OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC4395774	The analysis of GFP expression shows that transduction of LSK cells with PGK.PRF leads to GFP expression in all hematopoietic tissues, between 20% in the bone marrow and 50% in the thymus (Supplementary Figure S4a).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11437637	Additionally, some studies have investigated lymphocytes characteristics in patients with EC by comparing them with those of healthy individuals.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "some", ...
PMC11730311	Emax refers to cellular cAMP in the absence of agonist stimulation (100% inhibition).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Emax", "refers", "to", "cellular", "cAMP", "in", ...
PMC9429973	t(4;14) ± del17p was noted in 15 (16.3%) of 92 pts with results available.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "t(4;14", ")", "±", "del17p", "was", ...
PMC11583010	OmniMap anti-rabbit HRP (Roche) was then used to perform DAB staining according to the manufacturer’s instruction (Ventana).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "OmniMap", "a...
PMC11495567	KRAS mutations are the most common oncogenic mutations in lung adenocarcinoma in Black Americans.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "KRAS", "mutations", "are", "the", "most", "common", "oncogenic", ...
PMC11770130	Due to the lack of significant SNPs, we were unable to perform the analysis for food intake.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Due", "to", "the", "lack", "of", ...
PMC11525028	mRNA ac4C modification level measured in 5 matched pairs of osteosarcoma and normal samples by dot blot. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "mRNA", "ac4C", "modification", "level", ...
PMC11790971	Upon receipt of the four CHO cell lines (assigned A, B, C, D for blinded investigation), vials with cells were stored in vapor phase liquid nitrogen.	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11285179	We detected augmented production of angiopoietin-1 in pericytes stimulated by CCL28 (Fig. 3A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "detected", "augmented", "production", "of", "angiopoietin-1...
PMC11367939	Scale bars, A 5 μm (left) or 2 μm (right).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bars", ",", "A", "5", "μm", "(", "left", ...
PMC11593713	An imbalance in the oxygen reactive species (ROS) production and the body’s inability to detoxify them is referred to as oxidative stress .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11144382	RA is required for normal bone development, acting as a morphogen during limb development as homozygous Crabp2 knockout mice were reported to be viable, normal and fertile with the exception for minor limb malformation, with variable penetrance depending on the genetic background.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11322866	EZH2 level was measured by western blot analysis. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "EZH2", "level", "was", "measured", "by", "western", "blot", "analysis", ".", "(" ] } ]
PMC10142392	Furthermore, the increase in the number of PCL arms further reduced the crystallization temperature Tc,PCL of the toothbrush-type copolymer to a remarkably low value (−17.4 °C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11653533	However, some triterpenes like 3β-acetoxy-25-hydroxylanosta-8,23-diene, oleanonic acid, acetylbetulinic acid, betulonic acid, acetylursolic acid, ursonic acid, ursolic acid, and 3-oxofriedelan-28-oic acid were isolated from the aerial roots of Ficus microcarpa have possessed cytotoxicity potential against some human ca...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: We present the first report on real-world outcomes of pts in the PASS receiving commercial brexu-cel for r/r MCL, including pts with no prior exposure to BTK inhibitors (BTKi-naïve) who would otherwise be ineligible for inclusion in the reported ZUMA-2 cohort.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9635307	Thus, CEACAM1 has several splice variants whose names are derived from the number of the extracellular domains and the type of cytoplasmic domain.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11733919	To remove the excess of unbound polymer, the MNPs solution was centrifuged at 24,000 rpm for 2 h four times and redispersed in milli-Q water for further use.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The pre-treatment transcriptomic profile correlated with the IGHV status, trisomy 12, and del13q (B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "pre-treatment", "transcriptomic", "pr...
PMC11745823	The diminished expression of Ki‐67 in xenograft tumours within the c‐Myc silencing cohorts suggests that the silencing of c‐Myc may effectively mitigate the impact of RIT1 on cell proliferation (Figure S5E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7334607	The y axis of all the point-range plots has μM units, except Cyclo, where the unit is percent of chemically activated 4-hydroxycyclophosphamide solution by volume.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11129910	The paraffin-embedded tissue samples were verified and deidentified before the process.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "paraffin-embedded", "tissue", "samples", "were", "verified", "and", "deidentified", ...
PMC11063646	In-vivo cell uptake of ANG 12 by confocal microscopy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In-vivo", "cell", "uptake", "of", "ANG", "12", "by", "confocal", "microscopy", "." ] } ]
PMC11746942	Consistent with the observed phenotypic improvements, S1PR3-KO mice exhibited a significantly attenuated inflammatory response.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Consistent", "with", "the", "observed", "phenotypic", "improvemen...
PMC3813807	However, miR-17–92 is significantly increased in small-cell lung cancers and human B-cell lymphomas and plays a key role in tumorigenesis (24).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11365427	Annexin V-PE/7-AAD apoptosis detection in flow cytometry was applied to MM cell lines after 48 h of phenylalanine deprivation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Annexin", "V-PE/7-AAD", "apoptosis", ...
PMC10079526	28 mice were divided over 4 groups (n = 7 per group), tumor growth was measured twice weekly followed by intra peritoneal injections with the treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	As for the typical organ damage profile, patients with anemia at baseline were more likely to develop musculoskeletal and skin (60.6% vs 39.5%, p<0.001), gastrointestinal (62.3% vs 44.6%, p<0.001), cardiovascular (16.6% vs 10.1%, p=0.046) and renal (3.4% vs 0.0%, p=0.004) system damage compared to patients without anem...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11742290	General architecture of G-protein coupled receptors (GPCRs) consists of an N-terminal domain attached to the 3 intracellular loops (ICL1-ICL3, blue) and three extracellular loops (ECL1-ECL3, green) followed by the C-terminal domain. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11519567	Before fluorescence bleaching, take two consecutive photos to make sure that the selected shooting laser intensity will not bleach the EGFP protein.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Before"...
PMC11569208	Relative viability was measured by resazurin metabolic dye over mock transfected, uninfected controls at indicated timepoints (n = 3, mean ± SD; ****P < 0.0001 by two-way ANOVA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11209164	following the manufacturer’s instructions.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "following", "the", "manufacturer", "’s", "instructions", "." ] } ]
PMC9429973	Hemoglobin level was significantly lower in folate deficiency (p = 0.05).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hemoglobin", "level", "was", "significantly", "lower", "in", "folate", "def...
PMC11762280	We found no significant differences in skin erythema, edema, or erosion between Zbp1 mice and WT mice at 48 h after UVB irradiation (Fig. 6D, E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11612508	This configuration ensures high sensitivity to an external alternating current magnetic field (ACMF).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "configuration", "ensures", "high", "sensitivity", "to", ...
PMC11026382	In all three TYMS backgrounds, the distribution of growth rate effects was bi-modal and reasonably well-described by a double gaussian containing one peak of near-neutral mutations and another (far smaller) peak of mutations with highly deleterious growth rate effects.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10253973	The studies were carried out on the complexes of ruthenium with letrozole (48) (Figure 17), a non-steroidal aromatase inhibitor used in hormone therapy for breast cancer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11705862	A likelihood ratio test (LRT) was used to see if the full model was significantly better than the null model (Alfa = 0.05), and the 95% confidence interval was extracted to get a sense of the variation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11775197	Notably, the PPAR pan-agonist bezafibrate increased the proliferation and survival of tumor-reactive CD8 T cells; it also enhanced the inhibition effect of colon cancer development in mice when combined with PD-1 blockade .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11409031	Hence, it remains crucial to create effective clinical prognostic models and detect fresh biomarkers associated with the onset, progression, and outcome of OV.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11470381	Transfer the plasmid–cell mix into nucleofection cuvettes and nucleofect using program CL-120, specific for the Jurkat cell line, in the Amaxa 4D-Nucleofector system.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", ...
PMC9926039	The untreated control A549 cells and the ones treated with methadone and naloxone were seeded in the upper compartment, adding 500 μl of 10% FBS media to the lower chamber.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11055323	N12 with R3A or K5A mutation loses that capability.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "N12", "with", "R3A", "or", "K5A", "mutation", "loses", "that", "capability", "." ] } ]
PMC9429973	These single cell mutational calls, however, cannot be taken at face value, but need to be analysed through appropriate statistical methods, which are currently missing.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7171147	FAO breaks down fatty acids to produce excess ATP and NADPH to support cell survival.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "FAO", "breaks", "down", "fatty", "acids", "to", "produce", ...
PMC9429973	Residual erythrocytes were lysed with NH4Cl solution, followed by immediate acquisition on BD FACS Lyric or BD LSRII cytometers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Residual", "erythrocytes", "...
PMC10237474	Apart from stable pool expression of a single-chain protein, we also generated a GnTI stable pool to co-express a protein complex from two expression vectors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11528603	Thus, cell cycle arrest, and apoptosis in some extend, might occur in HL60 cells in accordance with the upregulation of CDKN1A.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "token...
PMC11566417	Moreover, the utility of the bovine model as a proxy for human health has been demonstrated in cell types other than those from the mammary gland, e.g., in mesenchymal stromal cells, as described in our previous work, and embryonic tissues, as described by others [15, 94–96].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11319300	We analysed PCHi-C data from primary tissues and cell lines in which we had not only shown an active enhancer chromatin state in MYEOV’s 3′ UTR and 3′ flanking region (Figure 1) but also with documented MYEOV overexpression association with cancer (Jung et al., 2019) (see Supplementary Figure S2).	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7351993	The IA node reconstructs SRS images from the transferred data and produces 4-color SRS images with a typical field of view of 33 × 24 μm and an image size of 122 × 24 pixels.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11714165	After the successful preparation of bone‐targeted NBD nanoparticles, we then assessed the compatibility of the nanoparticles in vivo.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "the", "successful", "pre...
PMC11360263	All in all, our studies suggested a potential role of HCMV infection in the generation and development of a triple-negative breast cancer phenotype.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11794568	D&E) Mitochondrial ATP water was measured in skin melanoma cells overexpressing and knocking down CRIP1 using an ATP assay kit. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "D&E", ")", ...
PMC11021472	We now showed that circZDHHC11 supports BL cell growth by selective knockdown of this transcript, without affecting the linear ZDHHC11 transcripts.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "now", ...
PMC2777936	This "breathing" chromatin both characterized pluripotent cells and was functionally relevant to their ability to differentiate into multiple cell types.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "\"",...
PMC9429973	It evaluates the 7 core anxiety symptoms on a 4-point scale (0-3) with a maximum score of 21.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "evalua...
PMC11574271	To study the role of RON in bladder cell tumorigenesis, a panel of 6 bladder cancer cell lines (5637, T24, BIU87, UMUC-3, TCCSUP, and J82) were analyzed for the RON expression using qRT-PCR and Western blot methods (Fig. 1D, E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine"...
PMC11680578	Subculturing was done when cells reached 70% confluence for further experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Subculturing", "was", "done", "when", "cells", "reached", "70", "%", "confluence...
PMC9429973	IB, ZB and OB were administered to the BALB/c mice at 25, 10 and 10mg/kg respectively by oral gavage once daily for 28 days.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	A. Reiter, J. Gotlib, I. Álvarez-Twose, D. H. Radia, J. Luebke, P. J. Bobbili, A. Wang, C. Norregaard, S. Dimitrijević, E. Sullivan, M. Louie-Gao, J. Schwaab, I. A. Galinsky, C. Perkins, W. R. Sperr, P. Sriskandarajah, A. Chin, S. R. Sendhil, M. S. Duh, P. Valent, D. J. DeAngelo Department of Hematology and Oncology, U...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10577955	Bcl2 (B-cell lymophoma 2)has an efficient role in the apoptosis pathway, it regulates the activity of caspases through cytochrome C sequestering in the mitochondria via inhibiting of protein Bax (Bcl2-Associated X Protein) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10203589	From including Zhang database, SPD (secreted protein database), GPRCDB (A Molecular-Specific Information System for G Protein-Coupled Receptors), AmiGO (Gene Ontology database), Uniprot secreted proteins and Signal Peptide Website (An Information Platform for Signal Sequences and signals Peptide), eight public database...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9545474	P NMR (161 MHz, CDCl3): δ −31.56 ppm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P", "NMR", "(", "161", "MHz", ",", "CDCl3", "):", "δ", "−31.56", "ppm", "...
PMC10818573	Cell lines that contain EBV genes can be broadly classified into two categories.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "lines", "that", "contain", "EBV", "genes", "can", "be", "broa...
PMC11541409	Data mining from the Gene Expression Omnibus (GEO) database revealed that TFRC expression was upregulated in high-risk GIST patients and was indicative of a poor prognosis for recurrence .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11766309	Relationships between YKT6 expression levels and MSI (B) or TMB (C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Relationships", "between", "YKT6", "expression", "levels", "and",...
PMC10578720	Six weeks after rAAV-1.3 HBV injection, mice were treated with dichloroacetate (DCA, 100 mg/kg) or an equivalent volume of saline (0.9% NaCl) once daily by means of i.p.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11453018	In a subset of ES cancer cell lines with non-functional P53, EWS::FLI1 binds to a single GGAA motif in the regulatory elements of P15, independent of P300, and represses its transcription.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11792090	The screened anti-CD70 scFvs were inserted into a CAR structure to create various anti-CD70 CARs (CD70 CARs) ( Figure 1A ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC11765243	All statistical calculations refer to the control group or as indicated by brackets.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "statistical", "calculations", "refer", "to", "the", "control", "grou...
PMC11194678	PD is a neurodegenerative disorder caused by a selective loss of dopaminergic neurons and is associated with both motor and nonmotor defects (Kalia and Lang, 2016).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10899471	Comparisons were statistically significant at P < 0.05 by using unpaired t-test or ANOVA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Comparisons", "were", "statistically", "significant", "at", "P", "<", ...
PMC11541409	Type II TKIs occupy both the ATP-binding site and an allosteric site, which increases their selectivity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Type", "II", "TKIs", "occupy", "both", "the...
PMC11295144	In contrast, the extrasynaptic GABAAR subtypes may still engage in interactions with gephyrin and indirectly with NL2 via their β subunits given that α4, α6, or δ do not bind gephyrin, but this interaction is likely to be weaker and transient and therefore insufficient to stabilize the complex between GABAARs and NL2 t...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10810426	We next determined where reverse transcription intermediates were found in different compartments of dividing and quiescent cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "next", "determined", "where", "reverse", ...
PMC10154881	immune cell activation in TILs was evaluated (Figure 4).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "immune", "cell", "activation", "in", "TILs", "was", "evaluated", "(", "Figure", "4", ...
PMC10213179	We examined the stability of the ATOP aptamer incubated in human serum (50%) over time.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "examined", "the", "stability", "...
PMC10891340	Activation of the mitochondrial intrinsic pathway stimulates mitochondrial oligomerization also known as Bax activation, which leads to the release of Cyt C (Garrido et al., 2006).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10747160	Finally, 55 μL of SARS-CoV-2 pseudoviral solution was added to each low-protein-binding microcentrifuge tube.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Finally", ",", "55", "μL", "of", "SARS-CoV-2", "pseudoviral...
PMC10957991	Besides TRPV4, E-cadherin levels were detected by specific antibodies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Besides", "TRPV4", ",", "E-cadherin", "levels", "were", "detected", "by", "specific", "antibodie...
PMC11727306	To better understand abrin’s potential role in human autoimmune disease it is necessary to gain a better understanding of the cellular and molecular mechanisms of the action of the toxin in different cell types.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3019555	To do so, we generated HeLa cells stably expressing Ago2 shRNA and confirmed KD by qRT-PCR (Fig. 9 A) and immunofluorescence staining (Fig. 9 C, top).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11314247	At 48 h, flow cytometry showed 43.1% of MDA-MB-231 cells in apoptosis (Table 1) and 54.9% for MCF-7 cells treated with HO-AAVPA (Table 2) using its corresponding IC50 for 48 h (Table 3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "...
PMC11661024	Furthermore, although we investigated numerous apoptosis-related genes, a more thorough examination of molecular pathways could provide a more profound understanding of the mechanisms of postbiotic action.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10006224	To date, it is unclear how cohesin engages with DNA to perform its different functions in 3D genome organization and cohesion.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "date",...
PMC8427838	A Immunohistochemistry staining of human kidney tissues with control antibody or with anti-TMIGD1 antibody.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "Immunohistochemistry", "staining", "of", "human", "kidney", "tiss...
PMC11359735	Grey bars indicate detected tryptic peptides (cleavage after Lys and Arg) identified across the indicated datasets, which are listed under the putative GPI-addition sequence for each species.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	These data further support the use of D-Vd as a standard of care in Chinese patients with RRMM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "data", "further", "support", ...
PMC9812014	Dragmacidin-D was able to strongly repress the syncytia formation by HIV in the culture cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Dragmacidin-D", "was", "able", "to", "strongly", "repress", ...
PMC11754094	Analysis was performed with targets +2GtoC with −38 ngRNA in HEK3, 1–10del with +90 ngRNA in HEK3, 5–7del with +48 ngRNA in FANCF.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6160470	All graphics with error bars are presented as mean ± s.d. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "graphics", "with", "error", "bars", "are", "presented", "as", "mean", ...
PMC8068766	Twenty-seven genes were selected based on within or between cell line comparisons that were associated with either selenium or HBV effect.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Twenty-seven", "genes",...
PMC11544122	Colenterazine-H (1 µM) (c) or Colenterazine-400A (10 µM) (b) were added, and BRET was immediately measured in a microplate reader at room temperature.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9672323	The graphs show the mean ± SD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "graphs", "show", "the", "mean", "±", "SD", "." ] } ]
PMC9429973	Nearly all patients identified in the 1 wave of the pandemic were identified from hospital testing, reflecting the lack of availability of widespread testing in the community.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11406030	Our LMTK3BP constructs significantly induced ovarian cancer cell death both in vitro and in vivo.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Our", "LMTK3BP", "constructs", "significantly", "induced", "ovari...
PMC5311252	High GFP expression cell population (more than 1000 times GFP expression than basal cells) were sorted, collected and expanded for further experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11679892	In recent years, intensive studies have been conducted on the role of plant-based bioactive molecules in cancer treatment .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "recent", "years", ",", ...

PMC4395774

The analysis of GFP expression shows that transduction of LSK cells with PGK.PRF leads to GFP expression in all hematopoietic tissues, between 20% in the bone marrow and 50% in the thymus (Supplementary Figure S4a).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11437637

Additionally, some studies have investigated lymphocytes characteristics in patients with EC by comparing them with those of healthy individuals.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "some", ...

PMC11730311

Emax refers to cellular cAMP in the absence of agonist stimulation (100% inhibition).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Emax", "refers", "to", "cellular", "cAMP", "in", ...

PMC9429973

t(4;14) ± del17p was noted in 15 (16.3%) of 92 pts with results available.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "t(4;14", ")", "±", "del17p", "was", ...

PMC11583010

OmniMap anti-rabbit HRP (Roche) was then used to perform DAB staining according to the manufacturer’s instruction (Ventana).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "OmniMap", "a...

PMC11495567

KRAS mutations are the most common oncogenic mutations in lung adenocarcinoma in Black Americans.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "KRAS", "mutations", "are", "the", "most", "common", "oncogenic", ...

PMC11770130

Due to the lack of significant SNPs, we were unable to perform the analysis for food intake.

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PMC11525028

mRNA ac4C modification level measured in 5 matched pairs of osteosarcoma and normal samples by dot blot. (

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PMC11790971

Upon receipt of the four CHO cell lines (assigned A, B, C, D for blinded investigation), vials with cells were stored in vapor phase liquid nitrogen.

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PMC11285179

We detected augmented production of angiopoietin-1 in pericytes stimulated by CCL28 (Fig. 3A).

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PMC11367939

Scale bars, A 5 μm (left) or 2 μm (right).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bars", ",", "A", "5", "μm", "(", "left", ...

PMC11593713

An imbalance in the oxygen reactive species (ROS) production and the body’s inability to detoxify them is referred to as oxidative stress .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC11144382

RA is required for normal bone development, acting as a morphogen during limb development as homozygous Crabp2 knockout mice were reported to be viable, normal and fertile with the exception for minor limb malformation, with variable penetrance depending on the genetic background.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11322866

EZH2 level was measured by western blot analysis. (

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PMC10142392

Furthermore, the increase in the number of PCL arms further reduced the crystallization temperature Tc,PCL of the toothbrush-type copolymer to a remarkably low value (−17.4 °C).

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PMC11653533

However, some triterpenes like 3β-acetoxy-25-hydroxylanosta-8,23-diene, oleanonic acid, acetylbetulinic acid, betulonic acid, acetylursolic acid, ursonic acid, ursolic acid, and 3-oxofriedelan-28-oic acid were isolated from the aerial roots of Ficus microcarpa have possessed cytotoxicity potential against some human ca...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Aims: We present the first report on real-world outcomes of pts in the PASS receiving commercial brexu-cel for r/r MCL, including pts with no prior exposure to BTK inhibitors (BTKi-naïve) who would otherwise be ineligible for inclusion in the reported ZUMA-2 cohort.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9635307

Thus, CEACAM1 has several splice variants whose names are derived from the number of the extracellular domains and the type of cytoplasmic domain.

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PMC11733919

To remove the excess of unbound polymer, the MNPs solution was centrifuged at 24,000 rpm for 2 h four times and redispersed in milli-Q water for further use.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

The pre-treatment transcriptomic profile correlated with the IGHV status, trisomy 12, and del13q (B).

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PMC11745823

The diminished expression of Ki‐67 in xenograft tumours within the c‐Myc silencing cohorts suggests that the silencing of c‐Myc may effectively mitigate the impact of RIT1 on cell proliferation (Figure S5E).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7334607

The y axis of all the point-range plots has μM units, except Cyclo, where the unit is percent of chemically activated 4-hydroxycyclophosphamide solution by volume.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11129910

The paraffin-embedded tissue samples were verified and deidentified before the process.

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PMC11063646

In-vivo cell uptake of ANG 12 by confocal microscopy.

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PMC11746942

Consistent with the observed phenotypic improvements, S1PR3-KO mice exhibited a significantly attenuated inflammatory response.

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PMC3813807

However, miR-17–92 is significantly increased in small-cell lung cancers and human B-cell lymphomas and plays a key role in tumorigenesis (24).

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PMC11365427

Annexin V-PE/7-AAD apoptosis detection in flow cytometry was applied to MM cell lines after 48 h of phenylalanine deprivation.

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PMC10079526

28 mice were divided over 4 groups (n = 7 per group), tumor growth was measured twice weekly followed by intra peritoneal injections with the treatment.

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PMC9429973

As for the typical organ damage profile, patients with anemia at baseline were more likely to develop musculoskeletal and skin (60.6% vs 39.5%, p<0.001), gastrointestinal (62.3% vs 44.6%, p<0.001), cardiovascular (16.6% vs 10.1%, p=0.046) and renal (3.4% vs 0.0%, p=0.004) system damage compared to patients without anem...

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PMC11742290

General architecture of G-protein coupled receptors (GPCRs) consists of an N-terminal domain attached to the 3 intracellular loops (ICL1-ICL3, blue) and three extracellular loops (ECL1-ECL3, green) followed by the C-terminal domain. (

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PMC11519567

Before fluorescence bleaching, take two consecutive photos to make sure that the selected shooting laser intensity will not bleach the EGFP protein.

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PMC11569208

Relative viability was measured by resazurin metabolic dye over mock transfected, uninfected controls at indicated timepoints (n = 3, mean ± SD; ****P < 0.0001 by two-way ANOVA).

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PMC11209164

following the manufacturer’s instructions.

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PMC9429973

Hemoglobin level was significantly lower in folate deficiency (p = 0.05).

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PMC11762280

We found no significant differences in skin erythema, edema, or erosion between Zbp1 mice and WT mice at 48 h after UVB irradiation (Fig. 6D, E).

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PMC11612508

This configuration ensures high sensitivity to an external alternating current magnetic field (ACMF).

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PMC11026382

In all three TYMS backgrounds, the distribution of growth rate effects was bi-modal and reasonably well-described by a double gaussian containing one peak of near-neutral mutations and another (far smaller) peak of mutations with highly deleterious growth rate effects.

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PMC10253973

The studies were carried out on the complexes of ruthenium with letrozole (48) (Figure 17), a non-steroidal aromatase inhibitor used in hormone therapy for breast cancer.

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PMC11705862

A likelihood ratio test (LRT) was used to see if the full model was significantly better than the null model (Alfa = 0.05), and the 95% confidence interval was extracted to get a sense of the variation.

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PMC11775197

Notably, the PPAR pan-agonist bezafibrate increased the proliferation and survival of tumor-reactive CD8 T cells; it also enhanced the inhibition effect of colon cancer development in mice when combined with PD-1 blockade .

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PMC11409031

Hence, it remains crucial to create effective clinical prognostic models and detect fresh biomarkers associated with the onset, progression, and outcome of OV.

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PMC11470381

Transfer the plasmid–cell mix into nucleofection cuvettes and nucleofect using program CL-120, specific for the Jurkat cell line, in the Amaxa 4D-Nucleofector system.

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PMC9926039

The untreated control A549 cells and the ones treated with methadone and naloxone were seeded in the upper compartment, adding 500 μl of 10% FBS media to the lower chamber.

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PMC11055323

N12 with R3A or K5A mutation loses that capability.

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PMC9429973

These single cell mutational calls, however, cannot be taken at face value, but need to be analysed through appropriate statistical methods, which are currently missing.

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PMC7171147

FAO breaks down fatty acids to produce excess ATP and NADPH to support cell survival.

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PMC9429973

Residual erythrocytes were lysed with NH4Cl solution, followed by immediate acquisition on BD FACS Lyric or BD LSRII cytometers.

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PMC10237474

Apart from stable pool expression of a single-chain protein, we also generated a GnTI stable pool to co-express a protein complex from two expression vectors.

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PMC11528603

Thus, cell cycle arrest, and apoptosis in some extend, might occur in HL60 cells in accordance with the upregulation of CDKN1A.

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PMC11566417

Moreover, the utility of the bovine model as a proxy for human health has been demonstrated in cell types other than those from the mammary gland, e.g., in mesenchymal stromal cells, as described in our previous work, and embryonic tissues, as described by others [15, 94–96].

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PMC11319300

We analysed PCHi-C data from primary tissues and cell lines in which we had not only shown an active enhancer chromatin state in MYEOV’s 3′ UTR and 3′ flanking region (Figure 1) but also with documented MYEOV overexpression association with cancer (Jung et al., 2019) (see Supplementary Figure S2).

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PMC7351993

The IA node reconstructs SRS images from the transferred data and produces 4-color SRS images with a typical field of view of 33 × 24 μm and an image size of 122 × 24 pixels.

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PMC11714165

After the successful preparation of bone‐targeted NBD nanoparticles, we then assessed the compatibility of the nanoparticles in vivo.

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PMC11360263

All in all, our studies suggested a potential role of HCMV infection in the generation and development of a triple-negative breast cancer phenotype.

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PMC11794568

D&E) Mitochondrial ATP water was measured in skin melanoma cells overexpressing and knocking down CRIP1 using an ATP assay kit. (

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PMC11021472

We now showed that circZDHHC11 supports BL cell growth by selective knockdown of this transcript, without affecting the linear ZDHHC11 transcripts.

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PMC2777936

This "breathing" chromatin both characterized pluripotent cells and was functionally relevant to their ability to differentiate into multiple cell types.

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PMC9429973

It evaluates the 7 core anxiety symptoms on a 4-point scale (0-3) with a maximum score of 21.

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PMC11574271

To study the role of RON in bladder cell tumorigenesis, a panel of 6 bladder cancer cell lines (5637, T24, BIU87, UMUC-3, TCCSUP, and J82) were analyzed for the RON expression using qRT-PCR and Western blot methods (Fig. 1D, E).

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PMC11680578

Subculturing was done when cells reached 70% confluence for further experiments.

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PMC9429973

IB, ZB and OB were administered to the BALB/c mice at 25, 10 and 10mg/kg respectively by oral gavage once daily for 28 days.

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PMC9429973

A. Reiter, J. Gotlib, I. Álvarez-Twose, D. H. Radia, J. Luebke, P. J. Bobbili, A. Wang, C. Norregaard, S. Dimitrijević, E. Sullivan, M. Louie-Gao, J. Schwaab, I. A. Galinsky, C. Perkins, W. R. Sperr, P. Sriskandarajah, A. Chin, S. R. Sendhil, M. S. Duh, P. Valent, D. J. DeAngelo Department of Hematology and Oncology, U...

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PMC10577955

Bcl2 (B-cell lymophoma 2)has an efficient role in the apoptosis pathway, it regulates the activity of caspases through cytochrome C sequestering in the mitochondria via inhibiting of protein Bax (Bcl2-Associated X Protein) .

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PMC10203589

From including Zhang database, SPD (secreted protein database), GPRCDB (A Molecular-Specific Information System for G Protein-Coupled Receptors), AmiGO (Gene Ontology database), Uniprot secreted proteins and Signal Peptide Website (An Information Platform for Signal Sequences and signals Peptide), eight public database...

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PMC9545474

P NMR (161 MHz, CDCl3): δ −31.56 ppm.

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PMC10818573

Cell lines that contain EBV genes can be broadly classified into two categories.

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PMC11541409

Data mining from the Gene Expression Omnibus (GEO) database revealed that TFRC expression was upregulated in high-risk GIST patients and was indicative of a poor prognosis for recurrence .

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PMC11766309

Relationships between YKT6 expression levels and MSI (B) or TMB (C).

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PMC10578720

Six weeks after rAAV-1.3 HBV injection, mice were treated with dichloroacetate (DCA, 100 mg/kg) or an equivalent volume of saline (0.9% NaCl) once daily by means of i.p.

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PMC11453018

In a subset of ES cancer cell lines with non-functional P53, EWS::FLI1 binds to a single GGAA motif in the regulatory elements of P15, independent of P300, and represses its transcription.

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PMC11792090

The screened anti-CD70 scFvs were inserted into a CAR structure to create various anti-CD70 CARs (CD70 CARs) ( Figure 1A ).

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PMC11765243

All statistical calculations refer to the control group or as indicated by brackets.

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PMC11194678

PD is a neurodegenerative disorder caused by a selective loss of dopaminergic neurons and is associated with both motor and nonmotor defects (Kalia and Lang, 2016).

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PMC10899471

Comparisons were statistically significant at P < 0.05 by using unpaired t-test or ANOVA.

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PMC11541409

Type II TKIs occupy both the ATP-binding site and an allosteric site, which increases their selectivity.

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PMC11295144

In contrast, the extrasynaptic GABAAR subtypes may still engage in interactions with gephyrin and indirectly with NL2 via their β subunits given that α4, α6, or δ do not bind gephyrin, but this interaction is likely to be weaker and transient and therefore insufficient to stabilize the complex between GABAARs and NL2 t...

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PMC10810426

We next determined where reverse transcription intermediates were found in different compartments of dividing and quiescent cells.

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PMC10154881

immune cell activation in TILs was evaluated (Figure 4).

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PMC10213179

We examined the stability of the ATOP aptamer incubated in human serum (50%) over time.

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PMC10891340

Activation of the mitochondrial intrinsic pathway stimulates mitochondrial oligomerization also known as Bax activation, which leads to the release of Cyt C (Garrido et al., 2006).

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PMC10747160

Finally, 55 μL of SARS-CoV-2 pseudoviral solution was added to each low-protein-binding microcentrifuge tube.

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PMC10957991

Besides TRPV4, E-cadherin levels were detected by specific antibodies.

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PMC11727306

To better understand abrin’s potential role in human autoimmune disease it is necessary to gain a better understanding of the cellular and molecular mechanisms of the action of the toxin in different cell types.

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PMC3019555

To do so, we generated HeLa cells stably expressing Ago2 shRNA and confirmed KD by qRT-PCR (Fig. 9 A) and immunofluorescence staining (Fig. 9 C, top).

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PMC11314247

At 48 h, flow cytometry showed 43.1% of MDA-MB-231 cells in apoptosis (Table 1) and 54.9% for MCF-7 cells treated with HO-AAVPA (Table 2) using its corresponding IC50 for 48 h (Table 3).

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PMC11661024

Furthermore, although we investigated numerous apoptosis-related genes, a more thorough examination of molecular pathways could provide a more profound understanding of the mechanisms of postbiotic action.

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PMC10006224

To date, it is unclear how cohesin engages with DNA to perform its different functions in 3D genome organization and cohesion.

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PMC8427838

A Immunohistochemistry staining of human kidney tissues with control antibody or with anti-TMIGD1 antibody.

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PMC11359735

Grey bars indicate detected tryptic peptides (cleavage after Lys and Arg) identified across the indicated datasets, which are listed under the putative GPI-addition sequence for each species.

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PMC9429973

These data further support the use of D-Vd as a standard of care in Chinese patients with RRMM.

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PMC9812014

Dragmacidin-D was able to strongly repress the syncytia formation by HIV in the culture cells.

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PMC11754094

Analysis was performed with targets +2GtoC with −38 ngRNA in HEK3, 1–10del with +90 ngRNA in HEK3, 5–7del with +48 ngRNA in FANCF.

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PMC6160470

All graphics with error bars are presented as mean ± s.d. (

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PMC8068766

Twenty-seven genes were selected based on within or between cell line comparisons that were associated with either selenium or HBV effect.

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PMC11544122

Colenterazine-H (1 µM) (c) or Colenterazine-400A (10 µM) (b) were added, and BRET was immediately measured in a microplate reader at room temperature.

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PMC9672323

The graphs show the mean ± SD.

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PMC9429973

Nearly all patients identified in the 1 wave of the pandemic were identified from hospital testing, reflecting the lack of availability of widespread testing in the community.

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PMC11406030

Our LMTK3BP constructs significantly induced ovarian cancer cell death both in vitro and in vivo.

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PMC5311252

High GFP expression cell population (more than 1000 times GFP expression than basal cells) were sorted, collected and expanded for further experiments.

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PMC11679892

In recent years, intensive studies have been conducted on the role of plant-based bioactive molecules in cancer treatment .

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