OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11531735	Subsequently, the polymerase chain reaction (PCR) was employed to identify and isolate the female offspring exhibiting the desired transgenic profile.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Subsequ...
PMC10158546	Taken together, while differentiated ReN cells expressed markers of neurons and astrocytes, in our hands they did not fully mature into neurons that express markers of synaptic signalling.	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10999934	As an important organelle for protein processing, the endoplasmic reticulum is essential to maintain physiological activities.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "an", "important", "organelle", "for", ...
PMC11786600	The orange dashed vertical line indicates the boundary of the wound epidermis; the red dashed line denotes the limit of the granulation tissue; the yellow arrow outlines the granulation tissue thickness; the purple dashed line represents the epidermal margin; the black arrow highlights neovascularization and the green ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11306331	n = 51,42,31,35,31,23 cells from conditions labeled left to right, pooled from three biological replicates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "n", "=", "51,42,31,35,31,23", "cells", "from", "condit...
PMC10419319	To determine the effect of isoalantolactone on the proliferation of cisplatin-sensitive and resistant OC cells, OC cells were exposed to different concentrations of isoalantolactone for 24 h. Isoalantolactone was more cytotoxic against A2780 and SNU-8 than A2780 and SNU-8 cells, respectively (Figure 1B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11380454	This finding suggests that the compound probably has relatively selective primary activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "finding", "suggests", "that", "the", "compound", "probably", "has", "rel...
PMC11380454	Moreover, while PD-L1 expression was dose-dependently inhibited by SAS or AS101 in B16/F10 cells (Fig. 4B), AML cells (Fig. 4G) or A549 cells (Fig. S3B) transfected with a control plasmid, this inhibition was abrogated when Akt was overexpressed (Fig. 4C, F and Fig. S3C) (see transfections in Fig. S1A, C and F).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11721587	Here, we provide evidence that nuclear Ci/Gli may exist in a complex containing phosphorylated Ci/Gli, mature Fu/Ulk3, and Sufu (Fig. 8).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11593031	The complex karyotype of Neuro-2a includes mitotically stable dicentres, neocentrics, and complex rearrangements resembling chromothripsis events.	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "complex", "karyotype", "of",...
PMC9429973	One patient (45 µg) reported a grade 2 infusion related reaction (IRR) that lasted less than 12 hours following the first administration only.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11001582	g, LFP power in the slow-wave frequency band (left panel), mid gamma-frequency band (center panel) and high gamma-frequency band (right panel) in WT, (GR)400 and (PR)400 mice at 15–19 months of age.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11709639	Initially, we examined MCUB expression in AD patient samples, AD model mice, and AD cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Initially", ",", "we", "examined"...
PMC11774112	The surface morphology of the Co-PHRD samples was then visualized by transmission electron microscopy (TEM) (H600, Hitachi, Tokyo, Japan).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10317042	The standard treatment for CCS involves surgical resection with an adequate margin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "standard", "treatment", "for", "CCS", "involves", "surgical", "resection", ...
PMC9429973	Summary/Conclusion: We present the 5th and 6th patient with germline hemizygous deleterious variants in SASH3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Summary/Conclusion", ":", "We", "present", "the", "5th...
PMC10218459	The results showed that the treatment of the RD-ES cell line with CPP combined with DOX and VIN significantly increased the antiproliferative effect.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	At a median follow up of 9.4 months (range 3.1–10.0), the overall response rate was 72.7% (8 pts; VGPR: 27.3% [3 pts] and partial response: 45.5% [5 pts]).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10698968	Data obtained from 2D tests show that MF-R 3 cells have similar sensitivity to that of 143B cell line for both drugs (Fig. 5A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC11412721	Strikingly, when we compared the survival of 30% patients with the highest ACKR4 mRNA levels to the survival of the 30% patients with the lowest ACKR4 mRNA levels, high ACKR4 expression correlated with a better prognosis in men, but not in women (Figure 4C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11774112	The results showed that DTIC encapsulated in micelles had a certain sustained release effect, which provided a basis for increasing the stability of drugs and prolonging their action time.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9503541	Approximately 25% of clinically used drugs are derived from plants, with more than 60% of these drugs having anticancer activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Approxi...
PMC9429973	E. Koster, C. Halkes, E. Bogers, C. Hazenberg, F. Heubel-Moenen, S. Langemeier, E. Meijer, E. Nur, M. Raaijmakers, T. Snijders, M. de Witte, J. Tjon, L. de Wreede Hematology, Leiden University Center, Leiden; Hematology, University Medical Center Groningen, Groningen; Hematology, Maastricht University Medical Center, M...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9581083	M. officinalis is an important TCM herb for the treatment of a wide variety of conditions, including gastrointestinal disorders, typhoid fever, thrombotic stroke, allergies, anxiety, and nervous disturbances.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11267830	a RNA-seq analysis of the types and numbers of alternative splicing events that occur after indisulam treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "a", "RNA-seq", "analysis", "of", "the", "ty...
PMC5673060	Pazopanib and dasatinib resistant A204 cell lines (PazR & DasR respectively) were generated and heavy SILAC labelled as previously described .	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Pazopanib...
PMC11706776	Among them, calcium-activated potassium channels (KCa) are divided into three subclasses, namely small conductance (SKCa: SK1, SK2, and SK3), intermediate conductance, and big conductance, based on their unitary conductance .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11655498	EBV is almost impossible to be cleared from the host due to its effective latency and periodic reactivation that is initiated by appropriate signals.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11707577	was able to deeply penetrate the spheroid core and break up, upon irradiation, its supracellular structure.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "was", "able", "to", "deeply", "penetra...
PMC11461833	HEK293 wild-type (WT) cells was transfected with the empty vector pCAG-3HA were used as the control group (Ctrl OE).	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens"...
PMC9847912	In keeping with the results observed in spreading infections of CEMss cells, GSK232 was highly active against HIV-1 isolates Q23-17, NL4-3, MJ4, and 94UG114.1.6 in the single cycle assay (S3 Fig).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11757131	Studies have shown that 3-HIB promotes autophagy by upregulating the expression of autophagy-related genes (35), thereby providing the energy and materials necessary for cell proliferation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11476666	Resveratrol (RSV) is a naturally occurring compound belonging to the stilbene family, which has gained extensive attention in recent years because of its potential health benefits .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9368503	NIH-3T3 was used as a mouse positive control and SK-UT-1 was used as a human positive control.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "NIH-3T3", "was", "used", "as", ...
PMC9776316	Targeting the JNK-cJUN-XRCC4 would presumably hold the potential clinical translation of overcoming cisplatin resistance in ovarian cancer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Targeting", "the", "JNK-cJUN-XRCC4", "would", "pr...
PMC10899471	Besides, miR-939-3p was identified as a potential independent prognostic marker in lung cancer (39).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Besides", ",", "miR-939", "-", ...
PMC10743717	It is the main hub of exercise-upregulated mitochondrial proteins and is involved in a variety of metabolic pathways including neurosteroid metabolism to regulate allopregnanolone homeostasis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11320834	Data are shown as the mean ± SD, n = 3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "shown", "as", "the", "mean", "±", "SD", ",", "n", "="...
PMC11695546	Findings with p < 0.05 were referred to substantial change.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Findings", "with", "p", "<", "0.05", "were", "referred", "to", "substantial", "change", "....
PMC10582049	We found that the expression of ADH1B positively correlates with ADH1B CAF enrichment score (Fig. 4D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "found", "that", "the", "expressi...
PMC9398137	Patient-derived lymphoma xenografts (PDX) were established in our laboratory from patients with treatment-refractory DLBCL, Burkitt lymphoma, or Richter syndrome as described previously (19, 20).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10538569	Importantly, anti-HA PacBlue labeled GPI-scFv X5 is detected on the surface of DiD labeled iDCs, but not GFP, which is internally expressed in transduced CEMss cells, indicating that scFvs when anchored to GPI can be transferred from T cells to iDCs in co-culture ( Figure 8C ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11380329	Human OVCAR4 cells were incubated for 48 h. with the IC50s of P from different geographical origin either alone or co-supplemented with vitamin D using the results obtained from Drug Reduction Indices analysis which were briefly as follow: 38.7045 μg/mL for Egy P + 0.01480 μg/mL for Vit D, 47.4519 μg/mL for Ger P + 0.0...	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11422150	The results confirm that hAMSC treatment produced an anti-inflammatory and neuroprotective effect at the SCI site.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "results", "confirm", "that", "hAMSC", "treatmen...
PMC3122064	Treatment of cisplatin-sensitive Tera and 833KE cells and cisplatin-resistant Tera-CP, Scha, and 2102EP cells, all expressing wild-type p53, with Nutlin-3 resulted in a dose-dependent reduction in cell survival.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11534377	Images of the scratch area were taken at regular intervals until the gap was closed in at least one experimental condition, with all images captured at 100× magnification.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11746948	We next examined the impact of GPX4 palmitoylation on protein stability using GPX4-C66S and GPX4-C75S mutants.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "next", "examined", "the", "impact", "of", ...
PMC9739791	Both mixtures under low-dose light irradiation (460 nm, 0.36 J/cm) demonstrated higher cytotoxicity than in the dark.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Both", "mixtures", "under", ...
PMC8978939	Fibronectin mRNA expression of 786-O, WT, P138R, and L163R cell lines.	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fibronectin", "mRNA", "expression", "of", "786-O", ",", "WT",...
PMC9429973	It is a highly aggressive disease characterized by skin and bone marrow involvement and is associated with a poor prognosis (median overall survival 8–14 months).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11412721	Asynchronous MEFs were exposed to 0–10 Gy γ-irradiation, and after 24 hr, cells were labeled with BrdU for 1 hr and analyzed by FACS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11790971	Furthermore, through violin plots and statistical analysis, we observed that the majority of top-ranking features are informative to differentiate a subset of cell lines instead of all four cell lines (Fig. 5b).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11609529	At 72 h post-transduction, equal numbers of cells from each transduced group were set up to culture for an additional 72 h and were then analyzed for cell proliferation, apoptosis, and cell cycle.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11297139	We next sought to identify the mechanism by which ARID1A LLPS affects oncogenic potential in Ewing’s sarcoma cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "next", "sought", ...
PMC11489351	Briefly, 450 μl of room temperature serum-free media were added to a 0.6 ml Eppendorf tube, and 10 μg of DNA was then added to the Eppendorf tube and mixed by inverting the tube 4 to 5 times.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11694066	CCL5 (F) and CXCL10 (G) mRNA were analyzed separately relative to RPLP0.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CCL5", "(", "F", ")", "and", "CXCL10", "(", ...
PMC11802929	Doublets were removed.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "Doublets", "were", "removed", "." ] } ]
PMC9424261	We found that HERPUD1 reduces MDM2 ubiquitination in liver cancer cells (Fig. 5G), while MDM2 induces the ubiquitination of GSS, thereby reducing the content of GSS, and finally inhibiting the synthesis of GSH to increase ferroptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6461034	All evidence lines are integrated in a kinase‐specific INKA score using the geometric mean of combined spectral count data (“C”) for kinase‐centric and substrate‐centric modalities.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11509309	MovS6 is a murine peripheral neuroglial cell line expressing the ovine PrP protein under the control of its endogenous gene promoter.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MovS6", "is", ...
PMC11653533	Still, in contrast, both leaves extracted by water with cellulase complex appeared to have the least antioxidant action (Bertoletti et al., 2018).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9910796	Transfected polyprotein pp220 assembles into electron-dense coats (blue arrowheads) under the PM or surrounding cytoplasmic endosome (End) and lysosomes. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC7342409	Analysis of variance (ANOVA) and statistical tests were analyzed means of multiple groups in the GraphPad Prism statistical software.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Analysis", "of", ...
PMC11411004	5CHO-ADM cells treated with DMSO or 2 μM I-4 and Western blotting to detect changes in the protein expression levels of HDAC substrates a Ac-H3K9 and Ac-H3K27 and LSD1 substrate b H3K4me2 and total histone H3, LSD1 proteins.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The frequency of alleles was 25.54%.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "frequency", "of", "alleles", "was", "25.54", "%", "." ] } ]
PMC11482552	If the HPV test result is positive, the patient is then referred for cytological testing.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "If", "the", "HPV", "test", "result", "is", "posi...
PMC11783017	Schematic image of the co-culture system of 143B cells with RAW264.7 and DCs (created by Figdraw).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Schematic", "image", "of", ...
PMC5963610	Figure 5A indicates the experimental scheme for the case of NK1.1 cell depletion.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Figure", "5A", "indicates", "the", "experimental", "scheme", "for", "the", ...
PMC11409031	There exist four distinguishable varieties of M2 macrophages: M2a, M2b, M2c, and M2d.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "exist", "four", "distinguishable", "vari...
PMC10808409	The EE % was calculated using Eq. (1):1[12pt] $$}\% = }/} 00$$%=weight of the drug in micelles/weight of the drug used in the preparation of micelles×100 The micelles’ particle size and the polydispersity index (PDI) were measured for all the prepared formulae by dynamic light scattering technique, using zetasizer (Mal...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	At baseline cITP patients experienced meaningful QoL impairment by all SF-36 scales excluding pain as compared to healthy controls (p<0.05).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "baseli...
PMC8875242	This is consistent with evidence that ABCB1-mediated digoxin transport appears to be affected by a wide spectrum of clinically relevant compounds .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "is", "con...
PMC9429973	W. Liu, O. Stencel, Z. Lu, C. Xu, P. Lang, F. Auer, J. Hauer, U. Fischer, A. Borkhardt, A. Pandyra Department of Molecular Medicine II; Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich-Heine University, Düsseldorf; Department of Pediatrics, Technical University of Munich, Munich, Germany B...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11774747	These studies are summarized in Tables 1 , 2 .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "studies", "are", "summarized", "in", "Tables", "1", ",", "2", "." ] } ]
PMC11658074	Scale bars = 5 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bars", "=", "5", "μm", "." ] } ]
PMC9429973	T. Abuasab, J. Senapati, T. Kadia, F. Ravandi, C. DiNardo, N. Pemmaraju, M. Ohanion, Y. Alvarado, H. Kantarjian, G. Borthakur Department of Leukemia, The University of Texas, MD Anderson Cancer Center, Houston, TX, USA, Houston, United States of America Background: Core-binding factor acute myeloid leukemia (CBF-AML), ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11659921	Further screening of the six genes included in the prognostic model, alongside clinical factors, is planned.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Further", "screening", "of", "the", "s...
PMC5810978	Furthermore, no HuNoV and HuSaV RNA titer changes were detected in human small intestine cDNA-transfected Vero and Caco-2 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O" ], "tokens": [ "Furthermore", ",...
PMC10033453	Mouse body weight and clinical observations were also recorded three times per week.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mouse", "body", "weight", "and", "clinical", "observations", "were", "also"...
PMC10024132	Thus, our approach may have the potential for application to treatment of solid tumors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", "our", "approach", "may", "have", "the", ...
PMC9429973	Image: Summary/Conclusion: This study showed a short duration of RUX therapy for real-world patients with MF, and poorer clinical status at FEDR initiation than at RUX initiation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11696659	Other authors declare no potential conflicts of interest.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Other", "authors", "declare", "no", "potential", "conflicts", "of", "interest", "." ] } ]
PMC9532503	A decrease in fucosylation at Asn297 (asparagine) has been shown to increase the antibody-binding affinity to CD16 (FcγRIIIa) on natural killer cells and ultimately increase ADCC potency .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10530622	These results were validated in a second mouse model of NAFLD, in which a mouse received a Western-type diet.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "results", "were", ...
PMC9429973	RNAseq analyses indicated de-regulation of migratory pathway that was functionally confirmed by migration experiments with the specific chemokines (i.e. CCL19, CCL21 and SDF1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11757131	Data are shown as mean ± standard error of mean; means not sharing the same letter are different (p < 0.05).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11461874	This is probably because catalytically inactive TRAF7 continues to interact with DBP without the ubiquitination process.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "is", "probably", "because", "catalytically", "...
PMC8728081	As the HTXRD of Kajjali was conducted on the open surface (on a glass plate in XRD instrument), it is inferred that Kajjali did not transform to Rasasindura up to 325 °C (Fig. 1e); and only above 350 °C, Kajjali started to evaporate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11754094	Target sequences were designed using Cas-Designer to avoid off-target sequences (up to 2 mismatches).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Target", "sequences", "were", "designed", "using", "Ca...
PMC11535726	The comparison of the nucleotides between the sequences of K.longirostrata (GZCC 23-0733) and K.crustacea (MFLU 21-0129) shows differences of 8.4% (39/467 bp) across ITS and 0.7% (5/718 bp) across LSU, excluding gaps.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11790599	Notably, neither liproxstatin-1 (Lip-1, a ferroptosis inhibitor) nor necrostatin-1 (Nec-1, a necroptosis inhibitor) could prevent cell death induced by TSL in SK-BR-3 and ZR-75-1 cells (Supplementary Figures S4B–C), ruling out these cell death modes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11706491	Alternatively, the use of a Neubauer chamber provides snapshots at various culture times but fails to differentiate between live and dead cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Alterna...
PMC11754094	P = 0.0386 for CBE, P = 0.0059 for CBE (ΔUGI), P = 0.0046 for CGBE1, P = 0.0006 for ABE, P = 0.0163 for ABE-UGI and P < 0.0001 for AYBE compared to nCas9 (D10A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10213179	The KD indicated that ATOP had high affinity for A673 cells, with a value in the nanomolar range (Figure 4B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11643361	The bis-pyrazol-1-yl conjugate 31 showed lower cytotoxicity than the standalone NMDA antagonist, while the second derivative, 32, not only matched but, in some assays, surpassed the antagonist’s activity—particularly against T24 and Caki2 cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11283030	In general, cancer cells can attenuate anti-tumor immune response by competing for essential nutrients and reducing the metabolic fitness of TIICs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "genera...
PMC7823217	Unsurprisingly, a study investigating angiogenesis within MCTS of undifferentiated melanoma cell line, NA8-MCTS, revealed that the invasion and network formation of HMEC-1 cell line within NA8-MCTS increased following co-culturing with HMEC-1 .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "...
PMC3164356	The absence of CP77 causes a rapid shutdown of viral protein synthesis machinery.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "absence", "of", "CP77", "causes", "a", "rapid", "shutdown", "o...
PMC11656657	T-test was applied for the analysis. *	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "T-test", "was", "applied", "for", "the", "analysis", ".", "*" ] } ]
PMC11683240	The bar graph (E) shows the quantifications of Western blot signals from seven independent experiments, while (F and G) show blots of representative experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11531735

Subsequently, the polymerase chain reaction (PCR) was employed to identify and isolate the female offspring exhibiting the desired transgenic profile.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Subsequ...

PMC10158546

Taken together, while differentiated ReN cells expressed markers of neurons and astrocytes, in our hands they did not fully mature into neurons that express markers of synaptic signalling.

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PMC10999934

As an important organelle for protein processing, the endoplasmic reticulum is essential to maintain physiological activities.

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PMC11786600

The orange dashed vertical line indicates the boundary of the wound epidermis; the red dashed line denotes the limit of the granulation tissue; the yellow arrow outlines the granulation tissue thickness; the purple dashed line represents the epidermal margin; the black arrow highlights neovascularization and the green ...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11306331

n = 51,42,31,35,31,23 cells from conditions labeled left to right, pooled from three biological replicates.

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PMC10419319

To determine the effect of isoalantolactone on the proliferation of cisplatin-sensitive and resistant OC cells, OC cells were exposed to different concentrations of isoalantolactone for 24 h. Isoalantolactone was more cytotoxic against A2780 and SNU-8 than A2780 and SNU-8 cells, respectively (Figure 1B).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11380454

This finding suggests that the compound probably has relatively selective primary activity.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "finding", "suggests", "that", "the", "compound", "probably", "has", "rel...

PMC11380454

Moreover, while PD-L1 expression was dose-dependently inhibited by SAS or AS101 in B16/F10 cells (Fig. 4B), AML cells (Fig. 4G) or A549 cells (Fig. S3B) transfected with a control plasmid, this inhibition was abrogated when Akt was overexpressed (Fig. 4C, F and Fig. S3C) (see transfections in Fig. S1A, C and F).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11721587

Here, we provide evidence that nuclear Ci/Gli may exist in a complex containing phosphorylated Ci/Gli, mature Fu/Ulk3, and Sufu (Fig. 8).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC11593031

The complex karyotype of Neuro-2a includes mitotically stable dicentres, neocentrics, and complex rearrangements resembling chromothripsis events.

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PMC9429973

One patient (45 µg) reported a grade 2 infusion related reaction (IRR) that lasted less than 12 hours following the first administration only.

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PMC11001582

g, LFP power in the slow-wave frequency band (left panel), mid gamma-frequency band (center panel) and high gamma-frequency band (right panel) in WT, (GR)400 and (PR)400 mice at 15–19 months of age.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11709639

Initially, we examined MCUB expression in AD patient samples, AD model mice, and AD cell lines.

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PMC11774112

The surface morphology of the Co-PHRD samples was then visualized by transmission electron microscopy (TEM) (H600, Hitachi, Tokyo, Japan).

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PMC10317042

The standard treatment for CCS involves surgical resection with an adequate margin.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "standard", "treatment", "for", "CCS", "involves", "surgical", "resection", ...

PMC9429973

Summary/Conclusion: We present the 5th and 6th patient with germline hemizygous deleterious variants in SASH3.

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PMC10218459

The results showed that the treatment of the RD-ES cell line with CPP combined with DOX and VIN significantly increased the antiproliferative effect.

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PMC9429973

At a median follow up of 9.4 months (range 3.1–10.0), the overall response rate was 72.7% (8 pts; VGPR: 27.3% [3 pts] and partial response: 45.5% [5 pts]).

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PMC10698968

Data obtained from 2D tests show that MF-R 3 cells have similar sensitivity to that of 143B cell line for both drugs (Fig. 5A).

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PMC11412721

Strikingly, when we compared the survival of 30% patients with the highest ACKR4 mRNA levels to the survival of the 30% patients with the lowest ACKR4 mRNA levels, high ACKR4 expression correlated with a better prognosis in men, but not in women (Figure 4C).

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PMC11774112

The results showed that DTIC encapsulated in micelles had a certain sustained release effect, which provided a basis for increasing the stability of drugs and prolonging their action time.

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PMC9503541

Approximately 25% of clinically used drugs are derived from plants, with more than 60% of these drugs having anticancer activity.

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PMC9429973

E. Koster, C. Halkes, E. Bogers, C. Hazenberg, F. Heubel-Moenen, S. Langemeier, E. Meijer, E. Nur, M. Raaijmakers, T. Snijders, M. de Witte, J. Tjon, L. de Wreede Hematology, Leiden University Center, Leiden; Hematology, University Medical Center Groningen, Groningen; Hematology, Maastricht University Medical Center, M...

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PMC9581083

M. officinalis is an important TCM herb for the treatment of a wide variety of conditions, including gastrointestinal disorders, typhoid fever, thrombotic stroke, allergies, anxiety, and nervous disturbances.

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PMC11267830

a RNA-seq analysis of the types and numbers of alternative splicing events that occur after indisulam treatment.

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PMC5673060

Pazopanib and dasatinib resistant A204 cell lines (PazR & DasR respectively) were generated and heavy SILAC labelled as previously described .

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PMC11706776

Among them, calcium-activated potassium channels (KCa) are divided into three subclasses, namely small conductance (SKCa: SK1, SK2, and SK3), intermediate conductance, and big conductance, based on their unitary conductance .

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PMC11655498

EBV is almost impossible to be cleared from the host due to its effective latency and periodic reactivation that is initiated by appropriate signals.

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PMC11707577

was able to deeply penetrate the spheroid core and break up, upon irradiation, its supracellular structure.

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PMC11461833

HEK293 wild-type (WT) cells was transfected with the empty vector pCAG-3HA were used as the control group (Ctrl OE).

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PMC9847912

In keeping with the results observed in spreading infections of CEMss cells, GSK232 was highly active against HIV-1 isolates Q23-17, NL4-3, MJ4, and 94UG114.1.6 in the single cycle assay (S3 Fig).

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PMC11757131

Studies have shown that 3-HIB promotes autophagy by upregulating the expression of autophagy-related genes (35), thereby providing the energy and materials necessary for cell proliferation.

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PMC11476666

Resveratrol (RSV) is a naturally occurring compound belonging to the stilbene family, which has gained extensive attention in recent years because of its potential health benefits .

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PMC9368503

NIH-3T3 was used as a mouse positive control and SK-UT-1 was used as a human positive control.

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PMC9776316

Targeting the JNK-cJUN-XRCC4 would presumably hold the potential clinical translation of overcoming cisplatin resistance in ovarian cancer.

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PMC10899471

Besides, miR-939-3p was identified as a potential independent prognostic marker in lung cancer (39).

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PMC10743717

It is the main hub of exercise-upregulated mitochondrial proteins and is involved in a variety of metabolic pathways including neurosteroid metabolism to regulate allopregnanolone homeostasis.

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PMC11320834

Data are shown as the mean ± SD, n = 3.

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PMC11695546

Findings with p < 0.05 were referred to substantial change.

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PMC10582049

We found that the expression of ADH1B positively correlates with ADH1B CAF enrichment score (Fig. 4D).

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PMC9398137

Patient-derived lymphoma xenografts (PDX) were established in our laboratory from patients with treatment-refractory DLBCL, Burkitt lymphoma, or Richter syndrome as described previously (19, 20).

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PMC10538569

Importantly, anti-HA PacBlue labeled GPI-scFv X5 is detected on the surface of DiD labeled iDCs, but not GFP, which is internally expressed in transduced CEMss cells, indicating that scFvs when anchored to GPI can be transferred from T cells to iDCs in co-culture ( Figure 8C ).

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PMC11380329

Human OVCAR4 cells were incubated for 48 h. with the IC50s of P from different geographical origin either alone or co-supplemented with vitamin D using the results obtained from Drug Reduction Indices analysis which were briefly as follow: 38.7045 μg/mL for Egy P + 0.01480 μg/mL for Vit D, 47.4519 μg/mL for Ger P + 0.0...

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PMC11422150

The results confirm that hAMSC treatment produced an anti-inflammatory and neuroprotective effect at the SCI site.

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PMC3122064

Treatment of cisplatin-sensitive Tera and 833KE cells and cisplatin-resistant Tera-CP, Scha, and 2102EP cells, all expressing wild-type p53, with Nutlin-3 resulted in a dose-dependent reduction in cell survival.

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PMC11534377

Images of the scratch area were taken at regular intervals until the gap was closed in at least one experimental condition, with all images captured at 100× magnification.

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PMC11746948

We next examined the impact of GPX4 palmitoylation on protein stability using GPX4-C66S and GPX4-C75S mutants.

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PMC9739791

Both mixtures under low-dose light irradiation (460 nm, 0.36 J/cm) demonstrated higher cytotoxicity than in the dark.

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PMC8978939

Fibronectin mRNA expression of 786-O, WT, P138R, and L163R cell lines.

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PMC9429973

It is a highly aggressive disease characterized by skin and bone marrow involvement and is associated with a poor prognosis (median overall survival 8–14 months).

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PMC11412721

Asynchronous MEFs were exposed to 0–10 Gy γ-irradiation, and after 24 hr, cells were labeled with BrdU for 1 hr and analyzed by FACS.

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PMC11790971

Furthermore, through violin plots and statistical analysis, we observed that the majority of top-ranking features are informative to differentiate a subset of cell lines instead of all four cell lines (Fig. 5b).

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PMC11609529

At 72 h post-transduction, equal numbers of cells from each transduced group were set up to culture for an additional 72 h and were then analyzed for cell proliferation, apoptosis, and cell cycle.

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PMC11297139

We next sought to identify the mechanism by which ARID1A LLPS affects oncogenic potential in Ewing’s sarcoma cell lines.

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PMC11489351

Briefly, 450 μl of room temperature serum-free media were added to a 0.6 ml Eppendorf tube, and 10 μg of DNA was then added to the Eppendorf tube and mixed by inverting the tube 4 to 5 times.

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PMC11694066

CCL5 (F) and CXCL10 (G) mRNA were analyzed separately relative to RPLP0.

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PMC11802929

Doublets were removed.

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PMC9424261

We found that HERPUD1 reduces MDM2 ubiquitination in liver cancer cells (Fig. 5G), while MDM2 induces the ubiquitination of GSS, thereby reducing the content of GSS, and finally inhibiting the synthesis of GSH to increase ferroptosis.

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PMC6461034

All evidence lines are integrated in a kinase‐specific INKA score using the geometric mean of combined spectral count data (“C”) for kinase‐centric and substrate‐centric modalities.

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PMC11509309

MovS6 is a murine peripheral neuroglial cell line expressing the ovine PrP protein under the control of its endogenous gene promoter.

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PMC11653533

Still, in contrast, both leaves extracted by water with cellulase complex appeared to have the least antioxidant action (Bertoletti et al., 2018).

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PMC9910796

Transfected polyprotein pp220 assembles into electron-dense coats (blue arrowheads) under the PM or surrounding cytoplasmic endosome (End) and lysosomes. (

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PMC7342409

Analysis of variance (ANOVA) and statistical tests were analyzed means of multiple groups in the GraphPad Prism statistical software.

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PMC11411004

5CHO-ADM cells treated with DMSO or 2 μM I-4 and Western blotting to detect changes in the protein expression levels of HDAC substrates a Ac-H3K9 and Ac-H3K27 and LSD1 substrate b H3K4me2 and total histone H3, LSD1 proteins.

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PMC9429973

The frequency of alleles was 25.54%.

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PMC11482552

If the HPV test result is positive, the patient is then referred for cytological testing.

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PMC11783017

Schematic image of the co-culture system of 143B cells with RAW264.7 and DCs (created by Figdraw).

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PMC5963610

Figure 5A indicates the experimental scheme for the case of NK1.1 cell depletion.

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PMC11409031

There exist four distinguishable varieties of M2 macrophages: M2a, M2b, M2c, and M2d.

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PMC10808409

The EE % was calculated using Eq. (1):1[12pt] $$}\% = }/} 00$$%=weight of the drug in micelles/weight of the drug used in the preparation of micelles×100 The micelles’ particle size and the polydispersity index (PDI) were measured for all the prepared formulae by dynamic light scattering technique, using zetasizer (Mal...

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PMC9429973

At baseline cITP patients experienced meaningful QoL impairment by all SF-36 scales excluding pain as compared to healthy controls (p<0.05).

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PMC8875242

This is consistent with evidence that ABCB1-mediated digoxin transport appears to be affected by a wide spectrum of clinically relevant compounds .

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PMC9429973

W. Liu, O. Stencel, Z. Lu, C. Xu, P. Lang, F. Auer, J. Hauer, U. Fischer, A. Borkhardt, A. Pandyra Department of Molecular Medicine II; Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich-Heine University, Düsseldorf; Department of Pediatrics, Technical University of Munich, Munich, Germany B...

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PMC11774747

These studies are summarized in Tables 1 , 2 .

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PMC11658074

Scale bars = 5 μm.

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PMC9429973

T. Abuasab, J. Senapati, T. Kadia, F. Ravandi, C. DiNardo, N. Pemmaraju, M. Ohanion, Y. Alvarado, H. Kantarjian, G. Borthakur Department of Leukemia, The University of Texas, MD Anderson Cancer Center, Houston, TX, USA, Houston, United States of America Background: Core-binding factor acute myeloid leukemia (CBF-AML), ...

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PMC11659921

Further screening of the six genes included in the prognostic model, alongside clinical factors, is planned.

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PMC5810978

Furthermore, no HuNoV and HuSaV RNA titer changes were detected in human small intestine cDNA-transfected Vero and Caco-2 cells.

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PMC10033453

Mouse body weight and clinical observations were also recorded three times per week.

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PMC10024132

Thus, our approach may have the potential for application to treatment of solid tumors.

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PMC9429973

Image: Summary/Conclusion: This study showed a short duration of RUX therapy for real-world patients with MF, and poorer clinical status at FEDR initiation than at RUX initiation.

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PMC11696659

Other authors declare no potential conflicts of interest.

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PMC9532503

A decrease in fucosylation at Asn297 (asparagine) has been shown to increase the antibody-binding affinity to CD16 (FcγRIIIa) on natural killer cells and ultimately increase ADCC potency .

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PMC10530622

These results were validated in a second mouse model of NAFLD, in which a mouse received a Western-type diet.

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PMC9429973

RNAseq analyses indicated de-regulation of migratory pathway that was functionally confirmed by migration experiments with the specific chemokines (i.e. CCL19, CCL21 and SDF1).

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PMC11757131

Data are shown as mean ± standard error of mean; means not sharing the same letter are different (p < 0.05).

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PMC11461874

This is probably because catalytically inactive TRAF7 continues to interact with DBP without the ubiquitination process.

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PMC8728081

As the HTXRD of Kajjali was conducted on the open surface (on a glass plate in XRD instrument), it is inferred that Kajjali did not transform to Rasasindura up to 325 °C (Fig. 1e); and only above 350 °C, Kajjali started to evaporate.

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PMC11754094

Target sequences were designed using Cas-Designer to avoid off-target sequences (up to 2 mismatches).

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PMC11535726

The comparison of the nucleotides between the sequences of K.longirostrata (GZCC 23-0733) and K.crustacea (MFLU 21-0129) shows differences of 8.4% (39/467 bp) across ITS and 0.7% (5/718 bp) across LSU, excluding gaps.

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PMC11790599

Notably, neither liproxstatin-1 (Lip-1, a ferroptosis inhibitor) nor necrostatin-1 (Nec-1, a necroptosis inhibitor) could prevent cell death induced by TSL in SK-BR-3 and ZR-75-1 cells (Supplementary Figures S4B–C), ruling out these cell death modes.

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PMC11706491

Alternatively, the use of a Neubauer chamber provides snapshots at various culture times but fails to differentiate between live and dead cells.

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PMC11754094

P = 0.0386 for CBE, P = 0.0059 for CBE (ΔUGI), P = 0.0046 for CGBE1, P = 0.0006 for ABE, P = 0.0163 for ABE-UGI and P < 0.0001 for AYBE compared to nCas9 (D10A).

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PMC10213179

The KD indicated that ATOP had high affinity for A673 cells, with a value in the nanomolar range (Figure 4B).

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PMC11643361

The bis-pyrazol-1-yl conjugate 31 showed lower cytotoxicity than the standalone NMDA antagonist, while the second derivative, 32, not only matched but, in some assays, surpassed the antagonist’s activity—particularly against T24 and Caki2 cell lines.

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PMC11283030

In general, cancer cells can attenuate anti-tumor immune response by competing for essential nutrients and reducing the metabolic fitness of TIICs.

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PMC7823217

Unsurprisingly, a study investigating angiogenesis within MCTS of undifferentiated melanoma cell line, NA8-MCTS, revealed that the invasion and network formation of HMEC-1 cell line within NA8-MCTS increased following co-culturing with HMEC-1 .

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PMC3164356

The absence of CP77 causes a rapid shutdown of viral protein synthesis machinery.

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PMC11656657

T-test was applied for the analysis. *

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PMC11683240

The bar graph (E) shows the quantifications of Western blot signals from seven independent experiments, while (F and G) show blots of representative experiments.

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