OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11680049	The following cell cultures obtained from the collection of the Institute of Cytology of the Russian Academy of Sciences (St. Petersburg, Russia) were used in the study: FetMSC (human embryonic mesenchymal stem cells), A-172 (human glioblastoma), HeLa (human cervical adenocarcinoma, clone M), and HepG2 (human hepatocel...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11792766	However, within the acidic environment of the lysosomes, the dye becomes positively charged and is retained.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "within", "the", "acidi...
PMC11748335	C Comparing short LOCKs to the whole genome based on Roadmap samples.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "C", "Comparing", "short", "LOCKs", "to", "the", "whole", "genome", "based", ...
PMC11632064	Equal amounts of total proteins (10 μg) were denatured in sample buffer (50 mM Tris–HCl pH 6.8, 100 mM DTT, 2% SDS, <1.5 mM bromophenol blue 1.5 mM, 1.075 M glycerol) at 95°C for 5 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11449273	The pCMV-Neo-Bam-p53 (p53 in which arginine 273 is replaced with histidine) plasmid was purchased from Addgene (USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "pCMV-Neo-Bam-p53...
PMC11575040	Quantitative polymerase chain reaction (PCR) measurements revealed a significant reduction in the relative expression of si-LINC00094 in A2058 and A375 cells with si-LINC00094 transfection compared with the control group (Fig. 2B, C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "...
PMC9429973	Pts were randomized 1:1:1 to either receive obin 1 mo before ibr, ibr 1 mo before obin, or start concomitantly.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Pts", "were"...
PMC11615743	Therefore, successful DNA‐based logic gate computation on living cell membranes thus depends on cell‐friendly conditions, usually involving fetal bovine serum (FBS), where DNA‐labeled cells can be propagated further.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7369657	The tumor volume inhibition rate was 38.9%.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "tumor", "volume", "inhibition", "rate", "was", "38.9", "%", "." ] } ]
PMC7192625	DDX23 is an early RT gene involved in splicing which interacts with other early RT genes involved in other basic cellular processes (chromatin remodelling, protein modifications etc.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11754784	k Simulated kinetic curve of different species in DNP1-based computation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "k", "Simulated", "kinetic", "curve", "of", "different", "species", "in", "DNP1-based", "computat...
PMC11731614	N = 3 male biological replicates for both RD and HFD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "N", "=", "3", "male", "biological", "replicates", "for", "both", "RD", "and", "...
PMC9429973	Flexible parametric survival models were used to estimate marginal childbirth rates and standardized cumulative incidence of childbirth across treatment groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Flexible", "parametric", "su...
PMC9583612	In this paper, we have anonymized the basin names and present results from the baseline phase and key observations from the enhanced monitoring phase of the project.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Addition of FLT3-i to FL and SL regimen in subset of pts with FLT3-ITD mutation is beneficial and should be further evaluated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Addition", "...
PMC11538390	All participants had a Finnish genetic ancestry determined by a principal component (PC) analysis of their genotypes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "participants", "had", "a",...
PMC9429973	However, more than half of the patients will not proceed to ASCT due to progressive disease.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "more", "than", "half", "of"...
PMC10850553	All the raw data from RNA sequencing analysis was deposited to Gene Expression Omnibus (https://www.ncbi.nlm.nih.gov/geo/) (ID # Data will be deposited after the acceptance).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11756514	However, the majority of S. aureus strains produce CP, which is highly dependent on the bacterial culture conditions (40).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However...
PMC11461874	Data are presented as mean ± SEM (n = 4).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "presented", "as", "mean", "±", "SEM", "(", "n", "=", ...
PMC10976516	This figure is adapted from Hadryś et al. Studies showed that administering MSCs intravenously causes significant initial trapping in the lungs, most likely due to the large size of MSCs and their accumulation in the capillary beds of the lung.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6379402	We measure the overall dissimilarity between two networks by using graphlet corelation distance (GCD), because it is the most sensitive network distance measure.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11443022	45,X/46,XY mosaicism represents a rare chromosomal mutation and is classified as a type of mixed gonadal dysgenesis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "45,X/46,XY", "mosaicism", "represents", "a", "rar...
PMC11306019	The vicinal diol group of polyphenols can react with the boronic group of BTZ and neutralize BTZ´s anticancer effect (Golden et al., 2009; Kim et al., 2009; Jia and Liu, 2013; Tseeleesuren et al., 2018b).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Recently novel SRC family kinase (SFK) inhibitors based on the pyrazolol[3,4-d]-pyramidine scaffold were shown to inhibit Pgp in two MDR cancer cell lines with the proforms outlining a stronger potential to modulate Pgp .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11562028	The mice in the 5-FU group were administered with the drug at a dosage of 15 mg kg every 3 days (intraperitoneal injection).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11711127	We will discuss different types of resistance mechanisms based on their molecular and cellular origins and their (patho-)physiological implications.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "will", "discuss", "differen...
PMC10253973	Ruthenium compounds are used for discovering new drugs to address problems connected with anti-HIV therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ruthenium", "compounds", "are", "used", "for", "discovering", ...
PMC2944824	In the ER stress pathway, for example, the unfolded protein response results in increased expression of protein chaperones such as GRP78 and transcription factors CHOP and ATF4 , .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Median time from enrollment to infusion was 35 d (range, 7-62 d).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Median", "time", "from", "enrollment", "to", ...
PMC9429973	Results: Among the 2491 newly-diagnosed MZL patients (median age = 63 years; 52% male), 59% were commercially insured (median age = 57 years) and 41% in Medicare (median age = 76 years).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11655498	BDLF4, a viral protein expressed early in viral lysis, is a component of the lytic gene regulatory complex.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "BDLF4", ",", "a", "vir...
PMC10538569	RLU in HIV-1 pseudotyped AD8, Bru-3, Yu2, CNE3, CNE11, Con B, Con C or JRFL-captured mDCs alone were included for the comparison.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11377827	n = 5 biologically independent samples, mean ± sd. ****	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "n", "=", "5", "biologically", "independent", "samples", ",", "me...
PMC11013014	M.p.	[ { "tags": [ "O", "O" ], "tokens": [ "M.p", "." ] } ]
PMC11806106	Further, in our approach the C terminus was truncated, removing most of the phosphorylation sites in the C terminus which are required for arrestin interaction.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10969097	If no dose-limiting toxicities were detected during the first 28 days of treatment, the next higher dose (up to 14 g/day) was tested.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC8998437	Chemokines transmit signals via chemokine receptors, which are G protein-coupled, cell-surface receptors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Chemokines", "transmit", "signals", "via", "chemokine", "receptors", "...
PMC10899471	Cell viability was determined by using Cell Counting Kit 8 (CCK-8) (Dojindo, Kumamoto, Japan) after 48 h or a Bromodeoxyuridine (BrdU) ELISA kit (Roche, Burgess Hill, UK) according to the manufacturer’s instructions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6450504	Equally important, bPEI has the desirable characteristics of hydrophilic polymers that are used to stabilize formulations, including flexible chains and a hydrophilic nature, which are known to provide reduced opsonization.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10831439	For that, CD19-CAR-iNKT cells were challenged for 4 hours with K562 cells modified to stably express CD19 and/or CD1d (figure 2A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "token...
PMC11476106	Cell cultures were maintained at 37 °C with 5% CO2 in T75 cell culture flasks (plus 0.1% gelatin coated in the case of PDX73 to facilitate cell adhesion).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	30 (77%) patients were the candidates for autoHSCT.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "30", "(", "77", "%", ")", "patients", "were", "the", "candidates", "for", "auto...
PMC4485786	Intravenous injection of the constructs caused no visible systemic toxicity acutely or over an extended time (Fig. 1B: 4 mice/cohort, 100 d).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11684269	Therefore, to keep the maintenance within the kidney, the CD8 TRM cell necessitates cognate antigen and IL-15 in the context of transplantation or inflammation (139, 140).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11756907	The hydrophobic moieties of 2-ME can interact favourably with the hydrophobic domains of rGO, resulting in stable binding or adsorption.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "hydrophobic", ...
PMC9516401	The MTT assay determined cell proliferation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "MTT", "assay", "determined", "cell", "proliferation", "." ] } ]
PMC3734024	In the absence of cognate peptide, B cells stimulated with CD40L alone or in conjunction with IL-5 induced slightly higher levels of apoptosis than were induced by fresh CD19 B cells (Figures 6A and 6B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11352746	A35829-01) supplemented with B27plus (Gibco Cat. #	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A35829", "-", "01", ")", "supplemented", "with", "B27plus", "(", "Gibco", "Cat", ...
PMC11656380	Since caspase activation did not occur during Tat-Ram13-induced cell death, we investigated whether changes in mitochondrial membrane potential were responsible.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Since", "caspase", ...
PMC11803149	Lymphocytes isolated from tumors were stained with anti-CD8a antibody and ZombieNIR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lymphocytes", "isolated", "from", "tumors", "were", "stained", "with", "anti-CD8a", "antibo...
PMC9398137	The pro-survival MCL1 protein is overexpressed in many cancers, including B-cell non–Hodgkin lymphomas (B-NHL).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "pro-survival", "MCL1", "pr...
PMC9243326	2020; Qiu.,	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "2020", ";", "Qiu", ".", "," ] } ]
PMC11750712	For the standard cytotoxicity assay, mock (non-transduced PBMCs) and CAR-transduced T cells were co-cultured with TRBC1 or TRBC2 non-transduced T cells, TRBC1, TRBC2 or TCR knockout Jurkat target cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Among fully vaccinated patients the achievement of viral clearance by day 14 was more frequent than in unvaccinated patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Among", "fully", "vaccinated", "p...
PMC9429973	CLL treatment history had no impact on CFR, as well as anemia (Hb<100g/l) that was present in 29/81(35.8%)pts, hipogammaglobulinemia (21/81;26%pts) and hiperferritinemia>450ng/mL (50/81;61.7%pts).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11381192	D, E) Kaplan–Meier curves of OS and EFS for patients grouped by CSI risk in the GSE24080 training set. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11012313	As shown in Figure 3A,B, LMP2A-expressing BJAB (LMP2A1.1) and LMP2A-expressing Ramos (pmp2) cells do not have higher levels of HIF-1α RNA (Figure 3A,B), suggesting that the mechanism for increasing HIF-1α levels in LMP2A-expressing cells is post-transcriptional.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11739484	Wound healing assay images at 0 and 24. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Wound", "healing", "assay", "images", "at", "0", "and", "24", ".", "(" ] } ]
PMC9964635	Off-white, amorphous solid.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Off-white", ",", "amorphous", "solid", "." ] } ]
PMC11126803	D, quantification of the metastases in the four groups of mice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "D", ",", "quantification", "of", "the", "metastases", "in", "the", "four", ...
PMC11257203	The average percentage of micronuclei was significantly decreased in the group treated concomitantly with indomethacin (100 and 200 μΜ) and curcumin compared to the groups treated only with the same concentration of indomethacin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7841067	Compared with the sh-NC group, the number of cells that migrated was significantly reduced in ACT-1 cells transfected with sh-AKAP4 (Fig. 3A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC8753818	For instance, p21 and p27, cyclin E and Rb (Cdk inhibitors) regulate the progression of cell cycle from G1 to S phases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC8916024	We observed that Aeromonas was the primary biomarker of the snail gut and sediments (P < 0.001), and it may be a cellulose-degrading bacteria.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10891340	In the release stage of DPV, the cell supernatant was collected from 18 hpi for TCID50 detection, we observed there was no inhibitory effect in the CCCP treated group as compared to the control group (Figure 4D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11411131	Depletion of Sec and resulting in a premature termination codon (PTC) at TGA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Depletion", "of", "Sec", "and", "resulting", "in", "a", ...
PMC9429973	Aims: We describe data collected from the COVID-19 & ITP survey within the ITP Natural History Patient Registry on PC drops following both viral infection and vaccination to compare the effects of each on individuals with ITP.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9118379	The results showed that only FDR criterion is insufficient to validate identified variant peptides and the 11 postexaminations can reveal low-confidence variant events detected by shotgun proteomics experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11703992	The redder, the more significant; The bluer, the less significant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "redder", ",", "the", "more", "significant", ";", "The", "bluer...
PMC8922418	For example, we identified three highly conserved important sites (S532P, T534A and T536A) that can affect the binding of gp120 to the CD4 receptor during HIV-1 entry into cells (Lu et al., 2019).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11593713	Although it has been clearly understood that reactive oxygen and nitrogen species production causes lung tissue injury and epithelial barrier dysfunction in the course of viral, bacterial, and parasitic infections, the molecular inflammation mechanisms of oxidative stress contributing to infection progression still nee...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9577200	Furthermore, Oves et al. (2020a) discovered that graphitic C3N4@ Polyaniline Composites are an effective antimicrobial agent and have high stability at temperatures above 100°C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9065483	786-0 cells were treated ± vanadate (150 μM) ± gefitinib (10 μM), then infected with VSVΔ51-GFP (MOI 0.1) 4 h later.	[ { "tags": [ "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC10578720	In summary, these results suggest that HBV-mediated aberrant activation of the TLR2-NF-κB-PGC-1α axis in macrophages significantly contributed to the downregulation of SIRT3 expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11740573	The process is likely to be mediated by the vitamin D receptor (VDR), which is expressed not only on immune cells but on nearly all cells in the body [30–32].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	An adequate number of stem cells must be collected for better ASCT outcomes, which is challenging in 5-30% of patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC7602170	Activated S6K can inhibit the function of mTORC2 via a negative feedback loop (Figure 2) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Activated", "S6", "K", "can", "inhibit...
PMC8010066	For example, some virulence factors of P. aeruginosa, including LasA protease, play a more beneficial role in enhancing beta-lactamase resistance (Alves et al. 2018).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11190538	Functional bioactive ingredients isolated from microalgae as sustainable sources have become a new subject of pharmacology and functional foods.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Functional", "bioactive", "ingredients"...
PMC11806818	The dual-mode biosensor proposed in this study is expected to open up a promising future for exosome detection in biological research and clinical applications.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11011837	Notably, recent studies demonstrated the feasibility of stratifying patients with acute myeloid leukemia (AML) using a lipidomic approach, revealing different lipid profiles among patients with distinct cytogenetic alterations .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2196094	The coding region is followed by a 3′ untranslated region of 246 bp with the non-canonical ATTAAA polyadenylation signal located at position 1061.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC11726848	The degree of cell staining was assessed using the Image J software v. 1.54g (LOCI, University of Wisconsin, Madison, WI, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8633974	TatDE rLNP showed a narrower size distribution with a PDI of 0.045 and an average diameter of 76.11 nm. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TatDE", "rLNP", "showed", ...
PMC11656380	These data suggest that the Tat-Ram13 can inhibit NOTCH signaling by competitively inhibiting the interaction between CSL and NICD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "data", "suggest", "that"...
PMC9429973	The dose-expansion part will commence subsequent to RP2D determination.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "dose-expansion", "part", "will", "commence", "subsequent", "to", "RP2D", "determination", "." ] ...
PMC11590005	Mann-Whitney test Kruskal-Wallis and post-hoc test HEI = Higher Education Institution; N = Number of participants; SD = Standard Deviation; Min = Mínimum; Max = Máximum; P = Probability value.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11761919	Schematic diagram of in vivo experiment in chicken.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Schematic", "diagram", "of", "in", "vivo", "experiment", "in", "chicken", "." ] } ]
PMC11588008	Protein imprinting and real-time fluorescence quantitative PCR were used to detect extracellular regulated protein kinase (ERK), p-ERK heme oxygenase-1 (HO-1), and nuclear factor E2-related factor 2 (Nrf2) protein levels.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11676674	Gentiana lutea extract also showed the hormesis phenomenon, where at lower non-genotoxic doses provided significant protection against 2-amino-3-methyl-3H-imidazo[4,5-f]quinolone and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced genotoxicity in genetically modified Salmonella typhimurium TA1535 when as...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10926885	The most vulnerable NDE1 mutation locations are shown in Figure 3A.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "most", "vulnerable", "NDE1", "mutation", "locations", "are", "shown", "in", "F...
PMC8409415	We examined 63 ovarian cancer clinical samples; 43 (68.3%) of them expressed CD70.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "examined", "63", "ovarian", "cancer", ...
PMC9221284	In summary, we report for the first time the concept of multi-transcript genesis as a tool for the development of Burkitt’s lymphoma in the case of t(8;22) translocation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8303372	As it can be seen, the release curve has a very steep slope in the first 4 h, then it decreases significantly up to 72 h, at the end of the experiment, when a cumulative GA release of 18–20% is reached.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9000591	Therefore, this sample was selected for further fractionation of the bioactive components involved in antioxidant and cytotoxic activities.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "this", "sample"...
PMC6222635	However, no studies have reported pharmacological differences between these two planting modes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "no", "studies", "have", "reported", "pharmacological", "dif...
PMC11519583	Wnt signaling is critical in the regulation of organogenesis, tissue regeneration, and tumor development and progression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Wnt", "signaling", "is", "critical", "...
PMC9516401	A sample of 20 µl of the plant extract (10 mg/ml) or gallic acid as the standard (50-500 mg/L) was mixed with 100 µl of the Folin-Ciocalteu reagent and 300 µl of sodium carbonate solution (1 mol/L).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	A large body of evidence has suggested that transforming growth factor beta (TGF-β) is among the most prominent inducers of fibrotic processes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11680049

The following cell cultures obtained from the collection of the Institute of Cytology of the Russian Academy of Sciences (St. Petersburg, Russia) were used in the study: FetMSC (human embryonic mesenchymal stem cells), A-172 (human glioblastoma), HeLa (human cervical adenocarcinoma, clone M), and HepG2 (human hepatocel...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11792766

However, within the acidic environment of the lysosomes, the dye becomes positively charged and is retained.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "within", "the", "acidi...

PMC11748335

C Comparing short LOCKs to the whole genome based on Roadmap samples.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "C", "Comparing", "short", "LOCKs", "to", "the", "whole", "genome", "based", ...

PMC11632064

Equal amounts of total proteins (10 μg) were denatured in sample buffer (50 mM Tris–HCl pH 6.8, 100 mM DTT, 2% SDS, <1.5 mM bromophenol blue 1.5 mM, 1.075 M glycerol) at 95°C for 5 min.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11449273

The pCMV-Neo-Bam-p53 (p53 in which arginine 273 is replaced with histidine) plasmid was purchased from Addgene (USA).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "pCMV-Neo-Bam-p53...

PMC11575040

Quantitative polymerase chain reaction (PCR) measurements revealed a significant reduction in the relative expression of si-LINC00094 in A2058 and A375 cells with si-LINC00094 transfection compared with the control group (Fig. 2B, C).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "...

PMC9429973

Pts were randomized 1:1:1 to either receive obin 1 mo before ibr, ibr 1 mo before obin, or start concomitantly.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Pts", "were"...

PMC11615743

Therefore, successful DNA‐based logic gate computation on living cell membranes thus depends on cell‐friendly conditions, usually involving fetal bovine serum (FBS), where DNA‐labeled cells can be propagated further.

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PMC7369657

The tumor volume inhibition rate was 38.9%.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "tumor", "volume", "inhibition", "rate", "was", "38.9", "%", "." ] } ]

PMC7192625

DDX23 is an early RT gene involved in splicing which interacts with other early RT genes involved in other basic cellular processes (chromatin remodelling, protein modifications etc.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11754784

k Simulated kinetic curve of different species in DNP1-based computation.

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PMC11731614

N = 3 male biological replicates for both RD and HFD.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "N", "=", "3", "male", "biological", "replicates", "for", "both", "RD", "and", "...

PMC9429973

Flexible parametric survival models were used to estimate marginal childbirth rates and standardized cumulative incidence of childbirth across treatment groups.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Flexible", "parametric", "su...

PMC9583612

In this paper, we have anonymized the basin names and present results from the baseline phase and key observations from the enhanced monitoring phase of the project.

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PMC9429973

Addition of FLT3-i to FL and SL regimen in subset of pts with FLT3-ITD mutation is beneficial and should be further evaluated.

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PMC11538390

All participants had a Finnish genetic ancestry determined by a principal component (PC) analysis of their genotypes.

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PMC9429973

However, more than half of the patients will not proceed to ASCT due to progressive disease.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "more", "than", "half", "of"...

PMC10850553

All the raw data from RNA sequencing analysis was deposited to Gene Expression Omnibus (https://www.ncbi.nlm.nih.gov/geo/) (ID # Data will be deposited after the acceptance).

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PMC11756514

However, the majority of S. aureus strains produce CP, which is highly dependent on the bacterial culture conditions (40).

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PMC11461874

Data are presented as mean ± SEM (n = 4).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "presented", "as", "mean", "±", "SEM", "(", "n", "=", ...

PMC10976516

This figure is adapted from Hadryś et al. Studies showed that administering MSCs intravenously causes significant initial trapping in the lungs, most likely due to the large size of MSCs and their accumulation in the capillary beds of the lung.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC6379402

We measure the overall dissimilarity between two networks by using graphlet corelation distance (GCD), because it is the most sensitive network distance measure.

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PMC11443022

45,X/46,XY mosaicism represents a rare chromosomal mutation and is classified as a type of mixed gonadal dysgenesis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "45,X/46,XY", "mosaicism", "represents", "a", "rar...

PMC11306019

The vicinal diol group of polyphenols can react with the boronic group of BTZ and neutralize BTZ´s anticancer effect (Golden et al., 2009; Kim et al., 2009; Jia and Liu, 2013; Tseeleesuren et al., 2018b).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Recently novel SRC family kinase (SFK) inhibitors based on the pyrazolol[3,4-d]-pyramidine scaffold were shown to inhibit Pgp in two MDR cancer cell lines with the proforms outlining a stronger potential to modulate Pgp .

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PMC11562028

The mice in the 5-FU group were administered with the drug at a dosage of 15 mg kg every 3 days (intraperitoneal injection).

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PMC11711127

We will discuss different types of resistance mechanisms based on their molecular and cellular origins and their (patho-)physiological implications.

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PMC10253973

Ruthenium compounds are used for discovering new drugs to address problems connected with anti-HIV therapy.

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PMC2944824

In the ER stress pathway, for example, the unfolded protein response results in increased expression of protein chaperones such as GRP78 and transcription factors CHOP and ATF4 , .

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PMC9429973

Median time from enrollment to infusion was 35 d (range, 7-62 d).

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PMC9429973

Results: Among the 2491 newly-diagnosed MZL patients (median age = 63 years; 52% male), 59% were commercially insured (median age = 57 years) and 41% in Medicare (median age = 76 years).

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PMC11655498

BDLF4, a viral protein expressed early in viral lysis, is a component of the lytic gene regulatory complex.

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PMC10538569

RLU in HIV-1 pseudotyped AD8, Bru-3, Yu2, CNE3, CNE11, Con B, Con C or JRFL-captured mDCs alone were included for the comparison.

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PMC11377827

n = 5 biologically independent samples, mean ± sd. ****

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PMC11013014

M.p.

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PMC11806106

Further, in our approach the C terminus was truncated, removing most of the phosphorylation sites in the C terminus which are required for arrestin interaction.

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PMC10969097

If no dose-limiting toxicities were detected during the first 28 days of treatment, the next higher dose (up to 14 g/day) was tested.

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PMC8998437

Chemokines transmit signals via chemokine receptors, which are G protein-coupled, cell-surface receptors.

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PMC10899471

Cell viability was determined by using Cell Counting Kit 8 (CCK-8) (Dojindo, Kumamoto, Japan) after 48 h or a Bromodeoxyuridine (BrdU) ELISA kit (Roche, Burgess Hill, UK) according to the manufacturer’s instructions.

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PMC6450504

Equally important, bPEI has the desirable characteristics of hydrophilic polymers that are used to stabilize formulations, including flexible chains and a hydrophilic nature, which are known to provide reduced opsonization.

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PMC10831439

For that, CD19-CAR-iNKT cells were challenged for 4 hours with K562 cells modified to stably express CD19 and/or CD1d (figure 2A).

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PMC11476106

Cell cultures were maintained at 37 °C with 5% CO2 in T75 cell culture flasks (plus 0.1% gelatin coated in the case of PDX73 to facilitate cell adhesion).

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PMC9429973

30 (77%) patients were the candidates for autoHSCT.

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PMC4485786

Intravenous injection of the constructs caused no visible systemic toxicity acutely or over an extended time (Fig. 1B: 4 mice/cohort, 100 d).

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PMC11684269

Therefore, to keep the maintenance within the kidney, the CD8 TRM cell necessitates cognate antigen and IL-15 in the context of transplantation or inflammation (139, 140).

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PMC11756907

The hydrophobic moieties of 2-ME can interact favourably with the hydrophobic domains of rGO, resulting in stable binding or adsorption.

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PMC9516401

The MTT assay determined cell proliferation.

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PMC3734024

In the absence of cognate peptide, B cells stimulated with CD40L alone or in conjunction with IL-5 induced slightly higher levels of apoptosis than were induced by fresh CD19 B cells (Figures 6A and 6B).

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PMC11352746

A35829-01) supplemented with B27plus (Gibco Cat. #

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PMC11656380

Since caspase activation did not occur during Tat-Ram13-induced cell death, we investigated whether changes in mitochondrial membrane potential were responsible.

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PMC11803149

Lymphocytes isolated from tumors were stained with anti-CD8a antibody and ZombieNIR.

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PMC9398137

The pro-survival MCL1 protein is overexpressed in many cancers, including B-cell non–Hodgkin lymphomas (B-NHL).

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PMC9243326

2020; Qiu.,

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PMC11750712

For the standard cytotoxicity assay, mock (non-transduced PBMCs) and CAR-transduced T cells were co-cultured with TRBC1 or TRBC2 non-transduced T cells, TRBC1, TRBC2 or TCR knockout Jurkat target cells.

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PMC9429973

Among fully vaccinated patients the achievement of viral clearance by day 14 was more frequent than in unvaccinated patients.

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PMC9429973

CLL treatment history had no impact on CFR, as well as anemia (Hb<100g/l) that was present in 29/81(35.8%)pts, hipogammaglobulinemia (21/81;26%pts) and hiperferritinemia>450ng/mL (50/81;61.7%pts).

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PMC11381192

D, E) Kaplan–Meier curves of OS and EFS for patients grouped by CSI risk in the GSE24080 training set. (

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PMC11012313

As shown in Figure 3A,B, LMP2A-expressing BJAB (LMP2A1.1) and LMP2A-expressing Ramos (pmp2) cells do not have higher levels of HIF-1α RNA (Figure 3A,B), suggesting that the mechanism for increasing HIF-1α levels in LMP2A-expressing cells is post-transcriptional.

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PMC11739484

Wound healing assay images at 0 and 24. (

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PMC9964635

Off-white, amorphous solid.

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PMC11126803

D, quantification of the metastases in the four groups of mice.

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PMC11257203

The average percentage of micronuclei was significantly decreased in the group treated concomitantly with indomethacin (100 and 200 μΜ) and curcumin compared to the groups treated only with the same concentration of indomethacin.

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PMC7841067

Compared with the sh-NC group, the number of cells that migrated was significantly reduced in ACT-1 cells transfected with sh-AKAP4 (Fig. 3A).

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PMC8753818

For instance, p21 and p27, cyclin E and Rb (Cdk inhibitors) regulate the progression of cell cycle from G1 to S phases.

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PMC8916024

We observed that Aeromonas was the primary biomarker of the snail gut and sediments (P < 0.001), and it may be a cellulose-degrading bacteria.

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PMC10891340

In the release stage of DPV, the cell supernatant was collected from 18 hpi for TCID50 detection, we observed there was no inhibitory effect in the CCCP treated group as compared to the control group (Figure 4D).

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PMC11411131

Depletion of Sec and resulting in a premature termination codon (PTC) at TGA.

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PMC9429973

Aims: We describe data collected from the COVID-19 & ITP survey within the ITP Natural History Patient Registry on PC drops following both viral infection and vaccination to compare the effects of each on individuals with ITP.

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PMC9118379

The results showed that only FDR criterion is insufficient to validate identified variant peptides and the 11 postexaminations can reveal low-confidence variant events detected by shotgun proteomics experiments.

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PMC11703992

The redder, the more significant; The bluer, the less significant.

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PMC8922418

For example, we identified three highly conserved important sites (S532P, T534A and T536A) that can affect the binding of gp120 to the CD4 receptor during HIV-1 entry into cells (Lu et al., 2019).

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PMC11593713

Although it has been clearly understood that reactive oxygen and nitrogen species production causes lung tissue injury and epithelial barrier dysfunction in the course of viral, bacterial, and parasitic infections, the molecular inflammation mechanisms of oxidative stress contributing to infection progression still nee...

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PMC9577200

Furthermore, Oves et al. (2020a) discovered that graphitic C3N4@ Polyaniline Composites are an effective antimicrobial agent and have high stability at temperatures above 100°C.

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PMC9065483

786-0 cells were treated ± vanadate (150 μM) ± gefitinib (10 μM), then infected with VSVΔ51-GFP (MOI 0.1) 4 h later.

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PMC10578720

In summary, these results suggest that HBV-mediated aberrant activation of the TLR2-NF-κB-PGC-1α axis in macrophages significantly contributed to the downregulation of SIRT3 expression.

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PMC11740573

The process is likely to be mediated by the vitamin D receptor (VDR), which is expressed not only on immune cells but on nearly all cells in the body [30–32].

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PMC9429973

An adequate number of stem cells must be collected for better ASCT outcomes, which is challenging in 5-30% of patients.

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PMC7602170

Activated S6K can inhibit the function of mTORC2 via a negative feedback loop (Figure 2) .

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PMC8010066

For example, some virulence factors of P. aeruginosa, including LasA protease, play a more beneficial role in enhancing beta-lactamase resistance (Alves et al. 2018).

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PMC11190538

Functional bioactive ingredients isolated from microalgae as sustainable sources have become a new subject of pharmacology and functional foods.

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PMC11806818

The dual-mode biosensor proposed in this study is expected to open up a promising future for exosome detection in biological research and clinical applications.

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PMC11011837

Notably, recent studies demonstrated the feasibility of stratifying patients with acute myeloid leukemia (AML) using a lipidomic approach, revealing different lipid profiles among patients with distinct cytogenetic alterations .

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PMC2196094

The coding region is followed by a 3′ untranslated region of 246 bp with the non-canonical ATTAAA polyadenylation signal located at position 1061.

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PMC11726848

The degree of cell staining was assessed using the Image J software v. 1.54g (LOCI, University of Wisconsin, Madison, WI, USA).

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PMC8633974

TatDE rLNP showed a narrower size distribution with a PDI of 0.045 and an average diameter of 76.11 nm. (

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PMC11656380

These data suggest that the Tat-Ram13 can inhibit NOTCH signaling by competitively inhibiting the interaction between CSL and NICD.

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PMC9429973

The dose-expansion part will commence subsequent to RP2D determination.

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PMC11590005

Mann-Whitney test Kruskal-Wallis and post-hoc test HEI = Higher Education Institution; N = Number of participants; SD = Standard Deviation; Min = Mínimum; Max = Máximum; P = Probability value.

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PMC11761919

Schematic diagram of in vivo experiment in chicken.

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PMC11588008

Protein imprinting and real-time fluorescence quantitative PCR were used to detect extracellular regulated protein kinase (ERK), p-ERK heme oxygenase-1 (HO-1), and nuclear factor E2-related factor 2 (Nrf2) protein levels.

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PMC11676674

Gentiana lutea extract also showed the hormesis phenomenon, where at lower non-genotoxic doses provided significant protection against 2-amino-3-methyl-3H-imidazo[4,5-f]quinolone and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced genotoxicity in genetically modified Salmonella typhimurium TA1535 when as...

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PMC10926885

The most vulnerable NDE1 mutation locations are shown in Figure 3A.

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PMC8409415

We examined 63 ovarian cancer clinical samples; 43 (68.3%) of them expressed CD70.

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PMC9221284

In summary, we report for the first time the concept of multi-transcript genesis as a tool for the development of Burkitt’s lymphoma in the case of t(8;22) translocation.

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PMC8303372

As it can be seen, the release curve has a very steep slope in the first 4 h, then it decreases significantly up to 72 h, at the end of the experiment, when a cumulative GA release of 18–20% is reached.

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PMC9000591

Therefore, this sample was selected for further fractionation of the bioactive components involved in antioxidant and cytotoxic activities.

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PMC6222635

However, no studies have reported pharmacological differences between these two planting modes.

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PMC11519583

Wnt signaling is critical in the regulation of organogenesis, tissue regeneration, and tumor development and progression.

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PMC9516401

A sample of 20 µl of the plant extract (10 mg/ml) or gallic acid as the standard (50-500 mg/L) was mixed with 100 µl of the Folin-Ciocalteu reagent and 300 µl of sodium carbonate solution (1 mol/L).

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PMC9429973

A large body of evidence has suggested that transforming growth factor beta (TGF-β) is among the most prominent inducers of fibrotic processes.

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