PMCID
string | Sentences
string | ner
list |
|---|---|---|
PMC7153288
|
For isolating Streptomyces sp. SS1-1 from Catharanthus roseus, the plant was collected, transported to the laboratory and processed immediately within 2–3 h. Stems were cut with a size of 3 cm and thoroughly washed in running tap water to remove epiphytes and other adhered materials on the surface of the stem.
|
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PMC11129910
|
The vesicular trafficking machinery by RAB GTPases delivers vesicles of intracellular and extracellular cargos, including growth factors , nutrients, integrins , and other junction proteins, that control cellular signaling that controls growth, development , locomotion, and overall survival .
|
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PMC11585587
|
Then, the STRING database was used to analyze 58 interaction targets, obtain a PPI network, and generate a PPI relationship network diagram with 58 points and 160 edges.
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PMC11564322
|
Similarly, after the 48-h exposure, both studied peptides did not cause statistically significant changes in the cell number in the HL-60, K562, and MEG-A2 cell lines (Fig. 5A–C).Fig.
|
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PMC11055443
|
Yuan et al. showed the anti-inflammatory effect of these cells on bacterial infection caused by methicillin-resistant Staphylococcus aureus (32).
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PMC11283030
|
Cell proliferation was detected with CCK-8 assay, as previously described .
|
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PMC9429973
|
Overall response rate was 61.5% in the 1st group, 52.5% in the 2nd group and 83.3 % in the 3rd group (p=0.01).
|
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PMC7189327
|
Additionally, our functional analyses showed that PTCH1 played significant roles in cell proliferation and BCC pathway.
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PMC11033180
|
These results indicated that the cellular expression and distribution of Sema5A and PlexinA1/A2 in ENS in vitro model derived from embryonic rat gut were similar to those in gut tissue.
|
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PMC10047551
|
However, one should not ignore the fact that the regulation of PD-L1 on the transcriptional level can impact the amount of cell-surface-located PD-L1 .
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PMC9503541
|
Furthermore, in vitro cytotoxicity assays are typically accompanied by wound healing experiments to determine the efficiency and optimal dose of the tested agents.
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PMC9429973
|
There was totally 14.2% (48/417) patients with the mutation of U2AF1, of which 19.7%(29/147) in MDS-MF group and 10.0%(19/190) in MDS without MF group.
|
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PMC9429973
|
Y. Si, L. Yu, X. Yin, R. Xu, Z. Li, S. Cui Shandong University of Traditional Chinese Medicine; The Third Affiliated Hospital of Shandong First Medical University; Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China Background: Multiple myeloma (MM) is a common plasma cell malignant disease, the clonal evolution of myeloma cells and the immune escape caused by it are an important mechanism of refractory drug resistance.
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PMC9351137
|
D Mock, left panel; long intercellular bridges (LIB) right panel; no DAPI-stained trapped chromatin was observed.
|
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PMC9516401
|
The interplay between retinoblastoma proteins (RB) and IDE has been suggested to play fundamental roles in cell growth regulation (Radulescu et al., 2010 ▶).
|
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"O",
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PMC11627398
|
The study received approval from the Ethics Committee of the ZIBO Central Hospital (No. IEC-form-030-2.0).
|
[
{
"tags": [
"O",
"O",
"O",
"O",
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"O",
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PMC8956657
|
Phasing was performed using molecular replacement in Phaser MR, with PDB codes 7JJM and 6BVZ used as a search model for IMPα2 and IMPα3 respectively.
|
[
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"tags": [
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"respectively",
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]
}
] |
PMC9027909
|
In order to evaluate the expression level of miRNAs: mir-16, mir-21, mir-29a, mir-223, and mir-874, mature sequences of human miRNAs were selected from the miRBase database (https://www.mirbase.org/) according following accession numbers: MIMAT0000069, MIMAT0000076, MIMAT0000086, MIMAT0000280, and MIMAT0004911, respectively.
|
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PMC11674834
|
Also, it is discharged in the wastewater of pharmaceutical and pesticide companies .
|
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] |
PMC9545474
|
Briefly, 1.0×10 cells per well were seeded in a 6‐well plate and incubated for 24 at 37 °C and a 5 % CO2 humidified atmosphere.
|
[
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"tags": [
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"O",
"O",
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"O",
"O",
"O",
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"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
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"1.0",
"×",
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"cells",
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"plate",
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"°",
"C",
"and",
"a",
"5",
"%",
"CO2",
"humidified",
"atmosphere",
"."
]
}
] |
PMC6379402
|
All these data networks are compared to randomly generated networks coming from the following seven models that are commonly used in biology: The Erdös–Rènyi random graph model (ER) represents uniformly distributed random interactions between a set of nodes.
|
[
{
"tags": [
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"O",
"O",
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"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"between",
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"set",
"of",
"nodes",
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]
}
] |
PMC11632064
|
Interestingly, the unselective RSK inhibitor BI-D1870 clustered with both PLK1 KD and PLK1 inhibitors, further supporting the inhibition of PLK1 by this compound.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"O",
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"the",
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"of",
"PLK1",
"by",
"this",
"compound",
"."
]
}
] |
PMC9577200
|
with a thickness of 0.55–1.2 nm and a diameter of 0.5–3 μm.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
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"tokens": [
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"nm",
"and",
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"diameter",
"of",
"0.5–3",
"μm",
"."
]
}
] |
PMC8427838
|
Moesin binds directly to microtubules and regulates spindle organization in metaphase, cell morphogenesis during mitosis and cell polarity , suggesting that, by interacting with TMIGD1, moesin links TMIGD1 to microtubules and thus modulates cell polarity.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
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"to",
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"and",
"thus",
"modulates",
"cell",
"polarity",
"."
]
}
] |
PMC11767725
|
Network analysis revealed significant disruptions in microbial correlations at T8, reflecting transient community instability post-treatment.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
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"tokens": [
"Network",
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"correlations",
"at",
"T8",
",",
"reflecting",
"transient",
"community",
"instability",
"post-treatment",
"."
]
}
] |
PMC11787381
|
6Effects of formulated bambuterol in mice in the Morris water maze.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"6Effects",
"of",
"formulated",
"bambuterol",
"in",
"mice",
"in",
"the",
"Morris",
"water",
"maze",
"."
]
}
] |
PMC9429973
|
Using genetic approaches, we demonstrated that loss of SHP1 increases BCR signaling activity and sensitizes tumor cells to the inhibition by ibrutinib.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
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"tokens": [
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"and",
"sensitizes",
"tumor",
"cells",
"to",
"the",
"inhibition",
"by",
"ibrutinib",
"."
]
}
] |
PMC9856122
|
Multiple compounds were studied in vitro to investigate action against SARS-CoV-2 on the human epithelial colorectal adenocarcinoma cell line (Caco-2 cells).
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"Multiple",
"compounds",
"were",
"studied",
"in",
"vitro",
"to",
"investigate",
"action",
"against",
"SARS-CoV-2",
"on",
"the",
"human",
"epithelial",
"colorectal",
"adenocarcinoma",
"cell",
"line",
"(",
"Caco-2",
"cells",
")",
"."
]
}
] |
PMC11531744
|
In order to establish a reliable prognosis signature, batch effects of the TCGA, GETx and ICGC dataset were removed using the “sva” package in R software.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
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"establish",
"a",
"reliable",
"prognosis",
"signature",
",",
"batch",
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"TCGA",
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"GETx",
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"ICGC",
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"removed",
"using",
"the",
"“",
"sva",
"”",
"package",
"in",
"R",
"software",
"."
]
}
] |
PMC11673128
|
M1-like and M2-like macrophages were produced, in order to compare them with M0 macrophages in terms of SIRP-α expression.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"M1-like",
"and",
"M2-like",
"macrophages",
"were",
"produced",
",",
"in",
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"compare",
"them",
"with",
"M0",
"macrophages",
"in",
"terms",
"of",
"SIRP-α",
"expression",
"."
]
}
] |
PMC11754094
|
On the basis of the optimized long-range amplicon sequencing, we quantified large deletions and small indels induced by CRISPR-Cas9 nuclease in various human cell lines.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
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"tokens": [
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"basis",
"of",
"the",
"optimized",
"long-range",
"amplicon",
"sequencing",
",",
"we",
"quantified",
"large",
"deletions",
"and",
"small",
"indels",
"induced",
"by",
"CRISPR-Cas9",
"nuclease",
"in",
"various",
"human",
"cell",
"lines",
"."
]
}
] |
PMC11672142
|
To correlate the changes in cell viability with Fe uptake in the cells, the Fe levels in the media were measured in all of the samples (Figure S21).
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"To",
"correlate",
"the",
"changes",
"in",
"cell",
"viability",
"with",
"Fe",
"uptake",
"in",
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"cells",
",",
"the",
"Fe",
"levels",
"in",
"the",
"media",
"were",
"measured",
"in",
"all",
"of",
"the",
"samples",
"(",
"Figure",
"S21",
")",
"."
]
}
] |
PMC11769516
|
The multilayered mitochondrial network of antioxidant systems, consisting of many enzymes—glutathione transferase (GST), glutathione peroxidase (GPx), catalase (CAT), superoxide dismutase (SOD) and glutathione reductase (GR)— protects cellular systems .
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
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"tokens": [
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"superoxide",
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"SOD",
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"and",
"glutathione",
"reductase",
"(GR)—",
"protects",
"cellular",
"systems",
"."
]
}
] |
PMC11697065
|
A surprisingly small number of individual hits were identified as shared across productivity outcomes and might therefore be key drivers of enhanced antibody production.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
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"tokens": [
"A",
"surprisingly",
"small",
"number",
"of",
"individual",
"hits",
"were",
"identified",
"as",
"shared",
"across",
"productivity",
"outcomes",
"and",
"might",
"therefore",
"be",
"key",
"drivers",
"of",
"enhanced",
"antibody",
"production",
"."
]
}
] |
PMC11423992
|
Nevertheless, when compared to EC50 values obtained from these experimental findings, TFAB002s demonstrated approximately tenfold higher efficacy in inducing malignant B lymphocyte death in vitro .
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
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"tokens": [
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",",
"when",
"compared",
"to",
"EC50",
"values",
"obtained",
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",",
"TFAB002s",
"demonstrated",
"approximately",
"tenfold",
"higher",
"efficacy",
"in",
"inducing",
"malignant",
"B",
"lymphocyte",
"death",
"in",
"vitro",
"."
]
}
] |
PMC7504302
|
Three dimensional MPM models provide many advantages over 2D cultures as they better represent the major in vivo characteristics of tumors.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"Three",
"dimensional",
"MPM",
"models",
"provide",
"many",
"advantages",
"over",
"2D",
"cultures",
"as",
"they",
"better",
"represent",
"the",
"major",
"in",
"vivo",
"characteristics",
"of",
"tumors",
"."
]
}
] |
PMC3931643
|
ATP-competitive “active-site” mTOR inhibitors produce more complete mTOR inhibition and are more effective than rapamycin in preclinical models of leukemia, lymphoma and multiple myeloma.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"ATP-competitive",
"“",
"active-site",
"”",
"mTOR",
"inhibitors",
"produce",
"more",
"complete",
"mTOR",
"inhibition",
"and",
"are",
"more",
"effective",
"than",
"rapamycin",
"in",
"preclinical",
"models",
"of",
"leukemia",
",",
"lymphoma",
"and",
"multiple",
"myeloma",
"."
]
}
] |
PMC11736898
|
The inhibition of proliferation by VID400 also suggested a dose–response relationship, but this was only statistically significant in keloid keratinocytes; however, a trend for decreased proliferation with increased VID400 concentrations was observed in normal keratinocytes.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
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"tokens": [
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"of",
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"by",
"VID400",
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"a",
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"but",
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"significant",
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"however",
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"a",
"trend",
"for",
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"proliferation",
"with",
"increased",
"VID400",
"concentrations",
"was",
"observed",
"in",
"normal",
"keratinocytes",
"."
]
}
] |
PMC10565698
|
B. Prediction of correlation between miR-211-5p and mRNAs from the ENCORI database.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"B.",
"Prediction",
"of",
"correlation",
"between",
"miR-211",
"-",
"5p",
"and",
"mRNAs",
"from",
"the",
"ENCORI",
"database",
"."
]
}
] |
PMC11806182
|
In both survival curves, the green line represents high expression and the red line represents low expression Differences in tissue cellular composition in UCEC patients stratified by miR-330 expression.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"In",
"both",
"survival",
"curves",
",",
"the",
"green",
"line",
"represents",
"high",
"expression",
"and",
"the",
"red",
"line",
"represents",
"low",
"expression",
"Differences",
"in",
"tissue",
"cellular",
"composition",
"in",
"UCEC",
"patients",
"stratified",
"by",
"miR-330",
"expression",
"."
]
}
] |
PMC11753949
|
The calsarcin domain is also highly conserved in the synaptopodin paralogues synaptopodin 2 and synaptopodin 2-like, and extends to the hairpin region (67% similarity, Figure S3A).
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"The",
"calsarcin",
"domain",
"is",
"also",
"highly",
"conserved",
"in",
"the",
"synaptopodin",
"paralogues",
"synaptopodin",
"2",
"and",
"synaptopodin",
"2-like",
",",
"and",
"extends",
"to",
"the",
"hairpin",
"region",
"(",
"67",
"%",
"similarity",
",",
"Figure",
"S3A",
")",
"."
]
}
] |
PMC8973085
|
When 2-thioxopyridine-3-carbonitrile 3a,b was refluxed with derivatives of 2-chloro-N-arylacetamide 6a,b as 2-chloro-N-(4-fluorophenyl)acetamide or 2-chloro-N-(p-tolyl)acetamide in EtOH containing a catalytic amount of Et3N, the corresponding 2-(N-aryl)-carboxamidomethylthiopyridine derivatives 7a–7d were obtained, respectively (Scheme 3).
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
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"tokens": [
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"b",
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"Scheme",
"3",
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]
}
] |
PMC11525293
|
A431 (human epidermoid cell line; ATCC# CCL-1555) and A549 (human lung carcinoma cell line; ATCC# CCL-185) were kindly provided by Dr. Ada Sacchi (Istituto Nazionale Tumori Regina Elena, Rome, Italy), H1299 (human lung carcinoma cell line; ATCC# CRL-5803) was kindly provided by Dr. Giovanni Blandino (Istituto Nazionale Tumori Regina Elena, Rome, Italy), U-2 OS (human osteosarcoma cell line; ATCC# HTB-96) was kindly provided by Prof. Francesco Blasi (Università degli Studi di Milano, Milan, Italy), and HaCaT (human keratinocyte cell line) was kindly provided by Prof. Antonio Costanzo (Humanitas Research Hospital, Milan, Italy).
|
[
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"O",
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PMC11737091
|
p < 0.05; **, p < 0.01; ***, p < 0.001 To better understand the association between DBF4 expression levels and patient prognosis, survival curves were analysed by comparing ccRCC patients with higher DBF4 expression levels with ccRCC patients with lower DBF4 expression levels.
|
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}
] |
PMC11730311
|
In addition, potency of hAmylin and hCGRP was compared.
|
[
{
"tags": [
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"O",
"O",
"O",
"O",
"O",
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"and",
"hCGRP",
"was",
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]
}
] |
PMC11731614
|
Primary keratinocyte cultures were grown on 6-well plates (Fisherbrand FB012927) with a 300,000-seeding density and grown to 90% confluency.
|
[
{
"tags": [
"O",
"O",
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"O",
"O",
"O",
"O",
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"O",
"O",
"O",
"O",
"O",
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"O",
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"grown",
"to",
"90",
"%",
"confluency",
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]
}
] |
PMC5311252
|
Hierarchical clustering of 762 samples from BRCA patients and 87 normal samples based on the expression of the 275 oncomotif-miRNA signature genes defined in LUAD generated results that very closely mimicked the results in LUAD (Supplementary Figure 8a).
|
[
{
"tags": [
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"O",
"O",
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"O",
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"O",
"O",
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"8a",
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]
}
] |
PMC11701801
|
C, Percentage of annexin V–positive cells within the SMARCA4/SMARCA2-deficient and SS18–SSX fusion cell populations treated for 6 days with the indicated concentrations of CP-C27.
|
[
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"tags": [
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"O",
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]
}
] |
PMC11206251
|
Such observations might be due to the presence of biologically functional compounds in the PEIM.
|
[
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"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"O",
"O",
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"O",
"O",
"O",
"O"
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"due",
"to",
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"presence",
"of",
"biologically",
"functional",
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"in",
"the",
"PEIM",
"."
]
}
] |
PMC8316344
|
Recently, we revealed that PCBP2 is also positively regulated by TRIB2 ().
|
[
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"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"O",
"O"
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"tokens": [
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"we",
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"also",
"positively",
"regulated",
"by",
"TRIB2",
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}
] |
PMC11748335
|
The results indicated significant enrichment of DMVs in peaks within short LOCKs, while SINEs and LINEs were enriched in the peaks within long LOCKs (Fig. 1F).
|
[
{
"tags": [
"O",
"O",
"O",
"O",
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"O",
"O",
"O",
"O",
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}
] |
PMC11585254
|
The next day, cells were washed once with 100 μl phenol red-free DMEM containing 20 mM HEPES and then pretreated with vehicle (PBS) or CXCL13 (10 nM) for 1 hour at 37°C.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"O",
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"for",
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"hour",
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"37",
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"C",
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}
] |
PMC9429973
|
The rates of beta-thalassemia major may be prevented by proper screening for beta-thalassemia minor during the prenatal period.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
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"major",
"may",
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"prevented",
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"minor",
"during",
"the",
"prenatal",
"period",
"."
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}
] |
PMC11748335
|
Additionally, according to our predefined threshold (see Methods), a substantial proportion of tumor-gain H3K27me3 LOCKs within I- (23–40%) and L-PMDs (28–61%) exhibited enrichment of H3K9me3 modifications in normal cell lines.
|
[
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"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"O",
"O",
"O",
"O",
"O",
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"modifications",
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"cell",
"lines",
"."
]
}
] |
PMC9429973
|
B. Biderman, O. Gavrilina, O. Glinstchikova, T. Makarik, I. Fevraleva, D. Tikhomirov, T. Tupoleva, A. Sudarikov National Medical Research Center for Hematology, Moscow, Russia Background: March 2020 strict measures were introduced at the National Research Center for Hematology (Moscow, Russia) in order to prevent the spread of SARS-CoV-2: the mandatory wearing of masks, screening for the presence of symptoms of acute respiratory viral infections, regular PCR testing of all staff and patients, a ban on visiting patients, and cancellation of all face-to-face meetings of the employees.
|
[
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"O",
"O",
"O",
"O",
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"O",
"O",
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"O",
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"O",
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"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"O",
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"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"O",
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"meetings",
"of",
"the",
"employees",
"."
]
}
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PMC11711663
|
HHH GLDMDependenceVariance13.
|
[
{
"tags": [
"O",
"O",
"O"
],
"tokens": [
"HHH",
"GLDMDependenceVariance13",
"."
]
}
] |
PMC11705630
|
One possible explanation for this conflicting result is that previous studies employed different RCC cell line, 786-O, with basal expression level of GLDC lower than other RCC cell lines, and our study used ACHN and Caki-2 with basal expression levels of GLDC higher than other RCC cell lines.
|
[
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"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"B-CellLine",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"B-CellLine",
"O",
"B-CellLine",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
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"lines",
"."
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}
] |
PMC11087055
|
The cell spheres were then rinsed in serum-free DMEM and implanted into the anterior marginal zone in the chick embryonic discs at pre-streak stages.
|
[
{
"tags": [
"O",
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"O",
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"discs",
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"pre-streak",
"stages",
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}
] |
PMC11754784
|
Channels from left to right: Cy5 channel, TAMRA channel, FAM channel, bright-field overlay channel.
|
[
{
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"O",
"O",
"O",
"O",
"O",
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}
] |
PMC7192625
|
This is the case, for example, for heterochromatin, which shows high ChAs only with itself, moderate cross-ChAs with H3K27me3, and negative cross-ChAs with all other features.
|
[
{
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"features",
"."
]
}
] |
PMC11792888
|
As expected, for AIF-dependent apoptosis, no changes in the phosphorylation levels of P38 MAPK, ERK, or AKT were found upon venom treatment in the A549 cells (Figure 6).
|
[
{
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}
] |
PMC11024707
|
mi-RNA-106a-5p, mi-RNA-151a-3p, and mi-RNA-28-3p were found to be expressed significantly lower in the patient group compared to the control group.
|
[
{
"tags": [
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"O",
"O",
"O",
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]
}
] |
PMC11487720
|
We determined that the zinc finger domain of TRAF2 blocks the function of WWOX/p53 in inducing BCD at low temperatures.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
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"O",
"O",
"O",
"O",
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"at",
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"."
]
}
] |
PMC11806106
|
After reaching a plateau, the applied agonist was washed off with extracellular buffer (indicated with the arrow) (B).
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"O",
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"indicated",
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"arrow",
")",
"(",
"B",
")",
"."
]
}
] |
PMC9429973
|
Summary/Conclusion: More favorable prognostic features in AL could be NLR, the median of which is equal to or greater than 0.99.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"O",
"O",
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"O",
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"is",
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"to",
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"greater",
"than",
"0.99",
"."
]
}
] |
PMC11088135
|
However, the detailed pathogenesis of gliomas and effective treatments remain uncertain.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"of",
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"and",
"effective",
"treatments",
"remain",
"uncertain",
"."
]
}
] |
PMC11740207
|
We also discuss the potential implications of further research into these unique cellular stages for advancing leukemia and cancer treatment and prevention.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
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"tokens": [
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"advancing",
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"and",
"cancer",
"treatment",
"and",
"prevention",
"."
]
}
] |
PMC11534035
|
The results showed a significant difference, with PAI1 expression in the knockdown group measured at M=57.25±2.892% compared to the control group (100%, p<0.001).
|
[
{
"tags": [
"O",
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"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"O",
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"O",
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"100",
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",",
"p<0.001",
")",
"."
]
}
] |
PMC11721096
|
The pCDNA3.1 (+) vector was used to express human tyrosinase.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
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"The",
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"+",
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"vector",
"was",
"used",
"to",
"express",
"human",
"tyrosinase",
"."
]
}
] |
PMC11678448
|
Both GO and KEGG analyses employed hypergeometric tests to identify significantly enriched components among the differential genes compared to the background.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"Both",
"GO",
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"KEGG",
"analyses",
"employed",
"hypergeometric",
"tests",
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"identify",
"significantly",
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"components",
"among",
"the",
"differential",
"genes",
"compared",
"to",
"the",
"background",
"."
]
}
] |
PMC6379402
|
This makes the solver non-deterministic: on the same input data, different runs result in similar, but nonidentical solutions.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
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"tokens": [
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"non-deterministic",
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"on",
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"input",
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",",
"different",
"runs",
"result",
"in",
"similar",
",",
"but",
"nonidentical",
"solutions",
"."
]
}
] |
PMC11116779
|
After 96 h, 10 cells were gently re-suspended in 100 μL of binding buffer and incubated for 15 min at room temperature in the dark with 5 μL of Annexin-V-FITC and 5 μL of Propidium Iodide (PI).
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
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"tokens": [
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"and",
"5",
"μL",
"of",
"Propidium",
"Iodide",
"(",
"PI",
")",
"."
]
}
] |
PMC11721587
|
Left, Flag-tagged Fu or Fu∆Sufu condensates (P100) derived from Sf9 cells were resuspended and incubated with MPA in the presence of free Ci or Sufu-Ci purified from Sf9 cells, followed by immunoblot analysis with the indicated antibodies.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"O",
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"O",
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"O",
"O",
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"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"O",
"O",
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"cells",
",",
"followed",
"by",
"immunoblot",
"analysis",
"with",
"the",
"indicated",
"antibodies",
"."
]
}
] |
PMC11770199
|
Likewise, expression datasets were subjected to Gene Set Enrichment Analysis (GSEA).
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
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"tokens": [
"Likewise",
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"expression",
"datasets",
"were",
"subjected",
"to",
"Gene",
"Set",
"Enrichment",
"Analysis",
"(",
"GSEA",
")",
"."
]
}
] |
PMC11604830
|
A standard reference tube containing PFCE‐NE in low‐gelling agar (2.64 M of protons) was used for proton quantification.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"A",
"standard",
"reference",
"tube",
"containing",
"PFCE‐NE",
"in",
"low‐gelling",
"agar",
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"2.64",
"M",
"of",
"protons",
")",
"was",
"used",
"for",
"proton",
"quantification",
"."
]
}
] |
PMC11397654
|
Calixarene-based multivalent constructs featuring new biological or pharmacological properties have been extensively exploited in the glycobiology , gene delivery , controlled drug release , and antimicrobial medicine fields.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
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"constructs",
"featuring",
"new",
"biological",
"or",
"pharmacological",
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"exploited",
"in",
"the",
"glycobiology",
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"gene",
"delivery",
",",
"controlled",
"drug",
"release",
",",
"and",
"antimicrobial",
"medicine",
"fields",
"."
]
}
] |
PMC11323699
|
Therefore, mice showing no signs of tumor development (carcinosis, nodules, or ascites) at the time of euthanasia were excluded to avoid misinterpretation of the results.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
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"tokens": [
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"showing",
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"at",
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"were",
"excluded",
"to",
"avoid",
"misinterpretation",
"of",
"the",
"results",
"."
]
}
] |
PMC11609529
|
At 72 h post-infection, these two groups of transduced cells (1 × 10 cells/mouse) were intraperitoneally injected into NOD.SCID mice (n = 6/group, mean ± SD). (
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
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"=",
"6/group",
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"mean",
"±",
"SD",
")",
".",
"("
]
}
] |
PMC8633974
|
We propose that multi-exon gRNA TatDE disruption delivered by LNPs enables translation for animal and human testing.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
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"tokens": [
"We",
"propose",
"that",
"multi-exon",
"gRNA",
"TatDE",
"disruption",
"delivered",
"by",
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"enables",
"translation",
"for",
"animal",
"and",
"human",
"testing",
"."
]
}
] |
PMC8623816
|
For example, the Saccharomyces cerevisiae L-BC RNA replicase recognizes the 3′-UTR sequence of the Saccharomyces cerevisiae L-A virus .
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"For",
"example",
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"the",
"Saccharomyces",
"cerevisiae",
"L-BC",
"RNA",
"replicase",
"recognizes",
"the",
"3′-UTR",
"sequence",
"of",
"the",
"Saccharomyces",
"cerevisiae",
"L-A",
"virus",
"."
]
}
] |
PMC11727907
|
Evidence shows that Klotho regulates multiple mechanisms critical for maintaining the homeostasis and functions of retinal cells, and its depletion results in the gradual deterioration of retinal function , suggesting it is a potential therapeutic target for retinal degenerative diseases .
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
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"and",
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",",
"suggesting",
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]
}
] |
PMC10849234
|
While researchers have used NLCs derived from both HL-60 and PLB-985 cells for studies of degranulation [20–29] no studies have directly compared which cell line model and conditions are optimal for these studies.
|
[
{
"tags": [
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"O",
"O",
"O",
"O",
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"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"O",
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]
}
] |
PMC11750165
|
SP, signal peptide domain; DSL, Delta/Serrate/LAG-2 domain; CR, cysteine-rich domain; TM, transmembrane domain; AAA, AAA-ATPase domain.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"transmembrane",
"domain",
";",
"AAA",
",",
"AAA-ATPase",
"domain",
"."
]
}
] |
PMC11591794
|
The HeLa cell series were cultured in Eagle’s minimum essential medium (EMEM) (Sigma Aldrich, Darmstadt, Germany) and the HaCaT cell line was cultured in Dulbecco’s modified eagle medium (DMEM) (Invitrogen, Carlsbad, CA, USA) containing glutamine and penicillin-streptomycin solution, fetal bovine serum (FBS) (Gibco, Grand Island, NY, USA), and the cells were grown in sterile incubators at 37 °C and 5% CO2.
|
[
{
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"O",
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"O",
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"and",
"5",
"%",
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]
}
] |
PMC11541409
|
Journal of Clinical Oncology, 2024.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"Journal",
"of",
"Clinical",
"Oncology",
",",
"2024",
"."
]
}
] |
PMC8193813
|
The Midland boilers are fire-tube-type boilers using low-pressure utility-supplied natural gas.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"tokens": [
"The",
"Midland",
"boilers",
"are",
"fire-tube-type",
"boilers",
"using",
"low-pressure",
"utility-supplied",
"natural",
"gas",
"."
]
}
] |
PMC11683130
|
However, one study found that SerpinB7 expression was down-regulated in psoriatic skin lesions, and its expression level is negatively correlated with the severity of the patient’s disease (150).
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"of",
"the",
"patient",
"’s",
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"(",
"150",
")",
"."
]
}
] |
PMC10631132
|
Monolayer-based (MB) differentiation showed either no significant increase or an initial Ct value below the detection threshold.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"value",
"below",
"the",
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}
] |
PMC11684269
|
However, rather than increasing NAD/NADH, supplementing 2-KG restores the antiviral capacity of CD8 T cells (66).
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"O",
"O",
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"O",
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"CD8",
"T",
"cells",
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"66",
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"."
]
}
] |
PMC8623816
|
To investigate whether the mycovirus was responsible for this impaired growth, we first attempted to eliminate it from the fungal host by hyphal tipping and ribavirin treatment.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"and",
"ribavirin",
"treatment",
"."
]
}
] |
PMC10955424
|
In contrast, only one of the four cirrhosis ascites was active in conferring OC platinum chemoresistance, while the other three were inactive (Fig. 1).
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"while",
"the",
"other",
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"were",
"inactive",
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"Fig.",
"1",
")",
"."
]
}
] |
PMC10654497
|
Protein–protein interactions between SFRGs. (
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"Protein",
"–",
"protein",
"interactions",
"between",
"SFRGs",
".",
"("
]
}
] |
PMC7642379
|
Moreover, the expression levels of KMO was comparably low in all cell lines but did not correlate with gene copy number.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"Moreover",
",",
"the",
"expression",
"levels",
"of",
"KMO",
"was",
"comparably",
"low",
"in",
"all",
"cell",
"lines",
"but",
"did",
"not",
"correlate",
"with",
"gene",
"copy",
"number",
"."
]
}
] |
PMC11257988
|
Kruspig et al. demonstrated through experiments that the initiation and progression of KRAS-driven lung tumors require the involvement of ERBB family receptor tyrosine kinases (RTKs), and inhibition of the ERBB network weakens the activation of a series of downstream signaling proteins (such as pERK, STAT3, etc.),
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
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"lung",
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"the",
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"of",
"ERBB",
"family",
"receptor",
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"RTKs",
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"and",
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"the",
"activation",
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"of",
"downstream",
"signaling",
"proteins",
"(",
"such",
"as",
"pERK",
",",
"STAT3",
",",
"etc",
".",
")",
","
]
}
] |
PMC11361748
|
The distribution of TAR11 scores in single cells of lesional PSOR (Fig 9A) and HS skin (Fig 9D) is quasi-normal.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
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"TAR11",
"scores",
"in",
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"Fig",
"9A",
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"and",
"HS",
"skin",
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"Fig",
"9D",
")",
"is",
"quasi-normal",
"."
]
}
] |
PMC11740907
|
To gain a comprehensive understanding, an extensive literature survey was conducted to identify three pivotal proteins CDK2, PKB-α, and EGFR that regulate distinct signaling pathways in HeLA cells.88,89 Subsequently, molecular docking was employed to unveil the mechanism underpinning the anti-proliferative potential of POM.Figure 9Docking generated complexes of POM bonded to its corresponding molecular target CDK2 (hydrophobic, light blue), PCG (green, yellow) and EGFR (slate, purple): (A and E) CDK2-POM, (C and F) POM-PKB-α, (D and G) EGFR-POM.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"B-CellLine",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"tokens": [
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"a",
"comprehensive",
"understanding",
",",
"an",
"extensive",
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"to",
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"three",
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"CDK2",
",",
"PKB-α",
",",
"and",
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"the",
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"complexes",
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"its",
"corresponding",
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"CDK2",
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"and",
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"CDK2-POM",
",",
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"F",
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"POM-PKB-α",
",",
"(",
"D",
"and",
"G",
")",
"EGFR-POM",
"."
]
}
] |
PMC11655536
|
F Cell viability of RPMI-8226 cells.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"B-CellLine",
"O",
"O"
],
"tokens": [
"F",
"Cell",
"viability",
"of",
"RPMI-8226",
"cells",
"."
]
}
] |
PMC9429973
|
Western blot analysis reveals the expression changes of histone H3K36me3 methyltransferase SETD2 among control, ALKBH5, ALKBH5SNHG15 group MM RPMI8226 cells.
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"B-CellLine",
"O",
"O"
],
"tokens": [
"Western",
"blot",
"analysis",
"reveals",
"the",
"expression",
"changes",
"of",
"histone",
"H3K36me3",
"methyltransferase",
"SETD2",
"among",
"control",
",",
"ALKBH5",
",",
"ALKBH5SNHG15",
"group",
"MM",
"RPMI8226",
"cells",
"."
]
}
] |
PMC11637276
|
Interestingly, we found that the inhibition of lysosomal function significantly reduced both velocity and directionality of cell migration (S11 Fig).
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"Interestingly",
",",
"we",
"found",
"that",
"the",
"inhibition",
"of",
"lysosomal",
"function",
"significantly",
"reduced",
"both",
"velocity",
"and",
"directionality",
"of",
"cell",
"migration",
"(",
"S11",
"Fig",
")",
"."
]
}
] |
PMC11765678
|
1400W was effective in inhibiting the effects of ER (Figure 4B).
|
[
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"1400W",
"was",
"effective",
"in",
"inhibiting",
"the",
"effects",
"of",
"ER",
"(",
"Figure",
"4B",
")",
"."
]
}
] |
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