OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11291697	A combination of high-resolution array-CGH (1 M platform) and qPCR analysis allowed to refine the deletion boundaries between chromosomal positions (hg38) chr2:144,119,297 (Proximal 1 probe) and chr2:144,194,675 (Distal 3 probe) (Fig. 1A and Supplementary Table S1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9910796	Bars, 100 nm. (	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Bars", ",", "100", "nm", ".", "(" ] } ]
PMC9429973	Aims: Here we aim to study different clinicopathologic and genetic parameters that affect the disease course in PMF patients along with their treatment history and disease outcome, in order to find out the most significant factor/s.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11730320	The PTCRA variant described here was missed by a clinical panel and WES but trio WGS revealed a homozygous 8kb deletion.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "PTCRA...
PMC6181431	VHL mutations were seen in all 5 ccRCCs, as expected.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "VHL", "mutations", "were", "seen", "in", "all", "5", "ccRCCs", ",", "as", "expe...
PMC11796104	The clinical validation results are consistent with predictions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "clinical", "validation", "results", "are", "consistent", "with", "predictions", "." ] } ]
PMC9429973	The d-dimers were 3393microg/L. Factor VIII level was 0.7% and the Bethesda assay confirmed inhibitor titer of 10.2 BU.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "d-dimers", "were", ...
PMC9118379	In this study, trypsin was considered the protease for digestion.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "this", "study", ",", "trypsin", "was", "considered", "the", "protease", "for", ...
PMC11033180	All protocols were carried out in accordance with French standard ethical guidelines for laboratory animals (Agreement # 02476.01).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "protocols", "were", ...
PMC9429973	Methods: Eligible randomized controlled trials published before Dec 2021 were retrieved from databases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Methods", ":", "Eligible", "randomized", "controlled", "trials", "publ...
PMC11188874	Error bars indicate the SD of the mean.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Error", "bars", "indicate", "the", "SD", "of", "the", "mean", "." ] } ]
PMC11545737	Pyroptosis in the gastric mucosa of H. pylori-infected subjects has been associated with the transition from chronic gastritis to gastric cancer, which has been found to be promoted by CagA .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11243198	The pyrrolidine ring of BAS 07019774 could also be opened or modified without negatively impacting any of the interactions suggested in this work.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC10237474	The development of a HEK293S mutant cell line lacking the enzyme N-acetylglucosaminyl-transferase I (GnTI) inhibits the formation of complex sugars .	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC11767725	A small study found that MetS was present in 35.2% of patients with seborrheic dermatitis (SD) compared to 10.6% of the control group .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11047729	The direct effect of this substance on telomerase is yet to be established, but it has been reported that it has an antitumor and growth-inhibitory effect.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11543853	Therefore, the cells in our cryo-ET experiments were infected with a multiplicity of infection of 29.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "the", "cells", "in", "our...
PMC11730000	It demonstrates diverse biological activities, including antioxidative, anti-inflammatory, antimutagenic, antiangiogenic, antiapoptotic, and antifibrotic properties.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "demonstrates", "divers...
PMC9429973	Patients with at least a minor response to VRd or KRd transitioned to IRd.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "with", "at", "least", "a", "minor", "response", "to"...
PMC11740207	Studies have demonstrated that MIAMICs can maintain a quiescent phase with minimal expression of cell cycle markers, much like LT-HSCs, which also remain inactive for extended periods (D’Ippolito et al., 2004).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The 1-year PFS and OS were 83.3% and 93.5%, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "1-year", "PFS", "and", "OS", "were", "83.3", "%", "and", ...
PMC7961460	Concerning the tumour microenvironment, several molecules such as matrix metalloproteinases, growth factors, interleukins, chemokines, collagen and proteoglycans have been recognized as participants to the tumour-stromal interplay.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11473750	We utilized public data resources produced by the Cancer Cell Line Encyclopedia (CCLE) and Project Achilles via the Cancer Dependency Map portal (DepMap, 20Q1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC9429973	Aims: Evaluate overall survival in patients with acute leukemia and COVID-19 infection.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "Evaluate", "overall", "survival", "in", "patients", "with", ...
PMC10440586	R represents the Pearson correlation coefficient. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "R", "represents", "the", "Pearson", "correlation", "coefficient", ".", "(" ] } ]
PMC11765243	Intriguingly, unlike mature T cells, we showed that early activation of Erk and Akt was enhanced in thymocytes from p110αKD-T mice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Intrigu...
PMC9509578	Their results showed efficient drug accumulation, inhibition of efflux pumps via MRP1 gene expression and induction of cell death mechanisms in human lung cancer H69AR cells, MCF-7/AD breast cancer cells, HCT15 colon cancer cells and A2780/AD ovarian cancer cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", ...
PMC10452486	These variants may serve as biomarkers of disease.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "variants", "may", "serve", "as", "biomarkers", "of", "disease", "." ] } ]
PMC11126803	This article contains supporting information.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "article", "contains", "supporting", "information", "." ] } ]
PMC11621493	Data are shown as mean ± SD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "shown", "as", "mean", "±", "SD", "." ] } ]
PMC11543935	Figure 1B illustrates the cable duct which allows the fiber optic sensor to access the ablation area, while a positioning support ensures a parallel placement of the electrode with a fixed penetration depth.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	In pts with mastocytosis, it recommended prophylaxis with antihistamines from the day prior to the vaccination to 5 days after, and an observation of 60 min after the vaccination.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9046263	Therefore, utilizing patient-derived glioma stem-like cells offers a potential option for uncovering novel HERV transcripts in gliomas.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "utilizing", "patient-deriv...
PMC11592837	Additionally, we showed formerly unknown drug-specific differences to timely induce DNA and cell damage.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "we", "showed", "formerly", "unknown", ...
PMC9429973	Aims: We aimed to functionally characterize multiple previously uncharacterized variants of CXCR4 using in vitro assays.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "We", "aimed", "to", "functiona...
PMC11387401	The other HIV-1 proteins displayed a more limited host RNA binding profile with less than 50 interactions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "other", "HIV-1", "proteins", "displayed", ...
PMC2196094	The filters were hybridized with a P-labeled probe consisting of a purified cDNA fragment from the RMCP-8 clone.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "filters", "were", "hybridized", ...
PMC9429973	Response was assessed by an independent review committee.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Response", "was", "assessed", "by", "an", "independent", "review", "committee", "." ] } ]
PMC11506670	Here, the three novel NRAS mutations—c.142G>T (G48C), c.127C>A (Q43K), and c.109G>A (E37K)—were characterized for their effects on cancer phenotypes in vitro, using NIH3T3 and HCT116 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Patients described disease characteristics as worsening (much worse or somewhat worse) since their diagnosis, including chronic pain (66%), kidney disease (55%), and acute pain (48%) (Figure).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	All are evaluable for DLT.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "are", "evaluable", "for", "DLT", "." ] } ]
PMC7685376	According to global cancer statistics from Globocan, there were 841,080 cases of liver cancer worldwide (HCC accounted for 85%) in 2018, accounting for 4.7% of the total cancer incidence in the same period.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11536589	Control mice (MGST1 KO) were administered vehicle at the same time points.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Control", "mice", "(", "MGST1", "KO", ")", "were", "administered...
PMC6337547	Finally, it is catalysed by CYP98A14 to rosmarinic acid .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Finally", ",", "it", "is", "catalysed", "by", "CYP98A14", "to", "rosmarinic", "acid", "." ...
PMC11406030	Univariable analysis of the prognostic effect of nuclear and cytoplasmic LMTK3 on overall survival within 10 years from diagnosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Univariable", "analysis", "of", "...
PMC11650848	average methylation between 6 CpG sites measured by pyrosequencing, SD standard deviation, min minimum, max maximum, N number of samples, significance indicated by p < 0.05 and is measured by ANOVA between the genotypes We also confirmed these findings using the previously reported SNP rs2747429, which is 21 base pairs...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Eight BM AML samples were purchased from Analytical Biological Services and 11 BM samples were obtained at the screening from evaluable patients with relapsed/refractory AML enrolled in CA-4948-102 clinical trial.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11367146	Fig. 14Effect of VTE on changes in phosphorylation of (A) ERK2 (B) p38 (C) JNK and (D) STAT3 in IL-1β stimulated SW982 cell by ELISA test.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7338939	Recently, Norihiko Saito and colleagues have reported that GSI resistance results from a change in oncogene addiction, from NOTCH to constitutive AKT in glioblastoma, and that the combination of GSIs and PI3K inhibitors may reduce tumor growth in glioblastoma (51).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11388384	Cells were washed 3x in PBS and incubated at 4 °C overnight prior to imaging.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "washed", "3x", "in", "PBS", "an...
PMC9429973	Image: Summary/Conclusion: Pts in the crizanlizumab MAP had significant disease burden at baseline, as evidenced by the high rate of home- and healthcare-managed VOCs, proportion of patients with SCD-related complications and use of opioids for VOC-related pain relief, despite many pts reporting prior HU use.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10968586	OLE and HT may also magnify the efficacy of other types of cancer treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "OLE", "and", "HT", "may", "also", "magnify", "the", "efficacy", ...
PMC11394730	QUE has chemopreventive effects at low concentrations because it acts as an antioxidant; however, at high concentrations, it acts as a pro-oxidant and may have chemotherapeutic effects .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2196094	Clones showing positive hybridization signals with the PCR primer but were negative with the RMCP-2-specific probe were selected for further analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Clones", "showing", ...
PMC11534377	Efficacy monitoring was achieved using recurrent IVIS Imaging, concluding in terminal macroscopic metastatic analysis post-euthanasia after 32 days.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Efficacy", "monitoring", "was", "...
PMC11756514	The ability of the HEK293-Langerin, HEK293-MGL, or HEK293-empty vector cell lines to bind neoglycoproteins was examined using neoglycoproteins having ~20 monosaccharides coupled per BSA molecule (according to the manufacturer).	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC11400680	Further enhancement can be achieved by augmenting the prompt generator to increase its generalizability specifically for nucleus segmentation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Further", "enhancement", "can", "be", ...
PMC9509578	Stimuli-responsive nanosystems take advantage of unique cellular properties including pH variation, redox potential as well as enzymatic activation to overcome the MDR phenomena.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	If not available, CCP or PFC can be used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "If", "not", "available", ",", "CCP", "or", "PFC", "can", "be", "used", "." ] } ]
PMC11474209	In addition, utilities should explore methods to limit the entry of cells into the plant or implement steps to address possible cyanotoxins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC9429973	Based on these findings, we developed expanded CMPs (exCMPs) that leverage the spleen environment to improve early hematopoietic recovery after transplantation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11628904	For infection experiments, zebrafish larvae were exposed to C. albicans diluted in E3 medium without methylene blue to a final concentration of 1 × 10 cells/mL beginning immediately after burn wounding.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11129910	The possibility of tumor suppressor genes on the X chromosome was raised a few years ago, and studies suggested that the loci on the X chromosome carry tumor suppressor genes .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11389534	However, neither UFM1 nor DDRGK1 is required for insulin release mediated by glucose.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "neither", "UFM1", "nor", "DDRGK1", "is", "requir...
PMC8524093	Indeed, infection of these cells is a key step for stablishing the disease since CHIKV titer is rapidly increased, which is essential to reach other targets without being completely neutralized by host immune system.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11777207	Alternatively, avelumab’s binding affinity to PD-L1 is approximately 10-fold stronger with a Kd = 0.0467 nM, a critical distinction in binding kinetics compared to avelumab and durvalumab (36).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10490530	Recently, many bioluminescence mushroom species have been reported which are evolutionarily divergent from other known terrestrial or marine species .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Recently", ",", "many", ...
PMC11774251	Immunoblotting of K1, K6 and K17 in HaCaT cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Immunoblotting", "of", "K1", ",", "K6", "and", "K17", "in", "HaCaT", "cells", "."...
PMC8735881	Effects of CMI constructs on the surface expression of CD4, CCR5, and CXCR4 in transduced TZM-bl cells were detected by FACS analysis using a PE-conjugated anti-human CD4, CCR5, or CXCR4 antibody and judged by fluorescence intensity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11291490	DEFs were subjected to transfection with either pVAX-TPA (control) or pVAX-TPA-dusCD40L (dusCD40L) using TransIntroTM EL Transfection Reagent (TransGen Biotech, China) as per the manufacturer’s instructions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11532793	We evaluated the computational performance of bootstrap and Gibbs sampling algorithms during transcript quantification with Salmon using our simulated RNA-seq experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "evaluated", ...
PMC9429973	Results: As of data cutoff on 5 May 2021, 65 treated pts had at least 4 months of follow-up on or after study drug treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10578720	The endpoint was set at 10 weeks from treatment initiation. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "endpoint", "was", "set", "at", "10", "weeks", "from", "treatment", "initiation...
PMC10522430	A suspension of 400 L binding buffer incorporating 5 L annexin V-FITC and 10 L PI was prepared, and a 10-minute incubation at 4°C in darkness ensued.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	To decipher the underlying molecular pathomechanism, we defined the molecular partners of RhoG in human lymphocytes and discovered that RhoG interacts with the regulator of cytotoxic granule (CG) release Munc13-4 inducing docking of Munc13-4-positive CGs to the plasma membrane.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3888431	Our reference-based pipeline predicted 5,636 new putative gene loci in addition to the 24,238 gene loci predicted by Xu et al. (Figure 8a), extending the total set of putative gene loci in the CHO-K1 genome to 28,596.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10197932	At 2T treatment, Jurkat cells do not show necrotic effect as AML cell lines (Figure 2A).	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "2", "T", ...
PMC9592219	TOP2A promotes tumor progression through the Hippo pathway.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TOP2A", "promotes", "tumor", "progression", "through", "the", "Hippo", "pathway", "." ] } ]
PMC10114490	These cells can be maintained in fibroblast culture media, under standard cell culture conditions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "cells", "can", "be", "maintained", "in", "fibrobla...
PMC11730320	This was not primarily due to an increase in the dominant circulating γδ+ T cell population (typically Vγ9δ2), but rather, emergence of a large population determined to be 75% Vδ1+, with the remainder Vδ1-Vδ2- (Fig. 5A, B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11539788	Finally, the samples were subjected to immunoblotting to detect ubiquitin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Finally", ",", "the", "samples", "were", "subjected", "to", "immunoblotting", "to", "...
PMC6889484	Figure 4Absence of Selection for NL4-3 Variants that Can Replicate in CEM/D128K Cells(A) NL4-3 virus was used to infect different ratios of CEM:CEM/D128K cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11621565	Mono-colonization with curli-producing Escherichia coli worsened motor impairments and gastrointestinal issues in α-synuclein-overexpressing mice, enhancing α-synuclein aggregation and inflammation in the gut and brain.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9509578	A liposomal nanoformulation was the first clinically approved nanosystem for anticancer drug delivery .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "liposomal", "nanoformulation", "was", "the", "first", "clinically", "a...
PMC10482220	G3BP oligomerization in vitro. (	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "G3BP", "oligomerization", "in", "vitro", ".", "(" ] } ]
PMC9960565	For metallodendrimers’ hemotoxicity assessment, 10% (v/v) of a blood solution was prepared in PBS (Mg/Ca free).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", ...
PMC11774251	Statistical significance is indicated as P <0.05, P <0.01, P <0.001, **P <0.0001, ns = not significant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11794568	Real-time quantitative polymerase chain reaction (RT-qPCR) and Western blots (WB) were used to detect stable overexpression and knockdown of CRIP1 in melanoma cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6450504	For flow cytometry analysis, spheroids were washed twice with PBS and dispersed into single cells by 10 min incubation with AccuMax cell detachment/disassociation solution at 37 °C (Sarisozen et al., 2016).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11754784	Source data are provided as a Source Data file.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Source", "data", "are", "provided", "as", "a", "Source", "Data", "file", "." ] } ]
PMC11528603	In the cytoplasm, the formation of APAF1 complex with other proteins resulted in apoptosome that activates pro-caspase 9.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "cytoplasm", ",", ...
PMC11534035	As the concentration of G1 was increased to 2.5 and 5 μM, the reduction in tumor sphere size became significant (2.5 μM: M=9,478±2,481 px vs. control; p<0.0001; 5 μM: M=10,931±1,815 px vs. control; p<0.001).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2196094	To minimize potential misunderstandings upon comparisons of mouse and rat MC proteases we have suggested a nomenclature which as close as possible harmonises between the corresponding proteases in these two species.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The kinetics and function of CAR-T cells was monitored by quantitative PCR and flow cytometry.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "kinetics", "and", "function", "of", "CAR-T", "cells"...
PMC9429973	Methods: Retrospective data analysis of all pediatric patients diagnosed with (VWD) throughout a period of 10 years, dating from January 2012 till December 2021.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10376064	Twenty mg of homogenate was mixed with 10 µL cold Tris-buffered saline (TBS, pH 7.5, containing protease inhibitor (Roche, Germany)) per 1 mg brain.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11748335	We monitored the number of peaks in LOCKs and typical peaks, finding that a WScutoff of approximately −0.7 yielded a stable count of both types of peaks (Fig. S1A-B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11590870	The effect of the first two doses was not statistically different from that of the negative control.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "effect", "of", "the", "first", "two"...
PMC11704135	These derivatives possess the ability to scavenge reactive oxygen species (ROS) and inhibit oxidative damage to cellular components.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "derivatives", "poss...
PMC10198699	Specificatio would not be applicable (as the research institution is not acting in good faith) and the present-day Henrietta Lacks would automatically be the owner of the cell line derived from her tissue sample.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11291697

A combination of high-resolution array-CGH (1 M platform) and qPCR analysis allowed to refine the deletion boundaries between chromosomal positions (hg38) chr2:144,119,297 (Proximal 1 probe) and chr2:144,194,675 (Distal 3 probe) (Fig. 1A and Supplementary Table S1).

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PMC9910796

Bars, 100 nm. (

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PMC9429973

Aims: Here we aim to study different clinicopathologic and genetic parameters that affect the disease course in PMF patients along with their treatment history and disease outcome, in order to find out the most significant factor/s.

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PMC11730320

The PTCRA variant described here was missed by a clinical panel and WES but trio WGS revealed a homozygous 8kb deletion.

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PMC6181431

VHL mutations were seen in all 5 ccRCCs, as expected.

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PMC11796104

The clinical validation results are consistent with predictions.

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PMC9429973

The d-dimers were 3393microg/L. Factor VIII level was 0.7% and the Bethesda assay confirmed inhibitor titer of 10.2 BU.

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PMC9118379

In this study, trypsin was considered the protease for digestion.

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PMC11033180

All protocols were carried out in accordance with French standard ethical guidelines for laboratory animals (Agreement # 02476.01).

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PMC9429973

Methods: Eligible randomized controlled trials published before Dec 2021 were retrieved from databases.

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PMC11188874

Error bars indicate the SD of the mean.

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PMC11545737

Pyroptosis in the gastric mucosa of H. pylori-infected subjects has been associated with the transition from chronic gastritis to gastric cancer, which has been found to be promoted by CagA .

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PMC11243198

The pyrrolidine ring of BAS 07019774 could also be opened or modified without negatively impacting any of the interactions suggested in this work.

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PMC10237474

The development of a HEK293S mutant cell line lacking the enzyme N-acetylglucosaminyl-transferase I (GnTI) inhibits the formation of complex sugars .

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PMC11767725

A small study found that MetS was present in 35.2% of patients with seborrheic dermatitis (SD) compared to 10.6% of the control group .

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PMC11047729

The direct effect of this substance on telomerase is yet to be established, but it has been reported that it has an antitumor and growth-inhibitory effect.

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PMC11543853

Therefore, the cells in our cryo-ET experiments were infected with a multiplicity of infection of 29.

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PMC11730000

It demonstrates diverse biological activities, including antioxidative, anti-inflammatory, antimutagenic, antiangiogenic, antiapoptotic, and antifibrotic properties.

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PMC9429973

Patients with at least a minor response to VRd or KRd transitioned to IRd.

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PMC11740207

Studies have demonstrated that MIAMICs can maintain a quiescent phase with minimal expression of cell cycle markers, much like LT-HSCs, which also remain inactive for extended periods (D’Ippolito et al., 2004).

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PMC9429973

The 1-year PFS and OS were 83.3% and 93.5%, respectively.

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PMC7961460

Concerning the tumour microenvironment, several molecules such as matrix metalloproteinases, growth factors, interleukins, chemokines, collagen and proteoglycans have been recognized as participants to the tumour-stromal interplay.

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PMC11473750

We utilized public data resources produced by the Cancer Cell Line Encyclopedia (CCLE) and Project Achilles via the Cancer Dependency Map portal (DepMap, 20Q1).

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PMC9429973

Aims: Evaluate overall survival in patients with acute leukemia and COVID-19 infection.

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PMC10440586

R represents the Pearson correlation coefficient. (

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PMC11765243

Intriguingly, unlike mature T cells, we showed that early activation of Erk and Akt was enhanced in thymocytes from p110αKD-T mice.

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PMC9509578

Their results showed efficient drug accumulation, inhibition of efflux pumps via MRP1 gene expression and induction of cell death mechanisms in human lung cancer H69AR cells, MCF-7/AD breast cancer cells, HCT15 colon cancer cells and A2780/AD ovarian cancer cells .

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PMC10452486

These variants may serve as biomarkers of disease.

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PMC11126803

This article contains supporting information.

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PMC11621493

Data are shown as mean ± SD.

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PMC11543935

Figure 1B illustrates the cable duct which allows the fiber optic sensor to access the ablation area, while a positioning support ensures a parallel placement of the electrode with a fixed penetration depth.

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PMC9429973

In pts with mastocytosis, it recommended prophylaxis with antihistamines from the day prior to the vaccination to 5 days after, and an observation of 60 min after the vaccination.

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PMC9046263

Therefore, utilizing patient-derived glioma stem-like cells offers a potential option for uncovering novel HERV transcripts in gliomas.

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PMC11592837

Additionally, we showed formerly unknown drug-specific differences to timely induce DNA and cell damage.

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PMC9429973

Aims: We aimed to functionally characterize multiple previously uncharacterized variants of CXCR4 using in vitro assays.

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PMC11387401

The other HIV-1 proteins displayed a more limited host RNA binding profile with less than 50 interactions.

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PMC2196094

The filters were hybridized with a P-labeled probe consisting of a purified cDNA fragment from the RMCP-8 clone.

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PMC9429973

Response was assessed by an independent review committee.

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PMC11506670

Here, the three novel NRAS mutations—c.142G>T (G48C), c.127C>A (Q43K), and c.109G>A (E37K)—were characterized for their effects on cancer phenotypes in vitro, using NIH3T3 and HCT116 cells.

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PMC9429973

Patients described disease characteristics as worsening (much worse or somewhat worse) since their diagnosis, including chronic pain (66%), kidney disease (55%), and acute pain (48%) (Figure).

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PMC9429973

All are evaluable for DLT.

[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "are", "evaluable", "for", "DLT", "." ] } ]

PMC7685376

According to global cancer statistics from Globocan, there were 841,080 cases of liver cancer worldwide (HCC accounted for 85%) in 2018, accounting for 4.7% of the total cancer incidence in the same period.

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PMC11536589

Control mice (MGST1 KO) were administered vehicle at the same time points.

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PMC6337547

Finally, it is catalysed by CYP98A14 to rosmarinic acid .

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PMC11406030

Univariable analysis of the prognostic effect of nuclear and cytoplasmic LMTK3 on overall survival within 10 years from diagnosis.

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PMC11650848

average methylation between 6 CpG sites measured by pyrosequencing, SD standard deviation, min minimum, max maximum, N number of samples, significance indicated by p < 0.05 and is measured by ANOVA between the genotypes We also confirmed these findings using the previously reported SNP rs2747429, which is 21 base pairs...

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PMC9429973

Eight BM AML samples were purchased from Analytical Biological Services and 11 BM samples were obtained at the screening from evaluable patients with relapsed/refractory AML enrolled in CA-4948-102 clinical trial.

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PMC11367146

Fig. 14Effect of VTE on changes in phosphorylation of (A) ERK2 (B) p38 (C) JNK and (D) STAT3 in IL-1β stimulated SW982 cell by ELISA test.

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PMC7338939

Recently, Norihiko Saito and colleagues have reported that GSI resistance results from a change in oncogene addiction, from NOTCH to constitutive AKT in glioblastoma, and that the combination of GSIs and PI3K inhibitors may reduce tumor growth in glioblastoma (51).

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PMC11388384

Cells were washed 3x in PBS and incubated at 4 °C overnight prior to imaging.

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PMC9429973

Image: Summary/Conclusion: Pts in the crizanlizumab MAP had significant disease burden at baseline, as evidenced by the high rate of home- and healthcare-managed VOCs, proportion of patients with SCD-related complications and use of opioids for VOC-related pain relief, despite many pts reporting prior HU use.

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PMC10968586

OLE and HT may also magnify the efficacy of other types of cancer treatment.

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PMC11394730

QUE has chemopreventive effects at low concentrations because it acts as an antioxidant; however, at high concentrations, it acts as a pro-oxidant and may have chemotherapeutic effects .

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PMC2196094

Clones showing positive hybridization signals with the PCR primer but were negative with the RMCP-2-specific probe were selected for further analysis.

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PMC11534377

Efficacy monitoring was achieved using recurrent IVIS Imaging, concluding in terminal macroscopic metastatic analysis post-euthanasia after 32 days.

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PMC11756514

The ability of the HEK293-Langerin, HEK293-MGL, or HEK293-empty vector cell lines to bind neoglycoproteins was examined using neoglycoproteins having ~20 monosaccharides coupled per BSA molecule (according to the manufacturer).

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PMC11400680

Further enhancement can be achieved by augmenting the prompt generator to increase its generalizability specifically for nucleus segmentation.

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PMC9509578

Stimuli-responsive nanosystems take advantage of unique cellular properties including pH variation, redox potential as well as enzymatic activation to overcome the MDR phenomena.

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PMC9429973

If not available, CCP or PFC can be used.

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PMC11474209

In addition, utilities should explore methods to limit the entry of cells into the plant or implement steps to address possible cyanotoxins.

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PMC9429973

Based on these findings, we developed expanded CMPs (exCMPs) that leverage the spleen environment to improve early hematopoietic recovery after transplantation.

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PMC11628904

For infection experiments, zebrafish larvae were exposed to C. albicans diluted in E3 medium without methylene blue to a final concentration of 1 × 10 cells/mL beginning immediately after burn wounding.

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PMC11129910

The possibility of tumor suppressor genes on the X chromosome was raised a few years ago, and studies suggested that the loci on the X chromosome carry tumor suppressor genes .

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PMC11389534

However, neither UFM1 nor DDRGK1 is required for insulin release mediated by glucose.

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PMC8524093

Indeed, infection of these cells is a key step for stablishing the disease since CHIKV titer is rapidly increased, which is essential to reach other targets without being completely neutralized by host immune system.

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PMC11777207

Alternatively, avelumab’s binding affinity to PD-L1 is approximately 10-fold stronger with a Kd = 0.0467 nM, a critical distinction in binding kinetics compared to avelumab and durvalumab (36).

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PMC10490530

Recently, many bioluminescence mushroom species have been reported which are evolutionarily divergent from other known terrestrial or marine species .

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PMC11774251

Immunoblotting of K1, K6 and K17 in HaCaT cells.

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PMC8735881

Effects of CMI constructs on the surface expression of CD4, CCR5, and CXCR4 in transduced TZM-bl cells were detected by FACS analysis using a PE-conjugated anti-human CD4, CCR5, or CXCR4 antibody and judged by fluorescence intensity.

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PMC11291490

DEFs were subjected to transfection with either pVAX-TPA (control) or pVAX-TPA-dusCD40L (dusCD40L) using TransIntroTM EL Transfection Reagent (TransGen Biotech, China) as per the manufacturer’s instructions.

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PMC11532793

We evaluated the computational performance of bootstrap and Gibbs sampling algorithms during transcript quantification with Salmon using our simulated RNA-seq experiments.

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PMC9429973

Results: As of data cutoff on 5 May 2021, 65 treated pts had at least 4 months of follow-up on or after study drug treatment.

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PMC10578720

The endpoint was set at 10 weeks from treatment initiation. (

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PMC10522430

A suspension of 400 L binding buffer incorporating 5 L annexin V-FITC and 10 L PI was prepared, and a 10-minute incubation at 4°C in darkness ensued.

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PMC9429973

To decipher the underlying molecular pathomechanism, we defined the molecular partners of RhoG in human lymphocytes and discovered that RhoG interacts with the regulator of cytotoxic granule (CG) release Munc13-4 inducing docking of Munc13-4-positive CGs to the plasma membrane.

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PMC3888431

Our reference-based pipeline predicted 5,636 new putative gene loci in addition to the 24,238 gene loci predicted by Xu et al. (Figure 8a), extending the total set of putative gene loci in the CHO-K1 genome to 28,596.

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PMC10197932

At 2T treatment, Jurkat cells do not show necrotic effect as AML cell lines (Figure 2A).

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PMC9592219

TOP2A promotes tumor progression through the Hippo pathway.

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PMC10114490

These cells can be maintained in fibroblast culture media, under standard cell culture conditions.

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PMC11730320

This was not primarily due to an increase in the dominant circulating γδ+ T cell population (typically Vγ9δ2), but rather, emergence of a large population determined to be 75% Vδ1+, with the remainder Vδ1-Vδ2- (Fig. 5A, B).

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PMC11539788

Finally, the samples were subjected to immunoblotting to detect ubiquitin.

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PMC6889484

Figure 4Absence of Selection for NL4-3 Variants that Can Replicate in CEM/D128K Cells(A) NL4-3 virus was used to infect different ratios of CEM:CEM/D128K cells.

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PMC11621565

Mono-colonization with curli-producing Escherichia coli worsened motor impairments and gastrointestinal issues in α-synuclein-overexpressing mice, enhancing α-synuclein aggregation and inflammation in the gut and brain.

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PMC9509578

A liposomal nanoformulation was the first clinically approved nanosystem for anticancer drug delivery .

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PMC10482220

G3BP oligomerization in vitro. (

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PMC9960565

For metallodendrimers’ hemotoxicity assessment, 10% (v/v) of a blood solution was prepared in PBS (Mg/Ca free).

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PMC11774251

Statistical significance is indicated as *P <0.05, **P <0.01, ***P <0.001, ****P <0.0001, ns = not significant.

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PMC11794568

Real-time quantitative polymerase chain reaction (RT-qPCR) and Western blots (WB) were used to detect stable overexpression and knockdown of CRIP1 in melanoma cells.

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PMC6450504

For flow cytometry analysis, spheroids were washed twice with PBS and dispersed into single cells by 10 min incubation with AccuMax cell detachment/disassociation solution at 37 °C (Sarisozen et al., 2016).

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PMC11754784

Source data are provided as a Source Data file.

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PMC11528603

In the cytoplasm, the formation of APAF1 complex with other proteins resulted in apoptosome that activates pro-caspase 9.

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PMC11534035

As the concentration of G1 was increased to 2.5 and 5 μM, the reduction in tumor sphere size became significant (2.5 μM: M=9,478±2,481 px vs. control; p<0.0001; 5 μM: M=10,931±1,815 px vs. control; p<0.001).

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PMC2196094

To minimize potential misunderstandings upon comparisons of mouse and rat MC proteases we have suggested a nomenclature which as close as possible harmonises between the corresponding proteases in these two species.

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PMC9429973

The kinetics and function of CAR-T cells was monitored by quantitative PCR and flow cytometry.

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PMC9429973

Methods: Retrospective data analysis of all pediatric patients diagnosed with (VWD) throughout a period of 10 years, dating from January 2012 till December 2021.

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PMC10376064

Twenty mg of homogenate was mixed with 10 µL cold Tris-buffered saline (TBS, pH 7.5, containing protease inhibitor (Roche, Germany)) per 1 mg brain.

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PMC11748335

We monitored the number of peaks in LOCKs and typical peaks, finding that a WScutoff of approximately −0.7 yielded a stable count of both types of peaks (Fig. S1A-B).

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PMC11590870

The effect of the first two doses was not statistically different from that of the negative control.

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PMC11704135

These derivatives possess the ability to scavenge reactive oxygen species (ROS) and inhibit oxidative damage to cellular components.

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PMC10198699

Specificatio would not be applicable (as the research institution is not acting in good faith) and the present-day Henrietta Lacks would automatically be the owner of the cell line derived from her tissue sample.

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