OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11155445	These ligands show different coordination modes and have diverse applications in biological systems.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "ligands", "show", "different", "coordination", "modes", "and", "ha...
PMC11300639	g–i 786-O cells were transfected with the indicated plasmids or siRNAs for 48 h, or treated with Palbociclib (5 μM) for 24 h. Cells were treated with CHX, and cells were collected for western blotting analysis at different time points.	[ { "tags": [ "B-CellLine", "I-CellLine", "I-CellLine", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11599565	Transdifferentiation” is hence limited to “differentiated” cells, and “metaplasia” comprises both transdifferentiation and switching in to stem cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11727062	Furthermore, β-elemene has been observed to exert no significant impact on the body weight or behavioral patterns of the mice, suggesting an absence of notable systemic toxic side effects (Shi et al. 2015).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11281366	On the other hand, among the 188 genes for which mRNA levels were upregulated, we also identified cellular genes relevant to HIV-1 infection.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11765988	Neoplastic antigens can trigger a T-helper-mediated hypersensitivity reaction, activating monocytes and forming epithelioid histiocytes .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Neoplastic", "antigens", "can", "trigger", "a", "T-helper-mediate...
PMC5941560	Deletion326108434(0%)(0%)Long Deletion1904118,61060812499125,397(61%)(1.4%)(10%)(1.2%)Long Insertion1039125,91818126,657(31%)(0.25%)(0%)Duplication17,762186315,288(22%)(24%)Inversion149,545183149,715(0.0087%)(7.1%)Intra.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "Deletion326108434(0%)(0%)Long", "Deletion1904118,61060812499125,397(61%)(1.4%)(10%)(1.2%)Long", "Insertion1039125,91818126,657(31%)(0.25%)(0%)Duplication17,762186315,288(22%)(24%)Inversion149,545183149,715(0.0087%)(...
PMC11697065	C and D: Correlation of mRNA abundance with protein abundance for LC (C) and HC (D) for all clones.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11754784	Source data are provided as a Source Data file.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Source", "data", "are", "provided", "as", "a", "Source", "Data", "file", "." ] } ]
PMC11697703	M.J.G. is the Stepping Stone Foundation Early Career Professor in Cell and Molecular Biology at Tulane University.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "M.J.G.", "is", "the", "Stepping", "Stone", ...
PMC9429973	No relapses occurred later than 39 mo after discontinuation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "relapses", "occurred", "later", "than", "39", "mo", "after", "discontinuation", "." ] } ]
PMC11621493	All other upregulated species were glycerophospholipids and sphingolipids (supplemental Fig. S8B and C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "other", "upregulated", "species", "were", "glycerophosphol...
PMC9429973	The addition of venetoclax to established intensive chemotherapy protocols in these trials are generally reported to be associated with enhanced efficacy, frequently at the cost of significant hematological and infectious toxicities that requires dose modifications of both chemotherapy and venetoclax dosing Aims: To as...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9727330	For staining ASNS enzyme, the rabbit monoclonal primary antibody (mAb #92479, Cell Signaling Technology, USA) and goat anti-rabbit IgG (Alexa Fluor 488, Abcam, USA) were used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11271278	We grouped the loops, called by hichipper, into “normal,” “abnormal cis”, and “trans” groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC7553912	Quantitative analysis of the protein expressions of OPN, ANXA1, ANXA2, and TGF-β in the RTECs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Quantitative", "analysis", "of", "the", ...
PMC11401358	Lingpeng Zhan: Data curation, Formal analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lingpeng", "Zhan", ":", "Data", "curation", ",", "Formal", "analysis", "." ] } ]
PMC11686380	Fig. 2The GAP43 p.E111K variant is unstable in vitro and in vivo (A, B) Expression of wild type and GAP43-E111K in COS7 cells (A) or dissociated mouse cortical neurons (B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11357960	However, local analysis of tumor tissue might be severely limited by the amount of available samples, especially since tissue would be consumed by routine molecular analyses (59).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10882807	P < 0.05, p < 0.01, *p < 0.001 Hsa_circ_0005397 affects proliferation in HCC cell lines. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC8041314	We found only 93 reports containing 1049 compounds that qualified for data processing.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "found", "only", "93", "reports", "containing", "1049", "compounds", ...
PMC7338939	Several reports have determined the role for aberrant Notch signaling in melanoma progression and have suggested that its inhibition may provide a valid therapeutic approach (16, 18).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Three patients (12.5%) were 65 years or older.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Three", "patients", "(", "12.5", "%", ")", "were", "65", "years", "or", "older"...
PMC9429973	Aims: This has been a trigger to start a registry for suspected ALPS patients for future genomic characterization.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "This", "has", ...
PMC2944824	JC1 monomers form in apoptotic and unhealthy cells and can measured at an excitation of 485 nm and emission 535 nm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "JC1", "monomers", ...
PMC11782508	Additionally, conventional PCR confirmed the expression of the azurin gene in the synthesized cDNA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "conventional", "PCR", "confirmed", "the", ...
PMC11473843	Mutant KRAS: mutKRAS; n = 3. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mutant", "KRAS", ":", "mutKRAS", ";", "n", "=", "3", ".", "(" ] } ]
PMC11453018	For senescence delay experiments, the staining period was shortened to 4 h for non-treated groups showing significant β-Gal positivity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "senescence", "delay",...
PMC8170755	Real-time polymerase chain reaction (RT-PCR) was used to determine gene expressions using SYBR Green Master Mix (Parstoos, Iran) and ABI Step One Real-Time PCR System (Applied Biosystems, Foster City, CA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6461034	In another study, the rhabdomyosarcoma‐derived cell line A204 was associated with PDGFRα signaling (Bai et al, 2012), and INKA scoring of the underlying data accordingly ranks PDGFRα in second place (Fig 4B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11188874	Positive control indicates E.G7-Ova cells treated with bortezomib at 10 nmol/L for 16 hours.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Positive", "control", "indicates", "E.G7-Ova", "cells", "treated", ...
PMC11672881	Gorreja et al. confirmed that ZP4 is regulated by Toll-like receptors and contributes to the immune response, particularly in inflammatory contexts .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Gorreja", "e...
PMC11204465	Compounds 31 and 32 had a significant effect on NO production in their anti-inflammatory activity and a slight inhibitory effect on THF-α and IL-6 expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11521786	Using DU145 and LN-Cap tumor cells as models, it was evident that sera containing anti-HER3 PAbs could also promote the degradation of HER1 and HER2.	[ { "tags": [ "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC9479186	Figure 1A ) Western blot results showed that, compared with Lv-shCtrl group, the protein levels of NDUFC1 in Lv-shNDUFC1 group were also significantly decreased ( Figure 1B ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11502327	At the same time, genetic mechanisms such as increased repair of DNA damage, disturbance of intracellular transduction pathways, and changes in cellular genes all act on the OC microenvironment and make the tumor resistant to drugs (23).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11190538	Table 6Anti-proliferative IC50 of C-PC against HepG-2, MCF-7, and HCT-116 cancer cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ "Table", "6Anti-proliferative", "IC50", "of", ...
PMC10530622	Increased dietary ingestion of oxalate and alterations in intestinal microbiota may further contribute to obesity-associated hyperoxaluria .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Increased", "dietary", "ingestion", "of", "oxalate", "...
PMC5363531	These data indicate that dasatinib sensitizes mesothelioma cells to PEM through TS down-regulation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "data", "indicate", "that", "dasatinib", "sensitizes", "mesothelioma", ...
PMC9429973	A network was constructed that composed RCTs (ALPINE, ELEVATE-RR [NCT02477696], ASCEND [NCT02970318], and MURANO [NCT02005471]).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973	Single versus multiple KIT or RAS mutations also do not seem to have an impact on therapy response.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Single", "versus", "multiple", "KIT", ...
PMC11473843	The normalization was performed with the ΔΔCT method.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "normalization", "was", "performed", "with", "the", "ΔΔCT", "method", "." ] } ]
PMC2196094	Hybridizations were carried out overnight in a solution containing 6× SSC, 3× Denhardts solution, 0.5% SDS, 2 mM EDTA, and 100 μg yeast RNA/ml at 65°C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5673060	5420 phosphosites on 1950 proteins were quantified in two or more replicates in the PazR/A204 experiments (Fig. 2A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "5420", "phosphosites", "on",...
PMC9429973	To further harness their use in patient-derived AML cells, we are exploring and optimizing targeted LNPs for effective siRNA delivery to primary leukaemic cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9219615	In conclusion, Tpz-1 is a potent and cytotoxic thieno[2,3-c]pyrazole derivative with potent and specific anticancer activity in vitro.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "conclusion", ",", "Tpz-1", ...
PMC5716223	All values are given as the mean ± standard deviation of the mean (SD).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "values", "are", "given", "as", "the", "me...
PMC11544122	The pEC50 was 9.474 for WT and 9.933 GRK KO (in an inverse manner), and the pEC50 was 9.630 for +GRK2/5, 9.665 for +GRK2 (in an inverse manner) and not detected (n.d.)	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11279397	The evaluation of drug similarity is crucial in the production and upgrading of drug entities .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "evaluation", "of", "drug", "similarity", "is", "cruc...
PMC9429973	M. Amatangelo, Y. Cheng, W. Pierceall, N. W. van de Donk, S. Lonial, M. Wang, J. Emerson, K. Hong, P. Maciag, T. Peluso, A. Gandhi, A. Thakurta Bristol Myers Squibb, Princeton, NJ, United States of America; Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Department of Hematology, Cancer Center Amster...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11694066	Cisplatin was used as the positive control.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cisplatin", "was", "used", "as", "the", "positive", "control", "." ] } ]
PMC10523483	Moreover, knockout of H1.2sensitized NSCLC cells to cisplatin, and low H1.2 was associated with longer survival of lung cancer patients who underwent chemotherapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	The mean age for severe COVID-19 was lower in patients with severe SCD (SS/SB0 vs SC/SB+: 23y vs 67.5y) and THAL (major vs intermedia: 43.5 vs 51.3y) (p<0.001).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11732523	Timely antiviral, antifungal, and antibiotic therapies, combined with immunoglobulin replacement and the antifibrotic agent nintedanib, were pivotal in managing infections and immune dysregulation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	CD33 AM exposure, which led to an outgrowth of pAML cells after 12 d, increasing AM concentrations and/or switching the target antigen improved AdCAR-T cell efficacy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11721587	All quantification data were analyzed by two-tailed Student’s t test.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "quantification", "data", "were", "analyzed", "by", "two-tailed", "Student", "’s", ...
PMC10154097	Henceforth, based on the median circSOX4 expression (Figure 1(a)), 50 HCC patients were assigned into a low- (n = 25) and a high-level (n = 25) group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8524093	The first produced structural protein is the C, a multifunctional protein responsible for packaging viral RNA and drive virion budding process (Hong et al., 2006; Thomas et al., 2010).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Among 285 intensive therapy pts, median OS was 22 months, 34 months in pts without cardiac events (n=125), 43 months with grade 1-2 (n=52), 15 months with grade 3-4 (n=98), and 5.2 months with grade 5 (n=10) (p<0.001).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Data from 90 pts who received mitapivat for >12 mos were pooled from these trials along with pts from the LTE who elected to continue or crossover (if on placebo) to mitapivat.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6461034	Aliquot the beads into as many 1.5‐ml LoBind Eppendorf tubes as there are IPs: “IP” tubes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aliquot", "the", "beads", "into",...
PMC9429973	Kaplan Meier curves were performed for PFS & OS, student t and chi squared tests were performed to assess differences between subgroups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Kaplan"...
PMC11604768	d, f Dose-response curves of THRB-1 (d) and Mafb (e) TRE promoters tested in dual-luciferase assays.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "d", ",", "f", ...
PMC11727062	In conclusion, herbal monomers with cold properties may influence melanoma development via several mechanisms, such as regulating the cell cycle, inducing apoptosis, and modulating the tumor microenvironment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11696576	a Comparison between fold change and expression in RNA-Seq libraries from CCRF-CEM cells treated for 16 h with 0.5 μM AVX420 or vehicle control.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "token...
PMC5716223	p < 0.05.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "p", "<", "0.05", "." ] } ]
PMC9844987	These results demonstrate that the promoter sequence and its putative TF binding sites are predictive of the expression variability of a promoter. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These",...
PMC10178190	Secondary antibodies, HRP-linked anti-rabbit (#7074, Cell Signaling Technology), and anti-mouse (NB7539 Novus, Centennial, CO, USA) were used, as per the manufacturers’ instructions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11285179	However, DHRS11 reduces retinoic acid metabolites to related forms of retinol.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "DHRS11", "reduces", "retinoic", "acid", "metabolites", "to", "re...
PMC9429973	Thiamine decreases were uncommon and easily managed with routine monitoring and oral supplementation as needed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thiamine", "decreases", "were", "uncommon", "and", "easily", ...
PMC9429973	At TPO-RA initiation: 9% of p. were on CS and 48% p. had PLAT <30 G/L (median PLAT = 30 G/L), 95 p. (83%) received EPAG and 19 p. (17%) ROMI.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11474209	Hepatocytes, enterocytes, and vital organs, including the lung, heart, spleen, brain, pancreas, and BBB, all involve OATP multi-specific transporters.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7090062	Gastrointestinal stromal tumors (GISTs), the most widespread type of sarcoma, contain driver gene mutations predominantly of receptor tyrosine kinase and platelet-derived growth factor receptor alpha.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11725127	All data were analyzed utilizing GraphPad Prism 5.0, and P < 0.05, P < 0.01, P < 0.001, P < 0.0001 versus control group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11634794	The 10-year overall survival rate of patients with low LAMP1 expression was significantly lower compared to those with high LAMP1 expression ( Figure 3A , P<0.01).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11544122	The next day, 1 L of LB was inoculated with 25 mL of the culture and grown to an OD600 ~0.4–0.6 at 37 °C and then induced with 1 mM IPTG for 3 h at 37 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Based on these results, IBER doses of 1.0, 1.3, and 1.6 mg were chosen for dose optimization of IberDd for RRMM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11367146	These results suggest that VTE effectively inhibited IL-1β induced NF- κβ signalling activation in SW982 human synovial cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ "These", "results", "suggest", "that...
PMC9985266	The expression levels of COL I and COL III gradually increased with increasing induction time, as shown by RT‒qPCR and Western blot results (Additional file 1: Figs. S1C–E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8978939	To this day, more than 500 VHL mutations have been reported according to the Human Gene Mutation Database (HGMD Professional 2020.3, accessed on November 5, 2020).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Future study is warranted to further explore reasons for physician treatment selection.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Future", "study", "is", "warranted", "to", "further", "explore", "reasons", "for...
PMC11629461	The plasmid pcDNA NOX5 (NOX5, AF353088, #69354) was from AddGene (RRID: SCR.002037, Bristol, UK).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11763111	p < 0.05, p < 0.01, p < 0.001, and ***p < 0.0001; ns, not significant On days 14 and 28, the peripheral blood of mice receiving 4KO-LLT1 CAR-T cells contained significantly more CAR-T cells than those treated with 4KO and 1KO CAR-T cells (Fig. 7E), indicating superior expansion of 4KO-LLT1 CAR-T cells compared to...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The Figure shows the Kaplan–Meier survival curves.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "Figure", "shows", "the", "Kaplan", "–", "Meier", "survival", "curves", "." ] } ]
PMC11098378	However, the specific role of SHOC2 in arbovirus restriction requires further investigation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "the", "specific", "role", "of", "SHOC2", "in", "arbov...
PMC11694066	We found that the combination of PARPi and ATRi significantly increased the number of micronuclei in JN1 cells compared with the DMSO control or either of the corresponding monotherapies (Fig. 3G and H).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5443223	Statistical analysis was performed using Microsoft Excel 2010 (Microsoft Corp., Redmond, WA, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "analysis", "was", "performed"...
PMC4839679	Library construction (100 bp, paired-end) and sequencing were carried out by Beijing Genomics Institute (BGI).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Library", "construction", "(...
PMC9429973	Accordingly, after 24 h HexaBody-CD38 induced comparable maximum CDC of CD38 cells in presence or absence of daratumumab.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Accordingly", ",", "after", "24",...
PMC11574029	All experiments were conducted in accordance with the Declaration of Helsinki.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "experiments", "were", "conducted", "in", "accordance", "with", "the", "Declaration",...
PMC4839679	These novel genes include Polybromo-1 (PBRM1), BAP1, SETD2, KDM5C, and KDM6A.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "novel", "genes", "include", "Polybromo-1...
PMC11703992	Additionally, the CD4+ Naive T cells shifted towards CD4+ Memory T cells in both trajectories.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "the", "CD4", "+",...
PMC9780037	Cytochrome b is one of the subunits of coenzyme Q-cyt c reductase (complex III) and cytochrome a is one of the subunits of cyt c oxidase (complex IV) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: The aim of our study was to describe the incidence, treatment and survival of all reported BIA-ALCL cases in the Netherlands.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11745600	These mice could be stably engrafted with hSC-islets, and the mice that received porcine islet grafts promptly exhibited lowered blood glucose levels, maintaining blood glucose levels below the normal glucose range for at least 52 wk posttransplantation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9676986	This huge therapeutic success makes sense, as over-expression of the proteins and mutations in the genes are frequent in patient tissues and related to the proliferation of cancer cells across various cancers (Liu et al., 2020).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9388315	These methyltransferases prevent the activation of MIR317 by hypermethylating this gene region.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "methyltransferases", "prevent", "the", "activation", "of", "MIR317", "by", ...
PMC4443654	Thus substantial levels of variation between cell types are seen for the top ten most influential variables across models (Figure 2B), such that the repressive histone modification H3K9me3 is the only feature, among the ten most influential, shared between all three cell-type models.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: TAPER (NCT03524612), a Phase II, open-label, prospective, single-arm study, aims to determine whether EPAG can induce SRoT in pts with ITP after 1-line CS failure.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11674441	More detailed analyses will be required, such as TCR tetramer analysis or the creation of organoids from tumour samples to perform cytotoxicity assays.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11155445

These ligands show different coordination modes and have diverse applications in biological systems.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "ligands", "show", "different", "coordination", "modes", "and", "ha...

PMC11300639

g–i 786-O cells were transfected with the indicated plasmids or siRNAs for 48 h, or treated with Palbociclib (5 μM) for 24 h. Cells were treated with CHX, and cells were collected for western blotting analysis at different time points.

[ { "tags": [ "B-CellLine", "I-CellLine", "I-CellLine", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11599565

Transdifferentiation” is hence limited to “differentiated” cells, and “metaplasia” comprises both transdifferentiation and switching in to stem cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11727062

Furthermore, β-elemene has been observed to exert no significant impact on the body weight or behavioral patterns of the mice, suggesting an absence of notable systemic toxic side effects (Shi et al. 2015).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11281366

On the other hand, among the 188 genes for which mRNA levels were upregulated, we also identified cellular genes relevant to HIV-1 infection.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC11765988

Neoplastic antigens can trigger a T-helper-mediated hypersensitivity reaction, activating monocytes and forming epithelioid histiocytes .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Neoplastic", "antigens", "can", "trigger", "a", "T-helper-mediate...

PMC5941560

Deletion326108434(0%)(0%)Long Deletion1904118,61060812499125,397(61%)(1.4%)(10%)(1.2%)Long Insertion1039125,91818126,657(31%)(0.25%)(0%)Duplication17,762186315,288(22%)(24%)Inversion149,545183149,715(0.0087%)(7.1%)Intra.

[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "Deletion326108434(0%)(0%)Long", "Deletion1904118,61060812499125,397(61%)(1.4%)(10%)(1.2%)Long", "Insertion1039125,91818126,657(31%)(0.25%)(0%)Duplication17,762186315,288(22%)(24%)Inversion149,545183149,715(0.0087%)(...

PMC11697065

C and D: Correlation of mRNA abundance with protein abundance for LC (C) and HC (D) for all clones.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11754784

Source data are provided as a Source Data file.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Source", "data", "are", "provided", "as", "a", "Source", "Data", "file", "." ] } ]

PMC11697703

M.J.G. is the Stepping Stone Foundation Early Career Professor in Cell and Molecular Biology at Tulane University.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "M.J.G.", "is", "the", "Stepping", "Stone", ...

PMC9429973

No relapses occurred later than 39 mo after discontinuation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "relapses", "occurred", "later", "than", "39", "mo", "after", "discontinuation", "." ] } ]

PMC11621493

All other upregulated species were glycerophospholipids and sphingolipids (supplemental Fig. S8B and C).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "other", "upregulated", "species", "were", "glycerophosphol...

PMC9429973

The addition of venetoclax to established intensive chemotherapy protocols in these trials are generally reported to be associated with enhanced efficacy, frequently at the cost of significant hematological and infectious toxicities that requires dose modifications of both chemotherapy and venetoclax dosing Aims: To as...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9727330

For staining ASNS enzyme, the rabbit monoclonal primary antibody (mAb #92479, Cell Signaling Technology, USA) and goat anti-rabbit IgG (Alexa Fluor 488, Abcam, USA) were used.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11271278

We grouped the loops, called by hichipper, into “normal,” “abnormal cis”, and “trans” groups.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC7553912

Quantitative analysis of the protein expressions of OPN, ANXA1, ANXA2, and TGF-β in the RTECs.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Quantitative", "analysis", "of", "the", ...

PMC11401358

Lingpeng Zhan: Data curation, Formal analysis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lingpeng", "Zhan", ":", "Data", "curation", ",", "Formal", "analysis", "." ] } ]

PMC11686380

Fig. 2The GAP43 p.E111K variant is unstable in vitro and in vivo (A, B) Expression of wild type and GAP43-E111K in COS7 cells (A) or dissociated mouse cortical neurons (B).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11357960

However, local analysis of tumor tissue might be severely limited by the amount of available samples, especially since tissue would be consumed by routine molecular analyses (59).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10882807

P < 0.05, **p < 0.01, ***p < 0.001 Hsa_circ_0005397 affects proliferation in HCC cell lines. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC8041314

We found only 93 reports containing 1049 compounds that qualified for data processing.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "found", "only", "93", "reports", "containing", "1049", "compounds", ...

PMC7338939

Several reports have determined the role for aberrant Notch signaling in melanoma progression and have suggested that its inhibition may provide a valid therapeutic approach (16, 18).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Three patients (12.5%) were 65 years or older.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Three", "patients", "(", "12.5", "%", ")", "were", "65", "years", "or", "older"...

PMC9429973

Aims: This has been a trigger to start a registry for suspected ALPS patients for future genomic characterization.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "This", "has", ...

PMC2944824

JC1 monomers form in apoptotic and unhealthy cells and can measured at an excitation of 485 nm and emission 535 nm.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "JC1", "monomers", ...

PMC11782508

Additionally, conventional PCR confirmed the expression of the azurin gene in the synthesized cDNA.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "conventional", "PCR", "confirmed", "the", ...

PMC11473843

Mutant KRAS: mutKRAS; n = 3. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mutant", "KRAS", ":", "mutKRAS", ";", "n", "=", "3", ".", "(" ] } ]

PMC11453018

For senescence delay experiments, the staining period was shortened to 4 h for non-treated groups showing significant β-Gal positivity.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "senescence", "delay",...

PMC8170755

Real-time polymerase chain reaction (RT-PCR) was used to determine gene expressions using SYBR Green Master Mix (Parstoos, Iran) and ABI Step One Real-Time PCR System (Applied Biosystems, Foster City, CA).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC6461034

In another study, the rhabdomyosarcoma‐derived cell line A204 was associated with PDGFRα signaling (Bai et al, 2012), and INKA scoring of the underlying data accordingly ranks PDGFRα in second place (Fig 4B).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11188874

Positive control indicates E.G7-Ova cells treated with bortezomib at 10 nmol/L for 16 hours.

[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Positive", "control", "indicates", "E.G7-Ova", "cells", "treated", ...

PMC11672881

Gorreja et al. confirmed that ZP4 is regulated by Toll-like receptors and contributes to the immune response, particularly in inflammatory contexts .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Gorreja", "e...

PMC11204465

Compounds 31 and 32 had a significant effect on NO production in their anti-inflammatory activity and a slight inhibitory effect on THF-α and IL-6 expression.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC11521786

Using DU145 and LN-Cap tumor cells as models, it was evident that sera containing anti-HER3 PAbs could also promote the degradation of HER1 and HER2.

[ { "tags": [ "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...

PMC9479186

Figure 1A ) Western blot results showed that, compared with Lv-shCtrl group, the protein levels of NDUFC1 in Lv-shNDUFC1 group were also significantly decreased ( Figure 1B ).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11502327

At the same time, genetic mechanisms such as increased repair of DNA damage, disturbance of intracellular transduction pathways, and changes in cellular genes all act on the OC microenvironment and make the tumor resistant to drugs (23).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11190538

Table 6Anti-proliferative IC50 of C-PC against HepG-2, MCF-7, and HCT-116 cancer cell lines.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ "Table", "6Anti-proliferative", "IC50", "of", ...

PMC10530622

Increased dietary ingestion of oxalate and alterations in intestinal microbiota may further contribute to obesity-associated hyperoxaluria .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Increased", "dietary", "ingestion", "of", "oxalate", "...

PMC5363531

These data indicate that dasatinib sensitizes mesothelioma cells to PEM through TS down-regulation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "data", "indicate", "that", "dasatinib", "sensitizes", "mesothelioma", ...

PMC9429973

A network was constructed that composed RCTs (ALPINE, ELEVATE-RR [NCT02477696], ASCEND [NCT02970318], and MURANO [NCT02005471]).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC9429973

Single versus multiple KIT or RAS mutations also do not seem to have an impact on therapy response.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Single", "versus", "multiple", "KIT", ...

PMC11473843

The normalization was performed with the ΔΔCT method.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "normalization", "was", "performed", "with", "the", "ΔΔCT", "method", "." ] } ]

PMC2196094

Hybridizations were carried out overnight in a solution containing 6× SSC, 3× Denhardts solution, 0.5% SDS, 2 mM EDTA, and 100 μg yeast RNA/ml at 65°C.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC5673060

5420 phosphosites on 1950 proteins were quantified in two or more replicates in the PazR/A204 experiments (Fig. 2A).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "5420", "phosphosites", "on",...

PMC9429973

To further harness their use in patient-derived AML cells, we are exploring and optimizing targeted LNPs for effective siRNA delivery to primary leukaemic cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC9219615

In conclusion, Tpz-1 is a potent and cytotoxic thieno[2,3-c]pyrazole derivative with potent and specific anticancer activity in vitro.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "conclusion", ",", "Tpz-1", ...

PMC5716223

All values are given as the mean ± standard deviation of the mean (SD).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "values", "are", "given", "as", "the", "me...

PMC11544122

The pEC50 was 9.474 for WT and 9.933 GRK KO (in an inverse manner), and the pEC50 was 9.630 for +GRK2/5, 9.665 for +GRK2 (in an inverse manner) and not detected (n.d.)

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11279397

The evaluation of drug similarity is crucial in the production and upgrading of drug entities .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "evaluation", "of", "drug", "similarity", "is", "cruc...

PMC9429973

M. Amatangelo, Y. Cheng, W. Pierceall, N. W. van de Donk, S. Lonial, M. Wang, J. Emerson, K. Hong, P. Maciag, T. Peluso, A. Gandhi, A. Thakurta Bristol Myers Squibb, Princeton, NJ, United States of America; Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Department of Hematology, Cancer Center Amster...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11694066

Cisplatin was used as the positive control.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cisplatin", "was", "used", "as", "the", "positive", "control", "." ] } ]

PMC10523483

Moreover, knockout of H1.2sensitized NSCLC cells to cisplatin, and low H1.2 was associated with longer survival of lung cancer patients who underwent chemotherapy.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC9429973

The mean age for severe COVID-19 was lower in patients with severe SCD (SS/SB0 vs SC/SB+: 23y vs 67.5y) and THAL (major vs intermedia: 43.5 vs 51.3y) (p<0.001).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11732523

Timely antiviral, antifungal, and antibiotic therapies, combined with immunoglobulin replacement and the antifibrotic agent nintedanib, were pivotal in managing infections and immune dysregulation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

CD33 AM exposure, which led to an outgrowth of pAML cells after 12 d, increasing AM concentrations and/or switching the target antigen improved AdCAR-T cell efficacy.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11721587

All quantification data were analyzed by two-tailed Student’s t test.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "quantification", "data", "were", "analyzed", "by", "two-tailed", "Student", "’s", ...

PMC10154097

Henceforth, based on the median circSOX4 expression (Figure 1(a)), 50 HCC patients were assigned into a low- (n = 25) and a high-level (n = 25) group.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8524093

The first produced structural protein is the C, a multifunctional protein responsible for packaging viral RNA and drive virion budding process (Hong et al., 2006; Thomas et al., 2010).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Among 285 intensive therapy pts, median OS was 22 months, 34 months in pts without cardiac events (n=125), 43 months with grade 1-2 (n=52), 15 months with grade 3-4 (n=98), and 5.2 months with grade 5 (n=10) (p<0.001).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Data from 90 pts who received mitapivat for >12 mos were pooled from these trials along with pts from the LTE who elected to continue or crossover (if on placebo) to mitapivat.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC6461034

Aliquot the beads into as many 1.5‐ml LoBind Eppendorf tubes as there are IPs: “IP” tubes.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aliquot", "the", "beads", "into",...

PMC9429973

Kaplan Meier curves were performed for PFS & OS, student t and chi squared tests were performed to assess differences between subgroups.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Kaplan"...

PMC11604768

d, f Dose-response curves of THRB-1 (d) and Mafb (e) TRE promoters tested in dual-luciferase assays.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "d", ",", "f", ...

PMC11727062

In conclusion, herbal monomers with cold properties may influence melanoma development via several mechanisms, such as regulating the cell cycle, inducing apoptosis, and modulating the tumor microenvironment.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11696576

a Comparison between fold change and expression in RNA-Seq libraries from CCRF-CEM cells treated for 16 h with 0.5 μM AVX420 or vehicle control.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "token...

PMC5716223

p < 0.05.

[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "p", "<", "0.05", "." ] } ]

PMC9844987

These results demonstrate that the promoter sequence and its putative TF binding sites are predictive of the expression variability of a promoter. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These",...

PMC10178190

Secondary antibodies, HRP-linked anti-rabbit (#7074, Cell Signaling Technology), and anti-mouse (NB7539 Novus, Centennial, CO, USA) were used, as per the manufacturers’ instructions.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11285179

However, DHRS11 reduces retinoic acid metabolites to related forms of retinol.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "DHRS11", "reduces", "retinoic", "acid", "metabolites", "to", "re...

PMC9429973

Thiamine decreases were uncommon and easily managed with routine monitoring and oral supplementation as needed.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thiamine", "decreases", "were", "uncommon", "and", "easily", ...

PMC9429973

At TPO-RA initiation: 9% of p. were on CS and 48% p. had PLAT <30 G/L (median PLAT = 30 G/L), 95 p. (83%) received EPAG and 19 p. (17%) ROMI.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11474209

Hepatocytes, enterocytes, and vital organs, including the lung, heart, spleen, brain, pancreas, and BBB, all involve OATP multi-specific transporters.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7090062

Gastrointestinal stromal tumors (GISTs), the most widespread type of sarcoma, contain driver gene mutations predominantly of receptor tyrosine kinase and platelet-derived growth factor receptor alpha.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11725127

All data were analyzed utilizing GraphPad Prism 5.0, and P < 0.05, P < 0.01, P < 0.001, P < 0.0001 versus control group.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11634794

The 10-year overall survival rate of patients with low LAMP1 expression was significantly lower compared to those with high LAMP1 expression ( Figure 3A , P<0.01).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11544122

The next day, 1 L of LB was inoculated with 25 mL of the culture and grown to an OD600 ~0.4–0.6 at 37 °C and then induced with 1 mM IPTG for 3 h at 37 °C.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Based on these results, IBER doses of 1.0, 1.3, and 1.6 mg were chosen for dose optimization of IberDd for RRMM.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11367146

These results suggest that VTE effectively inhibited IL-1β induced NF- κβ signalling activation in SW982 human synovial cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ "These", "results", "suggest", "that...

PMC9985266

The expression levels of COL I and COL III gradually increased with increasing induction time, as shown by RT‒qPCR and Western blot results (Additional file 1: Figs. S1C–E).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8978939

To this day, more than 500 VHL mutations have been reported according to the Human Gene Mutation Database (HGMD Professional 2020.3, accessed on November 5, 2020).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Future study is warranted to further explore reasons for physician treatment selection.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Future", "study", "is", "warranted", "to", "further", "explore", "reasons", "for...

PMC11629461

The plasmid pcDNA NOX5 (NOX5, AF353088, #69354) was from AddGene (RRID: SCR.002037, Bristol, UK).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11763111

p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001; ns, not significant On days 14 and 28, the peripheral blood of mice receiving 4KO-LLT1 CAR-T cells contained significantly more CAR-T cells than those treated with 4KO and 1KO CAR-T cells (Fig. 7E), indicating superior expansion of 4KO-LLT1 CAR-T cells compared to...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

The Figure shows the Kaplan–Meier survival curves.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "Figure", "shows", "the", "Kaplan", "–", "Meier", "survival", "curves", "." ] } ]

PMC11098378

However, the specific role of SHOC2 in arbovirus restriction requires further investigation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "the", "specific", "role", "of", "SHOC2", "in", "arbov...

PMC11694066

We found that the combination of PARPi and ATRi significantly increased the number of micronuclei in JN1 cells compared with the DMSO control or either of the corresponding monotherapies (Fig. 3G and H).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC5443223

Statistical analysis was performed using Microsoft Excel 2010 (Microsoft Corp., Redmond, WA, USA).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "analysis", "was", "performed"...

PMC4839679

Library construction (100 bp, paired-end) and sequencing were carried out by Beijing Genomics Institute (BGI).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Library", "construction", "(...

PMC9429973

Accordingly, after 24 h HexaBody-CD38 induced comparable maximum CDC of CD38 cells in presence or absence of daratumumab.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Accordingly", ",", "after", "24",...

PMC11574029

All experiments were conducted in accordance with the Declaration of Helsinki.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "experiments", "were", "conducted", "in", "accordance", "with", "the", "Declaration",...

PMC4839679

These novel genes include Polybromo-1 (PBRM1), BAP1, SETD2, KDM5C, and KDM6A.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "novel", "genes", "include", "Polybromo-1...

PMC11703992

Additionally, the CD4+ Naive T cells shifted towards CD4+ Memory T cells in both trajectories.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "the", "CD4", "+",...

PMC9780037

Cytochrome b is one of the subunits of coenzyme Q-cyt c reductase (complex III) and cytochrome a is one of the subunits of cyt c oxidase (complex IV) .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Aims: The aim of our study was to describe the incidence, treatment and survival of all reported BIA-ALCL cases in the Netherlands.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11745600

These mice could be stably engrafted with hSC-islets, and the mice that received porcine islet grafts promptly exhibited lowered blood glucose levels, maintaining blood glucose levels below the normal glucose range for at least 52 wk posttransplantation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9676986

This huge therapeutic success makes sense, as over-expression of the proteins and mutations in the genes are frequent in patient tissues and related to the proliferation of cancer cells across various cancers (Liu et al., 2020).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9388315

These methyltransferases prevent the activation of MIR317 by hypermethylating this gene region.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "methyltransferases", "prevent", "the", "activation", "of", "MIR317", "by", ...

PMC4443654

Thus substantial levels of variation between cell types are seen for the top ten most influential variables across models (Figure 2B), such that the repressive histone modification H3K9me3 is the only feature, among the ten most influential, shared between all three cell-type models.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Aims: TAPER (NCT03524612), a Phase II, open-label, prospective, single-arm study, aims to determine whether EPAG can induce SRoT in pts with ITP after 1-line CS failure.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11674441

More detailed analyses will be required, such as TCR tetramer analysis or the creation of organoids from tumour samples to perform cytotoxicity assays.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...