OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC9429973	No differences were observed when comparing ALL and AML at either pocket 4 of HLA-DQB1 allele or pocket 9 of HLA-DRB1 allele.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "differ...
PMC11720808	Endogenous TLR4 proteins were immunoprecipitated from either SCU- or DMSO-treated 143B cells. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "Endogenous", "TLR4", "proteins", "were", "immunoprecipitated", "from", "...
PMC11746942	G Representative immunofluorescence images of K17 (red) and P-STAT3 (green) in psoriatic lesions from WT and S1PR3-KO mice with and without IMQ treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11247842	5Enrichment analysis.	[ { "tags": [ "O", "O", "O" ], "tokens": [ "5Enrichment", "analysis", "." ] } ]
PMC9429973	The role of DLI as a pre-emptive treatment to prevent relapse is still debated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "role", "of", "DLI", "as", "a", "pre-emptive", "treatment"...
PMC11271278	Among our analyzed cell lines, the colorectal cancer cell line COLO320DM and the gastric adenocarcinoma cell line SNU16 are known to contain ecDNAs amplifying the MYC oncogene.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "...
PMC8839885	Altered expression levels of genes involved in the uptake and efflux of platinum compounds are implicated in platinum drug resistance in cancer cells and in cancer patients .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11300639	There are several limitations to this study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "are", "several", "limitations", "to", "this", "study", "." ] } ]
PMC11618052	The EGFR-TK assay was employed to evaluate the inhibitory efficacy of the most potent antiproliferative derivatives 8f, 8g, 8h, 8j, and 8l against EGFR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11489351	We found that low pHi (EIPA) produced 8660 significantly altered transcripts (4340 upregulated, 4320 downregulated) while high pHi (NH4Cl) produced 3529 significantly altered transcripts (1891 upregulated, 1638 downregulated) compared to control MCF10A (Fig. 2C and Table S2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10887351	Recently, Dal Monte et al. have proposed a role for β3-ARs in melanoma tumor .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Recently", ",", "Dal", "Monte", "et", "al.", "have", ...
PMC11589157	De novo assembly of PacBio HiFi reads (CCS mode) was performed using HiFiasm (version 0.16.1) to generate contigs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "De", "novo",...
PMC8389560	It is known that Bcl-2 family proteins play a major role in controlling the permeabilization of the mitochondrial outer membrane during apoptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", ...
PMC11566417	The above findings propose the immortalized MDEC secretome as a strong candidate for the development of novel therapeutic applications, for example based on the potential to modulate the innate immune response in cases of acute bacterial infections, which is currently not addressed with conventional antibiotic treatmen...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	In a pivotal Phase II study (NCT02500407), mosunetuzumab induced deep and durable remissions and had a favorable safety profile in patients (pts) with relapsed/refractory (R/R) follicular lymphoma (FL) and ≥2 prior therapies (Budde et al. ASH 2021).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11335267	Fig. 4Decreased muscle volume and presence of motor dysfunction in Alx3-deficient mice A) Muscle volume relative to body weight calculated from coronal or axial images generated by MRI from hind limbs of wild type or Alx3-ko mice (n = 7–9 mice per genotype).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11583690	The obtained nitrogen adsorption-desorption isotherms were also used to evaluate nanoparticle porosity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "obtained", "nitrogen", "adsorption-desorption", "isotherms", "were", "also", "u...
PMC6901583	Thus, these results suggest that BRD4 plays a key role in migration and invasion in GIST.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", "these", "results", "suggest", ...
PMC11568601	To maintain ER homeostasis, three principal signaling pathways have been identified to trigger the unfolded protein response (UPR), including the inositol-requiring enzyme 1α (IRE1α, referred to as IRE1 hereafter), the protein kinase RNA-like ER kinase (PERK) and the activating transcription factor 6 (ATF6)-mediated si...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3888431	In the second step, the ESTScan results were screened for redundant sequences with cd-hit-est version 4.5.6 .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "second", "step", ",", "the", ...
PMC11502443	Comparison of the ability of each of the peptides to induce signaling for different pathways at the E354Q GIP receptor. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Comparison", "of", ...
PMC11763111	In contrast, the 4KO-LLT1 CAR-T cell group exhibited the longest remission period among all groups (Fig. 3F and S3G).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC7602170	It has important effects on the basic intracellular functions of cell growth, apoptosis, translation, and cell metabolism .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "has", "important", ...
PMC6892818	e ACHN, 786-O and A-704 cells were treated with mCD40L for the indicated time periods (1.5, 3 and 6 h) and expression of phospho-p40phox, phospho-ASK1 and Trx-1 was detected in controls (‘C’) vs. mCD40L-treated cells (‘mL’) by immunoblotting (40 µg protein/lane).	[ { "tags": [ "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC11697703	ChIP using anti-HA antibody or non-specific IgG was performed in purified corticospinal and callosal neurons followed by qPCR as described in.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ChIP", "using", "...
PMC11434983	Clonogenic assay (Colony formation assay): The drug–ionizing radiation interaction was tested by investigating the ability of a single cell to grow into a colony .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10877303	Later, after the protein and ligand preparation, a molecular docking approach was executed to assess the systematic binding affinity, along with the interaction mode between the MERS 3CL protease and enlisted phytochemicals for prompt recognition of potential inhibitors within a short period.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Results: A total of 191 patients were analyzed, among them 144 PMF (63 early, 81 overt fibrotic) and 47 SMF (27 post PV; 20 post ET).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7090062	Evaluation of the basal expression of beclin-1 in GIST-882 and GIST-T1 cell lines showed that higher beclin-1 levels in GIST-882 cells than those in GIST-T1 cells (Fig. 6c), which might be related to the higher tolerance of GIST-882 cells to IM treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "B-...
PMC11585565	The fluorescent signal was captured every 20 s under control of the ZEN software (ZEISS).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "fluorescent", "signal", "was", "captured",...
PMC11518994	Two are the main questions arising from these evidences.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Two", "are", "the", "main", "questions", "arising", "from", "these", "evidences", "." ] } ]
PMC8009078	The maximum number of stereoisomer generation was allowed to 32 at a pH of 7.0 ± 2.0.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "maximum", "number", "of", "stereoisomer", ...
PMC11487720	Confocal microscopy shows downregulation of α-tubulin (bottom panel; magnification: 1000X) (C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Confocal", "microscopy", "shows", "downregulation", ...
PMC9429973	DLBCLs are clinically, molecularly and genetically heterogeneous, suggesting different oncogenic mechanisms.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "DLBCLs", "are", "clinically", ",", "molecularly", "and", "genetically", "he...
PMC9844987	Our results (Figure 4) indicate that a flexible TSS architecture within a promoter may provide such a mechanism and thereby mask the effects genetic variants may have on individual decomposed promoters.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11244823	In contrast, seropositivity against gG1 was rather rare (35% Swiss sera; 14% Icelandic sera).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "contrast", ",", ...
PMC10178190	We monitored the ability of CM derived from adipocyte cells to affect platinum chemoresistance in OC cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "monitored", "the", "ability", "of", "...
PMC10854447	Anal.	[ { "tags": [ "O", "O" ], "tokens": [ "Anal", "." ] } ]
PMC11513571	Moreover, it is crucial to study cytokines and chemokines derived from airway epithelial cells (AECs), which can induce B cell responses and antibody production, especially following pulmonary infection, as we recently reported.26 TSLP cytokines are produced mainly by AECs, as well as other immune cells and tissues, an...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6114978	Analysis included 259 sarcomas.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Analysis", "included", "259", "sarcomas", "." ] } ]
PMC10938336	In summary, our novel findings provide valuable insights into the potential of these compounds to serve as novel anticancer therapeutic agents, warranting further mechanistic studies and clinical exploration.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Hematopoietic stem cell transplantation (HSCT) is one of the important means for the treatment of aplastic anemia, multiple myeloma, leukemia, lymphoma, myelodysplastic syndrome, autoimmune diseases and other hematological diseases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10976516	NCT05076760Combination of oncolytic Onc.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "NCT05076760Combination", "of", "oncolytic", "Onc", "." ] } ]
PMC9429973	Image: Summary/Conclusion: Excluding BL, most patients with MYC-IGH rearrangement had diffuse large B-cell histology (93.8%) and were classified as DH/THL (82.3%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: We wanted to evaluate the difference in viability results with folw cytometry and trypan blue exclusion with different degree of cell packing.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9672323	Cell cycle phase distribution was investigated using flow cytometry.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "cycle", "phase", "distribution", "was", "investigated", "using", "flow", "cytometry", "." ] }...
PMC11756937	This shift minimises the risk of genomic alterations, enhancing the safety and reliability of hiPSCs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "shift", "minimises", "the", "risk", "of", ...
PMC9046263	To assess differential methylation sites, we fit the model using Bayesian estimators and mapped the differentially methylated sites against the Illumina Human Methylation 450 K annotation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11206502	Amplifications of target genes BECN1 (beclin 1), P62/SQSTM (sequestosome 1), BCL-2 (B-cell lymphoma 2), and DRAM1 (Damage-Regulated Autophagy Modulator 1) in replicates were performed using ABI 7300 real-time PCR (Applied Biosystems, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11706776	Our work has identified a major role for KCNN1 in the regulation of a key function in tumor development, cell proliferation, and has suggested the role of SK1 in modulating calcium fluxes through its hyperpolarizing effect on the plasma membrane.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7582629	First, the individual single cell lipid droplets were quantified, and the result showed a 4-fold increase in lipid droplets in the MDA-MB-231 cells than normal, and 2-fold higher than that of MCF7 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", ...
PMC11768281	Understanding the secondary suppression role of PMN-MDSC suggests their potential as a target in malaria immunotherapy to prevent Treg-mediated suppression of T-cell activation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Underst...
PMC9429973	Primary endpoints were incidence of Grade 3 to 5 toxicity occurring within 60 days of AUTO4 infusion and the frequency of dose limiting toxicities within 28 days of AUTO4 infusion (DLT period).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11095939	not significant by Student’s t-test. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "not", "significant", "by", "Student", "’s", "t-test", ".", "(" ] } ]
PMC10847511	In this study, we comprehensively analyzed molecular profiles and drug screening data from the Cancer Cell Line Encyclopedia.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O" ], "tokens": [ "In", "this", ...
PMC6160470	DAC-2Amide was the most effective and already at 1.5 µM sensitized cells towards PTX to a similar extent as 10 µM verapamil.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "DAC-2Amide", ...
PMC5854676	Figure 3(d) shows an SEM image of the MgO NFKs with 200–500 nm length, where the scale bar is 1 µm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Figure"...
PMC11634027	Several proteins that act within Ds-Fat signaling have been identified.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Several", "proteins", "that", "act", "within", "Ds-Fat", "signaling", "have", "been", "identifie...
PMC11286266	Representative immunoblots from two independent experiments show the expression levels of endogenous KDEL (Lys-Asp-Glu-Leu) receptors in cell lysates from plain CHO-K1 cells, XC45-6S dual unfolded protein response (UPR) reporter cells and a derivative CRTΔ clone (2P).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "B-CellLin...
PMC4355729	The increased understanding of RCC biological pathways has led to the development of molecularly targeted therapeutic agents that have improved patient outcomes1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "incre...
PMC9031474	Despite the broad clinical use of chemotherapeutics, there are several drawbacks such as severe side effects due to the lack of selectivity or development of drug resistance .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7553912	P < 0.05 compared with WT mice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P", "<", "0.05", "compared", "with", "WT", "mice", "." ] } ]
PMC11593084	This study developed a novel CasMab against PDPN (PMab-117) by immunizing LN229/PDPN with a rat (Figure 1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "study", "...
PMC11402217	Data was analyzed by one-way ANOVA followed by Tukey’s multiple comparisons test.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "was", "analyzed", "by", "one-way", "ANOVA", "followed", "by", ...
PMC11541241	In S. cerevisiae, TIP41 interacts with and inhibits TAP42, which activates PPE1 and dampens the TOR pathway (Jacinto et al., 2001), whereas MoTIP41 could not interact with MoTAP42, indicating that the function of components of the TOR signalling pathway may be diverse in different species.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9516401	Type 2 diabetes mellitus (T2DM) is a condition characterized by insufficient insulin production or insulin resistance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Type", "2", "diabetes", "mellitus", "(...
PMC7342409	Secondary resistance to imatinib is a well-described problem in GIST occurring with tumor progression after an initial period of stabilization or response to imatinib.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC6222635	We also speculated that the anti-tumor activities may be related to the furan configuration.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "also", "speculated", "that", "the", "anti-tumor", "activities", ...
PMC11615743	Although there are limitations in identifying L‐DNA aptamers that target cell surface proteins, we successfully performed AND logical analysis of two and three membrane proteins in living cells using D‐DNA aptamers and L‐DNA logic devices.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Image: Summary/Conclusion: Our results demonstrate the value of oxygen gradient ektacytometry to the characterization of SCD patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Image", ":", "Summary/Conclusion", ...
PMC11718274	Cell viability and apoptosis induction were assessed using the Sulforhodamine B and chromatin diffusion assay, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "viability", "and", "apoptosis", "inductio...
PMC11742290	Overexpression of LGR5 could augment CRC cell adhesion .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Overexpression", "of", "LGR5", "could", "augment", "CRC", "cell", "adhesion", "." ] } ]
PMC9429973	Summary/Conclusion: The hypoxia can up-regulate the expression of CD47 in acute myeloid leukemia cells, which may be related to HIF-1α.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Summary/Conclusion...
PMC11365427	Lipofectamine 3000 (Thermo Fisher Scientific) was used to transfect the plasmids according to the manufacturer's instructions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lipofectamine", "3000", "(", "The...
PMC11759543	According to the results of the combination analysis, we use the combined treatment of 5637 cells with 0.7 μM doxorubicin and 0.6 μM vorinostat, and BFTC 905 cells with 0.95 μM doxorubicin and 2 μM vorinostat (Fig. 1F).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: Therefore, we developed and fully validated a clinical gene expression profiling assay in the Molecular Diagnostics Arizona Laboratory (MDAZL) using the Lymph3Cx gene expression signature to distinguish these lymphomas using formalin-fixed paraffin-embedded (FFPE) tissue specimens.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11139449	After 24 hours, the cells adhered to the surface, and then they were treated with different concentrations of NaBu (2.5, 5, 10, 25, 50, and 100 mM).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11476222	The MS trace of each ion chromatogram corresponding to each m/z of GD1 is shown in Figure 4C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "MS", "trace", "of", "each", ...
PMC5363531	PEM and dasatinib efficacy was established in all three MPM cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PEM", "and", "dasatinib", "efficacy", "was", "established", "in", "all", "three"...
PMC9844987	DeepLIFT relies on backpropagation of the contributions of all neurons in the neural network to the input features, nucleotides, and was used to estimate the importance of each position and nucleotide in the input sequences to predict high and low variability.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4395774	This study demonstrates the potential of hematopoietic stem cell gene therapy as a curative treatment for perforin-deficient FHL.Hemophagocytic lymphohistiocytosis (HLH) represents a spectrum of inherited and acquired conditions characterized by severe immune dysregulation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11763111	The proportion of CAR-T cells killed by the primed PBMCs was determined by bead counting.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "proportion", "of", "CAR-T", "cells", "killed", "by",...
PMC11560255	The phytochemicals found in the pine plants, including polyphenols, flavonoids, alkaloids, triterpenes, triterpenoids, sterols, glycosides, lignans, and saponins, have been demonstrated to be responsible for the medicinal properties of the plant (Sudjarwo et al., 2018).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10723784	Another limitation is that the non‐cancer cells are not tissue matched, nevertheless the results provided some indication of selectivity prior to any possible progression towards in vivo studies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11697703	The ratio of firefly to renilla fluorescence was calculated for each well.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "ratio", "of", "firefly", "to", "renilla", "fluorescence", "was", "calcula...
PMC11727306	Galactose is one of the precursors used to build glycans.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Galactose", "is", "one", "of", "the", "precursors", "used", "to", "build", "glycans", "." ...
PMC10729469	To generate TCRAβ-Tregs, a plasmid construct encoding the TCRAβ previously identified by our laboratory from Aβ-reactive Teff monoclones was electroporated into TCR-Tregs at either 0.5 μL or 0.25 μL of 1.56 μg/μL of the plasmid construct.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9412887	Yin et al. designed a dual-targeting drug delivery system (T12/P-Lipo) modified with T12 peptide and anti-PD-L1 nanobody for synergistic delivery of simvastatin/gefitinib to surmount the two huge obstacles in the treatment of NSCLC—drug resistance and brain metastases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10443665	Recently they have been widely investigated, in terms of their wide broad properties and biological activities such as immunopotentiation, reduction of the adverse effects of chemotherapy, hepatoprotection, anti-inflammation, antioxidant, and antitumor.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11335267	We found that the uptake of F-FDG was significantly reduced in the hypothalamus of Alx3-deficient mice, but not in any other cerebral region tested (Fig. 7A and B), suggesting that Alx3 is important for hypothalamic function.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11011837	At the level of polar metabolites, statistical and pathway analyses were performed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "the", "level", "of", "polar", "metabolites", ",", "statistical", ...
PMC11666785	Scale bar = 1μm.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", "=", "1μm", "." ] } ]
PMC9100622	For the EdU pulse–chase, cells were pulsed with EdU (10 µM) for 30 min, washed, and released in fresh media.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	All patients had a deep molecular response at the time of the repeat semen analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "patients", "had", "a", "deep", "molecular", "respons...
PMC11266100	In summary it has been demonstrated that the properties of the electroporation buffer, such as ionic composition, used during EP treatment, have a significant impact on gene electrotransfer efficiency.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11777207	Similarly, we observed fewer FITC cDC1s (Fig. 2, B to D) and cDC2s (Fig. 2, B, E, and F) in the dLN by number and frequency, and both FITC cDC1s and cDC2s had decreased PD-L1 expression, by geometric mean fluorescence intensity (gMFI), when compared to isotype-treated mice (fig. S2, C to H).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11588085	In OVCAR3-KRAB cells with XIST KD, the expression of XIST remained low under hypoxia, as demonstrated by RNA-seq analysis (Fig. 5 B and C).	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5035325	A weak to strong intensity staining following a homogeneous cell membrane pattern in 68 of the 92 (74 %) of EGFR was detected.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11745600	Eighteen founders were born, with 3 mice harboring the C96Y mutation in the Ins1 gene, 2 mice carrying the C96Y mutation in the Ins2 gene, and 1 mouse exhibiting the C96Y mutation in both genes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8097906	Mean ± SD, n = 3, * P < 0.001, P < 0.01, * P < 0.05, significantly different compared to vehicle control, unpaired t-test.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

No differences were observed when comparing ALL and AML at either pocket 4 of HLA-DQB1 allele or pocket 9 of HLA-DRB1 allele.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "differ...

PMC11720808

Endogenous TLR4 proteins were immunoprecipitated from either SCU- or DMSO-treated 143B cells. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "Endogenous", "TLR4", "proteins", "were", "immunoprecipitated", "from", "...

PMC11746942

G Representative immunofluorescence images of K17 (red) and P-STAT3 (green) in psoriatic lesions from WT and S1PR3-KO mice with and without IMQ treatment.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11247842

5Enrichment analysis.

[ { "tags": [ "O", "O", "O" ], "tokens": [ "5Enrichment", "analysis", "." ] } ]

PMC9429973

The role of DLI as a pre-emptive treatment to prevent relapse is still debated.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "role", "of", "DLI", "as", "a", "pre-emptive", "treatment"...

PMC11271278

Among our analyzed cell lines, the colorectal cancer cell line COLO320DM and the gastric adenocarcinoma cell line SNU16 are known to contain ecDNAs amplifying the MYC oncogene.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "...

PMC8839885

Altered expression levels of genes involved in the uptake and efflux of platinum compounds are implicated in platinum drug resistance in cancer cells and in cancer patients .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11300639

There are several limitations to this study.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "are", "several", "limitations", "to", "this", "study", "." ] } ]

PMC11618052

The EGFR-TK assay was employed to evaluate the inhibitory efficacy of the most potent antiproliferative derivatives 8f, 8g, 8h, 8j, and 8l against EGFR.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11489351

We found that low pHi (EIPA) produced 8660 significantly altered transcripts (4340 upregulated, 4320 downregulated) while high pHi (NH4Cl) produced 3529 significantly altered transcripts (1891 upregulated, 1638 downregulated) compared to control MCF10A (Fig. 2C and Table S2).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10887351

Recently, Dal Monte et al. have proposed a role for β3-ARs in melanoma tumor .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Recently", ",", "Dal", "Monte", "et", "al.", "have", ...

PMC11589157

De novo assembly of PacBio HiFi reads (CCS mode) was performed using HiFiasm (version 0.16.1) to generate contigs.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "De", "novo",...

PMC8389560

It is known that Bcl-2 family proteins play a major role in controlling the permeabilization of the mitochondrial outer membrane during apoptosis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", ...

PMC11566417

The above findings propose the immortalized MDEC secretome as a strong candidate for the development of novel therapeutic applications, for example based on the potential to modulate the innate immune response in cases of acute bacterial infections, which is currently not addressed with conventional antibiotic treatmen...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

In a pivotal Phase II study (NCT02500407), mosunetuzumab induced deep and durable remissions and had a favorable safety profile in patients (pts) with relapsed/refractory (R/R) follicular lymphoma (FL) and ≥2 prior therapies (Budde et al. ASH 2021).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11335267

Fig. 4Decreased muscle volume and presence of motor dysfunction in Alx3-deficient mice A) Muscle volume relative to body weight calculated from coronal or axial images generated by MRI from hind limbs of wild type or Alx3-ko mice (n = 7–9 mice per genotype).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11583690

The obtained nitrogen adsorption-desorption isotherms were also used to evaluate nanoparticle porosity.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "obtained", "nitrogen", "adsorption-desorption", "isotherms", "were", "also", "u...

PMC6901583

Thus, these results suggest that BRD4 plays a key role in migration and invasion in GIST.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", "these", "results", "suggest", ...

PMC11568601

To maintain ER homeostasis, three principal signaling pathways have been identified to trigger the unfolded protein response (UPR), including the inositol-requiring enzyme 1α (IRE1α, referred to as IRE1 hereafter), the protein kinase RNA-like ER kinase (PERK) and the activating transcription factor 6 (ATF6)-mediated si...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC3888431

In the second step, the ESTScan results were screened for redundant sequences with cd-hit-est version 4.5.6 .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "second", "step", ",", "the", ...

PMC11502443

Comparison of the ability of each of the peptides to induce signaling for different pathways at the E354Q GIP receptor. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Comparison", "of", ...

PMC11763111

In contrast, the 4KO-LLT1 CAR-T cell group exhibited the longest remission period among all groups (Fig. 3F and S3G).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...

PMC7602170

It has important effects on the basic intracellular functions of cell growth, apoptosis, translation, and cell metabolism .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "has", "important", ...

PMC6892818

e ACHN, 786-O and A-704 cells were treated with mCD40L for the indicated time periods (1.5, 3 and 6 h) and expression of phospho-p40phox, phospho-ASK1 and Trx-1 was detected in controls (‘C’) vs. mCD40L-treated cells (‘mL’) by immunoblotting (40 µg protein/lane).

[ { "tags": [ "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...

PMC11697703

ChIP using anti-HA antibody or non-specific IgG was performed in purified corticospinal and callosal neurons followed by qPCR as described in.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ChIP", "using", "...

PMC11434983

Clonogenic assay (Colony formation assay): The drug–ionizing radiation interaction was tested by investigating the ability of a single cell to grow into a colony .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10877303

Later, after the protein and ligand preparation, a molecular docking approach was executed to assess the systematic binding affinity, along with the interaction mode between the MERS 3CL protease and enlisted phytochemicals for prompt recognition of potential inhibitors within a short period.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Results: A total of 191 patients were analyzed, among them 144 PMF (63 early, 81 overt fibrotic) and 47 SMF (27 post PV; 20 post ET).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7090062

Evaluation of the basal expression of beclin-1 in GIST-882 and GIST-T1 cell lines showed that higher beclin-1 levels in GIST-882 cells than those in GIST-T1 cells (Fig. 6c), which might be related to the higher tolerance of GIST-882 cells to IM treatment.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "B-...

PMC11585565

The fluorescent signal was captured every 20 s under control of the ZEN software (ZEISS).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "fluorescent", "signal", "was", "captured",...

PMC11518994

Two are the main questions arising from these evidences.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Two", "are", "the", "main", "questions", "arising", "from", "these", "evidences", "." ] } ]

PMC8009078

The maximum number of stereoisomer generation was allowed to 32 at a pH of 7.0 ± 2.0.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "maximum", "number", "of", "stereoisomer", ...

PMC11487720

Confocal microscopy shows downregulation of α-tubulin (bottom panel; magnification: 1000X) (C).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Confocal", "microscopy", "shows", "downregulation", ...

PMC9429973

DLBCLs are clinically, molecularly and genetically heterogeneous, suggesting different oncogenic mechanisms.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "DLBCLs", "are", "clinically", ",", "molecularly", "and", "genetically", "he...

PMC9844987

Our results (Figure 4) indicate that a flexible TSS architecture within a promoter may provide such a mechanism and thereby mask the effects genetic variants may have on individual decomposed promoters.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11244823

In contrast, seropositivity against gG1 was rather rare (35% Swiss sera; 14% Icelandic sera).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "contrast", ",", ...

PMC10178190

We monitored the ability of CM derived from adipocyte cells to affect platinum chemoresistance in OC cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "monitored", "the", "ability", "of", "...

PMC10854447

Anal.

[ { "tags": [ "O", "O" ], "tokens": [ "Anal", "." ] } ]

PMC11513571

Moreover, it is crucial to study cytokines and chemokines derived from airway epithelial cells (AECs), which can induce B cell responses and antibody production, especially following pulmonary infection, as we recently reported.26 TSLP cytokines are produced mainly by AECs, as well as other immune cells and tissues, an...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC6114978

Analysis included 259 sarcomas.

[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Analysis", "included", "259", "sarcomas", "." ] } ]

PMC10938336

In summary, our novel findings provide valuable insights into the potential of these compounds to serve as novel anticancer therapeutic agents, warranting further mechanistic studies and clinical exploration.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Hematopoietic stem cell transplantation (HSCT) is one of the important means for the treatment of aplastic anemia, multiple myeloma, leukemia, lymphoma, myelodysplastic syndrome, autoimmune diseases and other hematological diseases.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10976516

NCT05076760Combination of oncolytic Onc.

[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "NCT05076760Combination", "of", "oncolytic", "Onc", "." ] } ]

PMC9429973

Image: Summary/Conclusion: Excluding BL, most patients with MYC-IGH rearrangement had diffuse large B-cell histology (93.8%) and were classified as DH/THL (82.3%).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Aims: We wanted to evaluate the difference in viability results with folw cytometry and trypan blue exclusion with different degree of cell packing.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC9672323

Cell cycle phase distribution was investigated using flow cytometry.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "cycle", "phase", "distribution", "was", "investigated", "using", "flow", "cytometry", "." ] }...

PMC11756937

This shift minimises the risk of genomic alterations, enhancing the safety and reliability of hiPSCs.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "shift", "minimises", "the", "risk", "of", ...

PMC9046263

To assess differential methylation sites, we fit the model using Bayesian estimators and mapped the differentially methylated sites against the Illumina Human Methylation 450 K annotation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11206502

Amplifications of target genes BECN1 (beclin 1), P62/SQSTM (sequestosome 1), BCL-2 (B-cell lymphoma 2), and DRAM1 (Damage-Regulated Autophagy Modulator 1) in replicates were performed using ABI 7300 real-time PCR (Applied Biosystems, USA).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11706776

Our work has identified a major role for KCNN1 in the regulation of a key function in tumor development, cell proliferation, and has suggested the role of SK1 in modulating calcium fluxes through its hyperpolarizing effect on the plasma membrane.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7582629

First, the individual single cell lipid droplets were quantified, and the result showed a 4-fold increase in lipid droplets in the MDA-MB-231 cells than normal, and 2-fold higher than that of MCF7 cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", ...

PMC11768281

Understanding the secondary suppression role of PMN-MDSC suggests their potential as a target in malaria immunotherapy to prevent Treg-mediated suppression of T-cell activation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Underst...

PMC9429973

Primary endpoints were incidence of Grade 3 to 5 toxicity occurring within 60 days of AUTO4 infusion and the frequency of dose limiting toxicities within 28 days of AUTO4 infusion (DLT period).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11095939

not significant by Student’s t-test. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "not", "significant", "by", "Student", "’s", "t-test", ".", "(" ] } ]

PMC10847511

In this study, we comprehensively analyzed molecular profiles and drug screening data from the Cancer Cell Line Encyclopedia.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O" ], "tokens": [ "In", "this", ...

PMC6160470

DAC-2Amide was the most effective and already at 1.5 µM sensitized cells towards PTX to a similar extent as 10 µM verapamil.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "DAC-2Amide", ...

PMC5854676

Figure 3(d) shows an SEM image of the MgO NFKs with 200–500 nm length, where the scale bar is 1 µm.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Figure"...

PMC11634027

Several proteins that act within Ds-Fat signaling have been identified.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Several", "proteins", "that", "act", "within", "Ds-Fat", "signaling", "have", "been", "identifie...

PMC11286266

Representative immunoblots from two independent experiments show the expression levels of endogenous KDEL (Lys-Asp-Glu-Leu) receptors in cell lysates from plain CHO-K1 cells, XC45-6S dual unfolded protein response (UPR) reporter cells and a derivative CRTΔ clone (2P).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "B-CellLin...

PMC4355729

The increased understanding of RCC biological pathways has led to the development of molecularly targeted therapeutic agents that have improved patient outcomes1.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "incre...

PMC9031474

Despite the broad clinical use of chemotherapeutics, there are several drawbacks such as severe side effects due to the lack of selectivity or development of drug resistance .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7553912

P < 0.05 compared with WT mice.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P", "<", "0.05", "compared", "with", "WT", "mice", "." ] } ]

PMC11593084

This study developed a novel CasMab against PDPN (PMab-117) by immunizing LN229/PDPN with a rat (Figure 1).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "study", "...

PMC11402217

Data was analyzed by one-way ANOVA followed by Tukey’s multiple comparisons test.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "was", "analyzed", "by", "one-way", "ANOVA", "followed", "by", ...

PMC11541241

In S. cerevisiae, TIP41 interacts with and inhibits TAP42, which activates PPE1 and dampens the TOR pathway (Jacinto et al., 2001), whereas MoTIP41 could not interact with MoTAP42, indicating that the function of components of the TOR signalling pathway may be diverse in different species.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9516401

Type 2 diabetes mellitus (T2DM) is a condition characterized by insufficient insulin production or insulin resistance.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Type", "2", "diabetes", "mellitus", "(...

PMC7342409

Secondary resistance to imatinib is a well-described problem in GIST occurring with tumor progression after an initial period of stabilization or response to imatinib.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC6222635

We also speculated that the anti-tumor activities may be related to the furan configuration.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "also", "speculated", "that", "the", "anti-tumor", "activities", ...

PMC11615743

Although there are limitations in identifying L‐DNA aptamers that target cell surface proteins, we successfully performed AND logical analysis of two and three membrane proteins in living cells using D‐DNA aptamers and L‐DNA logic devices.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Image: Summary/Conclusion: Our results demonstrate the value of oxygen gradient ektacytometry to the characterization of SCD patients.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Image", ":", "Summary/Conclusion", ...

PMC11718274

Cell viability and apoptosis induction were assessed using the Sulforhodamine B and chromatin diffusion assay, respectively.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "viability", "and", "apoptosis", "inductio...

PMC11742290

Overexpression of LGR5 could augment CRC cell adhesion .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Overexpression", "of", "LGR5", "could", "augment", "CRC", "cell", "adhesion", "." ] } ]

PMC9429973

Summary/Conclusion: The hypoxia can up-regulate the expression of CD47 in acute myeloid leukemia cells, which may be related to HIF-1α.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Summary/Conclusion...

PMC11365427

Lipofectamine 3000 (Thermo Fisher Scientific) was used to transfect the plasmids according to the manufacturer's instructions.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lipofectamine", "3000", "(", "The...

PMC11759543

According to the results of the combination analysis, we use the combined treatment of 5637 cells with 0.7 μM doxorubicin and 0.6 μM vorinostat, and BFTC 905 cells with 0.95 μM doxorubicin and 2 μM vorinostat (Fig. 1F).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Aims: Therefore, we developed and fully validated a clinical gene expression profiling assay in the Molecular Diagnostics Arizona Laboratory (MDAZL) using the Lymph3Cx gene expression signature to distinguish these lymphomas using formalin-fixed paraffin-embedded (FFPE) tissue specimens.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11139449

After 24 hours, the cells adhered to the surface, and then they were treated with different concentrations of NaBu (2.5, 5, 10, 25, 50, and 100 mM).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11476222

The MS trace of each ion chromatogram corresponding to each m/z of GD1 is shown in Figure 4C.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "MS", "trace", "of", "each", ...

PMC5363531

PEM and dasatinib efficacy was established in all three MPM cell lines.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PEM", "and", "dasatinib", "efficacy", "was", "established", "in", "all", "three"...

PMC9844987

DeepLIFT relies on backpropagation of the contributions of all neurons in the neural network to the input features, nucleotides, and was used to estimate the importance of each position and nucleotide in the input sequences to predict high and low variability.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC4395774

This study demonstrates the potential of hematopoietic stem cell gene therapy as a curative treatment for perforin-deficient FHL.Hemophagocytic lymphohistiocytosis (HLH) represents a spectrum of inherited and acquired conditions characterized by severe immune dysregulation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11763111

The proportion of CAR-T cells killed by the primed PBMCs was determined by bead counting.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "proportion", "of", "CAR-T", "cells", "killed", "by",...

PMC11560255

The phytochemicals found in the pine plants, including polyphenols, flavonoids, alkaloids, triterpenes, triterpenoids, sterols, glycosides, lignans, and saponins, have been demonstrated to be responsible for the medicinal properties of the plant (Sudjarwo et al., 2018).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10723784

Another limitation is that the non‐cancer cells are not tissue matched, nevertheless the results provided some indication of selectivity prior to any possible progression towards in vivo studies.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11697703

The ratio of firefly to renilla fluorescence was calculated for each well.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "ratio", "of", "firefly", "to", "renilla", "fluorescence", "was", "calcula...

PMC11727306

Galactose is one of the precursors used to build glycans.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Galactose", "is", "one", "of", "the", "precursors", "used", "to", "build", "glycans", "." ...

PMC10729469

To generate TCRAβ-Tregs, a plasmid construct encoding the TCRAβ previously identified by our laboratory from Aβ-reactive Teff monoclones was electroporated into TCR-Tregs at either 0.5 μL or 0.25 μL of 1.56 μg/μL of the plasmid construct.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9412887

Yin et al. designed a dual-targeting drug delivery system (T12/P-Lipo) modified with T12 peptide and anti-PD-L1 nanobody for synergistic delivery of simvastatin/gefitinib to surmount the two huge obstacles in the treatment of NSCLC—drug resistance and brain metastases.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10443665

Recently they have been widely investigated, in terms of their wide broad properties and biological activities such as immunopotentiation, reduction of the adverse effects of chemotherapy, hepatoprotection, anti-inflammation, antioxidant, and antitumor.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11335267

We found that the uptake of F-FDG was significantly reduced in the hypothalamus of Alx3-deficient mice, but not in any other cerebral region tested (Fig. 7A and B), suggesting that Alx3 is important for hypothalamic function.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11011837

At the level of polar metabolites, statistical and pathway analyses were performed.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "the", "level", "of", "polar", "metabolites", ",", "statistical", ...

PMC11666785

Scale bar = 1μm.

[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", "=", "1μm", "." ] } ]

PMC9100622

For the EdU pulse–chase, cells were pulsed with EdU (10 µM) for 30 min, washed, and released in fresh media.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

All patients had a deep molecular response at the time of the repeat semen analysis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "patients", "had", "a", "deep", "molecular", "respons...

PMC11266100

In summary it has been demonstrated that the properties of the electroporation buffer, such as ionic composition, used during EP treatment, have a significant impact on gene electrotransfer efficiency.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11777207

Similarly, we observed fewer FITC cDC1s (Fig. 2, B to D) and cDC2s (Fig. 2, B, E, and F) in the dLN by number and frequency, and both FITC cDC1s and cDC2s had decreased PD-L1 expression, by geometric mean fluorescence intensity (gMFI), when compared to isotype-treated mice (fig. S2, C to H).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11588085

In OVCAR3-KRAB cells with XIST KD, the expression of XIST remained low under hypoxia, as demonstrated by RNA-seq analysis (Fig. 5 B and C).

[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC5035325

A weak to strong intensity staining following a homogeneous cell membrane pattern in 68 of the 92 (74 %) of EGFR was detected.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC11745600

Eighteen founders were born, with 3 mice harboring the C96Y mutation in the Ins1 gene, 2 mice carrying the C96Y mutation in the Ins2 gene, and 1 mouse exhibiting the C96Y mutation in both genes.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8097906

Mean ± SD, n = 3, *** P < 0.001, ** P < 0.01, * P < 0.05, significantly different compared to vehicle control, unpaired t-test.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...