OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC9429973	Results: Between January 2020- February 2022, 75 patients with HN and COVID19 infection were identified.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "Between", "January", "2020-", ...
PMC10551595	Cell apoptosis rate was determined using the BioLegend kit (BioLegend).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "apoptosis", "rate", "was", "determined", "using", "the", "BioLegend", "k...
PMC6889484	Average of two independent infections per ratio is indicated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Average", "of", "two", "independent", "infections", "per", "ratio", "is", "indicated", "." ] } ]
PMC11615743	Validation of L‐DNA device for target cell labeling via a dual‐aptamer‐based logic gate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Validation", "of", "L‐DNA", "device", "for", "target", "cell", "labeling", ...
PMC10362265	The best structure was selected based on the discrete optimized protein energy score .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "best", "structure", "was", "selected", "based", "on", "the", "...
PMC9918897	Xanthohumol administered to mice orally in a water–alcohol-based matrix did not have a direct protective effect on tumor growth (induced by the injection of HeLa tumorigenic cell lines) and did not have a positive effect on plasma antioxidant capacity either.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11721587	The luciferase activity was determined using dual-luciferase reporter assay system (Promega) and FLUOstar OPTIMA (BMG Labtech).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "luciferase", "activit...
PMC8524093	Although CHIKF is known as a non-deadly disease, atypical and severe acute manifestations can evolve to multiple organ failure and death.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Although", "...
PMC11402217	The stagnation in developing new treatments for metastatic OS over the last thirty years has stalled clinical advancements, underlining the critical need for more effective, targeted therapies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	A greater proportion of M1 macrophages were present in patients with GCB compared to ABC COO subtype (Kruskal Wallis chi-squared 7.66, p value <0.01).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11564405	A total of 140 patients who had been diagnosed with primary NSCLC (including 66 lung adenocarcinomas and 74 lung squamous cell carcinomas) were enrolled in our study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11699465	Trucked TMEM199 sequences were amplified and assembled into the expression vectors with Flags.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Trucked", "TMEM199", "sequences", "were", "amplified", "and", "assembled", ...
PMC8409415	Among 63 OvCA surgical specimens, there were 29 women who received NACT before cytoreductive surgery.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Among", "63", "OvCA", "surgical", "specimens", ",", ...
PMC11509278	Ethanol (70%) extract of Cuban red propolis exhibited antiproliferative and cytotoxic effects on MDA MB-231 cells, probably related to PI3K/Akt and ERK1/2 pathways .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "...
PMC9429973	The anti-HTN drugs were categorized as follows: 1) Angiotensin-converting-enzyme inhibitors and Angiotensin receptor blockers (ACEi/ARB); 2) Beta-blockers (BB); 3) Calcium channel blockers (CCB); 4) Hydrochlorothiazide (HCTZ) and 5) non-HCTZ diuretics (other-DU).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6901583	This work showed the involvement of this pathway in the increased expression of CCL2 induced by BRD4.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "work", "showed", "the", "involvement", ...
PMC10747160	A total of 20 μg mL of mannan also appears to efficiently prevent all strains’ trans-infection, thereby demonstrating that the presence of additional structural proteins does not impair DC-SIGN’s ability to bind to viral surface glycoproteins and facilitate trans-infection (Figure 7D,E and Figure S10).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9895440	This procedure was repeated (with IL-2 stimulation at each stimulation) according to the scheme in Supplementary Fig. 1a.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "procedure", "was", ...
PMC8567602	This model is supported by the observation that proteasome inhibition blunts CBAF-specific component reductions in the presence of the fusion (Fig. 7H and I).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10291556	This suggests that the presence of the ethylenediamine linker, if it remains attached to DCF, does not qualitatively affect the resulting biological properties.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11301095	Fig. 1Brain MRI images.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "1Brain", "MRI", "images", "." ] } ]
PMC10197932	These cytokines are important for the survival and proliferation of naïve T and mainly cytotoxic cells 46.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "cytokines", "are", "important", "for", ...
PMC10759659	Overall, 425 HBV-related hepatocellular carcinoma patients were enrolled in the study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Overall", ",", "425", "HBV-related", "hepatocellular", "carcinoma", "patients", "were"...
PMC5535901	Indole-3-carbinol (I3C) and its dimer diindolylmethane (DIM) are bioactive metabolites of a glucosinolate, glucobrassicin, found in cruciferous vegetables.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10877303	Fig. 8 The binding-free energy of the top three drugs and inhibitor complexes calculated by the MM-PBSA method.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "8", "The", "binding-free", "en...
PMC11769516	These substances were evaluated for their chemical composition and found to contain polyphenols, which indicated their potential in the treatment of mycotoxin poisoning.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9583612	This verification must go beyond satisfying a checklist of operator actions but involve academic experts who can provide an independent evaluation of all relevant data.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11740207	These findings suggest that HL60 retains a hierarchical structure similar to that observed in vivo, with distinct subpopulations contributing to disease progression and treatment resistance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973	The tolerability profile of the combination regimens was manageable, with no unexpected safety concerns.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "tolerability", "profile", "of", "the", "combination", ...
PMC10812665	For such compounds, information spanning from molecular target interaction to in vivo adverse outcomes is available.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "such", "compounds", ",", "information", ...
PMC11694066	All animal procedures and studies were performed in accordance with the approved guidelines for animal experimentation by the Ethics Committee at the Université Paris-Sud (CEEA 26, project 2014_055_2790) following EU regulation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11706776	Further studies are needed to identify the calcium channel components (such as the Orai and TRP families) associated with SK1 in ES cell.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10452486	Each alpha and beta chain comprises groove (G-ALPHA [D1] and G-BETA [D1]) and constant (C-like ALPHA [D2] and C-like BETA [D2]) domains .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10808409	The larger the coefficient, the more the influence of that factor on the studied response.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "larger", "the", "coefficient", ",", "the", ...
PMC11476837	Under homeostatic conditions, NRF2 is maintained at low levels in the cytosol through its interaction with KEAP1, which directs NRF2 toward proteasome.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11348300	The mice were housed in the Dartmouth central animal facility and fed special diet—MP biomedical purified diet.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mice", "were", "housed", ...
PMC10040136	In summary, this study points to the capability of MSC to promote GIST resistance in targeted therapies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "summary", ",", "this", "study", ...
PMC11290772	Remarkably, the findings of this investigation underscored the remarkable efficacy of ROBO1-NK cells in selectively eliminating tumor cells and organoids.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Remarkably", ",", ...
PMC11525028	The antibodies for western blot assay were provided in Table S11.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "antibodies", "for", "western", "blot", "assay", "were", "provided", "in", "Tab...
PMC11594641	MITF is known to regulate the expression of late endosomal proteins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MITF", "is", "known", "to", "regulate", "the", "expression", "of", "late", "endosomal...
PMC10914904	Some svtRNAs can be loaded into AGO2, regulating posttranscriptional gene silencing It has been reported that vtRNA1-1 may not undergo cleavage by DICER .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10975211	Understanding these natural peptides holds significant potential for developing effective and targeted therapies against cancer and infectious diseases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Understanding", "these", "natural", "peptide...
PMC11738017	In the recently reported trial with linvoseltamab at sBCMA levels ≥ 400 ng/mL, a 200-mg TCE dose significantly improved the overall response when compared with a dose of 50 mg.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Image: Summary/Conclusion: Our cohort confirms that BNS may present with leptomeningeal disease and/or parenchymal disease, de novo and without systemic disease.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11774112	The calculated IC50 in the PHRD-DTIC and PHRD- miRNA 34a was lower than free DTIC and free miRNA 34a groups at 72 h (2.609 ± 2.425 µg/mL vs 6.287 ± 4.106 µg/mL; 1.81 ± 5.13 µg/mL vs 1.894 ± 4.627 µg/mL, respectively).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10812665	The procedure was used as detailed earlier .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "procedure", "was", "used", "as", "detailed", "earlier", "." ] } ]
PMC9325715	FTIR analysis was performed for both native bLTF and modified with Fe in the MIR range (4000–400 cm).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "FTIR", "analysis", "was", ...
PMC8978939	Protein residues were treated using the AMBER ff14SB force field.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Protein", "residues", "were", "treated", "using", "the", "AMBER", "ff14SB", "force", "field", ...
PMC10203589	In the process of exploring FGF18 and non-coding RNA mediated HCC progression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "process", "of", "exploring", "FGF18", "and", "non-coding", "RNA", ...
PMC11269792	The above-mentioned reporter gene vector, along with miR-6838-5p mimic or mimic NC was co-transfected into GIST-882 cells (5×10) in the 24-well plates using Lipofectamine 2000 (Invitrogen).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9964654	Water led to the micelle formulation AS4 standing out as the one with the highest [Au(cdc)2] loading content (LC (mg[Au(cdc)2]−/gBCM) = 5.68).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11085211	IC50 was instead calculated with the free “aatbioquest” tool (https://www.aatbio.com/tools/ic50-calculator, accessed on 11 April 2024).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "IC50", "was", "instead", ...
PMC11684821	The bias toward TRAJ42 use and conservation of a semi-invariant motif makes it tempting to speculate that the cells we describe across multiple donors likely exhibit limited antigen diversity and might bind to an identical MR1-bound cargo at the cancer cell surface.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10135767	When lymphocytes are recruited to inflammatory regions, cytoplasmic Ca acts as a signaling molecule to facilitate the transformation of the cell state from rolling to arrest to achieve functional activation .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11186948	The subject and its family gave informed consent.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "subject", "and", "its", "family", "gave", "informed", "consent", "." ] } ]
PMC11248911	The formed precipitate was filtered, washed with water and dried to give the corresponding thiazolidinone derivatives.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "formed", "precipitate", "was", "filtered",...
PMC7154001	The title and abstract of each article search from PubMed (via Endnote) and ScienceDirect databases using the keywords mentioned above were initially screened for relevant original articles based on the inclusion and exclusion criteria.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9424261	Next, we examined whether HERPUD1 played a vital role in increasing the sensitivity of liver cancer cells to ferroptosis following CA treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Next", ...
PMC11424574	The shLuc- and shMTA2-osteosarcoma cells (1×10/well) were seeded in 6-well plate and incubated for 7 days, then stained with crystal violet reagent (1:20) for 30 mins.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11473843	To establish an in vitro model mimicking FAK inhibitor resistance in NSCLC, we treated A549 cells with increasing doses of VS-4718, which resulted in the enrichment of drug-resistant cells that were characterized by slow proliferation and a mesenchymal-like morphology (Fig. 5A,B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11225860	This cell progresses through G1 but fails entry into S/G2 (Fig. 5c and Sup Fig. 5c).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "cell", "progresses", "through", ...
PMC11792766	Cells were subcultured under sterile conditions to 80%–90% confluence at 37°C and 5% CO2 and detached using 0.25% v/v trypsin‐EDTA phenol red solution.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4369959	Ginger extract not only inhibits carcinogenesis of colorectal cancer cells but also enhances the anticancer effects of chemotherapeutic drug 5-fluorouracil.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ginger", "extract", "not", ...
PMC11459296	We evaluated the functionality of the transplanted human immune cells both ex vivo and in vivo.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "evaluated", "the", "functionality", "of", "the",...
PMC11770199	Therefore, we next construed the engineered MSCs carrying a coding gene of p14 protein (MSCs-p14) and tested their antitumor therapeutic effect in vitro and in vivo.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11190062	BCMA is a target for CAR T cells and bispecific antibodies approved to treat MM patients (36).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "BCMA", "is", "a", "target", ...
PMC11248911	Anal.	[ { "tags": [ "O", "O" ], "tokens": [ "Anal", "." ] } ]
PMC11337594	A375 cells were treated with TER (2 µg/ml) for 24 h, and the images show the distribution of Ki67 (red) protein. (	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11535726	Conidia 30–55 × 9–13.5 μm (x̄ = 40 × 11.1 µm, n = 30), solitary, acrogenous, cylindrical, oblong and occasionally clavate, smooth, guttulate, 2–4-septate, slightly or deeply constricted and darker at the septa, brown, rounded at the apex and sometimes truncate at the base, exhibiting obtuse ends.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11258145	Due to the fact that the use of curcumin in liposomal form is becoming more and more common, the concentration of this compound, in cells can reach much higher level, definitely exceeding the amounts that can enter the body when applied in natural form.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11429241	The 3D cell cultures without the scaffold were made following protocol , and 14,000 cells were seeded per well.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "3D", "cell", "cultures", ...
PMC9985266	In conclusion, our study shows that IL-27 upregulates MEG3 expression through inhibition of DNMT1-mediated lncRNA MEG3 promoter methylation, which in turn inhibits ERK/p38 signaling pathway-induced autophagy and attenuates BLM-induced PF, providing a contribution to the elucidation of the potential mechanisms by which ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11323699	However, after informed consent from participating patients, paired formalin-fixed, paraffin-embedded (FFPE) tumor samples were obtained at diagnosis and after 3 cycles of NACT in order to study changes in iTME during NACT.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11185260	In comparison, the body weight of mice receiving scL-SMARCB1 treatment remained stable for an extended period before rapidly decreasing as the tumor burden increased.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9512971	From these data, we therefore considered it was possible to demonstrate the superiority of camostat mesilate over placebo with a sample size of 100 patients (50 patients per group).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11543935	B: HE staining of untreated control with homogenic staining of the ECM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "B", ":", "HE", "staining", "of", "untreated", "control", "with", "hom...
PMC11700247	Data represent irradiated tumors from the fractionated- or single-dose–treated groups. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "represent", "irradiated", "tumors", "from", "the", "fractionated-", ...
PMC11349530	Conditioned media derived from lung cancer cells induced pro-tumoral phenotypes in macrophages (15).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Conditioned", "media", "derived", "from", "lung", "cancer", ...
PMC7189327	However, the influence of these two genes on BCC pathogenesis has not been fully investigated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "the", "influence", "of", "these", ...
PMC11468365	The value ranges from 0 to 1, where 0 indicates a poor prediction model and 1 indicates a perfect prediction model.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "value...
PMC11569208	Fluorescent foci were counted 24 h post infection (hpi) and expressed as fold-change over the infected-only condition (n = 3, mean). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	To estimate the penetrance of NMs associated with pathogenic germline variants, we calculated cumulative incidence of MN in a cohort of 384 first-degree relatives (kin-cohort) of DDX41-mutated NM cases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11257988	MicroRNAs (miRNAs) are another important class of non-coding RNAs that play a role in gene regulation by degrading mRNA or inhibiting translation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10094712	Origin v8.5 (Microcal Software Inc., Northampton, MA, USA) and Prism 5 (GraphPad Software, La Jolla, CA, USA) were used for plotting the data and statistical processing.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11655498	In contrast, EBV miR-BHRF1-2-5p, miR-BART2-5p, and the host miR-17-5p have been shown to weaken the BCR-mediated reactivation of EBV in vivo (Chen et al., 2019).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	For pZAP70 mean RFI in CD4+ cells was 8.8 in controls compared with 2.2 in rux patients (p=0.05).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "pZAP70", "...
PMC11782508	d-f) Cell cycle analysis by propidium iodide staining. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "d-f", ")", "Cell", "cycle", "analysis", "by", "propidium", "iodide", "staining", ".", "(" ...
PMC11615101	Briefly, 100µl of plasma sample was added to the pre-coated ELISA plate (provided) along with the standard and incubated for 120min at 37°C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10900886	Human rhabdomyosarcoma (RD) cells were cultured in DMEM (Lonza) supplemented with 10% FBS and PSG.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Human", "rhabdomyosarcoma...
PMC10808409	Q1: shows necrotic cells, Q2: shows later period apoptotic cells, Q3: shows normal cells, Q4: shows early apoptotic cells. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7192625	Comprehensive epigenomic data was collected for neutrophils, including four histone modifications, DNA methylation and expression levels across all individuals, allowing us to test the robustness of our findings in this cell type.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10040136	1Proportion of MSC in clinical samples correlates with Imatinib resistance and prognosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "1Proportion", "of", "MSC", "in", "clinical", "samples", "correlates", "with", "I...
PMC11045125	Consistent with this possibility, we found that the one ΔEBNA2 + Myc tumor-derived cell line (“R3”) that constitutively expresses LMP1 when grown off the CD40L/IL21 expressing feeder cell layer also has a much higher level of total STAT3, phosphorylated STAT3, and Src in comparison to the other cell lines that do not e...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10452486	Notably, these two categories differed in their glycosylation (mannose residues), density, and location on the cell surface.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notably", ",...
PMC11742670	Among them, the simplest and cheapest ones were prioritized for the next WET LAB phase.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Among", "them", ",", "the", "simplest", "and", "...
PMC11185260	Taken together, these results indicate that combining radiation with scL-SMARCB1 is more effective and safer than conventional chemoradiotherapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Taken", "together", ",", "these",...
PMC11739504	Nuclei were stained with DAPI (blue).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Nuclei", "were", "stained", "with", "DAPI", "(", "blue", ")", "." ] } ]
PMC11701801	In this study, we clarified that the cBAF subcomplex is deficient in the SWI/SNF complex, resulting in dependency on the CBP/p300 paralog pair.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11708541	C] methoxy-4-aminopyridine ([C]3MeO4-AP) 73 and [F], ([F]3F4-AP) 71, two similar tracers, are less common than [C] with slower kinetics and lower initial brain absorption.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11257988	KRAS, in its active state, binds to GTP and has an intrinsic enzymatic activity to cleave the terminal phosphate of nucleotides, converting it to GDP.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Results: Between January 2020- February 2022, 75 patients with HN and COVID19 infection were identified.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "Between", "January", "2020-", ...

PMC10551595

Cell apoptosis rate was determined using the BioLegend kit (BioLegend).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "apoptosis", "rate", "was", "determined", "using", "the", "BioLegend", "k...

PMC6889484

Average of two independent infections per ratio is indicated.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Average", "of", "two", "independent", "infections", "per", "ratio", "is", "indicated", "." ] } ]

PMC11615743

Validation of L‐DNA device for target cell labeling via a dual‐aptamer‐based logic gate.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Validation", "of", "L‐DNA", "device", "for", "target", "cell", "labeling", ...

PMC10362265

The best structure was selected based on the discrete optimized protein energy score .

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PMC9918897

Xanthohumol administered to mice orally in a water–alcohol-based matrix did not have a direct protective effect on tumor growth (induced by the injection of HeLa tumorigenic cell lines) and did not have a positive effect on plasma antioxidant capacity either.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11721587

The luciferase activity was determined using dual-luciferase reporter assay system (Promega) and FLUOstar OPTIMA (BMG Labtech).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "luciferase", "activit...

PMC8524093

Although CHIKF is known as a non-deadly disease, atypical and severe acute manifestations can evolve to multiple organ failure and death.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Although", "...

PMC11402217

The stagnation in developing new treatments for metastatic OS over the last thirty years has stalled clinical advancements, underlining the critical need for more effective, targeted therapies.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

A greater proportion of M1 macrophages were present in patients with GCB compared to ABC COO subtype (Kruskal Wallis chi-squared 7.66, p value <0.01).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11564405

A total of 140 patients who had been diagnosed with primary NSCLC (including 66 lung adenocarcinomas and 74 lung squamous cell carcinomas) were enrolled in our study.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11699465

Trucked TMEM199 sequences were amplified and assembled into the expression vectors with Flags.

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PMC8409415

Among 63 OvCA surgical specimens, there were 29 women who received NACT before cytoreductive surgery.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Among", "63", "OvCA", "surgical", "specimens", ",", ...

PMC11509278

Ethanol (70%) extract of Cuban red propolis exhibited antiproliferative and cytotoxic effects on MDA MB-231 cells, probably related to PI3K/Akt and ERK1/2 pathways .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "...

PMC9429973

The anti-HTN drugs were categorized as follows: 1) Angiotensin-converting-enzyme inhibitors and Angiotensin receptor blockers (ACEi/ARB); 2) Beta-blockers (BB); 3) Calcium channel blockers (CCB); 4) Hydrochlorothiazide (HCTZ) and 5) non-HCTZ diuretics (other-DU).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC6901583

This work showed the involvement of this pathway in the increased expression of CCL2 induced by BRD4.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "work", "showed", "the", "involvement", ...

PMC10747160

A total of 20 μg mL of mannan also appears to efficiently prevent all strains’ trans-infection, thereby demonstrating that the presence of additional structural proteins does not impair DC-SIGN’s ability to bind to viral surface glycoproteins and facilitate trans-infection (Figure 7D,E and Figure S10).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9895440

This procedure was repeated (with IL-2 stimulation at each stimulation) according to the scheme in Supplementary Fig. 1a.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "procedure", "was", ...

PMC8567602

This model is supported by the observation that proteasome inhibition blunts CBAF-specific component reductions in the presence of the fusion (Fig. 7H and I).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC10291556

This suggests that the presence of the ethylenediamine linker, if it remains attached to DCF, does not qualitatively affect the resulting biological properties.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC11301095

Fig. 1Brain MRI images.

[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "1Brain", "MRI", "images", "." ] } ]

PMC10197932

These cytokines are important for the survival and proliferation of naïve T and mainly cytotoxic cells 46.

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PMC10759659

Overall, 425 HBV-related hepatocellular carcinoma patients were enrolled in the study.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Overall", ",", "425", "HBV-related", "hepatocellular", "carcinoma", "patients", "were"...

PMC5535901

Indole-3-carbinol (I3C) and its dimer diindolylmethane (DIM) are bioactive metabolites of a glucosinolate, glucobrassicin, found in cruciferous vegetables.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC10877303

Fig. 8 The binding-free energy of the top three drugs and inhibitor complexes calculated by the MM-PBSA method.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "8", "The", "binding-free", "en...

PMC11769516

These substances were evaluated for their chemical composition and found to contain polyphenols, which indicated their potential in the treatment of mycotoxin poisoning.

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PMC9583612

This verification must go beyond satisfying a checklist of operator actions but involve academic experts who can provide an independent evaluation of all relevant data.

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PMC11740207

These findings suggest that HL60 retains a hierarchical structure similar to that observed in vivo, with distinct subpopulations contributing to disease progression and treatment resistance.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC9429973

The tolerability profile of the combination regimens was manageable, with no unexpected safety concerns.

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PMC10812665

For such compounds, information spanning from molecular target interaction to in vivo adverse outcomes is available.

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PMC11694066

All animal procedures and studies were performed in accordance with the approved guidelines for animal experimentation by the Ethics Committee at the Université Paris-Sud (CEEA 26, project 2014_055_2790) following EU regulation.

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PMC11706776

Further studies are needed to identify the calcium channel components (such as the Orai and TRP families) associated with SK1 in ES cell.

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PMC10452486

Each alpha and beta chain comprises groove (G-ALPHA [D1] and G-BETA [D1]) and constant (C-like ALPHA [D2] and C-like BETA [D2]) domains .

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PMC10808409

The larger the coefficient, the more the influence of that factor on the studied response.

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PMC11476837

Under homeostatic conditions, NRF2 is maintained at low levels in the cytosol through its interaction with KEAP1, which directs NRF2 toward proteasome.

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PMC11348300

The mice were housed in the Dartmouth central animal facility and fed special diet—MP biomedical purified diet.

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PMC10040136

In summary, this study points to the capability of MSC to promote GIST resistance in targeted therapies.

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PMC11290772

Remarkably, the findings of this investigation underscored the remarkable efficacy of ROBO1-NK cells in selectively eliminating tumor cells and organoids.

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PMC11525028

The antibodies for western blot assay were provided in Table S11.

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PMC11594641

MITF is known to regulate the expression of late endosomal proteins.

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PMC10914904

Some svtRNAs can be loaded into AGO2, regulating posttranscriptional gene silencing It has been reported that vtRNA1-1 may not undergo cleavage by DICER .

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PMC10975211

Understanding these natural peptides holds significant potential for developing effective and targeted therapies against cancer and infectious diseases.

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PMC11738017

In the recently reported trial with linvoseltamab at sBCMA levels ≥ 400 ng/mL, a 200-mg TCE dose significantly improved the overall response when compared with a dose of 50 mg.

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PMC9429973

Image: Summary/Conclusion: Our cohort confirms that BNS may present with leptomeningeal disease and/or parenchymal disease, de novo and without systemic disease.

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PMC11774112

The calculated IC50 in the PHRD-DTIC and PHRD- miRNA 34a was lower than free DTIC and free miRNA 34a groups at 72 h (2.609 ± 2.425 µg/mL vs 6.287 ± 4.106 µg/mL; 1.81 ± 5.13 µg/mL vs 1.894 ± 4.627 µg/mL, respectively).

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PMC10812665

The procedure was used as detailed earlier .

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PMC9325715

FTIR analysis was performed for both native bLTF and modified with Fe in the MIR range (4000–400 cm).

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PMC8978939

Protein residues were treated using the AMBER ff14SB force field.

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PMC10203589

In the process of exploring FGF18 and non-coding RNA mediated HCC progression.

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PMC11269792

The above-mentioned reporter gene vector, along with miR-6838-5p mimic or mimic NC was co-transfected into GIST-882 cells (5×10) in the 24-well plates using Lipofectamine 2000 (Invitrogen).

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PMC9964654

Water led to the micelle formulation AS4 standing out as the one with the highest [Au(cdc)2] loading content (LC (mg[Au(cdc)2]−/gBCM) = 5.68).

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PMC11085211

IC50 was instead calculated with the free “aatbioquest” tool (https://www.aatbio.com/tools/ic50-calculator, accessed on 11 April 2024).

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PMC11684821

The bias toward TRAJ42 use and conservation of a semi-invariant motif makes it tempting to speculate that the cells we describe across multiple donors likely exhibit limited antigen diversity and might bind to an identical MR1-bound cargo at the cancer cell surface.

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PMC10135767

When lymphocytes are recruited to inflammatory regions, cytoplasmic Ca acts as a signaling molecule to facilitate the transformation of the cell state from rolling to arrest to achieve functional activation .

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PMC11186948

The subject and its family gave informed consent.

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PMC11248911

The formed precipitate was filtered, washed with water and dried to give the corresponding thiazolidinone derivatives.

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PMC7154001

The title and abstract of each article search from PubMed (via Endnote) and ScienceDirect databases using the keywords mentioned above were initially screened for relevant original articles based on the inclusion and exclusion criteria.

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PMC9424261

Next, we examined whether HERPUD1 played a vital role in increasing the sensitivity of liver cancer cells to ferroptosis following CA treatment.

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PMC11424574

The shLuc- and shMTA2-osteosarcoma cells (1×10/well) were seeded in 6-well plate and incubated for 7 days, then stained with crystal violet reagent (1:20) for 30 mins.

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PMC11473843

To establish an in vitro model mimicking FAK inhibitor resistance in NSCLC, we treated A549 cells with increasing doses of VS-4718, which resulted in the enrichment of drug-resistant cells that were characterized by slow proliferation and a mesenchymal-like morphology (Fig. 5A,B).

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PMC11225860

This cell progresses through G1 but fails entry into S/G2 (Fig. 5c and Sup Fig. 5c).

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PMC11792766

Cells were subcultured under sterile conditions to 80%–90% confluence at 37°C and 5% CO2 and detached using 0.25% v/v trypsin‐EDTA phenol red solution.

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PMC4369959

Ginger extract not only inhibits carcinogenesis of colorectal cancer cells but also enhances the anticancer effects of chemotherapeutic drug 5-fluorouracil.

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PMC11459296

We evaluated the functionality of the transplanted human immune cells both ex vivo and in vivo.

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PMC11770199

Therefore, we next construed the engineered MSCs carrying a coding gene of p14 protein (MSCs-p14) and tested their antitumor therapeutic effect in vitro and in vivo.

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PMC11190062

BCMA is a target for CAR T cells and bispecific antibodies approved to treat MM patients (36).

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PMC11248911

Anal.

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PMC11337594

A375 cells were treated with TER (2 µg/ml) for 24 h, and the images show the distribution of Ki67 (red) protein. (

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PMC11535726

Conidia 30–55 × 9–13.5 μm (x̄ = 40 × 11.1 µm, n = 30), solitary, acrogenous, cylindrical, oblong and occasionally clavate, smooth, guttulate, 2–4-septate, slightly or deeply constricted and darker at the septa, brown, rounded at the apex and sometimes truncate at the base, exhibiting obtuse ends.

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PMC11258145

Due to the fact that the use of curcumin in liposomal form is becoming more and more common, the concentration of this compound, in cells can reach much higher level, definitely exceeding the amounts that can enter the body when applied in natural form.

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PMC11429241

The 3D cell cultures without the scaffold were made following protocol , and 14,000 cells were seeded per well.

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PMC9985266

In conclusion, our study shows that IL-27 upregulates MEG3 expression through inhibition of DNMT1-mediated lncRNA MEG3 promoter methylation, which in turn inhibits ERK/p38 signaling pathway-induced autophagy and attenuates BLM-induced PF, providing a contribution to the elucidation of the potential mechanisms by which ...

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PMC11323699

However, after informed consent from participating patients, paired formalin-fixed, paraffin-embedded (FFPE) tumor samples were obtained at diagnosis and after 3 cycles of NACT in order to study changes in iTME during NACT.

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PMC11185260

In comparison, the body weight of mice receiving scL-SMARCB1 treatment remained stable for an extended period before rapidly decreasing as the tumor burden increased.

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PMC9512971

From these data, we therefore considered it was possible to demonstrate the superiority of camostat mesilate over placebo with a sample size of 100 patients (50 patients per group).

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PMC11543935

B: HE staining of untreated control with homogenic staining of the ECM.

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PMC11700247

Data represent irradiated tumors from the fractionated- or single-dose–treated groups. (

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PMC11349530

Conditioned media derived from lung cancer cells induced pro-tumoral phenotypes in macrophages (15).

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PMC7189327

However, the influence of these two genes on BCC pathogenesis has not been fully investigated.

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PMC11468365

The value ranges from 0 to 1, where 0 indicates a poor prediction model and 1 indicates a perfect prediction model.

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PMC11569208

Fluorescent foci were counted 24 h post infection (hpi) and expressed as fold-change over the infected-only condition (n = 3, mean). (

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PMC9429973

To estimate the penetrance of NMs associated with pathogenic germline variants, we calculated cumulative incidence of MN in a cohort of 384 first-degree relatives (kin-cohort) of DDX41-mutated NM cases.

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PMC11257988

MicroRNAs (miRNAs) are another important class of non-coding RNAs that play a role in gene regulation by degrading mRNA or inhibiting translation.

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PMC10094712

Origin v8.5 (Microcal Software Inc., Northampton, MA, USA) and Prism 5 (GraphPad Software, La Jolla, CA, USA) were used for plotting the data and statistical processing.

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PMC11655498

In contrast, EBV miR-BHRF1-2-5p, miR-BART2-5p, and the host miR-17-5p have been shown to weaken the BCR-mediated reactivation of EBV in vivo (Chen et al., 2019).

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PMC9429973

For pZAP70 mean RFI in CD4+ cells was 8.8 in controls compared with 2.2 in rux patients (p=0.05).

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PMC11782508

d-f) Cell cycle analysis by propidium iodide staining. (

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PMC11615101

Briefly, 100µl of plasma sample was added to the pre-coated ELISA plate (provided) along with the standard and incubated for 120min at 37°C.

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PMC10900886

Human rhabdomyosarcoma (RD) cells were cultured in DMEM (Lonza) supplemented with 10% FBS and PSG.

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PMC10808409

Q1: shows necrotic cells, Q2: shows later period apoptotic cells, Q3: shows normal cells, Q4: shows early apoptotic cells. (

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PMC7192625

Comprehensive epigenomic data was collected for neutrophils, including four histone modifications, DNA methylation and expression levels across all individuals, allowing us to test the robustness of our findings in this cell type.

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PMC10040136

1Proportion of MSC in clinical samples correlates with Imatinib resistance and prognosis.

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PMC11045125

Consistent with this possibility, we found that the one ΔEBNA2 + Myc tumor-derived cell line (“R3”) that constitutively expresses LMP1 when grown off the CD40L/IL21 expressing feeder cell layer also has a much higher level of total STAT3, phosphorylated STAT3, and Src in comparison to the other cell lines that do not e...

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PMC10452486

Notably, these two categories differed in their glycosylation (mannose residues), density, and location on the cell surface.

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PMC11742670

Among them, the simplest and cheapest ones were prioritized for the next WET LAB phase.

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PMC11185260

Taken together, these results indicate that combining radiation with scL-SMARCB1 is more effective and safer than conventional chemoradiotherapy.

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PMC11739504

Nuclei were stained with DAPI (blue).

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PMC11701801

In this study, we clarified that the cBAF subcomplex is deficient in the SWI/SNF complex, resulting in dependency on the CBP/p300 paralog pair.

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PMC11708541

C] methoxy-4-aminopyridine ([C]3MeO4-AP) 73 and [F], ([F]3F4-AP) 71, two similar tracers, are less common than [C] with slower kinetics and lower initial brain absorption.

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PMC11257988

KRAS, in its active state, binds to GTP and has an intrinsic enzymatic activity to cleave the terminal phosphate of nucleotides, converting it to GDP.

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