OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11697065	B: A schematic detailing stable CHO cell pool generation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ "B", ":", "A", "schematic", "detailing", "stable", "CHO", "cell", "pool", "generation", ...
PMC11621493	Peak areas and lipid labels were manually curated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Peak", "areas", "and", "lipid", "labels", "were", "manually", "curated", "." ] } ]
PMC11748335	Motifs are ranked by their occurrence across multiple normal-tumor pairs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Motifs", "are", "ranked", "by", "their", "occurrence", "across", "multiple", "normal-tumor", "pa...
PMC11792766	The passage number was kept below 30 for HepG2 and between 20 and 40 for Caco‐2 cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "The", "passage", "number", ...
PMC10809689	Other metabolic pathways could be a priority in THP-1 cells to provide biomass energy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Other", "metabolic", "pathways", "could", "be", "a", "priorit...
PMC11506670	TNTs have been shown to facilitate intercellular transport of RNA transcripts, proteins, and even organelles such as mitochondria, to instigate an oncogenic program or promote survival of damaged cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7987994	We incubated the cells with simulated extracts (ZnCl2 solutions) and determined their toxicity at various conditions of the test.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "incubated", ...
PMC6182045	The first method reconstructed the method used to purify the rgp120 immunogens used in the RV144 clinical trial (3) and incorporated an affinity chromatography column that purified gp120 via an N-terminal gD tag as previously described (13).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Results: The frequency of occurrence of thrombophilia and prothrombotic genes polymorphism are presented in the Table.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "The", "frequency", "of", "o...
PMC11763126	These compounds offer notable advantages, including high specificity, facile synthesis, small molecular sizes, modifiability, and excellent biocompatibility, rendering them highly promising for targeted therapeutic applications .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11763111	The cytotoxicity of 4KO CAR-T cells against CCRF-CEM cells was comparable to that of 1KO CAR-T cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cytotoxicity", "of", "4KO", "CAR-...
PMC10778532	It was also reported in 786-0 cells (VHL−/−) treated with sunitinib, an induction of EMT markers via activation of EGFR .	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC9351137	A set of 5 random background areas from the same image were used to normalize the integrated intensity of the specific signal.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "set", ...
PMC9429973	Results: Median hsa-miR-16 expression at diagnosis was 0.23 and 0.64 at relapse.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "Median", "hsa-miR-16", "expression", "at", "diagnosis", "wa...
PMC11419566	Moreover, PA could also induce apoptosis in cancer cells in other ways (Fig. 1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "PA", "could", "also", "ind...
PMC9105697	The minimal limit of detection was determined at a variant allele frequency of 0.05%.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "minimal", "limit", "of", "detection", "was", "determ...
PMC4485648	Thereby it contributes to pericellular acidosis, which supports cell migration and invasion (21).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thereby", "it", "contributes", "to", "pericellular", "...
PMC11730000	The ability of RA to scavenge radiation-induced reactive oxygen species (ROS).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "ability", "of", "RA", "to", "scavenge", "radiation-induced", "reacti...
PMC9895440	h IFNγ secretion measured by ELISA after 4 days co-culture of Teff or Tex with MDA-MB-231 cells loaded with 100 nM NY-ESO-1-9V peptide in presence of either 10 μg/ml human IgG4 isotype control or anti-PD-1 antibody (Nivolumab).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11528603	All of the chemicals used for these assays were purchased from Xilong Chemical (China).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "of", "the", "chemicals", "used", "for", "...
PMC11741906	Another major approach to study miRNAs’ role in cisplatin treatment response is comparing specific miRNA expression between cisplatin-sensitive and cisplatin-resistant variants of ovarian cancer cell lines using qPCR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11687167	Compared with the placebo, evolocumab treatment significantly reduced the risk of cardiovascular death, myocardial infarction, hospitalization for unstable angina, and coronary revascularization (p < 0.001) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8633974	Extraction of this excised amplicon followed by Sanger sequencing was deployed to validate the CRISPR editing.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Extraction", "of", "this", "excised", "amplicon", "fol...
PMC11604768	All TRE unit oligonucleotides, except those encoding positive control TREs greater than 160 nucleotides, were synthesized as 160 nucleotides in length by adjusting sequence lengths 3’ to the TRE unit to limit bias in PCR amplification prior to library assembly.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9250505	Live/Dead cells visualization was performed as per the manufacturer’s instructions using LIVE/DEAD™ Cell Imaging Kit (Thermo Fisher Scientific, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11615218	T cells are crucial components of the anti-tumor immune response, and multiple intrinsic T-cell features significantly influence the outcomes of CAR-T cell therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11731614	Each fraction is run through a 3–15% gradient gel (BioRad 45610840) alongside full keratinocyte cell lysate (+) and a 10K pellet (large EVs), running a BCA assay (Thermo Scientific) to load ∼3 μg of protein per well.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11597167	DMSO, the solvent for dissolving the phenolic compounds, was used as the control group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "DMSO", ",", "the", "solvent", "for", "dissolving", ...
PMC8759873	The protein product produced by the VHL gene encoding is called protein VHL (pVHL).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "protein", "product", "produced", "by", "the", ...
PMC11337594	The results demonstrate that TER can block the cell cycle of A375 cells in G2 and S phases, which may be related to the decreased expression of Cyclin A2 induced by p53.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11734514	Wound healing and invasion assays were performed to measure the migration and invasion capabilities of A549 cells post-treatment with C. aerizusa extract.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Wound", ...
PMC8998437	Up to now, not much is known about the impact of EBV on eBL disease progression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Up", "to", "now", ",", "not", "much", ...
PMC9398137	The role of MCL1 in lymphoma pathogenesis was well demonstrated by MCL1 transgenic mouse models.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "role", "of", "MCL1", "in", "lymphoma", "pathogenesis...
PMC11656657	L The graph shows the modulation of the distribution of CD4 + and CD8 + subpopulations of CAR.GD2 T-cells before (day 0) and after RD tumor cell addition at day + 5, + 10, + 15 and + 20.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11267830	c PCR analysis of EZH2 and THOC1 in primary cells treated with indisulam.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "c", "PCR", "analysis", "of", "EZH2", "and", "THOC1", "in", "primary",...
PMC11748618	Overlapping colored bars represent chromatin states obtained from ENCODE (African PBMC: ENCFF863IVL; European PBMC: ENCFF235OWS; African LCLs: ENCFF747OPJ; European LCLs: ENCFF070KWN).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6222635	F3 up-regulated the expression of the p38 gene in HeLa cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "F3", "up-regulated", "the", "expression", "of", "the", "p38", "gene", "in", ...
PMC9473868	BAI upregulated apoptotic proteins and downregulated EMT-related proteins, resulting in enhanced cell apoptosis and inhibited cell migration in SW982 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "BAI", "upregul...
PMC10758402	n>5, mean ± SD; ns = no significance, P< 0.05, p < 0.01, p < 0.001 and **P<0.0001 by two-tailed t-test).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7841189	The primary antibodies used were mouse anti-LTBP2 (1:1,000), mouse anti-E-cadherin (1:2,500), mouse anti-N-cadherin (1:1,500), mouse anti-vimentin (1:3,000), mouse anti-PI3K (1:2,000), mouse anti-p-PI3K (1:2,000), mouse anti-Akt (1:3,000), mouse anti-p-Akt (1:3,000), and mouse anti-GAPDH (1:3,000).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10812665	For instance, ornithine (Orn), asparagine (Asn), glutamine (Gln) and serine (Ser) were increased, while aspartate (Asp) and glutamate (Glu) were depleted.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9895440	These experiments indicate that SNX9 may be implicated in regulating T cell activation at the immune synapse.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "experiments", "indicate", "that", "SNX9"...
PMC9429973	Finally, immunological studies performed using bone marrow samples from a patient and an unrelated control showed a reduction in the number of mature B cells, suggesting a block of the B-cell differentiation at the pre-B stage in the patient.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11371627	The transport and expression of recombinant Kell and XK protein in CV-1 in origin carrying SV40 (COS) cells in in vivo experiments appeared to be independent of the other protein (Russo et al., 1999), but clinical reports have shown that Kell protein expression and Kell antigen presentation are significantly diminished...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "...
PMC11604768	Differential promoter activities relative to vehicle-treated cells transfected with the library were determined using MPRAnalyze.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Differential", "promoter", "activities", "relative", "to", "vehic...
PMC10551595	Informed Consent: All the patient parents were informed about the purposes of the study and consequently have signed their consents.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Informed", "Consent", ...
PMC11723947	P values were calculated using multiple unpaired t-tests with Holm-Šidák correction.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P", "values", "were", "calculated", "using", "multiple", "unpaired", "t-tests", "with", ...
PMC8751435	Caspase‐3‐dependent pyroptosis, which is inflammation‐involved PCD and one of the downstream pathways of reactive oxygen species (ROS), is increasingly recognized as critical pathways for PCD beyond apoptosis (Wang et al., 2017).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11185260	We anticipate a similar distribution of exogenous SMARCB1 protein in the nucleus and cytosol.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "anticipate", "a", "similar", "distribution", "of", "exogenous", ...
PMC9429973	Warfarin only was the preferred long-term anticoagulant (53%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Warfarin", "only", "was", "the", "preferred", "long-term", "anticoagulant", "(", "53", ...
PMC8735881	Next, the target cells (2.5 × 10 /well) were added to effector cells, spun down to maximize cell–cell contact, and cocultured for 6 h. The fusion activity between the target and effector cells was measured by quantifying the production of the reporter luciferase as described above.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11790971	Each field of view (FOV) contained 512 × 512 pixels, covering an area of 180 × 180 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", "field", "...
PMC11343332	Gene expression analysis by real-time PCR The gene expression of apoptotic and VEGF/FGF genes was analyzed using real-time PCR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Gene", "expression", "analysis", ...
PMC11745823	High c‐Myc expression is closely correlated with various cancers (such as breast cancer , liver cancer and lymphoma ) because it can enhance rapid cell proliferation and impede cell apoptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5673060	Phosphosites that display at least 2-times increase in PazR (red) or increase in A204 parental (blue) with p < 0.05 are indicated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11703992	The results showed that various diseases or phenotypes were associated with the SNP, including rheumatoid arthritis and ulcerative colitis, as described in Table S3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973	IGLV3-21 had also a prognostic impact on OS since M-CLL carrying the IGLV3-21 had shorter OS similar to that of U-CLL (Figure).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11412721	Means ± SEM from four independent experiments. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Means", "±", "SEM", "from", "four", "independent", "experiments", ".", "(" ] } ]
PMC3931643	A key upstream regulator of eIF4E is the serine/threonine kinase mTOR –. Elevated mTOR activity is a prominent feature of cancer cells, including hematological malignancies .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC5854676	Electrostatic interactions between magnetic hybrid nano-carriers (e.g., dendrimer complexes) show morphological features that are desired in various biomedical applications, especially nucleic acid therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7229095	Final overall evaluation was made with the clones obtained from CLD of CDM1 platform and CDM2 platform.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Final", "overall", "evaluation", "was", "made", ...
PMC6803987	From the above, there have been a few studies on the substance’s anti-HBV activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "From", "the", "above", ",", "there", "have", "be...
PMC9352806	E. coli HT115 (DE3) harboring empty vector L4440 or expressing double stranded RNA corresponding to hlh-30 was transferred into LA broth containing isopropyl 1-thio-β-d-galactopyranoside (IPTG, 5 mM).	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11791432	Tumor-derived annexin A1 (ANXA1) has been reported to promote the differentiation of macrophages and microglia .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tumor-derived", "annexin", "A1", "(", "ANXA1", ...
PMC11075223	It is suitable for growth in slightly acidic or neutral humus soil .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "suitable", "for", "growth", "in", "slightly", "acidic", "or", ...
PMC11228511	In our current studies, we matched progerin levels in cultured SMCs to levels in the aortas of Lmna mice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "our", "current", ...
PMC9429973	Multivariate analyses of other subgroups were not performed due to the low patient number with BCL2-R/MYC-R/BCL6-R. While patients with DEL treated with Pola-R-CHP had improved PFS vs patients treated with R-CHOP (HR 0.64, 95% CI 0.42–0.97), the prognostic impact of DEL vs non-DEL was identified in the R-CHOP arm (univ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10419319	Small molecules derived from natural products can exhibit various pharmacological properties, including anticancer activities .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Small", "molecules", "derived", "from", "natural", "products", ...
PMC10818573	However, this reaction system did not amplify the target bands (Figure 2C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "this", "reaction", "system", "did", "not", ...
PMC11705067	In the present study, we investigated the sensitivity of ccRCC to cuproptosis and applied comprehensive bioinformatics analysis to reveal the roles of cuproptosis-related genes FDX1 and DLAT in ccRCC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11297139	Scale bar: 5 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", ":", "5", "μm", "." ] } ]
PMC11577421	Second, the glycocalyx undergoes reorganization in response to shear flow, a condition encountered in vivo.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Second", ",", "the", "glycocalyx", "undergoes", ...
PMC7602170	Glycogen synthase kinase 3 (GSK3) can phosphorylate and activate TSC2, thereby inhibiting mTORC1 signal.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Glycogen", "synthase", "kinase", "3", "(", ...
PMC9429973	I. Urbino, E. Lengline, M. Cerrano, F. Rabian, R. Kim, M. Sebert, R. Itzykson, E. Audisio, L. Ades, H. Dombret, E. Raffoux, D. Ferrero, E. Clappier, N. Boissel Hematology Department, AOU Città della Salute e della Scienza di Torino, Torino, Italy; Hematology Department; Hematology Laboratory, Saint-Louis Hospital - Uni...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10723784	Further studies are required to investigate whether these results are translatable in the clinic.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Further", "studies", "are", "required", "to", "investigate", "whether"...
PMC11279598	While Manuka honey shares constituents (such as glucose oxidases) with other types of honey, it also contains other specific phytochemical factors that potentiate its biological activity, such as methylglyoxal .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11640555	As previously mentioned, CK2 promotes GBM cell adhesion, migration, and proliferation, through the activation of several signaling pathways (NF-κB, JAK/STAT, and PI3K/Akt).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6771295	The existence of differential micro-environmental conditions in osteosarcoma vs. mesothelioma cells that diversely affect the sirtuin family members mediated autophagy could be a potential explanation for these results.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11087055	K-L’’’) Vorticity plots, displaying an averaged measure of the local rotation during each time period.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "K-L", "’’", "’", ")", "Vort...
PMC11116779	The medium was replaced every 2 days.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "medium", "was", "replaced", "every", "2", "days", "." ] } ]
PMC11781181	In various diseases, enhanced exosome production in patients is closely associated with the disruption of cell death 31-34.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "various", "...
PMC11770199	Curves of tumor growth of colon cancer with the treatment of normal saline (NS), mMSCs-GFP, and mMSCs-p14.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Curves", "of", "t...
PMC11286266	ATF6α nuclear translocation live cell microscopy assay showing unstressed 2K parental cells and a 2K-CRT∆ clone.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ATF6α", "nuclear", "translocation", "live", "cell...
PMC10047551	The cell culture medium was replaced with a fresh medium containing AZA every day.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cell", "culture", "medium", "was", "replaced", "with", "a...
PMC10213179	Fluorescence microscopy: functionalization of the aptamer sequence with a Cy5 moiety was used to check for its localization within cells using a confocal microscope.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC8633974	Pearson correlation was chosen to measure whether the two variables (conservation and efficacy) were positively correlated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Pearson", "correlation", "was", "chosen", ...
PMC11753435	There exist approximately 10 possible 20-nucleotide oligomer peptides—far too large of a space to exhaustively screen either in silico or in vitro for a given target.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10243817	Collagen expression in eosinophilic CRSwNP was negatively correlated with MEX3B but positively correlated with TGF-βR3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Collagen", "expression", "in", "eosinophilic", "CRSwNP", "was", ...
PMC11306331	Cells with a high degree of FUS condensate formation have a high CV in pixel intensity, as they harbor both bright pixels within condensates and dark pixels between them.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5600151	Second, protection of nucleic acid from nuclease is one of the major concerns in nucleic acid delivery.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Second", ",", "protection", "of", "nuc...
PMC10968586	In fact, treatment of colon carcinoma RKO cell line with 20–80 μM OLE diminished cell viability in a dose-dependent fashion .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "fact", ...
PMC11762280	AIM2 is a common sensor that initiates inflammasomes, whereas ASC, as an adapter, is involved in multiple inflammasomes such as AIM2-, NLRP3-, and NLRP12-inflammasomes .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	In addition, we generated NFKBIE mice and crossed them with Em-TCL1 mice, a validated CLL mouse model, to generate immunocompetent Em-TCL1-NFKBIE.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10944868	This parameter provides insights into the energetics governing the ligand-receptor interaction.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "parameter", "provides", "insights", "into", "the", "energetics", "governing", "the"...
PMC11442172	The advent of co-culture systems has made it possible to incorporate multiple cell types to study metabolic cell-cell communication.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "advent", "of", "co-culture...
PMC11257988	Molecular chaperone Hsp 90 is essential for protein stability and maturation and prevents protein degradation by the proteasome.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Molecular", "chaperone", "Hsp", "90", ...
PMC11730000	In this study, mTOR levels were decreased in the EGCG-administered groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "this", "study", ",", "mTOR", "levels", "were", "decreased", "in", "t...
PMC11359735	A parallel blank lane was cut in an identical manner to use as negative controls for the experiment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "parallel", "blank", "lane", "was"...
PMC11496491	Red dots indicate up-regulated genes, green dots indicate down-regulated genes, and black dots indicate non-significant differentially expressed genes. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Red", "dots", "in...
PMC11705067	All antibodies were purchased from Abcam.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "antibodies", "were", "purchased", "from", "Abcam", "." ] } ]

PMC11697065

B: A schematic detailing stable CHO cell pool generation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ "B", ":", "A", "schematic", "detailing", "stable", "CHO", "cell", "pool", "generation", ...

PMC11621493

Peak areas and lipid labels were manually curated.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Peak", "areas", "and", "lipid", "labels", "were", "manually", "curated", "." ] } ]

PMC11748335

Motifs are ranked by their occurrence across multiple normal-tumor pairs.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Motifs", "are", "ranked", "by", "their", "occurrence", "across", "multiple", "normal-tumor", "pa...

PMC11792766

The passage number was kept below 30 for HepG2 and between 20 and 40 for Caco‐2 cell lines.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "The", "passage", "number", ...

PMC10809689

Other metabolic pathways could be a priority in THP-1 cells to provide biomass energy.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Other", "metabolic", "pathways", "could", "be", "a", "priorit...

PMC11506670

TNTs have been shown to facilitate intercellular transport of RNA transcripts, proteins, and even organelles such as mitochondria, to instigate an oncogenic program or promote survival of damaged cells .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7987994

We incubated the cells with simulated extracts (ZnCl2 solutions) and determined their toxicity at various conditions of the test.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "incubated", ...

PMC6182045

The first method reconstructed the method used to purify the rgp120 immunogens used in the RV144 clinical trial (3) and incorporated an affinity chromatography column that purified gp120 via an N-terminal gD tag as previously described (13).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Results: The frequency of occurrence of thrombophilia and prothrombotic genes polymorphism are presented in the Table.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "The", "frequency", "of", "o...

PMC11763126

These compounds offer notable advantages, including high specificity, facile synthesis, small molecular sizes, modifiability, and excellent biocompatibility, rendering them highly promising for targeted therapeutic applications .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11763111

The cytotoxicity of 4KO CAR-T cells against CCRF-CEM cells was comparable to that of 1KO CAR-T cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cytotoxicity", "of", "4KO", "CAR-...

PMC10778532

It was also reported in 786-0 cells (VHL−/−) treated with sunitinib, an induction of EMT markers via activation of EGFR .

[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...

PMC9351137

A set of 5 random background areas from the same image were used to normalize the integrated intensity of the specific signal.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "set", ...

PMC9429973

Results: Median hsa-miR-16 expression at diagnosis was 0.23 and 0.64 at relapse.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "Median", "hsa-miR-16", "expression", "at", "diagnosis", "wa...

PMC11419566

Moreover, PA could also induce apoptosis in cancer cells in other ways (Fig. 1).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "PA", "could", "also", "ind...

PMC9105697

The minimal limit of detection was determined at a variant allele frequency of 0.05%.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "minimal", "limit", "of", "detection", "was", "determ...

PMC4485648

Thereby it contributes to pericellular acidosis, which supports cell migration and invasion (21).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thereby", "it", "contributes", "to", "pericellular", "...

PMC11730000

The ability of RA to scavenge radiation-induced reactive oxygen species (ROS).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "ability", "of", "RA", "to", "scavenge", "radiation-induced", "reacti...

PMC9895440

h IFNγ secretion measured by ELISA after 4 days co-culture of Teff or Tex with MDA-MB-231 cells loaded with 100 nM NY-ESO-1-9V peptide in presence of either 10 μg/ml human IgG4 isotype control or anti-PD-1 antibody (Nivolumab).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11528603

All of the chemicals used for these assays were purchased from Xilong Chemical (China).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "of", "the", "chemicals", "used", "for", "...

PMC11741906

Another major approach to study miRNAs’ role in cisplatin treatment response is comparing specific miRNA expression between cisplatin-sensitive and cisplatin-resistant variants of ovarian cancer cell lines using qPCR.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11687167

Compared with the placebo, evolocumab treatment significantly reduced the risk of cardiovascular death, myocardial infarction, hospitalization for unstable angina, and coronary revascularization (p < 0.001) .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8633974

Extraction of this excised amplicon followed by Sanger sequencing was deployed to validate the CRISPR editing.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Extraction", "of", "this", "excised", "amplicon", "fol...

PMC11604768

All TRE unit oligonucleotides, except those encoding positive control TREs greater than 160 nucleotides, were synthesized as 160 nucleotides in length by adjusting sequence lengths 3’ to the TRE unit to limit bias in PCR amplification prior to library assembly.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9250505

Live/Dead cells visualization was performed as per the manufacturer’s instructions using LIVE/DEAD™ Cell Imaging Kit (Thermo Fisher Scientific, USA).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11615218

T cells are crucial components of the anti-tumor immune response, and multiple intrinsic T-cell features significantly influence the outcomes of CAR-T cell therapy.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11731614

Each fraction is run through a 3–15% gradient gel (BioRad 45610840) alongside full keratinocyte cell lysate (+) and a 10K pellet (large EVs), running a BCA assay (Thermo Scientific) to load ∼3 μg of protein per well.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11597167

DMSO, the solvent for dissolving the phenolic compounds, was used as the control group.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "DMSO", ",", "the", "solvent", "for", "dissolving", ...

PMC8759873

The protein product produced by the VHL gene encoding is called protein VHL (pVHL).

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PMC11337594

The results demonstrate that TER can block the cell cycle of A375 cells in G2 and S phases, which may be related to the decreased expression of Cyclin A2 induced by p53.

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PMC11734514

Wound healing and invasion assays were performed to measure the migration and invasion capabilities of A549 cells post-treatment with C. aerizusa extract.

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PMC8998437

Up to now, not much is known about the impact of EBV on eBL disease progression.

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PMC9398137

The role of MCL1 in lymphoma pathogenesis was well demonstrated by MCL1 transgenic mouse models.

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PMC11656657

L The graph shows the modulation of the distribution of CD4 + and CD8 + subpopulations of CAR.GD2 T-cells before (day 0) and after RD tumor cell addition at day + 5, + 10, + 15 and + 20.

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PMC11267830

c PCR analysis of EZH2 and THOC1 in primary cells treated with indisulam.

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PMC11748618

Overlapping colored bars represent chromatin states obtained from ENCODE (African PBMC: ENCFF863IVL; European PBMC: ENCFF235OWS; African LCLs: ENCFF747OPJ; European LCLs: ENCFF070KWN).

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PMC6222635

F3 up-regulated the expression of the p38 gene in HeLa cells.

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PMC9473868

BAI upregulated apoptotic proteins and downregulated EMT-related proteins, resulting in enhanced cell apoptosis and inhibited cell migration in SW982 cells.

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PMC10758402

n>5, mean ± SD; ns = no significance, *P< 0.05, **p < 0.01, ***p < 0.001 and ****P<0.0001 by two-tailed t-test).

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PMC7841189

The primary antibodies used were mouse anti-LTBP2 (1:1,000), mouse anti-E-cadherin (1:2,500), mouse anti-N-cadherin (1:1,500), mouse anti-vimentin (1:3,000), mouse anti-PI3K (1:2,000), mouse anti-p-PI3K (1:2,000), mouse anti-Akt (1:3,000), mouse anti-p-Akt (1:3,000), and mouse anti-GAPDH (1:3,000).

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PMC10812665

For instance, ornithine (Orn), asparagine (Asn), glutamine (Gln) and serine (Ser) were increased, while aspartate (Asp) and glutamate (Glu) were depleted.

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PMC9895440

These experiments indicate that SNX9 may be implicated in regulating T cell activation at the immune synapse.

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PMC9429973

Finally, immunological studies performed using bone marrow samples from a patient and an unrelated control showed a reduction in the number of mature B cells, suggesting a block of the B-cell differentiation at the pre-B stage in the patient.

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PMC11371627

The transport and expression of recombinant Kell and XK protein in CV-1 in origin carrying SV40 (COS) cells in in vivo experiments appeared to be independent of the other protein (Russo et al., 1999), but clinical reports have shown that Kell protein expression and Kell antigen presentation are significantly diminished...

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PMC11604768

Differential promoter activities relative to vehicle-treated cells transfected with the library were determined using MPRAnalyze.

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PMC10551595

Informed Consent: All the patient parents were informed about the purposes of the study and consequently have signed their consents.

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PMC11723947

P values were calculated using multiple unpaired t-tests with Holm-Šidák correction.

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PMC8751435

Caspase‐3‐dependent pyroptosis, which is inflammation‐involved PCD and one of the downstream pathways of reactive oxygen species (ROS), is increasingly recognized as critical pathways for PCD beyond apoptosis (Wang et al., 2017).

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PMC11185260

We anticipate a similar distribution of exogenous SMARCB1 protein in the nucleus and cytosol.

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PMC9429973

Warfarin only was the preferred long-term anticoagulant (53%).

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PMC8735881

Next, the target cells (2.5 × 10 /well) were added to effector cells, spun down to maximize cell–cell contact, and cocultured for 6 h. The fusion activity between the target and effector cells was measured by quantifying the production of the reporter luciferase as described above.

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PMC11790971

Each field of view (FOV) contained 512 × 512 pixels, covering an area of 180 × 180 μm.

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PMC11343332

Gene expression analysis by real-time PCR The gene expression of apoptotic and VEGF/FGF genes was analyzed using real-time PCR.

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PMC11745823

High c‐Myc expression is closely correlated with various cancers (such as breast cancer , liver cancer and lymphoma ) because it can enhance rapid cell proliferation and impede cell apoptosis.

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PMC5673060

Phosphosites that display at least 2-times increase in PazR (red) or increase in A204 parental (blue) with p < 0.05 are indicated.

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PMC11703992

The results showed that various diseases or phenotypes were associated with the SNP, including rheumatoid arthritis and ulcerative colitis, as described in Table S3.

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PMC9429973

IGLV3-21 had also a prognostic impact on OS since M-CLL carrying the IGLV3-21 had shorter OS similar to that of U-CLL (Figure).

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PMC11412721

Means ± SEM from four independent experiments. (

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PMC3931643

A key upstream regulator of eIF4E is the serine/threonine kinase mTOR –. Elevated mTOR activity is a prominent feature of cancer cells, including hematological malignancies .

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PMC5854676

Electrostatic interactions between magnetic hybrid nano-carriers (e.g., dendrimer complexes) show morphological features that are desired in various biomedical applications, especially nucleic acid therapy.

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PMC7229095

Final overall evaluation was made with the clones obtained from CLD of CDM1 platform and CDM2 platform.

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PMC6803987

From the above, there have been a few studies on the substance’s anti-HBV activity.

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PMC9352806

E. coli HT115 (DE3) harboring empty vector L4440 or expressing double stranded RNA corresponding to hlh-30 was transferred into LA broth containing isopropyl 1-thio-β-d-galactopyranoside (IPTG, 5 mM).

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PMC11791432

Tumor-derived annexin A1 (ANXA1) has been reported to promote the differentiation of macrophages and microglia .

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PMC11075223

It is suitable for growth in slightly acidic or neutral humus soil .

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PMC11228511

In our current studies, we matched progerin levels in cultured SMCs to levels in the aortas of Lmna mice.

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PMC9429973

Multivariate analyses of other subgroups were not performed due to the low patient number with BCL2-R/MYC-R/BCL6-R. While patients with DEL treated with Pola-R-CHP had improved PFS vs patients treated with R-CHOP (HR 0.64, 95% CI 0.42–0.97), the prognostic impact of DEL vs non-DEL was identified in the R-CHOP arm (univ...

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PMC10419319

Small molecules derived from natural products can exhibit various pharmacological properties, including anticancer activities .

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PMC10818573

However, this reaction system did not amplify the target bands (Figure 2C).

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PMC11705067

In the present study, we investigated the sensitivity of ccRCC to cuproptosis and applied comprehensive bioinformatics analysis to reveal the roles of cuproptosis-related genes FDX1 and DLAT in ccRCC.

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PMC11297139

Scale bar: 5 μm.

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PMC11577421

Second, the glycocalyx undergoes reorganization in response to shear flow, a condition encountered in vivo.

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PMC7602170

Glycogen synthase kinase 3 (GSK3) can phosphorylate and activate TSC2, thereby inhibiting mTORC1 signal.

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PMC9429973

I. Urbino, E. Lengline, M. Cerrano, F. Rabian, R. Kim, M. Sebert, R. Itzykson, E. Audisio, L. Ades, H. Dombret, E. Raffoux, D. Ferrero, E. Clappier, N. Boissel Hematology Department, AOU Città della Salute e della Scienza di Torino, Torino, Italy; Hematology Department; Hematology Laboratory, Saint-Louis Hospital - Uni...

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PMC10723784

Further studies are required to investigate whether these results are translatable in the clinic.

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PMC11279598

While Manuka honey shares constituents (such as glucose oxidases) with other types of honey, it also contains other specific phytochemical factors that potentiate its biological activity, such as methylglyoxal .

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PMC11640555

As previously mentioned, CK2 promotes GBM cell adhesion, migration, and proliferation, through the activation of several signaling pathways (NF-κB, JAK/STAT, and PI3K/Akt).

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PMC6771295

The existence of differential micro-environmental conditions in osteosarcoma vs. mesothelioma cells that diversely affect the sirtuin family members mediated autophagy could be a potential explanation for these results.

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PMC11087055

K-L’’’) Vorticity plots, displaying an averaged measure of the local rotation during each time period.

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PMC11116779

The medium was replaced every 2 days.

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PMC11781181

In various diseases, enhanced exosome production in patients is closely associated with the disruption of cell death 31-34.

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PMC11770199

Curves of tumor growth of colon cancer with the treatment of normal saline (NS), mMSCs-GFP, and mMSCs-p14.

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PMC11286266

ATF6α nuclear translocation live cell microscopy assay showing unstressed 2K parental cells and a 2K-CRT∆ clone.

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PMC10047551

The cell culture medium was replaced with a fresh medium containing AZA every day.

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PMC10213179

Fluorescence microscopy: functionalization of the aptamer sequence with a Cy5 moiety was used to check for its localization within cells using a confocal microscope.

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PMC8633974

Pearson correlation was chosen to measure whether the two variables (conservation and efficacy) were positively correlated.

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PMC11753435

There exist approximately 10 possible 20-nucleotide oligomer peptides—far too large of a space to exhaustively screen either in silico or in vitro for a given target.

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PMC10243817

Collagen expression in eosinophilic CRSwNP was negatively correlated with MEX3B but positively correlated with TGF-βR3.

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PMC11306331

Cells with a high degree of FUS condensate formation have a high CV in pixel intensity, as they harbor both bright pixels within condensates and dark pixels between them.

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PMC5600151

Second, protection of nucleic acid from nuclease is one of the major concerns in nucleic acid delivery.

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PMC10968586

In fact, treatment of colon carcinoma RKO cell line with 20–80 μM OLE diminished cell viability in a dose-dependent fashion .

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PMC11762280

AIM2 is a common sensor that initiates inflammasomes, whereas ASC, as an adapter, is involved in multiple inflammasomes such as AIM2-, NLRP3-, and NLRP12-inflammasomes .

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PMC9429973

In addition, we generated NFKBIE mice and crossed them with Em-TCL1 mice, a validated CLL mouse model, to generate immunocompetent Em-TCL1-NFKBIE.

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PMC10944868

This parameter provides insights into the energetics governing the ligand-receptor interaction.

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PMC11442172

The advent of co-culture systems has made it possible to incorporate multiple cell types to study metabolic cell-cell communication.

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PMC11257988

Molecular chaperone Hsp 90 is essential for protein stability and maturation and prevents protein degradation by the proteasome.

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PMC11730000

In this study, mTOR levels were decreased in the EGCG-administered groups.

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PMC11359735

A parallel blank lane was cut in an identical manner to use as negative controls for the experiment.

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PMC11496491

Red dots indicate up-regulated genes, green dots indicate down-regulated genes, and black dots indicate non-significant differentially expressed genes. (

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PMC11705067

All antibodies were purchased from Abcam.

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