OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC9429973	The most frequent (≥ 5%) treatment-emergent related AEs (Grade ≥3) included thrombocytopenia (34%), neutropenia (22%), ALT/AST elevation (6%), dry eye (6%) and blurred vision (6%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10197932	After 2T US-treatment, lymphocytes have about 81.2% of cells (with respect to untreated control) with high GSH content, and only 17.9% of cells with low GSH content as shown in Figure 9J and Figure 9M.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10890307	Two 24-well plates were seeded equivalently.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Two", "24-well", "plates", "were", "seeded", "equivalently", "." ] } ]
PMC11755467	Consequently, the fact that MT-4 cells are insensitive to Enoxacin-mediated modulation of hsa-miR-132 processing may be attributed to a potential counter-effect of HTLV-1 or other cell-intrinsic factors, in which the RNAi machinery cannot be further tuned by Enoxacin, possibly explaining our negative result.	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11295144	GABAAR and NL2 interaction is mediated by the γ2 subunit intracellular loop. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GABAAR", "and", "NL2", "interaction", "is", "mediated", "by", "the", ...
PMC8873393	G Distribution of CDS and full sizes for the “induced”, “repressed” and “recovered” annotated lncRNA transcripts.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "G", ...
PMC9368503	PCR products were run on 1.5% agarose gels with SYBR safe DNA gel stain (Invitrogel) and visualised using UV illumination.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PCR", ...
PMC11615743	While these conditions are adequate for constructing DNA logic devices on living cell membranes for diagnostic purposes, cells labeled with DNA probes under these conditions typically take several hours and become less viable, rendering them unsuitable for further therapeutic applications.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10812665	An energetic stress may only be indirectly deduced, by the depletion of phospho-creatine (Creatine-P) (Figure 11).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "An", "energetic", ...
PMC11126803	NaOH (1 M) was used to neutralize the pH (pH 7, 10–20 μl 1 μM NaOH) (39).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10297204	In this regard, ensuring complete cure and preservation of limb function are sometimes a contrary and challenging issue in orthopedic oncology.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "this",...
PMC9105697	Following resection of the primary tumor, about one third to half of the patients suffer from recurrence.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Following", "resection", "of", "the", ...
PMC11687663	Instead Schaftoside (B7) showed the best stability to binds with receptor and showed the significant potency.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Instead", "Schaftoside", "(", "B7", ")...
PMC9429973	Evaluation of specific cytotoxic T cell response after vaccination was performed in HLA-A0201 positive CLL and MM patients with the most common and the highest binding score SARS-CoV-2 specific epitope - HLA-A0201/YLQPRTFLL269-277.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11481779	We compute the residual heatmap by taking the difference between the real heatmap and the one produced by the encoder-decoder architecture.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "compute", "...
PMC10656496	The identities of the lines were confirmed using STR analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "identities", "of", "the", "lines", "were", "confirmed", "using", "STR", "analysis", ...
PMC11155445	The t-butyl group on the aromatic ring and thiourea functionality in the synthesized compounds were the reasons behind the antiviral activity of these compounds.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11680049	Experiments have experimentally established that the conditions of cultivation, such as the type of vessel (Petri dishes or tubes) and lighting conditions (in light or darkness), significantly influence the intensity of callus tissue formation, its consistency, and its color (Figure 4 and Figure 5).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8592717	Mitochondria are also morphologically and functionally altered, leading to excessive ROS formation and decrease in energy due to the reduction in ATP production, alteration of calcium homeostasis, and apoptosis induction .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: To characterize the genetic and non-genetic intra-patient heterogeneity at single cell resolution in CK-AML.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "To", "characterize", "the", "genetic", ...
PMC11777207	Last, we enumerated the frequency and number of IL-17–producing CD4 T cells within the dLN and observed a reduction in frequency and number of IL-17–producing CD4 T cells after ex vivo stimulation of cells from the dLN of αPD-L1 43H12–treated mice (Fig. 7, H to J) and Pdl1 mice (Fig. 7, K to M).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5839394	The concentration necessary for 50% of growth inhibition (IC50) was calculated using a dose–response model, which was obtained from sigmoidal fitting of response curves of percent inhibition versus logarithmic concentration of DOSs using Graph Pad Prism software.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The annual incidence is 1.5 cases per million per year, with two peaks in frequency: in postpartum women (2 to 15%) and in patients aged over 60 (75%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11803918	Our results showed that, compared with liposomes, hybrid exosomes had an active targeting effect toward melanoma cells and led to higher drug accumulation levels within tumor tissues, which might be attributed to their surface functional markers, including PD-1 and CCR5, interacting with melanoma cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11674146	As a crucial player in cytoskeletal organization and organ development, CLP36/PDLIM1 has been recently demonstrated to be dysregulated in a variety of cancers with important roles in the proliferation and metastasis during tumor initiation and progression (Zhou et al., 2021).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11711127	As discussed, much evidence supports the heavy interlinking functionality of tolDCs and Treg activity, as both induce differentiation of the other in some models and contexts, and Tregs are potent mediators of immune suppression and tolerance in their own right (114115).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3931643	Antibody dilutions were performed according to the manufacturer's instructions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Antibody", "dilutions", "were", "performed", "according", "to", "the", "manufacturer", "'s", "in...
PMC11612794	The human CENP-T residues V219, F222, and L226, corresponding to I202, F205, and V209 of chicken CENP-T, are predicted to bind to the hydrophobic region of human Mis12C Head1 domain (Figure S3I).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10440586	The UMAP plot of hypoxia score in HF3016 GSCs from the Johnson et al. dataset. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "UMAP", "plot", "of", "hypoxia", "score...
PMC11412721	Under these conditions, Raji cells of all genotypes appeared to proliferate similarly (Figure 4—figure supplement 4).	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Under", "these", "conditions",...
PMC11726183	As a result, the isatin nucleus has been widely employed in the synthesis of a variety of potent oxindole-based small molecules with anticancer properties that target various cellular and enzymatic targets, including the initiation of apoptosis in different human cancer cell lines and the inhibition of the carbonic anh...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11612508	Colloidal stability is crucial for secure drug delivery in biological environments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Colloidal", "stability", "is", "crucial", "for", "secure", "drug", "delivery", "in", ...
PMC11740508	We hypothesized that inhibition of PARP plus inhibition of DNMT1 would most likely benefit patients with HRR deficient tumors, since these tumors repeatedly undergo erroneous DNA repair during treatment exposure.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11401350	In parallel, T cells were pre-stimulated with IL-7 and IL-15 and transduced with mCD8-LVs at equivalent physical particles content (p24).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC11185260	MRI-based measurement of tumor volume on day 49. *	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MRI-based", "measurement", "of", "tumor", "volume", "on", "day", "49", ".", "*" ] } ]
PMC9878278	However, our data clearly shows that ZIKV does not modulate either TGF-β1 or Activin A expression, and exogenous treatment of TGF-β and Activin A also does not affect ZIKV replication kinetics.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7039683	Each DNA library was quantified using a KAPA Library Quantification Kit (Roche, Mannheim, Germany) and pooled for HiSeq4000 (Illumina) high-throughput sequencing at the same molarity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10174970	In the pancreatic cancer pathway, all 33 cell lines were not poorly correlated with the tumor (r>0.3), and they could be chosen for studying the pathway of pancreatic cancer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10213199	This study aimed to explore the RNA changes and potential biological processes related to the anti-aging or life-extending effects of JYL treatments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "stud...
PMC11683240	This further supports the hypothesis that the protease activity of α1AT is not relevant for the inhibition of PT, since in our experiments another protease inhibitor of the serpin family, antithrombin, did not inhibit PT.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11742864	DHA is also considered as a natural ligand of PPARγ, and the EPA derivatives such as PGD3 and 15-deoxy-d12,14-PGJ3 induce the anti-inflammatory adipokine lipocalin production via activating PPARγ.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11766350	This would also explain the strong differences observed in the percentage of GFP positive cells, when comparing the anti-gfp shRNA + TRAIL sample to the non-TRAIL control (Figure 3a).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Results: From the 3006 abstracts identified (May 20, 2021), 17 publications (12 studies: 6 randomized controlled trials, 2 single-arm trials, and 4 retrospective studies) satisfied the inclusion criteria (Table).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9220170	Thus, SELENOK is involved in the regulation of the ERAD system and is involved in maintaining ER homeostasis .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", "SELENOK", "is", ...
PMC11411131	Ornithine decarboxylase (odc), a target for proteasome degradation, was expected to suppress luciferase activity under full-length protein expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ornithine", ...
PMC4005030	The ethanolic polyphenolic extracts of H. sabdariffa possess significant antioxidant and hyperlipidemic activities.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "ethanolic", "polyphenolic", "extracts", "of", "H.", "sabdariffa", "p...
PMC11794568	In this study, we systematically revealed the oncogenic role of CRIP1 in cutaneous melanoma for the first time.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "this", "study", ",", ...
PMC11585254	A phospho-site cluster located medially along the CT plays a minor role in β-arrestin1 or β-arrestin2 recruitment, whereas a membrane-proximal phospho-site cluster has no role.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11698348	However, further analyses are required to determine its mechanistic role in these cell SC populations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "further", "analyses", "are", "required...
PMC11562028	Then, the systems were fixed with 4% paraformaldehyde for 30 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", "the", "systems", "were", "fixed", "with", "4", "%", ...
PMC5261804	SMAD7 has been implicated in colon cancer development , and in interactions with β-catenin in pancreatic cancer and prostate cancer .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SMAD7", "has", "been", ...
PMC9429973	Aims: To evaluate in this study the clinical, biological and therapeutic aspects of AIHA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "To", "evaluate", "in", "this", "stu...
PMC11538390	CP cases were defined using the same ICD code-based inclusion and exclusion criteria as in FinnGen (see Phenotype definitions).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CP", "cases", "we...
PMC11269933	The HTSeq v0.6.0 tool was used to count the reads for each gene in each sample to quantify gene expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "HTSeq", "v0.6.0", ...
PMC11424574	Tumor metastasis, the spread of cells from the primary tumor to other sites to form secondary tumors, is a major factor contributing to cancer-related mortality .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8973085	Found: C, 61.31; H, 4.77; N, 8.22.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Found", ":", "C", ",", "61.31", ";", "H", ",", "4.77", ";", ...
PMC11530949	Indicates P<0.05, indicates P<0.01 and * indicates P<0.001.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Indicates", "P<0.05", ",", "", "", "indicates", "P<0.01", "and", "*...
PMC10178190	Oil red is extracted with isopropanol, and an absorbance of 492 nm was measured by spectrophotometer (Tecan, Männedorf, Switzerland).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11650848	The standard deviations were low and tightly clustered between groups, C/C (SD = 6.88), C/T (SD = 4.08) and T/T (SD = 8.60) (Additional File 2: Table S5).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11422150	The procedure has been described previously (Kuramoto et al., 2022a).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "procedure", "has", "been", "described", "previously", "(", "Kuramoto...
PMC10329074	The mRNA level of YBX3 was detected by qPCR. *	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mRNA", "level", "of", "YBX3", "was", "detected", "by", "qPCR", ".", "*" ] } ]
PMC11502327	Kaempferol is a natural polyphenol compound, widely found in the daily consumption of vegetables, fruits and some Chinese herbs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Kaempferol", "is", ...
PMC11519567	The qPCR primer sequences are listed in Supplementary Table S1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "qPCR", "primer", "sequences", "are", "listed", "in", "Supplementary", "Table", "S1", ...
PMC11806818	Liu et al. constructed an electrochemical cytosensor with triple signal amplification based on Fe3O4@Au nanozyme and DNAzyme hybrids, an electrochemical cytosensor with triple signal amplification was constructed for sensitive detection of HepG2 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4277423	Infectious molecular clones of HIV-1 strain Bru3 and Bru-Yu2 and infectious molecular clones of transmitted/founder (T/F) HIV-1 isolates, pWITO, pCH040, pTHRO, pREJO, and pCH106 were obtained from ARRRP, Germantown, MD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11507371	Media served as controls, while for positive controls, 0.5 μg/mL hydrogen peroxide was added.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Media", "served", "as", "controls", ",", "while", ...
PMC9429973	Aims: The aims of this study are to develop a novel adult mouse model of a-thal and a gene therapy approach for this disease.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10993311	BMI: Body Mass Index.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "BMI", ":", "Body", "Mass", "Index", "." ] } ]
PMC11634027	The RMCE cassette within ds was subsequently substituted by site-specific recombination either with wild-type ds sequences or with ds sequences in which one of the conserved motifs was deleted, or the entire Ds-ICD was deleted.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	For pts with R/R peripheral (PTCL) and transformed cutaneous TCL (CTCL), median OS is 1-2.5 and <5 yrs, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9080589	Caspase-3 is a frequently activated death protease, catalyzing the specific cleavage of various key cellular proteins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Caspase-3", "is", "a", "frequently", "activated",...
PMC10993311	Enrichment analysis of DMGMs showed that the COL3A1 module was related to 21 biological processes and 8 diseases, focused on regulation of blood pressure and cardiovascular and hypertensive diseases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11701801	Data are presented as the mean ± SEM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "presented", "as", "the", "mean", "±", "SEM", "." ] } ]
PMC9429973	Aims: We analyze the incidence and type of second malignancy in a single institute in 20 years.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "We", "analyze", "the", ...
PMC10443665	MDR1 mRNA expression in CCRF-CEM/MTX cells in 48 h exposure to APS, tragacanthin, and bassorin. *	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MDR1", "mRNA", "expression", "in", ...
PMC11711127	In 2022, A study by Lindsay et al. (170) revealed that NK cells play a significant role in enhancing the expression of homing receptor ligands on tumour vasculature and controlled the development of anergic T cells, leading to improved tumour control.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Although men comprised the majority of detected cases (62%), mortality at four and eight weeks was near identical between sexes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC4355729	However, only a small number of patients benefit from single-agent PI3K targeted therapy11.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "only", "a", "small", "number", "of", ...
PMC11496728	The development of more cell lines and processes is necessary to obtain stable clones with desirable production characteristics, which will increase protein yields.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11413393	Given the role of BCLAF1 and THRAP3 in the pre-mRNA splicing and nuclear export of genes involved in DDR pathways, we selected a subset of disrupted DDR genes from our previously generated RNA-seq and Western blot assays and carried out qRT-PCR assays on isolated cytoplasmic and nuclear RNA using primers spanning exon-...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10944868	This discernment carries profound ramifications for the pharmacokinetic profile of pharmaceutical agents.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "discernment", "carries", "profound", "ramifications", "for", "the", "pharmacok...
PMC7090062	At 48 h after transfection, relative Renilla luciferase activity (firefly luciferase/Renilla luciferase) was measured in dual luciferase reporter assays.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "48", ...
PMC9429973	TP53, del(17p) and IGHV status was unknown for 20, 18 and 42 patients, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TP53", ",", "del(17p", ")", "and", ...
PMC10482220	In contrast, G3BP-GFP lacking domain A could not interact with wild-type G3BP, suggesting that it indeed mediates protein multimerization (see Fig. 5 A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7452526	Then readings were taken at ×150K magnification with steady voltage (20 kV).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", "readings", "were", "taken", "at", "×150", "K", ...
PMC11023271	Albumin is a major carrier of lipids/fatty acids in serum .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Albumin", "is", "a", "major", "carrier", "of", "lipids/fatty", "acids", "in", "serum", "."...
PMC9341513	A t(11;14) translocation often found in mantle cell lymphoma (and in the Z-138 cell line) which brings CCND1 next to the entire IGH constant region is shown.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	of Copenhagen; The Finsen Laboratory; Dept.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "of", "Copenhagen", ";", "The", "Finsen", "Laboratory", ";", "Dept", "." ] } ]
PMC9429973	We focused our analysis on AZA and SC in pts with IR-MDS ineligible for alloSCT.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "focused", "our", "analysis", "on", "AZA", "and", ...
PMC11767817	These results suggest that the increase in oxidative stress leads to the activation of antioxidant defense rather than oxidative stress-induced cell death.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "res...
PMC11190538	C-phycocyanin was examined in vitro for anti-proliferative efficacy against human cancer cell lines, HepG-2 (liver cancer), MCF-7 (breast cancer), and HCT-116 (colon cancer) using the MTT assay versus one human healthy cell line (BJ-1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "...
PMC9503541	Studies show that extracts and metabolites from guyabano, particularly the leaves, reduce tumor growth and inhibit the formation of various types of cancer cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973	Written informed consent was obtained from all pts.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Written", "informed", "consent", "was", "obtained", "from", "all", "pts", "." ] } ]
PMC11471176	Angiotensin-converting enzyme 2 (ACE2) is a pivotal molecular nexus linking novel coronavirus disease to breast cancer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Angiotensin-converting", "enzyme", "2", "(",...
PMC11569208	Transfection was performed using Lipofectamine™ RNAiMAX Transfection Reagent (Thermo Fisher, cat.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Transfection", "was", "performed", "using", "Lipofectamine", "™", "RNA...
PMC9105697	One possibility is to enhance the conversion rate of the assay.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "possibility", "is", "to", "enhance", "the", "conversion", "rate", "of", "the",...
PMC9429973	Methods: RNA-seq data from 2 adult cohorts and one pediatric AML cohort was retrieved.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Methods", ":", "RNA-seq", "data", "from", "2", "adult", ...
PMC10747139	The complexes that showed the highest cytotoxic activities, 52 and 53, were then chosen to analyze their effects on the distribution of HeLa cells in the cell-cycle phases using flow cytometry analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11449273	These observations suggest that plakoglobin’s effects on PUMA and BAX expression is mutant p53-specific since WT-p53 does not interfere with plakoglobin’s effect on PUMA and BAX levels.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11224020	Flow cytometry was performed on an LSRII flow cytometer (BD Biosciences), and data were analyzed using FlowJo software version 10.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Flow", ...

PMC9429973

The most frequent (≥ 5%) treatment-emergent related AEs (Grade ≥3) included thrombocytopenia (34%), neutropenia (22%), ALT/AST elevation (6%), dry eye (6%) and blurred vision (6%).

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PMC10197932

After 2T US-treatment, lymphocytes have about 81.2% of cells (with respect to untreated control) with high GSH content, and only 17.9% of cells with low GSH content as shown in Figure 9J and Figure 9M.

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PMC10890307

Two 24-well plates were seeded equivalently.

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PMC11755467

Consequently, the fact that MT-4 cells are insensitive to Enoxacin-mediated modulation of hsa-miR-132 processing may be attributed to a potential counter-effect of HTLV-1 or other cell-intrinsic factors, in which the RNAi machinery cannot be further tuned by Enoxacin, possibly explaining our negative result.

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PMC11295144

GABAAR and NL2 interaction is mediated by the γ2 subunit intracellular loop. (

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PMC8873393

G Distribution of CDS and full sizes for the “induced”, “repressed” and “recovered” annotated lncRNA transcripts.

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PMC9368503

PCR products were run on 1.5% agarose gels with SYBR safe DNA gel stain (Invitrogel) and visualised using UV illumination.

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PMC11615743

While these conditions are adequate for constructing DNA logic devices on living cell membranes for diagnostic purposes, cells labeled with DNA probes under these conditions typically take several hours and become less viable, rendering them unsuitable for further therapeutic applications.

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PMC10812665

An energetic stress may only be indirectly deduced, by the depletion of phospho-creatine (Creatine-P) (Figure 11).

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PMC11126803

NaOH (1 M) was used to neutralize the pH (pH 7, 10–20 μl 1 μM NaOH) (39).

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PMC10297204

In this regard, ensuring complete cure and preservation of limb function are sometimes a contrary and challenging issue in orthopedic oncology.

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PMC9105697

Following resection of the primary tumor, about one third to half of the patients suffer from recurrence.

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PMC11687663

Instead Schaftoside (B7) showed the best stability to binds with receptor and showed the significant potency.

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PMC9429973

Evaluation of specific cytotoxic T cell response after vaccination was performed in HLA-A*0201 positive CLL and MM patients with the most common and the highest binding score SARS-CoV-2 specific epitope - HLA-A*0201/YLQPRTFLL269-277.

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PMC11481779

We compute the residual heatmap by taking the difference between the real heatmap and the one produced by the encoder-decoder architecture.

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PMC10656496

The identities of the lines were confirmed using STR analysis.

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PMC11155445

The t-butyl group on the aromatic ring and thiourea functionality in the synthesized compounds were the reasons behind the antiviral activity of these compounds.

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PMC11680049

Experiments have experimentally established that the conditions of cultivation, such as the type of vessel (Petri dishes or tubes) and lighting conditions (in light or darkness), significantly influence the intensity of callus tissue formation, its consistency, and its color (Figure 4 and Figure 5).

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PMC8592717

Mitochondria are also morphologically and functionally altered, leading to excessive ROS formation and decrease in energy due to the reduction in ATP production, alteration of calcium homeostasis, and apoptosis induction .

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PMC9429973

Aims: To characterize the genetic and non-genetic intra-patient heterogeneity at single cell resolution in CK-AML.

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PMC11777207

Last, we enumerated the frequency and number of IL-17–producing CD4 T cells within the dLN and observed a reduction in frequency and number of IL-17–producing CD4 T cells after ex vivo stimulation of cells from the dLN of αPD-L1 43H12–treated mice (Fig. 7, H to J) and Pdl1 mice (Fig. 7, K to M).

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PMC5839394

The concentration necessary for 50% of growth inhibition (IC50) was calculated using a dose–response model, which was obtained from sigmoidal fitting of response curves of percent inhibition versus logarithmic concentration of DOSs using Graph Pad Prism software.

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PMC9429973

The annual incidence is 1.5 cases per million per year, with two peaks in frequency: in postpartum women (2 to 15%) and in patients aged over 60 (75%).

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PMC11803918

Our results showed that, compared with liposomes, hybrid exosomes had an active targeting effect toward melanoma cells and led to higher drug accumulation levels within tumor tissues, which might be attributed to their surface functional markers, including PD-1 and CCR5, interacting with melanoma cells.

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PMC11674146

As a crucial player in cytoskeletal organization and organ development, CLP36/PDLIM1 has been recently demonstrated to be dysregulated in a variety of cancers with important roles in the proliferation and metastasis during tumor initiation and progression (Zhou et al., 2021).

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PMC11711127

As discussed, much evidence supports the heavy interlinking functionality of tolDCs and Treg activity, as both induce differentiation of the other in some models and contexts, and Tregs are potent mediators of immune suppression and tolerance in their own right (114115).

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PMC3931643

Antibody dilutions were performed according to the manufacturer's instructions.

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PMC11612794

The human CENP-T residues V219, F222, and L226, corresponding to I202, F205, and V209 of chicken CENP-T, are predicted to bind to the hydrophobic region of human Mis12C Head1 domain (Figure S3I).

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PMC10440586

The UMAP plot of hypoxia score in HF3016 GSCs from the Johnson et al. dataset. (

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PMC11412721

Under these conditions, Raji cells of all genotypes appeared to proliferate similarly (Figure 4—figure supplement 4).

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PMC11726183

As a result, the isatin nucleus has been widely employed in the synthesis of a variety of potent oxindole-based small molecules with anticancer properties that target various cellular and enzymatic targets, including the initiation of apoptosis in different human cancer cell lines and the inhibition of the carbonic anh...

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PMC11612508

Colloidal stability is crucial for secure drug delivery in biological environments.

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PMC11740508

We hypothesized that inhibition of PARP plus inhibition of DNMT1 would most likely benefit patients with HRR deficient tumors, since these tumors repeatedly undergo erroneous DNA repair during treatment exposure.

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PMC11401350

In parallel, T cells were pre-stimulated with IL-7 and IL-15 and transduced with mCD8-LVs at equivalent physical particles content (p24).

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PMC11185260

MRI-based measurement of tumor volume on day 49. *

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PMC9878278

However, our data clearly shows that ZIKV does not modulate either TGF-β1 or Activin A expression, and exogenous treatment of TGF-β and Activin A also does not affect ZIKV replication kinetics.

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PMC7039683

Each DNA library was quantified using a KAPA Library Quantification Kit (Roche, Mannheim, Germany) and pooled for HiSeq4000 (Illumina) high-throughput sequencing at the same molarity.

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PMC10174970

In the pancreatic cancer pathway, all 33 cell lines were not poorly correlated with the tumor (r>0.3), and they could be chosen for studying the pathway of pancreatic cancer.

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PMC10213199

This study aimed to explore the RNA changes and potential biological processes related to the anti-aging or life-extending effects of JYL treatments.

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PMC11683240

This further supports the hypothesis that the protease activity of α1AT is not relevant for the inhibition of PT, since in our experiments another protease inhibitor of the serpin family, antithrombin, did not inhibit PT.

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PMC11742864

DHA is also considered as a natural ligand of PPARγ, and the EPA derivatives such as PGD3 and 15-deoxy-d12,14-PGJ3 induce the anti-inflammatory adipokine lipocalin production via activating PPARγ.

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PMC11766350

This would also explain the strong differences observed in the percentage of GFP positive cells, when comparing the anti-gfp shRNA + TRAIL sample to the non-TRAIL control (Figure 3a).

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PMC9429973

Results: From the 3006 abstracts identified (May 20, 2021), 17 publications (12 studies: 6 randomized controlled trials, 2 single-arm trials, and 4 retrospective studies) satisfied the inclusion criteria (Table).

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PMC9220170

Thus, SELENOK is involved in the regulation of the ERAD system and is involved in maintaining ER homeostasis .

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PMC11411131

Ornithine decarboxylase (odc), a target for proteasome degradation, was expected to suppress luciferase activity under full-length protein expression.

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PMC4005030

The ethanolic polyphenolic extracts of H. sabdariffa possess significant antioxidant and hyperlipidemic activities.

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PMC11794568

In this study, we systematically revealed the oncogenic role of CRIP1 in cutaneous melanoma for the first time.

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PMC11585254

A phospho-site cluster located medially along the CT plays a minor role in β-arrestin1 or β-arrestin2 recruitment, whereas a membrane-proximal phospho-site cluster has no role.

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PMC11698348

However, further analyses are required to determine its mechanistic role in these cell SC populations.

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PMC11562028

Then, the systems were fixed with 4% paraformaldehyde for 30 min.

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PMC5261804

SMAD7 has been implicated in colon cancer development , and in interactions with β-catenin in pancreatic cancer and prostate cancer .

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PMC9429973

Aims: To evaluate in this study the clinical, biological and therapeutic aspects of AIHA.

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PMC11538390

CP cases were defined using the same ICD code-based inclusion and exclusion criteria as in FinnGen (see Phenotype definitions).

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PMC11269933

The HTSeq v0.6.0 tool was used to count the reads for each gene in each sample to quantify gene expression.

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PMC11424574

Tumor metastasis, the spread of cells from the primary tumor to other sites to form secondary tumors, is a major factor contributing to cancer-related mortality .

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PMC8973085

Found: C, 61.31; H, 4.77; N, 8.22.

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PMC11530949

Indicates P<0.05, ** indicates P<0.01 and *** indicates P<0.001.

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PMC10178190

Oil red is extracted with isopropanol, and an absorbance of 492 nm was measured by spectrophotometer (Tecan, Männedorf, Switzerland).

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PMC11650848

The standard deviations were low and tightly clustered between groups, C/C (SD = 6.88), C/T (SD = 4.08) and T/T (SD = 8.60) (Additional File 2: Table S5).

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PMC11422150

The procedure has been described previously (Kuramoto et al., 2022a).

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PMC10329074

The mRNA level of YBX3 was detected by qPCR. *

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PMC11502327

Kaempferol is a natural polyphenol compound, widely found in the daily consumption of vegetables, fruits and some Chinese herbs.

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PMC11519567

The qPCR primer sequences are listed in Supplementary Table S1.

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PMC11806818

Liu et al. constructed an electrochemical cytosensor with triple signal amplification based on Fe3O4@Au nanozyme and DNAzyme hybrids, an electrochemical cytosensor with triple signal amplification was constructed for sensitive detection of HepG2 cells.

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PMC4277423

Infectious molecular clones of HIV-1 strain Bru3 and Bru-Yu2 and infectious molecular clones of transmitted/founder (T/F) HIV-1 isolates, pWITO, pCH040, pTHRO, pREJO, and pCH106 were obtained from ARRRP, Germantown, MD.

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PMC11507371

Media served as controls, while for positive controls, 0.5 μg/mL hydrogen peroxide was added.

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PMC9429973

Aims: The aims of this study are to develop a novel adult mouse model of a-thal and a gene therapy approach for this disease.

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PMC10993311

BMI: Body Mass Index.

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PMC11634027

The RMCE cassette within ds was subsequently substituted by site-specific recombination either with wild-type ds sequences or with ds sequences in which one of the conserved motifs was deleted, or the entire Ds-ICD was deleted.

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PMC9429973

For pts with R/R peripheral (PTCL) and transformed cutaneous TCL (CTCL), median OS is 1-2.5 and <5 yrs, respectively.

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PMC9080589

Caspase-3 is a frequently activated death protease, catalyzing the specific cleavage of various key cellular proteins.

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PMC10993311

Enrichment analysis of DMGMs showed that the COL3A1 module was related to 21 biological processes and 8 diseases, focused on regulation of blood pressure and cardiovascular and hypertensive diseases.

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PMC11701801

Data are presented as the mean ± SEM.

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PMC9429973

Aims: We analyze the incidence and type of second malignancy in a single institute in 20 years.

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PMC10443665

MDR1 mRNA expression in CCRF-CEM/MTX cells in 48 h exposure to APS, tragacanthin, and bassorin. *

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PMC11711127

In 2022, A study by Lindsay et al. (170) revealed that NK cells play a significant role in enhancing the expression of homing receptor ligands on tumour vasculature and controlled the development of anergic T cells, leading to improved tumour control.

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PMC9429973

Although men comprised the majority of detected cases (62%), mortality at four and eight weeks was near identical between sexes.

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PMC4355729

However, only a small number of patients benefit from single-agent PI3K targeted therapy11.

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PMC11496728

The development of more cell lines and processes is necessary to obtain stable clones with desirable production characteristics, which will increase protein yields.

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PMC11413393

Given the role of BCLAF1 and THRAP3 in the pre-mRNA splicing and nuclear export of genes involved in DDR pathways, we selected a subset of disrupted DDR genes from our previously generated RNA-seq and Western blot assays and carried out qRT-PCR assays on isolated cytoplasmic and nuclear RNA using primers spanning exon-...

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PMC10944868

This discernment carries profound ramifications for the pharmacokinetic profile of pharmaceutical agents.

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PMC7090062

At 48 h after transfection, relative Renilla luciferase activity (firefly luciferase/Renilla luciferase) was measured in dual luciferase reporter assays.

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PMC9429973

TP53, del(17p) and IGHV status was unknown for 20, 18 and 42 patients, respectively.

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PMC10482220

In contrast, G3BP-GFP lacking domain A could not interact with wild-type G3BP, suggesting that it indeed mediates protein multimerization (see Fig. 5 A).

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PMC7452526

Then readings were taken at ×150K magnification with steady voltage (20 kV).

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PMC11023271

Albumin is a major carrier of lipids/fatty acids in serum .

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PMC9341513

A t(11;14) translocation often found in mantle cell lymphoma (and in the Z-138 cell line) which brings CCND1 next to the entire IGH constant region is shown.

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PMC9429973

of Copenhagen; The Finsen Laboratory; Dept.

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PMC9429973

We focused our analysis on AZA and SC in pts with IR-MDS ineligible for alloSCT.

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PMC11767817

These results suggest that the increase in oxidative stress leads to the activation of antioxidant defense rather than oxidative stress-induced cell death.

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PMC11190538

C-phycocyanin was examined in vitro for anti-proliferative efficacy against human cancer cell lines, HepG-2 (liver cancer), MCF-7 (breast cancer), and HCT-116 (colon cancer) using the MTT assay versus one human healthy cell line (BJ-1).

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PMC9503541

Studies show that extracts and metabolites from guyabano, particularly the leaves, reduce tumor growth and inhibit the formation of various types of cancer cells .

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PMC9429973

Written informed consent was obtained from all pts.

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PMC11471176

Angiotensin-converting enzyme 2 (ACE2) is a pivotal molecular nexus linking novel coronavirus disease to breast cancer.

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PMC11569208

Transfection was performed using Lipofectamine™ RNAiMAX Transfection Reagent (Thermo Fisher, cat.

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PMC9105697

One possibility is to enhance the conversion rate of the assay.

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PMC9429973

Methods: RNA-seq data from 2 adult cohorts and one pediatric AML cohort was retrieved.

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PMC10747139

The complexes that showed the highest cytotoxic activities, 52 and 53, were then chosen to analyze their effects on the distribution of HeLa cells in the cell-cycle phases using flow cytometry analysis.

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PMC11449273

These observations suggest that plakoglobin’s effects on PUMA and BAX expression is mutant p53-specific since WT-p53 does not interfere with plakoglobin’s effect on PUMA and BAX levels.

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PMC11224020

Flow cytometry was performed on an LSRII flow cytometer (BD Biosciences), and data were analyzed using FlowJo software version 10.

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