OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11267830	Among the numerous downstream effector changes induced by indisulam, our database search revealed that the survival of the Jurkat cell line is highly dependent on the THOC1 gene.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", ...
PMC10443665	Each extract concentration was assayed in 4 wells and repeated 3 times.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", "extract", "concentration", "was", "assayed", "in", "4", "wells", "and", ...
PMC11476222	LC-MS combines the high separation power of liquid chromatography with the sensitivity and accuracy of mass spectrometry to separate, detect, and identify a wide range of compounds in a sample .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10999934	1Cell annotation and identification of malignant cells in the GSE158937 dataset. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "1Cell", "annotation", "and", "identification", "of", "malignant", "cells", "in", ...
PMC10329237	However, despite the promising anti-fibrotic effect of pirfenidone, its toleration by patients in full doses is low (10).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",...
PMC11538390	Examination of allele frequencies and LD patterns suggested multiple independent signals in the region covering the IRF6 gene (Fig. 2b).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Examination", ...
PMC9429973	Quantitative reel time PCR (quantification of AID, cMYC and IgH locus transcripts).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Quantitative", "reel", "time", "PCR", "(", "quantification", ...
PMC9878562	Collective migration has been extensively studied to describe the metastasis of solid tumors but is seldom used to describe the movement of hematological cancers in a contact independent manner.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11261875	Moreover, imatinib-resistant GIST 882 cells were more vulnerable to glycolysis inhibition than GIST 882 cells, whereas imatinib-resistant GIST-T1 cells were more resistant to OXPHOS inhibition than GIST-T1 cells .	[ { "tags": [ "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", ...
PMC11045125	D. EBV+ Akata BL cells were infected with a lentivirus vector expressing LMP1 or a control lentivirus and two days later cells were treated with puromycin for 3 days.	[ { "tags": [ "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11534035	In this work we aimed to uncover the role PAI1 plays in the proliferation, migration, and invasion of vulvar cancer (VC), and define the protein’s function as an oncogene or tumor suppressor.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10671321	Appropriated Alexa fluorescent secondary antibodies (Invitrogen, Waltham, MA, USA, 1:1000) and Hoechst (5 μg/mL) were added for 1 h. Image acquisitions were performed on the spinning disk confocal (Zeiss®, Jena, Germany) with the 63X objective and CellInsight High content CX7 system (ThermoFisher, Waltham, MA, USA) wit...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10329074	As shown in Fig. 5C-D, consistently, siYBX3-3 group cells showed significantly decreased proliferation and clone formation, ***P < 0.001.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10734950	Following resuspension in 500 μl PBS, the cells were given a 30 min recovery period and then analyzed by the flow cytometer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Followi...
PMC7841189	Furthermore, CCK-8 analysis showed that cell proliferation was significantly suppressed in sh-LTBP2-transfected FTC133 cells compared with the mock-transfected control group (Fig. 2C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC11774251	TNF-α-stimulated HaCaT cells led to a significant reduction in K1 expression and increased levels of K6 and K17 compared to the NC group.	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	By engaging innate-like T cell subsets with inherent antitumor activity, namely Vγ9Vδ2-T and type 1 NKT cells, LAVA-051 has the potential to combine high therapeutic efficacy with limited off-tumor toxicity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11291490	As dusCD40L has a high sequence identity among birds (Supplementary Fig. 1), its ability to promote the proliferation of duck PBMCs (duPBMCs) and chicken PBMCs (chPBMCs) was detected in the present study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11611077	Since Qmax indicates the total amount of charge carried by all prestin in the cell membrane and e is the electron charge, which is presumed to equal the charge carried by one prestin molecule, the number of prestin molecules in the cell is given by Qmax/e.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Plasma cell content ranged according to myelogram from 1 to 89% (Me 26%), paraprotein secretion was 0.1 to 85 g/L, Bens-Jones protein in urine (from trace values to 12.54 g/day) was determined in 54 patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11525028	N-labeled Asn amount in ASNS-KO and control cell lines (n = 3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "N-labeled", "Asn", "amount", "in", "ASNS-KO", "and", "control", ...
PMC11291490	Conversely, prominent Th2 cytokines, IL-6 and IL-10, play a pivotal role in supporting B cell responses.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Conversely", ",", "prominent", "T...
PMC11473843	Scheme of the in vivo experiment workflow.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scheme", "of", "the", "in", "vivo", "experiment", "workflow", "." ] } ]
PMC11317131	Active phage capable of recombining the AP and CP express gIII and generate progeny containing a functional integrase variant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Active", "phage", "capable", "of"...
PMC5673060	Phosphopeptides were eluted using 2 × 50 μl of 5% NH4OH solution and 1 × 50 μl pyrrolidine.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Phosphopeptides", "were", "eluted", ...
PMC11748335	Consequently, we selected −0.7 as the WScutoff for our analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Consequently", ",", "we", "selected", "−0.7", "as", "the", "WScutoff", "for", "our", ...
PMC11317131	The directed evolution method described here could easily be adapted to further improve these integrases analogous to PhiC31 and Bxb1 integrases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "directed", ...
PMC9429973	Minimal residual disease (MRD) negativity at 10 was assessed by next-generation sequencing.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Minimal", "residual", "disease", "(", "MRD", ")", "negativity", ...
PMC7022782	The particle size of ICG-loaded NPs ranged from 120 to 200 nm and was influenced by the concentration of dye (Table 1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11621493	Representative TLC of acylglycerol levels of control (empty vector transfection) and PLA2G4D-expressing COS7 cells loaded with 300 μM rac-18:1 MAG for 210 min in the absence and presence of DGAT1 and DGAT2 inhibitors (5 μM each). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9325715	bLTF suspension was mixed with 600 mg/L Fe solutions at the ratio 1:1 (v/v) and incubated with stirring for 24 h (T ≈ 23 °C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10530622	The microbiota comprises an enormous collection of microorganisms (viruses, bacteria, archea and eukaryotes) and the majority reside in the GIT.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11740573	After 24 h, 48 h, and 72 h of further incubation at 37 °C under 5% CO2, cell supernatants were collected and analyzed for levels of cytokines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8584666	In recent years, expression of GPI-80 has been found that its expression level may be negatively correlated in survival of cancer patients (The human protein atlas: https://www.proteinatlas.org/ENSG00000112303-VNN2/pathology/renal+cancer; last accessed the link, 6 November 2021).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9712534	Representative images of FRAP analysis of EGFP-TOP2B WT in the presence of ICRF-187.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Representative", "images", "of", "FRAP", "analysis", "of", "EGFP-TOP2B", "W...
PMC11641532	The CCK-8 assay showed enhanced cell proliferation in HSD3B7-overexpressing cells compared to controls at multiple time points (0, 24, 48, 72, and 96 h) (Figure 7C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4839679	Each sample was tested in triplicate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", "sample", "was", "tested", "in", "triplicate", "." ] } ]
PMC11694066	SFs were then used to plot dose–response survival curves, which were generated using three-parameter logistic regression analysis via the drc package in R. Using drc, the AUC values were calculated from the dose–response survival curves.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10999934	The t-SNE plot demonstrated cell types of chemoresistance samples (left) and chemosensitivity samples (right). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "t-SNE", "plot", "demonstra...
PMC9429973	One (2.8%) pt experienced a Gr 5 AE (pneumonia), unrelated to belamaf.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "(", "2.8", "%", ")", "pt"...
PMC11539788	In non-small cell lung cancer (NSCLC), Cheng et al. reported that RNF19A was highly expressed in tumour samples and predicted increased carcinogenesis and poor outcomes in patients with NSCLC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7685376	Figure 3MCM proteins were up-regulated in HCC cell lines and tissues. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Figure", "3MCM", "proteins", "were", "up-regulated", "in", "HCC", "cell", "lines...
PMC11609529	The colony areas were quantified using ImageJ and presented as a percentage of the colony area relative to the corresponding DMSO-treated control groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC11218145	However, the toxicity associated with the in vivo i.p.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "the", "toxicity", "associated", "with", "the", "in", "vivo", "i.p", "." ...
PMC7192625	Upon selection of a feature, a table will also appear below the feature selection drop-down menu with a list of network statistics specific to the selected feature.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10142392	Studies on PCL-based models have shown that drug loading is strongly influenced by the polymer composition and the shape of the nanoparticles . “	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Studies...
PMC11799978	The total protein (20 μg) was used for blotting.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "total", "protein", "(", "20", "μg", ")", "was", "used", "for", "blotting...
PMC9429973	Median age across groups ranged from 65 to 70 y. Baseline clinical characteristics were generally similar across subgroups, but pts with shorter vs longer disease duration were slightly younger with higher blood counts.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4270159	iii.	[ { "tags": [ "O", "O" ], "tokens": [ "iii", "." ] } ]
PMC11185260	RT-qPCR analysis of transcriptional expression of SMARCB1 at indicated time after transfection with either scL-SMARCB1 or scL-vec (N = 4 for BT-12, N = 3 for CHLA-06 and A-204). **	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", ...
PMC9429973	Median age was 72 years and median Charlson comorbidity index was 4 points.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Median", "age", "was", "72", "years", "and", "median", "Charlson", "c...
PMC11612794	The AlphaFold2 predicted structure of human Mis12C in complex with the aa 176–232 region of human CENP-T is similar to the predicted structure of chicken Mis12C in complex with chicken CENP-T (Figures S3F–S3I).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11593084	On-target, off-tumor toxicity is a cause of adverse effects when the target antigen is expressed in normal cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "On-target", ",", "off-tumor", "to...
PMC9429973	This cohort study included patients with and without prevalent hematologic diseases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "cohort", "study", "included", "patients", "with", "and", "without", "prevalent", ...
PMC10723784	In 2017, the FDA approved Olaparib in high‐grade serous ovarian cancer cells independent of BRACA mutations for recurrent ovarian cancer. ,	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "2017",...
PMC11727145	Overall, the novelty and significance of the presented work was the use of optimized methods for DED model setup and the use of patient burn wound exudates in order to obtain an in vitro model with high translational relevance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11746942	The peptide of each sample was desalted on C18 cartridges (Empore™ SPE Cartridges, Sigma), concentrated by vacuum centrifugation, and reconstituted in 10 µl of 0.1% (v/v) formic acid.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10253973	Cytotoxicity and anti-tumor properties can be induced in breast tumor cells by ruthenium complexes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cytotoxicity", "and", "anti-tumor", "properties", "can", "be", "induce...
PMC11680562	The primary cause of cervical cancer is chronic Human Papilloma Virus (HPV) infection, which affects the squamous cells in the cervix.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9024365	Data are represented as mean cluster size ± SEM; n.s.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "represented", "as", "mean", "cluster", "size", "±", "SEM", ";", ...
PMC11539788	Ubiquitin (Ub), a 76-amino acid protein, acts as a linkage site for multiple polyubiquitin chain modifications, which ultimately determine the intracellular function or fate of target proteins .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11200978	Based on the promising results presented herein, studies with other drugs, combinations, doses, etc.,	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Based", "on", "the", "promising",...
PMC9429973	Results: We identified molecular changes in the plasma of B-ALL patients compared to healthy controls.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "We", "identified", "molecular", "chang...
PMC11464982	The production strain is grown as a pure culture using a typical industrial medium in a solid‐state fermentation system with conventional process controls in place.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC8348645	The edible parts of the plants Camellia sinensis, Vitis vinifera and Withania somnifera were extensively used in ancient practices such as Ayurveda, owing to their potent biomedical significance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11320834	In a phase II clinical trial from the GINECO group bevacizumab, olaparib, and durvalumab were tested in advanced ovarian cancer patients with platinum-resistant relapse.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9118379	Or because possible modifications are neglected in the search parameters, spectra of modified peptides can be incorrectly identified as other peptide sequences.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Or", ...
PMC9429973	Patient perceptions of changes in overall health and disease characteristics since diagnosis/disease onset were evaluated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patient", "perceptions", "of", "changes", "in", "overall", ...
PMC5417661	The IC50 value of NOV202 in the A2780 OC cell line was 2, 4 nM and therefore the plasma concentration in the efficacy study, especially at the 40 mg/kg dose, should be high enough for a potent reduction of tumor volumes in vivo, as shown in Figure 6A.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11015054	Subsequently, RNA sequencing was performed to analyze the molecular mechanism of METTL5 in HCC based on the sequencing results, and relevant experiments were performed to verify it.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6133382	While this antibody bound to all of the envelope proteins tested, a small but consistent improvement was observed in binding to the proteins produced in the MGAT1 CHO and HEK 293 GnTI cells compared to the protein produced in the CHO-S cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	There were no differences with age, disease status to HSCT, and prognostic indexs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "were", "no", "differences", "with", "age", ",", ...
PMC10728200	A GIST-T1 and 882 cells were treated with different concentrations of IM for 24 h and the IC50 of IM was determined.	[ { "tags": [ "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "...
PMC11687167	Their results showed that reduced PCSK9 function was associated with accelerated pathogen lipid clearance via LDLR, a decreased inflammatory response, and improved septic shock outcomes .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4355729	The downregulation of PIK3R1 promotes EMT, migration, and cancer stem cell phenotype in renal cancer cells and may contribute to the progression and metastasis of RCC by activating the PI3K/AKT/GSK3β/CTNNB1 pathway.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11509224	Axistatins 1–3 showed inhibition against the murine lymphocytic leukemia P388, pancreatic adenocarcinoma BXPC-3, breast adenocarcinoma MCF-7, CNS glioblastoma SF-268, lung large-cell carcinoma NCI-H460, colon adenocarcinoma KM20L2, and prostate carcinoma DU-145 cell lines, with GI50 values of 19.8, 22.8, and 8.9; 4.8, ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "B-CellLine", "O", "O", "O", "B-CellLine", "O", "O", "O", "B-CellLine", "O", "O", ...
PMC11697703	For differential miRNA expression analysis, neurons in suspension were FACS-purified into RNAlater (Life Technologies) using a FACS Vantage sorter (BD), and purified labeled neuron cell bodies were then frozen at -80°C until RNA purification.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Immunofluorescence showed that BTZ triggered the nuclear translocation of NFATc1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Immunofluorescence", "showed", "that", "BTZ", "triggered", "the", "nuclear", "translocation", "of", ...
PMC11661024	Any distress in microbiota balance can lead to urogenital tract infections, which finally may result in cervical cancer .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Any", "distress", "in", "microbio...
PMC11721295	DAPI was added during the last 5 minutes, and then slides were mounted with Prolong Gold anti-fade reagent (Invitrogen, P36930).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11679892	The experiments were repeated three times to ensure the reliability of the experiments .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "experiments", "were", "repeated", "three", "times", "to", "ensure", ...
PMC8041314	In order to confirm the found results with respect to multitarget ABCB1, ABCC1, and ABCG2 inhibition of compounds 15, 18, 21, 22, and 26 as well as ABCG2 inhibition of compound 27, Hoechst 33342 (ABCB1 and ABCG2), and daunorubicin (ABCC1) fluorescence accumulation assays have been performed as described previously with...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11750165	However, components for Jagged-mediated signaling remain poorly defined during late neurogenesis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "components", "for", "Jagged-mediated", "signaling", "remain", "poorly"...
PMC11787355	D170, P. (2025) https://BioRender.com/z72g103 (b).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "D170", ",", "P.", "(", "2025", ")", "https://BioRender.com/z72g103", "(", "b", ")", "." ...
PMC9429973	Due to the high prevalence of acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the pressure of the transfusion department raised proportionally.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Due", "to", ...
PMC9065483	Representative fluorescence images were captured 24 hpi.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Representative", "fluorescence", "images", "were", "captured", "24", "hpi", "." ] } ]
PMC9429973	RBC-exchange transfusions may also be performed in pts with SCD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RBC-exchange", "transfusions", "may", "also", "be", "performed", "in", "pts", "with", "SCD", ...
PMC11682224	Through an imbalance in the p1-cyclinE-CDK53 pathway in gliomas, CHD1L may cause the G2/S transition.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Through", "an", "imbalance", "in", "the", "p1-cyclinE-...
PMC9429973	Aims: To identify transcriptional and epigenetic characteristics and vulnerabilities of AML MRD, guiding the design of “targeted” combination treatment strategies that successfully eliminate relapse-initiating cells in individual AML patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10040136	The GIST-882 cells that had been treated were then collected.	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "GIST-882", "cells", "that", "had", "been", "treated", "were", "then", "collected...
PMC8193046	Concentration-effect curves of compound 23 (●) against ABCB1 (A), ABCC1 (B), and ABCG2 (C) as obtained in calcein AM (A and B) and pheophorbide A (C) assays, respectively, compared to the reference inhibitors 2 (A;■), 26 (B; ■), and 27 (C; ■) applying ABCB1-overexpressing A2780/ADR (A), ABCC1-overexpressing H69AR (B), ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11763126	A Heatmap of differentially expressed endogenous peptides in ccRCC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "Heatmap", "of", "differentially", "expressed", "endogenous", "peptides", "in", "ccRCC", "." ] } ...
PMC9019892	By comparison, imatinib inhibited only the autophosphorylated KIT and downstream signalling pathways but not ERK, which was due to reactivated FGFR signalling.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11298021	It is noteworthy that the combined treatment with miR-3143, miR-3182, and rapamycin resulted in a greater reduction in the expression levels of the target genes compared to the groups that received rapamycin or any of the miRNAs alone (P<0.0001) (Fig. 7F).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11696576	IC50s calculated by non-linear regression analysis were used as a measure of compound activity for investigating associations with genetic factors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "IC50s", "calculated", "by", ...
PMC7823217	The 3D bioprinted modified constructs were able to form perfusable vasculature within dermal and epidermal skin layers .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "3D", "bioprinted", "modified", "constructs...
PMC11271800	PD-1/PD-L1 expression alone or in combination induces M2 TAM polarization to weaken tumor-specific immunity and promote tumor progression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PD-1/PD-L1", "expression", "alone", "or", ...
PMC8193813	All sensors were calibrated before each sampling day under local ambient conditions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "sensors", "were", "calibrated", "before", "each", "sampling", "day", "und...
PMC8922418	Moreover, Ji et al. used dCas9-SunTag-VP64 to target the HIV-1 LTR region and effectively reactivate the provirus in C11 and A10.6 latent cells (Ji et al., 2016).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11706776	The mechanisms by which potassium channels regulate cell proliferation are the subject of three consensus theories : (1) oscillation of the membrane potential that participates in the control of cell volume and thus allows cells to pass the “cell volume checkpoint” for successful cell cycle progression, (2) potassium e...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11267830

Among the numerous downstream effector changes induced by indisulam, our database search revealed that the survival of the Jurkat cell line is highly dependent on the THOC1 gene.

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PMC10443665

Each extract concentration was assayed in 4 wells and repeated 3 times.

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PMC11476222

LC-MS combines the high separation power of liquid chromatography with the sensitivity and accuracy of mass spectrometry to separate, detect, and identify a wide range of compounds in a sample .

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PMC10999934

1Cell annotation and identification of malignant cells in the GSE158937 dataset. (

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PMC10329237

However, despite the promising anti-fibrotic effect of pirfenidone, its toleration by patients in full doses is low (10).

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PMC11538390

Examination of allele frequencies and LD patterns suggested multiple independent signals in the region covering the IRF6 gene (Fig. 2b).

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PMC9429973

Quantitative reel time PCR (quantification of AID, cMYC and IgH locus transcripts).

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PMC9878562

Collective migration has been extensively studied to describe the metastasis of solid tumors but is seldom used to describe the movement of hematological cancers in a contact independent manner.

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PMC11261875

Moreover, imatinib-resistant GIST 882 cells were more vulnerable to glycolysis inhibition than GIST 882 cells, whereas imatinib-resistant GIST-T1 cells were more resistant to OXPHOS inhibition than GIST-T1 cells .

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PMC11045125

D. EBV+ Akata BL cells were infected with a lentivirus vector expressing LMP1 or a control lentivirus and two days later cells were treated with puromycin for 3 days.

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PMC11534035

In this work we aimed to uncover the role PAI1 plays in the proliferation, migration, and invasion of vulvar cancer (VC), and define the protein’s function as an oncogene or tumor suppressor.

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PMC10671321

Appropriated Alexa fluorescent secondary antibodies (Invitrogen, Waltham, MA, USA, 1:1000) and Hoechst (5 μg/mL) were added for 1 h. Image acquisitions were performed on the spinning disk confocal (Zeiss®, Jena, Germany) with the 63X objective and CellInsight High content CX7 system (ThermoFisher, Waltham, MA, USA) wit...

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PMC10329074

As shown in Fig. 5C-D, consistently, siYBX3-3 group cells showed significantly decreased proliferation and clone formation, ***P < 0.001.

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PMC10734950

Following resuspension in 500 μl PBS, the cells were given a 30 min recovery period and then analyzed by the flow cytometer.

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PMC7841189

Furthermore, CCK-8 analysis showed that cell proliferation was significantly suppressed in sh-LTBP2-transfected FTC133 cells compared with the mock-transfected control group (Fig. 2C).

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PMC11774251

TNF-α-stimulated HaCaT cells led to a significant reduction in K1 expression and increased levels of K6 and K17 compared to the NC group.

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PMC9429973

By engaging innate-like T cell subsets with inherent antitumor activity, namely Vγ9Vδ2-T and type 1 NKT cells, LAVA-051 has the potential to combine high therapeutic efficacy with limited off-tumor toxicity.

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PMC11291490

As dusCD40L has a high sequence identity among birds (Supplementary Fig. 1), its ability to promote the proliferation of duck PBMCs (duPBMCs) and chicken PBMCs (chPBMCs) was detected in the present study.

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PMC11611077

Since Qmax indicates the total amount of charge carried by all prestin in the cell membrane and e is the electron charge, which is presumed to equal the charge carried by one prestin molecule, the number of prestin molecules in the cell is given by Qmax/e.

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PMC9429973

Plasma cell content ranged according to myelogram from 1 to 89% (Me 26%), paraprotein secretion was 0.1 to 85 g/L, Bens-Jones protein in urine (from trace values to 12.54 g/day) was determined in 54 patients.

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PMC11525028

N-labeled Asn amount in ASNS-KO and control cell lines (n = 3).

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PMC11291490

Conversely, prominent Th2 cytokines, IL-6 and IL-10, play a pivotal role in supporting B cell responses.

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PMC11473843

Scheme of the in vivo experiment workflow.

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PMC11317131

Active phage capable of recombining the AP and CP express gIII and generate progeny containing a functional integrase variant.

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PMC5673060

Phosphopeptides were eluted using 2 × 50 μl of 5% NH4OH solution and 1 × 50 μl pyrrolidine.

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PMC11748335

Consequently, we selected −0.7 as the WScutoff for our analysis.

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PMC11317131

The directed evolution method described here could easily be adapted to further improve these integrases analogous to PhiC31 and Bxb1 integrases.

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PMC9429973

Minimal residual disease (MRD) negativity at 10 was assessed by next-generation sequencing.

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PMC7022782

The particle size of ICG-loaded NPs ranged from 120 to 200 nm and was influenced by the concentration of dye (Table 1).

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PMC11621493

Representative TLC of acylglycerol levels of control (empty vector transfection) and PLA2G4D-expressing COS7 cells loaded with 300 μM rac-18:1 MAG for 210 min in the absence and presence of DGAT1 and DGAT2 inhibitors (5 μM each). (

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PMC9325715

bLTF suspension was mixed with 600 mg/L Fe solutions at the ratio 1:1 (v/v) and incubated with stirring for 24 h (T ≈ 23 °C).

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PMC10530622

The microbiota comprises an enormous collection of microorganisms (viruses, bacteria, archea and eukaryotes) and the majority reside in the GIT.

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PMC11740573

After 24 h, 48 h, and 72 h of further incubation at 37 °C under 5% CO2, cell supernatants were collected and analyzed for levels of cytokines.

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PMC8584666

In recent years, expression of GPI-80 has been found that its expression level may be negatively correlated in survival of cancer patients (The human protein atlas: https://www.proteinatlas.org/ENSG00000112303-VNN2/pathology/renal+cancer; last accessed the link, 6 November 2021).

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PMC9712534

Representative images of FRAP analysis of EGFP-TOP2B WT in the presence of ICRF-187.

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PMC11641532

The CCK-8 assay showed enhanced cell proliferation in HSD3B7-overexpressing cells compared to controls at multiple time points (0, 24, 48, 72, and 96 h) (Figure 7C).

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PMC4839679

Each sample was tested in triplicate.

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PMC11694066

SFs were then used to plot dose–response survival curves, which were generated using three-parameter logistic regression analysis via the drc package in R. Using drc, the AUC values were calculated from the dose–response survival curves.

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PMC10999934

The t-SNE plot demonstrated cell types of chemoresistance samples (left) and chemosensitivity samples (right). (

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PMC9429973

One (2.8%) pt experienced a Gr 5 AE (pneumonia), unrelated to belamaf.

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PMC11539788

In non-small cell lung cancer (NSCLC), Cheng et al. reported that RNF19A was highly expressed in tumour samples and predicted increased carcinogenesis and poor outcomes in patients with NSCLC.

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PMC7685376

Figure 3MCM proteins were up-regulated in HCC cell lines and tissues. (

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PMC11609529

The colony areas were quantified using ImageJ and presented as a percentage of the colony area relative to the corresponding DMSO-treated control groups.

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PMC11218145

However, the toxicity associated with the in vivo i.p.

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PMC7192625

Upon selection of a feature, a table will also appear below the feature selection drop-down menu with a list of network statistics specific to the selected feature.

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PMC10142392

Studies on PCL-based models have shown that drug loading is strongly influenced by the polymer composition and the shape of the nanoparticles . “

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PMC11799978

The total protein (20 μg) was used for blotting.

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PMC9429973

Median age across groups ranged from 65 to 70 y. Baseline clinical characteristics were generally similar across subgroups, but pts with shorter vs longer disease duration were slightly younger with higher blood counts.

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PMC4270159

iii.

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PMC11185260

RT-qPCR analysis of transcriptional expression of SMARCB1 at indicated time after transfection with either scL-SMARCB1 or scL-vec (N = 4 for BT-12, N = 3 for CHLA-06 and A-204). **

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PMC9429973

Median age was 72 years and median Charlson comorbidity index was 4 points.

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PMC11612794

The AlphaFold2 predicted structure of human Mis12C in complex with the aa 176–232 region of human CENP-T is similar to the predicted structure of chicken Mis12C in complex with chicken CENP-T (Figures S3F–S3I).

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PMC11593084

On-target, off-tumor toxicity is a cause of adverse effects when the target antigen is expressed in normal cells.

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PMC9429973

This cohort study included patients with and without prevalent hematologic diseases.

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PMC10723784

In 2017, the FDA approved Olaparib in high‐grade serous ovarian cancer cells independent of BRACA mutations for recurrent ovarian cancer. ,

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PMC11727145

Overall, the novelty and significance of the presented work was the use of optimized methods for DED model setup and the use of patient burn wound exudates in order to obtain an in vitro model with high translational relevance.

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PMC11746942

The peptide of each sample was desalted on C18 cartridges (Empore™ SPE Cartridges, Sigma), concentrated by vacuum centrifugation, and reconstituted in 10 µl of 0.1% (v/v) formic acid.

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PMC10253973

Cytotoxicity and anti-tumor properties can be induced in breast tumor cells by ruthenium complexes.

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PMC11680562

The primary cause of cervical cancer is chronic Human Papilloma Virus (HPV) infection, which affects the squamous cells in the cervix.

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PMC9024365

Data are represented as mean cluster size ± SEM; n.s.

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PMC11539788

Ubiquitin (Ub), a 76-amino acid protein, acts as a linkage site for multiple polyubiquitin chain modifications, which ultimately determine the intracellular function or fate of target proteins .

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PMC11200978

Based on the promising results presented herein, studies with other drugs, combinations, doses, etc.,

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PMC9429973

Results: We identified molecular changes in the plasma of B-ALL patients compared to healthy controls.

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PMC11464982

The production strain is grown as a pure culture using a typical industrial medium in a solid‐state fermentation system with conventional process controls in place.

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PMC8348645

The edible parts of the plants Camellia sinensis, Vitis vinifera and Withania somnifera were extensively used in ancient practices such as Ayurveda, owing to their potent biomedical significance.

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PMC11320834

In a phase II clinical trial from the GINECO group bevacizumab, olaparib, and durvalumab were tested in advanced ovarian cancer patients with platinum-resistant relapse.

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PMC9118379

Or because possible modifications are neglected in the search parameters, spectra of modified peptides can be incorrectly identified as other peptide sequences.

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PMC9429973

Patient perceptions of changes in overall health and disease characteristics since diagnosis/disease onset were evaluated.

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PMC5417661

The IC50 value of NOV202 in the A2780 OC cell line was 2, 4 nM and therefore the plasma concentration in the efficacy study, especially at the 40 mg/kg dose, should be high enough for a potent reduction of tumor volumes in vivo, as shown in Figure 6A.

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PMC11015054

Subsequently, RNA sequencing was performed to analyze the molecular mechanism of METTL5 in HCC based on the sequencing results, and relevant experiments were performed to verify it.

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PMC6133382

While this antibody bound to all of the envelope proteins tested, a small but consistent improvement was observed in binding to the proteins produced in the MGAT1 CHO and HEK 293 GnTI cells compared to the protein produced in the CHO-S cells.

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PMC9429973

There were no differences with age, disease status to HSCT, and prognostic indexs.

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PMC10728200

A GIST-T1 and 882 cells were treated with different concentrations of IM for 24 h and the IC50 of IM was determined.

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PMC11687167

Their results showed that reduced PCSK9 function was associated with accelerated pathogen lipid clearance via LDLR, a decreased inflammatory response, and improved septic shock outcomes .

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PMC4355729

The downregulation of PIK3R1 promotes EMT, migration, and cancer stem cell phenotype in renal cancer cells and may contribute to the progression and metastasis of RCC by activating the PI3K/AKT/GSK3β/CTNNB1 pathway.

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PMC11509224

Axistatins 1–3 showed inhibition against the murine lymphocytic leukemia P388, pancreatic adenocarcinoma BXPC-3, breast adenocarcinoma MCF-7, CNS glioblastoma SF-268, lung large-cell carcinoma NCI-H460, colon adenocarcinoma KM20L2, and prostate carcinoma DU-145 cell lines, with GI50 values of 19.8, 22.8, and 8.9; 4.8, ...

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PMC11697703

For differential miRNA expression analysis, neurons in suspension were FACS-purified into RNAlater (Life Technologies) using a FACS Vantage sorter (BD), and purified labeled neuron cell bodies were then frozen at -80°C until RNA purification.

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PMC9429973

Immunofluorescence showed that BTZ triggered the nuclear translocation of NFATc1.

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PMC11661024

Any distress in microbiota balance can lead to urogenital tract infections, which finally may result in cervical cancer .

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PMC11721295

DAPI was added during the last 5 minutes, and then slides were mounted with Prolong Gold anti-fade reagent (Invitrogen, P36930).

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PMC11679892

The experiments were repeated three times to ensure the reliability of the experiments .

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PMC8041314

In order to confirm the found results with respect to multitarget ABCB1, ABCC1, and ABCG2 inhibition of compounds 15, 18, 21, 22, and 26 as well as ABCG2 inhibition of compound 27, Hoechst 33342 (ABCB1 and ABCG2), and daunorubicin (ABCC1) fluorescence accumulation assays have been performed as described previously with...

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PMC11750165

However, components for Jagged-mediated signaling remain poorly defined during late neurogenesis.

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PMC11787355

D170, P. (2025) https://BioRender.com/z72g103 (b).

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PMC9429973

Due to the high prevalence of acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the pressure of the transfusion department raised proportionally.

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PMC9065483

Representative fluorescence images were captured 24 hpi.

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PMC9429973

RBC-exchange transfusions may also be performed in pts with SCD.

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PMC11682224

Through an imbalance in the p1-cyclinE-CDK53 pathway in gliomas, CHD1L may cause the G2/S transition.

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PMC9429973

Aims: To identify transcriptional and epigenetic characteristics and vulnerabilities of AML MRD, guiding the design of “targeted” combination treatment strategies that successfully eliminate relapse-initiating cells in individual AML patients.

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PMC10040136

The GIST-882 cells that had been treated were then collected.

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PMC8193046

Concentration-effect curves of compound 23 (●) against ABCB1 (A), ABCC1 (B), and ABCG2 (C) as obtained in calcein AM (A and B) and pheophorbide A (C) assays, respectively, compared to the reference inhibitors 2 (A;■), 26 (B; ■), and 27 (C; ■) applying ABCB1-overexpressing A2780/ADR (A), ABCC1-overexpressing H69AR (B), ...

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PMC11763126

A Heatmap of differentially expressed endogenous peptides in ccRCC.

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PMC9019892

By comparison, imatinib inhibited only the autophosphorylated KIT and downstream signalling pathways but not ERK, which was due to reactivated FGFR signalling.

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PMC11298021

It is noteworthy that the combined treatment with miR-3143, miR-3182, and rapamycin resulted in a greater reduction in the expression levels of the target genes compared to the groups that received rapamycin or any of the miRNAs alone (P<0.0001) (Fig. 7F).

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PMC11696576

IC50s calculated by non-linear regression analysis were used as a measure of compound activity for investigating associations with genetic factors.

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PMC7823217

The 3D bioprinted modified constructs were able to form perfusable vasculature within dermal and epidermal skin layers .

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PMC11271800

PD-1/PD-L1 expression alone or in combination induces M2 TAM polarization to weaken tumor-specific immunity and promote tumor progression.

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PMC8193813

All sensors were calibrated before each sampling day under local ambient conditions.

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PMC8922418

Moreover, Ji et al. used dCas9-SunTag-VP64 to target the HIV-1 LTR region and effectively reactivate the provirus in C11 and A10.6 latent cells (Ji et al., 2016).

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PMC11706776

The mechanisms by which potassium channels regulate cell proliferation are the subject of three consensus theories : (1) oscillation of the membrane potential that participates in the control of cell volume and thus allows cells to pass the “cell volume checkpoint” for successful cell cycle progression, (2) potassium e...

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