OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11461833	qRT-PCR revealed that the level of STXBP5 was increased in HEK293 cells overexpressing HA-progerin + FLAG-STXBP5, Over-vector-FLAG was transfected into HA-progerin-expressing HEK293 cells as the control OE condition. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "...
PMC11680982	After 5 and 10 h of actinomycin D intervention, hsa-miR-23a-5p mimic dramatically lowered HER2 mRNA stability (Fig. 6I) and downregulated HER2 and EGFR protein expression (Fig. 6J).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11643491	In the more aggressive cancer cell subset (A375+), uptake of elongated PS particles increased by 10% compared to spherical particles.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC9429973	Secondary outcomes included overall response rate (ORR), complete response (CR) rate, event free survival (EFS), progression free survival (PFS) and safety.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10743717	It is well known that alcohols with an alkyl >6 carbon have poor solubilities in water.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "well", "known", "that", "alcoho...
PMC11049548	These studies have pointed to alterations of different metabolomic patterns in response to various toxic drugs and/or in comparison between platinum-sensitive and platinum-resistant counterparts .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11283030	Simultaneously, we examined the protein expression of ACLY and p-ACLY (S455) in 786-O, A498, ACHN and 293T cells, and found that ACLY and p-ACLY (S455) were up-regulated in the RCC cells compared with normal 293T cell (Fig. S1e), which suggests that ACLY might be associated with RCC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "I-CellLine", ...
PMC11082662	SMPDL3B promoted ovarian cancer cell migration and invasion. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SMPDL3B", "promoted", "ovarian", "cancer", "cell", "migration", "and", "invasion", ".", "(" ] } ]
PMC11045125	The Src kinase inhibitor dasatinib was purchased from Selleckchem (#S1021), dissolved in DMSO, and used at 1 uM. Immunoblots were performed as previously described .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10380508	Significant molecular differences may exist between male and female RCC patients, and therefore gender-specific RCC studies and personalized gender-specific therapies may be warranted.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11013014	Following general procedure, the crude residue was purified by silica gel column chromatography, using DCM/EtOAc, 4:1 (v/v) as eluent, to obtain the expected product 5 as a white solid with a yield of 82%.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10604092	Moreover, we deduced that these symptoms are induced via inflammation and PTHrP. We further investigated the detailed mechanism underlying SLC transplantation-induced cancer cachexia and characterized the SLC-transplanted rat model.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11610461	Immunohistochemical analyses suggested that PSENEN expression levels in KIRC tumor tissues were markedly higher compared to that in the paracancer tissues (Fig. 2B), and its expression levels increased continuously with the deterioration of cancer (Fig. 2C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2118063	The 5′(flanking regions of Bcl6 (−1772/+245) and Aicda (−840/+79) were PCR amplified from genomic DNA extracted from NFS-202 cells and cloned into the pGL3–Basic Firefly luciferase reporter vector (Promega). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", ...
PMC3035438	We next inserted a Blasticidin S resistance (bsr) marker cassette under control of a β-actin promoter at the EcoRV site downstream of human IgHG1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11225860	This Aurkin A effect warrants further investigation in other cancer cell types and with chemotherapeutic agents that induced drug-resistant polyploidy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "Aurkin", "A", ...
PMC11352666	The DepMap portal includes a multitude of cell lines derived from solid tumors, brain tumors, and hematologic malignancies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "DepMap", "portal", ...
PMC11472639	Table 2Characteristics of cycling above anaerobic threshold with main effect from repeated measures ANOVA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Table", "2Characteristics", "of", "cycling", "above", "anaerobic", "th...
PMC8557138	Emerging evidences have surfaced the role of the nervous system in regulating tumor angiogenesis (Jiang et al. 2020).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Emerging", "evidences", "hav...
PMC11216402	To normalize FPKM values, we divided them by the sample's upper-quartile (75th percentile) expression value and multiplied them by the average upper-quartile values across all samples to scale (upper-quartile normalization), and then, they were log2-transformed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11574271	F J82 cells were transduced with miR-659-3p mimics and a RON overexpression plasmid, followed by validation of RON expression using Western blot analysis.	[ { "tags": [ "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC9261184	As shown in Figure 1, emissions are dominated by CO2 emissions, both from the main engines (45% of total GHGs) and the generator engines (18%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11591038	APP processing by α-secretase?—Besides enhancing BACE1 expression along with increased β-secretase activity, chronic hypoxia decreases the protein expression of a disintegrin and metalloproteinase 10 (ADAM10), which is considered an α-secretase mediating the non-amyloidogenic processing of APP, in the neuronal SH-SY5Y ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11742670	Then, the SMILE formats of the collected drugs beside the Vidarabine are developed for each cell line using the PubChem database and DrugBank database.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11300639	CDK4/6 inhibitors have been widely studied internationally, and there are relevant studies on their application in ccRCC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CDK4/6", "inhibitors", "have", "been", ...
PMC8389560	To reduce toxic effects and stabilize Se, recently, technologies for creating nanoparticles based on this microelement have often been used .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "reduce...
PMC11473843	Tissue sections were then counterstained with Methyl Green (Vector Labs, H-3402), followed by dehydration and mounting.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tissue", "sections", "were",...
PMC11721064	The remaining tissue was cut into 2 × 2 cm pieces and digested with Dispase II (10 mg/mL) at 37 °C for 30 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11291490	b The anti-TMUV IgG in different groups was measured by ELISA at 5 w to 10 w post first vaccination.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "b", "The", "anti-TMUV", ...
PMC8567602	C, LICOR quantitative WBs from whole-cell lysates (WCL) collected from HSSYII human synovial sarcoma cells subjected to 7 days of shRNAs (two sequences each; n = 5 for each sequence of each shRNA) directed against control (Renilla, shRen) or the fusion (SS18–SSX, shSSX), with BAF subunits color coded by BAF, presented ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10955424	Moreover, was noted that dasatinib's ability to induce apoptosis was augmented by 2ME2 .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "was", "noted", "that", "dasatinib", "'s", ...
PMC7136814	Although RMS rarely occurs in adults, the outcomes are significantly worse .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Although", "RMS", "rarely", "occurs", "in", "adults", ",", "the", "outcomes", ...
PMC10170482	Processed samples and prepared standards were pipetted into 96-well plates (Eppendorf, Hamburg, Germany).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Processed", "samples", "and", "prepared", "standa...
PMC11739484	MEXPRESS was selected for this study due to its specialized focus on integrating promoter methylation data with gene expression, making it an ideal platform for exploring the methylation status of MMPs in the TCGA SKCM patient cohort.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11761919	They were orally immunized at 7 to 9, 21 to 23, and 35 to 37 days of age.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "They", "were", "orally", ...
PMC11694066	Cells were plated in 96-well plates at 7,000 cells per well for JN1 cells and 10,000 cells per well for R cells and continuously exposed to drugs for a period of 7 days in culture.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11762280	Fig. 6ZBP1 is a key molecule in UVB-induced keratinocyte PANoptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "6ZBP1", "is", "a", "key", "molecule", "in", "UVB-induced", "keratinocyte", "PANoptosis",...
PMC11488203	Moreover, various constitutively expressed protein levels were unanimously altered in the MSC cultures.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "various", "constitutively", "expressed", "protein", "...
PMC10858941	Currently, several HIF inhibitors are already showing promising results in preclinical studies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Currently", ",", "several", "HIF", "inhibitors", "are", "already", "showing...
PMC7090062	Here, we provide further evidence in GIST cells that miR-30a suppresses autophagy during IM treatment and miR-30a sensitizes GIST cells to IM via an autophagy-related mechanism.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11679326	Polysialylation is also characteristic of lung and colorectal cancer cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Polysialylation", "is", "also", "characteristic", "of", "lung", "and", "colorectal", "cancer", "...
PMC8193813	Tests included sensor performance (linearity, drift, response time, noise, detection limits) in response to anticipated field temperatures, pressure, humidity, and interferences.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Both genes code for proteins with histone acetyltransferase activity crucial for cell cycle control.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Both", "genes", "code", "for", "proteins", "with", "histone", "a...
PMC5833712	Introduction of ERβ into the ERα-positive human epithelial ovarian cancer cell line BG-1 led to decreased basal and E2-induced cell proliferation in vitro.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11655498	ΔNp63α can block the activation of Zp which is mediated by KLF4 and Rta protein (Van Sciver et al., 2021b).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ΔNp63α"...
PMC9429973	Methods: From January 1, 2013, to February 1, 2020, 417 newly diagnosed primary MDS patients in the first affiliated hospital of Zhejiang University with bone marrow (BM) biopsy examination were included.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7342409	It was injected intraperitoneally at a dose of 60 mg/kg once a day for 28 days.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "was", "injected", "intraperitoneally", "at", "a"...
PMC11463018	H NMR (400 MHz, Chloroform-d) δ: 8.02 − 7.97 (m, 2H), 7.89 − 7.84 (m, 2H), 7.49 − 7.39 (m, 3H), 7.36 − 7.31 (m, 1H), 7.03 − 6.98 (m, 2H), 6.89 − 6.84 (m, 1H), 5.06 − 4.97 (m, 1H), 4.68 (d, J = 6.1 Hz, 2H), 3.90 (s, 3H), 3.88 (s, 3H).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11798926	However, we observed a highly significant difference for GluA1 and no difference for GluK2, suggesting that the correlation coefficient for SynDIG4 + GluA1 is unlikely due to chance and therefore biologically relevant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	A paired samples t-test was conducted for significance testing on overall average number of correct responses and for confidence rating, and a McNemar’s test was conducted at the Q or learning objective level (5% significance level, P <.05).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11591794	This pathway, well-known for its critical role in cellular stress responses and apoptosis, appears to be a major target of GA, suggesting its potential as a therapeutic agent in cervical cancer treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11462929	Orange and red bars indicate three and four copy regions, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Orange", "and", "red", "bars", "indicate", "three", "and", "four", "copy", ...
PMC11247842	The rectangles show the input data or output result, the diamonds show the analyses performed The genotypes from SNP arrays were imputed to WGS level using a two-step imputation approach : first, imputation from a medium density (50 k) SNP array genotypes to the high-density (HD) BovineHD array (approx.777 k) and, seco...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3035438	The clones with the highest ratio (#12, #3) were kept for further analysis. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "clones", "with", "the", ...
PMC9479186	It could further inhibit the proliferation, migration, and invasion of HCC cells and induced apoptosis and senescence.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "could", "further", "inhibit...
PMC11757230	Consistent with these reports, our results demonstrate that cADSCs inhibit canine LL cell proliferation in vitro by modulating cell survival and/or the cell cycle.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10604092	In particular, we recorded a remarkable decrease in food intake in the SLC-transplanted rats.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "particular", ",", "we", "recorded", "a", "remarkable"...
PMC11306331	We set out to monitor the effects of OptoMBP-induced dissolution on model transcriptional condensates formed of the oncogenic fusion protein FUS-CHOP, which is associated with liposarcoma.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11534035	CAL39 cells treated with G36 in all tested concentrations showed a higher average proliferation, but not at a statistically significant level.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CAL39", ...
PMC11477621	The reaction mixture was stirred at room temperature for 3 h. The reaction was complete detected by TLC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "reaction", "mixture", "was", "s...
PMC10669966	Instead, we used two PDE3A- and SLFN12-positive LPS cell lines, GOT3 classified as a WDLPS, and SA4 with unspecified histology, which showed responses to PDE3A modulators.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11545737	The lytic transglycosidases LtgA and LtgD remodel cell wall and produce peptidoglycan monomers, which conversely suppress TNF-α and IL-1β by modulating the NOD2 and Toll-Like Receptor-2 (TLR2) signaling pathway in THP-1 macrophages .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10125312	The 786-0 cells were less viable than A549 and HepG2 cells, although the differences were not statistically significant (Figure S6).	[ { "tags": [ "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11473750	p values were also adjusted using the Benjamini–Hochberg method to account for multiple comparisons.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "p", "values", "were", "also", "adjusted", "using", ...
PMC9429973	All patients received HDCT and ASCT in NMSC named after N.I. Pirogov (2018 - 2021).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "patients", "received", "HDCT", "and", ...
PMC11194678	Source data are available for this figure: SourceData F5.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Source", "data", "are", "available", "for", "this", "figure", ":", "SourceData", "F5", "."...
PMC11657744	Equal amounts of protein were loaded onto SDS-PAGE gels, and transferred to polyvinylidene difluoride (PVDF) membrane (Millipore) using a Trans-Blot SD semidry transfer apparatus (Bio-Rad).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11628309	A primary function of this protein is closely linked to- the proper assembly of the SNARE complex, which plays a key role in presynaptic vesicle release (Yoo et al., 2023).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11222184	The protein expression (A) changes in HSPs (HSP27, HSP70, HSP90) and the abundance HSPs in SH-SY5Y (B). (*	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", ...
PMC9429973	Image: Summary/Conclusion: In this study, treatment with mitapivat was associated with early and robust Hb responses with approximately one-third of pts achieving normal Hb levels at least once.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11732523	Overall, there is an improvement in interstitial inflammation and resolution of some of the earlier findings.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Overall", ",", "there", "is", "an", "improv...
PMC11634794	In an experiment investigating the specific cytotoxicity of drug STF-62247 towards VHL-deficient cells, it was observed that VHL-rich cells can overcome the pressure induced by drug STF by enhancing the mobility of LAMP1 towards the nucleus by monitoring the position of lysosomes in cells (39).This observation further ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11740207	Evidence for the presence of LSLCs in cell lines emerged in the 1990s and 2000s, primarily in studies focused on leukemia cell lines such as HL60 (Bonnet and Dick, 1997).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellL...
PMC5363531	On the contrary, when the two drugs were used in combination, the administration produced a cytotoxic behavior, demonstrating strong synergy of the two drugs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11680562	The HRSEM (Thermosceintific Apreo S) was utilized to evaluate the morphology of the gel.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "HRSEM", "(", "Thermosceintific", "Apreo", "S", ...
PMC7917457	NTA was also used to assess the aggregation of VALO-D102 and PeptiCRAd-1 particles.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "NTA", "was", "also", "used", "to", "assess", "the", "aggregation", "o...
PMC8992508	Details and order of the steps depend, to some extent, on the transporter type; more information can be found in the paper by Wilkens.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8557138	Ghosh et al., developed an in vitro melanoma angiogenesis model employing multicellular tumor spheroids arising from differentiated (HBL) or undifferentiated (NA8) melanoma cell lines with the aim to determine the correlation of expression with respect to the differentiation marker of cancer cells along with angiogenes...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "B-CellLine", "...
PMC9429973	LAPTM4B short isoform presented an increased clonogenic potential versus the long isoform.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "LAPTM4B", "short", "isoform", "presented", "an", "increased", "clonogenic", "potential...
PMC11344246	Cell count is measured compared to DMSO treated wells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "count", "is", "measured", "compared", "to", "DMSO", "treated", "wells", "." ] } ]
PMC11759543	About 21 % of high-risk NMIBC patients will progress to MIBC which needs aggressive therapy, including systemic chemotherapy .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "About", "21", "%", "of", "h...
PMC9429973	Gr ≥3 AEs and SAEs were each reported in 9 pts (53%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Gr", "≥3", "AEs", "and", "SAEs", "were", "each", "rep...
PMC11802929	Intrigued by the link between antigenic peptides and T cell phenotypes, we investigated whether a similar connection exists for the physicochemical features of each antigen-associated TCR-CDR3 sequence by overlaying those features on the GEX-UMAP (Fig. 5a, Supplementary Fig. 7a).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11228511	A detailed description is provided in SI Appendix.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "detailed", "description", "is", "provided", "in", "SI", "Appendix", "." ] } ]
PMC11468365	Using omics data with deep learning outperforms DeepDSC, which only depends on a deep learning model.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Using", "omics", "data", "with", "deep", "l...
PMC7185206	To assess whether ADAM10 or ADAM17 activity contributes to tumor surface PD-L1 staining variability, we stained sequential melanoma sections with antibodies against ADAM10, ADAM17, and PD-L1 (Figure 3(b-c), Supplemental Figure 7).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Prognostic group distribution according to the ELN 2017 was found to be favorable in 17 patients (19,5%) with 6 cases of t (8; 21) and 7 cases of inv (16), 4 patients had t(15;17).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11754436	Quantitative PCR (qPCR).	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Quantitative", "PCR", "(", "qPCR", ")", "." ] } ]
PMC11767725	Furthermore, psoriasis shows a reduced presence of commensal bacteria such as Cutibacterium and Corynebacterium.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "psoriasis", "shows", "a", "reduced", "p...
PMC10988808	F Sub-localizations of YAP and CCDC25 were analyzed using immunofluorescence.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "F", "Sub-localizations", "of", "YAP", "and", "CCDC25", "were", "analyzed", "using", "immunofluor...
PMC11802855	Single sample GSEA (ssGSEA) analysis was performed to determine the degree of activation for each pathway, which was recorded as the Enrichment Score (ES).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11618052	C NMR (100 MHz, δ ppm DMSO-d6): 160.88, 159.34, 156.59, 147.34, 143.32, 135.80, 135.07, 130.06, 130.01, 129.61, 129.52, 126.66, 126.28, 126.18, 122.22, 121.83, 119.72, 114.94, 55.63, 26.77.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Pts received up to 5 cycles of blinatumomab as a continuous infusion at standard doses.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Pts", "received", "up", "to", "5", "cycles", "of", "b...
PMC11578343	Despite the fundamental importance of cellular viscoelasticity, a major challenge to its broad adoption at the bench‐side or in the clinic is the accessibility of measurement platforms.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11757131	The addition of different concentrations of 3-HIB to the culture medium did not affect cellular ATP production within the first 0–8 h. However, the addition of 0.8 mM or 1.6 mM 3-HIB to the culture medium significantly increased cellular ATP production compared to the control group at 16 and 24 h (p < 0.05).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11243198	Noncanonical GLI1 activation has been reported in esophageal , glioblastoma , and lung cancers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Noncanonical", "GLI1", "activation", "has", "been", "reported", "in", ...
PMC11283030	Original magnification 200×; bars, 50 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Original", "magnification", "200", "×", ";", "bars", ",", "50", "μm", "." ] } ]
PMC4485786	In the FcIL-7 control group, 4 animals died before day 52 and 3 were sacrificed on day 52 because of excessive tumor growth.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC3915447	Swellable hydrophilic polymer nanoparticles, have recently gained much interests as promising nanoparticulate carriers due to their nanoscale size (50–200 nm) and high stability favorable for intravenous and intracellular drug delivery (4).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11632064	For proliferation curves, cell culture media were changed every day with the renewal of treatments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "proliferation", "curves", ",", "cell", "culture...

PMC11461833

qRT-PCR revealed that the level of STXBP5 was increased in HEK293 cells overexpressing HA-progerin + FLAG-STXBP5, Over-vector-FLAG was transfected into HA-progerin-expressing HEK293 cells as the control OE condition. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "...

PMC11680982

After 5 and 10 h of actinomycin D intervention, hsa-miR-23a-5p mimic dramatically lowered HER2 mRNA stability (Fig. 6I) and downregulated HER2 and EGFR protein expression (Fig. 6J).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11643491

In the more aggressive cancer cell subset (A375+), uptake of elongated PS particles increased by 10% compared to spherical particles.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...

PMC9429973

Secondary outcomes included overall response rate (ORR), complete response (CR) rate, event free survival (EFS), progression free survival (PFS) and safety.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10743717

It is well known that alcohols with an alkyl >6 carbon have poor solubilities in water.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "well", "known", "that", "alcoho...

PMC11049548

These studies have pointed to alterations of different metabolomic patterns in response to various toxic drugs and/or in comparison between platinum-sensitive and platinum-resistant counterparts .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11283030

Simultaneously, we examined the protein expression of ACLY and p-ACLY (S455) in 786-O, A498, ACHN and 293T cells, and found that ACLY and p-ACLY (S455) were up-regulated in the RCC cells compared with normal 293T cell (Fig. S1e), which suggests that ACLY might be associated with RCC.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "I-CellLine", ...

PMC11082662

SMPDL3B promoted ovarian cancer cell migration and invasion. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SMPDL3B", "promoted", "ovarian", "cancer", "cell", "migration", "and", "invasion", ".", "(" ] } ]

PMC11045125

The Src kinase inhibitor dasatinib was purchased from Selleckchem (#S1021), dissolved in DMSO, and used at 1 uM. Immunoblots were performed as previously described .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10380508

Significant molecular differences may exist between male and female RCC patients, and therefore gender-specific RCC studies and personalized gender-specific therapies may be warranted.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11013014

Following general procedure, the crude residue was purified by silica gel column chromatography, using DCM/EtOAc, 4:1 (v/v) as eluent, to obtain the expected product 5 as a white solid with a yield of 82%.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10604092

Moreover, we deduced that these symptoms are induced via inflammation and PTHrP. We further investigated the detailed mechanism underlying SLC transplantation-induced cancer cachexia and characterized the SLC-transplanted rat model.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11610461

Immunohistochemical analyses suggested that PSENEN expression levels in KIRC tumor tissues were markedly higher compared to that in the paracancer tissues (Fig. 2B), and its expression levels increased continuously with the deterioration of cancer (Fig. 2C).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC2118063

The 5′(flanking regions of Bcl6 (−1772/+245) and Aicda (−840/+79) were PCR amplified from genomic DNA extracted from NFS-202 cells and cloned into the pGL3–Basic Firefly luciferase reporter vector (Promega). (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", ...

PMC3035438

We next inserted a Blasticidin S resistance (bsr) marker cassette under control of a β-actin promoter at the EcoRV site downstream of human IgHG1.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC11225860

This Aurkin A effect warrants further investigation in other cancer cell types and with chemotherapeutic agents that induced drug-resistant polyploidy.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "Aurkin", "A", ...

PMC11352666

The DepMap portal includes a multitude of cell lines derived from solid tumors, brain tumors, and hematologic malignancies.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "DepMap", "portal", ...

PMC11472639

Table 2Characteristics of cycling above anaerobic threshold with main effect from repeated measures ANOVA.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Table", "2Characteristics", "of", "cycling", "above", "anaerobic", "th...

PMC8557138

Emerging evidences have surfaced the role of the nervous system in regulating tumor angiogenesis (Jiang et al. 2020).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Emerging", "evidences", "hav...

PMC11216402

To normalize FPKM values, we divided them by the sample's upper-quartile (75th percentile) expression value and multiplied them by the average upper-quartile values across all samples to scale (upper-quartile normalization), and then, they were log2-transformed.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11574271

F J82 cells were transduced with miR-659-3p mimics and a RON overexpression plasmid, followed by validation of RON expression using Western blot analysis.

[ { "tags": [ "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...

PMC9261184

As shown in Figure 1, emissions are dominated by CO2 emissions, both from the main engines (45% of total GHGs) and the generator engines (18%).

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PMC11591038

APP processing by α-secretase?—Besides enhancing BACE1 expression along with increased β-secretase activity, chronic hypoxia decreases the protein expression of a disintegrin and metalloproteinase 10 (ADAM10), which is considered an α-secretase mediating the non-amyloidogenic processing of APP, in the neuronal SH-SY5Y ...

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PMC11742670

Then, the SMILE formats of the collected drugs beside the Vidarabine are developed for each cell line using the PubChem database and DrugBank database.

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PMC11300639

CDK4/6 inhibitors have been widely studied internationally, and there are relevant studies on their application in ccRCC.

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PMC8389560

To reduce toxic effects and stabilize Se, recently, technologies for creating nanoparticles based on this microelement have often been used .

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PMC11473843

Tissue sections were then counterstained with Methyl Green (Vector Labs, H-3402), followed by dehydration and mounting.

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PMC11721064

The remaining tissue was cut into 2 × 2 cm pieces and digested with Dispase II (10 mg/mL) at 37 °C for 30 min.

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PMC11291490

b The anti-TMUV IgG in different groups was measured by ELISA at 5 w to 10 w post first vaccination.

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PMC8567602

C, LICOR quantitative WBs from whole-cell lysates (WCL) collected from HSSYII human synovial sarcoma cells subjected to 7 days of shRNAs (two sequences each; n = 5 for each sequence of each shRNA) directed against control (Renilla, shRen) or the fusion (SS18–SSX, shSSX), with BAF subunits color coded by BAF, presented ...

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PMC10955424

Moreover, was noted that dasatinib's ability to induce apoptosis was augmented by 2ME2 .

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PMC7136814

Although RMS rarely occurs in adults, the outcomes are significantly worse .

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PMC10170482

Processed samples and prepared standards were pipetted into 96-well plates (Eppendorf, Hamburg, Germany).

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PMC11739484

MEXPRESS was selected for this study due to its specialized focus on integrating promoter methylation data with gene expression, making it an ideal platform for exploring the methylation status of MMPs in the TCGA SKCM patient cohort.

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PMC11761919

They were orally immunized at 7 to 9, 21 to 23, and 35 to 37 days of age.

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PMC11694066

Cells were plated in 96-well plates at 7,000 cells per well for JN1 cells and 10,000 cells per well for R cells and continuously exposed to drugs for a period of 7 days in culture.

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PMC11762280

Fig. 6ZBP1 is a key molecule in UVB-induced keratinocyte PANoptosis.

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PMC11488203

Moreover, various constitutively expressed protein levels were unanimously altered in the MSC cultures.

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PMC10858941

Currently, several HIF inhibitors are already showing promising results in preclinical studies.

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PMC7090062

Here, we provide further evidence in GIST cells that miR-30a suppresses autophagy during IM treatment and miR-30a sensitizes GIST cells to IM via an autophagy-related mechanism.

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PMC11679326

Polysialylation is also characteristic of lung and colorectal cancer cells .

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PMC8193813

Tests included sensor performance (linearity, drift, response time, noise, detection limits) in response to anticipated field temperatures, pressure, humidity, and interferences.

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PMC9429973

Both genes code for proteins with histone acetyltransferase activity crucial for cell cycle control.

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PMC5833712

Introduction of ERβ into the ERα-positive human epithelial ovarian cancer cell line BG-1 led to decreased basal and E2-induced cell proliferation in vitro.

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PMC11655498

ΔNp63α can block the activation of Zp which is mediated by KLF4 and Rta protein (Van Sciver et al., 2021b).

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PMC9429973

Methods: From January 1, 2013, to February 1, 2020, 417 newly diagnosed primary MDS patients in the first affiliated hospital of Zhejiang University with bone marrow (BM) biopsy examination were included.

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PMC7342409

It was injected intraperitoneally at a dose of 60 mg/kg once a day for 28 days.

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PMC11463018

H NMR (400 MHz, Chloroform-d) δ: 8.02 − 7.97 (m, 2H), 7.89 − 7.84 (m, 2H), 7.49 − 7.39 (m, 3H), 7.36 − 7.31 (m, 1H), 7.03 − 6.98 (m, 2H), 6.89 − 6.84 (m, 1H), 5.06 − 4.97 (m, 1H), 4.68 (d, J = 6.1 Hz, 2H), 3.90 (s, 3H), 3.88 (s, 3H).

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PMC11798926

However, we observed a highly significant difference for GluA1 and no difference for GluK2, suggesting that the correlation coefficient for SynDIG4 + GluA1 is unlikely due to chance and therefore biologically relevant.

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PMC9429973

A paired samples t-test was conducted for significance testing on overall average number of correct responses and for confidence rating, and a McNemar’s test was conducted at the Q or learning objective level (5% significance level, P <.05).

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PMC11591794

This pathway, well-known for its critical role in cellular stress responses and apoptosis, appears to be a major target of GA, suggesting its potential as a therapeutic agent in cervical cancer treatment.

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PMC11462929

Orange and red bars indicate three and four copy regions, respectively.

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PMC11247842

The rectangles show the input data or output result, the diamonds show the analyses performed The genotypes from SNP arrays were imputed to WGS level using a two-step imputation approach : first, imputation from a medium density (50 k) SNP array genotypes to the high-density (HD) BovineHD array (approx.777 k) and, seco...

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PMC3035438

The clones with the highest ratio (#12, #3) were kept for further analysis. (

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PMC9479186

It could further inhibit the proliferation, migration, and invasion of HCC cells and induced apoptosis and senescence.

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PMC11757230

Consistent with these reports, our results demonstrate that cADSCs inhibit canine LL cell proliferation in vitro by modulating cell survival and/or the cell cycle.

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PMC10604092

In particular, we recorded a remarkable decrease in food intake in the SLC-transplanted rats.

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PMC11306331

We set out to monitor the effects of OptoMBP-induced dissolution on model transcriptional condensates formed of the oncogenic fusion protein FUS-CHOP, which is associated with liposarcoma.

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PMC11534035

CAL39 cells treated with G36 in all tested concentrations showed a higher average proliferation, but not at a statistically significant level.

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PMC11477621

The reaction mixture was stirred at room temperature for 3 h. The reaction was complete detected by TLC.

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PMC10669966

Instead, we used two PDE3A- and SLFN12-positive LPS cell lines, GOT3 classified as a WDLPS, and SA4 with unspecified histology, which showed responses to PDE3A modulators.

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PMC11545737

The lytic transglycosidases LtgA and LtgD remodel cell wall and produce peptidoglycan monomers, which conversely suppress TNF-α and IL-1β by modulating the NOD2 and Toll-Like Receptor-2 (TLR2) signaling pathway in THP-1 macrophages .

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PMC10125312

The 786-0 cells were less viable than A549 and HepG2 cells, although the differences were not statistically significant (Figure S6).

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PMC11473750

p values were also adjusted using the Benjamini–Hochberg method to account for multiple comparisons.

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PMC9429973

All patients received HDCT and ASCT in NMSC named after N.I. Pirogov (2018 - 2021).

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PMC11194678

Source data are available for this figure: SourceData F5.

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PMC11657744

Equal amounts of protein were loaded onto SDS-PAGE gels, and transferred to polyvinylidene difluoride (PVDF) membrane (Millipore) using a Trans-Blot SD semidry transfer apparatus (Bio-Rad).

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PMC11628309

A primary function of this protein is closely linked to- the proper assembly of the SNARE complex, which plays a key role in presynaptic vesicle release (Yoo et al., 2023).

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PMC11222184

The protein expression (A) changes in HSPs (HSP27, HSP70, HSP90) and the abundance HSPs in SH-SY5Y (B). (*

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PMC9429973

Image: Summary/Conclusion: In this study, treatment with mitapivat was associated with early and robust Hb responses with approximately one-third of pts achieving normal Hb levels at least once.

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PMC11732523

Overall, there is an improvement in interstitial inflammation and resolution of some of the earlier findings.

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PMC11634794

In an experiment investigating the specific cytotoxicity of drug STF-62247 towards VHL-deficient cells, it was observed that VHL-rich cells can overcome the pressure induced by drug STF by enhancing the mobility of LAMP1 towards the nucleus by monitoring the position of lysosomes in cells (39).This observation further ...

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PMC11740207

Evidence for the presence of LSLCs in cell lines emerged in the 1990s and 2000s, primarily in studies focused on leukemia cell lines such as HL60 (Bonnet and Dick, 1997).

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PMC5363531

On the contrary, when the two drugs were used in combination, the administration produced a cytotoxic behavior, demonstrating strong synergy of the two drugs.

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PMC11680562

The HRSEM (Thermosceintific Apreo S) was utilized to evaluate the morphology of the gel.

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PMC7917457

NTA was also used to assess the aggregation of VALO-D102 and PeptiCRAd-1 particles.

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PMC8992508

Details and order of the steps depend, to some extent, on the transporter type; more information can be found in the paper by Wilkens.

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PMC8557138

Ghosh et al., developed an in vitro melanoma angiogenesis model employing multicellular tumor spheroids arising from differentiated (HBL) or undifferentiated (NA8) melanoma cell lines with the aim to determine the correlation of expression with respect to the differentiation marker of cancer cells along with angiogenes...

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PMC9429973

LAPTM4B short isoform presented an increased clonogenic potential versus the long isoform.

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PMC11344246

Cell count is measured compared to DMSO treated wells.

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PMC11759543

About 21 % of high-risk NMIBC patients will progress to MIBC which needs aggressive therapy, including systemic chemotherapy .

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PMC9429973

Gr ≥3 AEs and SAEs were each reported in 9 pts (53%).

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PMC11802929

Intrigued by the link between antigenic peptides and T cell phenotypes, we investigated whether a similar connection exists for the physicochemical features of each antigen-associated TCR-CDR3 sequence by overlaying those features on the GEX-UMAP (Fig. 5a, Supplementary Fig. 7a).

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PMC11228511

A detailed description is provided in SI Appendix.

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PMC11468365

Using omics data with deep learning outperforms DeepDSC, which only depends on a deep learning model.

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PMC7185206

To assess whether ADAM10 or ADAM17 activity contributes to tumor surface PD-L1 staining variability, we stained sequential melanoma sections with antibodies against ADAM10, ADAM17, and PD-L1 (Figure 3(b-c), Supplemental Figure 7).

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PMC9429973

Prognostic group distribution according to the ELN 2017 was found to be favorable in 17 patients (19,5%) with 6 cases of t (8; 21) and 7 cases of inv (16), 4 patients had t(15;17).

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PMC11754436

Quantitative PCR (qPCR).

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PMC11767725

Furthermore, psoriasis shows a reduced presence of commensal bacteria such as Cutibacterium and Corynebacterium.

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PMC10988808

F Sub-localizations of YAP and CCDC25 were analyzed using immunofluorescence.

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PMC11802855

Single sample GSEA (ssGSEA) analysis was performed to determine the degree of activation for each pathway, which was recorded as the Enrichment Score (ES).

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PMC11618052

C NMR (100 MHz, δ ppm DMSO-d6): 160.88, 159.34, 156.59, 147.34, 143.32, 135.80, 135.07, 130.06, 130.01, 129.61, 129.52, 126.66, 126.28, 126.18, 122.22, 121.83, 119.72, 114.94, 55.63, 26.77.

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PMC9429973

Pts received up to 5 cycles of blinatumomab as a continuous infusion at standard doses.

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PMC11578343

Despite the fundamental importance of cellular viscoelasticity, a major challenge to its broad adoption at the bench‐side or in the clinic is the accessibility of measurement platforms.

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PMC11757131

The addition of different concentrations of 3-HIB to the culture medium did not affect cellular ATP production within the first 0–8 h. However, the addition of 0.8 mM or 1.6 mM 3-HIB to the culture medium significantly increased cellular ATP production compared to the control group at 16 and 24 h (p < 0.05).

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PMC11243198

Noncanonical GLI1 activation has been reported in esophageal , glioblastoma , and lung cancers.

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PMC11283030

Original magnification 200×; bars, 50 μm.

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PMC4485786

In the FcIL-7 control group, 4 animals died before day 52 and 3 were sacrificed on day 52 because of excessive tumor growth.

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PMC3915447

Swellable hydrophilic polymer nanoparticles, have recently gained much interests as promising nanoparticulate carriers due to their nanoscale size (50–200 nm) and high stability favorable for intravenous and intracellular drug delivery (4).

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PMC11632064

For proliferation curves, cell culture media were changed every day with the renewal of treatments.

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