OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11705067	A venn diagram of differentially expressed genes was created using the online tool Venny2.1.0, and the heatmap and volcano plot of differential expression genes about the gene expression profiles in the GSE53757 and GSE66272 databases were drawn by R software (version 4.0.3; R Foundation).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11206502	Meanwhile, cisplatin-based adjuvant chemotherapy remains a valid option for muscle-invasive bladder cancer .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Meanwhile", ",", "cisplatin-based", "adjuvant", "chemotherapy", "remains", "a", ...
PMC11748335	BEDtools was used for excluding regions within the blacklist .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "BEDtools", "was", "used", "for", "excluding", "regions", "within", "the", "blacklist", "." ] } ]
PMC11653533	Also, β-sitosterol, β-amyrin, and lupiol acetate were isolated from the stem bark of F. glomerata have manifested hypoglycemic potency by activating glucose-6-phosphate dehydrogenase enzyme with an enzyme activity of 273.20, 212.00 and 239.00 unit/min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11670407	a-d To maintain cell number consistency, we transfected 143B or U2OS cells with the indicated siRNAs and overexpression plasmids for 48 h, followed by treatment with MG132 (10 μM) for 6 h before harvesting the cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC7192625	XRCC6BP1 (ATP23) is a gene involved in DNA break repair, often amplified in glioblastoma.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "XRCC6BP1", "(", "ATP23", ")", "is", "a", ...
PMC11528603	Interestingly, Le-Trung et al. recently isolated acetylmelodorinol (AM) from the ethyl acetate fraction of S. affinis seeds.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interestingly", ",", "Le-Tru...
PMC6742971	Therefore, we compared the T cell's function in experiments using T cell clones with defined avidity, by using them individually and in parallel to mixtures of T cell cones with different avidities.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Despite there were no significant differences between the groups of patients with MDS, platelets from patients without AD showed a clear decrease in their ability to be activated by TRAP and was almost absent in three of them.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11723947	To characterize the gene networks that HP1α regulates, we next used deep total RNA-sequencing (RNA-seq) to analyze the transcriptomes of wild-type and mutant cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11583010	T47D (ATCC) and HCT-116 (Horizon Discovery, Perkin Elmer) were cultured in RPMI medium supplemented with 10% FBS.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens"...
PMC7215722	These membranes are liquid-ordered lipid–protein assemblies enriched in cholesterol and sphingolipids that float within the liquid-disordered bilayer of cellular membranes .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "mem...
PMC11144200	K, L Representative fluorescence microscopy images of Hep3B or A-427 cells after incubation with LPS-RGD-Nb36-DOX for 2 h, 4 h, and 6 h, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11204465	This paper reviews the structures, biological activities, biosynthetic pathways, and chemical total synthesis of AFs and STCs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "paper", "reviews", ...
PMC11791264	Error bars represent the mean ± SD (n = 3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Error", "bars", "represent", "the", "mean", "±", "SD", "(", "n", "=", ...
PMC11258145	The integrity of the HL-60 and SK-N-SH membranes after exposure to different concentrations of curcumin was determined by measuring the amount of released lactate dehydrogenase (LDH).	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11621493	I–K) Total MAG, DAG, and TAG levels calculated based on the sum of signals from all detected subspecies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "I", ...
PMC11701801	The ON-TARGETplus SMARTPool siRNAs specific for target genes CREBBP (L-003477-00), EP300 (L-003486-00), KREMEN2 (L-003847-00), and KREMEN1 (L-003846-00) were purchased from Dharmacon.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11482552	In the majority of assays which include an IC, this is associated with the qualitative detection of a Beta-globin gene target, used to assess both the presence of human cells in the sample as well as any potential PCR inhibition in the same reaction well used for the detection of HPV DNA targets.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11472639	Additionally, ADCCPlasma post-exercise (34.1%) was significantly greater than ADCCHI-FCS post-exercise (23.3%) (t(7) = 3.72, p = 0.007, d = 1.31), with a trend towards a difference pre-exercise (t(7) = 2.10, p = 0.07, d = 0.75).Fig.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11787355	Top two gRNAs without self-complementarity were selected and cloned into the lentiCRISPRv2blast construct (Addgene #83480; RRID:Addgene 83480).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Top", ...
PMC11543885	Wash with 2 mL quencher buffer per well for another two times, each wash lasting 1 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Wash", "with", "2", "mL", "quencher", ...
PMC3019555	qRT-PCR was performed using iQ SYBR green supermix (Bio-Rad Laboratories) and the following specific primers: HIF-1α (forward, 5′-TGGTGACATGATTTACATTTCTGA-3′; reverse, 5′-AAGGCCATTTCTGTGTGTAAGC-3′), GAPDH (forward, 5′-GGAGTCAACGGATTTGGTCG-3′; reverse, 5′-CTTGATTTTGGAGGGATCTCG-3′), or p53 (forward, 5′-TCACAGCACATGACGGAG...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	6% vs. 17%, p=0.3, Fig. 1D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "6", "%", "vs.", "17", "%", ",", "p=0.3", ",", "Fig.", "1D", ")", "." ...
PMC11770130	LD-independent SNPs from corresponding GWAS that passed the same SNP filtering and proxy search steps mentioned previously were used as instrument variables.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "LD-independent", ...
PMC9080589	Differences between multiple groups were analyzed by ANOVA followed by Tukey's post hoc test.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Differences", "between", "multiple", "groups", "were", "analyzed"...
PMC9429973	The primary endpoint was mean change from baseline in QTc.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "primary", "endpoint", "was", "mean", "change", "from", "baseline", "in", "QTc", "."...
PMC10577955	After ALUP, BA, and LUP treatment, cells were aggregated at the G2/M phase, thus we tried to measure the number of cells in each stage of apoptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	We have established a workflow to initiate germline genetic testing in pts under suspicion for a HHD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "have", "established", "a", "workflow", ...
PMC11544122	Similar to CXCR4, most GPCRs are robustly phosphorylated on their CTs, including the prototypical GPCRs, which use the β-arrestin mode for endocytosis, such as β2AR, AT1AR, and V2R (Fig. 4c).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11707832	Post-translational modifications of MAN2B1 polypeptides occur within the endoplasmic reticulum.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Post-translational", "modifications", "of", "MAN2B1", "polypeptides", "occur", "within", "the", "endop...
PMC11711935	Wnt inhibitory factor‐1 (WIF‐1) can also promote melanin synthesis in melanocytes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Wnt", "inhibitory", "factor‐1", "(", "WIF‐1", ")", "can", "also", "pr...
PMC10899471	qPCR analysis of MET expression in HT-1080 cells transfected with control or miR-939 mimic or inhibitor. *	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "qPCR", "analysis", "of", "MET", "express...
PMC10898159	These findings indicate the potential of PBOX-15 to improve the apoptotic response of IM in GIST cells and provide a more effective treatment option for GIST patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11763111	According to earlier research, off-the-shelf CAR-T cells do not overproliferate and produce CRS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "According", "to", "earlier", "research", ",", "off-the-shelf", "CAR-T"...
PMC9429973	The percentage of JAK2 positive patients in patients with a score of 1-3 was 24% versus 0.8% in patients with a score of 0.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11806106	After application of a non-saturating concentration of DAMGO, the signal was reversible by application of the antagonist naloxone (Supplementary Fig. 3B) and application of extracellular buffer induced no change in BRET ratio (Supplementary Fig. 3C).Fig.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11413393	n = 5 mice/group (RCC243_NT shRNA (+)Dox, RCC243_PRMT1 shRNA (+)Dox and 786-0_PRMT1 shRNA (+)Dox) and n = 3 mice/group (RCC243_PRMT1 shRNA (-)Dox, 786-0_NT shRNA (+)Dox and 786-0_PRMT1 shRNA (-)Dox).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10329074	For instance, YBX3 promoted the metastasis of nasopharyngeal carcinoma via PI3K/AKT signaling (Fan et al. 2021).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "instance", ",", "YBX3", ...
PMC11750712	The gating strategy is available in the Supplementary Information.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "gating", "strategy", "is", "available", "in", "the", "Supplementary", "Information", "." ] } ]
PMC9429973	In summary, our study uncovers how the TME can contribute to leukemic transformation which provides alternative avenues for therapeutic interventions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "summary", "...
PMC10048572	After growth cells were re-cloned by the limiting dilutions, 180 B4 subclones and 381 O1 subclones were tested by STR-PCR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "growth", ...
PMC9429973	The cell viability was tested simultaneously by trypan blue exclusion test and by flow cytometry with 7 -aminoactinomycin D (7-AAD) without lysing solution.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11730311	Results are presented as mean ± range of n = 3.Table 1Results from Schild regression analyses.pA2Schild slopehαCGRP8-37No modifications8.23 ± 0.110.94 ± 0.15hαCGRP8-37A36S8.78 ± 0.421.08 ± 0.23hαCGRP8-37N25K-C20DA-γGlu8.33 ± 0.290.98 ± 0.15hαCGRP8-37A36S, N25K-C20DA-γGlu8.17 ± 0.501.83 ± 0.53Experiments were performed ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10421378	Through adhesion, probiotic bacteria can competitively exclude or inhibit the attachment of pathogenic microorganisms to the intestinal epithelium.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Through", "adhesion", ",", "probi...
PMC11772585	Next, we sought to detect cSCC cell apoptosis following METTL1 knockdown.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Next", ",", "we", "sought", "to", "detect", "cSCC", "cell", "apoptosis", "...
PMC11122631	In addition, in silico tools were used to predict the possible effects of isolated compounds on human tumor cell lines and nitric oxide production, as well as the pharmacological potentials.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9895440	Then cells were rigorously resuspended using ice cold FACS buffer (PBS with 2% FCS, 5 mM EDTA, and 0.1% Sodium azide) and spun at 4 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11461874	After 48 h, 100 μg/mL cycloheximide was treated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "48", "h", ",", "100", "μg/mL", "cycloheximide", "was", "treated", "." ] } ]
PMC9341513	Example snapshot from simulations showing the CCND1-TAD in GM12878 cells (pale orange region).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Example", "snapshot", "from", "simulations", "showing", ...
PMC11400680	Cellular features: additionally, we also take into account other metrics that are crucial for cell analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cellular", "features", ":", "additionally", ...
PMC10568263	All experiments were performed in triplicate and the average was recorded.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "experiments", "were", "performed", "in", "triplicate", "and", "the", "average", ...
PMC11412752	In hepatocellular carcinoma tissues, the mRNA levels of genes involved in the cGAS-STING pathway are up-regulated .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "hepatocellular", "carcinoma", "tissues", ",...
PMC10914904	Curiously, MVP levels are reduced during IAV infection in the same cell line; however, the role of MVP in this process is unclear .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9844987	All 108 LCLs were grown unsynchronized for 5–7 passages and harvested when they reached>20million cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "108", "LCLs", "were", "grown", "unsynchronized", "fo...
PMC11470381	The protocol was used and published in the following research article: Liu et al. .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "protocol", "was", "used", "and", "published", "in", ...
PMC11618052	Compounds 8g and 8h were further examined as activators of caspases 3, 8, and Bax and down-regulators of the anti-apoptotic protein Bcl2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9780037	Acidic environment inverts electrical charge causing the detachment of the gold nanoparticles and the release of cyt c (Figure 3F).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Acidic", "en...
PMC9429973	Summary/Conclusion: Patients in the early period after HSCT have a higher risk of developing lower respiratory tract infection, more likely to require antifungals, reserve group antibiotics, and have a greater risk of death from COVID-19.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10419319	Although isoalantolactone has a therapeutic effect on the recovery of chemoresistance through alteration in glucose metabolism and survival signaling pathways, further studies are required to clarify their relationship and the exact mechanism of isoalantolactone.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11185260	However, adding scL-vec to cisplatin treatment did not increase the Annexin V fraction compared with cisplatin monotherapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "adding", "scL-vec", "t...
PMC11644761	Additionally, pterostilbene alters DNA methylation patterns.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "pterostilbene", "alters", "DNA", "methylation", "patterns", "." ] } ]
PMC9429973	Image: Summary/Conclusion: Magrolimab + AZA was well tolerated with promising efficacy in pts with untreated HR MDS, including those with TP53-mutated and –wild-type disease.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10073922	LX-2 has been used in some studies to determine tumor specificity of some promoters .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "LX-2", "has", "been", "used", "in", "some", "studies", "to", ...
PMC11392912	The sequence of Stem-loop primer and Clo-miR-14 were as follows: Stem-loop primer for Clo-miR-14 (5-GTCGTATCCAGTGCAGGGTCCGAGGTATTCGCACTGGATACGACGCCTGGG-3) , Clo-miR-14 (5′-CGGCGGCTACTGTGAGTTTCC-3′, 5-GTCGTATCCAGTGCAGG GTCC-3′).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC8567602	L1 and L2 refer to the lobes by which SMARCA2/4 translocates DNA around the nucleosome.)	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "L1", "and", "L2", "refer", "to", "the", "lobes",...
PMC10719213	Hence, to mimic slow cell depletion in this culture system, 5 nM cladribine for 4 days was selected.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hence", ",", "to", "mi...
PMC9429973	Aims: This study investigated if a machine learning approach utilizing real world data from aHL patients can outcompete the IPS in predicting overall survival (OS).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10999934	Then, we had an intersection of three DEGs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", "we", "had", "an", "intersection", "of", "three", "DEGs", "." ] } ]
PMC9275501	Cell uptake and localization studies showed that MSNs with a layer of polyethylene glycol lipid bilayer could effectively carry drugs into cancer cells with sustained release characteristics, reduce the clinical dosage of the drug, reduce its side effects, and showed good targeting characteristics for breast cancer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11306331	Scale bar: 10 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", ":", "10", "μm", "." ] } ]
PMC11764090	But there are still few corresponding hormone fertilizers for cold stress, so further research is necessary for the construction and mining of the cold stress network.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11711063	In contrast, Bex + Carv inhibited colony formation, reduced Ki67 levels, ZG16B expression and glucose uptake in MDA‐MB231 xenografts.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "In", ...
PMC5311252	Unsupervised cluster analysis of the LUAD and BRCA gene expression profiles was performed using the 275 genes of the oncomotif-miRNA signature.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Unsupervised", "cluster...
PMC11180402	G–H Colony images in soft agar with/without ISO treatment (G), and colony count per 10 cells (H).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11519583	Cells were solubilized with lysis buffer (50 mM Tris-HCl [pH 7.5], 150 mM NaCl, 0.5% [v/v] Nonidet P-40, 5 mM EDTA, 50 mM NaF, 1 mM Na3VO4, 10 μg/ml aprotinin [Takara Bio], 10 μg/ml leupeptin [PEPTIDE INSTITUTE, INC.],	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11461874	j Control and TRAF7 KO NIH3T3 cells were transiently transfected with plasmids for DN mutant of UBE2G1/UBE2T together with expression plasmids for Flag-DBP.	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "token...
PMC9429973	I. Hortensia-Marioara, I. Ionita, I. Claudiu, D. Calamar Popovici, M. Ionita, D. Oros Spitalul Clinic Municipal de Urgenta, Timișoara, Romania Background: Autoimmune hemolytic anemia (AIHA) is characterized by the production of autoantibodies to red blood cell surface antigens with destruction of red blood cells by com...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7039683	Three independent biological replicates were subjected to RNA-seq profiling.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Three", "independent", "biological", "replicates", "were", "subjected", "to", "RNA-seq", "profiling", "." ...
PMC11470999	The data indicated that PF significantly inhibited lung metastasis growth, outperforming TMZ (Figure 2D,F,H).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "data", "in...
PMC11739484	Quantification of wound healing at 24 hours. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Quantification", "of", "wound", "healing", "at", "24", "hours", ".", "(" ] } ]
PMC9920575	Then, the cells were centrifuged, and the supernatant was transferred onto 96-well plates (Corning Costar, St. Louis, MO, USA) with 2X Reaction Buffer 8 and a colorimetric substrate of caspase-8.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11635087	Scale bar, 20 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", ",", "20", "μm", "." ] } ]
PMC10743717	would accelerate the oxidative inactivation of the protective neurosteroid, 17β-estradiol (see Figure 10) and thus be harmful to the function and structure of brain mitochondria.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11747467	RC48 (Remegen, China) was injected via the tail vein at a dose of 10 mg/kg per mouse, once or twice a week.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9318744	Several cell culture models are available for monitoring SARS-CoV-2 infection and pseudotyped virus activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Several", "cell", "culture", "models", "are", "available", "for", ...
PMC6364197	On one hand, we think that the bionic 3D scaffold with the capability of supporting the leukemic cells for a longer period has immense potential in drug screening.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6461034	Both TiO2 capture data (CRC, PXD001550; Piersma et al, 2015) and pTyr antibody capture data (pancreatic ductal adenocarcinoma, PDAC; PXD003198; Humphrey et al, 2016) were included.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11049294	Data showing a normal distribution an unpaired Student’s t-test, for a multiparametric analysis ANOVA test following Bonferroni correction, were used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", ...
PMC9429973	Following stimulation with ODN 2006, 25/42 (60%) patient samples showed an increase in CLL cell migration (‘Responders’) and 17/42 (40%) showed either no change or a decrease in CLL cell migration (‘Non/Reverse Responders).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11300639	KEGG and GSEA analysis were performed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "KEGG", "and", "GSEA", "analysis", "were", "performed", "." ] } ]
PMC11747467	Under STAT3-silencing conditions, RC48 significantly inhibited cell growth ( Figure 5C ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Under", "STAT3-silencing", "conditions", ",", "RC48", "significantly", "inhibited...
PMC9429973	RT-PCR was performed according to European recommendations, as described previously.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RT-PCR", "was", "performed", "according", "to", "European", "recommendations", ",", "as", ...
PMC9583612	First, we use CEMS to record ambient methane concentrations at participating facilities.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "First", ",", "we", "use", "CEMS", "to", "record", "ambient", "methane...
PMC9429973	Palliative treatment with blood products was used in the study patients during the 6 months prior to their death, with a median of 261.5 cubic centimeters (cc) (IQR 242 - 293) of doses of blood products and a median of 1 unit (IQR 1-2) transfused per patient.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Safety and efficacy data support the evaluation of mitapivat in children with PK deficiency who are not regularly transfused.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Safety", "and", "efficacy", "data...
PMC10452486	B27 mutants with C can generate S-S bonds with intra-chain cysteines of the α2 and α3 domains; however, these misfolded forms may not exit the ER in human cells (114).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11279598	Independent reports have provided evidence that honey such as Manuka honey exerts anti-proliferative effects against several types of cancer cells in vitro .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Independent", ...
PMC11267830	Flow cytometric analysis of the liver, spleen, and bone marrow from the mice stained with a human CD45+ antibody revealed a significant decrease in the percentage of cells that were positive for J.gamma1, underscoring the efficacy of the drug in these tissues (Fig. 3f).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11772585	Collectively, these findings support the conclusion that METTL1 functions as an oncogene in cSCC.Fig.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Collectively", ",", "these", "findings", "support", "the", ...

PMC11705067

A venn diagram of differentially expressed genes was created using the online tool Venny2.1.0, and the heatmap and volcano plot of differential expression genes about the gene expression profiles in the GSE53757 and GSE66272 databases were drawn by R software (version 4.0.3; R Foundation).

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PMC11206502

Meanwhile, cisplatin-based adjuvant chemotherapy remains a valid option for muscle-invasive bladder cancer .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Meanwhile", ",", "cisplatin-based", "adjuvant", "chemotherapy", "remains", "a", ...

PMC11748335

BEDtools was used for excluding regions within the blacklist .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "BEDtools", "was", "used", "for", "excluding", "regions", "within", "the", "blacklist", "." ] } ]

PMC11653533

Also, β-sitosterol, β-amyrin, and lupiol acetate were isolated from the stem bark of F. glomerata have manifested hypoglycemic potency by activating glucose-6-phosphate dehydrogenase enzyme with an enzyme activity of 273.20, 212.00 and 239.00 unit/min.

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PMC11670407

a-d To maintain cell number consistency, we transfected 143B or U2OS cells with the indicated siRNAs and overexpression plasmids for 48 h, followed by treatment with MG132 (10 μM) for 6 h before harvesting the cells.

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PMC7192625

XRCC6BP1 (ATP23) is a gene involved in DNA break repair, often amplified in glioblastoma.

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PMC11528603

Interestingly, Le-Trung et al. recently isolated acetylmelodorinol (AM) from the ethyl acetate fraction of S. affinis seeds.

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PMC6742971

Therefore, we compared the T cell's function in experiments using T cell clones with defined avidity, by using them individually and in parallel to mixtures of T cell cones with different avidities.

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PMC9429973

Despite there were no significant differences between the groups of patients with MDS, platelets from patients without AD showed a clear decrease in their ability to be activated by TRAP and was almost absent in three of them.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11723947

To characterize the gene networks that HP1α regulates, we next used deep total RNA-sequencing (RNA-seq) to analyze the transcriptomes of wild-type and mutant cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11583010

T47D (ATCC) and HCT-116 (Horizon Discovery, Perkin Elmer) were cultured in RPMI medium supplemented with 10% FBS.

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PMC7215722

These membranes are liquid-ordered lipid–protein assemblies enriched in cholesterol and sphingolipids that float within the liquid-disordered bilayer of cellular membranes .

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PMC11144200

K, L Representative fluorescence microscopy images of Hep3B or A-427 cells after incubation with LPS-RGD-Nb36-DOX for 2 h, 4 h, and 6 h, respectively.

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PMC11204465

This paper reviews the structures, biological activities, biosynthetic pathways, and chemical total synthesis of AFs and STCs.

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PMC11791264

Error bars represent the mean ± SD (n = 3).

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PMC11258145

The integrity of the HL-60 and SK-N-SH membranes after exposure to different concentrations of curcumin was determined by measuring the amount of released lactate dehydrogenase (LDH).

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PMC11621493

I–K) Total MAG, DAG, and TAG levels calculated based on the sum of signals from all detected subspecies.

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PMC11701801

The ON-TARGETplus SMARTPool siRNAs specific for target genes CREBBP (L-003477-00), EP300 (L-003486-00), KREMEN2 (L-003847-00), and KREMEN1 (L-003846-00) were purchased from Dharmacon.

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PMC11482552

In the majority of assays which include an IC, this is associated with the qualitative detection of a Beta-globin gene target, used to assess both the presence of human cells in the sample as well as any potential PCR inhibition in the same reaction well used for the detection of HPV DNA targets.

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PMC11472639

Additionally, ADCCPlasma post-exercise (34.1%) was significantly greater than ADCCHI-FCS post-exercise (23.3%) (t(7) = 3.72, p = 0.007, d = 1.31), with a trend towards a difference pre-exercise (t(7) = 2.10, p = 0.07, d = 0.75).Fig.

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PMC11787355

Top two gRNAs without self-complementarity were selected and cloned into the lentiCRISPRv2blast construct (Addgene #83480; RRID:Addgene 83480).

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PMC11543885

Wash with 2 mL quencher buffer per well for another two times, each wash lasting 1 min.

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PMC3019555

qRT-PCR was performed using iQ SYBR green supermix (Bio-Rad Laboratories) and the following specific primers: HIF-1α (forward, 5′-TGGTGACATGATTTACATTTCTGA-3′; reverse, 5′-AAGGCCATTTCTGTGTGTAAGC-3′), GAPDH (forward, 5′-GGAGTCAACGGATTTGGTCG-3′; reverse, 5′-CTTGATTTTGGAGGGATCTCG-3′), or p53 (forward, 5′-TCACAGCACATGACGGAG...

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PMC9429973

6% vs. 17%, p=0.3, Fig. 1D).

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PMC11770130

LD-independent SNPs from corresponding GWAS that passed the same SNP filtering and proxy search steps mentioned previously were used as instrument variables.

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PMC9080589

Differences between multiple groups were analyzed by ANOVA followed by Tukey's post hoc test.

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PMC9429973

The primary endpoint was mean change from baseline in QTc.

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PMC10577955

After ALUP, BA, and LUP treatment, cells were aggregated at the G2/M phase, thus we tried to measure the number of cells in each stage of apoptosis.

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PMC9429973

We have established a workflow to initiate germline genetic testing in pts under suspicion for a HHD.

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PMC11544122

Similar to CXCR4, most GPCRs are robustly phosphorylated on their CTs, including the prototypical GPCRs, which use the β-arrestin mode for endocytosis, such as β2AR, AT1AR, and V2R (Fig. 4c).

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PMC11707832

Post-translational modifications of MAN2B1 polypeptides occur within the endoplasmic reticulum.

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PMC11711935

Wnt inhibitory factor‐1 (WIF‐1) can also promote melanin synthesis in melanocytes.

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PMC10899471

qPCR analysis of MET expression in HT-1080 cells transfected with control or miR-939 mimic or inhibitor. *

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PMC10898159

These findings indicate the potential of PBOX-15 to improve the apoptotic response of IM in GIST cells and provide a more effective treatment option for GIST patients.

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PMC11763111

According to earlier research, off-the-shelf CAR-T cells do not overproliferate and produce CRS.

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PMC9429973

The percentage of JAK2 positive patients in patients with a score of 1-3 was 24% versus 0.8% in patients with a score of 0.

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PMC11806106

After application of a non-saturating concentration of DAMGO, the signal was reversible by application of the antagonist naloxone (Supplementary Fig. 3B) and application of extracellular buffer induced no change in BRET ratio (Supplementary Fig. 3C).Fig.

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PMC11413393

n = 5 mice/group (RCC243_NT shRNA (+)Dox, RCC243_PRMT1 shRNA (+)Dox and 786-0_PRMT1 shRNA (+)Dox) and n = 3 mice/group (RCC243_PRMT1 shRNA (-)Dox, 786-0_NT shRNA (+)Dox and 786-0_PRMT1 shRNA (-)Dox).

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PMC10329074

For instance, YBX3 promoted the metastasis of nasopharyngeal carcinoma via PI3K/AKT signaling (Fan et al. 2021).

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PMC11750712

The gating strategy is available in the Supplementary Information.

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PMC9429973

In summary, our study uncovers how the TME can contribute to leukemic transformation which provides alternative avenues for therapeutic interventions.

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PMC10048572

After growth cells were re-cloned by the limiting dilutions, 180 B4 subclones and 381 O1 subclones were tested by STR-PCR.

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PMC9429973

The cell viability was tested simultaneously by trypan blue exclusion test and by flow cytometry with 7 -aminoactinomycin D (7-AAD) without lysing solution.

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PMC11730311

Results are presented as mean ± range of n = 3.Table 1Results from Schild regression analyses.pA2Schild slopehαCGRP8-37No modifications8.23 ± 0.110.94 ± 0.15hαCGRP8-37A36S8.78 ± 0.421.08 ± 0.23hαCGRP8-37N25K-C20DA-γGlu8.33 ± 0.290.98 ± 0.15hαCGRP8-37A36S, N25K-C20DA-γGlu8.17 ± 0.501.83 ± 0.53Experiments were performed ...

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PMC10421378

Through adhesion, probiotic bacteria can competitively exclude or inhibit the attachment of pathogenic microorganisms to the intestinal epithelium.

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PMC11772585

Next, we sought to detect cSCC cell apoptosis following METTL1 knockdown.

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PMC11122631

In addition, in silico tools were used to predict the possible effects of isolated compounds on human tumor cell lines and nitric oxide production, as well as the pharmacological potentials.

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PMC9895440

Then cells were rigorously resuspended using ice cold FACS buffer (PBS with 2% FCS, 5 mM EDTA, and 0.1% Sodium azide) and spun at 4 °C.

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PMC11461874

After 48 h, 100 μg/mL cycloheximide was treated.

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PMC9341513

Example snapshot from simulations showing the CCND1-TAD in GM12878 cells (pale orange region).

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PMC11400680

Cellular features: additionally, we also take into account other metrics that are crucial for cell analysis.

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PMC10568263

All experiments were performed in triplicate and the average was recorded.

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PMC11412752

In hepatocellular carcinoma tissues, the mRNA levels of genes involved in the cGAS-STING pathway are up-regulated .

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PMC10914904

Curiously, MVP levels are reduced during IAV infection in the same cell line; however, the role of MVP in this process is unclear .

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PMC9844987

All 108 LCLs were grown unsynchronized for 5–7 passages and harvested when they reached>20million cells.

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PMC11470381

The protocol was used and published in the following research article: Liu et al. .

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PMC11618052

Compounds 8g and 8h were further examined as activators of caspases 3, 8, and Bax and down-regulators of the anti-apoptotic protein Bcl2.

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PMC9780037

Acidic environment inverts electrical charge causing the detachment of the gold nanoparticles and the release of cyt c (Figure 3F).

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PMC9429973

Summary/Conclusion: Patients in the early period after HSCT have a higher risk of developing lower respiratory tract infection, more likely to require antifungals, reserve group antibiotics, and have a greater risk of death from COVID-19.

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PMC10419319

Although isoalantolactone has a therapeutic effect on the recovery of chemoresistance through alteration in glucose metabolism and survival signaling pathways, further studies are required to clarify their relationship and the exact mechanism of isoalantolactone.

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PMC11185260

However, adding scL-vec to cisplatin treatment did not increase the Annexin V fraction compared with cisplatin monotherapy.

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PMC11644761

Additionally, pterostilbene alters DNA methylation patterns.

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PMC9429973

Image: Summary/Conclusion: Magrolimab + AZA was well tolerated with promising efficacy in pts with untreated HR MDS, including those with TP53-mutated and –wild-type disease.

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PMC10073922

LX-2 has been used in some studies to determine tumor specificity of some promoters .

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PMC11392912

The sequence of Stem-loop primer and Clo-miR-14 were as follows: Stem-loop primer for Clo-miR-14 (5-GTCGTATCCAGTGCAGGGTCCGAGGTATTCGCACTGGATACGACGCCTGGG-3) , Clo-miR-14 (5′-CGGCGGCTACTGTGAGTTTCC-3′, 5-GTCGTATCCAGTGCAGG GTCC-3′).

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PMC8567602

L1 and L2 refer to the lobes by which SMARCA2/4 translocates DNA around the nucleosome.)

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PMC10719213

Hence, to mimic slow cell depletion in this culture system, 5 nM cladribine for 4 days was selected.

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PMC9429973

Aims: This study investigated if a machine learning approach utilizing real world data from aHL patients can outcompete the IPS in predicting overall survival (OS).

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PMC10999934

Then, we had an intersection of three DEGs.

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PMC9275501

Cell uptake and localization studies showed that MSNs with a layer of polyethylene glycol lipid bilayer could effectively carry drugs into cancer cells with sustained release characteristics, reduce the clinical dosage of the drug, reduce its side effects, and showed good targeting characteristics for breast cancer.

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PMC11306331

Scale bar: 10 μm.

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PMC11764090

But there are still few corresponding hormone fertilizers for cold stress, so further research is necessary for the construction and mining of the cold stress network.

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PMC11711063

In contrast, Bex + Carv inhibited colony formation, reduced Ki67 levels, ZG16B expression and glucose uptake in MDA‐MB231 xenografts.

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PMC5311252

Unsupervised cluster analysis of the LUAD and BRCA gene expression profiles was performed using the 275 genes of the oncomotif-miRNA signature.

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PMC11180402

G–H Colony images in soft agar with/without ISO treatment (G), and colony count per 10 cells (H).

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PMC11519583

Cells were solubilized with lysis buffer (50 mM Tris-HCl [pH 7.5], 150 mM NaCl, 0.5% [v/v] Nonidet P-40, 5 mM EDTA, 50 mM NaF, 1 mM Na3VO4, 10 μg/ml aprotinin [Takara Bio], 10 μg/ml leupeptin [PEPTIDE INSTITUTE, INC.],

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PMC11461874

j Control and TRAF7 KO NIH3T3 cells were transiently transfected with plasmids for DN mutant of UBE2G1/UBE2T together with expression plasmids for Flag-DBP.

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PMC9429973

I. Hortensia-Marioara, I. Ionita, I. Claudiu, D. Calamar Popovici, M. Ionita, D. Oros Spitalul Clinic Municipal de Urgenta, Timișoara, Romania Background: Autoimmune hemolytic anemia (AIHA) is characterized by the production of autoantibodies to red blood cell surface antigens with destruction of red blood cells by com...

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PMC7039683

Three independent biological replicates were subjected to RNA-seq profiling.

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PMC11470999

The data indicated that PF significantly inhibited lung metastasis growth, outperforming TMZ (Figure 2D,F,H).

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PMC11739484

Quantification of wound healing at 24 hours. (

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PMC9920575

Then, the cells were centrifuged, and the supernatant was transferred onto 96-well plates (Corning Costar, St. Louis, MO, USA) with 2X Reaction Buffer 8 and a colorimetric substrate of caspase-8.

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PMC11635087

Scale bar, 20 μm.

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PMC10743717

would accelerate the oxidative inactivation of the protective neurosteroid, 17β-estradiol (see Figure 10) and thus be harmful to the function and structure of brain mitochondria.

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PMC11747467

RC48 (Remegen, China) was injected via the tail vein at a dose of 10 mg/kg per mouse, once or twice a week.

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PMC9318744

Several cell culture models are available for monitoring SARS-CoV-2 infection and pseudotyped virus activity.

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PMC6364197

On one hand, we think that the bionic 3D scaffold with the capability of supporting the leukemic cells for a longer period has immense potential in drug screening.

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PMC6461034

Both TiO2 capture data (CRC, PXD001550; Piersma et al, 2015) and pTyr antibody capture data (pancreatic ductal adenocarcinoma, PDAC; PXD003198; Humphrey et al, 2016) were included.

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PMC11049294

Data showing a normal distribution an unpaired Student’s t-test, for a multiparametric analysis ANOVA test following Bonferroni correction, were used.

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PMC9429973

Following stimulation with ODN 2006, 25/42 (60%) patient samples showed an increase in CLL cell migration (‘Responders’) and 17/42 (40%) showed either no change or a decrease in CLL cell migration (‘Non/Reverse Responders).

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PMC11300639

KEGG and GSEA analysis were performed.

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PMC11747467

Under STAT3-silencing conditions, RC48 significantly inhibited cell growth ( Figure 5C ).

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PMC9429973

RT-PCR was performed according to European recommendations, as described previously.

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PMC9583612

First, we use CEMS to record ambient methane concentrations at participating facilities.

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PMC9429973

Palliative treatment with blood products was used in the study patients during the 6 months prior to their death, with a median of 261.5 cubic centimeters (cc) (IQR 242 - 293) of doses of blood products and a median of 1 unit (IQR 1-2) transfused per patient.

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PMC9429973

Safety and efficacy data support the evaluation of mitapivat in children with PK deficiency who are not regularly transfused.

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PMC10452486

B27 mutants with C can generate S-S bonds with intra-chain cysteines of the α2 and α3 domains; however, these misfolded forms may not exit the ER in human cells (114).

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PMC11279598

Independent reports have provided evidence that honey such as Manuka honey exerts anti-proliferative effects against several types of cancer cells in vitro .

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PMC11267830

Flow cytometric analysis of the liver, spleen, and bone marrow from the mice stained with a human CD45+ antibody revealed a significant decrease in the percentage of cells that were positive for J.gamma1, underscoring the efficacy of the drug in these tissues (Fig. 3f).

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PMC11772585

Collectively, these findings support the conclusion that METTL1 functions as an oncogene in cSCC.Fig.

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