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BioData-CellLine_annotated

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PMC9688728
Abnormalities in protein synthesis quantity and quality of are often associated with various cancers , including hepatomas.
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PMC10933092
p-values for every result are labeled in the figures, and p < 0.05 was considered significantly different.
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PMC11185260
p<0.05. (
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PMC11476666
To further probe the effect of the molecules on stemness features, A549 cells grown in 3D cultures as spheroids were treated for 24 h, with stilbenes added either at the time of cell seeding (‘preformation’) or on day 3, once spheroids were already visible in culture (‘postformation’).
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PMC11247842
Therefore, large differences in allele frequencies at the QTL are expected both as a result of artificial selection and genetic drift.
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PMC11518702
The discovery of HGAL as a DLBCL marker (1, 2, 10, 17) and disease severity index (OS) (6, 58, 59) prompted studies of HGAL’s expression profiles and gene regulation.
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PMC10366908
To determine the KD of EMab-300 with mEGFR-expressing cells, we conducted kinetic analyses by flow cytometry using CHO/mEGFR and NMuMG cells.
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PMC10965680
The considerable distance between Xiangdong goats and Jining goats signifies a greater degree of differentiation between them.
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PMC8068766
Meanwhile, HepG2-2.2.15 cells were able to grow under both conditions.
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PMC9341513
Typical snapshots of the gene and a 5-kbp flanking region on each side.
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PMC9429973
In the process of imaging flowcytometric analysis, we sorted CD138-positive cell fraction, computed the distance between FISH probes using originally developed spot counting tool, and determined to be positive for translocation when the distance is under the threshold.
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PMC11742670
In SMILES notation, bonds between atoms are indicated by special characters.
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PMC10391797
Several publications have demonstrated that selective HDACi can influence tumor immunogenicity, the microenvironment, and the functional activity of specific immune cells.
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PMC7582629
In general, the comparison of Raman spectra between normal versus cancer cells have shown differences in the concentration of biochemical compounds of lipids, nucleic acids and proteins.
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PMC11769516
Nearly 29 structural analogues of these cyclic hexadepsipeptides have been described .
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PMC11470381
Figure 3.Mapping out cell ROIs.
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PMC10237474
All DNA constructs were sequence-verified prior to transfection.
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PMC10656496
We do not currently knowingly take advantage of intratumoral competition, do not design studies to prevent emergence of resistant clones, nor have a good understanding of how individual agents affect subpopulations of tumors.
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PMC11361748
More generally, our findings add evidence linking all subclasses of IFs to the regulation of cellular kinases with direct significance for several cellular processes.
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PMC11541409
Other drug resistance mechanisms for KIT/PDGFRA-mutant GISTs have also been identified.
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PMC11684297
Figure 1h highlights the characteristic d-spacing of approximately 0.2 nm, as indicated by the arrows.
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PMC11380454
These data collectively suggest that by inhibiting PD-L1 expression, SAS enables CTLs to induce malignant cell death.
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PMC11506670
The percentage of the open wound area was analyzed using the TScratch software for automated analysis of monolayer wound healing assays .
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PMC11694066
In the latter, 6/19 (32%) and 9/19 (47%) patients showed partial response and stable disease as the best response, respectively.
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PMC11021472
H–I) The effect of circZDHHC11 knockdown on growth of the monoclonal NTCR1CR2 and miR-150BSdel cell lines cells (sh1: light red, sh2: dark red, NT1: black, NT2: grey).
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PMC10969097
As a result, PC3 cells treated with MPSSS reacquire sensitivity to docetaxel.
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PMC11707577
The synthetic process generated a monodispersed, uniformly sized 1D‐TNP, namely M13EGFR(TNP), that fully maintains the morphological characteristics of the template phage.
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PMC10607604
PTPN13 downregulation also increases PC3 cell (prostate cancer) invasion through the Matrigel-coated membrane and upregulates invasion-related genes .
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PMC11711871
The vasoconstriction induced by KCl or Phe was expressed as gram of induced tension.
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PMC10362265
The analysis also included two computed complex models adopting a helical structure for the surface epitope.
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PMC9817179
Whereas PFA fixation in the absence of additional glycine enhances the LLPS appearance (Figure 2B, Figure 4A), in the presence of 25 mM glycine, fixation causes many of the smaller puncta formed in live cells to disappear completely and larger, preformed puncta to turn into a ‘donut’ shape, with the outline of the punc...
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PMC11640476
The uncertainty due to the pipetting error of reading volume was the same as 2D.
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PMC9985266
In this research, we used BLM to construct a PF mouse model, and MRC-5 cells stimulated by transforming growth factor-β1 (TGF-β1) were used to construct a PF model in vitro.
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PMC10957991
Cellular forces are crucial for the maintenance of epithelial cell–cell junctions and in this way epithelial integrity.
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PMC9429973
Summary/Conclusion: We provide evidence that treatment with ATG has an initial negative impact on the CP of HSC from HD and AA pts, likely mediated through acute release of IFN-γ.
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PMC6222726
They found that all lignans affected Giardia adhesion, but only compounds 14, 19, and 20 caused growth inhibition.
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PMC11653533
However, the Curtain fig is an evergreen tree that comes to 15 m (50ft) or more in tallness, with an adjusted thick crown, smooth grey bark, milky sap, and long, lean, dangling ethereal roots (Ravichandra and Paarakh, 2011).
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PMC11628309
In this context, studies have focused on α-synuclein.
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PMC10831439
First, the addition of nivolumab increased the activation and proliferation of alloreactive T cells in the absence of (CAR)-iNKT cells.
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PMC10723784
The majority of cases are diagnosed at stage 4.
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PMC6799808
Cell proliferation and cell division are closely associated with cell cycle progression.
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PMC11740573
It is well known that treatment with anti-inflammatory agents modulates inflammation by suppressing the immune response .
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PMC11453690
Caution should be used to ensure local control of the cancer has been achieved prior to reconstruction.
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PMC11676674
This study was performed to determine genotoxic and antigenotoxic effects of C. monspeliensis leaf extract against mitomycin C (MMC) using an in vitro cytokinesis-block micronucleus assay (CBMN) in the Chinese Hamster Ovarian K1 (CHO-K1) cell line.
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PMC8540611
In the future, other important properties of gold nanoparticles need to be explored, e.g., the effect of surface plasmon resonance.
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PMC9429973
Further work-up revealed an aberrant karyotype (47,XY,+11/ 46,XY,der(7)t(7;11)(q31;q12)/ 46,XY), a partial tandem duplication of KMT2A (KMT2A-PTD) as well as variants in IDH2, DNMT3A and NRAS (Figure 1.) (
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PMC9429973
Description of Cohort: Patients were treated either with combination of AZA-VTX or LD-AraC-VTX.
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PMC11666785
As a result, correlation between subsequent frames help recognise consistent emission from fortunate molecules.
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PMC11655536
To further confirm the inhibition effect, immunohistochemistry was performed to detect the proliferation of MM tumor cells.
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PMC11535726
This genus was initially accommodated in Pleosporaceae by Hawksworth (1985) and Barr (1987), but later transferred to Pleomassariaceae by Barr (1993), based on morphological data.
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PMC11298021
Similarly, miR-3143, miR-3182, and rapamycin group significantly induced cell cycle arrest at the G0/G1 phase (*P < 0.05).
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PMC9776316
Our study reveals that the XRCC4 in the NHEJ pathway contributes to platinum resistance by reducing DNA damage and provides preclinical evidence for targeting XRCC4 as a new strategy to overcome cisplatin resistance in ovarian cancer treatment.
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PMC11775197
MYC promotes the interaction between LEF1 and β-catenin by directly targeting LEF1, activating the expression of PPARβ/δ and Acyl CoA dehydrogenase 9(ACAD9).
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PMC10818573
TwistDx published a study on RPA technology in 2018 that contains detailed kit components and can provide a reference for subsequent experimental component adjustment so that the RPA amplification phase and nfo probe digestion phase do not interfere with each other and react simultaneously.
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PMC10362265
The movement of the helix/loop is shown in the second column.
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PMC11706776
C Overall survival probability (Kaplan Meier curve) of ES patients according to KCNN1 expression (high or low).
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PMC10551595
Taking together, GinA may be considered a proper supplement in T‐ALL combined chemotherapy to overcome resistance to Dexa.
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PMC9429973
Response was assessed by the investigator according to the Lugano Classification Revised Staging System (Cheson 2014).
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PMC11495567
The inserts containing cell suspensions were placed into the wells with medium containing 10% FBS.
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PMC11693599
These results suggest that primary ovarian cancer cells secrete EVs enriched with CD109.
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PMC10728200
In conclusion, IM could induce ferroptosis in GIST cells.
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PMC10988555
A possible explanation is that the UV–vis spectrum for complex 4 is blue-shifted, hence, the 339 nm band should correspond to the MLCT transition calculated at 459 nm (see Table S2).
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PMC8592717
It showed inhibitory effects against angiogenesis by increasing CD31 and GPER-1 and decreasing VCAM-1 and CD40 expression aortic ring assay in rats .
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PMC9429973
Our comparison between the group of PRHL and non-PRHL patients in terms of age, sex, time to consultation, performance status (PS) score, clinical signs at admission, histological subtype, presence of Bulky mass on chest X-ray, the Ann Arbor stage and the prognostic risk group did not show any significant difference, w...
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PMC11045125
This process utilized gencode v38 comprehensive gene annotations and GenBank AG876 annotation (accession number NC_009334), incorporating parameters—estimate-rspd and—strandedness reverse.
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PMC6461034
Different kinase ranking approaches have been described previously.
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PMC11093197
These reports suggest that the activation of RAS may antagonize RB1 LOF‐induced carcinogenesis.
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PMC11543853
However, particles of rhinovirus 2 were released into the cytoplasm in bafilomycin A1-treated cells (Fig. 4d), and the odds of their genome release into the cytoplasm were only reduced 2-fold relative to the untreated cells (Fig. 4de).
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PMC11683240
Just prior to imaging, cells were covered in 97% 2,2′-thiodiethanol.
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PMC9429973
Our data are particularly interesting because in the pivotal ALFA0701 study, only one patient underwent Autologous-SCT, but in the control arm.
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PMC11352877
Hypoxia deepens the influence of VEGF-A (as the downstream target of HIF-1α’s action is VEGF-A).
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PMC11764090
Furthermore, the protective mechanisms against DNA damage in root stem cells induced by low-temperature stress involves the crosstalk of IAA and CTK.
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PMC11766350
Genetic diseases caused by missing or defective genes can be treated by transferring a wild-type copy of the affected gene into a patient’s cells.
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PMC10237474
Error (ppm) for the full-length protein was calculated with the following equation: The unit of Observed mass and Theoretical mass is Da.
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PMC11323699
Statistical significance is indicated as ns (not significant) or *p < 0.05 (one-tailed Mann–Whitney test) In ovarian carcinogenesis, the matrix glycoprotein TSP-1 plays a significant role as a primary ligand interacting with CD47 (Fig. 4a, left panel).
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PMC11201989
First, we found that depletion of PD-L1 with siRNA increased the intensity of Ift20 at the Golgi (Figure 3A,B).
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PMC9429973
Aims: The aim of this study was to profile Clever-1 expression in AML and MDS and to test in preclinical models bexmarilimab’s growth inhibitory and immunomodulatory potential, as a single agent and in combination with azaciditine and venetoclax.
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PMC9739791
The main focus of this review is an investigation of biological activity and Pt(IV) prodrugs photoreduction mechanisms.
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PMC11535726
In the meantime, Wijayawardene et al. (2014) suggested using K.atra to replace K.aethiops as the type species of Kirschsteiniothelia.
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PMC11627133
Subsequently, we imaged the endogenous EGFR in fixed A431 cells using J18‐RhoBAST and SpyRho with the RhoBAST‐PAINT approach achieving a comparable localization precision and resolution (26 nm, 67 nm, respectively.
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PMC7841189
Short hairpin RNA (shRNA) targeting LTBP2 (sh-LTBP2) and nontargeting control (mock) were designed and synthesized by GeneChem (Shanghai, P.R. China).
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PMC11348300
This results in oxygen measurements that occur in a space where oxygen consumption is not as rapid as intracellularly and where resupply is faster due to the convection of oxygenated blood.
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PMC9844987
Supporting this hypothesis, we observed that low variable promoters were highly enriched with basic cellular housekeeping processes, in particular metabolic processes (Figure 3A).
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PMC10957991
Examples on representative epithelial sheets, analysed with the software.
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PMC9429973
Moreover, complex interactions between TKIs and NK cell function have been discovered in CML.
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PMC11568601
p < 0.05, **p < 0.01, vs. the control group In present research, RNA-seq was conducted on osteosarcoma 143B cells to screen the genes affected by TGT that were involved in the process of apoptosis.
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PMC11247842
Although we included the regulator element annotation from eight tissues and large-scale eQTL mapping from farmGTEx , we still had limited information to interpret these variants and important regulatory elements could be hidden among.
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PMC11754784
5Kinetic analysis of signal leakage of DNA computation in complex cell mixtures.a Reaction pathways of DNP3-based computation in the present of target cell and two kinds of by-standing cells.
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PMC11310713
These indicated that treatment of the GTB constructs prevented weight gain after OVX, such as accumulation of fat caused by sex hormone deficit.
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PMC9000591
Most notably, cancer treatments are complicated by the toxic side effects of drugs associated with oxidative stress.
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PMC11461833
The upregulated (C) or downregulated (D) DEGs in the gSTXBP5 (STXBP5 guide3) group compared with the gAAVS1 group of HA-progerin-expressing HEK293 cells were identified through GO term and KEGG pathway enrichment analysis. (
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PMC11594806
In their study, adding diclofenac—a non-steroidal anti-inflammatory drug—showed greater effectiveness against PDAC metastasis than CD73-blocking antibodies and enhanced GEM’s therapeutic effects in a spontaneous KPC (LSL-KrasG12D/+, LSL-Trp53R172H/+, and Pdx-1-Cre) pancreatic cancer model .
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PMC9429973
T.-D. Tan, L.-W. Chiou, H.-C. Kau Hematology and Medical Oncology; Ophthalmology, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan Background: Marginal zone B cell lymphoma (MZBCL) is one of indolent B cell lymphoma including nodal, extra-nodal, and splenic types.
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PMC5415764
The disulfide-containing PLGA-SS-PTX conjugate was synthesized through an esterification reaction between PTX and the terminal carboxyl in PLGA-DTPA using DCC and DMAP as catalysts.
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PMC10745221
PRMT3, 6, and 7 are differentially expressed depending on the stage of the cell cycle in synchronized HeLa cells .
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PMC11657695
The regulation of the Hippo signalling pathway by KCNA2 was studied by measuring Hippo/YAP target genes expression, while YAP protein expression was studied with Western-Blot and immunofluorescence approaches.
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PMC10978090
In anticipation of surgery in this HIT patient on VA-FF-ECMO with therapeutic dose of anticoagulation, a multidisciplinary team discussed the intraoperative need of a cell saver involving a bolus of UFH and the associated risk of reaction with HIT antibodies.
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PMC9429973
Aims: In this study, we analyzed the clinical characteristics of 148 FA children from 20 provinces in China from October 2003 to October 2021.
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PMC10656496
Solid tumors like osteosarcoma are more complex and dynamic than we appreciate clinically with fixed chemotherapy plans.
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PMC10530622
Moreover, the endogenous production of oxalate happens mainly in the liver and accounts for around 90% of oxalate eliminated in urine .
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