OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11622247	Underlines mark 2′-OMe modifications.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Underlines", "mark", "2′-OMe", "modifications", "." ] } ]
PMC11055323	For the 3D Structure Reconstruction, Hi-C reads were remapped by BWA-MEM (Version 0.7.17) to the reference human genome (hg38) with default parameters.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9368503	Assessment of the growth rate of ICR-SS-1 showed exponential growth with a population doubling time of 93 h (Figure 3C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Assessmen...
PMC10969097	The search was adapted to each database, using the following terms: (Mushrooms OR mushroom extracts OR medicinal mushrooms) AND (synergy OR combined effect OR synergistic interaction OR potentiation OR interaction) AND (chemotherapy OR chemotherapeutic agents OR cancer treatment) AND (chemoresistance OR treatment resis...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10170482	P < 0.001 denotes significant differences with respect to the monolayer culture. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P", "<", "0.001", "denotes", "significant", "differences", "with", "respect...
PMC11240052	a,b).	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "a", ",", "b", ")", "." ] } ]
PMC11224020	merging results from upregulated and downregulated genes only as well as all regulated genes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "merging", "results", "from", "upregulated", "and", "downregulated", "g...
PMC9592219	The U6 served as the control for standardizing miRNA, and ATCB was used as the control to standardize mRNA (Table S1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	The HIV pandemic of 1980s represents a similar period with data and insights acquired over years.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "HIV", "pandemic", "of", "1980s", "represents", ...
PMC11482552	One of the major drawbacks of the use of molecular HPV assays is the lack of standardized criteria regarding the minimum cellularity required to define sample adequacy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9812014	Further investigation revealed that these alkaloids decreased viral RNA copies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Further", "investigation", "revealed", "that", "these", "alkaloids", "decreased", "viral", "RNA", ...
PMC11703896	Vina was used to determine the docking affinity of ligands with receptors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Vina", "was", "used", "to", "determine", "the", "docking", "affinity", "of", ...
PMC9841531	To oppose the limited data situation and reduce data variation, the development of novel, easier-to-apply, reliable, and robust assays is an important factor, also in terms of the exploration of novel pharmacological drug targets.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11482552	Similarly, the use of the CCR5 gene target has also been previously described for the normalization of HIV-1 pro-viral loads in clinical samples .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11267036	The mechanisms through which DHM suppressed MM progression were displayed in Fig. 5.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mechanisms", "through", "which", "DHM", "suppressed", "MM", "progres...
PMC11786156	Scale bar: 50.0 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", ":", "50.0", "μm", "." ] } ]
PMC10988555	A control of pDNA cleaved with Hind III endonuclease was also used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "control", "of", "pDNA", "cleaved", "with", "Hind", "III", "endonuclease", ...
PMC9693627	A maximum mass deviation of 4.5 ppm was allowed for precursor’s identification and 20 ppm were set as match tolerance for fragment identification (acquisition in Orbitrap).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11742431	The 0 h as a control. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "0", "h", "as", "a", "control", ".", "(" ] } ]
PMC7642379	Interestingly, the fumarate hydratase gene along with the neighboring kynurenine 3-monooxygenase (KMO) gene, had a log2-fold copy ratio of < -1 in 293E, 293-F and Freestyle 293-F cell lines compared to the parental HEK293 (Fig. 2b and Supplementary Fig. S4), suggesting that these cells have half the number of copies co...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellL...
PMC9429973	Better responses were seen with mRNA-based vaccines and in transplanted patients, indicating that mRNA vaccines and stem cell transplantation may provide higher stimuli to the immune system and provide higher disease control and better immune reconstitution, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11697703	To test whether this finding extends to endogenous Mapk8 mRNA and protein expression in mouse cortical neurons, we first performed loss-of-function (LoF) experiments in neuron cultures enriched in corticospinal and other corticofugal projection neuron subtypes (Figures 2D–2F).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11706297	Afterwards, 4,5-dihydropyrazole-carbothioamides (B1 and B2) were synthesized via the reaction of A1 and A2 with thiosemicarbazide.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Afterwards", ",", "4,5-dihydropyrazole-...
PMC11474209	Physical and biological methods, including applying chemicals, algaecides, and phosphorus precipitation, have been utilized to diminish the severity of cyanobacterial blooms .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC6600253	Primary murine lymphomas have been shown to respond to chemotherapeutic treatment with cyclophosphamide by engaging a senescence program controlled by p53 and p16 .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Primary...
PMC11422497	Kim et al. reported that RAS-stimulated release of exosomes miR-494-3p promotes the osteolytic bone metastasis of breast cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Kim", "et", "al."...
PMC11271278	These include both “trans” hijacking events that relocate enhancers from other chromosomes to a HAPI gene and “cis” hijacking events that relocate distant enhancers (>2 Mb, the upper limit of typical TAD domains) on the same chromosome.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The most common all-grade adverse events (AEs) were headache (pts: 18% [<3 mo], 22% [3 to <6 mo], 12.5% [6 to ≤12 mo], 10% [>12 mo]) and thrombocytopenia (pts: 21% [<3 mo], 17% [3 to <6 mo], 12.5% [6 to ≤12 mo], 0% [>12 mo]).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11413393	Dropout values represent the fold decrease in GFP+ cells at each passage, relative to the GFP+ percentage on day 0.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Dropout", "values", ...
PMC6948907	There was a significant difference between the percentages of the cell viability of single agent treatment and combination treatment groups, between GE (24h) and GE/VPA (24 and 48 h) groups (P < 0.03), between GE 48h and GE/VPA 48 h groups (P < 0.013), between VPA 24h and GE/VPA 24 and 48 h groups (P < 0.002) and betwe...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7022782	Cardiogreen (ICG) and Tween 20 were obtained from Sigma-Aldrich (St. Louis, MO, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cardiogreen", "(", "ICG", ")", ...
PMC11367146	Red indicates highly expressive genes, whereas blue indicates less expressive genes of OA. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Red", "indicates", "highly", "expressive", "genes", ",", "w...
PMC11412721	Here, on the contrary, male mice and a subset of male patients were more efficiently protected against Burkitt-like lymphomas, which adds another layer of complexity to sex-specific differences in tumorigenesis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9473868	The PI3K/Akt/mTOR signaling pathway is an important signaling pathway in the cell proliferation and apoptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "PI3K/Akt/mTOR", "signaling", "pathway", "is", "an", ...
PMC11224020	Hair was removed with forceps.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hair", "was", "removed", "with", "forceps", "." ] } ]
PMC2118063	RNA prepared from splenic B cells from IRF8-deficient and WT mice was tested by qPCR for expression of Bcl6 and Aicda.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RNA", "prepared", ...
PMC11765988	Propionibacterium acnes, a skin commensal bacterium, is the only documented micro-organism cultured from sarcoid tissues.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Propionibacterium", "acnes", ",", "a", "skin", ...
PMC9429973	Study drug will be administered at a range of 1–50 mg twice daily, depending on age and weight; dosing categories are derived from pharmacokinetic modeling data of adults with PK deficiency.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11701801	The cells were then reseeded again and treated with CP-C27.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cells", "were", "then", "reseeded", "again", "and", "treated", "with", "CP-C27", "....
PMC11507371	In this regard, cold atmospheric pressure plasma (CAP) is proving to be a promising tool for skin cancer therapy .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "this",...
PMC9509578	Etoposide intracellular efficiency was enhanced by lipid nanocapsules in P-gp-overexpressing MDR cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Etoposide", "intracellular", "efficiency", "was", "enhanced", "by", "lipid", "nanocaps...
PMC7602170	Although most patients with advanced GISTs display remarkable clinical benefits from TKI therapy by imatinib, resistance to TKIs occurs in half of those GIST patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11401358	Hydrophobicity index of the Bombyx mori SF heavy chain, which is composed of a tyrosine-rich amorphous sequence (purple, blue and green) and 12 highly repetitive amino acid sequences (orange). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11301242	Data were log2 converted. (	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "were", "log2", "converted", ".", "(" ] } ]
PMC11499381	Data analysis was automated, meaning that the analysis pipeline was essentially blinded.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "analysis", "was", "automated", ",", "meaning", "that", "the", ...
PMC8348645	The powdered plant samples were filtered using a sieve to remove larger lumps.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "powdered", "plant", "samples", "were", "filtered", "using", "a", ...
PMC9429973	In addition, the impact of SPM diagnosis on MM management and outcome are reported.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", "the", "impact", "of", "SPM", "...
PMC8658661	Their study showed that in the HepG2 cell line, acetate, creatine, isoleucine, leucine, and phenylalanine were increased, which indicates a more enhanced lipid metabolism and active absorption of nutrients from the media than in L-02 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Summary/Conclusion: In this post hoc analysis of the ACE-LY-004 study of acalabrutinib in adult patients with confirmed R/R MCL, a shorter DOR was observed among patients who received acalabrutinib after 1 prior therapy compared with those who received acalabrutinib after ≥2 prior therapies, likely explained by a high ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2614416	The results are presented in a Sequence Table.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "results", "are", "presented", "in", "a", "Sequence", "Table", "." ] } ]
PMC8526701	A GIST-882 cells were treated with GSK602 at indicated concentrations for 24 h. Left, PUMA expression was analyzed by western blotting.	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", ...
PMC7022782	Fluorescence measurements were performed using an RF-6000 spectrofluorometer (Shimadzu, Kyoto, Japan) with an excitation wavelength of 785 nm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fluorescence", ...
PMC10631132	The CMP in turn gives rise to the megakaryocyte/erythrocyte progenitor (MEP) and granulocyte/macrophage progenitor (GMP).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "CMP", "in", "turn", ...
PMC11694625	The presence of the hydrazone group was confirmed by broad signal of NH protons and CHN protons at 11.79–11.35 ppm, 9.43–8.31 ppm respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11763111	At 48 h, the proportions of 4KO-LLT1 and 1KO CAR-T cells were significantly higher than those of 4KO CAR-T and PCDH-T cells (Fig. 5F).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8481254	STZ-treated mice were also intraperitoneally injected daily with saline or insulin (Sigma, St. Louis, MO), with a final concentration of 2 units/kg.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6892818	ACHN, 786-O and A-704 cells treated with mCD40L for 24 h in the absence of inhibitor (vehicle controls) were also included (denoted as positive control, ‘PC') for each experiment.	[ { "tags": [ "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC11467800	These cells are Bcr‐Abl‐independent, no longer relying on it for survival.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "cells", "are", "Bcr‐Abl‐independent", ",", "no", "longer", "relying", "...
PMC9429973	With first-line therapy, 54% of pts (n=50) achieved MRR vs. 46% (n=42) who did not.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "With", "firs...
PMC9429973	387 reported vaccination with 282 fully vaccinated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "387", "reported", "vaccination", "with", "282", "fully", "vaccinated", "." ] } ]
PMC7338939	This similar pattern of expression may be related to day of sampling, because we removed all tumors at day 15 with increasing tumor growth.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11240052	All the cells were maintained in an incubator with 5% CO2 and saturated humidity at 37 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "the", "cells", "were", ...
PMC9031474	Another potential target of drimanes and coloratanes is the TRPA1 (transient receptor potential ankyrin 1) ion channel.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Another", "potential", "target", ...
PMC11629192	Unlike in anti-NMDAR encephalitis, B-cell depletion in MS is not typically used for acute relapse management, which is generally administered with high-dose corticosteroids.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11033180	Among the most prevalent comorbidities in ASD are gastrointestinal (GI) symptoms which are 4.4 times more frequent than in neurotypical individuals.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Among",...
PMC9895440	Further information on research design is available in the Nature Portfolio Reporting Summary linked to this article.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Further", "information", "on", "research", "desig...
PMC11727306	Statistical analysis of data was performed using SigmaStat 3.5 for Windows (Systat Software, San Jose, CA, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", ...
PMC9681981	Enterotoxemia is endemic in Iran, and millions of vaccine doses are annually produced by the RVSRI in Iran.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Enterotoxemia", "is", "endemic", ...
PMC11548041	The data were analyzed using the LightCycler software (96 SW 1.0, Roche Diagnostics, Mannheim, Germany), and β-catenin expression was normalized to that of the housekeeping gene.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: We aimed to determine the efficacy and safety profile of the association ixazomib, pomalidomide and dexamethasone HR RRMM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "We",...
PMC11546117	In addition, serum-free medium or medium without cholera toxin was explored.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", "serum-free", "medium", "or", "medium", "without", "choler...
PMC9429973	The IBS for the stacking, IPS, and IPS-3 model was 0.078, 0.099, and 0.096, respectively, while the C-Index was 0.86, 0.73, and 0.71.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10758402	We detected an increase in the CD3+ population inside the tumor compartment of mice treated with the combination regimen compared to all other groups by day 14; however, this did not reach statistical significance comparing to individual groups in post-hoc tests (ANOVA p=0.09, Figure 6A ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11532793	The faster computing time of edgeR-v4 over edgeR-v3 was a result of the newer estimation strategy of quasi-dispersions from edgeR, which allows the estimation of transcript-wise NB-dispersions to be completely bypassed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11549062	We also tested the carotid VSMCs migration and proliferation using Edu staining and scratch wound test.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "also", "tested", "the", "carotid", "VSMCs", ...
PMC9910796	ASFV-infected Vero cells or transfected Cos cells, seeded on glass coverslips, were infected with parental ASFV virus or recombinant vEP84Ri for the indicated times, washed with PBS and fixed with methanol at -20°C for 5 min or with 4% PFA in PBS for 15 min at RT.	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC4360730	In the current phase starting in 2012, the ENCODE project has added new genomic assays, a greater diversity of biological samples used in investigations, additional species (D. melanogaster and C. elegans) and new methods for validating and analyzing experimental data.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10728535	These genes include PITX2, FIBIN, LRRTM4, ANO3, SNCA, FOLH1, KANK4, FGF18, POSTN, KANK1, GALNT14, EPHA7, ECEL1, and EPHX2 (Figures 5 and 6).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9352806	The influences of BMS on the lifespan in daf-16 deficient mutant (D) (Control, n = 160; BMS 100, n = 144), hlh-30 deficient worms (E) (Control, n = 160; BMS 100, n = 129), and hlh-30 interfered worms (F) (Control, n = 110; BMS 100, n = 109).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11257203	Furthermore, the average ratio of PCE to NCE in the group treated simultaneously with indomethacin (20 and 40 mg/kg) and curcumin (100 mg/kg) showed a significant increase compared to the group treated only with the same dose of indomethacin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11711663	Smoking and alcohol status were self-reported.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Smoking", "and", "alcohol", "status", "were", "self-reported", "." ] } ]
PMC9429973	Medical charts of all patients in both groups were retrieved from the hospital’s main archive and reviewed for the presence of venous and/or arterial thrombosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10812665	Altogether, such relatively unspecific transcriptome regulations resulted here in a statistical over-representation of genes associated with systemic lupus erythematosus and alcoholism.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Altogether", ...
PMC11286266	Re-probing the blot with an anti-GFP antibody revealed that GFP-ATF6_LD was expressed at lower levels than ATF6α_LD (Figure 4C), potentially accounting for the reduced recovery of CRT in complex with ATF6α_LD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4695073	siRNAs sequences (Supplemental Table S2) referred to previously reports .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "siRNAs", "sequences", "(", "Supplemental", "Table", "S2", ")", "referred", "to", "pre...
PMC11589157	To identify repeat sequences in the gibbon genome, a combination of de novo and homology-based approaches was employed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "identify", "repeat", "seque...
PMC9429973	Here, we present preliminary data from the phase 2 trial of Zanubrutinib combined with immunochemotherapy in pts with CD79A/CD79B-mutant DLBCL (NCT04668365).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11786767	We further investigated the distribution of lipid components at the perichromosomal layers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "further", "investigated", "the", "distribution", "of", "lipid", "components", ...
PMC9429973	A. Bazinet, E. Jabbour, H. Kantarjian, K. Chien, C. DiNardo, M. Ohanian, N. Daver, R. Kanagal-Shamanna, T. Kadia, K. Takahashi, L. Masarova, N. Short, Y. Alvarado, P. Thompson, G. Montalban-Bravo, M. Yilmaz, F. Ravandi, M. Konopleva, M. Andreeff, S. Kornblau, N. Pemmaraju, D. Hammond, H. Schneider, B. Mirabella, G. Gar...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11463018	H NMR (400 MHz, Chloroform-d) δ: 12.03 (s, 1H), 8.81 (d, J = 7.8 Hz, 1H), 8.15 (s, 1H), 7.60 (t, J = 8.0 Hz, 1H), 7.32 (dd, J = 7.7, 0.6 Hz, 1H), 4.32–4.30 (m, 2H), 1.35 (t, J = 7.1 Hz, 3H).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11781181	HRP-conjugated goat secondary antibodies were used (diluted 1:5,000, Invitrogen).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HRP-conjugated", "goat", "secondary", "antibodies", "were", "used", "(", "diluted", ...
PMC11727062	Bufonidae, characterized as cool in nature, pungent, and toxic, is associated with the Heart, Liver, Spleen, and Lung meridians in TCM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	To study the impact of hnRNP K overexpression in vivo, we developed an inducible tamoxifen mouse model activated 30-60 days after birth (Hnrnpk).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11323699	Second, resistance to PARP inhibitors (PARPis) is one of the most important and immediate challenges facing oncologists today (Fig. 1, bottom panel).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Being these samples left outside the digital world, it is not possible to leverage tools such as Artificial Intelligence (AI) algorithms to support diagnosis in hematological medical images.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7351993	The mutant library was cultured under phototrophic conditions (continuous illumination at 250 μmol photons m s with 2% CO2 aeration at 30 °C) using double-deck photobioreactors (lower stage containing 2 M NaHCO3/Na2CO3 to supply CO2 gas and upper stage containing cell culture) and Modified Bold (MB) 6 N medium for 4 da...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9917080	Cortical tissue cuts from one animal were used for each cell culture preparation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cortical", "tissue", "cuts", "from", "one", "animal", "were", "used", ...
PMC11291490	This enhancement could be attributed to the role of the CD40-CD40L signaling pathway in promoting B cell proliferation, differentiation, activation, and antibody production.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC7081114	In vitro reconstitution studies show that KIF21B increases the microtubule growth rate and catastrophe frequency.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "vitro", "reconstitution", "studies", "show", "that", ...
PMC11342785	Upon rapamycin treatment, a synMAP’s MT binding and IDR components become connected to stimulate the assembly of higher-order MT structures.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Upon", "rapa...

PMC11622247

Underlines mark 2′-OMe modifications.

[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Underlines", "mark", "2′-OMe", "modifications", "." ] } ]

PMC11055323

For the 3D Structure Reconstruction, Hi-C reads were remapped by BWA-MEM (Version 0.7.17) to the reference human genome (hg38) with default parameters.

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PMC9368503

Assessment of the growth rate of ICR-SS-1 showed exponential growth with a population doubling time of 93 h (Figure 3C).

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PMC10969097

The search was adapted to each database, using the following terms: (Mushrooms OR mushroom extracts OR medicinal mushrooms) AND (synergy OR combined effect OR synergistic interaction OR potentiation OR interaction) AND (chemotherapy OR chemotherapeutic agents OR cancer treatment) AND (chemoresistance OR treatment resis...

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PMC10170482

P < 0.001 denotes significant differences with respect to the monolayer culture. (

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PMC11240052

a,b).

[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "a", ",", "b", ")", "." ] } ]

PMC11224020

merging results from upregulated and downregulated genes only as well as all regulated genes.

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PMC9592219

The U6 served as the control for standardizing miRNA, and ATCB was used as the control to standardize mRNA (Table S1).

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PMC9429973

The HIV pandemic of 1980s represents a similar period with data and insights acquired over years.

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PMC11482552

One of the major drawbacks of the use of molecular HPV assays is the lack of standardized criteria regarding the minimum cellularity required to define sample adequacy.

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PMC9812014

Further investigation revealed that these alkaloids decreased viral RNA copies.

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PMC11703896

Vina was used to determine the docking affinity of ligands with receptors.

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PMC9841531

To oppose the limited data situation and reduce data variation, the development of novel, easier-to-apply, reliable, and robust assays is an important factor, also in terms of the exploration of novel pharmacological drug targets.

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PMC11482552

Similarly, the use of the CCR5 gene target has also been previously described for the normalization of HIV-1 pro-viral loads in clinical samples .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11267036

The mechanisms through which DHM suppressed MM progression were displayed in Fig. 5.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mechanisms", "through", "which", "DHM", "suppressed", "MM", "progres...

PMC11786156

Scale bar: 50.0 μm.

[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", ":", "50.0", "μm", "." ] } ]

PMC10988555

A control of pDNA cleaved with Hind III endonuclease was also used.

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PMC9693627

A maximum mass deviation of 4.5 ppm was allowed for precursor’s identification and 20 ppm were set as match tolerance for fragment identification (acquisition in Orbitrap).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11742431

The 0 h as a control. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "0", "h", "as", "a", "control", ".", "(" ] } ]

PMC7642379

Interestingly, the fumarate hydratase gene along with the neighboring kynurenine 3-monooxygenase (KMO) gene, had a log2-fold copy ratio of < -1 in 293E, 293-F and Freestyle 293-F cell lines compared to the parental HEK293 (Fig. 2b and Supplementary Fig. S4), suggesting that these cells have half the number of copies co...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellL...

PMC9429973

Better responses were seen with mRNA-based vaccines and in transplanted patients, indicating that mRNA vaccines and stem cell transplantation may provide higher stimuli to the immune system and provide higher disease control and better immune reconstitution, respectively.

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PMC11697703

To test whether this finding extends to endogenous Mapk8 mRNA and protein expression in mouse cortical neurons, we first performed loss-of-function (LoF) experiments in neuron cultures enriched in corticospinal and other corticofugal projection neuron subtypes (Figures 2D–2F).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11706297

Afterwards, 4,5-dihydropyrazole-carbothioamides (B1 and B2) were synthesized via the reaction of A1 and A2 with thiosemicarbazide.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Afterwards", ",", "4,5-dihydropyrazole-...

PMC11474209

Physical and biological methods, including applying chemicals, algaecides, and phosphorus precipitation, have been utilized to diminish the severity of cyanobacterial blooms .

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PMC6600253

Primary murine lymphomas have been shown to respond to chemotherapeutic treatment with cyclophosphamide by engaging a senescence program controlled by p53 and p16 .

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PMC11422497

Kim et al. reported that RAS-stimulated release of exosomes miR-494-3p promotes the osteolytic bone metastasis of breast cancer cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Kim", "et", "al."...

PMC11271278

These include both “trans” hijacking events that relocate enhancers from other chromosomes to a HAPI gene and “cis” hijacking events that relocate distant enhancers (>2 Mb, the upper limit of typical TAD domains) on the same chromosome.

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PMC9429973

The most common all-grade adverse events (AEs) were headache (pts: 18% [<3 mo], 22% [3 to <6 mo], 12.5% [6 to ≤12 mo], 10% [>12 mo]) and thrombocytopenia (pts: 21% [<3 mo], 17% [3 to <6 mo], 12.5% [6 to ≤12 mo], 0% [>12 mo]).

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PMC11413393

Dropout values represent the fold decrease in GFP+ cells at each passage, relative to the GFP+ percentage on day 0.

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PMC6948907

There was a significant difference between the percentages of the cell viability of single agent treatment and combination treatment groups, between GE (24h) and GE/VPA (24 and 48 h) groups (P < 0.03), between GE 48h and GE/VPA 48 h groups (P < 0.013), between VPA 24h and GE/VPA 24 and 48 h groups (P < 0.002) and betwe...

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PMC7022782

Cardiogreen (ICG) and Tween 20 were obtained from Sigma-Aldrich (St. Louis, MO, USA).

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PMC11367146

Red indicates highly expressive genes, whereas blue indicates less expressive genes of OA. (

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PMC11412721

Here, on the contrary, male mice and a subset of male patients were more efficiently protected against Burkitt-like lymphomas, which adds another layer of complexity to sex-specific differences in tumorigenesis.

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PMC9473868

The PI3K/Akt/mTOR signaling pathway is an important signaling pathway in the cell proliferation and apoptosis.

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PMC11224020

Hair was removed with forceps.

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PMC2118063

RNA prepared from splenic B cells from IRF8-deficient and WT mice was tested by qPCR for expression of Bcl6 and Aicda.

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PMC11765988

Propionibacterium acnes, a skin commensal bacterium, is the only documented micro-organism cultured from sarcoid tissues.

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PMC9429973

Study drug will be administered at a range of 1–50 mg twice daily, depending on age and weight; dosing categories are derived from pharmacokinetic modeling data of adults with PK deficiency.

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PMC11701801

The cells were then reseeded again and treated with CP-C27.

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PMC11507371

In this regard, cold atmospheric pressure plasma (CAP) is proving to be a promising tool for skin cancer therapy .

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PMC9509578

Etoposide intracellular efficiency was enhanced by lipid nanocapsules in P-gp-overexpressing MDR cells .

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PMC7602170

Although most patients with advanced GISTs display remarkable clinical benefits from TKI therapy by imatinib, resistance to TKIs occurs in half of those GIST patients.

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PMC11401358

Hydrophobicity index of the Bombyx mori SF heavy chain, which is composed of a tyrosine-rich amorphous sequence (purple, blue and green) and 12 highly repetitive amino acid sequences (orange). (

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PMC11301242

Data were log2 converted. (

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PMC11499381

Data analysis was automated, meaning that the analysis pipeline was essentially blinded.

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PMC8348645

The powdered plant samples were filtered using a sieve to remove larger lumps.

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PMC9429973

In addition, the impact of SPM diagnosis on MM management and outcome are reported.

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PMC8658661

Their study showed that in the HepG2 cell line, acetate, creatine, isoleucine, leucine, and phenylalanine were increased, which indicates a more enhanced lipid metabolism and active absorption of nutrients from the media than in L-02 cells.

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PMC9429973

Summary/Conclusion: In this post hoc analysis of the ACE-LY-004 study of acalabrutinib in adult patients with confirmed R/R MCL, a shorter DOR was observed among patients who received acalabrutinib after 1 prior therapy compared with those who received acalabrutinib after ≥2 prior therapies, likely explained by a high ...

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PMC2614416

The results are presented in a Sequence Table.

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PMC8526701

A GIST-882 cells were treated with GSK602 at indicated concentrations for 24 h. Left, PUMA expression was analyzed by western blotting.

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PMC7022782

Fluorescence measurements were performed using an RF-6000 spectrofluorometer (Shimadzu, Kyoto, Japan) with an excitation wavelength of 785 nm.

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PMC10631132

The CMP in turn gives rise to the megakaryocyte/erythrocyte progenitor (MEP) and granulocyte/macrophage progenitor (GMP).

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PMC11694625

The presence of the hydrazone group was confirmed by broad signal of NH protons and CHN protons at 11.79–11.35 ppm, 9.43–8.31 ppm respectively.

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PMC11763111

At 48 h, the proportions of 4KO-LLT1 and 1KO CAR-T cells were significantly higher than those of 4KO CAR-T and PCDH-T cells (Fig. 5F).

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PMC8481254

STZ-treated mice were also intraperitoneally injected daily with saline or insulin (Sigma, St. Louis, MO), with a final concentration of 2 units/kg.

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PMC6892818

ACHN, 786-O and A-704 cells treated with mCD40L for 24 h in the absence of inhibitor (vehicle controls) were also included (denoted as positive control, ‘PC') for each experiment.

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PMC11467800

These cells are Bcr‐Abl‐independent, no longer relying on it for survival.

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PMC9429973

With first-line therapy, 54% of pts (n=50) achieved MRR vs. 46% (n=42) who did not.

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PMC9429973

387 reported vaccination with 282 fully vaccinated.

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PMC7338939

This similar pattern of expression may be related to day of sampling, because we removed all tumors at day 15 with increasing tumor growth.

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PMC11240052

All the cells were maintained in an incubator with 5% CO2 and saturated humidity at 37 °C.

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PMC9031474

Another potential target of drimanes and coloratanes is the TRPA1 (transient receptor potential ankyrin 1) ion channel.

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PMC11629192

Unlike in anti-NMDAR encephalitis, B-cell depletion in MS is not typically used for acute relapse management, which is generally administered with high-dose corticosteroids.

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PMC11033180

Among the most prevalent comorbidities in ASD are gastrointestinal (GI) symptoms which are 4.4 times more frequent than in neurotypical individuals.

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PMC9895440

Further information on research design is available in the Nature Portfolio Reporting Summary linked to this article.

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PMC11727306

Statistical analysis of data was performed using SigmaStat 3.5 for Windows (Systat Software, San Jose, CA, USA).

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PMC9681981

Enterotoxemia is endemic in Iran, and millions of vaccine doses are annually produced by the RVSRI in Iran.

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PMC11548041

The data were analyzed using the LightCycler software (96 SW 1.0, Roche Diagnostics, Mannheim, Germany), and β-catenin expression was normalized to that of the housekeeping gene.

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PMC9429973

Aims: We aimed to determine the efficacy and safety profile of the association ixazomib, pomalidomide and dexamethasone HR RRMM.

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PMC11546117

In addition, serum-free medium or medium without cholera toxin was explored.

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PMC9429973

The IBS for the stacking, IPS, and IPS-3 model was 0.078, 0.099, and 0.096, respectively, while the C-Index was 0.86, 0.73, and 0.71.

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PMC10758402

We detected an increase in the CD3+ population inside the tumor compartment of mice treated with the combination regimen compared to all other groups by day 14; however, this did not reach statistical significance comparing to individual groups in post-hoc tests (ANOVA p=0.09, Figure 6A ).

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PMC11532793

The faster computing time of edgeR-v4 over edgeR-v3 was a result of the newer estimation strategy of quasi-dispersions from edgeR, which allows the estimation of transcript-wise NB-dispersions to be completely bypassed.

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PMC11549062

We also tested the carotid VSMCs migration and proliferation using Edu staining and scratch wound test.

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PMC9910796

ASFV-infected Vero cells or transfected Cos cells, seeded on glass coverslips, were infected with parental ASFV virus or recombinant vEP84Ri for the indicated times, washed with PBS and fixed with methanol at -20°C for 5 min or with 4% PFA in PBS for 15 min at RT.

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PMC4360730

In the current phase starting in 2012, the ENCODE project has added new genomic assays, a greater diversity of biological samples used in investigations, additional species (D. melanogaster and C. elegans) and new methods for validating and analyzing experimental data.

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PMC10728535

These genes include PITX2, FIBIN, LRRTM4, ANO3, SNCA, FOLH1, KANK4, FGF18, POSTN, KANK1, GALNT14, EPHA7, ECEL1, and EPHX2 (Figures 5 and 6).

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PMC9352806

The influences of BMS on the lifespan in daf-16 deficient mutant (D) (Control, n = 160; BMS 100, n = 144), hlh-30 deficient worms (E) (Control, n = 160; BMS 100, n = 129), and hlh-30 interfered worms (F) (Control, n = 110; BMS 100, n = 109).

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PMC11257203

Furthermore, the average ratio of PCE to NCE in the group treated simultaneously with indomethacin (20 and 40 mg/kg) and curcumin (100 mg/kg) showed a significant increase compared to the group treated only with the same dose of indomethacin.

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PMC11711663

Smoking and alcohol status were self-reported.

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PMC9429973

Medical charts of all patients in both groups were retrieved from the hospital’s main archive and reviewed for the presence of venous and/or arterial thrombosis.

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PMC10812665

Altogether, such relatively unspecific transcriptome regulations resulted here in a statistical over-representation of genes associated with systemic lupus erythematosus and alcoholism.

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PMC11286266

Re-probing the blot with an anti-GFP antibody revealed that GFP-ATF6_LD was expressed at lower levels than ATF6α_LD (Figure 4C), potentially accounting for the reduced recovery of CRT in complex with ATF6α_LD.

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PMC4695073

siRNAs sequences (Supplemental Table S2) referred to previously reports .

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PMC11589157

To identify repeat sequences in the gibbon genome, a combination of de novo and homology-based approaches was employed.

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PMC9429973

Here, we present preliminary data from the phase 2 trial of Zanubrutinib combined with immunochemotherapy in pts with CD79A/CD79B-mutant DLBCL (NCT04668365).

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PMC11786767

We further investigated the distribution of lipid components at the perichromosomal layers.

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PMC9429973

A. Bazinet, E. Jabbour, H. Kantarjian, K. Chien, C. DiNardo, M. Ohanian, N. Daver, R. Kanagal-Shamanna, T. Kadia, K. Takahashi, L. Masarova, N. Short, Y. Alvarado, P. Thompson, G. Montalban-Bravo, M. Yilmaz, F. Ravandi, M. Konopleva, M. Andreeff, S. Kornblau, N. Pemmaraju, D. Hammond, H. Schneider, B. Mirabella, G. Gar...

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PMC11463018

H NMR (400 MHz, Chloroform-d) δ: 12.03 (s, 1H), 8.81 (d, J = 7.8 Hz, 1H), 8.15 (s, 1H), 7.60 (t, J = 8.0 Hz, 1H), 7.32 (dd, J = 7.7, 0.6 Hz, 1H), 4.32–4.30 (m, 2H), 1.35 (t, J = 7.1 Hz, 3H).

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PMC11781181

HRP-conjugated goat secondary antibodies were used (diluted 1:5,000, Invitrogen).

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PMC11727062

Bufonidae, characterized as cool in nature, pungent, and toxic, is associated with the Heart, Liver, Spleen, and Lung meridians in TCM.

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PMC9429973

To study the impact of hnRNP K overexpression in vivo, we developed an inducible tamoxifen mouse model activated 30-60 days after birth (Hnrnpk).

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PMC11323699

Second, resistance to PARP inhibitors (PARPis) is one of the most important and immediate challenges facing oncologists today (Fig. 1, bottom panel).

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PMC9429973

Being these samples left outside the digital world, it is not possible to leverage tools such as Artificial Intelligence (AI) algorithms to support diagnosis in hematological medical images.

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PMC7351993

The mutant library was cultured under phototrophic conditions (continuous illumination at 250 μmol photons m s with 2% CO2 aeration at 30 °C) using double-deck photobioreactors (lower stage containing 2 M NaHCO3/Na2CO3 to supply CO2 gas and upper stage containing cell culture) and Modified Bold (MB) 6 N medium for 4 da...

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PMC9917080

Cortical tissue cuts from one animal were used for each cell culture preparation.

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PMC11291490

This enhancement could be attributed to the role of the CD40-CD40L signaling pathway in promoting B cell proliferation, differentiation, activation, and antibody production.

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PMC7081114

In vitro reconstitution studies show that KIF21B increases the microtubule growth rate and catastrophe frequency.

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PMC11342785

Upon rapamycin treatment, a synMAP’s MT binding and IDR components become connected to stimulate the assembly of higher-order MT structures.

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