Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
 Community
1
PMCID
string
Sentences
string
ner
list
PMC4395774
Two lentiviral constructs containing either the PGK promoter or an endogenous perforin promoter, PRFprom, were tested in this study.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Two", "lentiviral", ...
PMC11792090
Cell numbers in the blood of mice were normalized to those detected on the first day.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "numbers", "in", "the", "blood", "of", "m...
PMC11696576
The organic phase was washed with saturated aqueous NaHCO3 (20 mL) containing Na2S2O3 (9.50 mmol, 1.50 g), H2O (20 mL), dried over Na2SO4, and the organic solvent was evaporated under reduced pressure.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11641532
Tumor weight, measured at the end of the 30-day observation period, was significantly lower in the LV-h-HSD3B7 group compared to controls, suggesting that HSD3B7 silencing inhibits tumor growth in vivo (Figure 8C).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10197932
Furthermore, T-cell resistance to ROS is quite different, depending on the subset of lymphocytes following this order Teff > Treg > Tnaïve > Tmem 48.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11786767
Representative images showing the effects of RO-3306 treatment and Ki-67 knockdown are shown.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Representative", "images", "showing", "the", "effects", "of", "RO-3306", "t...
PMC11569208
Cells were lysed, miRNA was extracted at indicated timepoints, then probed for miR-30 and shRNA against ACP2 cassette expression. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "wer...
PMC8170755
Inline, a dose-dependent increase was observed at both gene and protein levels of Nm23-H1, a tumor suppressor in the cancerous cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Inline"...
PMC10047551
PD-L1 expression was previously shown to respond diversely to AZA treatment in different NSCLC cells .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PD-L1", "expression", "was", "previously", "shown", "to", "...
PMC10253973
Examples of such a protocol include half-sandwich ruthenium(II) complexes with human serum albumin (HSA) ; nitrosyl ruthenium(II) complex with bovine serum albumin (BSA) ; Ru(II)-arene complexes with DNA and BSA ; ruthenium(II) polypyridyl complexes with β-amyloid peptide and DNA cyclopentadienyl-; cyclooctaniedyl-base...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11321678
Our next question was to determine what mechanism underlies the high expression levels and high specificity of these NTR genes in certain subgroups.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Our", ...
PMC11344246
One way to improve this would be by utilising a multi-omics approach incorporating other types of information such as proteomics data (49).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11670407
h Representative TEM images of mitochondria in U2OS cells; the black arrows indicate mitochondria (scale bars: 5 μm and 500 nm).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC11746942
The data are presented as the mean ± SD. *
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "data", "are", "presented", "as", "the", "mean", "±", "SD", ".", "*" ] } ]
PMC9776316
We then set out to examine how cJUN is activated to drive XRCC4 transcription.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "then", "set", "out", "to", "examine", "how", "cJUN", ...
PMC11544122
Data represent the mean ± SEM from six independent experiments.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "represent", "the", "mean", "±", "SEM", "from", "six", "independent", "experiments", ...
PMC9429973
Adverse events (AEs) were graded as per the CTCAE v5.0 and responses assessed using the modified IWG 2006 criteria.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Adverse", "events", ...
PMC10454535
This illustrates the benefits of a synergistic drug application such as improving treatment effectiveness and requiring lower doses to minimize side effects in patients and reduce development of resistance.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
The diagnosis of SS is challenging and requires the integration of clinical presentation, histopathologic evaluation, and molecular studies.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "diagnosis", "of", ...
PMC11772585
The colony number was calculated.
[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "colony", "number", "was", "calculated", "." ] } ]
PMC11247842
Clinical mastitis (CM) incidence and somatic cell count (SCC) are commonly used phenotypes for genetic studies on mastitis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Clinical", "...
PMC11464609
After nucleic acid extraction from 23 FFPE samples (plus 5 non-FFPE controls) with confirmed viral infection, target enrichment was performed using the Comprehensive Viral Research Panel (Twist Bioscience).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10877303
Preliminary, the first drug candidate, Kihadanin B expressed six interactions with 3CL where one Pi-Alkyl bond at HIE194, two Conventional Hydrogen bonds at GLU169, and GLY146, and three Carbon Hydrogen bonds at MET168, HIS166, and CYS145 was observed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5363531
LKB1 null tumors are associated with clinical aggressiveness as well as with activation of SRC pathway, leading to the hypothesis that LKB1 loss promotes dependence upon this signaling pathway for cell migration .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11453018
Remarkably, alterations in the expression of P15 was observed as early as 4 h into the treatment (Supplementary Fig. 7A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Remarka...
PMC11697189
By Cox regression test, the value ranges are P < 0.0001, P < 0.001, P < 0.01, P < 0.05 and P < 0.1 respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11774251
A network pharmacology approach was employed to investigate the possible mechanism of Tan-I in treating psoriasis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "network", "pharmacology", "approach", "was", "emp...
PMC9966931
The diameter of the mycelium was measured on the sixth day.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "diameter", "of", "the", "mycelium", "was", "measured", "on", "the", "sixth", ...
PMC11088135
In brief, 5 μl Annexin V FITC and 10 μl PI were incubated with the cells for 15 min at 4 °C without light, and then the cells were determined by a FACSCalibur flow cytometer (BD Biosciences, USA), and the data were analyzed with Kaluza Analysis (version 2.1.1.20653; Beckman Coulter, Inc., USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11683240
For the binding analysis based on flow cytometry, PT was labeled with DyLight 488 NHS Ester (Thermo Fisher Scientific) according to the manufacturer’s protocol using the Zeba Spin Desalting Columns (7K MWCO, Thermo Fisher Scientific) to remove excess dye.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Additionally, myeloid cells derived from multiplex-edited hHSPCs also retained their function, demonstrating similar phagocytotic capacity and cytokine secretion compared to unedited control cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11770130
CerS2 knockdown upregulated the production of GDF15 protein in both control and Ntsr2 AKO primary adipocytes (Fig. 6b).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CerS2", "knockdown", "upregu...
PMC11545737
Shigella possesses a functional type III secretion system (T3SS), and recognition of the TS33 inner rod protein MxiI by Naip2 activates the NLRC4 inflammasome and caspase-1, leading to secretion of IL-1β and IL-18 and pyroptosis .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8382973
We next evaluated changes in the composition of the microbiota in rectal and vaginal samples in response to 2P23 gel rectovaginal application by bacterial 16S rRNA sequencing.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11682224
Clonal proliferation assay results for A431 and Colon16 cells; (B) Plot of statistical results of clone formation in A431 cells and Colon16 cells; (C) Results of CCK-8 assay on A431 cells and Colon16 cells.
[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "B-...
PMC11638764
Conversely, STAT5A expression was downregulated in the CER compartment, suggesting a potential translocation from the cytoplasm or membrane to the nucleus, where it may perform different functions ( Fig. 1F ).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9250505
In contrast, Olaparib treatment of CAOV2 cells did not alter the pBADS99/BAD ratio compared to vehicle-treated cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "contrast", ",", "Olaparib", ...
PMC10958426
For the inferred lineages, the stemness scores of cancer cells increase rapidly at the beginning of the pseudotime.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "the", "inferred", "lineage...
PMC11609529
Cell lysates were collected 72 h post-transduction, and western blotting was performed using an anti-MAML2 antibody (E).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "lysates", "were", ...
PMC11453018
To bridge this gap, we employed Cox regression analysis to examine the link between DEG expression and overall survival, identifying 74 genes significantly associated with patient survival (Wald p < 0.05), with the top 5 and bottom 5 hazard ratio genes presented for clarity (Fig. 4D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10507284
Furthermore, its reduction is related to increased immune cell infiltration, enhanced stroma, and elevation of immune activation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "its", ...
PMC9429973
Novel therapeutic strategies may reduce the minimal excess mortality encountered in contemporary diagnosed patients, particularly among the elderly.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Novel", "therapeutic", "strategies", ...
PMC11777207
Medium containing GM-CSF (20 ng/ml) was changed every 2 days, and the cells were harvested at day 7 by dissociating loosely adherent cells through agitation by pipetting.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11680049
The cytotoxicity index (IC50) was determined from dose-response curves using median effect analysis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cytotoxicity", "index", "(", "IC50", ")", "was", ...
PMC4369959
Preclinical evaluation against DMH-induced colon cancer in male Wistar rats showed that this bead has significantly better recession of the cancers compared to free ginger extract .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11625890
The mutant reduced cell death, increased processes involved in removal of unwanted components and promoted growth in brain cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mutant", "reduced", ...
PMC9429973
28 patients were female, 32 had aberrant TP53 (TP53 mut and/or del(17p)) and 40 were IGHV unmutated.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "28", "patients", ...
PMC9429973
The most common (≥5%) grade ≥3 adverse events (AEs) were lipase increase (18.8%, all asymptomatic elevations), thrombocytopenia (14.6%), and vomiting, ALT increase, abdominal pain, hypertension, anemia, neutropenia, and neutrophil count decrease (6.3% each).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10747139
Complexes 31 and 33 also showed higher activity than cisplatin in the HeLa cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Complexes", "31", "and", "33", "also", "showed", "higher", "acti...
PMC10976516
Late-stage NSCLC and almost always SCLC are nevertheless overwhelmingly linked with aggressive metastasis formation, which results in limited treatment options and therefore poor prognosis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11767793
An identical aliquot (10 mL, ≈50 µg/mL) of Au-PEI@NIST was centrifugally filtered (CFed) using Amicon Ultra 15 (regenerated cellulose membrane, molar mass cut off 50 kDa, MilliporeSigma, Bedford, MA) with a Beckman J2 centrifuge (3020× g or 5000 rpm, Beckman Coulter, Indianapolis, IN) for 20 min per each centrifugation...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11574029
In this study, we found that NOTCH3 was significantly upregulated and associated with poor prognosis in BLCA patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "this", "study", ",", ...
PMC11422497
Unpaired two-tailed Student’s t-test was applied to assess differences in cell viability, cell migration, invasion ability, cell apoptosis level, xenograft tumor volume, and xenograft tumor weight among various groups.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
We used the usual clinical procedures to collect a blood sample for Dry Blood Spot (DBS) to perform enzymatic, genetic, and biomarkers analyses.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Therefore, there is a constant need to find new prognostic markers, as well as markers that can be used as targets for therapeutics that could improve the treatment.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10719213
We did not perform power analysis for the sample size calculation; our study represents an exploratory analysis in 12 subject’s cells (4 controls and 8 MS patients).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10900886
Infection of these cells may contribute to systemic dissemination of EV-D68, which is an essential step toward the development of extra-respiratory complications.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Infecti...
PMC11757230
The samples were then transferred to 100 % ethanol, embedded in paraffin, sectioned into 3-μm slices, and stained with hematoxylin and eosin.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11365427
During phenylalanine deprivation, the activation of the ATF3–CHOP–DR5 pathway induced ERS-related cell death.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "During", "phenylalanine", "deprivation", ",", "the", "...
PMC11753435
Last, as an additional method to validate the optimized model’s ability to discriminate between peptide-protein pairs that bind and do not bind, we compare predicted CLIP scores on the ~1000 held-out true interacting pairs from our test dataset and the ~500,000 mismatched pairs that are assumed not to interact.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11684821
The vast majority of the study sample expressed either MR1*01 (71%) or MR1*02 (25%), which differ by encoding a histidine and an arginine at position 17, respectively, a position not thought to affect either antigen or TCR binding (15).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11767817
Since our results showed that the tested compounds retained their activity under hypoxic conditions, the experiments were performed under normoxic and hypoxic conditions to obtain more insight into the compound’s potential differences in action relating to oxygen concentration.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11544771
In all treatments, the subconfluent cells (around 70% confluence) were treated with indicated concentrations of CPX or PRE alone or in combination in the growth medium.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11127909
Cells were harvested and lysed.
[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "harvested", "and", "lysed", "." ] } ]
PMC9341513
CCND1 sits at the far right of a TAD which is bounded by convergent CTCF sites, starts just to the left of TPCN2, and ends between LTO1 and FGF19.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10565698
1 Expression and cyclic structural properties of circUSP10.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "1", "Expression", "and", "cyclic", "structural", "properties", "of", "circUSP10", "." ] } ]
PMC10047551
The methylation level of cg19724470 in the NSCLC tumors more closely resembled an on-off switch for PD-L1 expression, as cg19724470 methylation of the tumors with PD-L1 TPS ≥ 1%, in general, was lower compared to the methylation observed in tumors with PD-L1 TPS < 1%.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11400680
As we can see in Figure 6A, all three representative images at the Easy level achieved good segmentation results for both cells and nuclei.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9268183
Approximately 60% of the drugs used in therapies against cancer are based on chemicals of natural origin .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Approximately", "60", "%", "of", "the"...
PMC11648299
SERCA2 regulates desmosomal and adherens junction dynamics and defects in the ATP2A2 protein led to impaired keratinocyte differentiation and adhesion .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SERCA2", "regulates", "desmo...
PMC8481254
However, CA reduced the expression of Nudt9, SLC5A3, OGT, YAP, and O-GlcNAcylation in liver cancer cells cultured in HG.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11394386
Initially, we analyzed the HOTAIR promoter sequence using the Genome Browser, identifying multiple Wnt response elements (WRE) and hypoxia response elements (HRE).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11098378
Previous work has demonstrated that HopT1-2 antagonizes “nonhost resistance” defenses in plants by suppressing expression of nonhost 1 proteins required for this immune response .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Continuous variables were dichotomized at optimal cut-off points using receiving operating characteristic curves.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Continuous", "variables", "were", "dichotomized", "at", "optimal", "cut-off", ...
PMC9429973
Changes from baseline are presented as least-square (LS) mean ANCOVA % change ±standard error of the mean for %-predicted DLCO, spleen volume, liver volume, platelet count, liver function, and lipid profile.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11659734
The human population encounters BPA through various routes and sources, with diet identified as the main source of exposure.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "human", "population",...
PMC11409031
Conduct correlation analysis among the different gene modules. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Conduct", "correlation", "analysis", "among", "the", "different", "gene", "modules", ".", "(" ] } ]
PMC10538569
Using live-cell imaging, we observed that when GPI-GFP or GPI-scFv X5 transduced T cells are co-cultured with iDCs, GPI-anchored proteins enrich in contact zones and subsequently migrate from T cells into DCs, suggesting that transferred GPI-scFv X5 interferes with HIV-1 infection of iDCs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Our results support the use of D-Rd in transplant-ineligible patients with NDMM.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Our", "results", "support", "the", "use", "of", "D-Rd", "in", "transplant-inelig...
PMC11756514
As we illustrated here, the production of CP by S. aureus is highly dependent on the bacterial culture conditions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "we", "illustrated", ...
PMC11718031
Figure 1 shows a schematic design of the overall outline of this study.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Figure", "1", "shows", "a", "schematic", "design", "of", "the", "over...
PMC9429973
Patients who were not eligible for the study were excluded.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "who", "were", "not", "eligible", "for", "the", "study", "were", "excluded", "....
PMC11733919
At selected time points, cells were stained using 0.4% trypan blue solution, and the levels of live (nonstained cells, %) and necrotic (permanently stained cells, %) were calculated using TC10 Automated Cell Counter (Bio-Rad, Hercules, CA, USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11536589
The cell viabilities of parental PDAC cells treated with different concentration of PKF-118-310 (10 nM, 100 nM, 200 nM, and 500 nM) for 48 h. (C) The cell viabilities of MRTX1133-resistant PDAC cells treated with different concentration of PKF-118-310 (10 nM, 100 nM, 200 nM, and 500 nM) for 48 h. (D) The cell prolifera...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10988808
KEGG pathway analysis of these differential genes suggested that CCDC25 may affect protein digestion and absorption, ECM-receptor interaction and the Hippo pathway, among others.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973
We started empiric treatment with CsA at an initial dose of 1.5mg/kg twice daily in these pts and the median time to reach>500 ANC was 5 days (4-9).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6461034
To explore whether a kinase with a low INKA score does not show a response to the corresponding drug, we selected ABL that ranked low in both PDXs and organoids of CRC0177 and CRC0254.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8469018
Next, cells were mixed with solution 5 (containing all three dyes) at a 19/1 ratio.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Next", ",", "cells", "were", "mixed", ...
PMC11394730
Furthermore, emodin was found to induce apoptosis through the mitochondrial route based on its impact on the levels of Bax/Bcl-2 protein expression and mitochondrial membrane potential.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11394386
This inhibitor targets the 5’ domain responsible for interaction with EZH2, resulting in the inhibition of metastasis in an orthotopic breast cancer model using cell lines .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11704834
Lentivirus-containing culture medium was used immediately, or stored at 4˚C. Lentiviral transduction of the parental A549 cell line was performed in a 24-well plate using a 0.5 multiplicity of infection followed by incubation at 37˚C in a humidified incubator with 5% CO2 for 48 h prior to selection and subsequent exper...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9473868
The synovial environment of RA is conducive to the survival of FLSs and inhibits its apoptosis, thereby participating in preventing its elimination.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC11683240
Therefore, PTS1 detection was analyzed in cells incubated at 37 °C, thus allowing cellular uptake of the toxin.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", ...
PMC11434983
Afterward, the supernatant was removed and the cells were exposed to 1 mg/mL MTT solution for 4 h at 37 °C.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Afterwa...
PMC11632064
The films were developed in a dark room by using an X-ray film processor.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "films", "were", "developed", "in", "a", "dark", "room", ...
PMC5716223
NGF (Promega, 10–100 ng/ml) was added to the GM or DM medium at the indicated time and replenished with media changes every 3 days.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11545737
Modulation of NF-κB activity modulation is achieved by the upregulation of Peroxisome proliferator-activated receptor-ɣ (PPAR-ɣ), which controls the availability of NF-κB in the nucleus .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10854447
A stirred solution of the appropriate N'-(((4-phenyl-1H-1,2,3-triazol-1-yl)acetyl)oxy)benzene-carboximidamide (6a–o) (0.78 mmole) in dry acetonitrile (20 mL) was refluxed overnight.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11489351
Then, 30 μl of the transfection reagent (Fugene HD) was added to the tube (3:1 Fugene HD to DNA ratio, μL:μg), mixed again by inverting the tube 4 to 5 times and then let incubate at room temperature for 15 min.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11222184
However, the dual role of the LIG4 enzyme in cancer has been mentioned in the literature.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "the", "dual", "role", "of",...