OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11222184	SH-SY5Y cells were exposed to various concentrations of Hsp90 inhibitors for 24 h and 48 h. There was a dose- and time-dependent decrease in SH-SY5Y cell viability against HSP90 inhibitors.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "...
PMC9429973	Patients who were refractory/relapsed <12 months from 1 line (1L) therapy, eligible for a stem cell transplant (SCT) at initial relapse/refractory, had an ECOG performance score of 0-1 and had no history of hepatitis B or C or CNS events were studied.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11755467	Due to the absence of any biological effect of nalidixic acid on HIV-1 replication, we continued to study the impact of Enoxacin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Due", ...
PMC11656657	The circulating human T-cells were evaluated periodically in mice peripheral blood.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "circulating", "human", "T-cells", "were", "evaluated", "periodically", "in", "mice",...
PMC5925824	3LY3300054 enhances T cell activation in vitro.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "3LY3300054", "enhances", "T", "cell", "activation", "in", "vitro", "." ] } ]
PMC9429973	Mechanismly, Asxl1 deletion in Jak2 HSPCs leads to enhancer activation of polycomb group (PcG) target genes, such as Egr1 (Figure 1H).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3675084	The DNA content was analyzed based on propidium iodide fluorescence using FACSCalibur equipped with a 488 nm laser and a 610±20 nm band-pass filter.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11788920	Therefore, the Cy3 signal correlates with the quantity of all transcription events, while the Cy5 signal correlates with the quantity of events that reach the end, meaning culmination in a full-length RNA product.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7917457	The numbers of mice in each group were 8−10.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "numbers", "of", "mice", "in", "each", "group", "were", "8−10", "." ] } ]
PMC11754784	A widely existed bottleneck of microenvironment-confined DNA computing strategies is the slow computing speed and weak output signal.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "widely", "existed", "bottleneck", ...
PMC7553912	In the present study, OSM induced the expressions of crystal-binding molecules, including OPN, ANXA1, and ANXA2, in the cultured renal fibroblasts.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10936243	In the second phase, the qualitative semi-structured interview was used to help explain the quantitative results in more depth, so as to understand the context in which these barriers were encountered; such barriers having been indicated in the first phase of this study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8073654	Trans-3-(3′4′-dimethoxyphenyl)-4-[(E)-3′′,4′′-dimethoxystyryl]cyclohex-1-ene (11), and cis-3-(3′4′-dimethoxyphenyl)-4-[(E)-3′′,4′′-dimethoxystyryl]cyclohex-1-ene (4) have exerted neurotrophic effects by inducing neurite sprouting in PC12 cells and triggering neurogenesis and neurite growth and protection in primary cul...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The most common adverse events (≥10% occurrence) were neutropenia (n=13), thrombocytopenia (n=12), asthenia (n=9), anemia (n=7), rash (n=4), diarrhea (n=3), dizziness (n=3), general physical health deterioration (n=3), muscle spasms (n=3), peripheral oedema (n=3), pyrexia (n=3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11747467	The DEGs were further screened using the filtering standard of \|logFC\| > 1 and the adjusted p-value (adj.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "DEGs", "were", "further", ...
PMC11626627	By conducting an analysis of TWIST1 in the TIMER database , we found a differential expression of TWIST1 in various solid tumors, with high expression in Kidney Clear Cell Carcinoma (KIRC) (Fig. 2A, B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7602170	Various inhibitory drugs targeting different parts of the PI3K/AKT/mTOR pathway are currently being investigated in phase Ι and phase ΙΙ clinical trials.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Various", "i...
PMC11321678	Interestingly, HOX family genes which relate to embryonic development, morphogenesis, and differentiation, are associated with subgroup‐specific CCAN (Figure S5B, Supporting Information).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9046263	We performed a correlation and clustering analysis of HERV expression in our cell lines of interest, as shown in Fig. 1B.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "perfor...
PMC3995603	Chronic use can also be associated with significant adverse effects.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Chronic", "use", "can", "also", "be", "associated", "with", "significant", "adverse", "effects",...
PMC11768927	A promising approach to enhance oncolytic selectivity and reduce neurotoxicity involves the use of recombinant VSV encoding the IFN-β gene (VSV-IFNβ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", ...
PMC9856122	For example, clinicians investigated the effects of BBR (NCT04479202) on intestinal function, serum concentrations of inflammatory biomarkers, and organ function in severe SARS-CoV-2-infected patients in a prospective randomized controlled clinical trial supported by the Chinese medical association.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10024132	The findings validate our previous study , while further showing that the combination of γ9δ2 T cells and blinatumomab can clear xenografted ALL cells from bone marrow.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11438317	This way, we found FYB, HPK-1, Vav, SLP76, LCK, HS1, Pyk2, and Syk in LP-DACS precipitates (Fig. 1C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11643491	The entrapment efficiency of paclitaxel within the particles was 32.5% as determined by HPLC (Figure 5C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "entrapment", "efficiency", ...
PMC9429973	Patients with the underlying diagnosis of hematologic malignancies were included.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "with", "the", "underlying", "diagnosis", "of", "hematologic", "malignancies", "were", ...
PMC11453018	In proliferative ES cells, the EWS::FLI1/P300 complex induces LMNB1 by binding to its enhancer motif containing 14 GGAA repeats.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "proliferative", "ES", ...
PMC9429973	Vamifeport inhibits ferroportin-mediated iron export into plasma and has been shown to decrease serum iron and transferrin saturation (TSAT) levels in relevant animal disease models and healthy volunteers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11591794	With their combination, the dose of chemotherapy agent used could be lower and effective anticancer properties would be revealed with GA, which has antioxidant properties.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11194678	The same sample of STAU1 WT were used in evaluating STAU1 LLPS disruption with salt or 1,6 HD. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "same", "sample", "of", ...
PMC9429973	In the H12O, median OS was 45.1, 45.2, 65.1 months and not reached for the 1999-2009, 2010-2014 and 2015-2019 periods, respectively (p=0.001).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8633974	b-c) Transmission electron microscopy images of the CRISPR-Cas9 loaded LNPs showed monodispersed spherical morphology, including a particle surface corona.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "b-c", ")", "Trans...
PMC4270159	c. Incubate for ∼1 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "c.", "Incubate", "for", "∼1", "min", "." ] } ]
PMC11736898	However, reduction of VDR expression levels, and/or reduction of VDR nuclear localization (which may be related to levels of vitamin D present [64–66]), may render keloid cells resistant to the therapeutic effects of vitamin D or other anti-keloid interventions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10114490	Epidermal growth factor (EGF) and transforming growth factor beta (TGFβ) were purchased to PeproTech.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Epidermal", "growth", "factor", "(", "...
PMC11628904	Full fin regrowth, indicating successful wound healing, occurs at roughly 72 hpb (Figure 1B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Full", "fin", "regrowth", ",", "indica...
PMC3164356	Consistent with this, a homolog to this gene is found in the CHO-K1 genome but is not expressed (Fig. 3b,i).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC11543935	The alcian blue staining (Fig. 5A) further showed no optical cell polarization is present throughout the section indicating a successful nutrient supply throughout the gel.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11564322	In all the studied cell lines, the VVGPGA peptide co-treatment with the c-SRC inhibitor I increased the KI67 mRNA expression, compared to the control (by 24.01% in the HL-60 cell line, by 36.62% in the K562 cell line, and by 26.99% in the MEG-A2 cell line) (Fig. 2A–C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11562028	The obtained CDs had an anti-human colon cancer cell HCT116 effect by mitochondrial targeting function.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "obtained", "CDs", "had", "an", "anti-human", ...
PMC11694625	After a final wash with PBS for 2–3 times, the cells were observed immediately under an inverted fluorescence microscope.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "a", "final", ...
PMC11611077	In group 3, prestin was not considered to be expressed in the CHO cell membrane.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "In", "group", "3", ",", "prestin", "was", ...
PMC11754094	The output quantifies CRISPR-treated large deletions and small indels, and provides read alignment results.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "output", "quantifies", "CRISPR-treated", "large", "deletio...
PMC11754436	The mRNAs were predicted using miRDB, TargetScan and mirTarBase, and all genes are shown in the turquoise module.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mRNAs", "were", ...
PMC10656496	Plates were incubated in an Incucyte SX5 where brightfield and fluorescent scans were taken every 24 h. Drug screening with cells in log phase was conducted using phamocokinetic guided dose levels when available and high-throughput cell viability assays as previously described.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10048572	The authors explained this result by the fact that the initial tumor is heterogeneous and that highly metastatic variants of tumor cells already exist in the parental population.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Cytokine release profile revealed a higher production of IL-6, IL-17A, sFasL and IFNg by CAR-NKAE (Fig.2C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cytokine", "release", "profi...
PMC10654497	Furthermore, we chose three SFRGs (SLC16A1, SLC3A2, and SLC11A2) using the Lasso–Cox technique for regression analysis and developed a reliable risk model to divide patients with LUAD into high- and low-risk groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Adult patients were treated with GMALL like protocol.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Adult", "patients", "were", "treated", "with", "GMALL", "like", "protocol", "." ] } ]
PMC11789597	In addition, surface CD38 was increased by CAV1 knockdown in these MM cells (Figure S3I, Supporting Information).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ...
PMC11783017	ns: no significance, ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001, compared with Control group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ns", ":", "no", ...
PMC11628309	In contrast, RA treatment increases these markers compared to the undifferentiated state, but to a lesser extent than staurosporine.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "contrast", ...
PMC11782508	The functional groups of azurin were analyzed using FTIR spectroscopy, providing a valuable model for studying proteins with characteristic β-barrel structures.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "funct...
PMC11694625	White solid gradually precipitated during the stirring process.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "White", "solid", "gradually", "precipitated", "during", "the", "stirring", "process", "." ] } ]
PMC11773391	The inhibition rate and IC50 were calculated utilising SPSS software (version 26.0, SPSS Inc., Chicago, IL, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC11541241	Further studies revealed that FKBP12 forms a ternary complex with rapamycin and the FKBP12‐rapamycin binding (FRB) domain of TOR to repress its activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11687167	The CD8 + T cells typically differentiate into CTLs upon activation and specifically kill target cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "CD8", "+", "T", "cells", "typically", "di...
PMC11607638	Fura‐2 AM (#1051B) was from Dakewe (Beijing, China).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fura‐2", "AM", "(", "#", "1051B", ")", "was", "from", "Dak...
PMC11792888	No. 9101, 1:1000), caspase-3 (D3R6Y) (CST, Cat.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No.", "9101", ",", "1:1000", ")", ",", "caspase-3", "(", "...
PMC4443654	However, overall the complexity of TAD boundaries (measured as the number of strongly enriched features) is notably higher in H1 hESC than in the other two, more differentiated, cell types (Figure 6), involving large increases in the binding of sequence specific factors such as SP1 and JUND.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9503669	DQBS also inhibited the replication of HIV-1 NL4-3 chimeras expressing Nef alleles representative of all M-group HIV-1 clades with similar nanomolar potency but did not affect the replication of Nef-defective HIV-1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	4 out of 14 patients died due to aGVHD(28.6% of total, 1 in intestine, 1 in lung and liver, 1in lung and 1 in skin, intestine, and liver).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7433824	The xCELLigence system was used to examine cell growth when different concentrations of P4 (20, 50, 100, and 300 µM) was administered.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11638255	This model has been widely used to study anti-GD2-directed treatments including combination therapies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "model", "has", "been", "widely", "used", "to", "study", "anti...
PMC11779605	Estimated sample components.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "Estimated", "sample", "components", "." ] } ]
PMC11411131	The SECIS was derived from SelN. SelN cDNAs displayed a single-band signal.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "SECIS", "was", "derived", "from", "SelN.", "SelN", "cDNAs", "displayed", ...
PMC11258145	Following cooling, the absorbance at 532 nm was measured using an MDA molar extinction coefficient of 155/mM/cm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Following", "cooling", ",", "the", "ab...
PMC9429973	Patients with IE had an average age of 57.2 years (24 – 83 years), 57 (78%) were men and 8 (11%) had a positive family history.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9019892	In addition, nintedanib increased the phosphorylation of H2AX in the primary tumour cells derived from KIT‐V559D and KIT‐K642E GIST patients, which suggested that nintedanib could induce apoptosis in part through DNA double‐strand breaks (Fig. S6).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11767725	S. aureus lipases further degrade lipids into irritant free fatty acids, aggravating keratinocyte dysfunction and inflammation .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "S.", "aureus", "lipases", "further", "degrade", ...
PMC9621239	β-actin was used as a loading control.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "β-actin", "was", "used", "as", "a", "loading", "control", "." ] } ]
PMC6379402	We biologically validate that they have a role in cancer by knockdown experiments followed by cell viability assays.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "biologically", "validate", "that", ...
PMC9429973	COVID-19 vaccination was a protective factor for mortality, even in this population with humoral immunity impairment. -	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "COVID-19", "vaccination", "was", "a", ...
PMC11637276	After 5 h and 45 min, Hoechst-33342 was spiked into a final concentration of 0.5 to 1 μg/ml.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "5", "h", "and", "4...
PMC11441402	The grey dashed line (A-B) indicates y = x linearity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "grey", "dashed", "line", "(", "A-B", ")", "indicates", "y", "=", ...
PMC11719944	Furthermore, there is also a significant decrease in IL-17—a pro-inflammatory cytokine—in patients with T1D, which is consistent with the increase in exhausted CD8+ T cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9325715	In turn, it was shown that both native human LTF and its fragments can take part in directed transport of the Fe to the brush-border membrane by binding to lactoferrin receptors, which can be considered as a specific carrier-mediated iron uptake mechanism.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11507371	Then, intensities per cell were calculated, and the nucleus-to-cytoplasm ratios were formed to analyse the translocation of the targeted proteins (NF-κB, Nrf2, Keap1, IκBα).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11666785	2Correlation study for Dendra2-Actin transfected cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "2Correlation", "study", "for", "Dendra2-Actin", "transfected", "cells", "." ] } ]
PMC10850553	The tag count of C5AR1 from acquired data sets is shown.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "tag", "count", "of", "C5AR1", "from", "acquired", "data", "sets", "is", ...
PMC11590005	The target popu-lation was Brazilian dental students enrolled in the countrys public and private higher dental education system, with no restrictions on age, gender, skin co-lour, ethnicity, or socioeconomic background.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The ITP and AIHA commonly develop simultaneously, or sequentially within at least 8 months apart.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "ITP", "and", "AIHA", "commonly", "develop", ...
PMC11678448	Following the removal of low-quality reads and joint sequences, 241 million clean reads remained.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Following", "the", "removal", "of", "low-quality", "reads", ...
PMC11155445	All compounds showed poor activity against B. cereus with minimal cell inhibition of about 1–3%.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "compounds", "showed", "poor", "activity", "agai...
PMC9429973	90% of patients in both groups required biological therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "90", "%", "of", "patients", "in", "both", "groups", "required", "biological", "therapy", "...
PMC11627133	Scale bar, 10 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", ",", "10", "μm", "." ] } ]
PMC11687663	Post-simulation, the results were meticulously analyzed, focusing on binding affinity and the mode of interaction between ligands and the protein.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Post-simulation", ...
PMC9429973	combined, 9 non-CNS).	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "combined", ",", "9", "non-CNS", ")", "." ] } ]
PMC10154881	E.G‐7/N4 bearing mice were intratumorally treated with saline or rMV‐SLAMblind, twice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "E.G‐7/N4", "bearing", "mice", "were", "intratumorally", "treated", "with", "saline", ...
PMC9429973	Image: Summary/Conclusion: This study reported that STAG2 mutations were recurrent in GATA2 deficiency clonal hematopoiesis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Image", ":", "Summary/Conclusion", ":", "This", ...
PMC11534035	When treated with 5 μM of G36, the A431 tumor sphere size significantly decreased relative to control cells (M=34,672±3,645 px vs. control; p<0.01).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11659921	To investigate the significance of angiogenesis‐related and stemness‐related genes in OV, we collected relevant genes from Genecard website, applying an inclusion criterion of a score greater than 1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9503669	While these and other agents successfully induce HIV-1 expression in the presence of cART, neither treatment alone reduced the viral reservoir.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "While", "the...
PMC10073922	The invaded cells were then fixed with methanol, stained, and counted.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "invaded", "cells", "were", "then", "fixed", "with", "methanol", ...
PMC11768927	Furthermore, in vivo studies indicated that rVSV-ΔM51 not only inhibited tumor growth but also prolonged survival in murine models of PDA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ...
PMC11724582	These findings suggest that CAFs increase the tolerance of NSCLC cells to almonertinib and induce almonertinib resistance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "findings", "suggest", "that", "CAFs", ...
PMC4270159	b. Harvest cells from the tissue culture plate using 1× trypsin–EDTA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "b.", "Harvest", "cells", "from", "the", "tissue", "culture", "pl...
PMC11371627	It is unknown whether pathogenic variants in XK impact on the formation or stability of this disulphide bond.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "unknown", "whether", "path...
PMC10440586	YTZ, YCL, SW and EFS conceived the study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "YTZ", ",", "YCL", ",", "SW", "and", "EFS", "conceived", "the", "study", "." ] } ]
PMC11473843	Statistical analyses were done using one-way ANOVA; n, number of biologically independent samples.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "analyses", "were", "done", "using", "one-way", ...

PMC11222184

SH-SY5Y cells were exposed to various concentrations of Hsp90 inhibitors for 24 h and 48 h. There was a dose- and time-dependent decrease in SH-SY5Y cell viability against HSP90 inhibitors.

[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "...

PMC9429973

Patients who were refractory/relapsed <12 months from 1 line (1L) therapy, eligible for a stem cell transplant (SCT) at initial relapse/refractory, had an ECOG performance score of 0-1 and had no history of hepatitis B or C or CNS events were studied.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11755467

Due to the absence of any biological effect of nalidixic acid on HIV-1 replication, we continued to study the impact of Enoxacin.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Due", ...

PMC11656657

The circulating human T-cells were evaluated periodically in mice peripheral blood.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "circulating", "human", "T-cells", "were", "evaluated", "periodically", "in", "mice",...

PMC5925824

3LY3300054 enhances T cell activation in vitro.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "3LY3300054", "enhances", "T", "cell", "activation", "in", "vitro", "." ] } ]

PMC9429973

Mechanismly, Asxl1 deletion in Jak2 HSPCs leads to enhancer activation of polycomb group (PcG) target genes, such as Egr1 (Figure 1H).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC3675084

The DNA content was analyzed based on propidium iodide fluorescence using FACSCalibur equipped with a 488 nm laser and a 610±20 nm band-pass filter.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11788920

Therefore, the Cy3 signal correlates with the quantity of all transcription events, while the Cy5 signal correlates with the quantity of events that reach the end, meaning culmination in a full-length RNA product.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7917457

The numbers of mice in each group were 8−10.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "numbers", "of", "mice", "in", "each", "group", "were", "8−10", "." ] } ]

PMC11754784

A widely existed bottleneck of microenvironment-confined DNA computing strategies is the slow computing speed and weak output signal.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "widely", "existed", "bottleneck", ...

PMC7553912

In the present study, OSM induced the expressions of crystal-binding molecules, including OPN, ANXA1, and ANXA2, in the cultured renal fibroblasts.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC10936243

In the second phase, the qualitative semi-structured interview was used to help explain the quantitative results in more depth, so as to understand the context in which these barriers were encountered; such barriers having been indicated in the first phase of this study.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8073654

Trans-3-(3′4′-dimethoxyphenyl)-4-[(E)-3′′,4′′-dimethoxystyryl]cyclohex-1-ene (11), and cis-3-(3′4′-dimethoxyphenyl)-4-[(E)-3′′,4′′-dimethoxystyryl]cyclohex-1-ene (4) have exerted neurotrophic effects by inducing neurite sprouting in PC12 cells and triggering neurogenesis and neurite growth and protection in primary cul...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", ...

PMC9429973

The most common adverse events (≥10% occurrence) were neutropenia (n=13), thrombocytopenia (n=12), asthenia (n=9), anemia (n=7), rash (n=4), diarrhea (n=3), dizziness (n=3), general physical health deterioration (n=3), muscle spasms (n=3), peripheral oedema (n=3), pyrexia (n=3).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11747467

The DEGs were further screened using the filtering standard of |logFC| > 1 and the adjusted p-value (adj.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "DEGs", "were", "further", ...

PMC11626627

By conducting an analysis of TWIST1 in the TIMER database , we found a differential expression of TWIST1 in various solid tumors, with high expression in Kidney Clear Cell Carcinoma (KIRC) (Fig. 2A, B).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7602170

Various inhibitory drugs targeting different parts of the PI3K/AKT/mTOR pathway are currently being investigated in phase Ι and phase ΙΙ clinical trials.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Various", "i...

PMC11321678

Interestingly, HOX family genes which relate to embryonic development, morphogenesis, and differentiation, are associated with subgroup‐specific CCAN (Figure S5B, Supporting Information).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9046263

We performed a correlation and clustering analysis of HERV expression in our cell lines of interest, as shown in Fig. 1B.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "perfor...

PMC3995603

Chronic use can also be associated with significant adverse effects.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Chronic", "use", "can", "also", "be", "associated", "with", "significant", "adverse", "effects",...

PMC11768927

A promising approach to enhance oncolytic selectivity and reduce neurotoxicity involves the use of recombinant VSV encoding the IFN-β gene (VSV-IFNβ).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", ...

PMC9856122

For example, clinicians investigated the effects of BBR (NCT04479202) on intestinal function, serum concentrations of inflammatory biomarkers, and organ function in severe SARS-CoV-2-infected patients in a prospective randomized controlled clinical trial supported by the Chinese medical association.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10024132

The findings validate our previous study , while further showing that the combination of γ9δ2 T cells and blinatumomab can clear xenografted ALL cells from bone marrow.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11438317

This way, we found FYB, HPK-1, Vav, SLP76, LCK, HS1, Pyk2, and Syk in LP-DACS precipitates (Fig. 1C).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11643491

The entrapment efficiency of paclitaxel within the particles was 32.5% as determined by HPLC (Figure 5C).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "entrapment", "efficiency", ...

PMC9429973

Patients with the underlying diagnosis of hematologic malignancies were included.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "with", "the", "underlying", "diagnosis", "of", "hematologic", "malignancies", "were", ...

PMC11453018

In proliferative ES cells, the EWS::FLI1/P300 complex induces LMNB1 by binding to its enhancer motif containing 14 GGAA repeats.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "proliferative", "ES", ...

PMC9429973

Vamifeport inhibits ferroportin-mediated iron export into plasma and has been shown to decrease serum iron and transferrin saturation (TSAT) levels in relevant animal disease models and healthy volunteers.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11591794

With their combination, the dose of chemotherapy agent used could be lower and effective anticancer properties would be revealed with GA, which has antioxidant properties.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11194678

The same sample of STAU1 WT were used in evaluating STAU1 LLPS disruption with salt or 1,6 HD. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "same", "sample", "of", ...

PMC9429973

In the H12O, median OS was 45.1, 45.2, 65.1 months and not reached for the 1999-2009, 2010-2014 and 2015-2019 periods, respectively (p=0.001).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8633974

b-c) Transmission electron microscopy images of the CRISPR-Cas9 loaded LNPs showed monodispersed spherical morphology, including a particle surface corona.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "b-c", ")", "Trans...

PMC4270159

c. Incubate for ∼1 min.

[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "c.", "Incubate", "for", "∼1", "min", "." ] } ]

PMC11736898

However, reduction of VDR expression levels, and/or reduction of VDR nuclear localization (which may be related to levels of vitamin D present [64–66]), may render keloid cells resistant to the therapeutic effects of vitamin D or other anti-keloid interventions.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10114490

Epidermal growth factor (EGF) and transforming growth factor beta (TGFβ) were purchased to PeproTech.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Epidermal", "growth", "factor", "(", "...

PMC11628904

Full fin regrowth, indicating successful wound healing, occurs at roughly 72 hpb (Figure 1B).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Full", "fin", "regrowth", ",", "indica...

PMC3164356

Consistent with this, a homolog to this gene is found in the CHO-K1 genome but is not expressed (Fig. 3b,i).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...

PMC11543935

The alcian blue staining (Fig. 5A) further showed no optical cell polarization is present throughout the section indicating a successful nutrient supply throughout the gel.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11564322

In all the studied cell lines, the VVGPGA peptide co-treatment with the c-SRC inhibitor I increased the KI67 mRNA expression, compared to the control (by 24.01% in the HL-60 cell line, by 36.62% in the K562 cell line, and by 26.99% in the MEG-A2 cell line) (Fig. 2A–C).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11562028

The obtained CDs had an anti-human colon cancer cell HCT116 effect by mitochondrial targeting function.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "obtained", "CDs", "had", "an", "anti-human", ...

PMC11694625

After a final wash with PBS for 2–3 times, the cells were observed immediately under an inverted fluorescence microscope.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "a", "final", ...

PMC11611077

In group 3, prestin was not considered to be expressed in the CHO cell membrane.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "In", "group", "3", ",", "prestin", "was", ...

PMC11754094

The output quantifies CRISPR-treated large deletions and small indels, and provides read alignment results.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "output", "quantifies", "CRISPR-treated", "large", "deletio...

PMC11754436

The mRNAs were predicted using miRDB, TargetScan and mirTarBase, and all genes are shown in the turquoise module.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mRNAs", "were", ...

PMC10656496

Plates were incubated in an Incucyte SX5 where brightfield and fluorescent scans were taken every 24 h. Drug screening with cells in log phase was conducted using phamocokinetic guided dose levels when available and high-throughput cell viability assays as previously described.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10048572

The authors explained this result by the fact that the initial tumor is heterogeneous and that highly metastatic variants of tumor cells already exist in the parental population.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Cytokine release profile revealed a higher production of IL-6, IL-17A, sFasL and IFNg by CAR-NKAE (Fig.2C).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cytokine", "release", "profi...

PMC10654497

Furthermore, we chose three SFRGs (SLC16A1, SLC3A2, and SLC11A2) using the Lasso–Cox technique for regression analysis and developed a reliable risk model to divide patients with LUAD into high- and low-risk groups.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Adult patients were treated with GMALL like protocol.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Adult", "patients", "were", "treated", "with", "GMALL", "like", "protocol", "." ] } ]

PMC11789597

In addition, surface CD38 was increased by CAV1 knockdown in these MM cells (Figure S3I, Supporting Information).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ...

PMC11783017

ns: no significance, ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001, compared with Control group.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ns", ":", "no", ...

PMC11628309

In contrast, RA treatment increases these markers compared to the undifferentiated state, but to a lesser extent than staurosporine.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "contrast", ...

PMC11782508

The functional groups of azurin were analyzed using FTIR spectroscopy, providing a valuable model for studying proteins with characteristic β-barrel structures.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "funct...

PMC11694625

White solid gradually precipitated during the stirring process.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "White", "solid", "gradually", "precipitated", "during", "the", "stirring", "process", "." ] } ]

PMC11773391

The inhibition rate and IC50 were calculated utilising SPSS software (version 26.0, SPSS Inc., Chicago, IL, USA).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...

PMC11541241

Further studies revealed that FKBP12 forms a ternary complex with rapamycin and the FKBP12‐rapamycin binding (FRB) domain of TOR to repress its activity.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC11687167

The CD8 + T cells typically differentiate into CTLs upon activation and specifically kill target cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "CD8", "+", "T", "cells", "typically", "di...

PMC11607638

Fura‐2 AM (#1051B) was from Dakewe (Beijing, China).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fura‐2", "AM", "(", "#", "1051B", ")", "was", "from", "Dak...

PMC11792888

No. 9101, 1:1000), caspase-3 (D3R6Y) (CST, Cat.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No.", "9101", ",", "1:1000", ")", ",", "caspase-3", "(", "...

PMC4443654

However, overall the complexity of TAD boundaries (measured as the number of strongly enriched features) is notably higher in H1 hESC than in the other two, more differentiated, cell types (Figure 6), involving large increases in the binding of sequence specific factors such as SP1 and JUND.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9503669

DQBS also inhibited the replication of HIV-1 NL4-3 chimeras expressing Nef alleles representative of all M-group HIV-1 clades with similar nanomolar potency but did not affect the replication of Nef-defective HIV-1.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

4 out of 14 patients died due to aGVHD(28.6% of total, 1 in intestine, 1 in lung and liver, 1in lung and 1 in skin, intestine, and liver).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7433824

The xCELLigence system was used to examine cell growth when different concentrations of P4 (20, 50, 100, and 300 µM) was administered.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11638255

This model has been widely used to study anti-GD2-directed treatments including combination therapies.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "model", "has", "been", "widely", "used", "to", "study", "anti...

PMC11779605

Estimated sample components.

[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "Estimated", "sample", "components", "." ] } ]

PMC11411131

The SECIS was derived from SelN. SelN cDNAs displayed a single-band signal.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "SECIS", "was", "derived", "from", "SelN.", "SelN", "cDNAs", "displayed", ...

PMC11258145

Following cooling, the absorbance at 532 nm was measured using an MDA molar extinction coefficient of 155/mM/cm.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Following", "cooling", ",", "the", "ab...

PMC9429973

Patients with IE had an average age of 57.2 years (24 – 83 years), 57 (78%) were men and 8 (11%) had a positive family history.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9019892

In addition, nintedanib increased the phosphorylation of H2AX in the primary tumour cells derived from KIT‐V559D and KIT‐K642E GIST patients, which suggested that nintedanib could induce apoptosis in part through DNA double‐strand breaks (Fig. S6).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11767725

S. aureus lipases further degrade lipids into irritant free fatty acids, aggravating keratinocyte dysfunction and inflammation .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "S.", "aureus", "lipases", "further", "degrade", ...

PMC9621239

β-actin was used as a loading control.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "β-actin", "was", "used", "as", "a", "loading", "control", "." ] } ]

PMC6379402

We biologically validate that they have a role in cancer by knockdown experiments followed by cell viability assays.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "biologically", "validate", "that", ...

PMC9429973

COVID-19 vaccination was a protective factor for mortality, even in this population with humoral immunity impairment. -

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "COVID-19", "vaccination", "was", "a", ...

PMC11637276

After 5 h and 45 min, Hoechst-33342 was spiked into a final concentration of 0.5 to 1 μg/ml.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "5", "h", "and", "4...

PMC11441402

The grey dashed line (A-B) indicates y = x linearity.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "grey", "dashed", "line", "(", "A-B", ")", "indicates", "y", "=", ...

PMC11719944

Furthermore, there is also a significant decrease in IL-17—a pro-inflammatory cytokine—in patients with T1D, which is consistent with the increase in exhausted CD8+ T cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9325715

In turn, it was shown that both native human LTF and its fragments can take part in directed transport of the Fe to the brush-border membrane by binding to lactoferrin receptors, which can be considered as a specific carrier-mediated iron uptake mechanism.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11507371

Then, intensities per cell were calculated, and the nucleus-to-cytoplasm ratios were formed to analyse the translocation of the targeted proteins (NF-κB, Nrf2, Keap1, IκBα).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11666785

2Correlation study for Dendra2-Actin transfected cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "2Correlation", "study", "for", "Dendra2-Actin", "transfected", "cells", "." ] } ]

PMC10850553

The tag count of C5AR1 from acquired data sets is shown.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "tag", "count", "of", "C5AR1", "from", "acquired", "data", "sets", "is", ...

PMC11590005

The target popu-lation was Brazilian dental students enrolled in the countrys public and private higher dental education system, with no restrictions on age, gender, skin co-lour, ethnicity, or socioeconomic background.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

The ITP and AIHA commonly develop simultaneously, or sequentially within at least 8 months apart.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "ITP", "and", "AIHA", "commonly", "develop", ...

PMC11678448

Following the removal of low-quality reads and joint sequences, 241 million clean reads remained.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Following", "the", "removal", "of", "low-quality", "reads", ...

PMC11155445

All compounds showed poor activity against B. cereus with minimal cell inhibition of about 1–3%.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "compounds", "showed", "poor", "activity", "agai...

PMC9429973

90% of patients in both groups required biological therapy.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "90", "%", "of", "patients", "in", "both", "groups", "required", "biological", "therapy", "...

PMC11627133

Scale bar, 10 μm.

[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", ",", "10", "μm", "." ] } ]

PMC11687663

Post-simulation, the results were meticulously analyzed, focusing on binding affinity and the mode of interaction between ligands and the protein.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Post-simulation", ...

PMC9429973

combined, 9 non-CNS).

[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "combined", ",", "9", "non-CNS", ")", "." ] } ]

PMC10154881

E.G‐7/N4 bearing mice were intratumorally treated with saline or rMV‐SLAMblind, twice.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "E.G‐7/N4", "bearing", "mice", "were", "intratumorally", "treated", "with", "saline", ...

PMC9429973

Image: Summary/Conclusion: This study reported that STAG2 mutations were recurrent in GATA2 deficiency clonal hematopoiesis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Image", ":", "Summary/Conclusion", ":", "This", ...

PMC11534035

When treated with 5 μM of G36, the A431 tumor sphere size significantly decreased relative to control cells (M=34,672±3,645 px vs. control; p<0.01).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11659921

To investigate the significance of angiogenesis‐related and stemness‐related genes in OV, we collected relevant genes from Genecard website, applying an inclusion criterion of a score greater than 1.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9503669

While these and other agents successfully induce HIV-1 expression in the presence of cART, neither treatment alone reduced the viral reservoir.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "While", "the...

PMC10073922

The invaded cells were then fixed with methanol, stained, and counted.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "invaded", "cells", "were", "then", "fixed", "with", "methanol", ...

PMC11768927

Furthermore, in vivo studies indicated that rVSV-ΔM51 not only inhibited tumor growth but also prolonged survival in murine models of PDA.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ...

PMC11724582

These findings suggest that CAFs increase the tolerance of NSCLC cells to almonertinib and induce almonertinib resistance.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "findings", "suggest", "that", "CAFs", ...

PMC4270159

b. Harvest cells from the tissue culture plate using 1× trypsin–EDTA.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "b.", "Harvest", "cells", "from", "the", "tissue", "culture", "pl...

PMC11371627

It is unknown whether pathogenic variants in XK impact on the formation or stability of this disulphide bond.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "unknown", "whether", "path...

PMC10440586

YTZ, YCL, SW and EFS conceived the study.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "YTZ", ",", "YCL", ",", "SW", "and", "EFS", "conceived", "the", "study", "." ] } ]

PMC11473843

Statistical analyses were done using one-way ANOVA; n, number of biologically independent samples.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "analyses", "were", "done", "using", "one-way", ...