OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC8316344	Notably, such effects could be reversed by simultaneously expressing a TRIB2-sg-resistant TRIB2 (Fig. 2D–F).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notably", ",", "such", "effects",...
PMC11703992	The CD4+ Memory T cells were then divided into DDIT4 ± or ARHGAP15 ± groups, and further single-cell analysis indicated the differences in aspects involving intercellular communication, functional pathways, protein activity, metabolism and drug sensitivity between positive and negative groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11541241	Transgenic HIGS is now being studied and discovered to be an effective method for plant disease control (Kuo & Falk, 2020).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11269792	CircAPP and CDV3-3′UTR wild-type sequences (WT-circAPP, WT-CDV3) or mutant sequences (MUT-circAPP, MUT-CDV3) containing the miR-6838-5p binding site were cloned into the vector psiCHECK-2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9436459	The successful transformation from chalcomoracin (5) to wittiorumin F (18) under 5% CF3COOH undoubtedly allowed the determination of the absolute configuration of 18 , and it was regarded as a model compound for ECD and specific rotations analysis to determine the absolute configuration of morbilisin E (19) , inethermu...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8728081	The confocal images demonstrated that particles were adsorbed on the cell membrane.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "confocal", "images", "demonstrated", "that", "particles", "were", "adsorbed", ...
PMC10530622	Glycine is metabolized into glyoxylate by D-amino oxidase (DAO) and glutamate glyoxylate aminotransferase (GGAT).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Glycine", "is", "metabolized", "into", ...
PMC9917080	However, a single injection of sorafenib encapsulated in lipid nanocapsules (LNC-SFN) at a concentration of 3.5 μg/mouse leads to more pronounced anticancer effects .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11787355	Data are presented as mean values ± SEM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "presented", "as", "mean", "values", "±", "SEM", "." ] } ]
PMC9429973	Aims: This study aimed to summarize papers that analyzed patients with liver cirrhosis who were diagnosed with aggressive lymphoma.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "This", "s...
PMC11682224	Temperature/humidity is controlled at (26 ± 2)ºC/40–60% with a light/dark cycle of 12 h/12 h. The mice have access to autoclaved SPF-grade food and ultrafiltered purified water.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7215832	RX-3117 is a novel cytidine analog modified in the sugar ring moiety (Figure 1), which has shown promising anti-tumor activity against gemcitabine resistant xenografts from different pathologies and is currently in clinical trial (NCT02030067) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11075223	Cimicifugae Rhizoma has a strong anti-inflammatory effect due to its main efficacy in heat-clearing and detoxifying .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cimicifugae", "Rhizoma", "has", "a", "strong", "anti-i...
PMC9960565	C 20.42, H 4.15, N 12.21, found: C 33.73, H 6.56, N 12.01 (hygroscopic compound).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "C", ...
PMC11055510	In recent years, multiple circRNAs have been identified as tumor markers of OC (Sheng et al., 2020).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "recent", "y...
PMC10454535	Protein was transferred to Immun-Blot PVDF membranes (Bio-Rad Laboratories) for 7 min at 2.5 A using the mixed molecular weight setting on the Trans-Blot Turbo transfer system (Bio-Rad Laboratories).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9046263	Using primer3, two sets of primers for the HML-6 envelope locus ERVK3-1 were established (https://primer3.ut.ee) and validated for target specificity for the chromosome 19 locus using UCSC in-silico PCR (hg38).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11267830	b Fluorescence images of mice captured at four distinct time points.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "b", "Fluorescence", "images", "of", "mice", "captured", "at", "four", "distinct", "ti...
PMC10772747	To address this challenge, research intended for the development of effective drugs for breast cancer treatment is very crucial.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "address", "this", ...
PMC11711127	This study demonstrated that naive T cells possess a basal nuclear level of the NF-κB transcription factor, which played a pivotal role in maintaining IL-7R expression, ensuring their survival (36).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7868205	The concentration of AgNPs in the hydrosol was equivalent to 38.629 ng, as per ICP-OES analysis (19.51 μg/mL).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "concentration", ...
PMC8592717	XBJ is also effective in the treatment of patients with severe acute pancreatitis (SAP).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "XBJ", "is", "also", "effective", "in", "the", "t...
PMC11629461	Of the three NOX5 chromophores of NAD(P)H, FAD, heme, only FAD and NADPH are effective photosensitizers, with quantum yield (ФΔO2) of FAD 0.07 and NADPH ≥0.1. ,	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9014716	The influence of drugs on cell viability was determined with the Cell Counting Kit-8 assay (CCK-8; MedChemExpress, Monmouth Junction, NJ, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8382973	Alterations in the normal rectovaginal microbiota can lead to multiple rectovaginal infections and affect the risk of rectovaginal HIV transmission.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Alterations", "in", "the", ...
PMC7369657	DCFH reacts with ROS to form the fluorescent product 2′,7′-dichlorofluorescein (DCF, green fluorescence) which can be measured as an indication of the amount of intracellular ROS .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11320834	Liposomes were prepared according to previously described methods with modifications .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Liposomes", "were", "prepared", "according", "to", "previously", "described", "methods", "with", ...
PMC8270637	H9 cells were harvested and lysed in lysis buffer.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "H9", "cells", "were", "harvested", "and", "lysed", "in", "lysis", "buffer", "." ] } ]
PMC11786767	To quantify the movement of the biotin-DHPE signals toward the chromosomal interior, we performed line scanning as described in Fig. 2 to determine the ratio between the lowest biotin-DHPE signal within chromosomes and the biotin-DHPE signal at chromosome edges, that is, the inner/edge ratio of DHPE signal (Fig. 3B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Moreover, these clones were composed of cells with additional aberrations defining a number of separate subclones.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "these", "clones", "were", ...
PMC11665584	No Activated HF and significantly fewer Activated Suprabasal 1 and 2 cells were found in control epidermis distant from the wound edge, its unwounded IFE being constituted by populations of healthy Basal (Col17a1, Hist1h1b) and Suprabasal (Krt77, Egfr) keratinocytes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11588085	Upper panels represent results without ABC transporter inhibitor Reserpine, and Bottom panels represent results from cells treated with 15 µM of Reserpine (negative control).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11730311	We highlight benefits by increasing the lipid length to conjugated hαCGRP8-37 analogues, and that lipidation at the LLSR motif may lead to superior half-lives compared to positions further towards the C-terminus.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7887261	The DNA damageome also includes LoF variants that show DNA damage-up phenotypes, most of which are not directly related to DNA repair but rather participate in the DNA damage production.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9895440	PT.58.v.45621572).	[ { "tags": [ "O", "O", "O" ], "tokens": [ "PT.58.v.45621572", ")", "." ] } ]
PMC10198699	Since cell lines fall outside the NHA’s trade ban, the research institution would be free to commercialize the cell line.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Since", "cel...
PMC9429973	J. Martínez-López, P. Moreau, S. Z. Usmani, A. Garfall, N. W. van de Donk, J. F. San-Miguel, A. Oriol, A. Chari, L. Karlin, M.-V. Mateos, R. Popat, A. K. Nooka, S. Sidana, D. Trancucci, R. Verona, S. Girgis, C. Uhlar, T. Stephenson, A. Banerjee, A. Krishnan Haematological Malignancies Clinical Research Unit, Hospital 1...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11748618	To do this, we accessed genotype data from the African ancestry component of the ICGH spVL cohort (N = 3,886) and selected genetic variants in LD to the top associated HIV spVL variant in the chromosome 1 region, rs59784663-A-G (r ≥ 0.2, N = 121) and annotated them with HaploRegv4.2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10040136	The density plot of the proportion of MSCs amongst 50 cases is graphically represented.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "density", "plot", "of", "the", "proportion", "of", "MSCs"...
PMC11499381	The technical replicates within an experiment were then averaged to create a mean value for the biological replicate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "technical", "replicates", "within", ...
PMC8708099	no. 653964200); FXF was dissolved in 8% dimethyl sulfoxide (DMSO; Sigma Aldrich, St. Louis, MO, USA, cat.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11791432	To explore the relationship between ANXA1 expression and the response to additional therapy, we screened patients who received radiotherapy and/or chemotherapy after surgery and performed survival analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11502962	The MIF/CXCR4 axis is the most ligand–receptor interaction between macrophages and tumor cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "MIF/CXCR4", "axis", "is", "the", "most", "ligand", ...
PMC9429973	The literature search was conducted in May 2021 and was not restricted to a specific start date.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "literature", "search", "was", "conducted",...
PMC11515150	T-cell acute lymphoblastic leukemia (T-ALL) accounts for approximately 15% of childhood and 25% of adult ALL, respectively .	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "T-cell", ...
PMC11640476	In fact, several papers identified data inconsistencies in pre-clinical studies .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "fact", ",", "several", "papers", "identified", "data", "inconsistencies", "in", ...
PMC11761919	After incubating in simulated gastrointestinal fluid for 7 h, survival rate of bacteria in three prepared microcapsules was 49.36%, 38.04% and 33.78%, respectively. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11271278	WGS analysis showed translocations among these gene loci (Fig. S6C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "WGS", "analysis", "showed", "translocations", "among", "these", "gene", "loci", ...
PMC9429973	Data returns from 2018-2021 relating to NGS gene content and panel analysis were evaluated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "returns", "from", "2018", "-", "2021", "...
PMC9848491	We also established the predictive signature of ER stress-related lncRNA in DFS to further clarify the role of DFS in the prognosis of patients in UCEC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11774251	To further elucidate the mechanism of Tan-I in treating psoriasis, we performed RNA-seq on lesional skin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "further", "elucidate", "the", "mechanism", ...
PMC10551595	Effect of GinA on (A) CCRF‐CEM and RCCRF‐CEM T‐ALL cell, (B) NALM6 and RN95 B‐ALL cell lines, in addition to (C) normal mononuclear cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", ...
PMC11711871	In our study, the assessment of the aortic vasoreactivity revealed changes in the response of vascular rings to phenylephrine and DEA/NO, but not to KCl and acetylcholine, although Emax and EC50 were not significantly different between groups and diet conditions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11317131	PBS, trypsin, and Opti-MEM were purchased from Gibco.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PBS", ",", "trypsin", ",", "and", "Opti-MEM", "were", "purchased", "from", "Gibco", "." ...
PMC10033453	This could have slowed viral replication down to tip the balance in favor of cancer cell replication.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "could", "have", "slowed", "viral", ...
PMC9817179	The fixation artifact of an LLPS system can be represented as the absolute change in punctate percentage, or the ratio of in-puncta POI to total POI, after fixation:(1)ΔPunctate Percentage=Final Punctate Percentage−Initial Punctate Percentage=([S3 ]t=∞[S3 ]t=∞+[S4 ]t=∞−[S1 ]t=0[S1 ]t=0+[S2 ]t=0)∗100 (A) Schematic that ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	We cross-referenced differentially expressed (DE) metabolites with DE genes (3’ RNAseq) in a matched set of samples to identify important biological pathways.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Relapse occurred in 25.7% of the patients, 31.9% in the group w/IO and 20.7% w/o IO (p=0.26).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Relapse...
PMC11763126	E IP assay confirmed that CBDP1 can bind to YTHDF2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "E", "IP", "assay", "confirmed", "that", "CBDP1", "can", "bind", "to", "YTHDF2", "." ] ...
PMC11640247	Notably, RAC3 is integral to several key aspects of neuronal development, including neurite extension, axonal and dendritic formation, synaptogenesis, and neuronal migration .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11661040	MG63 and 143B cells were seeded in 6-well plates, and the cells were transfected with 20 nM siRNAs using Lipofectamine 2000 reagent according to the manufacturer’s instructions.	[ { "tags": [ "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC9325715	The maximum of the corresponding band shifted from 1391 to 1385 cm after iron incorporation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "maximum", "of", "the", "corresponding", "band", "shi...
PMC11495567	These results support the potential use of the PCAIs as targeted therapies against cancers with KRAS mutations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "results", "support", "the", "potential",...
PMC7987994	Three triplicates were used for each sample.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Three", "triplicates", "were", "used", "for", "each", "sample", "." ] } ]
PMC11643491	Although the mean of the AR is highest for the stretch ratio 1.4–1.7, there is a large distribution in the AR of those particles (Figure 1C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Median follow-up (patients alive) was 70.2 (46.3-83.5) months.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Median", "follow-up", "(", "patients", "alive", ")", "was", "70....
PMC9429973	When TN pts with ASXL1 were considered apart, having a ratio <1.31 retained its inferior prognostic impact compared to the ratio ≥1.31 group (median OS 57 vs 104 months, p<0.0453; HR 1.8 [1-3.2]), with TN/ASXL1 pts being associated with the worst outcome (median OS 24 months) (Fig.1C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9031474	In this review, we will focus on bicyclic drimane and coloratane sesquiterpenoids.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "this", "review", ",", "we", "will", "focus", "on", "bicyclic", ...
PMC6799808	Caspase-dependent and caspase-independent apoptosis can be induced under different conditions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Caspase-dependent", "and", "caspase-independent", "apoptosis", "can", "be", "induced", "under", "diffe...
PMC9429973	Aims: QuANTUM-First aimed to determine if the addition of Quiz to standard induction (IND) and post remission (including allogeneic hematopoietic cell transplant [allo-HCT]) in first complete remission [CR1]) consolidation followed by single-agent continuation therapy for up to 3 years improved survival compared with c...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11718109	Scale bar, 500 nm.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", ",", "500", "nm", "." ] } ]
PMC11653533	Ficus serves as a reservoir for numerous phytochemicals, showcasing a rich diversity of bioactive compounds within its structure (Fig. 4, Fig. 5).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11769516	They are mainly related to the increase in oxidative stress in neuronal cells, which leads to higher levels of pro-inflammatory cytokines as IL-1β, IL-6 and TNF-α, enzymatic activity as GST, GPx, CAT and SOD and neurotransmitter dysfunction (5-HT, serotonin, dopamine and GABA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11387401	Three ASOs per target gene were designed with the LNCASO online webtool (sequences in Appendix Table S8).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Three", "ASOs", "per", "target", ...
PMC11337594	Fig. 1TER inhibits cell viability and induces apoptosis in melanoma cells. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "1TER", "inhibits", "cell", "viability", "and", "induces", "apoptosis", "...
PMC11473843	Relative cell number of HBEC3-FAK KO cell line transduced as in (D); n = 3. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Relative", "cell", "number", "of"...
PMC11730311	For estimation of half-lives, experimental units are denoted as n = 1 and correspond to a single mouse IV dosed with compound.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", ...
PMC5941560	Note that these query descriptions are abbreviations of more detailed search terms, which are provided in the “Methods” section Jurkat publication trends.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC8009078	The hydrogen bonds formed by each ligand with TMPRSS2 in each frame were calculated and it is given in Fig. 8.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "hydrogen", ...
PMC11704135	in a dark environment.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "in", "a", "dark", "environment", "." ] } ]
PMC11345828	The resultant product was N-methylated using General Procedure D followed by saponification following General Procedure G (30 mg, 64% yield over 2 steps).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4839679	Renal cell carcinoma (RCC) is the most common (~80%) and lethal type of kidney cancer in adults with clear cell RCC (ccRCC) as the most prevalent and aggressive subtype .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11489351	Normal epithelial cells have an intracellular pH (pHi) of ∼7.2, but transient changes in pHi (6.8–7.6) have been shown to regulate cell behaviors, including cell migration (1), proliferation (2, 3), and differentiation (4) (Fig. 1A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10291556	Recently, it has been shown both in vitro and in vivo that in contrast to cisplatin, oxaliplatin and its analogues induce immunogenic cell death (ICD) and thereby synergistically potentiate antitumor effects.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11397654	IC50 was found to be 12.95 μM for 33a and 16.13 μM for 33b against the DLD-1 cell line.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "IC50", "was", "found", "...
PMC10747160	SARS-CoV-2 Wuhan nCov-19 strain (NCBI Reference Sequence: NC_045512.2) spike pseudotyped lentiviral virions were produced as previously described .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SARS-CoV-2", "Wuhan", "nCov-...
PMC11240571	Specifically, it has been reported that RT activates host immunity induced by immunogenic cell death , induces IFN-γ that leaves dendritic cells, and stimulates innate immunity associated with IFN pathway activity , as well as inducing chemokines and adhesion factors involved in T cell migration and infiltration .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11653168	The present findings may pave the way for further clinical investigations into Stattic and emphasize the importance of targeting dysregulated STAT3 signaling in leukemia therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11200978	When the combination of gemcitabine pretreatment and a single −15 °C freeze was applied, a significant increase in the necrotic cell population with a corresponding decrease in live cells was observed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10812665	They arrest their cell cycle, express biochemical markers of dopaminergic neurons, and develop a neurite network .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "They", "arrest", "their", "cell", "cyc...
PMC9429973	Aims: To investigate the pathophysiological basis of iron overload in PKD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "To", "investigate", "the", "pathophysiological", "basis", "of", "ir...
PMC11615218	TCR repertoire can be used as a surrogate for the T-cell clonotype and expansion .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TCR", "repertoire", "can", "be", "used", "as", "a", "surrogate",...
PMC10530622	RNAi is a natural process that involves the suppression of gene expression using small interfering RNA (siRNA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RNAi", "is", "a", "natural", ...
PMC9429973	Patient NK cells demonstrated decreased levels of KIRs (CD158a and CD158b) compared to HC (16.2±5 vs 33.8±2.1; p<0.01 and 17.6±6 vs 32.4±3.1; p<0.01, respectively), despite being exclusively CD56, and as such expected to highly express KIRs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11279598	Manuka honey (MH) is a monofloral honey that is produced from the nectar collected by honey bees (Apis Mellifera) when they pollinate the Manuka tea tree (Leptospermum scoparium).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11758416	Addition of concanamycin A reduced the level of L cell death in TCR-stimulated CD8 T cell conditions, but not in unstimulated conditions (Figure 3E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11033180	Whether Sema5A-induced synapsin 1 clustering in enteric neurons is achieved through regulation of O-glycosylation or homo- and heterodimerization of synapsin 1 remains to be studied.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	Many patients lose response over time, highlighting an unmet need for novel therapies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Many", "patients", "lose", "response", "over", "time", ",", "hig...
PMC9895440	24 h later, NY-ESO-1 TCR lentiviral particles produced as described above were added at a multiplicity of infection (MOI) of 2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11055510	Compared with the si-nc group, the cell healing rate in the si-circMAN1A2 group was significantly reduced (Fig. 2G).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Compared", "...

PMC8316344

Notably, such effects could be reversed by simultaneously expressing a TRIB2-sg-resistant TRIB2 (Fig. 2D–F).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notably", ",", "such", "effects",...

PMC11703992

The CD4+ Memory T cells were then divided into DDIT4 ± or ARHGAP15 ± groups, and further single-cell analysis indicated the differences in aspects involving intercellular communication, functional pathways, protein activity, metabolism and drug sensitivity between positive and negative groups.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11541241

Transgenic HIGS is now being studied and discovered to be an effective method for plant disease control (Kuo & Falk, 2020).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11269792

CircAPP and CDV3-3′UTR wild-type sequences (WT-circAPP, WT-CDV3) or mutant sequences (MUT-circAPP, MUT-CDV3) containing the miR-6838-5p binding site were cloned into the vector psiCHECK-2.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9436459

The successful transformation from chalcomoracin (5) to wittiorumin F (18) under 5% CF3COOH undoubtedly allowed the determination of the absolute configuration of 18 , and it was regarded as a model compound for ECD and specific rotations analysis to determine the absolute configuration of morbilisin E (19) , inethermu...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8728081

The confocal images demonstrated that particles were adsorbed on the cell membrane.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "confocal", "images", "demonstrated", "that", "particles", "were", "adsorbed", ...

PMC10530622

Glycine is metabolized into glyoxylate by D-amino oxidase (DAO) and glutamate glyoxylate aminotransferase (GGAT).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Glycine", "is", "metabolized", "into", ...

PMC9917080

However, a single injection of sorafenib encapsulated in lipid nanocapsules (LNC-SFN) at a concentration of 3.5 μg/mouse leads to more pronounced anticancer effects .

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PMC11787355

Data are presented as mean values ± SEM.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "presented", "as", "mean", "values", "±", "SEM", "." ] } ]

PMC9429973

Aims: This study aimed to summarize papers that analyzed patients with liver cirrhosis who were diagnosed with aggressive lymphoma.

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PMC11682224

Temperature/humidity is controlled at (26 ± 2)ºC/40–60% with a light/dark cycle of 12 h/12 h. The mice have access to autoclaved SPF-grade food and ultrafiltered purified water.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7215832

RX-3117 is a novel cytidine analog modified in the sugar ring moiety (Figure 1), which has shown promising anti-tumor activity against gemcitabine resistant xenografts from different pathologies and is currently in clinical trial (NCT02030067) .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11075223

Cimicifugae Rhizoma has a strong anti-inflammatory effect due to its main efficacy in heat-clearing and detoxifying .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cimicifugae", "Rhizoma", "has", "a", "strong", "anti-i...

PMC9960565

C 20.42, H 4.15, N 12.21, found: C 33.73, H 6.56, N 12.01 (hygroscopic compound).

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PMC11055510

In recent years, multiple circRNAs have been identified as tumor markers of OC (Sheng et al., 2020).

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PMC10454535

Protein was transferred to Immun-Blot PVDF membranes (Bio-Rad Laboratories) for 7 min at 2.5 A using the mixed molecular weight setting on the Trans-Blot Turbo transfer system (Bio-Rad Laboratories).

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PMC9046263

Using primer3, two sets of primers for the HML-6 envelope locus ERVK3-1 were established (https://primer3.ut.ee) and validated for target specificity for the chromosome 19 locus using UCSC in-silico PCR (hg38).

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PMC11267830

b Fluorescence images of mice captured at four distinct time points.

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PMC10772747

To address this challenge, research intended for the development of effective drugs for breast cancer treatment is very crucial.

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PMC11711127

This study demonstrated that naive T cells possess a basal nuclear level of the NF-κB transcription factor, which played a pivotal role in maintaining IL-7R expression, ensuring their survival (36).

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PMC7868205

The concentration of AgNPs in the hydrosol was equivalent to 38.629 ng, as per ICP-OES analysis (19.51 μg/mL).

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PMC8592717

XBJ is also effective in the treatment of patients with severe acute pancreatitis (SAP).

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PMC11629461

Of the three NOX5 chromophores of NAD(P)H, FAD, heme, only FAD and NADPH are effective photosensitizers, with quantum yield (ФΔO2) of FAD 0.07 and NADPH ≥0.1. ,

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PMC9014716

The influence of drugs on cell viability was determined with the Cell Counting Kit-8 assay (CCK-8; MedChemExpress, Monmouth Junction, NJ, USA).

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PMC8382973

Alterations in the normal rectovaginal microbiota can lead to multiple rectovaginal infections and affect the risk of rectovaginal HIV transmission.

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PMC7369657

DCFH reacts with ROS to form the fluorescent product 2′,7′-dichlorofluorescein (DCF, green fluorescence) which can be measured as an indication of the amount of intracellular ROS .

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PMC11320834

Liposomes were prepared according to previously described methods with modifications .

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PMC8270637

H9 cells were harvested and lysed in lysis buffer.

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PMC11786767

To quantify the movement of the biotin-DHPE signals toward the chromosomal interior, we performed line scanning as described in Fig. 2 to determine the ratio between the lowest biotin-DHPE signal within chromosomes and the biotin-DHPE signal at chromosome edges, that is, the inner/edge ratio of DHPE signal (Fig. 3B).

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PMC9429973

Moreover, these clones were composed of cells with additional aberrations defining a number of separate subclones.

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PMC11665584

No Activated HF and significantly fewer Activated Suprabasal 1 and 2 cells were found in control epidermis distant from the wound edge, its unwounded IFE being constituted by populations of healthy Basal (Col17a1, Hist1h1b) and Suprabasal (Krt77, Egfr) keratinocytes.

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PMC11588085

Upper panels represent results without ABC transporter inhibitor Reserpine, and Bottom panels represent results from cells treated with 15 µM of Reserpine (negative control).

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PMC11730311

We highlight benefits by increasing the lipid length to conjugated hαCGRP8-37 analogues, and that lipidation at the LLSR motif may lead to superior half-lives compared to positions further towards the C-terminus.

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PMC7887261

The DNA damageome also includes LoF variants that show DNA damage-up phenotypes, most of which are not directly related to DNA repair but rather participate in the DNA damage production.

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PMC9895440

PT.58.v.45621572).

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PMC10198699

Since cell lines fall outside the NHA’s trade ban, the research institution would be free to commercialize the cell line.

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PMC9429973

J. Martínez-López, P. Moreau, S. Z. Usmani, A. Garfall, N. W. van de Donk, J. F. San-Miguel, A. Oriol, A. Chari, L. Karlin, M.-V. Mateos, R. Popat, A. K. Nooka, S. Sidana, D. Trancucci, R. Verona, S. Girgis, C. Uhlar, T. Stephenson, A. Banerjee, A. Krishnan Haematological Malignancies Clinical Research Unit, Hospital 1...

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PMC11748618

To do this, we accessed genotype data from the African ancestry component of the ICGH spVL cohort (N = 3,886) and selected genetic variants in LD to the top associated HIV spVL variant in the chromosome 1 region, rs59784663-A-G (r ≥ 0.2, N = 121) and annotated them with HaploRegv4.2.

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PMC10040136

The density plot of the proportion of MSCs amongst 50 cases is graphically represented.

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PMC11499381

The technical replicates within an experiment were then averaged to create a mean value for the biological replicate.

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PMC8708099

no. 653964200); FXF was dissolved in 8% dimethyl sulfoxide (DMSO; Sigma Aldrich, St. Louis, MO, USA, cat.

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PMC11791432

To explore the relationship between ANXA1 expression and the response to additional therapy, we screened patients who received radiotherapy and/or chemotherapy after surgery and performed survival analysis.

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PMC11502962

The MIF/CXCR4 axis is the most ligand–receptor interaction between macrophages and tumor cells.

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PMC9429973

The literature search was conducted in May 2021 and was not restricted to a specific start date.

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PMC11515150

T-cell acute lymphoblastic leukemia (T-ALL) accounts for approximately 15% of childhood and 25% of adult ALL, respectively .

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PMC11640476

In fact, several papers identified data inconsistencies in pre-clinical studies .

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PMC11761919

After incubating in simulated gastrointestinal fluid for 7 h, survival rate of bacteria in three prepared microcapsules was 49.36%, 38.04% and 33.78%, respectively. (

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PMC11271278

WGS analysis showed translocations among these gene loci (Fig. S6C).

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PMC9429973

Data returns from 2018-2021 relating to NGS gene content and panel analysis were evaluated.

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PMC9848491

We also established the predictive signature of ER stress-related lncRNA in DFS to further clarify the role of DFS in the prognosis of patients in UCEC.

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PMC11774251

To further elucidate the mechanism of Tan-I in treating psoriasis, we performed RNA-seq on lesional skin.

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PMC10551595

Effect of GinA on (A) CCRF‐CEM and RCCRF‐CEM T‐ALL cell, (B) NALM6 and RN95 B‐ALL cell lines, in addition to (C) normal mononuclear cells.

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PMC11711871

In our study, the assessment of the aortic vasoreactivity revealed changes in the response of vascular rings to phenylephrine and DEA/NO, but not to KCl and acetylcholine, although Emax and EC50 were not significantly different between groups and diet conditions.

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PMC11317131

PBS, trypsin, and Opti-MEM were purchased from Gibco.

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PMC10033453

This could have slowed viral replication down to tip the balance in favor of cancer cell replication.

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PMC9817179

The fixation artifact of an LLPS system can be represented as the absolute change in punctate percentage, or the ratio of in-puncta POI to total POI, after fixation:(1)ΔPunctate Percentage=Final Punctate Percentage−Initial Punctate Percentage=([S3 ]t=∞[S3 ]t=∞+[S4 ]t=∞−[S1 ]t=0[S1 ]t=0+[S2 ]t=0)∗100 (A) Schematic that ...

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PMC9429973

We cross-referenced differentially expressed (DE) metabolites with DE genes (3’ RNAseq) in a matched set of samples to identify important biological pathways.

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PMC9429973

Relapse occurred in 25.7% of the patients, 31.9% in the group w/IO and 20.7% w/o IO (p=0.26).

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PMC11763126

E IP assay confirmed that CBDP1 can bind to YTHDF2.

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PMC11640247

Notably, RAC3 is integral to several key aspects of neuronal development, including neurite extension, axonal and dendritic formation, synaptogenesis, and neuronal migration .

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PMC11661040

MG63 and 143B cells were seeded in 6-well plates, and the cells were transfected with 20 nM siRNAs using Lipofectamine 2000 reagent according to the manufacturer’s instructions.

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PMC9325715

The maximum of the corresponding band shifted from 1391 to 1385 cm after iron incorporation.

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PMC11495567

These results support the potential use of the PCAIs as targeted therapies against cancers with KRAS mutations.

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PMC7987994

Three triplicates were used for each sample.

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PMC11643491

Although the mean of the AR is highest for the stretch ratio 1.4–1.7, there is a large distribution in the AR of those particles (Figure 1C).

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PMC9429973

Median follow-up (patients alive) was 70.2 (46.3-83.5) months.

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PMC9429973

When TN pts with ASXL1 were considered apart, having a ratio <1.31 retained its inferior prognostic impact compared to the ratio ≥1.31 group (median OS 57 vs 104 months, p<0.0453; HR 1.8 [1-3.2]), with TN/ASXL1 pts being associated with the worst outcome (median OS 24 months) (Fig.1C).

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PMC9031474

In this review, we will focus on bicyclic drimane and coloratane sesquiterpenoids.

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PMC6799808

Caspase-dependent and caspase-independent apoptosis can be induced under different conditions.

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PMC9429973

Aims: QuANTUM-First aimed to determine if the addition of Quiz to standard induction (IND) and post remission (including allogeneic hematopoietic cell transplant [allo-HCT]) in first complete remission [CR1]) consolidation followed by single-agent continuation therapy for up to 3 years improved survival compared with c...

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PMC11718109

Scale bar, 500 nm.

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PMC11653533

Ficus serves as a reservoir for numerous phytochemicals, showcasing a rich diversity of bioactive compounds within its structure (Fig. 4, Fig. 5).

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PMC11769516

They are mainly related to the increase in oxidative stress in neuronal cells, which leads to higher levels of pro-inflammatory cytokines as IL-1β, IL-6 and TNF-α, enzymatic activity as GST, GPx, CAT and SOD and neurotransmitter dysfunction (5-HT, serotonin, dopamine and GABA).

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PMC11387401

Three ASOs per target gene were designed with the LNCASO online webtool (sequences in Appendix Table S8).

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PMC11337594

Fig. 1TER inhibits cell viability and induces apoptosis in melanoma cells. (

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PMC11473843

Relative cell number of HBEC3-FAK KO cell line transduced as in (D); n = 3. (

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PMC11730311

For estimation of half-lives, experimental units are denoted as n = 1 and correspond to a single mouse IV dosed with compound.

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PMC5941560

Note that these query descriptions are abbreviations of more detailed search terms, which are provided in the “Methods” section Jurkat publication trends.

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PMC8009078

The hydrogen bonds formed by each ligand with TMPRSS2 in each frame were calculated and it is given in Fig. 8.

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PMC11704135

in a dark environment.

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PMC11345828

The resultant product was N-methylated using General Procedure D followed by saponification following General Procedure G (30 mg, 64% yield over 2 steps).

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PMC4839679

Renal cell carcinoma (RCC) is the most common (~80%) and lethal type of kidney cancer in adults with clear cell RCC (ccRCC) as the most prevalent and aggressive subtype .

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PMC11489351

Normal epithelial cells have an intracellular pH (pHi) of ∼7.2, but transient changes in pHi (6.8–7.6) have been shown to regulate cell behaviors, including cell migration (1), proliferation (2, 3), and differentiation (4) (Fig. 1A).

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PMC10291556

Recently, it has been shown both in vitro and in vivo that in contrast to cisplatin, oxaliplatin and its analogues induce immunogenic cell death (ICD) and thereby synergistically potentiate antitumor effects.

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PMC11397654

IC50 was found to be 12.95 μM for 33a and 16.13 μM for 33b against the DLD-1 cell line.

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PMC10747160

SARS-CoV-2 Wuhan nCov-19 strain (NCBI Reference Sequence: NC_045512.2) spike pseudotyped lentiviral virions were produced as previously described .

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PMC11240571

Specifically, it has been reported that RT activates host immunity induced by immunogenic cell death , induces IFN-γ that leaves dendritic cells, and stimulates innate immunity associated with IFN pathway activity , as well as inducing chemokines and adhesion factors involved in T cell migration and infiltration .

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PMC11653168

The present findings may pave the way for further clinical investigations into Stattic and emphasize the importance of targeting dysregulated STAT3 signaling in leukemia therapy.

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PMC11200978

When the combination of gemcitabine pretreatment and a single −15 °C freeze was applied, a significant increase in the necrotic cell population with a corresponding decrease in live cells was observed.

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PMC10812665

They arrest their cell cycle, express biochemical markers of dopaminergic neurons, and develop a neurite network .

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PMC9429973

Aims: To investigate the pathophysiological basis of iron overload in PKD.

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PMC11615218

TCR repertoire can be used as a surrogate for the T-cell clonotype and expansion .

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PMC10530622

RNAi is a natural process that involves the suppression of gene expression using small interfering RNA (siRNA).

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PMC9429973

Patient NK cells demonstrated decreased levels of KIRs (CD158a and CD158b) compared to HC (16.2±5 vs 33.8±2.1; p<0.01 and 17.6±6 vs 32.4±3.1; p<0.01, respectively), despite being exclusively CD56, and as such expected to highly express KIRs.

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PMC11279598

Manuka honey (MH) is a monofloral honey that is produced from the nectar collected by honey bees (Apis Mellifera) when they pollinate the Manuka tea tree (Leptospermum scoparium).

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PMC11758416

Addition of concanamycin A reduced the level of L cell death in TCR-stimulated CD8 T cell conditions, but not in unstimulated conditions (Figure 3E).

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PMC11033180

Whether Sema5A-induced synapsin 1 clustering in enteric neurons is achieved through regulation of O-glycosylation or homo- and heterodimerization of synapsin 1 remains to be studied.

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PMC9429973

Many patients lose response over time, highlighting an unmet need for novel therapies.

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PMC9895440

24 h later, NY-ESO-1 TCR lentiviral particles produced as described above were added at a multiplicity of infection (MOI) of 2.

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PMC11055510

Compared with the si-nc group, the cell healing rate in the si-circMAN1A2 group was significantly reduced (Fig. 2G).

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