OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11286266	This is partly mediated by direct heterodimerisation of N-ATF6α with XBP1s, the active, spliced form (Yamamoto et al., 2007; Yamamoto et al., 2004).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11734514	Wound healing assay and IL-6/VEGF mRNA expression in A549 cells treated with C. aerizusa. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Wound", "healing", "assay", "and", "IL-6/VEGF", "mRNA", ...
PMC11607764	Among these, PTBP1, as a pan-cancer-related RBP, is highly expressed in a range of solid and hematological tumors and is significantly associated with poor prognosis, making it a highly valuable potential biomarker for further research.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11802929	Antigens were then assigned by the maximally mapped dextramer for each cell.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Antigens", "were", "then", "assigned", "by", "the", "maximally", "mapped", "dext...
PMC8633974	This approach was used to evaluate RT activity and cell vitality in infected control (untreated) and treated groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "approach", "was", ...
PMC10142392	Among the three star-shaped copolymers (3s/4s/6s-PLGA-PEG), DOX-loaded S-PLGA-PEG micelles with four arms showed the highest cellular uptake and cytotoxicity, possibly due to the difference in size and distribution of PEG on the surface of S-PLGA-PEG micelles.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11618052	0.53 (hexane : ethyl acetate, 1 : 2, v/v).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "0.53", "(", "hexane", ":", "ethyl", "acetate", ",", "1", ":", "...
PMC11656657	Tumor growth did not significantly differ across the aforementioned cell models.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tumor", "growth", "did", "not", "significantly", "differ", "across", "the", "aforementioned...
PMC11533140	Compounds 17e, 17m, 17o, and 17p exhibited strong inhibitory activity against PI3Kα, and 17e, 17o, and 17p also showed strong antiproliferative activity against four cancer cell lines (A2780, U87MG, MCF7, and DU145), all comparable to or better than those of BKM-120.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11627133	To enable straightforward and widely applicable protein imaging by SMLM, we sought to leverage the capabilities of RhoBAST to protein‐binding aptamers by creating bifunctional aptamers (Figure 1A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6934009	Furthermore, the treatment led to a marked increase in the activation of caspase 3/8/9 and the generation of reactive oxygen species (ROS) at 72 h in A427 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5941560	While both the original 1977 publication and the American Type Culture Collection (ATCC) report that Jurkat is diploid, other publications refute this description.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11627133	N=3 for dSTORM, N=4 for RhoBAST‐PAINT).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "N=3", "for", "dSTORM", ",", "N=4", "for", "RhoBAST‐PAINT", ")", "." ] } ]
PMC11635519	Each 50 μL reaction mixture contained 3.2 μg of template, 2× PCR buffer, 2× enhancer solution, 300 μM each dNTP, 900 nM each for Adapter A (5′-AATGATACGGCGACCACCGAAATGGACTATCATATGCTTACCGTAACTTGAA-3′), and Adapter B (5′-CAAGCAGAA-GACGGCATACGATGTGGATGAATACTGCCATTTGTCTCGAGGTC-3′), 1 mM MgSO4, 3.75 units of Platinum Pfx po...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11628904	However, treatment with isotonic saline showed no evidence of wound expansion that would indicate burn wound conversion and instead exhibited a slight decrease in wound depth.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8336407	Table 3) Lipids are the most susceptible biological molecules to the attack of ROS and RNS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Table", "3", ")", "Lipids", "are", "the", ...
PMC11678130	The cell viability was calculated according to the following formula: (1)Cell Viability (%)=Absorbance of treated cellsAbsorbance of Control × 100 The IC50 value was calculated using the GraphPad software (version 10.4.1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10362265	Altogether, PDB structures of hIL18 structures underscore the importance of the short surface epitope of IL18 between 68 and 81 for controlling its activity by affecting the heterodimer conformation/stability and self-assembly.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11348300	Results are displayed in SI Appendix, Fig. S1 where the distribution and localization of PpIX PF and HS signal can be visually compared for both i.v.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10938336	The proportion of HL-60 cells in early and late apoptosis was determined after a 24 h treatment.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "proportion", "of", "HL-60", "cell...
PMC11696576	Screening of compound activities in 66 cancer cell lines was carried out at the Netherlands Translation Research Center.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Screening", "of", "compound", "activities", ...
PMC11334037	P < 0.05; P < 0.01; P < 0.001.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P", "<", "0.05", ";", "P", "<", "0.01", ";", "P", "<", "0.001", "." ]...
PMC11087766	Since the PhiKZ PicA Q297K mutant shows reduced trafficking of gp104 into the phage nucleus, we also tested whether this mutant shows a decrease in accumulation of this stalled gp104 chimera.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10988555	Nonetheless, and despite these important advances in ruthenium complexes, these compounds still present some toxicity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Nonetheless", ",", "and", "despite", "these", ...
PMC9429973	A phase 2, randomized, double-blind, placebo-controlled trial of siltuximab for the treatment of iMCD (NCT01024036) showed that 18/53 patients (34%) responded to treatment, compared with 0% in the placebo group, but it is not known how long patients should be maintained on siltuximab before deciding whether the treatme...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Clonality was not available testing in any pts.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Clonality", "was", "not", "available", "testing", "in", "any", "pts", "." ] } ]
PMC11723210	These include mouse vascular endothelial cells (C166 cells) for slide-based imaging, human cervical cancer cells (HeLa cells) for QPI validation, and African green monkey kidney fibroblast cells (COS-7 cells) for live-cell culture studies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "...
PMC11348300	The reason why PRESTO appears as a compelling methodology lies in the intrinsic hypoxic nature of solid tumors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "reason", "why", "PRESTO", "appe...
PMC11365983	Accordingly, we established a clonal NIH3T3 cell line stably expressing Gli2-mGFP, and first demonstrated that it recapitulated the SAG-dependent accumulation of Gli1 protein observed in NIH3T3 cells (Fig. 4A,B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4277423	Having demonstrated that co-transducing CEMss-CCR5 with two individual lentiviral vectors expressing Cas9 and CR2 efficiently disrupt CCR5 gene, we next constructed a single lentiviral transfer vector expressing both CR2 and Cas9 along with EGFP reporter gene (Fig. 7A).	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11033180	Cells were then plated (day 0) either in Ibidi 24-well plates (cat: 82426, ibidi, Gräfelfing, Germany) for FM1-43 imaging or in 24-well plastic culture plates for Western blot analyses.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8557138	Moreover, bioprinting offers the possibility of controlling the alignment of cells, as well as to strategically modulate cellular signaling pathways; thus recapitulating the specific microstructure of target tissue or organ compared to standard tissue fabrication approaches (Chakraborty and Ghosh 2020).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9164404	A Differential lipids between PBS and Abplatin treated cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "Differential", "lipids", "between", "PBS", "and", "Abplatin", "treated", "cells", "." ] } ]
PMC11534035	After the incubation period, SM was removed and replaced with OptiMEM (31985-047, Gibco, Thermo Fischer Scientific, Rochester, NY, USA) on the adherent cells in the culture flask.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11461833	Scale bars, 50m. (K) Protein expression was analyse via western blotting with an anti-Lamin B1 antibody.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bars", ",", "...
PMC10706275	Conversely, cell lines with random integration events exhibited co-expression of both the EGFP and mCherry genes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Conversely", ",", "cell", "lines", "with", ...
PMC6600253	In the absence apoptosis, stressors could also drive cells into senescence through RAS, and this mechanism works as a barrier to block tumor growth in vivo .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11789597	CyTOF software 6.7 (Standard BioTools) was used to normalize and debarcode the data.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CyTOF", "software", "6.7", "(", "Standard", "BioTools", ")"...
PMC10669128	Thus, it is clear that not only the cell of origin but also the tumor microenvironment plays a crucial role in determining the final tumor phenotype .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11464982	The Panel identified a no observed adverse effect level of 1010 mg TOS/kg bw per day, the highest dose tested, which when compared with the estimated dietary exposure, resulted in a margin of exposure of at least 168,333.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11599565	To determine the molecular basis of the morphological conversion of epithelial cancer cells into neuron-like cells under the genotoxic stress of cisplatin, we first conducted a gene expression analysis focusing on markers indicative of neuronal conversion.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11343332	Following a 24-hour exposure to a pyrogenol sample (80 µg/ml), the nuclear appearance of apoptotic cells is investigated using AO/EtBr dual-labeling.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10578720	Upper: western blots analysis with β-actin as a loading control.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Upper", ":", "western", "blots", "analysis", "with", "β-actin", "as", "a", "loading",...
PMC11337594	Heatmap showing the differences in the expression of key enzymes involved in amino sugar and nucleotide sugar metabolism in control and TER-treated A375 cells. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ],...
PMC8735881	Fusion genes encoding the single-chain variable fragment (scFv) of 3BNC117, N6, PGT126, PGT128, 10E8, or 35O22 were constructed with a self-inactivating lentiviral vector, and they were efficiently expressed in the lipid raft sites of target cell membrane without affecting the expression of HIV-1 receptors (CD4, CCR5 a...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10092581	During the past decade, the synthesis and evaluation of several Au(I)‐ and Ag(I)‐NHC complexes were pursued with much interest due to their wide range of pharmacological properties.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10870498	Anaplastic thyroid cancer (ATC) is the most malignant thyroid cancer .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Anaplastic", "thyroid", "cancer", "(", "ATC", ")", "is", "the", "most", "m...
PMC11711663	Additionally, the significant association between certain radiomics features and progression-free survival suggests that imaging features might reflect some underlying molecular characteristics of the tumors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC8711270	Compared to HEK, CHO cells are not able to completely reproduce human glycostructures.	[ { "tags": [ "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Compared", "to", "HEK", ",", "CHO", "cells", "are", ...
PMC11342785	The GFP and Fluor 594 intensities were determined using Fiji.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "GFP", "and", "Fluor", "594", "intensities", "were", "determined", "using", "Fiji", ...
PMC7433824	YWHAZ also involved in controlling the mRNA stability by AU‐rich element‐binding proteins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "YWHAZ", "also", "involved", "in", "controlling", "the", "mRNA", "stability", "by...
PMC10944868	438.2 mg, 46%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "438.2", "mg", ",", "46", "%", ")", "." ] } ]
PMC6114978	Samples utilized for quantiative Western blot were run in triplicate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Samples", "utilized", "for", "quantiative", "Western", "blot", "were", "run", "in", "triplicate"...
PMC2193049	The rapid cleavage of the fusion protein by Ub-specific proteases after the last residue of Ub yields equimolar amounts of the protein of interest and the reference protein bearing a COOH-terminal Ub moiety.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10761571	In brief, 0.2 mL of MTT solution was added to the wells and incubated for 4h.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "brief", ",", "0.2", "mL", "of", ...
PMC11049294	The quenching of exofacial Fl-Gb3 was obtained with addition of 0.4% trypan blue before sample measurement.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "quenching", "of", "exofacial", "Fl-Gb3", ...
PMC11766309	The results demonstrated that YKT6 had the greatest positive correlations with the immune scores in BLCA, LAML, LGG, and UVM (Figure 7A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11745823	However, there was no research yet has focused on the role of RIT1 in the development of glioma.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "there", "was", ...
PMC11422150	Afterward, the samples were subjected to electrophoresis, fluoresced, and photographed, and the signal intensity was measured using ImageJ. RNA expression levels of the untreated SCI group on Day 7 were used as the control.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11741906	The changes were considered when the fold change values were greater than or equal to 2 or less than 0.5.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "changes", "were", ...
PMC11021472	CircZDHHC11 expression levels in the miR-150BSdel monoclonal cell line were similar to the levels observed in unmodified cells and in a monoclonal cell line infected with 2 non-targeting sgRNAs (NTCR1CR2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10055960	Cisplatin and carboplatin were tested in parallel in the same concentration range for both ligands (1, 2), dirhodium complexes (3–6), and metallodendrimers (8–10).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10452486	The expression of HLA-F was first observed on the surface of B lymphocyte and monocyte cell lines and in vivo on extravillous trophoblasts that had invaded the maternal decidua .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11092418	However, no EGFR inhibitor has yet been approved for the treatment of patients with brain cancer, indicating that targeting EGFR alone may not be sufficient in some patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10421378	Pour plate counts were performed in MRS agar and incubated under anaerobic conditions at 37 °C for 48 h. Imaging flow cytometry is a type of flow cytometry that combines the high-throughput analysis capabilities of flow cytometry with the imaging capabilities of microscopy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11725127	Coomassie brilliant blue-stained SDS-PAGE gel of precipitates pulled down by biotin–GA, 90 kDa, and 70 kDa, which were then identified by mass spectrometry to be HSP90 and USP2, respectively. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9143157	In Figure 2A–C, we firstly analyzed the intracellular uptake of THP and P-THP in MES-SA, MEA-SA C9, and MEA-SA C9 high cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "I-CellLine", "O", "O", "B-CellLine", ...
PMC9429973	The most common adverse events in all subjects (n=16) were headache (38%), self-limited rash (25%), and abdominal pain (19%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11707832	MAN2B1 plays a pivotal role in the breakdown of N-linked glycan chains released during the intracellular metabolism of glycoproteins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MAN2B1", "plays", "a", "pivotal",...
PMC6742971	Control experiment with the Melan-A negative melanoma cell line Na8, with and without the addition of synthetic Melan-A peptide (“EAA”; EAAGIGILTV) at the concentration of 1 μM, showing results that are representative for two experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9878562	On the other side it has been proposed that ACKR3 can form heterodimers on the plasma membrane with CXCR4 altering its activity (8, 59).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10728535	For example, Ng et al. (2014) observed that the TMEM98 gene played a critical role in the emergence and development of chemotherapy‐resistance in hepatocellular carcinoma through activating AKT signaling pathway and deactivating p53.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10671321	He was first examined in 2001 in Turkey where the variant in COLQ was first identified by Sanger sequencing (Figure 1A right panel).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC5810978	The NoV RNA level increase (28-fold increase) in the 1-month cultured Caco-2 cells at 9 dpi was similar to that (36-fold increase) of the primary inoculation on the 1-month cultured Caco-2 cells, whereas that in the 2-month cultured Caco-2 cells showed a 424-fold increase at 9 dpi.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10728200	Protein-protein interactions in GIST-T1 and 882 cells were validated by a CO-IP assay using an anti-STUB1 and an anti-GPX4 antibody.	[ { "tags": [ "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Protein-prote...
PMC11502443	At the WT GIP receptor, both endogenous agonists GIP(1-42) and GIP(1-30)NH2, and tirzepatide stimulated a concentration-dependent increase in signaling for all pathways measures (Figures 1A–E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11200978	In vivo, additional stressors including ischemia and nutrient deprivation due to vascular disruption and activation of an immune response, among others, would likely result in increased cell death .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7961460	MDA-MB-231 cells express lower levels of c10orf118 but are more aggressive than MCF-7, which express higher amounts of c10orf118.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MDA-MB-231", "ce...
PMC11412752	Severe hepatic involvement with an acute hepatitis-like clinical appearance has been reported as a possible consequence of Salmonella infection .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Severe", "hepatic", "involvement", ...
PMC9672323	The effect of three different concentrations of dexamethasone (a) and piroxicam (b) was assessed on the proliferation of T cells in PBMCs (n = 3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11725127	To test this hypothesis, A ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) hydrolytic assay was performed as previously described.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "test", "this", "hypothesis", ",", "A"...
PMC11240052	The experiment was carried out according to the Life Technologies Apoptosis Assay protocol, and the samples were analyzed by flow cytometry within 1 h using a FACS Caliber (Becton Dickinson, CA) in triplicate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	All measurements were performed in bone marrow samples or in peripheral blood at initial diagnosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "measurements", "were", "performed", "in", "bone", "m...
PMC10387886	Serous ovarian carcinoma is the most frequent histological subtype of ovarian carcinoma .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Serous", "ovarian", "carcinoma", "is", "the", "most", "frequent", "histological", ...
PMC9596868	CI values were calculated according to the classic isobologram equation (see materials and methods).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CI", "values", "were", "calculated", "according", "to"...
PMC7189327	The DEGs between BCC and normal controls were screened according to the threshold of the multiple comparison correction false discovery rate (FDR) < 0.05.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10988555	After 24 h incubation, at the same conditions as described previously, the medium was replaced by medium with DMSO 0.1% (v/v), 0.4 μM DOX, a 5 μM cisplatin or IC50 of the complexes 2–4, and incubated for 48 h. After that, cells were detached using cold PBS 1× and a cell scraper and centrifuged at 500 × g for 5 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9812014	6-O-Butanoylcastanospermine (B-CAST) is a castanospermine alkaloid that was evaluated for its anti-MLV activities in chronically infected C3HlOTY1/2 (clone 8) cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11279397	Eugenol has antiviral properties against IAV and HSV , inhibiting viral replication.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Eugenol", "has", "antiviral", "properties", "against", "IAV", "and", "HSV", ",",...
PMC11001582	Eggs were placed at a standard density into bottles containing SYA medium.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Eggs", "were", "placed", "at", "a", "standard", "density", "into", "bottles", ...
PMC9429973	Given the increased expression of MYC following DYRK1A inhibition we performed a new Western blot analysis and validated increased expression of BIM in our KMT2A-R ALL cell lines after EHT1610 treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", ...
PMC11682224	Band intensities were analyzed using Image J software.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Band", "intensities", "were", "analyzed", "using", "Image", "J", "software", "." ] } ]
PMC11694066	I, Model of EWS–WT1–driven DSRCT sensitivity to PARPi and ATRi. *,	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "I", ",", "Model", "of", "EWS", "–", "WT1–driven", "DS...
PMC11155445	The large number of H⋯H, O⋯H and S⋯H intermolecular interactions were responsible for the crystal packing of molecules (Fig. 3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC11773391	Our experimental findings suggest that TMZ promotes the transcription of MGMT by activating the ERK signalling pathway and that the use of an ERK pathway inhibitor effectively increases the sensitivity of melanoma cell lines to TMZ both in vivo and in vitro by downregulating MGMT levels.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4485786	Together, these data show that the transplanted mice developed a human T-cell immune system that closely resembled the human in vivo situation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Togethe...
PMC10538569	Transduced or untransduced CD4 cells were plated in triplicate on a 96 well U-bottom plate (VWR).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Transduced", "or", "untransduced", "CD4", ...
PMC11594641	Non-reducing Laemmli buffer was used for the analysis of the CD63 or CD81 proteins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Non-reducing", "Laemmli", "buffer", "was", "used", "for", "the", ...
PMC9545474	FITC annexin‐V apoptosis assay: Flow cytometry analysis of apoptotic populations was carried out using the FITC Annexin V Apoptosis Detection Kit with PI (BioLegend®) according to manufacturer's instructions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11676169	These results render an interaction between these proteins feasible.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "results", "render", "an", "interaction", "between", "these", "proteins", "feasible", "." ] }...

PMC11286266

This is partly mediated by direct heterodimerisation of N-ATF6α with XBP1s, the active, spliced form (Yamamoto et al., 2007; Yamamoto et al., 2004).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11734514

Wound healing assay and IL-6/VEGF mRNA expression in A549 cells treated with C. aerizusa. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Wound", "healing", "assay", "and", "IL-6/VEGF", "mRNA", ...

PMC11607764

Among these, PTBP1, as a pan-cancer-related RBP, is highly expressed in a range of solid and hematological tumors and is significantly associated with poor prognosis, making it a highly valuable potential biomarker for further research.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11802929

Antigens were then assigned by the maximally mapped dextramer for each cell.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Antigens", "were", "then", "assigned", "by", "the", "maximally", "mapped", "dext...

PMC8633974

This approach was used to evaluate RT activity and cell vitality in infected control (untreated) and treated groups.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "approach", "was", ...

PMC10142392

Among the three star-shaped copolymers (3s/4s/6s-PLGA-PEG), DOX-loaded S-PLGA-PEG micelles with four arms showed the highest cellular uptake and cytotoxicity, possibly due to the difference in size and distribution of PEG on the surface of S-PLGA-PEG micelles.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11618052

0.53 (hexane : ethyl acetate, 1 : 2, v/v).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "0.53", "(", "hexane", ":", "ethyl", "acetate", ",", "1", ":", "...

PMC11656657

Tumor growth did not significantly differ across the aforementioned cell models.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tumor", "growth", "did", "not", "significantly", "differ", "across", "the", "aforementioned...

PMC11533140

Compounds 17e, 17m, 17o, and 17p exhibited strong inhibitory activity against PI3Kα, and 17e, 17o, and 17p also showed strong antiproliferative activity against four cancer cell lines (A2780, U87MG, MCF7, and DU145), all comparable to or better than those of BKM-120.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11627133

To enable straightforward and widely applicable protein imaging by SMLM, we sought to leverage the capabilities of RhoBAST to protein‐binding aptamers by creating bifunctional aptamers (Figure 1A).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC6934009

Furthermore, the treatment led to a marked increase in the activation of caspase 3/8/9 and the generation of reactive oxygen species (ROS) at 72 h in A427 cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC5941560

While both the original 1977 publication and the American Type Culture Collection (ATCC) report that Jurkat is diploid, other publications refute this description.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11627133

N=3 for dSTORM, N=4 for RhoBAST‐PAINT).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "N=3", "for", "dSTORM", ",", "N=4", "for", "RhoBAST‐PAINT", ")", "." ] } ]

PMC11635519

Each 50 μL reaction mixture contained 3.2 μg of template, 2× PCR buffer, 2× enhancer solution, 300 μM each dNTP, 900 nM each for Adapter A (5′-AATGATACGGCGACCACCGAAATGGACTATCATATGCTTACCGTAACTTGAA-3′), and Adapter B (5′-CAAGCAGAA-GACGGCATACGATGTGGATGAATACTGCCATTTGTCTCGAGGTC-3′), 1 mM MgSO4, 3.75 units of Platinum Pfx po...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11628904

However, treatment with isotonic saline showed no evidence of wound expansion that would indicate burn wound conversion and instead exhibited a slight decrease in wound depth.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8336407

Table 3) Lipids are the most susceptible biological molecules to the attack of ROS and RNS.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Table", "3", ")", "Lipids", "are", "the", ...

PMC11678130

The cell viability was calculated according to the following formula: (1)Cell Viability (%)=Absorbance of treated cellsAbsorbance of Control × 100 The IC50 value was calculated using the GraphPad software (version 10.4.1).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10362265

Altogether, PDB structures of hIL18 structures underscore the importance of the short surface epitope of IL18 between 68 and 81 for controlling its activity by affecting the heterodimer conformation/stability and self-assembly.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11348300

Results are displayed in SI Appendix, Fig. S1 where the distribution and localization of PpIX PF and HS signal can be visually compared for both i.v.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10938336

The proportion of HL-60 cells in early and late apoptosis was determined after a 24 h treatment.

[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "proportion", "of", "HL-60", "cell...

PMC11696576

Screening of compound activities in 66 cancer cell lines was carried out at the Netherlands Translation Research Center.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Screening", "of", "compound", "activities", ...

PMC11334037

P < 0.05; P < 0.01; P < 0.001.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P", "<", "0.05", ";", "P", "<", "0.01", ";", "P", "<", "0.001", "." ]...

PMC11087766

Since the PhiKZ PicA Q297K mutant shows reduced trafficking of gp104 into the phage nucleus, we also tested whether this mutant shows a decrease in accumulation of this stalled gp104 chimera.

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PMC10988555

Nonetheless, and despite these important advances in ruthenium complexes, these compounds still present some toxicity.

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PMC9429973

A phase 2, randomized, double-blind, placebo-controlled trial of siltuximab for the treatment of iMCD (NCT01024036) showed that 18/53 patients (34%) responded to treatment, compared with 0% in the placebo group, but it is not known how long patients should be maintained on siltuximab before deciding whether the treatme...

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PMC9429973

Clonality was not available testing in any pts.

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PMC11723210

These include mouse vascular endothelial cells (C166 cells) for slide-based imaging, human cervical cancer cells (HeLa cells) for QPI validation, and African green monkey kidney fibroblast cells (COS-7 cells) for live-cell culture studies.

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PMC11348300

The reason why PRESTO appears as a compelling methodology lies in the intrinsic hypoxic nature of solid tumors.

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PMC11365983

Accordingly, we established a clonal NIH3T3 cell line stably expressing Gli2-mGFP, and first demonstrated that it recapitulated the SAG-dependent accumulation of Gli1 protein observed in NIH3T3 cells (Fig. 4A,B).

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PMC4277423

Having demonstrated that co-transducing CEMss-CCR5 with two individual lentiviral vectors expressing Cas9 and CR2 efficiently disrupt CCR5 gene, we next constructed a single lentiviral transfer vector expressing both CR2 and Cas9 along with EGFP reporter gene (Fig. 7A).

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PMC11033180

Cells were then plated (day 0) either in Ibidi 24-well plates (cat: 82426, ibidi, Gräfelfing, Germany) for FM1-43 imaging or in 24-well plastic culture plates for Western blot analyses.

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PMC8557138

Moreover, bioprinting offers the possibility of controlling the alignment of cells, as well as to strategically modulate cellular signaling pathways; thus recapitulating the specific microstructure of target tissue or organ compared to standard tissue fabrication approaches (Chakraborty and Ghosh 2020).

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PMC9164404

A Differential lipids between PBS and Abplatin treated cells.

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PMC11534035

After the incubation period, SM was removed and replaced with OptiMEM (31985-047, Gibco, Thermo Fischer Scientific, Rochester, NY, USA) on the adherent cells in the culture flask.

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PMC11461833

Scale bars, 50m. (K) Protein expression was analyse via western blotting with an anti-Lamin B1 antibody.

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PMC10706275

Conversely, cell lines with random integration events exhibited co-expression of both the EGFP and mCherry genes.

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PMC6600253

In the absence apoptosis, stressors could also drive cells into senescence through RAS, and this mechanism works as a barrier to block tumor growth in vivo .

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PMC11789597

CyTOF software 6.7 (Standard BioTools) was used to normalize and debarcode the data.

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PMC10669128

Thus, it is clear that not only the cell of origin but also the tumor microenvironment plays a crucial role in determining the final tumor phenotype .

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PMC11464982

The Panel identified a no observed adverse effect level of 1010 mg TOS/kg bw per day, the highest dose tested, which when compared with the estimated dietary exposure, resulted in a margin of exposure of at least 168,333.

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PMC11599565

To determine the molecular basis of the morphological conversion of epithelial cancer cells into neuron-like cells under the genotoxic stress of cisplatin, we first conducted a gene expression analysis focusing on markers indicative of neuronal conversion.

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PMC11343332

Following a 24-hour exposure to a pyrogenol sample (80 µg/ml), the nuclear appearance of apoptotic cells is investigated using AO/EtBr dual-labeling.

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PMC10578720

Upper: western blots analysis with β-actin as a loading control.

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PMC11337594

Heatmap showing the differences in the expression of key enzymes involved in amino sugar and nucleotide sugar metabolism in control and TER-treated A375 cells. (

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PMC8735881

Fusion genes encoding the single-chain variable fragment (scFv) of 3BNC117, N6, PGT126, PGT128, 10E8, or 35O22 were constructed with a self-inactivating lentiviral vector, and they were efficiently expressed in the lipid raft sites of target cell membrane without affecting the expression of HIV-1 receptors (CD4, CCR5 a...

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PMC10092581

During the past decade, the synthesis and evaluation of several Au(I)‐ and Ag(I)‐NHC complexes were pursued with much interest due to their wide range of pharmacological properties.

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PMC10870498

Anaplastic thyroid cancer (ATC) is the most malignant thyroid cancer .

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PMC11711663

Additionally, the significant association between certain radiomics features and progression-free survival suggests that imaging features might reflect some underlying molecular characteristics of the tumors.

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PMC8711270

Compared to HEK, CHO cells are not able to completely reproduce human glycostructures.

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PMC11342785

The GFP and Fluor 594 intensities were determined using Fiji.

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PMC7433824

YWHAZ also involved in controlling the mRNA stability by AU‐rich element‐binding proteins.

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PMC10944868

438.2 mg, 46%).

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PMC6114978

Samples utilized for quantiative Western blot were run in triplicate.

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PMC2193049

The rapid cleavage of the fusion protein by Ub-specific proteases after the last residue of Ub yields equimolar amounts of the protein of interest and the reference protein bearing a COOH-terminal Ub moiety.

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PMC10761571

In brief, 0.2 mL of MTT solution was added to the wells and incubated for 4h.

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PMC11049294

The quenching of exofacial Fl-Gb3 was obtained with addition of 0.4% trypan blue before sample measurement.

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PMC11766309

The results demonstrated that YKT6 had the greatest positive correlations with the immune scores in BLCA, LAML, LGG, and UVM (Figure 7A).

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PMC11745823

However, there was no research yet has focused on the role of RIT1 in the development of glioma.

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PMC11422150

Afterward, the samples were subjected to electrophoresis, fluoresced, and photographed, and the signal intensity was measured using ImageJ. RNA expression levels of the untreated SCI group on Day 7 were used as the control.

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PMC11741906

The changes were considered when the fold change values were greater than or equal to 2 or less than 0.5.

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PMC11021472

CircZDHHC11 expression levels in the miR-150BSdel monoclonal cell line were similar to the levels observed in unmodified cells and in a monoclonal cell line infected with 2 non-targeting sgRNAs (NTCR1CR2).

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PMC10055960

Cisplatin and carboplatin were tested in parallel in the same concentration range for both ligands (1, 2), dirhodium complexes (3–6), and metallodendrimers (8–10).

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PMC10452486

The expression of HLA-F was first observed on the surface of B lymphocyte and monocyte cell lines and in vivo on extravillous trophoblasts that had invaded the maternal decidua .

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PMC11092418

However, no EGFR inhibitor has yet been approved for the treatment of patients with brain cancer, indicating that targeting EGFR alone may not be sufficient in some patients.

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PMC10421378

Pour plate counts were performed in MRS agar and incubated under anaerobic conditions at 37 °C for 48 h. Imaging flow cytometry is a type of flow cytometry that combines the high-throughput analysis capabilities of flow cytometry with the imaging capabilities of microscopy.

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PMC11725127

Coomassie brilliant blue-stained SDS-PAGE gel of precipitates pulled down by biotin–GA, 90 kDa, and 70 kDa, which were then identified by mass spectrometry to be HSP90 and USP2, respectively. (

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PMC9143157

In Figure 2A–C, we firstly analyzed the intracellular uptake of THP and P-THP in MES-SA, MEA-SA C9, and MEA-SA C9 high cells.

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PMC9429973

The most common adverse events in all subjects (n=16) were headache (38%), self-limited rash (25%), and abdominal pain (19%).

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PMC11707832

MAN2B1 plays a pivotal role in the breakdown of N-linked glycan chains released during the intracellular metabolism of glycoproteins.

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PMC6742971

Control experiment with the Melan-A negative melanoma cell line Na8, with and without the addition of synthetic Melan-A peptide (“EAA”; EAAGIGILTV) at the concentration of 1 μM, showing results that are representative for two experiments.

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PMC9878562

On the other side it has been proposed that ACKR3 can form heterodimers on the plasma membrane with CXCR4 altering its activity (8, 59).

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PMC10728535

For example, Ng et al. (2014) observed that the TMEM98 gene played a critical role in the emergence and development of chemotherapy‐resistance in hepatocellular carcinoma through activating AKT signaling pathway and deactivating p53.

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PMC10671321

He was first examined in 2001 in Turkey where the variant in COLQ was first identified by Sanger sequencing (Figure 1A right panel).

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PMC5810978

The NoV RNA level increase (28-fold increase) in the 1-month cultured Caco-2 cells at 9 dpi was similar to that (36-fold increase) of the primary inoculation on the 1-month cultured Caco-2 cells, whereas that in the 2-month cultured Caco-2 cells showed a 424-fold increase at 9 dpi.

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PMC10728200

Protein-protein interactions in GIST-T1 and 882 cells were validated by a CO-IP assay using an anti-STUB1 and an anti-GPX4 antibody.

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PMC11502443

At the WT GIP receptor, both endogenous agonists GIP(1-42) and GIP(1-30)NH2, and tirzepatide stimulated a concentration-dependent increase in signaling for all pathways measures (Figures 1A–E).

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PMC11200978

In vivo, additional stressors including ischemia and nutrient deprivation due to vascular disruption and activation of an immune response, among others, would likely result in increased cell death .

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PMC7961460

MDA-MB-231 cells express lower levels of c10orf118 but are more aggressive than MCF-7, which express higher amounts of c10orf118.

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PMC11412752

Severe hepatic involvement with an acute hepatitis-like clinical appearance has been reported as a possible consequence of Salmonella infection .

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PMC9672323

The effect of three different concentrations of dexamethasone (a) and piroxicam (b) was assessed on the proliferation of T cells in PBMCs (n = 3).

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PMC11725127

To test this hypothesis, A ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) hydrolytic assay was performed as previously described.

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PMC11240052

The experiment was carried out according to the Life Technologies Apoptosis Assay protocol, and the samples were analyzed by flow cytometry within 1 h using a FACS Caliber (Becton Dickinson, CA) in triplicate.

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PMC9429973

All measurements were performed in bone marrow samples or in peripheral blood at initial diagnosis.

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PMC10387886

Serous ovarian carcinoma is the most frequent histological subtype of ovarian carcinoma .

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PMC9596868

CI values were calculated according to the classic isobologram equation (see materials and methods).

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PMC7189327

The DEGs between BCC and normal controls were screened according to the threshold of the multiple comparison correction false discovery rate (FDR) < 0.05.

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PMC10988555

After 24 h incubation, at the same conditions as described previously, the medium was replaced by medium with DMSO 0.1% (v/v), 0.4 μM DOX, a 5 μM cisplatin or IC50 of the complexes 2–4, and incubated for 48 h. After that, cells were detached using cold PBS 1× and a cell scraper and centrifuged at 500 × g for 5 min.

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PMC9812014

6-O-Butanoylcastanospermine (B-CAST) is a castanospermine alkaloid that was evaluated for its anti-MLV activities in chronically infected C3HlOTY1/2 (clone 8) cells.

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PMC11279397

Eugenol has antiviral properties against IAV and HSV , inhibiting viral replication.

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PMC11001582

Eggs were placed at a standard density into bottles containing SYA medium.

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PMC9429973

Given the increased expression of MYC following DYRK1A inhibition we performed a new Western blot analysis and validated increased expression of BIM in our KMT2A-R ALL cell lines after EHT1610 treatment.

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PMC11682224

Band intensities were analyzed using Image J software.

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PMC11694066

I, Model of EWS–WT1–driven DSRCT sensitivity to PARPi and ATRi. *,

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PMC11155445

The large number of H⋯H, O⋯H and S⋯H intermolecular interactions were responsible for the crystal packing of molecules (Fig. 3).

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PMC11773391

Our experimental findings suggest that TMZ promotes the transcription of MGMT by activating the ERK signalling pathway and that the use of an ERK pathway inhibitor effectively increases the sensitivity of melanoma cell lines to TMZ both in vivo and in vitro by downregulating MGMT levels.

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PMC4485786

Together, these data show that the transplanted mice developed a human T-cell immune system that closely resembled the human in vivo situation.

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PMC10538569

Transduced or untransduced CD4 cells were plated in triplicate on a 96 well U-bottom plate (VWR).

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PMC11594641

Non-reducing Laemmli buffer was used for the analysis of the CD63 or CD81 proteins.

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PMC9545474

FITC annexin‐V apoptosis assay: Flow cytometry analysis of apoptotic populations was carried out using the FITC Annexin V Apoptosis Detection Kit with PI (BioLegend®) according to manufacturer's instructions.

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PMC11676169

These results render an interaction between these proteins feasible.

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