OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC10957991	3D reconstituted confocal immunofluorescence (IF) images of ctrl siRNA and TRPV4 siRNA-treated MCF10A cells in Matrigel.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ "3D", "reconstituted", "confocal", "...
PMC11380329	The LC-MS/MS analysis of propolis extracts revealed the presence of a complex mixture, and the chemical components of the extracts identified are summarized in Table 1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11687663	The IR spectra of methanolic extract was recorded on a FT-IR (Model Shimadzu 8700) in the range of 400–4000 cm by KBr pellet method .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11612315	c Representative traces from single-channel recordings of TPRV1 channels in the cell-attached configuration.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "c", "Representative", "traces", "from", "single-channel", "recordings", "of", ...
PMC10366908	However, only about five percent of new cancer therapies are approved, and most fail due to the lack of efficacy .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",...
PMC11641630	As shown in Figure 3A,B, M. brumae infection significantly reduced anchorage-independent growth (colony formation) in all BC cell lines, with reductions of 15.5%, 12.3%, and 17.5% for T24, J82, and MB49 cells, respectively, compared to non-infected cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11607764	To start looking into the molecular mechanisms responsible for tumorigenesis of PTBP1, we used STRING, GEPIA2, and DAVID tools to estimate the pathway enrichment of PTBP1-related partners.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10988808	A Knockdown efficiencies of LAST1 in 786-0 cells was detected by Western blot analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "Knockdown", "efficiencies", "of", ...
PMC11216402	For ENCODE DNase-seq normal stomach, we used ENCSR782SSS (Roadmap Epigenomics Consortium et al. 2015) downloaded from the ENCODE Portal (https://www.encodeproject.org), and for TCGA stomach tumor ATAC-seq, we used TCGA-BR-A4J6 (Supplemental Figs. S25, S26; Corces et al. 2018).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11650848	Each row represents a separate clone, while each circle indicates an individual CpG site.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", "row", "represents", "a", "separate", "clone", ",", ...
PMC10329237	CAT activity was expressed as nmol/min/mg protein (22).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CAT", "activity", "was", "expressed", "as", "nmol/min/mg", "protein", "(", "22", ")", "." ...
PMC11787355	c, g and i were analyzed with two-sided Fisher’s exact test.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "c", ",", "g", "and", "i", "were", "analyzed", "with", "two-sided", ...
PMC10291556	Relative lactate concentration in medium following a 6 h treatment of HeLa cells with the investigated compounds at concentrations corresponding to 5× IC50. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11786767	Some nuclear lipids form droplets that serve as nucleolar scaffolding structures, splicing speckles, and DNA repair foci (8, 9, 10).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9412887	Lastly, another challenge that nanomedicines are facing is how to deliver therapeutic agents to defined cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lastly", ",", "another", "challenge", "that", ...
PMC11306019	According to our observation, the antagonistic potency of polyphenols against BTZ is influenced by two factors: the concentration of BTZ used to cause cytotoxicity and the extent to which polyphenols can reduce BTZ-caused cytotoxicity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11486946	The acquisition of single-molecule images began 1 min after the EGF addition.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "acquisition", "of", "single-molecule", "images", "began", "1", "min", "af...
PMC10362265	Viral decoys also showed high fluctuations for region II and the human decoy for region III (Figs. 2a and S4).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Viral", "dec...
PMC9429973	Regarding additional endpoints, the KB algorithm had the highest probability to correctly predict death without previous achievement of a remission (AUCKB = 0.75, Figure 1C, black), restricted prediction for death in first remission (AUCKB = 0.61, Figure 1C, red) or after relapse (AUCKB = 0.63, Figure 1C, blue), but go...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10728535	According to the literature, resistance to platinum‐based drugs is associated with a number of cellular events including decreased concentration of the platinum compounds by either active efflux/sequestration/secretion or impaired influx, detoxification by GSH conjugates, high DNA damage repair levels (nucleotide excis...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11401350	A single systemic injection of this vector encoding for an anti-CD19 CAR into immune deficient mice engrafted with a human blood system generated in vivo CD8 CAR T cells, which effectively wiped out human B cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	10.6% of newly diagnosed DLBCL-patients were not treated with R-CHOP.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "10.6", "%", "of", "newly", "diagnosed", "DLBCL-patients", "were", "not", "treated", "...
PMC11185260	Cells were photographed using an Olympus IX-71 inverted microscope (Olympus Life Sciences, Waltham, MA, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "photographe...
PMC8996378	RF value can be calculated by the MTT method, which can reveal reversal activities and cytotoxicity of compounds.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RF", "value", "can", "be", ...
PMC11644761	Specifically, the selection of a neuroblastoma cell line was driven by its ability to differentiate into neuron-like cells upon retinoic acid treatment and to re-enter the cell division cycle when stimulated with molecules like forskolin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC10957991	Brightfield images are shown, bar 200 um. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Brightfield", "images", "are", "shown", ",", "bar", "200", "um", ".", "(" ] } ]
PMC10900886	Despite this decrease, at 48 hpi, virus titer in the supernatants of imDCs was significantly higher than in mDCs (Fig. 4B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11345828	The reaction mixture was diluted with EtOAc, and washed with brine, dried over MgSO4, filtered, and then concentrated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "react...
PMC9429973	While IL6 (-174) G allele (p = 0.0302), TGF-β1 (T10 / C10) T allele (p = 0.0224), IL10 (-1082) G allele (p = 0.0232), IL10 (-819) C allele (p = 0.0156), IL10 (-592) C allele (p = 00156) was higher in HL patients compared to the control group, expression of IL6 (-174) C allele (p = 0.0302), TGF-β1 (T10 / C10) C allele (...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7334607	Figure 2 shows a temporal collateral sensitivity map that represents the log2 fold change of EC50 to a drug (columns) for an experimental replicate at a given time point (rows) compared with the average EC50 of the three control evolutionary replicates to the same drug, at that time point.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11453018	An advantage of chemical inhibition over siRNA knockdown is its rapid effect.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "An", "advantage", "of", "chemical", "inhibition", "over", "siRNA", "knockdown", ...
PMC5916734	The FIX gene resides on the X chromosome.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "FIX", "gene", "resides", "on", "the", "X", "chromosome", "." ] } ]
PMC9672323	The graphs show the mean ± SD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "graphs", "show", "the", "mean", "±", "SD", "." ] } ]
PMC11200978	MLKL protein levels were not found to differ significantly between any of the conditions (Figure 5A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MLKL", "protein", "levels", "were", "n...
PMC11684297	Table 1 shows the different FTIR peaks obtained with their explanation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Table", "1", "shows", "the", "different", "FTIR", "peaks", "obtained", "with", "their...
PMC11530949	Finally, flow cytometry (BD FACSCalibur Flow Cytometer, USA) was used to analyze the results.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Finally", ",", "flow", "cytometry", "(...
PMC9398137	Our data suggest that BCL2 protein might serve as a buffer for pro-apoptotic proteins released from MCL1 upon exposure to S63845 and induce resistance to S63845 (Fig. 2B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: We report the results of the first patients included since we started the program in 2019.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "We", "report", "the", ...
PMC10419319	Consequently, targeting the dysregulated glycolytic pathway presents a promising strategy for overcoming cisplatin resistance in cancer .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Consequently", ",", "targeting", "the", "dysregul...
PMC2193049	Indeed, the MAGE-3271–279–specific CTL used in the present study was able to recognize the synthetic decapeptide MAGE-3271–280 (50% maximal lysis at 100 nM), although much less efficiently than the 9-mer MAGE-3271–279 (50% maximal lysis at 0.1 nM).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11001582	These layer-specific changes were not due to layer-specific expression of polyGR as immunohistochemistry revealed polyGR expression across all cortical layers (Extended Data Fig. 4i).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11127909	The data are presented as the means ± SEMss; P < 0.05, *P < 0.01 EFHD1 suppresses the opening of the mPTP and reduces the release of cyt c. A WB analysis of cytochrome c (Cyt c) release into the cytosol of 143B-V, 143B-EFHD1, 143BR-shV and 143BR-shEFHD1 cells induced by cisplatin, N = 3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11588085	EB-Stemness and Mesoderm index in OVCAR3-KRAB in normoxia condition and hypoxia condition. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "EB-Stemness", "and", "Mesoderm", "index", "in", "OVCAR3-KRAB", "in", "normo...
PMC8524093	In case of CHIKV, the EIP can be as short as 2 days and quantification of viral RNA can be as high as 10 PFU in salivary gland and 10 PFU in extracted saliva (Dubrulle et al., 2009).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11748335	Gene expression is regulated by epigenetic modifications.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Gene", "expression", "is", "regulated", "by", "epigenetic", "modifications", "." ] } ]
PMC11265931	According to the German Children’s Cancer Database Mainz, approximately 130 children under the age of 14 develop neuroblastomas each year in Germany; therefore, approximately one in every 100,000 children under the age of 15 develops this disease each year.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11139449	JRed expression assay.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "JRed", "expression", "assay", "." ] } ]
PMC11155445	Data from single crystal XRD analysis of compounds (132a, 132b, and 132e) showed that all compounds crystallized in triclinic system adopting the P1̄ space group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11615218	The estimated lower limit to human TCRαβ repertoire diversity stands at 2.5 × 10 to 1 × 10 [ref 123, 124].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC7759933	For the first time, analysis of the expression of genes involved in the proliferation (TOP2A, PCNA, KI67, CCND1, and CDKN1A), apoptosis (BBC3), genes of hepatic markers (AFP and ALB), and gene a transcription factor encoding aryl hydrocarbon receptor (AHR), phase I (CYP1A1, CYP1A2, and CYP3A4), and phase II (UGT1A1, UG...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11739504	White arrows indicate primary cilia.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "White", "arrows", "indicate", "primary", "cilia", "." ] } ]
PMC9429973	All patients were alive at the last follow-up (median follow-up, 11.5 months [IQR 4-21]).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "patients", ...
PMC7334607	In this work, we evolved two EWS cell lines, A673 and TTC466, with repeated exposure to standard-of-care chemotherapy in order to investigate the evolution of collateral sensitivity and resistance through time.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC11676674	Moreover, different sulfur-containing compounds were observed in C. monspeliensis leaf extracts, although it was not possible to identify them precisely from the ms/ms spectrum of the fragmentation pattern obtained by the FastDDA method.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	In addition, we identified risk factors for 30-day mortality by least absolute shrinkage and selection operator (Lasso) regression in a training cohort of 16 centres.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11481779	We have shown 3 examples with σ = (1, 3, 7).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "have", "shown", "3", "examples", "with", "σ", "...
PMC11634794	Firstly, the expression of LAMP1 in ccRCC and its clinical significance were analyzed using various databases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Firstly", ",", "the", "expression", "of", "...
PMC11748335	F The heatmap shows the significance of peak enrichment in DMV regions or transposon regions, with colors representing the -log(q-value) generated by the LOLA R package.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5386478	As recently suggested, our data indicate that TG2 could act as a signaling/scaffold protein or mediate some kind of activity that requires the closed GTP bound conformation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10998613	A short fluorescently tagged DNA oligonucleotide (41 base pairs), with a TAMARA dye on the 5′ end and a 6-FAM dye on the 3′ end, was used to verify the alignment of the system, including the confocal volume overlap.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The most common primary disease was lymphoma/chronic lymphocytic leukemia (n = 18 [82%]), and 1 (5%) patient each had either ALL, AML, neuroblastoma/solid tumor, or myeloma.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10530622	Finally, oxalate has also been associated with the risk of sudden cardiac death in dialysis patients , cardiovascular risk in ESKD and in a stone-forming population in rural China , and progression of CKD , defined as a predictor of kidney function in PH .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9684669	A total of 5,694 genes with a fold change of > 2 and a p-value < 0.05 were identified as differentially expressed genes (DEGs) ( Figure 4A ), including 2,755 genes that were over-expressed and 2,939 genes that were under-expressed in the A2780-ADR cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11185260	Numbers in the quadrants indicate the percentage of cells in each quadrant. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Numbers", "in", "the", "quadrants", "indicate", "the", "percentage", "of", ...
PMC9429973	C. Aoun, N. Salomao, N. Maslah, S. Awan Toor, G. Letort, P. Gou, J.-J. Kiladjian, S. Giraudier, B. Cassinat INSERM U1131-hopital saint louis, Paris, France; Centre d’investigations cliniques; Laboratoire de biologie cellulaire, INSERM U1131-Hopital Saint Louis, Paris, France Background: Myeloproliferative neoplasms (MP...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11765678	Although considerable success has been achieved in inhibiting the activity of ABC transporters in vitro, currently there are no compounds that have successfully inhibited/blocked ABC transporter-mediated resistance in the clinic.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The main indications were lymphoid malignancies 3038 (64.1%), myeloid malignancies 1675 (35.4%), and non-malignant disorders 258 (5.4%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11291490	In this context, duCD80, duMHCI, and duMHCII were chosen as markers representative of APCs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "this", "context", ",", "duCD80", ",",...
PMC11696659	Lung cancer is the leading cause of cancer death among both men and women worldwide, making up almost 25 % of all cancer deaths .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC7192625	Again the H3K27ac is found to have a value close to 0 in the PO subnetworks, suggesting great variability across individuals, an aspect that could not be evaluated for this dataset.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11802929	Overall, APMAT enabled a direct and comprehensive analysis of putative epitopes, supporting prediction algorithms for the common HLA-A*02.01 allele.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Overall", ",", "A...
PMC11762280	Table 3Linear regression analysis of N-GSDMD, cleaved PARP, p-MLKL and age.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Table", "3Linear", "regression", "analysis", "of", "N-GSDMD", ",", "cleaved...
PMC9429973	Methods: Searches (2010 to September 2021) were conducted in MEDLINE, Embase, Cochrane Database of Systematic Reviews, Health Technology Assessment Database, NHS Economic Evaluation Database, and EconLit for real-world studies reporting on HRQoL, utilities, and patient-reported outcomes in adult and pediatric patients ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11266100	Further, the efficiency of GET with the Luciferase-pcDNA3 plasmid and three buffers (No. 1, 2, 5) was characterized using 1.2 kV/cm × 100 μs × 8, 1 Hz and nsPEF 5 kV/cm × 300 ns × 250, 1 MHz protocols and CHO-K1 cell line.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11599565	Communication networks and differentiation of cells in 2D and 3D cell cultures.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Communication", "networks", "and", "differentiation", "of", "cells", "in", "2D", ...
PMC10852540	Depending on the concentration and redox modulation, it can act as an antioxidant or pro-oxidant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Depending", "on", "the", "concentration", "and", "redo...
PMC9429973	Summary/Conclusion: The study started recruitment in 2021 and plans to enroll ~400 patients from approximately 16 countries and 150 sites globally.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Summary/Conclusion...
PMC11612794	The cells were post-fixed for 10 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cells", "were", "post-fixed", "for", "10", "min", "." ] } ]
PMC11536589	Single cell transcriptomes of untreated KPC cells and KPC cells treated with 50 nM MRTX1133 were obtained from the GEO dataset GSE228502 (Mahadevan et al. 2023).	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC8903741	Fig. 4.A ELISA signals of anti-hMMP9 antibody from various colonies following a second round of selection; B SDS-PAGE analysis of expressed anti-hMMP antibodies from #6–5 and #6–9 clones with (+) or without (−) protein reducing; C SDS-PAGE analysis of #6–5 clone after PA affinity chromatography with (+) or without (−) ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11721587	Fu condensates also sustained the treatment of 1.0 M NaCl, 5% 1, 6-hexanediol, or 1% SDS at 4°C, conditions that normally disrupt liquid-liquid phase separation (LLPS) (60), suggesting that Fu condensates were more rigid and gel-like condensates (61).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11700165	Membranes were scanned using Odyssey Imager (LI-COR Biosciences).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Membranes", "were", "scanned", "using", "Odyssey", "Imager", "(", "LI-COR", "Biosciences", ")", ...
PMC11541241	Furthermore, LD biogenesis induced by rapamycin was also observed in various filamentous fungi (Liu et al., 2019).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", ...
PMC11314247	For example, the percentages of apoptotic cells were 5.81% and 5.89% in MCF-7 cells treated separately using the IC50 of VPA and cisplatin, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	One patient treated with PEG had missing data at Week 26 due to being lost to follow-up and was not evaluated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "patient", ...
PMC11046454	Flow cytometry analysis revealed a significant increase in both CD3CD4 and CD3CD8 T cells in the circulation (on day 42) in Group iii and Group iv, while only minimal levels were detected in the DPBS- and Lib-CAR-T treated groups (Figure 5E,F).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10297204	Histological evaluation of the sciatic nerve exposed to three ethanol concentrations (0%, 30%, and 99.5%) was performed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11055323	ns, not significant.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "ns", ",", "not", "significant", "." ] } ]
PMC9512971	Severe cases (e.g., those requiring oxygenation/ventilation) were excluded.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Severe", "cases", "(", "e.g.", ",", "those", "requiring", "oxygenation/ventilation", ")", ...
PMC9429973	In this cohort, 123 (65.4%) and 65 (34.6%) children were splenectomized > or < 3 years of age, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Furthermore, approximately one-fourth of subjects showed moderate or severe signs of anxiety and may, therefore, even be considered as having possible GAD; this incidence of possible cases of GAD is well above that from the general population (~5%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11742431	A comparison shows that although the degradation efficiency of this platform is lower than that of ARMeD, the concept of degradation within the tumor‐specific environment is superior to it.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5308810	The isolated CXCR4 and CXCR4 subpopulations were further characterized for purity by FACS analysis, as described above.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "isolated", "CXCR4", "and", "CXC...
PMC11218145	Twenty NOD-SCID female mice were pseudo-orthotopically inoculated by intra-peritoneal (i.p.)	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Twenty", "NOD-SCID", "female", "mice", "were", "pseudo-orthotopically", "inoculated", ...
PMC9351137	Examples of mitotic defects found in MRG15, Tip60, and YETI depleted S2 cells and their quantification.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Examples", "of", "mitotic", "defects", ...
PMC9429973	Aims: The aim of this report was to investigate long-term safety, disease progression, second-line therapy and survival after autologous NK cell treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9581083	When the formulas are placed on the surface of the muscle, if there is no sweat, there will be no way out for evil, so the sweat method is an appropriate method for treating epidemics.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11772585	Afterward, the colonies were fixed with 10% formaldehyde for 5 min and then stained with 0.1% crystal violet for 20 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11670407	The ultrathin sections were then stained with 1% uranyl acetate and 0.1% lead citrate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "ultrathin", "sections", "were", "then", "staine...
PMC11806818	Simultaneous Biomarker Detection: Advance sensor technology to facilitate the simultaneous detection of multiple biomarkers, focusing on miniaturization and integration to enhance throughput. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC10957991

3D reconstituted confocal immunofluorescence (IF) images of ctrl siRNA and TRPV4 siRNA-treated MCF10A cells in Matrigel.

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PMC11380329

The LC-MS/MS analysis of propolis extracts revealed the presence of a complex mixture, and the chemical components of the extracts identified are summarized in Table 1.

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PMC11687663

The IR spectra of methanolic extract was recorded on a FT-IR (Model Shimadzu 8700) in the range of 400–4000 cm by KBr pellet method .

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PMC11612315

c Representative traces from single-channel recordings of TPRV1 channels in the cell-attached configuration.

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PMC10366908

However, only about five percent of new cancer therapies are approved, and most fail due to the lack of efficacy .

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PMC11641630

As shown in Figure 3A,B, M. brumae infection significantly reduced anchorage-independent growth (colony formation) in all BC cell lines, with reductions of 15.5%, 12.3%, and 17.5% for T24, J82, and MB49 cells, respectively, compared to non-infected cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11607764

To start looking into the molecular mechanisms responsible for tumorigenesis of PTBP1, we used STRING, GEPIA2, and DAVID tools to estimate the pathway enrichment of PTBP1-related partners.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10988808

A Knockdown efficiencies of LAST1 in 786-0 cells was detected by Western blot analysis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "Knockdown", "efficiencies", "of", ...

PMC11216402

For ENCODE DNase-seq normal stomach, we used ENCSR782SSS (Roadmap Epigenomics Consortium et al. 2015) downloaded from the ENCODE Portal (https://www.encodeproject.org), and for TCGA stomach tumor ATAC-seq, we used TCGA-BR-A4J6 (Supplemental Figs. S25, S26; Corces et al. 2018).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11650848

Each row represents a separate clone, while each circle indicates an individual CpG site.

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PMC10329237

CAT activity was expressed as nmol/min/mg protein (22).

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PMC11787355

c, g and i were analyzed with two-sided Fisher’s exact test.

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PMC10291556

Relative lactate concentration in medium following a 6 h treatment of HeLa cells with the investigated compounds at concentrations corresponding to 5× IC50. (

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PMC11786767

Some nuclear lipids form droplets that serve as nucleolar scaffolding structures, splicing speckles, and DNA repair foci (8, 9, 10).

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PMC9412887

Lastly, another challenge that nanomedicines are facing is how to deliver therapeutic agents to defined cells.

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PMC11306019

According to our observation, the antagonistic potency of polyphenols against BTZ is influenced by two factors: the concentration of BTZ used to cause cytotoxicity and the extent to which polyphenols can reduce BTZ-caused cytotoxicity.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11486946

The acquisition of single-molecule images began 1 min after the EGF addition.

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PMC10362265

Viral decoys also showed high fluctuations for region II and the human decoy for region III (Figs. 2a and S4).

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PMC9429973

Regarding additional endpoints, the KB algorithm had the highest probability to correctly predict death without previous achievement of a remission (AUCKB = 0.75, Figure 1C, black), restricted prediction for death in first remission (AUCKB = 0.61, Figure 1C, red) or after relapse (AUCKB = 0.63, Figure 1C, blue), but go...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10728535

According to the literature, resistance to platinum‐based drugs is associated with a number of cellular events including decreased concentration of the platinum compounds by either active efflux/sequestration/secretion or impaired influx, detoxification by GSH conjugates, high DNA damage repair levels (nucleotide excis...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11401350

A single systemic injection of this vector encoding for an anti-CD19 CAR into immune deficient mice engrafted with a human blood system generated in vivo CD8 CAR T cells, which effectively wiped out human B cells .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

10.6% of newly diagnosed DLBCL-patients were not treated with R-CHOP.

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PMC11185260

Cells were photographed using an Olympus IX-71 inverted microscope (Olympus Life Sciences, Waltham, MA, USA).

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PMC8996378

RF value can be calculated by the MTT method, which can reveal reversal activities and cytotoxicity of compounds.

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PMC11644761

Specifically, the selection of a neuroblastoma cell line was driven by its ability to differentiate into neuron-like cells upon retinoic acid treatment and to re-enter the cell division cycle when stimulated with molecules like forskolin.

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PMC10957991

Brightfield images are shown, bar 200 um. (

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PMC10900886

Despite this decrease, at 48 hpi, virus titer in the supernatants of imDCs was significantly higher than in mDCs (Fig. 4B).

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PMC11345828

The reaction mixture was diluted with EtOAc, and washed with brine, dried over MgSO4, filtered, and then concentrated.

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PMC9429973

While IL6 (-174) G allele (p = 0.0302), TGF-β1 (T10 / C10) T allele (p = 0.0224), IL10 (-1082) G allele (p = 0.0232), IL10 (-819) C allele (p = 0.0156), IL10 (-592) C allele (p = 00156) was higher in HL patients compared to the control group, expression of IL6 (-174) C allele (p = 0.0302), TGF-β1 (T10 / C10) C allele (...

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PMC7334607

Figure 2 shows a temporal collateral sensitivity map that represents the log2 fold change of EC50 to a drug (columns) for an experimental replicate at a given time point (rows) compared with the average EC50 of the three control evolutionary replicates to the same drug, at that time point.

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PMC11453018

An advantage of chemical inhibition over siRNA knockdown is its rapid effect.

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PMC5916734

The FIX gene resides on the X chromosome.

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PMC9672323

The graphs show the mean ± SD.

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PMC11200978

MLKL protein levels were not found to differ significantly between any of the conditions (Figure 5A).

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PMC11684297

Table 1 shows the different FTIR peaks obtained with their explanation.

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PMC11530949

Finally, flow cytometry (BD FACSCalibur Flow Cytometer, USA) was used to analyze the results.

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PMC9398137

Our data suggest that BCL2 protein might serve as a buffer for pro-apoptotic proteins released from MCL1 upon exposure to S63845 and induce resistance to S63845 (Fig. 2B).

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PMC9429973

Aims: We report the results of the first patients included since we started the program in 2019.

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PMC10419319

Consequently, targeting the dysregulated glycolytic pathway presents a promising strategy for overcoming cisplatin resistance in cancer .

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PMC2193049

Indeed, the MAGE-3271–279–specific CTL used in the present study was able to recognize the synthetic decapeptide MAGE-3271–280 (50% maximal lysis at 100 nM), although much less efficiently than the 9-mer MAGE-3271–279 (50% maximal lysis at 0.1 nM).

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PMC11001582

These layer-specific changes were not due to layer-specific expression of polyGR as immunohistochemistry revealed polyGR expression across all cortical layers (Extended Data Fig. 4i).

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PMC11127909

The data are presented as the means ± SEMss; *P < 0.05, **P < 0.01 EFHD1 suppresses the opening of the mPTP and reduces the release of cyt c. A WB analysis of cytochrome c (Cyt c) release into the cytosol of 143B-V, 143B-EFHD1, 143BR-shV and 143BR-shEFHD1 cells induced by cisplatin, N = 3.

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PMC11588085

EB-Stemness and Mesoderm index in OVCAR3-KRAB in normoxia condition and hypoxia condition. (

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PMC8524093

In case of CHIKV, the EIP can be as short as 2 days and quantification of viral RNA can be as high as 10 PFU in salivary gland and 10 PFU in extracted saliva (Dubrulle et al., 2009).

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PMC11748335

Gene expression is regulated by epigenetic modifications.

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PMC11265931

According to the German Children’s Cancer Database Mainz, approximately 130 children under the age of 14 develop neuroblastomas each year in Germany; therefore, approximately one in every 100,000 children under the age of 15 develops this disease each year.

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PMC11139449

JRed expression assay.

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PMC11155445

Data from single crystal XRD analysis of compounds (132a, 132b, and 132e) showed that all compounds crystallized in triclinic system adopting the P1̄ space group.

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PMC11615218

The estimated lower limit to human TCRαβ repertoire diversity stands at 2.5 × 10 to 1 × 10 [ref 123, 124].

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PMC7759933

For the first time, analysis of the expression of genes involved in the proliferation (TOP2A, PCNA, KI67, CCND1, and CDKN1A), apoptosis (BBC3), genes of hepatic markers (AFP and ALB), and gene a transcription factor encoding aryl hydrocarbon receptor (AHR), phase I (CYP1A1, CYP1A2, and CYP3A4), and phase II (UGT1A1, UG...

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PMC11739504

White arrows indicate primary cilia.

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PMC9429973

All patients were alive at the last follow-up (median follow-up, 11.5 months [IQR 4-21]).

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PMC7334607

In this work, we evolved two EWS cell lines, A673 and TTC466, with repeated exposure to standard-of-care chemotherapy in order to investigate the evolution of collateral sensitivity and resistance through time.

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PMC11676674

Moreover, different sulfur-containing compounds were observed in C. monspeliensis leaf extracts, although it was not possible to identify them precisely from the ms/ms spectrum of the fragmentation pattern obtained by the FastDDA method.

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PMC9429973

In addition, we identified risk factors for 30-day mortality by least absolute shrinkage and selection operator (Lasso) regression in a training cohort of 16 centres.

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PMC11481779

We have shown 3 examples with σ = (1, 3, 7).

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PMC11634794

Firstly, the expression of LAMP1 in ccRCC and its clinical significance were analyzed using various databases.

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PMC11748335

F The heatmap shows the significance of peak enrichment in DMV regions or transposon regions, with colors representing the -log(q-value) generated by the LOLA R package.

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PMC5386478

As recently suggested, our data indicate that TG2 could act as a signaling/scaffold protein or mediate some kind of activity that requires the closed GTP bound conformation.

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PMC10998613

A short fluorescently tagged DNA oligonucleotide (41 base pairs), with a TAMARA dye on the 5′ end and a 6-FAM dye on the 3′ end, was used to verify the alignment of the system, including the confocal volume overlap.

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PMC9429973

The most common primary disease was lymphoma/chronic lymphocytic leukemia (n = 18 [82%]), and 1 (5%) patient each had either ALL, AML, neuroblastoma/solid tumor, or myeloma.

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PMC10530622

Finally, oxalate has also been associated with the risk of sudden cardiac death in dialysis patients , cardiovascular risk in ESKD and in a stone-forming population in rural China , and progression of CKD , defined as a predictor of kidney function in PH .

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PMC9684669

A total of 5,694 genes with a fold change of > 2 and a p-value < 0.05 were identified as differentially expressed genes (DEGs) ( Figure 4A ), including 2,755 genes that were over-expressed and 2,939 genes that were under-expressed in the A2780-ADR cells.

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PMC11185260

Numbers in the quadrants indicate the percentage of cells in each quadrant. (

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PMC9429973

C. Aoun, N. Salomao, N. Maslah, S. Awan Toor, G. Letort, P. Gou, J.-J. Kiladjian, S. Giraudier, B. Cassinat INSERM U1131-hopital saint louis, Paris, France; Centre d’investigations cliniques; Laboratoire de biologie cellulaire, INSERM U1131-Hopital Saint Louis, Paris, France Background: Myeloproliferative neoplasms (MP...

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PMC11765678

Although considerable success has been achieved in inhibiting the activity of ABC transporters in vitro, currently there are no compounds that have successfully inhibited/blocked ABC transporter-mediated resistance in the clinic.

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PMC9429973

The main indications were lymphoid malignancies 3038 (64.1%), myeloid malignancies 1675 (35.4%), and non-malignant disorders 258 (5.4%).

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PMC11291490

In this context, duCD80, duMHCI, and duMHCII were chosen as markers representative of APCs.

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PMC11696659

Lung cancer is the leading cause of cancer death among both men and women worldwide, making up almost 25 % of all cancer deaths .

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PMC7192625

Again the H3K27ac is found to have a value close to 0 in the PO subnetworks, suggesting great variability across individuals, an aspect that could not be evaluated for this dataset.

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PMC11802929

Overall, APMAT enabled a direct and comprehensive analysis of putative epitopes, supporting prediction algorithms for the common HLA-A*02.01 allele.

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PMC11762280

Table 3Linear regression analysis of N-GSDMD, cleaved PARP, p-MLKL and age.

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PMC9429973

Methods: Searches (2010 to September 2021) were conducted in MEDLINE, Embase, Cochrane Database of Systematic Reviews, Health Technology Assessment Database, NHS Economic Evaluation Database, and EconLit for real-world studies reporting on HRQoL, utilities, and patient-reported outcomes in adult and pediatric patients ...

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PMC11266100

Further, the efficiency of GET with the Luciferase-pcDNA3 plasmid and three buffers (No. 1, 2, 5) was characterized using 1.2 kV/cm × 100 μs × 8, 1 Hz and nsPEF 5 kV/cm × 300 ns × 250, 1 MHz protocols and CHO-K1 cell line.

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PMC11599565

Communication networks and differentiation of cells in 2D and 3D cell cultures.

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PMC10852540

Depending on the concentration and redox modulation, it can act as an antioxidant or pro-oxidant.

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PMC9429973

Summary/Conclusion: The study started recruitment in 2021 and plans to enroll ~400 patients from approximately 16 countries and 150 sites globally.

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PMC11612794

The cells were post-fixed for 10 min.

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PMC11536589

Single cell transcriptomes of untreated KPC cells and KPC cells treated with 50 nM MRTX1133 were obtained from the GEO dataset GSE228502 (Mahadevan et al. 2023).

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PMC8903741

Fig. 4.A ELISA signals of anti-hMMP9 antibody from various colonies following a second round of selection; B SDS-PAGE analysis of expressed anti-hMMP antibodies from #6–5 and #6–9 clones with (+) or without (−) protein reducing; C SDS-PAGE analysis of #6–5 clone after PA affinity chromatography with (+) or without (−) ...

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PMC11721587

Fu condensates also sustained the treatment of 1.0 M NaCl, 5% 1, 6-hexanediol, or 1% SDS at 4°C, conditions that normally disrupt liquid-liquid phase separation (LLPS) (60), suggesting that Fu condensates were more rigid and gel-like condensates (61).

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PMC11700165

Membranes were scanned using Odyssey Imager (LI-COR Biosciences).

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PMC11541241

Furthermore, LD biogenesis induced by rapamycin was also observed in various filamentous fungi (Liu et al., 2019).

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PMC11314247

For example, the percentages of apoptotic cells were 5.81% and 5.89% in MCF-7 cells treated separately using the IC50 of VPA and cisplatin, respectively.

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PMC9429973

One patient treated with PEG had missing data at Week 26 due to being lost to follow-up and was not evaluated.

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PMC11046454

Flow cytometry analysis revealed a significant increase in both CD3CD4 and CD3CD8 T cells in the circulation (on day 42) in Group iii and Group iv, while only minimal levels were detected in the DPBS- and Lib-CAR-T treated groups (Figure 5E,F).

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PMC10297204

Histological evaluation of the sciatic nerve exposed to three ethanol concentrations (0%, 30%, and 99.5%) was performed.

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PMC11055323

ns, not significant.

[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "ns", ",", "not", "significant", "." ] } ]

PMC9512971

Severe cases (e.g., those requiring oxygenation/ventilation) were excluded.

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PMC9429973

In this cohort, 123 (65.4%) and 65 (34.6%) children were splenectomized > or < 3 years of age, respectively.

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PMC9429973

Furthermore, approximately one-fourth of subjects showed moderate or severe signs of anxiety and may, therefore, even be considered as having possible GAD; this incidence of possible cases of GAD is well above that from the general population (~5%).

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PMC11742431

A comparison shows that although the degradation efficiency of this platform is lower than that of ARMeD, the concept of degradation within the tumor‐specific environment is superior to it.

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PMC5308810

The isolated CXCR4 and CXCR4 subpopulations were further characterized for purity by FACS analysis, as described above.

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PMC11218145

Twenty NOD-SCID female mice were pseudo-orthotopically inoculated by intra-peritoneal (i.p.)

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PMC9351137

Examples of mitotic defects found in MRG15, Tip60, and YETI depleted S2 cells and their quantification.

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PMC9429973

Aims: The aim of this report was to investigate long-term safety, disease progression, second-line therapy and survival after autologous NK cell treatment.

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PMC9581083

When the formulas are placed on the surface of the muscle, if there is no sweat, there will be no way out for evil, so the sweat method is an appropriate method for treating epidemics.

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PMC11772585

Afterward, the colonies were fixed with 10% formaldehyde for 5 min and then stained with 0.1% crystal violet for 20 min.

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PMC11670407

The ultrathin sections were then stained with 1% uranyl acetate and 0.1% lead citrate.

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PMC11806818

Simultaneous Biomarker Detection: Advance sensor technology to facilitate the simultaneous detection of multiple biomarkers, focusing on miniaturization and integration to enhance throughput. (

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