nine (58%) pts had BCR::ABL1 mutations, 20 pts (40%) had BCR::ABL1, 8 (16%) pts had at least two mutations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8557138	Vlachogiannis et al., used PDO models to establish a living biobank of 71 patients with gastrointestinal cancers providing valuable insights into histopathological markers of colorectal cancer including CDX-2 and CK7.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11538390	Primary Epidermal Keratinocytes: Normal, Human, Neonatal Foreskin (HEKn) purchased from American Type Culture Collection (ATCC PCS-200-010) were maintained and cultured as per manufacturer’s instruction in dermal cell basal medium (ATCC PCS-200-030) supplemented with keratinocyte growth kit (ATCC PCS-200-040).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Response rates were consistent across both RP2Ds supporting their equivalence (Table).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Response", "rates", "were", "consistent", "across", "both", "RP2Ds", "suppo...
PMC11291490	Data was analyzed using CytExpert software.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "was", "analyzed", "using", "CytExpert", "software", "." ] } ]
PMC11794847	To elucidate the potential interactions between Jurkat T cells and lung cancer cells in vivo, we employed a murine tumor xenograft model.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC7342409	After 48 hours, the apoptosis rates of the GIST882 group, the GIST882-ir group, the GIST882-ir+ im group, the GIST882-ir + CQ group, the GIST882-ir +im+ CQ group were 6.4%, 4.3%, 8.6%, 9.2% and 19.3%, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O"...
PMC10958426	Based on the 20 PCs, we clustered the cells using FindNeighbors and FindClusters with default parameter.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Based", "on", "the", "20", "PCs", ",", ...
PMC11752767	Table 3Comparison among ACT modalitiesTILTCR-TCAR-TCAR-NKTumor killing cellsT lymphocytesT lymphocytes with transducted tumor-specific receptorT lymphocytes with the chimeric antigen receptorNK cells with chimeric antigen receptorsSourcesAutologous tumor infiltrating zoneLymphapheresis of autologous peripheral blood ce...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11604830	LPS was injected into the right striatum of five mice to induce inflammation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "LPS", "was", "injected", "into", "the", "right", "striatum", "of", "f...
PMC11513011	In KK-47, DIB decreased the expression of N-cadherin at 50 nM and 100 nM and increased the expression of E-cadherin at 100 nM. In T24, DIB increased the expression of E-cadherin at 50 nM and 100 nM. In 5637, DIB decreased the expression of N-cadherin and Vimentin at 50 nM and 100 nM (Fig. 4A).	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLin...
PMC11795610	Keratin 14 mRNA. (	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Keratin", "14", "mRNA", ".", "(" ] } ]
PMC6190245	The cells were grown as monolayers in a 25-cm flask.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cells", "were", "grown", "as", "monolayers", "in", "a", "25-cm", "flask", "." ]...
PMC11683130	So we hypothesize that increased SerpinB3/B13 expression suppress TGM3 activation by inhibiting cathepsin L activity, thereby affecting cross-linking of the stratum corneum and resulting in impaired skin barrier.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11489351	Additionally, our results support prior work showing that LDHA activity increases with increased pHi (62) and suggests that changes in LDHA transcription, expression, and activity could synergize to support cellular metabolism changes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11637276	Bafilomcyin A1, FR180204, PD98059, SB202190, and SB203580 from MedChem express.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Bafilomcyin", "A1", ",", "FR180204", ",", "PD98059", ",", "SB202...

PMC11546117

At the end of the experiment (2 h), samples were taken from the receptor and donor compartments.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "the", "end", "of...

PMC11802929

b Cell abundancy changes from post-acute to acute timepoint for each PG-TCR grouping.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "b", "Cell", "abundancy", "changes", "from", "post-acute", "to", "acute", ...

PMC11295144

Scatter-plot showing individual IPSC frequencies in each group. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scatter-plot", "showing", "individual", "IPSC", "frequencies", "in", "each", "group", ".", "(" ] } ]

PMC11560255

After washing, the Star Trek Universal HRP Detection System was added, and Mayer’s hematoxylin was used for counterstaining.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "washing", ...

PMC11732523

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC6799808

Interestingly, ectopic expression of dominant-negative AMPKα (AMPKα-dn) by infection with Ad-AMPKα-dn partially prevented GLPT from inhibiting mTORC1-mediated S6K1 and 4E-BP1 phosphorylation (Fig. 5d), indicating that GLPT indeed inhibits mTORC1 partly through activation of AMPK.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9927933

Moreover, Ube2c deletion in mouse embryonic fibroblasts (MEFs) also suppressed cell growth (Figure 1E).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "Ube2c", "deletio...

PMC11748363

Five other compounds (2, 12, 18, 32, and 33) had lower but still promising activity on Mtb H37Ra (MIC = 15.625 μg/mL).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Aims: To study if there is erythrocytosis in PHD2 patients people living at sea altitude like our patients.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "To", "study", ...

PMC11721064

Additionally, double immunofluorescence staining of vimentin (Vim) with CK12, ΔNp63α, or PAX6 was performed to confirm the purity of isolated LNCs.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC9250505

Inhibition of BADS99 phosphorylation partially overcame acquired cisplatin resistance through the promotion of apoptosis and inhibition of CSC-like behavior.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Inhibition", "of", "BADS99", "pho...

PMC10198699

In this article, ownership of the cell lines is investigated from a South African legal perspective by considering three possible contemporary scenarios bearing points of similarity to the Henrietta Lacks case.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11075223

There are only 27 carbons in the parent nucleus of foetidonol-type and C-16 is connected with C-24 to form a six-membered carbon ring .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There",...

PMC11185260

Importantly, there was a significant difference in survival when scL-SMARCB1 was administered in combination with cisplatin compared with cisplatin alone (Figure 6F).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC11798926

It is possible that removal of 20 amino acids in the deletion mutant could disrupt an interaction with GluA2.

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PMC11774112

The samples were prepared by placing one drop of a dilute dispersion onto a copper grid coated with a carbon membrane.

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PMC11224020

CCR7–GFP mice were obtained from Jackson Laboratory (027913) and were bred in our animal facility.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CCR7–GFP", "mice", "were", "obtained", "from", ...

PMC8922418

To improve the practice in future applications, we should: (1) design more specific gRNA and Cas9 mutants to reduce the off-target effects; (2) develop single- or multi-functional base editors that can directly and accurately edit bases without DSB-induced NHEJ or HDR; (3) design Cas9 variants with flexible PAM sequenc...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9872547

The weight-weight ratio of 1: 25 was obtained as a suitable and stable ratio (without curcumin precipitation from the nano-carrier).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...

PMC9847912

Furthermore, after 40-h of incubation, the MAGIC-5A plates were inspected via light microscopy to ensure that the level of virus-induced syncytia in the no-drug wells was ≤25% of the total cells in monolayer; plates with >25% syncytia were discarded and were not analyzed further.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11803210

The overlapping area denotes the number of co-expressed genes between the two conditions.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "overlapping", "area", "denotes", "the", "number", "of", "co-expresse...

PMC11795610

This trend, however, was reversed in the HC-067047+myricetin group (Figure S4), suggesting that myricetin induced cell cycle arrest and growth arrest depending on the TRPV4 activation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11283030

The two ccRCC cell lines expressing high level of ACLY, 786-O and A498, were used in the following experiments.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...

PMC11730305

In agreement with this work, the induction of oxidative stress following exposure to metal-based nanoparticles has been reported in the literature.

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PMC11612626

Cells were imaged using an inverted fluorescence microscope for GFP expression, and luciferase activity was assessed using a luciferase assay kit (Promega) and luminometer.

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PMC11640247

This variant affects the Switch II region of RAC3 and causes a peculiar and particularly severe “fetopathy” which differs from typical NEDBAF phenotypes, raising the possibility that specific molecular disruptions may be involved in its pathogenesis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11713609

PHLDA2 is critical for p53-mediated ferroptosis. (

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PMC9429973

However, neutropenic fever and grade 3-4 thrombocytopenia differed statistically significantly (χ test, p<0.05) between R-DA-EPOCH-21 and R-mNHL-BFM-90 arms.

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PMC11388384

The total number of molecules in the receiver cell field was recorded at each time step.

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PMC10748106

Next, the alignment of the three best designed iridoids (D9, D10, D35, D36, D55, D56, D58, D60, D61, and D62) and the most structurally similar active iridoid (Artselaenin A) is shown in Figure 16.

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PMC11758416

Confirm under a microscope that cells are completely detached before proceeding.f.

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PMC11487720

Alternatively, α-tubulin relocates to the bubble through enlarged nuclear pores.

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PMC9429973

Patients had a mean of 5.1 VOCs, 4.7 ER visits and 3.6 all-cause hospitalizations per year during the 2-year baseline period.

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PMC7709199

Thus, it appears that the immature glycan is needed for the proper functioning of IL-12B, probably to ensure proper folding and stability.

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PMC2614415

Each time point represents data from at least 3 independent experiments.

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PMC11770746

Saline (150 μL), cisplatin (3 mg/kg), cisplatin + paclitaxel (3 + 8.5 mg/kg), and cisPt(Taxol)(OH) (12 mg/kg) were injected into female BALB/c OlaHsd mice (six mice per group)–8 weeks of age at days 1, 3, and 5.

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PMC11301242

Additionally, it is noteworthy that co-amplification of protein-coding and non-coding genes is observed on the circular amplicons (Fig. 2E).

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PMC4360730

However, searching the term ‘breast’ returns data for experiments using both H. sapiens breast tissue and M. musculus mammary tissue because the term ‘mammary tissue’ has the synonym of ‘lobe of breast’ (Figure 3).

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PMC11518702

Singular Y128F or Y148F mutations, however, do not interrupt HGAL-SYK co-immunoprecipitation (13).

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PMC11464982

The full opinion will be published in accordance with Article 12 of Regulation (EC) No 1331/2008 once the decision on confidentiality will be received from the European Commission.

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PMC4360730

Inferred relationships are connections between two terms that are transitively reasoned via the explicit relationships.

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PMC11754432

The following day cells were incubated with 1:500 secondary antibody for 45 min and counterstained with 20 nM MEMGlow 488 (Cytoskeleton) for 10 min and 1 µg/ml DAPI for 1 min.

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PMC11666785

Correlation (χ = 0.7) was carried out for 2, 3, and 4 frames that span an exposure time of 60, 90, 120ms.

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PMC6222635

Then, the pH value of the solution was adjusted to 7 with NaOH.

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PMC9429973

Results: The monocarboxylate transporters (MCT-1 and -4), orchestrating lactate intake, were significatively upregulated in CD34 cells and sera derived from MF-patients compared to healthy donor.

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PMC9268620

The cells were then dehydrated in a series of 35% to 50% to 75% to 95% of acetone for 5 min each and, finally, with 3 changes of 100% acetone for 10 min each.

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PMC10197932

Probably, Mcl-1L, under ultrasound stress, undergoes degradation or phosphorylation/ubiquitylation followed by proteasome degradation in healthy resting lymphocytes.

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PMC11453018

Quercetin showed no effectiveness even at the highest tested concentrations.

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PMC11401350

The main problem of in vivo gene delivery is the possibility of generating off-target cell lentiviral vector (LV) transduction causing severe health risks and adverse effects .

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PMC10362265

The C74, which is one of the cysteines reported to form a novel intermolecular disulfide bridge in the human complex, is also located in this helix .

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PMC11730320

In the absence of pTCRα, TCRβ chains appear reliant on expression of prematurely rearranged TCRα chains, which occurs in only a small percentage of cells.

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PMC9874064

These drugs can cause DNA damage and induce cell apoptosis by cross-linking with DNAs in cancer cells.

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PMC10988555

This study was performed at 9, 18, and 24 h after the exposure to the IC50 concentrations of the complexes 2–4 (Figure 14).

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PMC11611077

In group 1, prestin was expressed in the cell membrane and functioned well.

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PMC11792090

All experiments were performed independently at least three times.

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PMC9429973

In its most severe form, β-thalassemia is caused by mutations in both alleles of the β-globin gene.

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PMC9429973

Compelling evidence are suggesting that persistent antigen stimulation in the tumor microenvironment can differentiate T effector cells into terminally exhausted T cells, a functional state characterized by decrease in proliferation, cytotoxicity, and cytokine production.

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PMC11543935

Values are generated with an AlamarBlue assay with 20 hours of incubation time.

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PMC7185206

While genetic loss of these proteases is lethal in mice and causes severe inflammatory disease in humans, clinical inhibitors of ADAM10 and ADAM17 have been studied and found to be safe in other indications.

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PMC10988555

Evaluation of the fibroblasts’ remission after 24 h of exposure to the IC50 of the complexes 2–4 by inverted microscopy.

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PMC11766332

Among these, several glycosylation pathways were identified as being associated with one or more miRNAs (Figure 2): N-glycan biosynthesis (N = 2 miRNAs); glycosaminoglycan (GAG) biosynthesis–keratan sulfate (N = 3 miRNAs); mucin-type O-glycan biosynthesis (N = 3 miRNAs); glycosaminoglycan biosynthesis–chondroitin sulfa...

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PMC9577200

Then, we examined the concentrations of the most efficient substance that showed high results as an antibacterial agent for its ability to have anticancer activity on the HeLa cell line to reach the lowest anticancer concentration with fewer side effects.

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PMC11803149

n = 6 (young cells), n = 4 (aged cells).

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PMC11564405

A IHC images of RILPL2 expression and CD4 + T cell infiltration.

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PMC6133382

Our data suggest that this cell line possesses several essential characteristics required for current Good Manufacturing Practices (cGMPs), such as robust growth in well-defined serum-free medium, the ability to grow to high cell densities in suspension culture, a well-defined mutation of the MGAT1 gene, and freedom fr...

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PMC11766332

ASD symptoms may occur in CDGs and may also represent hallmark features in CDG patients presenting with psychiatric symptoms .

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PMC11761919

3Characteristics of encapsulated E. faecalis in simulated gastricintestinal fluid. (

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PMC8041314

A pheophorbide A solution (20 μL; 5 μM) was supplemented, and the reaction mixture was incubated for 120 min (5% CO2-humidified atmosphere; 37 °C).

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PMC11040965

B Photomicrographs of bone marrow biopsies from MGUS and MM patients stained for miR29b (pink) and DNMT3B (brown).

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PMC11173119

The morphology of macrophage-like cells derived from control iPSCs significantly differed from that of cells derived from iPSCs with a mutation in the MEFV gene.

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PMC10123657

This approach could easily be used in vivo in leukemia xenograft models.

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PMC11740907

Furthermore, cancer cells have a higher degree of uptake efficiency for nanoparticles in comparison to unbound medicines.

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PMC11518702

In Isoform C, HGAL’s palmitoylation site is deleted, with Arg 10 represented (rather than S10).

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PMC11366496

Data S1 lists the specific procedure.

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PMC10944868

The boiled egg model is a simple and inexpensive method that has been used to predict the ADME parameters of drugs.

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PMC11395280

We have identified a novel role for T-ALL therapy that may provide a platform for the development of pharmaceuticals in the future.

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PMC11711871

C The values of the area under the curve (AUCs), maximum effects (Emax), and the half-maximal effective concentrations (EC50) upon A KCl and B Phe stimulation.

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PMC8481254

However, the contributions of YAP overexpression or knockdown to the expression of CDK19 were not significant (Supplementary Fig. 5G).

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PMC8759873

There is a significant difference in cell proliferation ability between the pcDNA3.1-VHL group and the untreated group and the transfected pcDNA3.1(+) group (PV0.05).

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PMC8973725

The construction of TMA was performed as previously described.

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PMC2614415

One mechanism that might contribute to this phenomenon is that Aurora-A renders cells resistant to paclitaxel-induced apoptosis and stimulates Akt1 and Akt2 activity in wild-type p53 but not p53-null ovarian cancer cells .

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PMC7553912

From these findings, OSM is suggested to have no association with the recruitment and phenotypic changes of renal macrophages in the process of kidney stone formation.

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PMC9250505

Results represent the mean ± SEM of six animals.

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PMC11770746

The results of the in vivo efficacy study indicated that, to achieve effective inhibition of tumor growth in the CT26 murine colon cancer model, it was necessary to treat the mice with both platinum and paclitaxel.

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PMC9429973

Twenty nine (58%) pts had BCR::ABL1 mutations, 20 pts (40%) had BCR::ABL1, 8 (16%) pts had at least two mutations.

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PMC8557138

Vlachogiannis et al., used PDO models to establish a living biobank of 71 patients with gastrointestinal cancers providing valuable insights into histopathological markers of colorectal cancer including CDX-2 and CK7.

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PMC11538390

Primary Epidermal Keratinocytes: Normal, Human, Neonatal Foreskin (HEKn) purchased from American Type Culture Collection (ATCC PCS-200-010) were maintained and cultured as per manufacturer’s instruction in dermal cell basal medium (ATCC PCS-200-030) supplemented with keratinocyte growth kit (ATCC PCS-200-040).

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PMC9429973

Response rates were consistent across both RP2Ds supporting their equivalence (Table).

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PMC11291490

Data was analyzed using CytExpert software.

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PMC11794847

To elucidate the potential interactions between Jurkat T cells and lung cancer cells in vivo, we employed a murine tumor xenograft model.

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PMC7342409

After 48 hours, the apoptosis rates of the GIST882 group, the GIST882-ir group, the GIST882-ir+ im group, the GIST882-ir + CQ group, the GIST882-ir +im+ CQ group were 6.4%, 4.3%, 8.6%, 9.2% and 19.3%, respectively.

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PMC10958426

Based on the 20 PCs, we clustered the cells using FindNeighbors and FindClusters with default parameter.

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PMC11752767

Table 3Comparison among ACT modalitiesTILTCR-TCAR-TCAR-NKTumor killing cellsT lymphocytesT lymphocytes with transducted tumor-specific receptorT lymphocytes with the chimeric antigen receptorNK cells with chimeric antigen receptorsSourcesAutologous tumor infiltrating zoneLymphapheresis of autologous peripheral blood ce...

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PMC11604830

LPS was injected into the right striatum of five mice to induce inflammation.

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PMC11513011

In KK-47, DIB decreased the expression of N-cadherin at 50 nM and 100 nM and increased the expression of E-cadherin at 100 nM. In T24, DIB increased the expression of E-cadherin at 50 nM and 100 nM. In 5637, DIB decreased the expression of N-cadherin and Vimentin at 50 nM and 100 nM (Fig. 4A).

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PMC11795610

Keratin 14 mRNA. (

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PMC6190245

The cells were grown as monolayers in a 25-cm flask.

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PMC11683130

So we hypothesize that increased SerpinB3/B13 expression suppress TGM3 activation by inhibiting cathepsin L activity, thereby affecting cross-linking of the stratum corneum and resulting in impaired skin barrier.

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PMC11489351

Additionally, our results support prior work showing that LDHA activity increases with increased pHi (62) and suggests that changes in LDHA transcription, expression, and activity could synergize to support cellular metabolism changes.

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PMC11637276

Bafilomcyin A1, FR180204, PD98059, SB202190, and SB203580 from MedChem express.

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