OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC9429973	Almost half the patients were ≤6 years at time of BMT with 3/49 ≥18 years.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Almost", "half", "the", "patients", "were", "≤6", "years", ...
PMC11453018	D Quantification of intensity of Annexin V staining.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "D", "Quantification", "of", "intensity", "of", "Annexin", "V", "staining", "." ] } ]
PMC10317042	To determine whether chromatin structure was altered by vorinostat treatment, we performed a single-cell ATAC with high-throughput sequencing (scATAC-seq) in MP-CCS-SY cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ],...
PMC11488203	In extension of previous studies with an exosome mixture of taxol-treated MSC , the present work discriminated distinct anti-tumor effects of taxol-loaded exosomes isolated from four individual MSC populations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11721587	Whether biomolecular condensates can fulfill other function has remained unexplored.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Whether", "biomolecular", "condensates", "can", "fulfill", "other", "function", "has", "remained", ...
PMC9878562	Given the poor prognosis of DLBCL patients with brain infiltrations (67, 68), understanding the underlying mechanism is of great clinical relevance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	Seroconversion rates were greater in patients who never received treatment (82%), dropped considerably in those on-therapy (35%), particularly with anti-CD38 monoclonal antibodies, and bounced back once patients were off-treatment (80%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8777939	Thereafter, the cells were lightly washed with PBS twice, and the scratched cells were cultured with etravirine (0, 5, and 10 µM).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7961460	Samples were freeze-dried and then dissolved in 10 μL of 0.2% trifluoroacetic acid; 1 μL was mixed with 1 μL of a solution of alpha-cyano-4-hydroxycinammic acid, 10 mg/mL in acetonitrile, 0.2% trifluoroacetic acid 7:3 (v:v), and the mixture was applied onto the metallic sample plate and air dried.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11707832	A study by Stephanie Widdison et al. found heightened MAN2B1 expression in Mycobacterium bovis-infected bovine alveolar macrophages compared to those infected with M. tuberculosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	Main adverse events were infectious in 25% (10 cases) and hematological in 22% (9 patients).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Main", "adverse", ...
PMC10874773	According to literature review, approximately 20 monomeric compounds of this type have been isolated so far.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "According", "to", "literature", "review", ",", ...
PMC11448304	g Subcellular localization of significantly regulated proteins Proteomic data on A549 and RA549.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O" ], "tokens": [ "g", "Subcellular", "localization", "of", "significantly", "regulated"...
PMC10900886	In imDCs co-cultured with BLCL, we observed an average percentage of 10% ± 4 VP1 imDCs at 6 hpi, although this percentage decreased at 24 hpi (4% ± 2) (Fig. 5B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10734950	Typically, an apoptotic death is irreversible after caspase-3 is activated .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Typically", ",", "an", "apoptotic", "death", "is", "irreversible", "after", "caspase-3", ...
PMC11802929	b UMAP embedding of all peptides (Pep-UMAP) based on their physicochemical properties with peptide clusters colored (legend on the right), each dot represents a unique SARS-CoV-2 peptide.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11743975	Knockout of mitofusins has been shown to impair ATP biosynthesis (Seidlmayer et al., 2019).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Knockout", "of", "mitofusins", "has", "been", ...
PMC11806106	Further, it was shown that the opioids induce diverse conformations within the activated MOR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Further", ",", "it", "was", "shown", "that", "the", "...
PMC11706776	Following a shRNA-mediated silencing approach in ES cells, an approach of overexpression of EWS::FLI1 in the putative cell of origin of ES, MSCs, was used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11435360	Exogenous H2S has been shown to down-regulate active caspase-3 in human esophageal squamous cell cancer cells, suggesting that H2S exerts anti-apoptotic effects in cancer cells [Lei 2016].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11767793	We identified at least two commercial sources of these particles—Nanopartz.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "identified", "at", "least", "two", "commercial", "sources", "of", "these",...
PMC3122064	This (re)activation leads to cell-cycle arrest and or apoptosis in tumour cells with wild-type p53.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "(re)activation", "leads", "to", "cell-cycle", "arrest", ...
PMC9341513	MYEOV shows much lower expression than the other three genes (Supplemental Fig. S3A) and is covered by enhancer-associated H3K4me1 and H3K27ac states.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	No inversion or translocation were detected.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "inversion", "or", "translocation", "were", "detected", "." ] } ]
PMC7305184	This process/experiment was repeated twice for 15 generations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "process/experiment", "was", "repeated", "twice", "for", "15", "generations", "." ] } ]
PMC6222635	An amount of 30 mg PPF was weighed precisely and deuterium-exchanged by freeze drying three time from 99% D2O to obtain the sample solution.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC5874706	A427 cells were seeded at a density of 10 cells per well into 96-well plates in 100 μL of growth medium.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A427", "cells"...
PMC11699042	Combat-Seq adjusted data was used as count input for DESeqDataSet.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Combat-Seq", "adjusted", "data", "was", "used", "as", "count", "input", "for", "DESeqDataSet", ...
PMC10772747	Subsequently, the extract was dried in an oven at 40°C before being used for further analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Subsequently", ",", "the", "extra...
PMC8956657	We show that ORF4b binds to both the major and minor NLS binding sites on the IMPαs through a novel and highly unusual way that is conserved across two IMPα family members.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Median age was 68 years (range 37–79).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Median", "age", "was", "68", "years", "(", "range", "37–79", ")", "." ] } ]
PMC9398137	These data indicate that the level of expression of MCL1, but not BCL-XL impact sensitivity of DLBCL and Burkitt lymphoma cell lines to S63845.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O"...
PMC9386809	To a solution of aldehyde (1 mmol) and indole (2 mmol) dissolved in CH3CN (2 mL), 1 mol % catalyst [0.01 mmol, ≈8 mg of Cl2Ti–BPC complex, ≈8 mg of Zn–BPC complex, and ≈9 mg of Cl2Zr–BPC complex 2] was added.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Estimated DOR at 1-year was 89% (95% CI, 71-100).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Estimated", "DOR", "at", "1-year", "was", "89", ...
PMC7823217	In addition to the importance of selecting adequate bioinks and crosslinking methods for generation of viable bioprinted cancer models, the methodology of cell integration is also critical, which requires preparation of cancer and stromal bioinks separately.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11320834	Malignant ascites contribute to metastasis and therapy resistance and portend the poorest outcomes for cancer patients .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Malignant", "ascites", "contribute", "to", "metastasis", ...
PMC11481779	The full results from the analysis, with the violin plot of the correlations, as well as two examples, can be seen in Fig. 4.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8753818	In this assay each experiment was repeated 3 times and n = 3, (: > 0.05, : > 0.01, : > 0.001, **: > 0.0001) JRed expression assay; a The histogram of JRed expression in CHO-KO and CHO-K1 cells after 120 h of transfection, b the chart containing the percentage of JRed expression in CHO-KO and CHO-K1 cells after ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11045125	Three days later cells were treated with puromycin for 2 days, and then grown on or off an IL40/IL21 expressing feeder cell layer for another 2 days before harvesting protein extracts for immunoblot analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11767725	These changes exacerbate susceptibility to dermatologic conditions such as psoriasis, atopic dermatitis (AD), and chronic wounds .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "changes", "exacerba...
PMC11707577	The percentage of apoptotic, necrotic and live cells was determined at 3 and 24 h after the PDT treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "percentage", "of", ...
PMC11680049	The results indicated that the studied extracts were low in toxicity to normal FetMSC cells and HepG2 liver carcinoma cells but demonstrated high toxicity toward the immortal HeLa cervical cancer cell line and the human glioblastoma A-172 cell line.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC3931643	The classical mTOR inhibitor rapamycin functions through an allosteric mechanism .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "classical", "mTOR", "inhibitor", "rapamycin", "functions", "through", "an", "allosteric", ...
PMC9429973	All pts achieved a response within 1 cycle among which 4 pts, including one with TP53,proceeded to hematopoietic stem cell transplant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "pts",...
PMC6114978	Total protein concentration was measured using Pierce BCA™ Protein Assay Kit (ThermoFisher Scientific, Waltham, MA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Total", "protein", "concentr...
PMC11591794	It has been reported that GA exhibits anticancer properties by increasing P53 gene expression via the mitochondrial apoptotic pathway on human SCLC H446 cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "token...
PMC11322866	We observed that GSK126 treatment resulted in the “aggregation-densification” of DAPI staining under confocal microscopy, which is indicative of SAHF ( Figure 1E) and is usually associated with OIS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Patients aged ≥20 years with RRMM (including those not refractory to bortezomib (BOR), carfilzomib (CFZ), or LEN who provided written informed consent were enrolled.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11564405	These patients were identified at Shanghai Jiao Tong University School of Medicine, affiliated with Renji Hospital, spanning the period during the timeframe encompassing January 2008 through December 2013.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10926885	Our research revealed that NDE1 is strongly linked to tumour mutation burden (TMB), microsatellite instability (MSI), tumour purity and homologous recombination deficit (HRD) in a range of tumours, in addition to immune checkpoint genes in the majority of tumours.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11758416	Example for gating strategy is shown in Figure 2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Example", "for", "gating", "strategy", "is", "shown", "in", "Figure", "2", "." ] } ]
PMC11551844	The MTT colorimetric assay was used for cell viability.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "MTT", "colorimetric", "assay", "was", "used", "for", "cell", "viability", "." ] } ]
PMC11344246	An effect was also seen to a lesser extent in the JHOM-1 cell line, with RMUG-S only showing minimal reduction in cell number at the highest doses tested.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC10125312	In the case of noncancerous cell lines, no differences were found between the different conditions (CTL, ⌀AuNR, +AuNR) at any time point after treatment (Figure 5G).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11291490	Furthermore, Daniel Graf and colleagues identified a natural 18 kDa fragment in human CD40L (hCD40L) that constitutes the extracellular domain of hCD40L, termed soluble CD40L (sCD40L).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11194678	STAU1 depletion resulted in a decreased autophagosome/autolysosome ratio in STHdh cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "STAU1", "depletion", "resulted", "in", "a", "decreased", "autophagosome/autolysosome", "...
PMC9429973	Results: Results: Hard evidence on the incidence and prevalence of MM in the region is scarce, but the experts perceive an increase in MM cases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8728081	The ROS of Kajjali treated cells were found to be decreased with increasing concentration (Fig. 3b) due to cell death.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "ROS",...
PMC11680982	Protein concentration was determined by the BCA protein assay.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Protein", "concentration", "was", "determined", "by", "the", "BCA", "protein", "assay", "." ] } ]
PMC11754432	Inhibition of JAK1 reduced CCL2 expression towards basal levels in both control and ALOX15B siRNA transfected cells following treatments with either the cytokine cocktail or IFNγ alone (Fig. 3C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11438317	Next, we focused on SKAP1, a close protein to SKAP2 that presents Y232 and Y271, which align with SKAP2 Y237 and Y261, but lacks a Tyr equivalent to SKAP2 Y75.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11733919	Left: TEM micrograph of as-synthesized MNP@OA and its size distribution (13.2 ± 1.3 nm).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Left", ":", "TEM", "micrograph", "of", "as-...
PMC9275501	Cosco et al. (2015) co-encapsulated RES and 5-FU in ultra-deformable liposomes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cosco", "et", "al.", "(", "2015", ")", "co-encapsulated", "RES", "and...
PMC11777207	Furthermore, we document how the αPD-L1 antibody atezolizumab prevents DC migration of intratumorally transferred DCs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "we", "document", "how", "the", ...
PMC11745823	Consistent with previous findings, RIT1 overexpression induced p‐PI3K, p‐AKT and c‐Myc without affecting PI3K and AKT levels (Figure 5A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10728200	Inside the cell, the clearance of lipid peroxides primarily relies on the activity of the antioxidant enzyme glutathione peroxidase 4 (GPX4).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11723947	We therefore decided to exclude them before running further analyses.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "therefore", "decided", "to", "exclude", "them", "before", "running", "further", "analyses"...
PMC7868205	Biological and chemical methods build particles from the bottom-up.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Biological", "and", "chemical", "methods", "build", "particles", "from", "the", "bottom-up", "." ] } ...
PMC9895440	n = 7 donors of n = 2 experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "n", "=", "7", "donors", "of", "n", "=", "2", "experiments", "." ] } ]
PMC11742670	model MAE for the A-549 cell line. (	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ "model", "MAE", "for", "the", "A-549", "cell", "line", ".", "(" ] } ]
PMC9424261	Flow cytometry was used to detect lipid ROS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Flow", "cytometry", "was", "used", "to", "detect", "lipid", "ROS", "." ] } ]
PMC11506670	All experiments were conducted at least three times, and each trial involved at least three technical replicates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "experiments", "were", "conducted", ...
PMC11680562	The morphology of HeLa cells was examined using Giemsa staining under a bright-field microscope.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "morphology", "of", "HeLa", "cells", "was", "examined",...
PMC11471176	These results regard the new molecule LMS1007 are now under publication in a top journal in drug discovery.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "results", "regard", "the", "n...
PMC11525028	mouse models (n = 8 per group), by log-rank test in (H). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "mouse", "models", "(", "n", "=", ...
PMC11683240	For the precipitation analysis, PT (100 ng) and TcdB (50 ng) and inhibitors, α1AT and α-defensin-6 (6 μM) were incubated for 30 min in PBS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10798140	Halting of the cell cycle in the G0G1 phase was accompanied by a drop in the percentage of cells in the S phase, indicating that these chemicals can induce cell cycle arrest in the G0G1 phase.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7294030	In the worldwide, lung cancer is the most common cause of death in men more than women (Pakzad et al., 2015).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10975211	The resulting buforin conjugate presented better anticancer effects than buforin alone in the pathological-producing MMP cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "resulting", "buforin", "conjugate", "presented", ...
PMC11476222	However, ganglioside analysis is challenging due to the need for more cost-effective extraction methods and improved accuracy, as their low concentration and the presence of complex biomolecular matrices often interfere with detection and analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10706275	This is a consequence of foreign gene recombination into chromosomes by random integration.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "is", "a", "consequence", "of", "foreign", "gene", "recombination", ...
PMC11737091	However, the specific mechanisms by which DBF4 functions within the ccRCC immune microenvironment, as well as the potential therapeutic benefits of targeting DBF4 in combination with immunotherapy, require further investigation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11748335	The bamCompare program from deepTools was employed to generate BigWig files with the CPM normalization method .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "bamCompare", "program", "from", "deepTools", "w...
PMC11607321	Here, a latent representation is a learned, abstracted feature set (embeddings) within the hidden layers of the neural network that encapsulates the major information from the input data.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Summary/Conclusion: The elevated oxidative markers and reduced antioxidant support oxidative stress in patients with DLBCL, while MDA can be a prognostic marker of overall survival.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11742670	The suggested model predicts the IC50of Vidarabine against three cancer cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "suggested", "model", "predicts", "the", "IC50of", "Vidarabine", "against", ...
PMC11532793	The use of pseudo- or quasi-alignment makes kallisto and Salmon computationally faster than any splice-aware genome aligner designed for short read sequencing data while providing measurements of the relative expression of individual transcripts directly.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11641630	Our study has examined both cell migration and invasion, anchorage-independent tumor growth, and active MMP-9 production (via gelatin zymography) using BCG immunotherapy compared to another mycobacterium-based antitumor agent.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10698968	Scale bar = 100 µm.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", "=", "100", "µm", "." ] } ]
PMC9428827	injections of PBS, wtIL-2 (30,000 IU), or no-alpha mutein (300 IU) twice a day, and the cycle was repeated after one resting week.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11534377	The groups receiving treatment of 5-Aza alone or in combination with IR exhibited a significant reduction in tumor growth compared to the controls and IR only groups (Figure 12).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11222184	The results revealed that XL-888 and Debio0932 had a role in regulating many cancer-related pathways such as migration, invasion, metastasis, angiogenesis, and apoptosis in SH-SY5Y cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11659734	These differences underscore the need for developing NAMs, including 3D human tissue models.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "differences", "underscore", "the", "need", "for", "developing...
PMC9503669	Of the many known Nef functions, pharmacological suppression of Nef-mediated MHC-I downregulation may be the key to an effective CTL response and viral clearance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11673902	Advances in microfluidics will further advance the field, enabling us to realize efficient and reliable cellular mechanical measurements on a larger scale.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Advance...
PMC9429973	Twenty-seven of 49 (55%) patients with a FDG PET/CT positive result were MRD negative before KRd consolidation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Twenty-seven", "of", "49", ...
PMC8567602	Others have shown that the fusion's SSXRD domain interacts with a ubiquitin E3 ligase with otherwise established BAF-family component targeting capacity (39).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11746948	Image in b, c, d, e, g, i shows representative results from three independent experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Image", "in", "b", ","...
PMC11694625	Compared with the standard peaks of NDMA and NDEA in Fig. S19a and b,† no NDMA and NDEA were detected in 3a–3d (Fig. S19c–j†).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9454178	THZ1 cells (HY-80013A) were purchased from MedChemExpress (MCE, Monmouth Junction, NJ, USA).	[ { "tags": [ "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "THZ1", "cells", "(", ...

PMC9429973

Almost half the patients were ≤6 years at time of BMT with 3/49 ≥18 years.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Almost", "half", "the", "patients", "were", "≤6", "years", ...

PMC11453018

D Quantification of intensity of Annexin V staining.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "D", "Quantification", "of", "intensity", "of", "Annexin", "V", "staining", "." ] } ]

PMC10317042

To determine whether chromatin structure was altered by vorinostat treatment, we performed a single-cell ATAC with high-throughput sequencing (scATAC-seq) in MP-CCS-SY cells.

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PMC11488203

In extension of previous studies with an exosome mixture of taxol-treated MSC , the present work discriminated distinct anti-tumor effects of taxol-loaded exosomes isolated from four individual MSC populations.

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PMC11721587

Whether biomolecular condensates can fulfill other function has remained unexplored.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Whether", "biomolecular", "condensates", "can", "fulfill", "other", "function", "has", "remained", ...

PMC9878562

Given the poor prognosis of DLBCL patients with brain infiltrations (67, 68), understanding the underlying mechanism is of great clinical relevance.

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PMC9429973

Seroconversion rates were greater in patients who never received treatment (82%), dropped considerably in those on-therapy (35%), particularly with anti-CD38 monoclonal antibodies, and bounced back once patients were off-treatment (80%).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8777939

Thereafter, the cells were lightly washed with PBS twice, and the scratched cells were cultured with etravirine (0, 5, and 10 µM).

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PMC7961460

Samples were freeze-dried and then dissolved in 10 μL of 0.2% trifluoroacetic acid; 1 μL was mixed with 1 μL of a solution of alpha-cyano-4-hydroxycinammic acid, 10 mg/mL in acetonitrile, 0.2% trifluoroacetic acid 7:3 (v:v), and the mixture was applied onto the metallic sample plate and air dried.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11707832

A study by Stephanie Widdison et al. found heightened MAN2B1 expression in Mycobacterium bovis-infected bovine alveolar macrophages compared to those infected with M. tuberculosis.

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PMC9429973

Main adverse events were infectious in 25% (10 cases) and hematological in 22% (9 patients).

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PMC10874773

According to literature review, approximately 20 monomeric compounds of this type have been isolated so far.

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PMC11448304

g Subcellular localization of significantly regulated proteins Proteomic data on A549 and RA549.

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PMC10900886

In imDCs co-cultured with BLCL, we observed an average percentage of 10% ± 4 VP1 imDCs at 6 hpi, although this percentage decreased at 24 hpi (4% ± 2) (Fig. 5B).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10734950

Typically, an apoptotic death is irreversible after caspase-3 is activated .

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PMC11802929

b UMAP embedding of all peptides (Pep-UMAP) based on their physicochemical properties with peptide clusters colored (legend on the right), each dot represents a unique SARS-CoV-2 peptide.

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PMC11743975

Knockout of mitofusins has been shown to impair ATP biosynthesis (Seidlmayer et al., 2019).

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PMC11806106

Further, it was shown that the opioids induce diverse conformations within the activated MOR.

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PMC11706776

Following a shRNA-mediated silencing approach in ES cells, an approach of overexpression of EWS::FLI1 in the putative cell of origin of ES, MSCs, was used.

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PMC11435360

Exogenous H2S has been shown to down-regulate active caspase-3 in human esophageal squamous cell cancer cells, suggesting that H2S exerts anti-apoptotic effects in cancer cells [Lei 2016].

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11767793

We identified at least two commercial sources of these particles—Nanopartz.

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PMC3122064

This (re)activation leads to cell-cycle arrest and or apoptosis in tumour cells with wild-type p53.

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PMC9341513

MYEOV shows much lower expression than the other three genes (Supplemental Fig. S3A) and is covered by enhancer-associated H3K4me1 and H3K27ac states.

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PMC9429973

No inversion or translocation were detected.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "inversion", "or", "translocation", "were", "detected", "." ] } ]

PMC7305184

This process/experiment was repeated twice for 15 generations.

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PMC6222635

An amount of 30 mg PPF was weighed precisely and deuterium-exchanged by freeze drying three time from 99% D2O to obtain the sample solution.

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PMC5874706

A427 cells were seeded at a density of 10 cells per well into 96-well plates in 100 μL of growth medium.

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PMC11699042

Combat-Seq adjusted data was used as count input for DESeqDataSet.

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PMC10772747

Subsequently, the extract was dried in an oven at 40°C before being used for further analysis.

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PMC8956657

We show that ORF4b binds to both the major and minor NLS binding sites on the IMPαs through a novel and highly unusual way that is conserved across two IMPα family members.

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PMC9429973

Median age was 68 years (range 37–79).

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PMC9398137

These data indicate that the level of expression of MCL1, but not BCL-XL impact sensitivity of DLBCL and Burkitt lymphoma cell lines to S63845.

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PMC9386809

To a solution of aldehyde (1 mmol) and indole (2 mmol) dissolved in CH3CN (2 mL), 1 mol % catalyst [0.01 mmol, ≈8 mg of Cl2Ti–BPC complex, ≈8 mg of Zn–BPC complex, and ≈9 mg of Cl2Zr–BPC complex 2] was added.

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PMC9429973

Estimated DOR at 1-year was 89% (95% CI, 71-100).

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PMC7823217

In addition to the importance of selecting adequate bioinks and crosslinking methods for generation of viable bioprinted cancer models, the methodology of cell integration is also critical, which requires preparation of cancer and stromal bioinks separately.

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PMC11320834

Malignant ascites contribute to metastasis and therapy resistance and portend the poorest outcomes for cancer patients .

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PMC11481779

The full results from the analysis, with the violin plot of the correlations, as well as two examples, can be seen in Fig. 4.

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PMC8753818

In this assay each experiment was repeated 3 times and n = 3, (*: > 0.05, **: > 0.01, ***: > 0.001, ****: > 0.0001) JRed expression assay; a The histogram of JRed expression in CHO-KO and CHO-K1 cells after 120 h of transfection, b the chart containing the percentage of JRed expression in CHO-KO and CHO-K1 cells after ...

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PMC11045125

Three days later cells were treated with puromycin for 2 days, and then grown on or off an IL40/IL21 expressing feeder cell layer for another 2 days before harvesting protein extracts for immunoblot analysis.

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PMC11767725

These changes exacerbate susceptibility to dermatologic conditions such as psoriasis, atopic dermatitis (AD), and chronic wounds .

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PMC11707577

The percentage of apoptotic, necrotic and live cells was determined at 3 and 24 h after the PDT treatment.

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PMC11680049

The results indicated that the studied extracts were low in toxicity to normal FetMSC cells and HepG2 liver carcinoma cells but demonstrated high toxicity toward the immortal HeLa cervical cancer cell line and the human glioblastoma A-172 cell line.

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PMC3931643

The classical mTOR inhibitor rapamycin functions through an allosteric mechanism .

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PMC9429973

All pts achieved a response within 1 cycle among which 4 pts, including one with TP53,proceeded to hematopoietic stem cell transplant.

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PMC6114978

Total protein concentration was measured using Pierce BCA™ Protein Assay Kit (ThermoFisher Scientific, Waltham, MA).

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PMC11591794

It has been reported that GA exhibits anticancer properties by increasing P53 gene expression via the mitochondrial apoptotic pathway on human SCLC H446 cells .

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PMC11322866

We observed that GSK126 treatment resulted in the “aggregation-densification” of DAPI staining under confocal microscopy, which is indicative of SAHF ( Figure 1E) and is usually associated with OIS.

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PMC9429973

Patients aged ≥20 years with RRMM (including those not refractory to bortezomib (BOR), carfilzomib (CFZ), or LEN who provided written informed consent were enrolled.

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PMC11564405

These patients were identified at Shanghai Jiao Tong University School of Medicine, affiliated with Renji Hospital, spanning the period during the timeframe encompassing January 2008 through December 2013.

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PMC10926885

Our research revealed that NDE1 is strongly linked to tumour mutation burden (TMB), microsatellite instability (MSI), tumour purity and homologous recombination deficit (HRD) in a range of tumours, in addition to immune checkpoint genes in the majority of tumours.

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PMC11758416

Example for gating strategy is shown in Figure 2.

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PMC11551844

The MTT colorimetric assay was used for cell viability.

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PMC11344246

An effect was also seen to a lesser extent in the JHOM-1 cell line, with RMUG-S only showing minimal reduction in cell number at the highest doses tested.

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PMC10125312

In the case of noncancerous cell lines, no differences were found between the different conditions (CTL, ⌀AuNR, +AuNR) at any time point after treatment (Figure 5G).

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PMC11291490

Furthermore, Daniel Graf and colleagues identified a natural 18 kDa fragment in human CD40L (hCD40L) that constitutes the extracellular domain of hCD40L, termed soluble CD40L (sCD40L).

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PMC11194678

STAU1 depletion resulted in a decreased autophagosome/autolysosome ratio in STHdh cells.

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PMC9429973

Results: Results: Hard evidence on the incidence and prevalence of MM in the region is scarce, but the experts perceive an increase in MM cases.

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PMC8728081

The ROS of Kajjali treated cells were found to be decreased with increasing concentration (Fig. 3b) due to cell death.

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PMC11680982

Protein concentration was determined by the BCA protein assay.

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PMC11754432

Inhibition of JAK1 reduced CCL2 expression towards basal levels in both control and ALOX15B siRNA transfected cells following treatments with either the cytokine cocktail or IFNγ alone (Fig. 3C).

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PMC11438317

Next, we focused on SKAP1, a close protein to SKAP2 that presents Y232 and Y271, which align with SKAP2 Y237 and Y261, but lacks a Tyr equivalent to SKAP2 Y75.

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PMC11733919

Left: TEM micrograph of as-synthesized MNP@OA and its size distribution (13.2 ± 1.3 nm).

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PMC9275501

Cosco et al. (2015) co-encapsulated RES and 5-FU in ultra-deformable liposomes.

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PMC11777207

Furthermore, we document how the αPD-L1 antibody atezolizumab prevents DC migration of intratumorally transferred DCs.

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PMC11745823

Consistent with previous findings, RIT1 overexpression induced p‐PI3K, p‐AKT and c‐Myc without affecting PI3K and AKT levels (Figure 5A).

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PMC10728200

Inside the cell, the clearance of lipid peroxides primarily relies on the activity of the antioxidant enzyme glutathione peroxidase 4 (GPX4).

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PMC11723947

We therefore decided to exclude them before running further analyses.

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PMC7868205

Biological and chemical methods build particles from the bottom-up.

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PMC9895440

n = 7 donors of n = 2 experiments.

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PMC11742670

model MAE for the A-549 cell line. (

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PMC9424261

Flow cytometry was used to detect lipid ROS.

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PMC11506670

All experiments were conducted at least three times, and each trial involved at least three technical replicates.

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PMC11680562

The morphology of HeLa cells was examined using Giemsa staining under a bright-field microscope.

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PMC11471176

These results regard the new molecule LMS1007 are now under publication in a top journal in drug discovery.

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PMC11525028

mouse models (n = 8 per group), by log-rank test in (H). (

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PMC11683240

For the precipitation analysis, PT (100 ng) and TcdB (50 ng) and inhibitors, α1AT and α-defensin-6 (6 μM) were incubated for 30 min in PBS.

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PMC10798140

Halting of the cell cycle in the G0G1 phase was accompanied by a drop in the percentage of cells in the S phase, indicating that these chemicals can induce cell cycle arrest in the G0G1 phase.

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PMC7294030

In the worldwide, lung cancer is the most common cause of death in men more than women (Pakzad et al., 2015).

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PMC10975211

The resulting buforin conjugate presented better anticancer effects than buforin alone in the pathological-producing MMP cells.

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PMC11476222

However, ganglioside analysis is challenging due to the need for more cost-effective extraction methods and improved accuracy, as their low concentration and the presence of complex biomolecular matrices often interfere with detection and analysis.

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PMC10706275

This is a consequence of foreign gene recombination into chromosomes by random integration.

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PMC11737091

However, the specific mechanisms by which DBF4 functions within the ccRCC immune microenvironment, as well as the potential therapeutic benefits of targeting DBF4 in combination with immunotherapy, require further investigation.

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PMC11748335

The bamCompare program from deepTools was employed to generate BigWig files with the CPM normalization method .

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PMC11607321

Here, a latent representation is a learned, abstracted feature set (embeddings) within the hidden layers of the neural network that encapsulates the major information from the input data.

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PMC9429973

Summary/Conclusion: The elevated oxidative markers and reduced antioxidant support oxidative stress in patients with DLBCL, while MDA can be a prognostic marker of overall survival.

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PMC11742670

The suggested model predicts the IC50of Vidarabine against three cancer cell lines.

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PMC11532793

The use of pseudo- or quasi-alignment makes kallisto and Salmon computationally faster than any splice-aware genome aligner designed for short read sequencing data while providing measurements of the relative expression of individual transcripts directly.

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PMC11641630

Our study has examined both cell migration and invasion, anchorage-independent tumor growth, and active MMP-9 production (via gelatin zymography) using BCG immunotherapy compared to another mycobacterium-based antitumor agent.

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PMC10698968

Scale bar = 100 µm.

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PMC9428827

injections of PBS, wtIL-2 (30,000 IU), or no-alpha mutein (300 IU) twice a day, and the cycle was repeated after one resting week.

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PMC11534377

The groups receiving treatment of 5-Aza alone or in combination with IR exhibited a significant reduction in tumor growth compared to the controls and IR only groups (Figure 12).

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PMC11222184

The results revealed that XL-888 and Debio0932 had a role in regulating many cancer-related pathways such as migration, invasion, metastasis, angiogenesis, and apoptosis in SH-SY5Y cells.

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PMC11659734

These differences underscore the need for developing NAMs, including 3D human tissue models.

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PMC9503669

Of the many known Nef functions, pharmacological suppression of Nef-mediated MHC-I downregulation may be the key to an effective CTL response and viral clearance.

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PMC11673902

Advances in microfluidics will further advance the field, enabling us to realize efficient and reliable cellular mechanical measurements on a larger scale.

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PMC9429973

Twenty-seven of 49 (55%) patients with a FDG PET/CT positive result were MRD negative before KRd consolidation.

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PMC8567602

Others have shown that the fusion's SSXRD domain interacts with a ubiquitin E3 ligase with otherwise established BAF-family component targeting capacity (39).

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PMC11746948

Image in b, c, d, e, g, i shows representative results from three independent experiments.

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PMC11694625

Compared with the standard peaks of NDMA and NDEA in Fig. S19a and b,† no NDMA and NDEA were detected in 3a–3d (Fig. S19c–j†).

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PMC9454178

THZ1 cells (HY-80013A) were purchased from MedChemExpress (MCE, Monmouth Junction, NJ, USA).

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