OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11775197	Fenofibrate also reduces cancer cells’ invasion and migration ability .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fenofibrate", "also", "reduces", "cancer", "cells", "’", "invasion", "and", "migration", "abilit...
PMC8864075	In summary, reTFAE can inhibit the PI3K/Akt pathway with the core of TWIST1, thereby inhibiting the glycolytic pathway to suppress EMT in A549 cells (Figure 5).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", ...
PMC11534377	FOXO3, involved in apoptosis and cell cycle regulation, displayed a notable increase in expression in the treated cells (P = 0.0008), suggesting an enhanced pro-apoptotic response.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11791203	Early apoptotic cells were characterized by green fluorescence, while late apoptotic or necrotic cells exhibited red fluorescence.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Early", "apoptotic", "cells", "were", ...
PMC11727638	The downregulation of CD20 was also observed on KML-1 cells cultured in the Cell Dome, where CD20 expression was gradually downregulated with increasing culture periods.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11576293	The signal transduction of EGFR tyrosine kinase is strongly linked to tumor progression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "signal", "transduction", "of", "EGFR", "tyrosine", "kinase", "is", ...
PMC9429973	Image: Summary/Conclusion: This analysis reveals that pts across all PKLR genotypes experienced a wide range of serious comorbidities/complications across multiple systems.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Image",...
PMC11703992	CD40LG and IL16-CD4 L-R pairs maintain inflammation response by enhancing the activation of APCs and the production of pro-inflammatory cytokines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CD40LG", "and", "IL16-CD4", ...
PMC11298021	Then, 100 µL of dimethyl sulfoxide (DMSO, Sigma, USA) was added to dissolve the formazan crystals.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", "100"...
PMC6379402	We do this by clustering genes in different networks and by computing the enrichment of the clusters in biological annotations (see details in Methods, section Enrichment-based measures).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9545474	High‐resolution ESI‐MS was obtained for complexes 4–8 and confirmed the proposed structures (Figures S18–S22).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "High‐resolution", "ESI‐MS", "was", "obtained", "for", ...
PMC11194678	Data were collected from three independent batches of cultures.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "were", "collected", "from", "three", "independent", "batches", "of", "cultures", "." ] } ]
PMC11541241	The plant‐derived compound antofine could be another inhibitor to dissect the TOR signalling function and may be used as a biofungicide to control plant fungal disease.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9622879	It also helps to increase the benefits for prosumers because the pricing proposed by the LEM is usually better than that of the electricity provider.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10969097	The study involved 40 patients divided into two groups, with one group (n = 19) receiving the Andosan™ extract and the other group (n = 21) receiving a placebo, both in conjunction with chemotherapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	GOFC demonstrated a low correlation with predictive accuracy; thus, limited weight should be assigned to GOFC when selecting the optimal survival model in LBCL.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11129910	These RAB25-downregulated cell lines became the model for our study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "RAB25-downregulated", "cell", "lines", "became", "the", "model", "for", "our", "study",...
PMC9429973	Image: Summary/Conclusion: ARI0002h is the first European academic CART for RRMM that has demonstrated deep and durable responses and a favorable safety profile, including the absence of neurotoxicity and the feasibility of a second booster dose.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11012012	The effects of SLAMF7/CD319 on B cell proliferation were shown on both naive and memory B cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "effects", "of", "SLAMF7/CD319", "on", ...
PMC11297139	The representative images supported by the relevant statistics have been chosen upon three independent preparations with similar outcomes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "representative", "images", "supported...
PMC11792766	Ethanol as such seems to interfere with the function of the NRU assay.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ethanol", "as", "such", "seems", "to", "interfere", "with", "the", "f...
PMC7185206	Similar results were seen in the MB-MDA-231 breast cancer cell line (Supplemental Figure 6a).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "B-CellLine", "I-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Similar", "results", "were"...
PMC11469524	While such models help to gain the understanding of pathway interactions, they are not suitable for simulations or quantitative model comparisons.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "While", "suc...
PMC11477621	C NMR (100 MHz, CDCl3) δ 188.3, 173.9, 130.3, 130.1, 120.4, 108.0, 60.3, 49.8, 34.3, 31.4, 28.8, 27.5, 26.4, 24.9, 14.4.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11748618	Antiretroviral therapy has greatly improved the quality of life of people living with HIV and limited the spread of the virus, but the accumulation of escape mutations may threaten the long-term use of ART.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7602170	The eIF4F complex consists of three polypeptides (eIF4E, eIF4A and eIF4G).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "eIF4F", "complex", "consists", "of", "three", "polyp...
PMC11747467	A trial involving 23 metastatic breast cancer patients treated with ART reported nonsevere ART-related adverse events affecting the auditory system (46, 47).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC3681794	B, 48 hours after exposure to a 1 hour pulse of doxorubicin (10 µM), etoposide (500 µM) or cisplatin (75 µM) in normoxia or hypoxia U2OS cells were stained with DAPI and morphologically apoptotic cells counted with a fluorescent microscope.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11670407	The values are expressed as means ± S.D.s. *	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "values", "are", "expressed", "as", "means", "±", "S.D.s", ".", "*" ] } ]
PMC11697065	Viable cell density and cell viability were assessed using a Vi-Cell XR automated cell counter and viability analyser (Beckman Coulter, High Wycombe, UK).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11240448	Although 33 different luminal BC cell lines have distinct mutational and expression profiles, the inferred architecture of causal connections of core networks in these cell lines is similar, and oncogenesis is mainly driven by the mTOR pathway.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9268620	Necrosis, on the other hand, is known as untimely cell death that happens as a consequence of extreme and uncontrollable external factors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11750712	In patients with a TRBC1 PTCL, CAR T cells directed against TRBC1 should target the lymphoma, but spare healthy TRBC2 T cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11725127	Two primary strategies to tackle cancers with KRAS mutations involve either the direct inhibition of KRAS activity or the induction of its degradation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Two", ...
PMC11222184	Villa et al. showed that the HSP90 inhibitors 17-AAG and Geldanamycin caused a significant inhibition of telomerase activity in JR8 human melanoma cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	In contrast, the RS for patients with isolated adult pLCH at the same time points were 98.3%, 94.8%, 90.9% (Figure).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11047729	Meanwhile, I3C caused the down-regulation of c-Myc—a transcription factor that regulates the hTERT gene transcription.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Meanwhile", ",", "I3C", "caused", "the...
PMC8540692	Contrarily, in another colon carcinoma cell line, HCT-116, NaBu upregulated the expression of these promoters .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Contrarily", ",", "in", "another", ...
PMC11742431	Immediately afterward, the expression levels of Survivin in pan‐cancer were analyzed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Immediately", "afterward", ",", "the", "expression", "levels", "of", "Survivin", ...
PMC11767817	Based on these results, the MK-2206 concentration of 5 μM was selected for further experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Based", "on", "these", "results", ",", "the", "M...
PMC9429973	Results: As of 23 July 2021, the median follow-up among all treated patients in Phase 2 (N=55) was 26.8 months (range, 20.7-32.6).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9621239	The number of the significant sites which have higher mutation frequencies, located within the transactivation domain or strongly conserved region are displayed in the Venn diagram. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: To describe the multiple-adjudication methodology employed to confirm diagnosis of TA-TMA across adult and pediatric transplant centers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "To", "describe", ...
PMC9429973	Protein expression analysis of carfilzomib sensitive vs. resistant cell line variants indicate alterations of BCL2 family members (MCL-1, BCL-xL, BCL-2, BAD, BID, BAX, BAK, BIM, NOXA and PUMA) in untreated conditions as well as under carfilzomib treatment (Figure 1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11528603	Apoptosis and proliferation–related gene expression at 24-hour time point of treatment. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Apoptosis", "and", "proliferation", "–", "related", "gene", "expressio...
PMC11697703	After IUE at E15 of miR193b, miR-365, both miR193b and miR-365, or scrambled miRNA, we analyzed the presence of heterotopic clusters of neurons that failed to migrate into the superficial layers at P14.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Informed consent was obtained from all participants.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Informed", "consent", "was", "obtained", "from", "all", "participants", "." ] } ]
PMC11406030	The MTT assay was used to determine cytotoxicity after treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "MTT", "assay", "was", "used", "to", "determine", "cytotoxicity", "after", "treatment", ...
PMC11394730	Quercetin also decreased the potential of the mitochondrial membrane in malignant glioma cells U373MG.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O" ], "tokens": [ "Quercetin", "also", "decreased", "the", "potential", "of", "t...
PMC5034105	A ⩾2 log increase in mean viral load with ZIKV-NS1 protein expression and CPE were observed in the nonhuman primate (Vero and LLC-MK2), pig (PK-15), rabbit (RK-13), hamster (BHK21) and chicken (DF-1) cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "...
PMC8303372	The optical density (OD) of the solutions in each well was determined using an automatic microplate photometer (ELx800; BioTek, Bad Friedrichshall, Germany) at a wavelength of 570 nm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5963610	The pain, skin rash and sequential computed tomography (TAC) from tumors, life´s condition and disease were analyzed during 15 years.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11742290	High expression of LGR5 in ovarian cancer cells was associated with carboplatin, cisplatin, and taxol resistance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "High", "expression", "of", "LGR5", "in...
PMC9351137	These results suggested that the mitotic localizations of the CRS reflect intrinsic properties of the proteins, independently of the cell type.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "res...
PMC8382973	The primary physicochemical properties commonly assessed for semisolids include osmolality, viscosity, and pH. Osmolality was measured to determine how the drug deviated from isosmolar (290 mOsmol/kg) conditions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11106977	Since its discovery, researchers have demonstrated O-GlcNAcylation on thousands of proteins implicated in numerous different biological processes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Since", "its", "discovery", ",", "rese...
PMC11078693	Biotium kits can work with both carrier-free and some non-carrier-free antibodies; see manufacturer protocol for details: https://biotium.com/wp-content/uploads/2017/10/PI-Mix-n-Stain-Antibody-Labeling-Kits.pdf.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Biotium", "kits", "can", "work", ...
PMC11411004	The degree of histone acetylation can be regulated by HDACis, and transgene expression in recombinant CHO monoclonal antibodies can be enhanced after treatment with NaBu HDACi (Nmagu et al. 2021).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10154881	Accumulation of tumor antigen‐specific CTLs induced by rMV‐SLAMblind cancer therapy. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Accumulation", "of", "tumor", "antigen‐specific", "CTLs", "induced", "by", "rMV‐SLAMblind", ...
PMC9370419	The human hepatoma Huh7 cell line and HepG2-derived 2.2.15 cell line (constitutively producing HBV Dane particles) were kindly provided by the Cell Bank, Chinese Academy of Sciences (Shanghai, China).	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "B-CellLine", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC11711063	The increased occupancy by ARID1A and reduced H3K27 acetylation at the proximal regulatory region of the ZG16B gene were confirmed by qPCR (Figure 1B,C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	1% pts discontinued due to TEAEs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "1", "%", "pts", "discontinued", "due", "to", "TEAEs", "." ] } ]
PMC8735881	As expected, two mutants, CMI02/P41m and CMI06/P41m, were well expressed on the surface of transduced TZM-bl and 293FTTarget cells without affecting the HIV receptor and coreceptors either (Fig. S6); however, they exhibited similar activities with GPI-10E8 in inhibiting the infections of HIV-1 SF162 and SIV mac239 (Fig...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "...
PMC11535726	Unlike K.crustacea, K.longirostrata has cylindrical, proliferating conidiogenous cells and obpyriform to obclavate conidia, with longer (15–100(–120) × 2.5–6 μm), guttulate, proliferating rostrate structures and a mucilaginous sheath surrounding the upper part of the apex.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5173112	To examine the cell invasion, 1 × 10 siRNA-transfected cells were plated on Matrigel invasion chambers (Corning, NY, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11766309	The highest and lowest risk effects were found for the KICH (HR = 6.964, p=0.026) and HNSC (HR=1.337, p=0.013) cancers, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Of those, only 3 (5%) and 1 (2%) harbored NPM1 and FLT3-ITD mutations, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Of", "those"...
PMC9024365	Quantification indicates no significant increase in the mean area of clusters after the 4C incubation (Figure 7B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Quantification", "indicates", "no", ...
PMC11786704	Defective diabetic wound healing is a major clinical challenge, where hyperglycemia at the wound site induces excessive reactive oxygen species (ROS) which activate the MAPK pathway (particularly p38 MAPK), resulting in sustained release of inflammatory factors and cellular damage/apoptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11770199	Eight hours after transfection, human MSCs-tet-p14 were digested and mixed with melanoma cells A375 and MV3 expressed with GFP protein, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens"...
PMC11705630	Statistical analysis was conducted using Student's t-test or one-way ANOVA for more than two groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "analysis", "was", "conducted", "using", ...
PMC11731161	We analyzed the subcellular localization of RanBP1 following blocking XPO1 degradation by MG132.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "analyzed", "the", "subcellular", "localization", "of", "RanBP1", "fol...
PMC11700165	2Phosphorylation and inhibition mechanisms of SYK fusion kinases. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "2Phosphorylation", "and", "inhibition", "mechanisms", "of", "SYK", "fusion", "kinases", ".", "(" ] } ...
PMC10965680	Identification of selective signals in Xiangdong goats.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Identification", "of", "selective", "signals", "in", "Xiangdong", "goats", "." ] } ]
PMC11740207	By comparing these datasets with scRNA-seq results from morula, blastula, gastrula and VSELSC and/or VSLSLC stages, researchers can identify both shared and unique molecular signatures among these cell groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11680049	For explants placed on WPM, primary callus formation was primarily characterized on the leaf blade, predominantly in the mesophyll area near the midrib, while for explants placed on MS medium, it was noted on the stem in the internodes and meristems (Figure 4a,b).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11352666	Treatment with MRX-2843, a first-in-class, MERTK-selective tyrosine kinase inhibitor currently in clinical trials, decreased the phosphorylation of MERTK and downstream signaling in a dose-dependent manner in A673 and TC106 cells and provided potent anti-tumor activity against all five EWS cell lines, with IC50 values ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11013014	IR (neat): ν = 3432 (NH), 1667 (C=O Ketone), 1652 (C=O Amide), cm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11066331	Altogether, the intact cell MALDI TOF MS coupled with suitable mathematical apparatus represents a low-cost, robust simple, and straightforward method that allows discrimination of individual cell types, either alone or in mixtures or even the individual cell states during differentiation or acquisition of abnormal phe...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11790599	Phase-contrast images showing effects on cytoplasmic vacuolization of SK-BR-3_LR600 cells following treatment of TSL (6.32 μM, 24 h) and lapatinib (600 nM, 24 h) (20×).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9509578	These natural compounds were established as potential candidates with no toxicity but did not succeed due to minimal solubility and bioavailability, hampering their efficacy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10174970	To date, more than 60 pancreatic cancer cell lines have been reported.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "date", ",", "more", "than", "60", "pancreatic", "cancer", "cell...
PMC11045125	In comparison to uninfected BLs, EBV-infected BLs contain fewer cellular mutations in genes involved in apoptosis , suggesting that latent EBV infection provides an essential survival advantage to EBV+ BLs by inhibiting Myc-induced apoptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11529598	B. Migration ability of miR-3154 sponge A172 cells and control A172 cells was measured using Transwell assay. *	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "B.", "Migration", "ability", ...
PMC11675244	Meanwhile, Dickkopf (DKK) proteins bind to LRP5/6, preventing the formation of the Wnt/Frizzled/LRP5/6 complex and halting Wnt signaling .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Meanwhile", ...
PMC9646302	JNK, p38, and ERK are important components of the MAPK pathway .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "JNK", ",", "p38", ",", "and", "ERK", "are", "important", "components"...
PMC11463018	White solid, 77.3% yield.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "White", "solid", ",", "77.3", "%", "yield", "." ] } ]
PMC11703992	The proportions of apoptotic cells in Blank-PMA and DDIT4-OE-PMA induced Jurkat cells were evaluated by flow cytometry, which revealed that DDIT4 overexpression inhibited the apoptosis of PMA induced Jurkat cells (Fig. 8J, S9A–C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11739484	RT-qPCR-based expression of MMP7 in Ctrl-A375 cells compared to si-MMP7-A375 cells. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RT-qPCR-based", "expression", "of", "MMP7", "in", "Ctrl-A375", "cells", "compared", ...
PMC11144200	In addition, we ran a cytokine analysis on the mice’s serum that was collected on day 28.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", "we", ...
PMC8623816	The presence or absence of RsRV5 was confirmed by extracting dsRNA and RT-PCR using specific primers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "presence", "or", "absence", "of", "RsRV5", ...
PMC11190538	Data are expressed as Mean ± SD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "expressed", "as", "Mean", "±", "SD", "." ] } ]
PMC11770199	Four days after injection, mice were treated with normal saline, 2 × 10 mMSCs-GFP, and 2 × 10 mMSCs-p14.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Four", "days...
PMC8806312	The association between T cells CD4 memory activated and overall survival of OS Evaluation of the proportions of TIICs based on CIBERSORT. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC6771295	Values are normalized to actin and then to control.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Values", "are", "normalized", "to", "actin", "and", "then", "to", "control", "." ] } ]
PMC9429973	Aims: To compare the frequently used CD138 immunohistochemistry- based method of plasma cell quantitation, to a proposed new method, using interobserver and intraobserver concordance parameters.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: The primary objective of this study was to evaluate the odds of developing non-hematological malignancies and cancer types in iMCD patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ...
PMC11562028	Reverse transcription and quantitative real-time polymerase chain reaction were performed using the high-capacity reverse transcription kit and the SYBR Green, according to the instructions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	Participants were recruited from 9 provinces and 1 municipality.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Participants", "were", "recruited", "from", "9", "provinces", "and", "1", "municipality", "." ] } ]
PMC11391695	10% fetal bovine serum (FBS, Lonsera, USA) was added to each cell in a humidified environment with 5% CO2 and 37 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11775197

Fenofibrate also reduces cancer cells’ invasion and migration ability .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fenofibrate", "also", "reduces", "cancer", "cells", "’", "invasion", "and", "migration", "abilit...

PMC8864075

In summary, reTFAE can inhibit the PI3K/Akt pathway with the core of TWIST1, thereby inhibiting the glycolytic pathway to suppress EMT in A549 cells (Figure 5).

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PMC11534377

FOXO3, involved in apoptosis and cell cycle regulation, displayed a notable increase in expression in the treated cells (P = 0.0008), suggesting an enhanced pro-apoptotic response.

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PMC11791203

Early apoptotic cells were characterized by green fluorescence, while late apoptotic or necrotic cells exhibited red fluorescence.

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PMC11727638

The downregulation of CD20 was also observed on KML-1 cells cultured in the Cell Dome, where CD20 expression was gradually downregulated with increasing culture periods.

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PMC11576293

The signal transduction of EGFR tyrosine kinase is strongly linked to tumor progression.

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PMC9429973

Image: Summary/Conclusion: This analysis reveals that pts across all PKLR genotypes experienced a wide range of serious comorbidities/complications across multiple systems.

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PMC11703992

CD40LG and IL16-CD4 L-R pairs maintain inflammation response by enhancing the activation of APCs and the production of pro-inflammatory cytokines.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CD40LG", "and", "IL16-CD4", ...

PMC11298021

Then, 100 µL of dimethyl sulfoxide (DMSO, Sigma, USA) was added to dissolve the formazan crystals.

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PMC6379402

We do this by clustering genes in different networks and by computing the enrichment of the clusters in biological annotations (see details in Methods, section Enrichment-based measures).

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PMC9545474

High‐resolution ESI‐MS was obtained for complexes 4–8 and confirmed the proposed structures (Figures S18–S22).

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PMC11194678

Data were collected from three independent batches of cultures.

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PMC11541241

The plant‐derived compound antofine could be another inhibitor to dissect the TOR signalling function and may be used as a biofungicide to control plant fungal disease.

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PMC9622879

It also helps to increase the benefits for prosumers because the pricing proposed by the LEM is usually better than that of the electricity provider.

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PMC10969097

The study involved 40 patients divided into two groups, with one group (n = 19) receiving the Andosan™ extract and the other group (n = 21) receiving a placebo, both in conjunction with chemotherapy.

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PMC9429973

GOFC demonstrated a low correlation with predictive accuracy; thus, limited weight should be assigned to GOFC when selecting the optimal survival model in LBCL.

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PMC11129910

These RAB25-downregulated cell lines became the model for our study.

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PMC9429973

Image: Summary/Conclusion: ARI0002h is the first European academic CART for RRMM that has demonstrated deep and durable responses and a favorable safety profile, including the absence of neurotoxicity and the feasibility of a second booster dose.

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PMC11012012

The effects of SLAMF7/CD319 on B cell proliferation were shown on both naive and memory B cells.

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PMC11297139

The representative images supported by the relevant statistics have been chosen upon three independent preparations with similar outcomes.

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PMC11792766

Ethanol as such seems to interfere with the function of the NRU assay.

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PMC7185206

Similar results were seen in the MB-MDA-231 breast cancer cell line (Supplemental Figure 6a).

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PMC11469524

While such models help to gain the understanding of pathway interactions, they are not suitable for simulations or quantitative model comparisons.

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PMC11477621

C NMR (100 MHz, CDCl3) δ 188.3, 173.9, 130.3, 130.1, 120.4, 108.0, 60.3, 49.8, 34.3, 31.4, 28.8, 27.5, 26.4, 24.9, 14.4.

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PMC11748618

Antiretroviral therapy has greatly improved the quality of life of people living with HIV and limited the spread of the virus, but the accumulation of escape mutations may threaten the long-term use of ART.

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PMC7602170

The eIF4F complex consists of three polypeptides (eIF4E, eIF4A and eIF4G).

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PMC11747467

A trial involving 23 metastatic breast cancer patients treated with ART reported nonsevere ART-related adverse events affecting the auditory system (46, 47).

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PMC3681794

B, 48 hours after exposure to a 1 hour pulse of doxorubicin (10 µM), etoposide (500 µM) or cisplatin (75 µM) in normoxia or hypoxia U2OS cells were stained with DAPI and morphologically apoptotic cells counted with a fluorescent microscope.

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PMC11670407

The values are expressed as means ± S.D.s. *

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PMC11697065

Viable cell density and cell viability were assessed using a Vi-Cell XR automated cell counter and viability analyser (Beckman Coulter, High Wycombe, UK).

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PMC11240448

Although 33 different luminal BC cell lines have distinct mutational and expression profiles, the inferred architecture of causal connections of core networks in these cell lines is similar, and oncogenesis is mainly driven by the mTOR pathway.

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PMC9268620

Necrosis, on the other hand, is known as untimely cell death that happens as a consequence of extreme and uncontrollable external factors.

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PMC11750712

In patients with a TRBC1 PTCL, CAR T cells directed against TRBC1 should target the lymphoma, but spare healthy TRBC2 T cells.

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PMC11725127

Two primary strategies to tackle cancers with KRAS mutations involve either the direct inhibition of KRAS activity or the induction of its degradation.

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PMC11222184

Villa et al. showed that the HSP90 inhibitors 17-AAG and Geldanamycin caused a significant inhibition of telomerase activity in JR8 human melanoma cells .

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PMC9429973

In contrast, the RS for patients with isolated adult pLCH at the same time points were 98.3%, 94.8%, 90.9% (Figure).

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PMC11047729

Meanwhile, I3C caused the down-regulation of c-Myc—a transcription factor that regulates the hTERT gene transcription.

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PMC8540692

Contrarily, in another colon carcinoma cell line, HCT-116, NaBu upregulated the expression of these promoters .

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PMC11742431

Immediately afterward, the expression levels of Survivin in pan‐cancer were analyzed.

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PMC11767817

Based on these results, the MK-2206 concentration of 5 μM was selected for further experiments.

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PMC9429973

Results: As of 23 July 2021, the median follow-up among all treated patients in Phase 2 (N=55) was 26.8 months (range, 20.7-32.6).

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PMC9621239

The number of the significant sites which have higher mutation frequencies, located within the transactivation domain or strongly conserved region are displayed in the Venn diagram. (

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PMC9429973

Aims: To describe the multiple-adjudication methodology employed to confirm diagnosis of TA-TMA across adult and pediatric transplant centers.

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PMC9429973

Protein expression analysis of carfilzomib sensitive vs. resistant cell line variants indicate alterations of BCL2 family members (MCL-1, BCL-xL, BCL-2, BAD, BID, BAX, BAK, BIM, NOXA and PUMA) in untreated conditions as well as under carfilzomib treatment (Figure 1).

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PMC11528603

Apoptosis and proliferation–related gene expression at 24-hour time point of treatment. (

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PMC11697703

After IUE at E15 of miR193b, miR-365, both miR193b and miR-365, or scrambled miRNA, we analyzed the presence of heterotopic clusters of neurons that failed to migrate into the superficial layers at P14.

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PMC9429973

Informed consent was obtained from all participants.

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PMC11406030

The MTT assay was used to determine cytotoxicity after treatment.

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PMC11394730

Quercetin also decreased the potential of the mitochondrial membrane in malignant glioma cells U373MG.

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PMC5034105

A ⩾2 log increase in mean viral load with ZIKV-NS1 protein expression and CPE were observed in the nonhuman primate (Vero and LLC-MK2), pig (PK-15), rabbit (RK-13), hamster (BHK21) and chicken (DF-1) cell lines.

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PMC8303372

The optical density (OD) of the solutions in each well was determined using an automatic microplate photometer (ELx800; BioTek, Bad Friedrichshall, Germany) at a wavelength of 570 nm.

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PMC5963610

The pain, skin rash and sequential computed tomography (TAC) from tumors, life´s condition and disease were analyzed during 15 years.

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PMC11742290

High expression of LGR5 in ovarian cancer cells was associated with carboplatin, cisplatin, and taxol resistance.

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PMC9351137

These results suggested that the mitotic localizations of the CRS reflect intrinsic properties of the proteins, independently of the cell type.

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PMC8382973

The primary physicochemical properties commonly assessed for semisolids include osmolality, viscosity, and pH. Osmolality was measured to determine how the drug deviated from isosmolar (290 mOsmol/kg) conditions.

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PMC11106977

Since its discovery, researchers have demonstrated O-GlcNAcylation on thousands of proteins implicated in numerous different biological processes.

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PMC11078693

Biotium kits can work with both carrier-free and some non-carrier-free antibodies; see manufacturer protocol for details: https://biotium.com/wp-content/uploads/2017/10/PI-Mix-n-Stain-Antibody-Labeling-Kits.pdf.

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PMC11411004

The degree of histone acetylation can be regulated by HDACis, and transgene expression in recombinant CHO monoclonal antibodies can be enhanced after treatment with NaBu HDACi (Nmagu et al. 2021).

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PMC10154881

Accumulation of tumor antigen‐specific CTLs induced by rMV‐SLAMblind cancer therapy. (

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PMC9370419

The human hepatoma Huh7 cell line and HepG2-derived 2.2.15 cell line (constitutively producing HBV Dane particles) were kindly provided by the Cell Bank, Chinese Academy of Sciences (Shanghai, China).

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PMC11711063

The increased occupancy by ARID1A and reduced H3K27 acetylation at the proximal regulatory region of the ZG16B gene were confirmed by qPCR (Figure 1B,C).

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PMC9429973

1% pts discontinued due to TEAEs.

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PMC8735881

As expected, two mutants, CMI02/P41m and CMI06/P41m, were well expressed on the surface of transduced TZM-bl and 293FTTarget cells without affecting the HIV receptor and coreceptors either (Fig. S6); however, they exhibited similar activities with GPI-10E8 in inhibiting the infections of HIV-1 SF162 and SIV mac239 (Fig...

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PMC11535726

Unlike K.crustacea, K.longirostrata has cylindrical, proliferating conidiogenous cells and obpyriform to obclavate conidia, with longer (15–100(–120) × 2.5–6 μm), guttulate, proliferating rostrate structures and a mucilaginous sheath surrounding the upper part of the apex.

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PMC5173112

To examine the cell invasion, 1 × 10 siRNA-transfected cells were plated on Matrigel invasion chambers (Corning, NY, USA).

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PMC11766309

The highest and lowest risk effects were found for the KICH (HR = 6.964, p=0.026) and HNSC (HR=1.337, p=0.013) cancers, respectively.

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PMC9429973

Of those, only 3 (5%) and 1 (2%) harbored NPM1 and FLT3-ITD mutations, respectively.

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PMC9024365

Quantification indicates no significant increase in the mean area of clusters after the 4C incubation (Figure 7B).

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PMC11786704

Defective diabetic wound healing is a major clinical challenge, where hyperglycemia at the wound site induces excessive reactive oxygen species (ROS) which activate the MAPK pathway (particularly p38 MAPK), resulting in sustained release of inflammatory factors and cellular damage/apoptosis.

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PMC11770199

Eight hours after transfection, human MSCs-tet-p14 were digested and mixed with melanoma cells A375 and MV3 expressed with GFP protein, respectively.

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PMC11705630

Statistical analysis was conducted using Student's t-test or one-way ANOVA for more than two groups.

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PMC11731161

We analyzed the subcellular localization of RanBP1 following blocking XPO1 degradation by MG132.

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PMC11700165

2Phosphorylation and inhibition mechanisms of SYK fusion kinases. (

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PMC10965680

Identification of selective signals in Xiangdong goats.

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PMC11740207

By comparing these datasets with scRNA-seq results from morula, blastula, gastrula and VSELSC and/or VSLSLC stages, researchers can identify both shared and unique molecular signatures among these cell groups.

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PMC11680049

For explants placed on WPM, primary callus formation was primarily characterized on the leaf blade, predominantly in the mesophyll area near the midrib, while for explants placed on MS medium, it was noted on the stem in the internodes and meristems (Figure 4a,b).

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PMC11352666

Treatment with MRX-2843, a first-in-class, MERTK-selective tyrosine kinase inhibitor currently in clinical trials, decreased the phosphorylation of MERTK and downstream signaling in a dose-dependent manner in A673 and TC106 cells and provided potent anti-tumor activity against all five EWS cell lines, with IC50 values ...

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PMC11013014

IR (neat): ν = 3432 (NH), 1667 (C=O Ketone), 1652 (C=O Amide), cm.

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PMC11066331

Altogether, the intact cell MALDI TOF MS coupled with suitable mathematical apparatus represents a low-cost, robust simple, and straightforward method that allows discrimination of individual cell types, either alone or in mixtures or even the individual cell states during differentiation or acquisition of abnormal phe...

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PMC11790599

Phase-contrast images showing effects on cytoplasmic vacuolization of SK-BR-3_LR600 cells following treatment of TSL (6.32 μM, 24 h) and lapatinib (600 nM, 24 h) (20×).

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PMC9509578

These natural compounds were established as potential candidates with no toxicity but did not succeed due to minimal solubility and bioavailability, hampering their efficacy.

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PMC10174970

To date, more than 60 pancreatic cancer cell lines have been reported.

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PMC11045125

In comparison to uninfected BLs, EBV-infected BLs contain fewer cellular mutations in genes involved in apoptosis , suggesting that latent EBV infection provides an essential survival advantage to EBV+ BLs by inhibiting Myc-induced apoptosis.

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PMC11529598

B. Migration ability of miR-3154 sponge A172 cells and control A172 cells was measured using Transwell assay. *

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PMC11675244

Meanwhile, Dickkopf (DKK) proteins bind to LRP5/6, preventing the formation of the Wnt/Frizzled/LRP5/6 complex and halting Wnt signaling .

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PMC9646302

JNK, p38, and ERK are important components of the MAPK pathway .

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PMC11463018

White solid, 77.3% yield.

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PMC11703992

The proportions of apoptotic cells in Blank-PMA and DDIT4-OE-PMA induced Jurkat cells were evaluated by flow cytometry, which revealed that DDIT4 overexpression inhibited the apoptosis of PMA induced Jurkat cells (Fig. 8J, S9A–C).

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PMC11739484

RT-qPCR-based expression of MMP7 in Ctrl-A375 cells compared to si-MMP7-A375 cells. (

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PMC11144200

In addition, we ran a cytokine analysis on the mice’s serum that was collected on day 28.

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PMC8623816

The presence or absence of RsRV5 was confirmed by extracting dsRNA and RT-PCR using specific primers.

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PMC11190538

Data are expressed as Mean ± SD.

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PMC11770199

Four days after injection, mice were treated with normal saline, 2 × 10 mMSCs-GFP, and 2 × 10 mMSCs-p14.

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PMC8806312

The association between T cells CD4 memory activated and overall survival of OS Evaluation of the proportions of TIICs based on CIBERSORT. (

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PMC6771295

Values are normalized to actin and then to control.

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PMC9429973

Aims: To compare the frequently used CD138 immunohistochemistry- based method of plasma cell quantitation, to a proposed new method, using interobserver and intraobserver concordance parameters.

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PMC9429973

Aims: The primary objective of this study was to evaluate the odds of developing non-hematological malignancies and cancer types in iMCD patients.

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PMC11562028

Reverse transcription and quantitative real-time polymerase chain reaction were performed using the high-capacity reverse transcription kit and the SYBR Green, according to the instructions.

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PMC9429973

Participants were recruited from 9 provinces and 1 municipality.

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PMC11391695

10% fetal bovine serum (FBS, Lonsera, USA) was added to each cell in a humidified environment with 5% CO2 and 37 °C.

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