OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC9325715	For instance, S. Ghosh et al. have investigated the spontaneous process of human serum transferrin fibrillation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "instance", ",", "S.", "Ghosh", "et",...
PMC11075223	Secondly, the traditional uses of Cimicifugae Rhizoma mainly are applied in clinical practice to reflect therapeutic effects while they have not been proven by pharmacological researches.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11783017	As a result, the Cis/Mn/NH@PGP exhibits significant inhibition effect on MYC and promotion on ICD level, thereby resulting in obvious infiltration of T cells for immunotherapy in tumor tissues.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11747885	Rlig1-deficient HEK293 cells exhibit reduced cell viability and RNA integrity under oxidative stress, suggesting Rlig1's role in RNA repair maintenance.	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Rlig1-def...
PMC10196713	Briefly, 1,000-5,000 cells were seeded into each well of a 96-well plate with 100 µl of culture medium/well in triplicate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Briefly...
PMC8658661	There are also no data on the relationship of mutations in the PREX2 gene with hepatoblastoma; however, it has been shown that in 23.5% of patients with HCC, there is a non-silent somatic mutation of PREX2 .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11779993	Western blot analysis showed that keratinocyte HaCaT cells treated with 50 and 100 μg/mL of SPEE exhibited a significant increase in only Rac1 protein expression, while there were no changes in Cdc42 and Rho A expression (Figures 5(a) and 5(b)).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11186948	60x confocal images showing an example of HDAC2 immunocytochemistry on HD LCL and patient LCL (#249); HDAC2 is marked with green signal and nuclei with blue (DAPI); Insets show cell magnification of degree 4 (in HD box) and degree 0 (in #249 box) of HDAC2 nuclear localization. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7841189	These findings suggest that LTBP2 may play an important role in the development and progression of thyroid carcinoma.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "findings", "suggest", "that", ...
PMC11286266	RNA yield was assessed using NanoDrop, and 2 µg of RNA from each sample was evaluated for integrity via electrophoresis on a 1.2% agarose gel.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10440586	The correlation between CD99 expression and the predicted IC50 of PI3K-AKT pathway inhibitors of the TCGA glioma samples.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "correlation", "between", "CD99", ...
PMC3765139	= p ≤ 0.05.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "=", "p", "≤", "0.05", "." ] } ]
PMC9429973	One pt had dose reduction because of grade 2 colitis, and 1 pt receiving 100 mg discontinued because of grade 4 thrombocytopenia.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", ...
PMC9429973	The proportion of ABL1 KD mutation in CML patients with non ABL1 KD mutation (60%) was significantly higher than that in patients without non ABL1 KD mutation (36%) (P=0.022).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8345486	However, in the context of the cytotoxic efficacy of compound 23 in OVCAR-3 and SKOV-3 cells, the significance of mutant p53 induction in apoptosis and inhibition of the cell cycle in these cells might be considered in additional studies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11546117	MCF-10A cells were expanded at a density of 1.5 × 10 cells/cm in normal cell culture flasks (CELLSTAR).	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MCF-10A", "cells", ...
PMC9429973	Methods: Eleven patients diagnosed with hematologic disease (AML, ALL, MDS, and aplastic anemia; 4, 1, 4, and 2, respectively) were enrolled in this study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11437637	Count data were expressed as Number (%) [N (%)].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Count", "data", "were", "expressed", "as", "Number", "(", ...
PMC9100622	These metabolic effects lead to an alteration in the dynamics of S-phase progression and to apoptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "metabolic", "effects", "lead", "to", "an", ...
PMC9429973	In xenograft NOG mouse models, GC012F eliminated B cell lymphoma including DLBCL, MCL and Burkitt lymphoma cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O" ], "tokens": [ "In", "x...
PMC11395280	For these studies, cell migration was measured across a fibronectin-coated polycarbonate transwell membrane at chemokine concentrations ranging from 10 nM to 100 nM (Figure 1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10713411	The role of TRIB3 in tumor development in renal cancer. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "role", "of", "TRIB3", "in", "tumor", "development", "in", "renal", "cancer", ...
PMC11730311	Peptide-based αCGRP antagonists have been considered as potential migraine therapeutics.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Peptide-based", "αCGRP", "antagonists", "have", "been", "considered", "as", "potential", "migraine", ...
PMC9429973	Patients initiated navitoclax at 100 mg once per day (QD) or 200 mg QD if baseline platelet count was ≤150 × 10/L or >150 × 10/L, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Out of 32 pts with RAS mutation, 16 (50%) had single mutation and16 (50%) had multiple RAS mutations, while of 30 pts with KIT mutation, 25 pts (83%) had single KIT mutation, and 5 pts (17%) had multiple KIT mutations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11705630	Therefore, finding a potential therapeutic target for treatment of RCC needs to be investigated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "finding", "a", "potential", "therapeutic", ...
PMC9429973	Data were extracted from the registry and patients’ charts.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "were", "extracted", "from", "the", "registry", "and", "patients", "’", "charts", "...
PMC11549062	Endocytosis is determined as a key step in the regulation of the activity of PDGFR‐β.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Endocytosis", "is", "determined", "as", "a", "key", "step",...
PMC9429973	Relapse treatment was based on the COOPRALL 1997 protocol and since 2008, COPRALL 2007 protocol or the VHR group of the 58951 EORTC protocol.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	MRD by MS was evaluated using both an automated MALDI-TOF (EXENT) and liquid-chromatography-MS (LC-MS) by the Binding Site Group (assays under development).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10840195	Predicted Twist-interacting proteins in the STRING database.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Predicted", "Twist-interacting", "proteins", "in", "the", "STRING", "database", "." ] } ]
PMC9429973	The Gr3-4 AE in >1 pt was sickle cell vaso-occlusion (VOC; 4 [27%]).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "Gr3",...
PMC10932641	All the data were analyzed with SPSS 26.0 statistical software (IBM Corp.), and the measurement data are expressed as the mean ± standard deviation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2193049	Among the MAGE-3–derived peptides binding to HLA-A0201, one peptide, MAGE-3271–279, was able to induce a specific CTL response in vitro when added to a culture of PBL from an HLA-A0201 healthy individual (17).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11756514	For example, SP-D has a high affinity for maltose, not seen for the other two CTLs (67).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "example", ...
PMC10812665	While MPP and Ber were found to have very similar effects on neurons here, MPP is a parkinsonian neurotoxin in vivo , while Ber has been used to treat, e.g., type II diabetes .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8481254	Scale bar, 500 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", ",", "500", "μm", "." ] } ]
PMC11705484	E, F) Cell migration and invasion capabilities were measured by transwell migration and Matrigel invasion assays 48 h after siRNA or expression construct transfections; the cells were fixed with crystal violet.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10759659	a ARID1A-deficient HBV-HCC had a significantly higher tumour mutational burden.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "a", "ARID1A-deficient", "HBV-HCC", "had", "a", "significantly", "higher", "tumour", "mutational", ...
PMC9583612	Here, we describe the measurement framework and results that are central to the QMRV protocol.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Here", ",", "we", "describe", "the", "measurement", ...
PMC10994876	Table 2LATS phosphorylation sites: Conversion of eight serine residues to alanine (S → A) within five LATS consensus sites LATS phosphorylation sites: Conversion of eight serine residues to alanine (S → A) within five LATS consensus sites The results obtained from quantitative PCR (qPCR) demonstrated a significant incr...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10958426	Kaiwen Luo: Data curation.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Kaiwen", "Luo", ":", "Data", "curation", "." ] } ]
PMC4695073	The results demonstrated that XPA expression possessed more prediction value on OS and PFS in the subgroups of younger patients (age≤50), VCA-IgA>1:160, EA-IgA>1:20, or treated with concurrent chemoradiotherapy only or plus induction chemotherapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11344246	Although there are some multi-omics studies described for low-grade serous ovarian cancer (50), this has yet to occur with MOC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Althoug...
PMC11721295	We have re-derived the L-iKRAS model, incorporating current understanding of lung cancer etiology (9–11).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "have", "re-derived", "the", "L-iKRAS", ...
PMC11604830	The error bars correspond to the SD of the SNR in each ROI.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "error", "bars", "correspond", "to", "the", "SD", "of", "the", ...
PMC11622247	They allow detection of specific nucleic acid molecules without the need to separate target-bound from unbound probes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "They", "allow", "detection", "of", "specific", ...
PMC9895440	IL10 secretion is known to correlate with TCR signaling strength, inhibit CD28-signaling, and increase the activation threshold of T cells in a negative-feedback loop, which might be dampened by SNX9 KO.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11297139	Scale bars: 5 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bars", ":", "5", "μm", "." ] } ]
PMC10669128	GEMMs allow us to monitor the effects of induced genetic alterations over time and to evaluate tumor response to treatment in vivo .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GEMMs", "all...
PMC11224206	The most obvious is the ambient temperature in which development occurs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "most", "obvious", "is", "the", "ambient", "temperature", "in", "which", "devel...
PMC11634027	The stronger effects of the D-III deletion could be due to the reduced levels of Ds protein at membranes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "stronger", "effects", "of"...
PMC11638255	Fig. 1Copper chelation potentiates antitumor activity of anti-GD2 immunotherapy.a Experimental design and dosing strategy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "1Copper", "chelation", "potentiates", "antitumor", "activity", ...
PMC10094712	Despite the fact that 25 mammalian selenoproteins were identified several decades ago , the functions of most of them, namely their role in carcinogenesis, are still poorly understood .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10092581	IC50 values were calculated with a four‐parameter logistic (4‐PL) model.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "IC50", "values", "were", "calculated", "with", "a", "four‐parameter", "logistic", ...
PMC9429973	20.014) was used for all statistical analyses.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "20.014", ")", "was", "used", "for", "all", "statistical", "analyses", "." ] } ]
PMC8708099	We demonstrated that Caco-2 cells secrete IL-8 after incubation with histamine, osthole, and FXF in a concentration-dependent manner.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "demonstrated", ...
PMC11476004	The significance of differences between means for a given type of instability within factors was assessed by Tukey’s test (p < 0.05).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10588957	β-Actin was used as an internal control for equal amounts of protein applied.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "β-Actin", "was", "used", "as", "an", "internal", "control", "for", "e...
PMC9429973	The information on dosing and safety is detailed in Table 1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "information", "on", "dosing", "and", "safety", "is", "detailed", "in", "Table"...
PMC11737091	The expression levels of DBF4 were compared in paired tumor and normal samples.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "expression", "levels", "of", "DBF4", "were", "compared", "in", ...
PMC11695623	In addition, we used the online biological database UALCAN to display the protein level of DCUN1D5, which is expressed higher in cancer tissues, and verified this conclusion using wb experiments (Fig. 1G,H).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3164356	N-glycan transferases, mannosyltransferases, sugar-nucleotide synthesis genes and hyaluronoglucosaminidases were enriched for expression or completely expressed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "N-glycan", "transferases", ",", "mannosyltransferases",...
PMC11684297	The hemolysis percentage was calculated using the formula : [12pt] $$ }\\&=} - }} )}}} - }} )}}~ 100~$$ Insulin can form amyloids in vitro if kept under certain controlled conditions , and can act as a model amyloid for the study of amyloidosis .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11224020	g, Transcription factor analysis of the different conditions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "g", ",", "Transcription", "factor", "analysis", "of", "the", "different", "conditions", "." ] } ]
PMC9429973	Results: In vivo deletion of Sucnr1 induced myeloid bias and expansion of the haematopoietic stem and progenitor cell (HSPC) compartment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results...
PMC9429973	Regarding services, 43% had used telemedicine, with more MM patients using this service (61% of MM, 39% of non-MM).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10976516	The study is completed: reolysin did not improve the progress-free survival (PFS vs. single agent chemotherapy (median PFS 3.0 months, 95% confidence interval [CI], 2.6–4.1) vs. 2.8 months (95% CI, 2.5–4.0), hazard ratio (HR) 0.90 (95% CI, 0.65–1.25), p = 0.53).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11696659	Blood samples from all patients in both cohorts were processed by TAT to analyse telomere length from peripheral lymphocytes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Blood", "samples", "from", "all",...
PMC10899471	The primer sets and restriction enzymes were listed in Supplementary Table S4 .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "primer", "sets", "and", "restriction", "enzymes", "were", "listed", "in",...
PMC9325715	For studies, the L929 cell line and Caco-2 cell line were selected.	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O" ], "tokens": [ "For", "studies", ",", "the", "L929", "cell", "line", "and...
PMC9599726	VP significantly increased ferrous iron concentration in both GIST882 and GIST48 cells after 24 h. CA3 exhibited only a minor non-significant increase in ferrous iron in GIST48 cells, but not in GIST882 cells (Figure 6A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC9429973	We used various syngeneic murine AML models (e.g. MLL/AF9 and MLL/ENL) to study the functional role of IL21/IL21R signaling in vivo.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", ...
PMC11648299	The diagnosis of DD was recorded in the patient records and sent to NPR only after the histopathological diagnosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "diagnosis", "of", "DD", ...
PMC11552389	After plating cells in 96-well plates and the supplied One Solution reagent was aliquoted into each well.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "plating", "cells", "in", "96-well", ...
PMC11725127	Moreover, USP2 knockout-induced KRAS downregulation could be rescued by the proteasome inhibitor MG132 in both cell lines (Fig. 4E and F).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11759751	Chidamide was obtained from Chipscreen Biosciences, dissolved in DMSO as per the manufacturer’s instructions, and stored at −80 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Chidami...
PMC11011837	In this study, metabolic and lipidomic analysis via LC/MS have been carried out on four T-ALL cell lines belonging to the TAL/LMO subgroup (Jurkat, Molt-4, Molt-16, and CCRF-CEM) to identify new potential metabolic biomarkers and to provide a subclassification of T-ALL cell lines belonging to the same subgroup.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", ...
PMC11661024	Several Bcl-2 family members can operate as proapoptotic proteins (e.g., Bax and Bak), while Bcl-2 can be an anti-apoptotic protein .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11634027	Top three panels show blots of cell lysates expressing the indicated proteins, using the antibodies indicated on the right.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Top", "three", "panels", ...
PMC10810426	Indeed, MLV encodes a protein called glycosylated Gag (glycoGag) protein that enhances capsid stability and prevents APOBEC3 and nucleic acid sensors from accessing the RTC .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11583010	A, Schematic representation of ETx-22.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", ",", "Schematic", "representation", "of", "ETx-22", "." ] } ]
PMC11760643	The authors declare no conflicts of interest.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "authors", "declare", "no", "conflicts", "of", "interest", "." ] } ]
PMC10969097	The main objectives were to determine the dosage of PSK in conjunction with docetaxel as well as to conduct pharmacokinetic analyses.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "main", "ob...
PMC11711127	The authors demonstrated that deletion of IRF8 specific to TAMs prevents CTL exhaustion and hampers tumour growth.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "authors", "demonstrated", "that", "deletio...
PMC8389560	In medicine, the use of SeNP can solve one of the main problems—the resistance of cancer cells to chemotherapeutic drugs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC11507371	In HaCaT cells, a significant elevation in IκBα translocation was noted after 120 (+18%), 150 (+21%), and 180 s (+30%).	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11674891	In lung cancer, Crabp2 expression is elevated in highly metastatic mouse lung cancer cells compared to less metastatic counterparts, facilitating integrin β1/FAK/ERK signaling .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11402217	GO analysis of biological processes affected by regulated genes. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GO", "analysis", "of", "biological", "processes", "affected", "by", "regulated", "genes", ".", ...
PMC11587541	Further research is needed to fully understand the role of telomere shortening in SMA and to develop effective therapies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Further", "research", "is", "need...
PMC11468365	ReLU is used as the activation function following each FC layer, with a dropout rate of 0.2 applied after both the first and second FC layers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11791478	The translocation of surface-bound proteins to the intracellular compartment was tracked through a series of time-lapse images.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "translocation", "of", "surface-bound", "pr...
PMC9429973	Results: From 1972 to 2021, 534 cases of neutropenia/leukopenia were recorded (5, 40, 82, 134, 273 during 1970-1979, 1980-1989, 1990-1999, 2000-2009, 2010-2021, respectively); 152 were included in the cross-sectional study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11742231	By doing so, the model can extract complementary information from different sources and produce more comprehensive and reliable predictions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "By", "doing", "so", ",...
PMC11618052	0.57 (hexane : ethyl acetate, 1 : 2, v/v).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "0.57", "(", "hexane", ":", "ethyl", "acetate", ",", "1", ":", "...
PMC11803149	Although there are conflicting reports and it remains controversial (12–14), several animal studies reported negative impacts of aging on anti-tumor CD8 T cell responses and immune checkpoint blockade responses (15–19).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11295144	GABAARs themselves participate in inhibitory synaptogenesis as structural (Fuchs et al., 2013; Brown et al., 2014, 2016; Duan et al., 2019) and signaling (Pallotto and Deprez, 2014; Arama et al., 2015; Cherubini and Ben-Ari, 2023) components and contribute to the functional specialization of synapses via the incorporat...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11599565	Interfering Notch and MAP4K4 signaling pathways in OC cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interfering", "Notch", "and", "MAP4K4", "signaling", "pathways", "in", "OC", "cells", "." ] } ]
PMC11531744	Moreover, the prognostic model had other effects on clinical applications, for example using these genes to find potential therapeutic targets and drugs, which may provide new ideas for the diagnosis and treatment of OC (Fig. 6).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11792740	Lu et al. found that suppression of the MondoA-TXNIP axis promoted glucose uptake and glycolysis and induced hyperglycolytic Th17-like Tregs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lu", "et", "al.", "fou...

PMC9325715

For instance, S. Ghosh et al. have investigated the spontaneous process of human serum transferrin fibrillation.

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PMC11075223

Secondly, the traditional uses of Cimicifugae Rhizoma mainly are applied in clinical practice to reflect therapeutic effects while they have not been proven by pharmacological researches.

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PMC11783017

As a result, the Cis/Mn/NH@PGP exhibits significant inhibition effect on MYC and promotion on ICD level, thereby resulting in obvious infiltration of T cells for immunotherapy in tumor tissues.

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PMC11747885

Rlig1-deficient HEK293 cells exhibit reduced cell viability and RNA integrity under oxidative stress, suggesting Rlig1's role in RNA repair maintenance.

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PMC10196713

Briefly, 1,000-5,000 cells were seeded into each well of a 96-well plate with 100 µl of culture medium/well in triplicate.

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PMC8658661

There are also no data on the relationship of mutations in the PREX2 gene with hepatoblastoma; however, it has been shown that in 23.5% of patients with HCC, there is a non-silent somatic mutation of PREX2 .

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PMC11779993

Western blot analysis showed that keratinocyte HaCaT cells treated with 50 and 100 μg/mL of SPEE exhibited a significant increase in only Rac1 protein expression, while there were no changes in Cdc42 and Rho A expression (Figures 5(a) and 5(b)).

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PMC11186948

60x confocal images showing an example of HDAC2 immunocytochemistry on HD LCL and patient LCL (#249); HDAC2 is marked with green signal and nuclei with blue (DAPI); Insets show cell magnification of degree 4 (in HD box) and degree 0 (in #249 box) of HDAC2 nuclear localization. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7841189

These findings suggest that LTBP2 may play an important role in the development and progression of thyroid carcinoma.

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PMC11286266

RNA yield was assessed using NanoDrop, and 2 µg of RNA from each sample was evaluated for integrity via electrophoresis on a 1.2% agarose gel.

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PMC10440586

The correlation between CD99 expression and the predicted IC50 of PI3K-AKT pathway inhibitors of the TCGA glioma samples.

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PMC3765139

= p ≤ 0.05.

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PMC9429973

One pt had dose reduction because of grade 2 colitis, and 1 pt receiving 100 mg discontinued because of grade 4 thrombocytopenia.

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PMC9429973

The proportion of ABL1 KD mutation in CML patients with non ABL1 KD mutation (60%) was significantly higher than that in patients without non ABL1 KD mutation (36%) (P=0.022).

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PMC8345486

However, in the context of the cytotoxic efficacy of compound 23 in OVCAR-3 and SKOV-3 cells, the significance of mutant p53 induction in apoptosis and inhibition of the cell cycle in these cells might be considered in additional studies.

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PMC11546117

MCF-10A cells were expanded at a density of 1.5 × 10 cells/cm in normal cell culture flasks (CELLSTAR).

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PMC9429973

Methods: Eleven patients diagnosed with hematologic disease (AML, ALL, MDS, and aplastic anemia; 4, 1, 4, and 2, respectively) were enrolled in this study.

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PMC11437637

Count data were expressed as Number (%) [N (%)].

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PMC9100622

These metabolic effects lead to an alteration in the dynamics of S-phase progression and to apoptosis.

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PMC9429973

In xenograft NOG mouse models, GC012F eliminated B cell lymphoma including DLBCL, MCL and Burkitt lymphoma cell lines.

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PMC11395280

For these studies, cell migration was measured across a fibronectin-coated polycarbonate transwell membrane at chemokine concentrations ranging from 10 nM to 100 nM (Figure 1).

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PMC10713411

The role of TRIB3 in tumor development in renal cancer. (

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PMC11730311

Peptide-based αCGRP antagonists have been considered as potential migraine therapeutics.

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PMC9429973

Patients initiated navitoclax at 100 mg once per day (QD) or 200 mg QD if baseline platelet count was ≤150 × 10/L or >150 × 10/L, respectively.

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PMC9429973

Out of 32 pts with RAS mutation, 16 (50%) had single mutation and16 (50%) had multiple RAS mutations, while of 30 pts with KIT mutation, 25 pts (83%) had single KIT mutation, and 5 pts (17%) had multiple KIT mutations.

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PMC11705630

Therefore, finding a potential therapeutic target for treatment of RCC needs to be investigated.

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PMC9429973

Data were extracted from the registry and patients’ charts.

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PMC11549062

Endocytosis is determined as a key step in the regulation of the activity of PDGFR‐β.

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PMC9429973

Relapse treatment was based on the COOPRALL 1997 protocol and since 2008, COPRALL 2007 protocol or the VHR group of the 58951 EORTC protocol.

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PMC9429973

MRD by MS was evaluated using both an automated MALDI-TOF (EXENT) and liquid-chromatography-MS (LC-MS) by the Binding Site Group (assays under development).

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PMC10840195

Predicted Twist-interacting proteins in the STRING database.

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PMC9429973

The Gr3-4 AE in >1 pt was sickle cell vaso-occlusion (VOC; 4 [27%]).

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PMC10932641

All the data were analyzed with SPSS 26.0 statistical software (IBM Corp.), and the measurement data are expressed as the mean ± standard deviation.

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PMC2193049

Among the MAGE-3–derived peptides binding to HLA-A*0201, one peptide, MAGE-3271–279, was able to induce a specific CTL response in vitro when added to a culture of PBL from an HLA-A*0201 healthy individual (17).

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PMC11756514

For example, SP-D has a high affinity for maltose, not seen for the other two CTLs (67).

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PMC10812665

While MPP and Ber were found to have very similar effects on neurons here, MPP is a parkinsonian neurotoxin in vivo , while Ber has been used to treat, e.g., type II diabetes .

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PMC8481254

Scale bar, 500 μm.

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PMC11705484

E, F) Cell migration and invasion capabilities were measured by transwell migration and Matrigel invasion assays 48 h after siRNA or expression construct transfections; the cells were fixed with crystal violet.

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PMC10759659

a ARID1A-deficient HBV-HCC had a significantly higher tumour mutational burden.

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PMC9583612

Here, we describe the measurement framework and results that are central to the QMRV protocol.

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PMC10994876

Table 2LATS phosphorylation sites: Conversion of eight serine residues to alanine (S → A) within five LATS consensus sites LATS phosphorylation sites: Conversion of eight serine residues to alanine (S → A) within five LATS consensus sites The results obtained from quantitative PCR (qPCR) demonstrated a significant incr...

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PMC10958426

Kaiwen Luo: Data curation.

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PMC4695073

The results demonstrated that XPA expression possessed more prediction value on OS and PFS in the subgroups of younger patients (age≤50), VCA-IgA>1:160, EA-IgA>1:20, or treated with concurrent chemoradiotherapy only or plus induction chemotherapy.

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PMC11344246

Although there are some multi-omics studies described for low-grade serous ovarian cancer (50), this has yet to occur with MOC.

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PMC11721295

We have re-derived the L-iKRAS model, incorporating current understanding of lung cancer etiology (9–11).

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PMC11604830

The error bars correspond to the SD of the SNR in each ROI.

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PMC11622247

They allow detection of specific nucleic acid molecules without the need to separate target-bound from unbound probes.

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PMC9895440

IL10 secretion is known to correlate with TCR signaling strength, inhibit CD28-signaling, and increase the activation threshold of T cells in a negative-feedback loop, which might be dampened by SNX9 KO.

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PMC11297139

Scale bars: 5 μm.

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PMC10669128

GEMMs allow us to monitor the effects of induced genetic alterations over time and to evaluate tumor response to treatment in vivo .

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PMC11224206

The most obvious is the ambient temperature in which development occurs.

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PMC11634027

The stronger effects of the D-III deletion could be due to the reduced levels of Ds protein at membranes.

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PMC11638255

Fig. 1Copper chelation potentiates antitumor activity of anti-GD2 immunotherapy.a Experimental design and dosing strategy.

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PMC10094712

Despite the fact that 25 mammalian selenoproteins were identified several decades ago , the functions of most of them, namely their role in carcinogenesis, are still poorly understood .

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PMC10092581

IC50 values were calculated with a four‐parameter logistic (4‐PL) model.

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PMC9429973

20.014) was used for all statistical analyses.

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PMC8708099

We demonstrated that Caco-2 cells secrete IL-8 after incubation with histamine, osthole, and FXF in a concentration-dependent manner.

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PMC11476004

The significance of differences between means for a given type of instability within factors was assessed by Tukey’s test (p < 0.05).

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PMC10588957

β-Actin was used as an internal control for equal amounts of protein applied.

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PMC9429973

The information on dosing and safety is detailed in Table 1.

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PMC11737091

The expression levels of DBF4 were compared in paired tumor and normal samples.

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PMC11695623

In addition, we used the online biological database UALCAN to display the protein level of DCUN1D5, which is expressed higher in cancer tissues, and verified this conclusion using wb experiments (Fig. 1G,H).

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PMC3164356

N-glycan transferases, mannosyltransferases, sugar-nucleotide synthesis genes and hyaluronoglucosaminidases were enriched for expression or completely expressed.

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PMC11684297

The hemolysis percentage was calculated using the formula : [12pt] $$ }\\&=} - }} )}}} - }} )}}~ 100~$$ Insulin can form amyloids in vitro if kept under certain controlled conditions , and can act as a model amyloid for the study of amyloidosis .

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PMC11224020

g, Transcription factor analysis of the different conditions.

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PMC9429973

Results: In vivo deletion of Sucnr1 induced myeloid bias and expansion of the haematopoietic stem and progenitor cell (HSPC) compartment.

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PMC9429973

Regarding services, 43% had used telemedicine, with more MM patients using this service (61% of MM, 39% of non-MM).

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PMC10976516

The study is completed: reolysin did not improve the progress-free survival (PFS vs. single agent chemotherapy (median PFS 3.0 months, 95% confidence interval [CI], 2.6–4.1) vs. 2.8 months (95% CI, 2.5–4.0), hazard ratio (HR) 0.90 (95% CI, 0.65–1.25), p = 0.53).

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PMC11696659

Blood samples from all patients in both cohorts were processed by TAT to analyse telomere length from peripheral lymphocytes.

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PMC10899471

The primer sets and restriction enzymes were listed in Supplementary Table S4 .

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PMC9325715

For studies, the L929 cell line and Caco-2 cell line were selected.

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PMC9599726

VP significantly increased ferrous iron concentration in both GIST882 and GIST48 cells after 24 h. CA3 exhibited only a minor non-significant increase in ferrous iron in GIST48 cells, but not in GIST882 cells (Figure 6A).

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PMC9429973

We used various syngeneic murine AML models (e.g. MLL/AF9 and MLL/ENL) to study the functional role of IL21/IL21R signaling in vivo.

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PMC11648299

The diagnosis of DD was recorded in the patient records and sent to NPR only after the histopathological diagnosis.

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PMC11552389

After plating cells in 96-well plates and the supplied One Solution reagent was aliquoted into each well.

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PMC11725127

Moreover, USP2 knockout-induced KRAS downregulation could be rescued by the proteasome inhibitor MG132 in both cell lines (Fig. 4E and F).

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PMC11759751

Chidamide was obtained from Chipscreen Biosciences, dissolved in DMSO as per the manufacturer’s instructions, and stored at −80 °C.

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PMC11011837

In this study, metabolic and lipidomic analysis via LC/MS have been carried out on four T-ALL cell lines belonging to the TAL/LMO subgroup (Jurkat, Molt-4, Molt-16, and CCRF-CEM) to identify new potential metabolic biomarkers and to provide a subclassification of T-ALL cell lines belonging to the same subgroup.

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PMC11661024

Several Bcl-2 family members can operate as proapoptotic proteins (e.g., Bax and Bak), while Bcl-2 can be an anti-apoptotic protein .

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PMC11634027

Top three panels show blots of cell lysates expressing the indicated proteins, using the antibodies indicated on the right.

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PMC10810426

Indeed, MLV encodes a protein called glycosylated Gag (glycoGag) protein that enhances capsid stability and prevents APOBEC3 and nucleic acid sensors from accessing the RTC .

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PMC11583010

A, Schematic representation of ETx-22.

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PMC11760643

The authors declare no conflicts of interest.

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PMC10969097

The main objectives were to determine the dosage of PSK in conjunction with docetaxel as well as to conduct pharmacokinetic analyses.

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PMC11711127

The authors demonstrated that deletion of IRF8 specific to TAMs prevents CTL exhaustion and hampers tumour growth.

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PMC8389560

In medicine, the use of SeNP can solve one of the main problems—the resistance of cancer cells to chemotherapeutic drugs.

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PMC11507371

In HaCaT cells, a significant elevation in IκBα translocation was noted after 120 (+18%), 150 (+21%), and 180 s (+30%).

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PMC11674891

In lung cancer, Crabp2 expression is elevated in highly metastatic mouse lung cancer cells compared to less metastatic counterparts, facilitating integrin β1/FAK/ERK signaling .

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PMC11402217

GO analysis of biological processes affected by regulated genes. (

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PMC11587541

Further research is needed to fully understand the role of telomere shortening in SMA and to develop effective therapies.

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PMC11468365

ReLU is used as the activation function following each FC layer, with a dropout rate of 0.2 applied after both the first and second FC layers.

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PMC11791478

The translocation of surface-bound proteins to the intracellular compartment was tracked through a series of time-lapse images.

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PMC9429973

Results: From 1972 to 2021, 534 cases of neutropenia/leukopenia were recorded (5, 40, 82, 134, 273 during 1970-1979, 1980-1989, 1990-1999, 2000-2009, 2010-2021, respectively); 152 were included in the cross-sectional study.

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PMC11742231

By doing so, the model can extract complementary information from different sources and produce more comprehensive and reliable predictions.

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PMC11618052

0.57 (hexane : ethyl acetate, 1 : 2, v/v).

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PMC11803149

Although there are conflicting reports and it remains controversial (12–14), several animal studies reported negative impacts of aging on anti-tumor CD8 T cell responses and immune checkpoint blockade responses (15–19).

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PMC11295144

GABAARs themselves participate in inhibitory synaptogenesis as structural (Fuchs et al., 2013; Brown et al., 2014, 2016; Duan et al., 2019) and signaling (Pallotto and Deprez, 2014; Arama et al., 2015; Cherubini and Ben-Ari, 2023) components and contribute to the functional specialization of synapses via the incorporat...

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PMC11599565

Interfering Notch and MAP4K4 signaling pathways in OC cells.

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PMC11531744

Moreover, the prognostic model had other effects on clinical applications, for example using these genes to find potential therapeutic targets and drugs, which may provide new ideas for the diagnosis and treatment of OC (Fig. 6).

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PMC11792740

Lu et al. found that suppression of the MondoA-TXNIP axis promoted glucose uptake and glycolysis and induced hyperglycolytic Th17-like Tregs.

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