OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11240052	We evaluated the expression of these miRNAs in ovarian cancer patient tissues and found that miR-211-5p expression was significantly downregulated in cancer tissues (0.89±0.12) in comparison to normal adjacent tissue (3.5±0.22) (P<0.0001) (Figure 3a), and this downregulation was observed in the studied cell lines (Figu...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11129910	5 × 10 cells were injected orthotopically into the mammary fat pad.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "5", "×", "10", "cells", "were", "injected", "orthotopically", "into", "the", ...
PMC11367146	Then, these common genes were uploaded to STRING v11.5 to construct a protein-protein interaction (PPI) network.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", "these", "common", ...
PMC11545737	In human peripheral blood mononuclear cells (PBMCs), H. pylori induces NLRP3 inflammasome activation and IL-1β release .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "human", "peripheral", "bloo...
PMC9429973	F. Ong, T. M. Kadia, N. J. Short, M. Yilmaz, Y. Alvarado, S. Pierce, G. Garcia-Manero, C. DiNardo, G. Borthakur, M. Konopleva, N. Daver, H. Kantarjian, F. Ravandi Leukemia, The University of Texas MD Anderson Cancer Center, HOUSTON, United States of America Background: Efficacy of FLT3 inhibitors in patients (pts) with...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11672881	The alteration of several metabolic pathways has been shown to induce mitochondrial dysfunction in cancer cells, leading to decreased ATP production and increased oxidative stress, which can trigger apoptosis .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11502066	In addition, the pharmacological activity and selectivity of natural flavonoids may be further improved by diverse synthetic modifications.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", "the", ...
PMC8469018	The results of HPLC analysis are shown in Table 1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "results", "of", "HPLC", "analysis", "are", "shown", "in", "Table", "1", "." ] ...
PMC10006224	In contrast, cohesin-STAG1 binds chromatin and becomes stabilized at CTCF sites even under low NIPBL levels, but genome folding is severely impaired.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11283030	Cancer cells prefer DNL to exogenous uptake of lipid for rapid proliferation, which is called lipid metabolic reprogramming .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cancer", "cells", "prefer", "DNL"...
PMC9429973	In the context of leukemia, Golos et al., 2019 showed that the low expression of SLIT2 was associated with lower overall survival in adults with acute myeloid leukemia (AML).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8711270	HEK293 is commonly used in the production of viral vectors.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HEK293", "is", "commonly", "used", "in", "the", "production", "of", "viral", "vectors",...
PMC11082662	This supernatant underwent a sequential process involving membrane filtration to remove larger particles, followed by ultrafiltration and centrifugation to concentrate the extracellular vesicles.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	To better understand the biological changes induced on leukemic blast when exposed to M2 macrophages, we performed an RNA sequencing analysis comparing AML/APL samples at diagnosis to cells that were “trained” (48h) on M2-macrophages or on MS5 mesenchymal bone marrow stromal cells, as a control.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9243326	In this study, PacBio SMRT sequencing technology was used to successfully construct a high-quality transcript library of C. chinensis (26,312 unigenes with an average length of 2,572 bp), and the sequences were functionally annotated (including 24,151 Nr, 22,756 KEGG, 13,934 KOG, and 16,423 Swiss-Prot sequences) and st...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10998613	Statistical analyses were performed using GraphPad Prism (GraphPad Software).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "analyses", "were", "performed", "using", "GraphPad", "Prism", "(", "GraphPad...
PMC11748618	We generated a linear regression model of rs59784663-A-G dosage and performed a chi-square test against a linear regression model of rs72999655-A-G, rs7525622-G-A, and rs73004025-C-T in the ICGH combined cohort, controlling for sex and PC1 in both models.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11186948	In particular, we assessed in patient LCL HDAC2 intracellular localization, its expression and protein abundance, and eventually downstream effects of the variant on acetylation pattern and gene expression, which was investigated also by transcriptomic analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9960565	Dendrimers are monodisperse polymers possessing a central core around which the monomers are bound, layer upon layer (forming different generations), giving rise to structures of various sizes and molecular weights .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11525293	Actin was used as the loading control; one representative experiment is shown.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Actin", "was", "used", "as", "the", "loading", "control", ";", "one",...
PMC5386478	By western blot analysis, shown in Figure 2b, we confirmed silencing and evidenced an increase in PARP1 cleavage along with reduced AKT phosphorylation in cells silenced for TGM2-v1, when grown in hypoxia.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11594641	Quantitative reverse transcription–polymerase chain reaction (qRT-PCR) was carried out using the LightCycler RNA Amplification Kit SYBR Green I (Roche Diagnostics GmbH) according to the manufacturer’s instructions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10758402	Tumor size was monitored every other day using an electronic caliper, and their volumes were calculated using the formula (length × width)/2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11746948	h Cell viability in A375 cells with APT2 knockdown, infected with HA-APT2 lentivirus, followed by 48 h RSL3 treatment.	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "h", "Cell", ...
PMC10899471	We first explored the expression levels of BATF2 in human soft tissue sarcoma.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "first", "explored", "the", "expression", "levels", "of", "BATF2", ...
PMC11806106	From the resulting dataset, we generated concentration–response curves for various opioid agonists (Fig. 2B and Supplementary Fig. 2A–E) and subsequently determined the corresponding half-maximal effective concentration (EC50) values (Table 1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11472569	These survivin-enriched EVs significantly enhance the survival of serum-starved and PTX-treated fibroblasts and SKBR3 breast cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ "These", "survivin-enriched", "EVs", "significa...
PMC11670407	The samples were analyzed for potential interacting proteins via liquid chromatography‒mass spectrometry (LC‒MS) (Fig. 4a).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "samples", "were", "analyze...
PMC10656496	RNA, DNA, and miRNA from each of the osteosarcoma cell lines were isolated for expression, gene fusions, single nucleotide variations (SNVs), and copy number variation (CNV) analysis, using human osteoblasts as a control (Supplemental Fig. 1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11704834	Importantly, such cells develop EGFR-TKI resistance via acquisition of EMT phenotype (10).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Importantly", ",", "such", "cells", "develop", "EGFR-TKI", ...
PMC8992508	These compounds are chalcones variously substituted on rings A and B, and flavones with acetamido linker at position 2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "compounds", "are", ...
PMC11406030	The Compusyn software was utilized to generate Chou-Talalay plots (x axis: fractional activity [Fa], reflects the fraction of cellular viability affected by treatment relative to controls; y axis: combination index with <1, =1, and >1 indicating synergistic, additive, and antagonistic effects, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Only after the second dose, vaccine-induced CD8+ clonotypes show an enrichment of T-cell activation related genes, emphasizing the relevance of repeated vaccination.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11673902	After electroporation, the cell membrane can repair itself to some extent, allowing the cell to remain intact .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "electroporation", ",", "...
PMC11640115	In our study, an increase in peripheral blood lymphocyte count was also associated with therapeutic efficacy, suggesting that the peripheral blood lymphocyte count may reflect the immune response of the tumor microenvironment during ICI treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11047729	It has various biological activities, such as anti-cancer, antiviral, anti-parasitic, anti-inflammatory, anti-obesity, neuroprotective, nephroprotective, antioxidant, and wound-healing effects .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11321678	In total, we obtained 59015 cells after demultiplexing and removing doublets.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "total", ",", "we", "obtained", "59015", "cells", "after", "demultiplexing"...
PMC11461874	Beads were washed three times with wash buffer [20 mM HEPES-NaOH, 137 mM NaCl, 0.05% (v/v) Lubrol PX].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11708541	Tosylated 4-AP 30 created from 10 and 29 latter complexed with different metals and employed as antibacterial agents.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tosylated", "4-AP", "30", "created", "...
PMC11711663	Features described by the Imaging Biomarker Standardization Initiative (IBSI) were extracted in six families: shape, first-order, gray level co-occurrence matrix (GLCM), gray level run length matrix (GLRLM), grey level size zone matrix (GLSZM), gray level dependence matrix (GLDM) and neighborhood grey tone difference m...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Additionally, axillar lymph node biopsy was performed and pathohistological analysis showed sinus histiocytosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "axillar", "lymph", "node", "biopsy", "was", ...
PMC10758402	The studies involving humans were approved by The Global Tissue Consenting committee, Ottawa Hospital Research Institute.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "studies", "involving", "humans", "were", ...
PMC9429973	At a median follow-up of 291 days (range, 31 to 544), patients in the humanized group had a favorable progression-free survival (PFS) than those in the murinized (1-year PFS of 67.9% vs. 26.8%), although there was no statistical significance (p=0.08) due to the limited number of patients enrolled (Figure 1E-F).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10114490	Cytoplasm was defined using a “region growing” and “threshold” algorithm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cytoplasm", "was", "defined", "using", "a", "“", "region", "grow...
PMC3675084	Similarly, BPR0L075 treatment also induced concentration- and time-dependent cell cycle arrest in the G2/M phase in both the SKOV-3 and SKOV-3-TR cells, with high fraction of polyploid cells in SKOV-3-TR (Figure S1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "...
PMC11472639	Notably, we observed a 305% increase in NK-cells expressing CD38, the daratumumab target antigen, which might render NK-cells more susceptible to daratumumab-mediated fratricide – whereby NK-cells initiate ADCC against daratumumab-bound NK-cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9693627	Protein sequences of the complete human proteome provided by Uniprot were used for protein identification with Andromeda.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Protein", "sequences", "of", "the", "complete", ...
PMC3734024	Cultured B cells were then harvested, washed, and re-cultured at equal cell concentrations along with freshly-isolated CD19 B cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cultured", "B", "...
PMC11786156	The WST-1 assay was performed as previously described, with minor modifications.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "WST-1", "assay", "was", "performed", "as", "previously", "described", ","...
PMC10073922	No. CLL-185) was purchased from Pasture Institute, Iran.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No.", "CLL-185", ")", "was", "purchased", "from", "Pasture", "Institute", ",", "Iran", "."...
PMC9429973	Aims: To study the relationship between trough levels of generic dasatinib drugs with adverse events and molecular response in patients with Ph+ve ALL and CML.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC2196094	The active protease is a basic protein with a net charge of +10.6 (Arg + Lys = 27; Asp + Glu = 17). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11699178	The corrected results indicated the successful elimination of sample batch effects (Figure S2A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "corrected", "results", "indicated", "the", "successful", ...
PMC9436459	Moracenin D (95) was found to possess protective effects in dopamine-induced SH-SY5Y cells via the up-regulation of nurr1 and down-regulation of α-synuclein expressions .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC11047729	Nonetheless, the inhibition of telomerase via natural substances presents a promising strategy that could complement existing therapeutic approaches and enhance outcomes for leukemia patients in the future.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11321678	Second, matched normal cells were used as a reference to reduce false‐postive CNV events.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Second", ",", "matched", "normal", "cells", "were", "used",...
PMC6642070	We used UCSC Genome Browser (http://genome.ucsc.edu/) to obtain the human ENO3 genomic sequence.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "used", "UCSC", "Genome", "Browser", "(", "http://geno...
PMC10899471	The studies involving humans were approved by People’s Hospital of Xishui County.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "studies", "involving", "humans", "were", "approved", "by", "People",...
PMC9429973	DDR comprises a variety of mechanisms that protect genome integrity and repair damaged DNA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "DDR", "comprises", "a", "variety", "of", "mechanisms", "that", "...
PMC11781181	Therefore, we tested whether ferritinophagy is involved in SJS/TEN pathogenesis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "we", "tested", "whether", "ferritinophagy", "is", "involved", "in", ...
PMC9429973	Pre-specified equivalence criterion for the primary PK and PD parameters was 90% confidence interval (CI) for geometric means (GM) ratio within 0.80 to 1.25.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9341513	Figure 4D shows simulated 4C with viewpoints positioned at gene promoters (top four rows).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Figure", "4D", "shows", "simulated", "4C", "with", ...
PMC9429973	Aims: Here, we report DeepDecon, a deep neural network model that utilizes NGS RNAseq data to detect MRD of AML.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ...
PMC11638764	The results reveal distinct compartment-specific protein regulation, providing insight into p97/VCP’s cellular mechanisms and its potential for targeted therapeutic applications.(A) Titration curves of CB-5083 in HCT116 and HL-60 cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11471157	Asterisks indicate DFP. (	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Asterisks", "indicate", "DFP", ".", "(" ] } ]
PMC9429973	The persistence of leukemic stem cells (LSCs) is one of the reasons for relapse in AML.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "persistence", "of", "leukemic", ...
PMC11650848	By analysing the results in our longitudinal cohort, we also show a clear interaction with nutrition in determining methylation, and by extension transcription, at the ZFP57 locus, with nutrition having a smaller effect (approx.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11759543	Z-IETD-FMK and Z-VAD-FMK were purchased from TargetMol (MA, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Z-IETD-FMK", "and", "Z-VAD-FMK", "were", "purchased", "from", "TargetMol", "(", ...
PMC11089031	indicates P < 0.05; indicates P < 0.01; * indicates P < 0.001; **** indicates P < 0.0001 Since there are limited reports regarding ZNF692 target genes, we determined the genes whose expression correlated with ZNF692 expression and performed gene set enrichment analysis (GSEA) using those correlated genes to explor...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11297139	Consequently, it is plausible that oncogenic factors equipped with PrLDs and IDR might co-opt the BAF complex by directly interacting with ARID1A.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Consequ...
PMC11317131	A second plasmid called the accessory plasmid (AP), contained the attP site and the remaining portion of gIII (N1-C domains).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11283030	There are some weaknesses of this study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "are", "some", "weaknesses", "of", "this", "study", "." ] } ]
PMC5311252	For phenotype validation (flow cytometry and clonogenic assay) of miR-372 effects, stable hsa-mir-372-expressing cell lines and control cell lines were generated as follows.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9268183	Besides the extensive use of some of these drugs in therapies, such as those derived from the genus Taxus, a significant number of plants have revealed themselves as useful against cancer in recent years.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10092581	For almost all the silver(I) selenourea complexes, the metal content was rather different than that of the chalcogen and, in many cases, the intracellular amount of Se was significantly higher than that of Ag.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11610461	The connection of PSENEN expression level with WHO grade in KIRC tissues (G1: n = 6, G2: n = 10, G3: n = 5, G4: n = 2). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11734514	Wound was created through the monolayer using a sterile 200 μL pipette tip, and cells debris was removed by washing with PBS three times.8,9 Wound was observed under a microscope and measured to calculate the migration rate using the formula, including percentage wound healing for 24 and 48 hours = [(wound length at 0 ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The del5q was isolated in two RA cases as a del (5) (q13 q33) in a new diagnosed and a treated patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11789597	The GSEA was performed on omicstudio.cn.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "GSEA", "was", "performed", "on", "omicstudio.cn", "." ] } ]
PMC11791203	A sample volume of 1µL was injected into the system.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "sample", "volume", "of", "1µL", "was", "injected", "into", "the", "system", "." ]...
PMC10719213	Membranes were washed once with 2× SSC/0.1% SDS for 60 minutes, followed by 0.5× SSC/0.1% SDS for 60 minutes and finally in 0.1× SSC/0.1% SDS for 30 minutes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	We used our in-house data analysis pipeline for variant calling.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "used", "our", "in-house", "data", "analysis", "pipeline", "for", "variant", "calling", ...
PMC11683240	The remaining of each fraction was stored at −80 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "remaining", "of", "each", "fraction", "was", "stored", "at", "−80", "°", ...
PMC11594806	Another strategy involves combining DTX with the A2BR antagonist BAY606583, which inhibits the ERK signaling pathway and has shown antiproliferative effects on esophageal cancer cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC8701144	WF images were acquired for 30 Z planes and are displayed as maximum intensity projections rendered from all Z planes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "WF", "images", "were", ...
PMC11756907	The sample was topped up with an appropriate solvent (EtOH/DMSO) to a volume of 6 mL. The following suspensions were obtained: GO-2-ME in ethanol at a concentration of 0.25 mg/mL (based on the mass of graphene oxide).GO-2-ME in DMSO at a concentration of 0.25 mg/mL (based on the weight of graphene oxide).50 GO-2-ME in ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: This study aims to predict the risk factors that cause PRES in pediatric patients undergoing allo-HSCT and to evaluate the management of PRES.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11615828	Live‐cell imaging showed that Spike efficiently bound to the cell surface and then gradually moved to the interior of cells in ACE2‐positive HeLa cells (DMSO treated groups in Figure 7b,c, green curve; Video S29, upper panel, Supporting Information).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", ...
PMC11604830	The higher sensitivity of the CSI approach was tested with a linear coil to directly compare the two techniques.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "higher", "sensitivity", "o...
PMC11754784	Both type I and type II leakage of DNP3 in complex cell mixtures can be simulated computationally.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Both", "type", "I", "and", "type", "II", ...
PMC11012313	However, both historical and more recent data indicate that while there are some similarities between LMP2A and BCR signaling, downstream LMP2A signaling is unique in regards to the molecules that are constitutively activated in resting and transformed cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Sequencing 261 genes (N=42) identified mutations in JAK2 (45%), CALR (43%), and MPL (5%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	In addition, both RNAseq and WES identified additional genetic abnormalities not found by conventional approaches.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", "both", "RNAseq", "and", "...
PMC11453295	Importantly, analysis of mammary glands two-month post-MIND injections showed engraftment of human cells positive for cytokeratin-5 and lamin a/c.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Importantly", ",", "analysis...
PMC8427838	TMIGD1 expressing cells were selected with puromycin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TMIGD1", "expressing", "cells", "were", "selected", "with", "puromycin", "." ] } ]
PMC11782780	Previous studies have shown that the silencing of EBF3 promotes the progression of malignant tumors, but its impact on the stem-like phenotype of tumor cells remains unexplored.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10671321	In the motor system, it is essentially produced and secreted by muscle cells and preferentially accumulated in the extracellular matrix of the neuromuscular junction (NMJ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11297139	d The rank of transcription factor motifs overrepresented in the ARID1A LLPS-dependent upregulated cREs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "d", "The", "rank", "of", "transcription", "factor", "motifs", "o...
PMC9429973	The meta-analysis suggests that variants below a certain threshold, here empirically 10%, may in many cases be false-positive variants, in agreement with other reports involving WES in general, introduced by erroneous base calling, PCR errors, etc.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9910796	To evaluate the hypothesis that pEP84R itself may guide the localization of the core shell precursors we performed immunofluorescence (Fig 5) and immuno-EM (Fig 6) approaches on transfected cells expressing proteins pEP84R-Flag, pp220 and pp62 individually or in combination.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11240052

We evaluated the expression of these miRNAs in ovarian cancer patient tissues and found that miR-211-5p expression was significantly downregulated in cancer tissues (0.89±0.12) in comparison to normal adjacent tissue (3.5±0.22) (P<0.0001) (Figure 3a), and this downregulation was observed in the studied cell lines (Figu...

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PMC11129910

5 × 10 cells were injected orthotopically into the mammary fat pad.

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PMC11367146

Then, these common genes were uploaded to STRING v11.5 to construct a protein-protein interaction (PPI) network.

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PMC11545737

In human peripheral blood mononuclear cells (PBMCs), H. pylori induces NLRP3 inflammasome activation and IL-1β release .

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PMC9429973

F. Ong, T. M. Kadia, N. J. Short, M. Yilmaz, Y. Alvarado, S. Pierce, G. Garcia-Manero, C. DiNardo, G. Borthakur, M. Konopleva, N. Daver, H. Kantarjian, F. Ravandi Leukemia, The University of Texas MD Anderson Cancer Center, HOUSTON, United States of America Background: Efficacy of FLT3 inhibitors in patients (pts) with...

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PMC11672881

The alteration of several metabolic pathways has been shown to induce mitochondrial dysfunction in cancer cells, leading to decreased ATP production and increased oxidative stress, which can trigger apoptosis .

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PMC11502066

In addition, the pharmacological activity and selectivity of natural flavonoids may be further improved by diverse synthetic modifications.

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PMC8469018

The results of HPLC analysis are shown in Table 1.

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PMC10006224

In contrast, cohesin-STAG1 binds chromatin and becomes stabilized at CTCF sites even under low NIPBL levels, but genome folding is severely impaired.

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PMC11283030

Cancer cells prefer DNL to exogenous uptake of lipid for rapid proliferation, which is called lipid metabolic reprogramming .

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PMC9429973

In the context of leukemia, Golos et al., 2019 showed that the low expression of SLIT2 was associated with lower overall survival in adults with acute myeloid leukemia (AML).

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PMC8711270

HEK293 is commonly used in the production of viral vectors.

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PMC11082662

This supernatant underwent a sequential process involving membrane filtration to remove larger particles, followed by ultrafiltration and centrifugation to concentrate the extracellular vesicles.

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PMC9429973

To better understand the biological changes induced on leukemic blast when exposed to M2 macrophages, we performed an RNA sequencing analysis comparing AML/APL samples at diagnosis to cells that were “trained” (48h) on M2-macrophages or on MS5 mesenchymal bone marrow stromal cells, as a control.

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PMC9243326

In this study, PacBio SMRT sequencing technology was used to successfully construct a high-quality transcript library of C. chinensis (26,312 unigenes with an average length of 2,572 bp), and the sequences were functionally annotated (including 24,151 Nr, 22,756 KEGG, 13,934 KOG, and 16,423 Swiss-Prot sequences) and st...

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PMC10998613

Statistical analyses were performed using GraphPad Prism (GraphPad Software).

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PMC11748618

We generated a linear regression model of rs59784663-A-G dosage and performed a chi-square test against a linear regression model of rs72999655-A-G, rs7525622-G-A, and rs73004025-C-T in the ICGH combined cohort, controlling for sex and PC1 in both models.

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PMC11186948

In particular, we assessed in patient LCL HDAC2 intracellular localization, its expression and protein abundance, and eventually downstream effects of the variant on acetylation pattern and gene expression, which was investigated also by transcriptomic analysis.

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PMC9960565

Dendrimers are monodisperse polymers possessing a central core around which the monomers are bound, layer upon layer (forming different generations), giving rise to structures of various sizes and molecular weights .

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PMC11525293

Actin was used as the loading control; one representative experiment is shown.

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PMC5386478

By western blot analysis, shown in Figure 2b, we confirmed silencing and evidenced an increase in PARP1 cleavage along with reduced AKT phosphorylation in cells silenced for TGM2-v1, when grown in hypoxia.

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PMC11594641

Quantitative reverse transcription–polymerase chain reaction (qRT-PCR) was carried out using the LightCycler RNA Amplification Kit SYBR Green I (Roche Diagnostics GmbH) according to the manufacturer’s instructions.

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PMC10758402

Tumor size was monitored every other day using an electronic caliper, and their volumes were calculated using the formula (length × width)/2.

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PMC11746948

h Cell viability in A375 cells with APT2 knockdown, infected with HA-APT2 lentivirus, followed by 48 h RSL3 treatment.

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PMC10899471

We first explored the expression levels of BATF2 in human soft tissue sarcoma.

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PMC11806106

From the resulting dataset, we generated concentration–response curves for various opioid agonists (Fig. 2B and Supplementary Fig. 2A–E) and subsequently determined the corresponding half-maximal effective concentration (EC50) values (Table 1).

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PMC11472569

These survivin-enriched EVs significantly enhance the survival of serum-starved and PTX-treated fibroblasts and SKBR3 breast cancer cells.

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PMC11670407

The samples were analyzed for potential interacting proteins via liquid chromatography‒mass spectrometry (LC‒MS) (Fig. 4a).

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PMC10656496

RNA, DNA, and miRNA from each of the osteosarcoma cell lines were isolated for expression, gene fusions, single nucleotide variations (SNVs), and copy number variation (CNV) analysis, using human osteoblasts as a control (Supplemental Fig. 1).

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PMC11704834

Importantly, such cells develop EGFR-TKI resistance via acquisition of EMT phenotype (10).

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PMC8992508

These compounds are chalcones variously substituted on rings A and B, and flavones with acetamido linker at position 2.

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PMC11406030

The Compusyn software was utilized to generate Chou-Talalay plots (x axis: fractional activity [Fa], reflects the fraction of cellular viability affected by treatment relative to controls; y axis: combination index with <1, =1, and >1 indicating synergistic, additive, and antagonistic effects, respectively.

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PMC9429973

Only after the second dose, vaccine-induced CD8+ clonotypes show an enrichment of T-cell activation related genes, emphasizing the relevance of repeated vaccination.

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PMC11673902

After electroporation, the cell membrane can repair itself to some extent, allowing the cell to remain intact .

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PMC11640115

In our study, an increase in peripheral blood lymphocyte count was also associated with therapeutic efficacy, suggesting that the peripheral blood lymphocyte count may reflect the immune response of the tumor microenvironment during ICI treatment.

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PMC11047729

It has various biological activities, such as anti-cancer, antiviral, anti-parasitic, anti-inflammatory, anti-obesity, neuroprotective, nephroprotective, antioxidant, and wound-healing effects .

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PMC11321678

In total, we obtained 59015 cells after demultiplexing and removing doublets.

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PMC11461874

Beads were washed three times with wash buffer [20 mM HEPES-NaOH, 137 mM NaCl, 0.05% (v/v) Lubrol PX].

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PMC11708541

Tosylated 4-AP 30 created from 10 and 29 latter complexed with different metals and employed as antibacterial agents.

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PMC11711663

Features described by the Imaging Biomarker Standardization Initiative (IBSI) were extracted in six families: shape, first-order, gray level co-occurrence matrix (GLCM), gray level run length matrix (GLRLM), grey level size zone matrix (GLSZM), gray level dependence matrix (GLDM) and neighborhood grey tone difference m...

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PMC9429973

Additionally, axillar lymph node biopsy was performed and pathohistological analysis showed sinus histiocytosis.

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PMC10758402

The studies involving humans were approved by The Global Tissue Consenting committee, Ottawa Hospital Research Institute.

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PMC9429973

At a median follow-up of 291 days (range, 31 to 544), patients in the humanized group had a favorable progression-free survival (PFS) than those in the murinized (1-year PFS of 67.9% vs. 26.8%), although there was no statistical significance (p=0.08) due to the limited number of patients enrolled (Figure 1E-F).

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PMC10114490

Cytoplasm was defined using a “region growing” and “threshold” algorithm.

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PMC3675084

Similarly, BPR0L075 treatment also induced concentration- and time-dependent cell cycle arrest in the G2/M phase in both the SKOV-3 and SKOV-3-TR cells, with high fraction of polyploid cells in SKOV-3-TR (Figure S1).

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PMC11472639

Notably, we observed a 305% increase in NK-cells expressing CD38, the daratumumab target antigen, which might render NK-cells more susceptible to daratumumab-mediated fratricide – whereby NK-cells initiate ADCC against daratumumab-bound NK-cells.

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PMC9693627

Protein sequences of the complete human proteome provided by Uniprot were used for protein identification with Andromeda.

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PMC3734024

Cultured B cells were then harvested, washed, and re-cultured at equal cell concentrations along with freshly-isolated CD19 B cells.

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PMC11786156

The WST-1 assay was performed as previously described, with minor modifications.

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PMC10073922

No. CLL-185) was purchased from Pasture Institute, Iran.

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PMC9429973

Aims: To study the relationship between trough levels of generic dasatinib drugs with adverse events and molecular response in patients with Ph+ve ALL and CML.

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PMC2196094

The active protease is a basic protein with a net charge of +10.6 (Arg + Lys = 27; Asp + Glu = 17). (

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PMC11699178

The corrected results indicated the successful elimination of sample batch effects (Figure S2A).

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PMC9436459

Moracenin D (95) was found to possess protective effects in dopamine-induced SH-SY5Y cells via the up-regulation of nurr1 and down-regulation of α-synuclein expressions .

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PMC11047729

Nonetheless, the inhibition of telomerase via natural substances presents a promising strategy that could complement existing therapeutic approaches and enhance outcomes for leukemia patients in the future.

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PMC11321678

Second, matched normal cells were used as a reference to reduce false‐postive CNV events.

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PMC6642070

We used UCSC Genome Browser (http://genome.ucsc.edu/) to obtain the human ENO3 genomic sequence.

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PMC10899471

The studies involving humans were approved by People’s Hospital of Xishui County.

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PMC9429973

DDR comprises a variety of mechanisms that protect genome integrity and repair damaged DNA.

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PMC11781181

Therefore, we tested whether ferritinophagy is involved in SJS/TEN pathogenesis.

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PMC9429973

Pre-specified equivalence criterion for the primary PK and PD parameters was 90% confidence interval (CI) for geometric means (GM) ratio within 0.80 to 1.25.

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PMC9341513

Figure 4D shows simulated 4C with viewpoints positioned at gene promoters (top four rows).

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PMC9429973

Aims: Here, we report DeepDecon, a deep neural network model that utilizes NGS RNAseq data to detect MRD of AML.

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PMC11638764

The results reveal distinct compartment-specific protein regulation, providing insight into p97/VCP’s cellular mechanisms and its potential for targeted therapeutic applications.(A) Titration curves of CB-5083 in HCT116 and HL-60 cell lines.

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PMC11471157

Asterisks indicate DFP. (

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PMC9429973

The persistence of leukemic stem cells (LSCs) is one of the reasons for relapse in AML.

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PMC11650848

By analysing the results in our longitudinal cohort, we also show a clear interaction with nutrition in determining methylation, and by extension transcription, at the ZFP57 locus, with nutrition having a smaller effect (approx.

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PMC11759543

Z-IETD-FMK and Z-VAD-FMK were purchased from TargetMol (MA, USA).

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PMC11089031

indicates P < 0.05; ** indicates P < 0.01; *** indicates P < 0.001; **** indicates P < 0.0001 Since there are limited reports regarding ZNF692 target genes, we determined the genes whose expression correlated with ZNF692 expression and performed gene set enrichment analysis (GSEA) using those correlated genes to explor...

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PMC11297139

Consequently, it is plausible that oncogenic factors equipped with PrLDs and IDR might co-opt the BAF complex by directly interacting with ARID1A.

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PMC11317131

A second plasmid called the accessory plasmid (AP), contained the attP site and the remaining portion of gIII (N1-C domains).

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PMC11283030

There are some weaknesses of this study.

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PMC5311252

For phenotype validation (flow cytometry and clonogenic assay) of miR-372 effects, stable hsa-mir-372-expressing cell lines and control cell lines were generated as follows.

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PMC9268183

Besides the extensive use of some of these drugs in therapies, such as those derived from the genus Taxus, a significant number of plants have revealed themselves as useful against cancer in recent years.

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PMC10092581

For almost all the silver(I) selenourea complexes, the metal content was rather different than that of the chalcogen and, in many cases, the intracellular amount of Se was significantly higher than that of Ag.

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PMC11610461

The connection of PSENEN expression level with WHO grade in KIRC tissues (G1: n = 6, G2: n = 10, G3: n = 5, G4: n = 2). (

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PMC11734514

Wound was created through the monolayer using a sterile 200 μL pipette tip, and cells debris was removed by washing with PBS three times.8,9 Wound was observed under a microscope and measured to calculate the migration rate using the formula, including percentage wound healing for 24 and 48 hours = [(wound length at 0 ...

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PMC9429973

The del5q was isolated in two RA cases as a del (5) (q13 q33) in a new diagnosed and a treated patients.

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PMC11789597

The GSEA was performed on omicstudio.cn.

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PMC11791203

A sample volume of 1µL was injected into the system.

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PMC10719213

Membranes were washed once with 2× SSC/0.1% SDS for 60 minutes, followed by 0.5× SSC/0.1% SDS for 60 minutes and finally in 0.1× SSC/0.1% SDS for 30 minutes.

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PMC9429973

We used our in-house data analysis pipeline for variant calling.

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PMC11683240

The remaining of each fraction was stored at −80 °C.

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PMC11594806

Another strategy involves combining DTX with the A2BR antagonist BAY606583, which inhibits the ERK signaling pathway and has shown antiproliferative effects on esophageal cancer cells .

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PMC8701144

WF images were acquired for 30 Z planes and are displayed as maximum intensity projections rendered from all Z planes.

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PMC11756907

The sample was topped up with an appropriate solvent (EtOH/DMSO) to a volume of 6 mL. The following suspensions were obtained: GO-2-ME in ethanol at a concentration of 0.25 mg/mL (based on the mass of graphene oxide).GO-2-ME in DMSO at a concentration of 0.25 mg/mL (based on the weight of graphene oxide).50 GO-2-ME in ...

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PMC9429973

Aims: This study aims to predict the risk factors that cause PRES in pediatric patients undergoing allo-HSCT and to evaluate the management of PRES.

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PMC11615828

Live‐cell imaging showed that Spike efficiently bound to the cell surface and then gradually moved to the interior of cells in ACE2‐positive HeLa cells (DMSO treated groups in Figure 7b,c, green curve; Video S29, upper panel, Supporting Information).

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PMC11604830

The higher sensitivity of the CSI approach was tested with a linear coil to directly compare the two techniques.

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PMC11754784

Both type I and type II leakage of DNP3 in complex cell mixtures can be simulated computationally.

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PMC11012313

However, both historical and more recent data indicate that while there are some similarities between LMP2A and BCR signaling, downstream LMP2A signaling is unique in regards to the molecules that are constitutively activated in resting and transformed cells .

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PMC9429973

Sequencing 261 genes (N=42) identified mutations in JAK2 (45%), CALR (43%), and MPL (5%).

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PMC9429973

In addition, both RNAseq and WES identified additional genetic abnormalities not found by conventional approaches.

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PMC11453295

Importantly, analysis of mammary glands two-month post-MIND injections showed engraftment of human cells positive for cytokeratin-5 and lamin a/c.

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PMC8427838

TMIGD1 expressing cells were selected with puromycin.

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PMC11782780

Previous studies have shown that the silencing of EBF3 promotes the progression of malignant tumors, but its impact on the stem-like phenotype of tumor cells remains unexplored.

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PMC10671321

In the motor system, it is essentially produced and secreted by muscle cells and preferentially accumulated in the extracellular matrix of the neuromuscular junction (NMJ).

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PMC11297139

d The rank of transcription factor motifs overrepresented in the ARID1A LLPS-dependent upregulated cREs.

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PMC9429973

The meta-analysis suggests that variants below a certain threshold, here empirically 10%, may in many cases be false-positive variants, in agreement with other reports involving WES in general, introduced by erroneous base calling, PCR errors, etc.

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PMC9910796

To evaluate the hypothesis that pEP84R itself may guide the localization of the core shell precursors we performed immunofluorescence (Fig 5) and immuno-EM (Fig 6) approaches on transfected cells expressing proteins pEP84R-Flag, pp220 and pp62 individually or in combination.

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