PMCID string | Sentences string | ner list |
|---|---|---|
PMC10748106 | The 3D structures of the iridoid glycosides, showing the dipole vector, are displayed in Figure S3. | [
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PMC11661040 | siRNA, lentivirus, and plasmid technologies were applied to modulate gene expression. | [
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PMC8584666 | Therefore, GPI-80 is considered to be a marker for hematopoietic stem cells. | [
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PMC11471157 | This advancement is expected to make substantial contributions to the field of industrial food production. | [
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PMC10998613 | After correlation curves have been fit, initial correlation function amplitudes are used to calculate the fraction of correlated proteins (fc) as shown blow.fc=Gx0maxGG0,GR0, where , , and represent the initial correlation function values for green autocorrelation functions, red autocorrelation functions, and cross-cor... | [
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PMC9429973 | Aims: To characterize second line (2L) treatment patterns and outcomes in patients with R/R MCL initially diagnosed in the rituximab era. | [
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PMC11367146 | Next, the energy minimization process was done with a 10000 steps steepest descent algorithm. | [
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PMC11721064 | The analysis showed that, in addition to the typical expression of Krt10, skin epithelial cells also expressed high levels of stemness-associated genes, whereas corneal epithelial cells exhibited elevated expression of Krt12 (Additional file 1: Fig. S3C). | [
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PMC11402217 | Its antitumor effect is apoptosis-driven, engaging mitochondrial and ER pathways. | [
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PMC8658661 | Thus, a study comparing HepG2 and HepaRG showed that the HB cell line has a greater affinity with normal hepatocytes . | [
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PMC11678448 | In contrast, the levels of the anti-inflammatory cytokine IL-10 were found to be reduced. | [
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PMC5941560 | Instead, they localize to the mitochondria, where they activate a pro-tumorigenic cellular program by regulating mitochondrial transition pore permeability through interaction with cyclophilin D . | [
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PMC11622247 | Fluorogenic hybridization probes are essential tools in modern molecular biology techniques. | [
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PMC10237474 | E-F) Zoom-in spectra of (D) from a deconvoluted mass range of 58600 to 59900 Da shows the full-length protein 4 (E) and 23700–35800 Da shows the clipped species (F). ( | [
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PMC10329237 | Resultant ROS can activate transforming growth factor-β (TGF-β), triggering epithelial-mesenchymal transition (EMT) as the main pathological process in IPF (4). | [
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PMC11301242 | These results suggest that genes involved in ecDNA formation may serve as potential therapeutic targets for patients with ecDNA. | [
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PMC11795610 | Ca-free DMEM medium was obtained from Yuchun biology (Shanghai, China). | [
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PMC11697189 | In order to analyze the prediction effect of signature, ROC curve was constructed and the AUC was computed. | [
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PMC11621493 | Experiments were performed with constructs encoding for active proteins or the catalytically dead mS370A mutant as a control. | [
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PMC11610461 | CTLA4 is associated with regulatory T cells (Pedros et al., 2017). | [
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PMC11615743 | To investigate whether the logic gate device allows the identification of target cells from the cell mixture, CCRF‐CEM cells were first stained with Hoechst at 37 °C for 15 min. | [
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PMC10968586 | In ovarian carcinoma HEY cells, 100 μM OLE was not able to affect cell viability, but acted as an antioxidant, decreasing endogenous and erastin-dependent LIP and ROS levels, preventing erastin-dependent ROS accumulation in mytochondria and increasing glutathione peroxidase 4 (GPX4) levels that were reduced by erastin ... | [
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PMC10523483 | We further examined the correlation between H1C and GCLC, GPX2, or GSTO1 in NSCLC samples. | [
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PMC11714165 | After ten days, D‐luciferin was administered intraperitoneally to each mouse, and the luminescence of the tibia was observed using IVIS. | [
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PMC11413393 | PRMT1 is the canonical member of the type I family responsible for the majority of all aDMA species produced in the cell. | [
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PMC7840816 | Data represent mean ± SD from three independent experiments. * | [
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PMC11549062 | During the previous studies, researches about PTP1B mainly focused on diabetes mellitus, because PTP1B is a negative insulin signaling pathway regulator; hence inhibiting PTP1B increases insulin sensitivity and effectively controls diabetes . | [
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PMC10887351 | The antioxidant role of β3-ARs through the UCP2 protein could control the redox homeostasis in ES cells. | [
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PMC11575040 | In this study, LINC00094 was selected as a metformin-suppressed lncRNA to investigate its specific role in melanoma. | [
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PMC8992508 | Unusually, the substitution of the amide function with the ester one led to derivatives that showed low activities on BCRP (EC50 values between 5.9 and 17 μM). | [
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PMC11687167 | Other studies have indicated a possible association between PCSK9 and T-cell function via several mediators. | [
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PMC10890307 | Accordingly, acidosis allowed the remaining cells to survive for more time, potentially allowing for survival until there is a change in the tumor microenvironment. | [
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PMC6617630 | Targeting MYC in the DHL/THL DLBCLs through bromodomain extra-terminal inhibitors (BETi) (JQ1, I-BET, and OTX015) significantly (p < 0.05) reduced proliferation, similar to WT-MYC cells, accompanied by decreased MYC but not BCL2 protein. | [
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PMC6799808 | Cell viability was assessed with trypan blue exclusion assay, and cell proliferation was evaluated with one-solution assay and by cell enumeration, as previously described. | [
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PMC9429973 | Secondary outcomes included initial DI; relative dose intensity (RDI) (i.e., regular-dose drugs delivered six cycles with just 21 days intervals equals 100%); and incidence of unplanned hospitalization, febrile neutropenia (FN), and treatment-related mortality (TRM). | [
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PMC11545737 | Virulence factors that are involved in the activation or regulation of pyroptosis pathways. * | [
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PMC9429973 | The validation cohort of 103 AML patients was obtained from Xuzhou Central Hospital. | [
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PMC11637276 | Scale bar, 200 μm. | [
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PMC11696576 | The TC20 automated cell counter (BIO-RAD, Hercules, California, USA) was used to count the number of cells and check the viability by staining with trypan blue (0.4%) (NanoEnTek, Waltham, MA, USA). | [
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PMC6487404 | REG have a large number of these characteristics; however our data suggest that REG seems not to be a P-gp substrate. | [
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PMC11064533 | Extracellular appendages and adhesins play a critical role in the specific binding of the bacterial cell to receptors on the host cell (6). | [
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PMC10538569 | In contrast, co-culturing iDCs infected with either HIV-1 Mj4 or Yu-2 and CEMss-CCR5-GPI-scFv X5 resulted in decreasing HIV-1 production. | [
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PMC11718109 | The Andor Dragon Fly 200 (Oxford Instruments) inverted microscope equipped with a Zyla cMOS 5.5 camera and controlled by Fusion (Oxford Instruments) software was used for imaging of COS7 cells. | [
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PMC11697703 | Since Fezf2 is essential for specification of corticospinal projection neurons, but not for specification of callosal projection neurons, we compared this putative regulatory region to the Fezf2 chromatin immunoprecipitation sequencing (ChIP-seq) dataset from Lodato and colleagues obtained from cortical progenitors tra... | [
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PMC11752740 | Notably, in SK-BR3 cells, a fraction affected (Fa) of 0.5 indicates a more favorable synergistic interaction between the two treatments (Fig. 5). | [
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... |
PMC3035438 | We have designed gene knock-in constructs to generate DT40 strains that coexpress chimeric human IgG and chicken IgM via B-cell-specific RNA alternative splicing. | [
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PMC11544122 | The purity and concentration of the proteins were verified by SDS page gel stained with Coomassie blue. | [
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PMC11252553 | As the radiation dose escalates from 4 to 12 Gy, the percentages of apoptotic lymphocytes gradually increase in the irradiated samples at both time points. | [
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PMC11703992 | J The percentage of apoptotic cells in Blank-PMA and DDIT4-OE-PMA induced Jurkat cells, evaluated by flow cytometry analysis with Annexin V-FITC/PI staining (n = 3) Comprehensive exploration of the regulation of DDIT4 on apoptosis of T cells. | [
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PMC11694346 | Thus, their evaluation holds significant promise for proactive healthcare management. | [
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PMC11534035 | Treatment with G36 increased expression of PAI1 and increased migration and colony size in CAL39 cells. | [
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PMC9954564 | The model selection and evaluation follow a similar strategy in the MDR v3.0.2 and GMDR v.0.9 methods. | [
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PMC11323699 | TAX2-Cy5 concentration was calculated as described above. | [
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PMC11335267 | Data represent mean ± SEM. * | [
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PMC11185260 | Log-rank analysis demonstrated a statistically significant difference between the survival curves. | [
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PMC11047729 | A study on the human leukemia cells Hl-60, K562, U937, and THP-1 confirmed direct LAPA-induced cytotoxicity. | [
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PMC11473843 | The expression profile of the genes at the top 5% of standard deviation (SD) revealed a clearcut separation between A549 cells treated with XMD8-92 and Seliciclib and the single treatments or control group (Fig. 4A). | [
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PMC11607764 | The associations between PTBP1 expression level and patient survival. | [
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PMC11592837 | Our results with ETP and DOX point to a much faster DDR in Jurkat cells compared to PBMCs. | [
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PMC11347429 | In addition, exploring whole-blood gene expression provides a valuable avenue for developing clinical tests for point-of-care use, enabling a more personalized and effective approach to patient management. | [
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PMC11574271 | E A diagram illustrating the specific binding site of miR-659-3p within the 3′UTR region of RON mRNA, along with a mutated version of the RON 3′UTR, is presented. | [
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PMC10667689 | Also, G6PD showed increased expression at the transcriptional level in both cell lines compared to the control and PMA group (G, H) (*p < 0.05, **p < 0.01, ***p < 0.001). | [
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PMC11721096 | The methanol extract of A. sparsifolia (83 g) was applied to a silica gel column (100–200 mesh) eluted by dichloromethane–methanol (from 50:1 to 0:1) to afford eight fractions. | [
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PMC11666785 | An additional image is reconstructed from all the single molecules collected in 2-4 consecutive frames. | [
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PMC11687663 | It is noteworthy to mention that, the presence of carbonyl group (C = O, stretching) is supported by the strong absorption peak in the range of 1703 to 1627 cm. | [
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PMC11066331 | 6 Three-dimensional visualization of PCA of 175 mass spectra recorded from 7 binary cell population mixtures (A). | [
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PMC8711270 | Simple retroviruses contain two separate populations of viral RNAs, where viral genomic RNA is distinct from mRNA. | [
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PMC11075223 | Yixue Guangbiji and Mobao Zhaiji Yanfang both mentioned that the prescriptions containing Cimicifugae Rhizoma had the advantage on dysentery and metrorrhagia during the Ming Dynasty . | [
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PMC3681794 | All graphs show the mean absorbance relative to the untreated controls against log drug concentration and are the mean of 3 independent experiments ± SEM. | [
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PMC6600592 | Colorless crystal, yield 89.5%. | [
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PMC11045125 | Of note, the P493-6 cell line expresses much lower levels of some BL-associated (and GC B cell expressed) cellular proteins in comparison to the N1, N3 and N4 stable cell lines derived from the ΔEBNA2 + Myc lymphomas (Fig 8B), including CD10, GCSAM, BACH2, and CD179B (IGLL1). | [
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PMC11659921 | Prognostic models were significantly associated with the immune microenvironment of OV. ( | [
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PMC11682172 | The stimulating effect of T lymphocyte conditioned medium (CM) was grossly similar for all three cell lines and less than the effect of direct T cell contact. | [
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PMC11694625 | Then, the appropriate boxes for the interactions of ligand and receptor were set and the set parameters were saved as conf files. | [
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PMC11301242 | Among them, 6 lncRNAs were found to be amplified in all 23 AML patients with MYC-containing amplicons and in the AML cell line HL60. | [
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PMC8414691 | Scale bar = 10 μm. | [
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PMC11804588 | The authors also developed single-cell FOODIE (scFOODIE) to enable TF footprint analysis in heterogeneous cell populations. | [
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PMC7294030 | Initiator caspases, such as caspase-1, -2, -8, -9, and -10, initiate a proteolytic cascade while activated caspases, such as caspase-3, -6, and -7, are associated with cleavage of specific intracellular substrates (focal adhesion kinase, poly-ADP-ribose polymerase) (Salvesen and Dixit, 1997; Nicholson and Thornberry, 1... | [
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PMC4005030 | It is present in products of plant origin, such as olive oil or white wine . | [
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PMC8345486 | The OVCAR-3 cell line was cultured in high-glucose RPMI 1640 (ATCC modification medium) with 10% FBS and 100 μg/mL penicillin/streptomycin. | [
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PMC10748106 | Geniposide exhibited no activity in these cell lines. | [
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PMC11653533 | F. carica, traditionally used for constipation and respiratory ailments, demonstrates anti-inflammatory and neuroprotective effects, while F. exasperata has shown promising hypoglycemic and hepatoprotective activities, validating its use in traditional medicine for managing blood glucose levels and liver health (Kingsl... | [
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PMC11746948 | g Immunoblot confirmation of APT2 and GPX4 expression in A375 cells with APT2 knockdown, infected with HA-APT2 lentivirus. | [
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PMC11279397 | These analyses provide theoretical support for the antiviral activity of Perilla frutescens and serve as a reference for further research on its pharmacological effects and the development of related drugs. | [
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PMC9429973 | In our study we found a median younger age of the patients at the moment of the diagnostication (median age of 63 years old) compared with the literature and a ratio male:femato 2:1. | [
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PMC8073654 | Phenylbutenoids and curcuminoids have been mainly isolated from Z. cassumunar as a single compound, and its essential oil containing monoterpenoids, sesquiterpenoids, and phenylbutenoids has been assessed primarily for its pharmacological and cosmeceutical use. | [
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PMC6803987 | On P5, the right lobes were fixed with 4% paraformaldehyde and sent to the pathology department of the Affiliated Hospital of Guilin Medical College for pathological section, including paraffin embedding, sectioning, staining (hematoxylin-eosin staining), and observation of pathological changes by optical microscopy. | [
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PMC11486946 | In addition to the detection of EGFR-TKIs, our screening detected non-EGFR-TKI compounds (i.e., broxyquinoline, daunorubicin, eltrombopag, sorafenib, verteporfin, glafenine, and nilotinib), none of which are known to act on EGFR directly. | [
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PMC11216402 | The Mes-like GC cell lines have a higher similarity to fibroblast than the primary tumors, correlations being as high as 0.8. | [
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PMC11529598 | For cell invasion experiments, cells were seeded into the upper chamber of a Boyden chamber coated with Matrigel (BD) at a density of about 2 × 10 cells per well in serum-free DMEM. | [
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"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11085211 | Indeed, the cell line GIST-48b is characterized by the absence of KIT expression, supporting the hypothesis that the mechanism is independent from KIT, possibly paving the way for developing therapeutic strategies other than TKIs in imatinib resistance. | [
{
"tags": [
"O",
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"B-CellLine",
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"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11761919 | The Fiber2-expressing E. faecalis culture without any additives as a control. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"O",
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"tokens": [
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PMC11806182 | MicroRNAs (miRNAs) could provide insights into these mechanisms and reveal potential therapeutic targets. | [
{
"tags": [
"O",
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"O",
"O",
"O",
"O",
"O",
"O",
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"O",
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"tokens": [
"MicroRNAs",
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"could",
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"insigh... |
PMC8469018 | IC50 value for teriflunomide was determined using the AAT Bioquest IC50 calculator. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"IC50",
"value",
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"teriflunomide",
"was",
"determined",
"using",
"the",
"AA... |
PMC11763126 | C KEGG pathway analysis. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"C",
"KEGG",
"pathway",
"analysis",
"."
]
}
] |
PMC11269933 | All data are presented in the form of mean ± SD. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"tokens": [
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"data",
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"presented",
"in",
"the",
"form",
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"mean",
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"SD",... |
PMC8992508 | Acryloylphenylcarboxamide derivatives In the same year, the same research group, reported another series of acryloylphenylcarboxamides [Figure 6] and of acryloylphenylcarboxylates with a 4’-methoxy group on ring A of the chalcone. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
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"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11411131 | FLAG-TrxR1-HA, FLAG-SelN, Tau, FLAG-SelP-HA, and TetR-Sec-Krab were inserted into the multiple cloning site in the pCI-pur vector. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O"
],
"tokens": [
"FLAG-TrxR1-HA",
",",
... |
PMC11707577 | Many viral structures have been used as template for material synthesis and assembly, , including cowpea chlorotic mottle virus (CCMV), , cowpea mosaic virus (CPMV), tobacco mosaic virus (TMV) and M13 bacteriophage. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
PMC11627398 | Xu et al. reported that compared to sepsis patients in the survival group, whole blood copper levels were notably elevated in the death group of sepsis patients , suggesting that high copper levels are associated with the poor prognosis in sepsis patients. | [
{
"tags": [
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
"O",
... |
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