OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11574029	Consistent with the in vitro results, the inhibitory effects of targeting NOTCH3 on tumor growth and metastasis were counteracted by SPP1 overexpression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Consist...
PMC9429973	Therefore, automated LIC measurements using artificial intelligence (AI) or deep-learning-assessed (DLA) algorithms could provide the solution for globally affordable and reliable patient monitoring of LIC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11519567	Data are mean±s.d.,	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "mean±s.d", ".", "," ] } ]
PMC9429973	In addition, gut microbiota plays a key role in the efficacy and toxicity of antitumor treatments, especially immunotherapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", ...
PMC11389534	UFM1 is initially synthesised as a precursor molecule, proUFM1, which then undergoes processing by UFM1‐specific protease 1 (UFSP1) and UFM1‐specific protease 2 (UFSP2), , , , , resulting in a mature UFM1 with a unique sequence of Val‐Gly. ,	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10047551	Engagement of the PD-1 receptor with PD-L1 alters T cell activity, including the inhibition of T cell proliferation, survival, and cytokine production, as well as other T cell effector functions .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10529414	In this work, we found overexpression of TALAM1 in lung cancer (cell lines and primary cultured cells), and its expression was significantly higher in primary lung cancer samples.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11786704	3Effects of PC capsules on cell apoptosis and inflammatory factors. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "3Effects", "of", "PC", "capsules", "on", "cell", "apoptosis", "and", "inflammatory", ...
PMC10178190	Moreover, 2-hydroxyestardiol (2HE2), an estradiol metabolite that serves as a prodrug for 2-methoxyestradiol (2ME2) and converts efficiently to 2ME2, was also active in restoring platinum sensitivity to OC cells growing in direct contact with MSCs .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11788920	The circles around the lines are the data points obtained from five independent measurements and the lines are the average of these measurements. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11352666	Similarly, treatment with MRX-2843 resulted in a dose-dependent reduction in cell density relative to the vehicle in all five EWS cell lines (Figure 5A), with IC50 values ranging from 178 to 297 nM (Figure 5B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", ...
PMC10588957	Protein expression level of LC3II-LC3I ratio.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Protein", "expression", "level", "of", "LC3II-LC3I", "ratio", "." ] } ]
PMC11543885	Biotinylated proteins (BP) were visualized, and scale bars represent 50 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Biotinylated", "proteins", "(", "BP", ")", "were", "visualized", ...
PMC11629143	Histone acetylation has a greater influence on expression than CpG methylation at the CMV promoter. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Histone", "acetylation", "has", "a", "greater", "influ...
PMC5415764	Moreover, compared to the common P-gp inhibitors, TET demonstrates higher level of antitumor activities by suppressing cancer cell proliferation, inducing apoptosis and autophagy, and promoting reactive oxygen species (ROS) production678.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10170482	Contrast and brightness enhancement was performed using Macro 1 (supplemental macro material).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Contrast", "and", "brightness", "enhancement", "was", "performed", "us...
PMC9847912	In the second phase of the assay, samples of the 293T/17 supernatants (50 μl per well) were transferred to MAGIC-5A cultures to quantify infectious virus.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "...
PMC9429973	Eight (27.6%) patients did not require phlebotomy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Eight", "(", "27.6", "%", ")", "patients", "did", "not", "require", "phlebotomy", "." ...
PMC11676674	Hence, there was no correlation between induction of cytotoxicity and genotoxicity by C. monspeliensis extract in our study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hence", ",", "there", "was", ...
PMC11464982	All food enzymes currently on the EU market and intended to remain on that market, as well as all new food enzymes, shall be subjected to a safety evaluation by the European Food Safety Authority (EFSA) and approval via an EU Community list.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11641630	To confirm the dose of each experiment, representative mycobacterial suspensions of each treatment were serially diluted in PBS, and CFU were counted after plating on Middlebrook 7H10 medium as previously described .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11087766	All infections were imaged at 30 to 45 mpi. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "infections", "were", "imaged", "at", "30", "to", "45", "mpi", ".", "(" ] } ]
PMC6450504	Data shown indicate triplicate mean ± SD from blinded experiment. *	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "shown", "indicate", "triplicate", "mean", "±", "SD", "from", "blinded", "expe...
PMC9096373	Furthermore, there has been a lack of research on APA combination RT in cervical cancer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "there", "has", "been", "a", ...
PMC11787381	Then, mice were placed on a restraint tube to perform the single intravenous injection.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", "mice", "were", "placed", "on", "a", "res...
PMC11711127	Instead, polyclonal studies suggest a finer ‘tuned’ model of tolerance that is sometimes impermanent or otherwise restrained and resonates with our use of ‘resistance’ nomenclature.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11098378	HEK293T and BHK-21 cells were cultured in DMEM supplemented with 10% FBS.	[ { "tags": [ "B-CellLine", "I-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HEK293", "T", "and", "BHK-21", "cells", "were", ...
PMC11740207	The blastocyst forms around 5–6 days after fertilization (Figure 2); at this stage, the embryo consists of two main groups: the ICM, which will develop into the fetus, and the trophectoderm, which surrounds the ICM and contributes to forming structures like the placenta (Thomson et al., 1998).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5415764	To visualize the suppression effect of TET on the transport activity of P-gp, Rho 123, a fluorescent P-gp substrate, was employed to replace PTX.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7570809	Moreover, in addition to the well-established contribution of αvβ5 integrin to angiogenesis , much evidence supports the crucial role of this integrin in promoting cancer cell migration and invasion.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11063646	The formulated emulgels appeared white with an agreeable odor and a smooth and uniform consistency.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "formulated", "emulgels", "appeared", "white", "with", ...
PMC11786156	Twice as many distances between two extravascular DLBCL cells were arbitrarily selected without duplicated cells, measured, and compared to the intravascular distances between two DLBCL cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10547921	The α-amanitin cyclic peptide backbone forms a pocket that allows specific complementary hydrogen bonds to the Rpb1 His1085 side chain imidazole ring, creating a point of restraint for the Trigger Loo.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: To assess the impact of IVO+AZA versus placebo+AZA on health-related quality of life (HRQoL) using data from the AGILE study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9261184	The proportional contribution to total emissions from methane is indicated via the blue dots and the secondary axis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "proportional", "contribution", "to", ...
PMC8343815	The mechanism of the radiosensitizing effect of gold nanoparticles in the presence of megavoltage energies cannot be described by photoelectric absorption of Au.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC6617630	An unpaired Student t test was used for statistical comparisons and a *p value < 0.05 was considered significant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "An", "unpaired", "Student", ...
PMC10772747	Bcl-2 inhibits the release of cytochrome C and blocks the apoptotic pathway.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Bcl-2", "inhibits", "the", "release", "of", "cytochrome", "C", "and", "blocks", ...
PMC4360730	The ‘Organ’ facet represents the biosample slim described in the text describes the anatomical structure.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "‘", "Organ", "’", "facet", "represen...
PMC8068766	The Molecular Signatures Database (MSigDB) hallmark or GO-Biological Process data collection was used to search for enriched gene sets using the default “weighted” enrichment statistic parameter and “meandiv” normalization.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11045125	Mutu I is an EBV+ human BL cell line with type 1 latency.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mutu", "I", "is", "an", "EBV+", "human", "BL", "cell", ...
PMC10158546	The 96-well plates were sealed with optical adhesive film and run on FLUOstar Omega microplate readers (BMG) in 15-min cycles of double-orbital shaking followed by ThT fluorescence measurements (450 nm excitation and 480 nm emission) for a maximum of 50 h. We processed raw fluorescence data with MARS software (BMG) and...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8750422	Metastasis of the primary tumor to distant organs and resistance to therapeutic agents may be among several reasons for the poor prognosis associated with this subtype .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9243326	In addition, >5-kb size selection was performed using the BluePippin™ Size-Selection System and the resulting cDNA was mixed equally with non-size-selected cDNA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11484188	Therefore, autophagy serves an irreplaceable role in the survival of MM cells (11).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "autophagy", "serves", "an", "irrepla...
PMC11267830	f After the incubation of mouse liver, spleen and bone marrow cells with an anti-human CD45 antibody, the percentage of positive cells was quantitatively assessed and subjected to statistical analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8740518	High expression was associated with a poor prognosis, consistent with our findings.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "High", "expression", "was", "associated", "with", "a", "poor", "prognosis",...
PMC10936243	Similarly, all 20 veterinarians interviewed agreed that bedding provides comfortable post-operative recovery to their cat patient.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Similarly", ",", "all", "20", "veterinarians", ...
PMC11640555	In particular, treatments with CX-4945 at concentrations of 10 and 15 μM were able to increase the expression levels of pro-apoptotic proteins such as p53 and BID (Figure 3G and Figure 3H, densitometric analysis Figure 3(G1) and Figure 3(H1), respectively) when compared to the control group, which showed a low expressi...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11772585	The plate was then incubated in a cell culture incubator for 24 h. After incubation, the upper chamber was carefully removed, cells were fixed with polymethanol for 5 min, and stained with 0.1% crystal violet for 15 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11049294	In contrast, the DGJ-blocked cells will not degrade the substrate, thus via comparison of Fl-Gb3 to Fl-Gb3 + DGJ, the fluorescent ratio permits a precise, single-cell resolution measurement of AGAL activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11670954	Additionally, the involvement of the RhoA/ROCK2/MLCK pathway in the protective effect of BA against LPS-induced intestinal damage merits further investigation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", ...
PMC11078693	Acquire images with a confocal microscope, such as a Leica DMi8 microscope equipped with a Yokogawa CSU-W1 Spinning Disk and an Andor Zyla 4.2 sCMOS camera controlled by Andor Fusion software (problem 4).Note: The imaging parameters used were as follows: samples were mounted in PBS on a 63× NA1.2 water immersion lens.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11754784	The length of the edges of DNA cage is about 10 nm (30–32 bp).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "length", "of", "the", "edges", "of", "DNA...
PMC11568601	Data are presented as the mean ± SD (n = 3). **	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "presented", "as", "the", "mean", "±", ...
PMC11770130	Ntsr2 BKO mice also had increased expression of thermogenic genes in BATs but not in inguinal white adipose tissues (iWATs) (Supplementary information, Fig. S1k, l).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10452486	One of the primary roles of B2m in intact HLA class I (Face-1) is to provide a stable groove for the binding of peptides for antigen presentation to the CD8+ T lymphocytes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11798926	One alternative explanation is that either or both molecules could harbor a Golgi retention signal in the deleted region (Banfield, 2011), the removal of which could result in egress from the Golgi.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10998613	The interaction is weaker in the noncancer cell lines CHO and COS-7 cells, but significant in the cancer cell lines, MDA-MB-231 and HCC4006.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-...
PMC11291490	Statistical significance was assessed using an unpaired Student’s t-test.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "significance", "was", "assessed", "using", "an", "unpaired", "Student", "’s", "t-...
PMC11525293	Taken together, these results clearly indicate that ACE2 is a new target gene of ΔNp63α.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Taken", "together", ",", "these", "results", "clearly"...
PMC7602170	Activated RTKs, such as c-KIT and PDGFRA, activate multiple intracellular signaling pathways, including PI3K/AKT/mTOR, Ras/RAF/ERK and JAK/STAT signaling.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Activated", ...
PMC11750712	Unexpectedly, no alteration of the peripheral blood (PB) TRBC1:TRBC2 ratio was seen, suggesting lack of CAR T cell-mediated depletion of normal TRBC1 T cells (Extended Data Fig. 3b,c).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9479186	Wound-healing assay and transwell assay indicated that the downregulation of NDUFC1 suppressed the migration and invasion of HCC cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Wound-healing", "assay", "and", "...
PMC9429973	The diagnosis included T cell lymphoblastic lymphoma(T-LBL,n=8),hepatosplenic T-cell lymphoma(HSTL,n=1)and monomorphic epitheliotropic intestinal T-cell lymphoma(MEITL,n=1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "diagnosis", ...
PMC10568263	We found that some immunosensors in Table 1 have a linear detection range that can reach the fg mL level, but their upper limit does not cover the average concentration of HSP70 detectable in healthy humans and cancer patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11740399	CCK8 analysis (F) proved that the ML did not affect the proliferation ability of tumor cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CCK8", "analysis", "(", "F", ")", ...
PMC10123657	Transfer, hybridization, and visualization were made as previously reported .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Transfer", ",", "hybridization", ",", "and", "visualization", "were", "made", "as", "...
PMC9429973	Results: Fifty-eight ITP were collected, 22 were severe newly diagnosed ITP and 36 were those with poor response to first-line therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results...
PMC6835428	In conclusion, although the above issues may dampen enthusiasm for future research in the OC area with regard to siRNAs, the development of effective delivery systems should be further pursued.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10329237	ZO-1 and E-cadherin expression were significantly decreased, while Vimentin, β-Catenin, and α-SMA expressions were significantly increased in BLM-stimulated EMT.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ZO-1", "and"...
PMC11637276	MDA-MB-231 cells were transfected with an siRNA targeting MAPK3K1 (siMAP3K1), an siRNA targeting MAPK11 (siMAPK11), an siRNA targeting PPP2R1A (siPPP2R1A) or a non-targeting siRNA control (siNT), seeded on pHrodo-labelled CDM for 6 h, stained with 1 μg/ml Hoechst and imaged live.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10854447	A cell viability experiment was performed on the MCF-10A (normal human mammary gland epithelial) cell line to assess the effect of compounds 7a–o on normal cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11407042	Culture cells at 37°C with 5% CO2 and 95% humidity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Culture", "cells", "at", "37", "°", "C", "with", "5", "%",...
PMC10758402	Biological replicates are indicated by a number n, and error calculated as the standard error of the mean (SEM) For all analyses, p < 0.05, p < 0.01, p < 0.001, **p < 0.0001; n.s.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9844987	Top: density plot of promoter expression per gene category.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Top", ":", "density", "plot", "of", "promoter", "expression", "per", "gene", "category", "...
PMC9429973	Multivariate analysis demonstrated that high plasmatic TAC is an independent prognostic factor for OS that allows the identification of patients with inferior OS in both DIPSS lowest and highest categories.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10243817	Total RNA was extracted from human tissue and cell samples by using TRIzol reagent (InvitroGen).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Total", "RNA", "was", "extracted", "from", ...
PMC11519077	In comparison to undifferentiated MSCs, alkaline phosphatase expression levels in differentiated MSCs into the osteocyte lineage were considerably higher (Figure 4).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10135767	Cells were grown in a 5% CO2 cell culture incubator (Thermo Fisher Scientific, Shanghai, China) at 37 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11643361	The successful history of cisplatin, discovered in 1966 to be a potent trans-domain cell division inhibitor and used either alone or as a co-adjuvant almost as a go-to anticancer drug, has recently led to an intensive exploration of novel prototypical cancer drugs .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11752740	Results are presented as Mean ± SD compared to control Dose-Response curve showing the effects of pistachio hull extract (E) (mg/ml) and carfilzomib (CFZ) (mg/ml) on SK-BR3 and MCF10A cell lines at 24- and 48-hours post-treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Nevertheless, there was a persistent age differential in the PLEL over time.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Nevertheless", ",", "there", "was", "a", "persistent", "age", "differential...
PMC11695623	Correlation of DCUN1D5 with different immune infiltrating cells in TCGA-LUAD dataset. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Correlation", "of", "DCUN1D5", "with", "different", "immune", "infiltrating", "cells",...
PMC9429973	CAR expression was measured up to 15 days post-transduction by flow cytometry.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CAR", "expression", "was", "measured", "up", "to", "15", "days", "post-transduct...
PMC9454852	After crystal violet staining, colonies containing more than 50 cells were counted and evaluated .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "crystal", "violet", "staining", ",", "colonies", "...
PMC11695623	We only use the data in TCGA to analyze the biological function of DCUN1D5, and then we should include more samples from different databases for verification.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11367146	Cells treated with IL-1β (10 ng/ml) for 2 h followed by different doses (50 and 100 μg/ml) of VTE and incubated for 24 h. The graph is plotted by integrating mean ± SD (n = 3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The presence of anti-Tregs was investigated in 7 pts, by ELISPOT assay on patient T cells that had been stimulated with epitopes derived from the immunosuppressive proteins ARG, IDO or TGFβ.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10079526	U2OS cells cultured on glass cover slips were treated with 1 µM 5-Aza-2’ and/or 1 µM TAK981 or DMSO 0.1% as control for 4 or 20 h. Slides were stained with DNMT1 and γH2Ax antibodies.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Siremadlin is a selective inhibitor of the p53-MDM2 interaction.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Siremadlin", "is", "a", "selective", "inhibitor", "of", "the", "p53-MDM2", "interaction", "." ] } ]
PMC9429973	The burden is not only physical pain, but also includes psychological and social dimensions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "burden", "is", "not", "only", "physical", "pain", ...
PMC11711663	detailing the features selected, log-rank test statistic, score test statistic, training CI (concordance index), and independent CI.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "detaili...
PMC2777936	This is in agreement with our earlier studies using degenerate PCR primers for Wnt ligand analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "is", "in", "agreement", "with", "our", "...
PMC10975211	The second category of AMPs focuses on non-disruptive cell wall interactions (intracellular targets—altering protein synthesis, enzyme activity, binding, and interfering in DNA and RNA replication) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11698348	Elf5 has been shown to be a critical transcriptional regulator of cell fate in stem/progenitor cells by regulating target genes, such as, BMP, GATA3 and Notch signalling pathways [4–6], which are involved in cell proliferation and differentiation processes in development of epithelial tissues including the kidney and m...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11767817	Complexes between CDK1 and cyclins A and B are required for mitosis .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Complexes", "between", "CDK1", "and", "cyclins", "A", "and", "B", "are", "...
PMC11544122	Data were analyzed by one-way ANOVA (a) or Student’s t-test (c).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "were", "analyzed", "by", "one-way", "ANOVA", ...
PMC6024716	Cell line: HEK293 stably transfected with the luciferase gene of Photinus pyralis under a cytomegalovirus (CMV) promoter (CMV-Luc2-Hygro HEK293, Promega ID# CAS140901, Madison, WI, USA).	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9985266	P < 0.05, P < 0.01, *P < 0.001; values are expressed as the mean ± standard deviation (n = 3) Consistent with previous findings , our results showed that the level of IL-27 in BLM-induced PF mice first increased and then gradually decreased.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11574029

Consistent with the in vitro results, the inhibitory effects of targeting NOTCH3 on tumor growth and metastasis were counteracted by SPP1 overexpression.

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PMC9429973

Therefore, automated LIC measurements using artificial intelligence (AI) or deep-learning-assessed (DLA) algorithms could provide the solution for globally affordable and reliable patient monitoring of LIC.

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PMC11519567

Data are mean±s.d.,

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PMC9429973

In addition, gut microbiota plays a key role in the efficacy and toxicity of antitumor treatments, especially immunotherapy.

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PMC11389534

UFM1 is initially synthesised as a precursor molecule, proUFM1, which then undergoes processing by UFM1‐specific protease 1 (UFSP1) and UFM1‐specific protease 2 (UFSP2), , , , , resulting in a mature UFM1 with a unique sequence of Val‐Gly. ,

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PMC10047551

Engagement of the PD-1 receptor with PD-L1 alters T cell activity, including the inhibition of T cell proliferation, survival, and cytokine production, as well as other T cell effector functions .

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PMC10529414

In this work, we found overexpression of TALAM1 in lung cancer (cell lines and primary cultured cells), and its expression was significantly higher in primary lung cancer samples.

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PMC11786704

3Effects of PC capsules on cell apoptosis and inflammatory factors. (

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PMC10178190

Moreover, 2-hydroxyestardiol (2HE2), an estradiol metabolite that serves as a prodrug for 2-methoxyestradiol (2ME2) and converts efficiently to 2ME2, was also active in restoring platinum sensitivity to OC cells growing in direct contact with MSCs .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11788920

The circles around the lines are the data points obtained from five independent measurements and the lines are the average of these measurements. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11352666

Similarly, treatment with MRX-2843 resulted in a dose-dependent reduction in cell density relative to the vehicle in all five EWS cell lines (Figure 5A), with IC50 values ranging from 178 to 297 nM (Figure 5B).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", ...

PMC10588957

Protein expression level of LC3II-LC3I ratio.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Protein", "expression", "level", "of", "LC3II-LC3I", "ratio", "." ] } ]

PMC11543885

Biotinylated proteins (BP) were visualized, and scale bars represent 50 μm.

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PMC11629143

Histone acetylation has a greater influence on expression than CpG methylation at the CMV promoter. (

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PMC5415764

Moreover, compared to the common P-gp inhibitors, TET demonstrates higher level of antitumor activities by suppressing cancer cell proliferation, inducing apoptosis and autophagy, and promoting reactive oxygen species (ROS) production678.

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PMC10170482

Contrast and brightness enhancement was performed using Macro 1 (supplemental macro material).

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PMC9847912

In the second phase of the assay, samples of the 293T/17 supernatants (50 μl per well) were transferred to MAGIC-5A cultures to quantify infectious virus.

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PMC9429973

Eight (27.6%) patients did not require phlebotomy.

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PMC11676674

Hence, there was no correlation between induction of cytotoxicity and genotoxicity by C. monspeliensis extract in our study.

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PMC11464982

All food enzymes currently on the EU market and intended to remain on that market, as well as all new food enzymes, shall be subjected to a safety evaluation by the European Food Safety Authority (EFSA) and approval via an EU Community list.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11641630

To confirm the dose of each experiment, representative mycobacterial suspensions of each treatment were serially diluted in PBS, and CFU were counted after plating on Middlebrook 7H10 medium as previously described .

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PMC11087766

All infections were imaged at 30 to 45 mpi. (

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PMC6450504

Data shown indicate triplicate mean ± SD from blinded experiment. *

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PMC9096373

Furthermore, there has been a lack of research on APA combination RT in cervical cancer.

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PMC11787381

Then, mice were placed on a restraint tube to perform the single intravenous injection.

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PMC11711127

Instead, polyclonal studies suggest a finer ‘tuned’ model of tolerance that is sometimes impermanent or otherwise restrained and resonates with our use of ‘resistance’ nomenclature.

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PMC11098378

HEK293T and BHK-21 cells were cultured in DMEM supplemented with 10% FBS.

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PMC11740207

The blastocyst forms around 5–6 days after fertilization (Figure 2); at this stage, the embryo consists of two main groups: the ICM, which will develop into the fetus, and the trophectoderm, which surrounds the ICM and contributes to forming structures like the placenta (Thomson et al., 1998).

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PMC5415764

To visualize the suppression effect of TET on the transport activity of P-gp, Rho 123, a fluorescent P-gp substrate, was employed to replace PTX.

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PMC7570809

Moreover, in addition to the well-established contribution of αvβ5 integrin to angiogenesis , much evidence supports the crucial role of this integrin in promoting cancer cell migration and invasion.

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PMC11063646

The formulated emulgels appeared white with an agreeable odor and a smooth and uniform consistency.

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PMC11786156

Twice as many distances between two extravascular DLBCL cells were arbitrarily selected without duplicated cells, measured, and compared to the intravascular distances between two DLBCL cells.

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PMC10547921

The α-amanitin cyclic peptide backbone forms a pocket that allows specific complementary hydrogen bonds to the Rpb1 His1085 side chain imidazole ring, creating a point of restraint for the Trigger Loo.

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PMC9429973

Aims: To assess the impact of IVO+AZA versus placebo+AZA on health-related quality of life (HRQoL) using data from the AGILE study.

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PMC9261184

The proportional contribution to total emissions from methane is indicated via the blue dots and the secondary axis.

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PMC8343815

The mechanism of the radiosensitizing effect of gold nanoparticles in the presence of megavoltage energies cannot be described by photoelectric absorption of Au.

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PMC6617630

An unpaired Student t test was used for statistical comparisons and a *p value < 0.05 was considered significant.

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PMC10772747

Bcl-2 inhibits the release of cytochrome C and blocks the apoptotic pathway.

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PMC4360730

The ‘Organ’ facet represents the biosample slim described in the text describes the anatomical structure.

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PMC8068766

The Molecular Signatures Database (MSigDB) hallmark or GO-Biological Process data collection was used to search for enriched gene sets using the default “weighted” enrichment statistic parameter and “meandiv” normalization.

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PMC11045125

Mutu I is an EBV+ human BL cell line with type 1 latency.

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PMC10158546

The 96-well plates were sealed with optical adhesive film and run on FLUOstar Omega microplate readers (BMG) in 15-min cycles of double-orbital shaking followed by ThT fluorescence measurements (450 nm excitation and 480 nm emission) for a maximum of 50 h. We processed raw fluorescence data with MARS software (BMG) and...

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PMC8750422

Metastasis of the primary tumor to distant organs and resistance to therapeutic agents may be among several reasons for the poor prognosis associated with this subtype .

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PMC9243326

In addition, >5-kb size selection was performed using the BluePippin™ Size-Selection System and the resulting cDNA was mixed equally with non-size-selected cDNA.

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PMC11484188

Therefore, autophagy serves an irreplaceable role in the survival of MM cells (11).

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PMC11267830

f After the incubation of mouse liver, spleen and bone marrow cells with an anti-human CD45 antibody, the percentage of positive cells was quantitatively assessed and subjected to statistical analysis.

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PMC8740518

High expression was associated with a poor prognosis, consistent with our findings.

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PMC10936243

Similarly, all 20 veterinarians interviewed agreed that bedding provides comfortable post-operative recovery to their cat patient.

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PMC11640555

In particular, treatments with CX-4945 at concentrations of 10 and 15 μM were able to increase the expression levels of pro-apoptotic proteins such as p53 and BID (Figure 3G and Figure 3H, densitometric analysis Figure 3(G1) and Figure 3(H1), respectively) when compared to the control group, which showed a low expressi...

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PMC11772585

The plate was then incubated in a cell culture incubator for 24 h. After incubation, the upper chamber was carefully removed, cells were fixed with polymethanol for 5 min, and stained with 0.1% crystal violet for 15 min.

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PMC11049294

In contrast, the DGJ-blocked cells will not degrade the substrate, thus via comparison of Fl-Gb3 to Fl-Gb3 + DGJ, the fluorescent ratio permits a precise, single-cell resolution measurement of AGAL activity.

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PMC11670954

Additionally, the involvement of the RhoA/ROCK2/MLCK pathway in the protective effect of BA against LPS-induced intestinal damage merits further investigation.

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PMC11078693

Acquire images with a confocal microscope, such as a Leica DMi8 microscope equipped with a Yokogawa CSU-W1 Spinning Disk and an Andor Zyla 4.2 sCMOS camera controlled by Andor Fusion software (problem 4).Note: The imaging parameters used were as follows: samples were mounted in PBS on a 63× NA1.2 water immersion lens.

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PMC11754784

The length of the edges of DNA cage is about 10 nm (30–32 bp).

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PMC11568601

Data are presented as the mean ± SD (n = 3). **

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PMC11770130

Ntsr2 BKO mice also had increased expression of thermogenic genes in BATs but not in inguinal white adipose tissues (iWATs) (Supplementary information, Fig. S1k, l).

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PMC10452486

One of the primary roles of B2m in intact HLA class I (Face-1) is to provide a stable groove for the binding of peptides for antigen presentation to the CD8+ T lymphocytes.

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PMC11798926

One alternative explanation is that either or both molecules could harbor a Golgi retention signal in the deleted region (Banfield, 2011), the removal of which could result in egress from the Golgi.

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PMC10998613

The interaction is weaker in the noncancer cell lines CHO and COS-7 cells, but significant in the cancer cell lines, MDA-MB-231 and HCC4006.

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PMC11291490

Statistical significance was assessed using an unpaired Student’s t-test.

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PMC11525293

Taken together, these results clearly indicate that ACE2 is a new target gene of ΔNp63α.

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PMC7602170

Activated RTKs, such as c-KIT and PDGFRA, activate multiple intracellular signaling pathways, including PI3K/AKT/mTOR, Ras/RAF/ERK and JAK/STAT signaling.

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PMC11750712

Unexpectedly, no alteration of the peripheral blood (PB) TRBC1:TRBC2 ratio was seen, suggesting lack of CAR T cell-mediated depletion of normal TRBC1 T cells (Extended Data Fig. 3b,c).

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PMC9479186

Wound-healing assay and transwell assay indicated that the downregulation of NDUFC1 suppressed the migration and invasion of HCC cells.

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PMC9429973

The diagnosis included T cell lymphoblastic lymphoma(T-LBL,n=8),hepatosplenic T-cell lymphoma(HSTL,n=1)and monomorphic epitheliotropic intestinal T-cell lymphoma(MEITL,n=1).

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PMC10568263

We found that some immunosensors in Table 1 have a linear detection range that can reach the fg mL level, but their upper limit does not cover the average concentration of HSP70 detectable in healthy humans and cancer patients.

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PMC11740399

CCK8 analysis (F) proved that the ML did not affect the proliferation ability of tumor cells.

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PMC10123657

Transfer, hybridization, and visualization were made as previously reported .

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PMC9429973

Results: Fifty-eight ITP were collected, 22 were severe newly diagnosed ITP and 36 were those with poor response to first-line therapy.

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PMC6835428

In conclusion, although the above issues may dampen enthusiasm for future research in the OC area with regard to siRNAs, the development of effective delivery systems should be further pursued.

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PMC10329237

ZO-1 and E-cadherin expression were significantly decreased, while Vimentin, β-Catenin, and α-SMA expressions were significantly increased in BLM-stimulated EMT.

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PMC11637276

MDA-MB-231 cells were transfected with an siRNA targeting MAPK3K1 (siMAP3K1), an siRNA targeting MAPK11 (siMAPK11), an siRNA targeting PPP2R1A (siPPP2R1A) or a non-targeting siRNA control (siNT), seeded on pHrodo-labelled CDM for 6 h, stained with 1 μg/ml Hoechst and imaged live.

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PMC10854447

A cell viability experiment was performed on the MCF-10A (normal human mammary gland epithelial) cell line to assess the effect of compounds 7a–o on normal cell lines.

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PMC11407042

Culture cells at 37°C with 5% CO2 and 95% humidity.

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PMC10758402

Biological replicates are indicated by a number n, and error calculated as the standard error of the mean (SEM) For all analyses, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001; n.s.

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PMC9844987

Top: density plot of promoter expression per gene category.

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PMC9429973

Multivariate analysis demonstrated that high plasmatic TAC is an independent prognostic factor for OS that allows the identification of patients with inferior OS in both DIPSS lowest and highest categories.

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PMC10243817

Total RNA was extracted from human tissue and cell samples by using TRIzol reagent (InvitroGen).

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PMC11519077

In comparison to undifferentiated MSCs, alkaline phosphatase expression levels in differentiated MSCs into the osteocyte lineage were considerably higher (Figure 4).

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PMC10135767

Cells were grown in a 5% CO2 cell culture incubator (Thermo Fisher Scientific, Shanghai, China) at 37 °C.

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PMC11643361

The successful history of cisplatin, discovered in 1966 to be a potent trans-domain cell division inhibitor and used either alone or as a co-adjuvant almost as a go-to anticancer drug, has recently led to an intensive exploration of novel prototypical cancer drugs .

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PMC11752740

Results are presented as Mean ± SD compared to control Dose-Response curve showing the effects of pistachio hull extract (E) (mg/ml) and carfilzomib (CFZ) (mg/ml) on SK-BR3 and MCF10A cell lines at 24- and 48-hours post-treatment.

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PMC9429973

Nevertheless, there was a persistent age differential in the PLEL over time.

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PMC11695623

Correlation of DCUN1D5 with different immune infiltrating cells in TCGA-LUAD dataset. (

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PMC9429973

CAR expression was measured up to 15 days post-transduction by flow cytometry.

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PMC9454852

After crystal violet staining, colonies containing more than 50 cells were counted and evaluated .

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PMC11695623

We only use the data in TCGA to analyze the biological function of DCUN1D5, and then we should include more samples from different databases for verification.

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PMC11367146

Cells treated with IL-1β (10 ng/ml) for 2 h followed by different doses (50 and 100 μg/ml) of VTE and incubated for 24 h. The graph is plotted by integrating mean ± SD (n = 3).

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PMC9429973

The presence of anti-Tregs was investigated in 7 pts, by ELISPOT assay on patient T cells that had been stimulated with epitopes derived from the immunosuppressive proteins ARG, IDO or TGFβ.

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PMC10079526

U2OS cells cultured on glass cover slips were treated with 1 µM 5-Aza-2’ and/or 1 µM TAK981 or DMSO 0.1% as control for 4 or 20 h. Slides were stained with DNMT1 and γH2Ax antibodies.

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PMC9429973

Siremadlin is a selective inhibitor of the p53-MDM2 interaction.

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PMC9429973

The burden is not only physical pain, but also includes psychological and social dimensions.

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PMC11711663

detailing the features selected, log-rank test statistic, score test statistic, training CI (concordance index), and independent CI.

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PMC2777936

This is in agreement with our earlier studies using degenerate PCR primers for Wnt ligand analysis.

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PMC10975211

The second category of AMPs focuses on non-disruptive cell wall interactions (intracellular targets—altering protein synthesis, enzyme activity, binding, and interfering in DNA and RNA replication) .

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PMC11698348

Elf5 has been shown to be a critical transcriptional regulator of cell fate in stem/progenitor cells by regulating target genes, such as, BMP, GATA3 and Notch signalling pathways [4–6], which are involved in cell proliferation and differentiation processes in development of epithelial tissues including the kidney and m...

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PMC11767817

Complexes between CDK1 and cyclins A and B are required for mitosis .

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PMC11544122

Data were analyzed by one-way ANOVA (a) or Student’s t-test (c).

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PMC6024716

Cell line: HEK293 stably transfected with the luciferase gene of Photinus pyralis under a cytomegalovirus (CMV) promoter (CMV-Luc2-Hygro HEK293, Promega ID# CAS140901, Madison, WI, USA).

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PMC9985266

P < 0.05, **P < 0.01, ***P < 0.001; values are expressed as the mean ± standard deviation (n = 3) Consistent with previous findings , our results showed that the level of IL-27 in BLM-induced PF mice first increased and then gradually decreased.

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