OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11387401	The canonical Wnt signaling pathway has been reported to inhibit HIV transcription and correlates with HIV controller status (Wallace et al, 2020).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC8557138	This indicates a successful vascular organoid model which also requires tailoring metabolic needs and accordingly defined nutrient supply for its longer sustenance and anastomosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11703992	Similarity of CD4+ Memory T cells in GCA and old samples were explored.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Similarity", "of", "CD4", "+", "Memory", "T", "cells", "in", ...
PMC9261184	Only one of the five vent masts (the forward mast, which is common to the vapor main and all cargo tanks) had a flowmeter installed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11591038	It is well understood that the HIF system activates a wide variety of physiological responses to hypoxia, ranging from the enhancement of survival to cell cycle arrest or even cell demise .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8345486	Attenuated total reflectance−Fourier transform infrared (ATR−FTIR) spectroscopy measurements: infrared absorption spectra were recorded using a Smart iTR diamond attenuated total reflectance (ATR) attachment on a Nicolet 6700 FT-IR spectrometer (Thermo Scientific) equipped with an ETC EverGlo* source for the IR range, ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11618052	C NMR (100 MHz, δ ppm CDCl3): 161.82, 159.88, 157.12, 147.70, 140.43, 134.78, 132.82, 130.58, 130.48, 130.41, 130.15, 128.81, 127.51, 126.01, 125.99, 122.23, 120.01, 114.77, 55.65, 27.27, 21.43.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7504302	Encouragingly, all the genes obtained in this analysis have been previously listed as common essential genes , see Table 3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Encouragingly", ",", ...
PMC11015054	Using a microscope camera, 0‐and 24‐h photographs were taken at 100× magnification (Thermo) to evaluate scratch healing.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Using", "a", "mic...
PMC9429973	IL-27 is a member of the IL-12 family of heterodimeric cytokines reported to have pleiotropic functions during cancer development in different malignancies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "IL-27", "is"...
PMC8740518	The median survival time for patients with MM is less than 12 months from onset (Ledda, Senia & Rapisarda, 2018).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10606998	The dose measurements were carried out at the depth corresponding to the middle of the SOBP.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "dose", "measurements", "were", "carried", "out"...
PMC11075223	According to the above structural characteristics, it was speculated that p-hydroxy group of benzene ring might play a therapeutic role .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "According", "to", ...
PMC11171319	Luminal-to-basal transition upon oncogenic stress activation was described , highlighting the epithelial compartment plasticity during tumorigenesis , where differentiated luminal epithelial cells can revert into functional basal stem cells in vivo .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Analysis of the difference between day 37 and day 1 high dose ruxolitinib treated cells revealed 290 peaks differentially enriched.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Analysis", "of", "the", ...
PMC11397654	On the other hand, the diamide derivative containing a 4-(trifluoromethyl)aniline moiety (30c) displayed the highest antiproliferative activity against HeLa cells (IC50 = 18.14 μM, compared to 23.31 μM for 5-FU).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", ...
PMC11409031	Dysfunction or inadequate regulation of T cells within tumors can contribute to resistance against immunotherapy .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Dysfunction", "or", "inadequate", "regulation", "of", "T", ...
PMC11225860	CENP-B analysis showed that there were twice as many chromosomes present with 1µM alisertib in average, with most treated cells showing 46 chromosomal pairs, 4n-aneuploid, compared 23 chromosomal pairs 2n-normalploid with DMSO.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9621239	Spreads were stained with 4′,6-diamidino-2-phenylindole, and metaphase images were captured using a Nikon Eclipse microscope equipped with a CCD camera (Applied Spectral Imaging, Carlsbad, California) and 60× objective lens.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11655536	In further exploration of the mechanism, we found that HA induced an increase of lysosomes, altered their membrane permeability, and increased TFE3 transport into the nucleus to activate lysosomal biogenesis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11721096	Ligand fishing is a promising strategy for the screening of active ingredients from complex natural products.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ligand", "fishing", "is", "a", "promising", "strategy"...
PMC6450504	First, the low molecular weight bPEI used has significantly less cytotoxicity against mammalian cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "First", ",", "the", "low", "molecular", "weight", "bPEI", ...
PMC10975211	Zeng et al. combined the RGD peptide with the selenadiazole derivative (RGD-SeD) for better selectivity and specificity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Zeng", "et", "al.", "combined", ...
PMC11767582	White solid (0.11 g, 0.30 mmol), yield 59%, mp 119–121 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "White", "solid", "(", "0.11", "g", ...
PMC11638255	Vittorio, O. (2024).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Vittorio", ",", "O.", "(", "2024", ")", "." ] } ]
PMC11472639	SMM, smouldering multiple myeloma; GP, generational practitioner.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SMM", ",", "smouldering", "multiple", "myeloma", ";", "GP", ",", "generational", "practitioner",...
PMC10170482	Further, to have more support for our findings, we analyzed MTCO1 gene expression in HCC tissues from an unselected cohort of 12 HCC specimens obtained at the time of tumor resection or biopsy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11545868	This means that, like other isoflavones in particular, it has a chemical structure similar to the hormone estrogen and can exert estrogenic effects in the body .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11549062	Tunnel staining for representative stable plaques and vulnerable carotid plaques. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tunnel", "staining", "for", "representative", "stable", "plaques", "and", "vulnerable", "ca...
PMC11779605	PI78510, ThermoFisher, Waltham, MA, USA), respectively, and homogenized in a 1.5-ml tube using a Bullet Blender Navy Bead Lysis Kit (Cat. #	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11721277	Notably, even at the highest concentration of 1000 nM, no blocking effect was detected.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notably", ",", "even", "at", "the", "highest", "...
PMC11394227	At the same time, the addition of recombinant PDIa4 could refold the antibodies and Fas.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "the", "same", "time", ",", "the", "additio...
PMC6160470	Their potential should be further investigated on in vivo models, while design of novel compounds having MDR-inhibitory activity should comply with molecular characteristics described in our study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11791264	∗∗∗∗p < 0.0001 (Two-way ANOVA followed by Dunnett’s multiple comparison).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "∗∗∗∗p", "<", "0.0001", "(", "Two-way", "ANOVA", "followed", "by", "Du...
PMC10728535	This analysis was carried out on five data sets GSE73935 (GPL13667), GSE51683 (GPL6244), GSE23553 (GPL570), GSE15372 (GPL570), and GSE131978 (GLP96, GPL570) with Affymetrix platforms and one data set, GSE33482 with Agilent‐014850 (GPL6480) platform.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11047729	dose of ATRA, which triggers different outcomes in patients .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "dose", "of", "ATRA", ",", "which", "triggers", "different", "outcomes", "in", "patients", ...
PMC3019555	3D rendering of HIF-1α mRNA and Ago2 further revealed their overlap (Fig. 5 D and Videos 6 and 7).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "3D", "rendering", ...
PMC10411253	Pelvic MRI scanning.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "Pelvic", "MRI", "scanning", "." ] } ]
PMC5363531	Dasatinib at 100 nM inhibited SRC phosphorylation, reduced both TS promoter activity and protein expression; in the sequential mD treatment testing PEM at 100 nM dose a lack of the compensating cell response was observed, with no TS up-regulation and with induction of apoptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Mean total LASA scores increased in the patients receiving PEG treatment for 26 weeks (Table B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mean", "total", "LASA", "scores", "inc...
PMC8973725	A 24-well transwell unit (Corning, New York, USA) with an 8 µm pore size polycarbonate filter was used following the manufacturer’s protocol.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11629143	Transfection used 5 µg DNA in a volume of 100 µL and followed the Xfect protocol (TakaraBio) for 6‐well plates (n = 3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10024132	γ9δ2 T cells can serve as effector cells for blinatumomab action.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "γ9δ2", "T", "cells", "can", "serve", "as", "effector", "cells", "for", "blinatumomab"...
PMC11787355	Blue, Flu TCR-T control cells; purple, PTPRZ1 TCR-T cells in a, c, e–h, j).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Blue", ...
PMC11766174	As expected, the non-TACK compound treatment displayed proportions of CA-positive cells comparable to the vehicle control (Figure 4A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "expected", ...
PMC9243326	The raw sequencing reads of the cDNA libraries were analyzed using the unigene sequencing (Iso-Seq) pipeline supported by Pacific Biosciences (Gordon et al., 2015).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11791432	Huaide Qiu: Visualization, Validation, Supervision, Software.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Huaide", "Qiu", ":", "Visualization", ",", "Validation", ",", "Supervision", ",", "Software", ...
PMC9429973	In the patients with 17p deletion (n=22) or TP53 mutation (n=11), CR and PR were observed in 4 (12.1%) and 29 (87.9%) patients, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Mean RDI was 80.3%, and RDI did not correlate with OS (p=0.32).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mean", "RDI", "was", "80.3", "%", ",", "and", ...
PMC9429973	While mutations of NPM1 are usually considered as a favorable prognostic marker, the vast majority of the patients carry several co-mutations that might influence the prognosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11670407	standard deviation).	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "standard", "deviation", ")", "." ] } ]
PMC11525028	RNA modification has been reported to influence mRNA capping, splicing, export, stability, translation, and many other processes, which play an essential role in tumors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9693627	Unique and razor peptides were used for label-free quantification (LFQ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Unique", "and", "razor", "peptides", "were", "used", "for", "label-free", "quant...
PMC9429973	However, the overall survival (OS) rate after HSCT is reported to be only 20~40%.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "the", "overall", "surv...
PMC11788920	Upon hybridization with the complementary strand, the single-strand is stretched causing separation of the fluorophore and quencher from each other, resulting in emission of a fluorescence signal.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11627398	A total of 2047 DEGs were identified between high- and low-SLC31A1 groups; 2658 DEGs were screened between high- and low-MTF1 groups; 2400 DEGs were screened between high- and low-LIAS groups; 1861 DEGs were screened between high- and low-LIPT1 groups (S3 Table).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6600253	To solve this problem, the use of TIS, which is a senescent response caused by conventional cancer therapy, is suggested as a strategy for overcoming these side effects.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7823217	The developed skin constructs resemble human skin with pronounced stratification of dermis and epidermis and a basement membrane.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "developed", "skin", "constructs", ...
PMC11615101	Graph showing the concentration of α-Taxilin in RA (n=106) compared to OA (n= 96), SLE (n=8), and HC (n=30) patients plasma samples. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3730428	These results indicate that in order for SMCs to unleash the pro-apoptotic potential of TNFα, mesothelioma cells must be cotreated with a FLIP inhibitor.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11317131	Genome engineering by integrases does not rely on host repair and is highly specific for the att sequence that is not present in the unmodified human genome (22).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11411004	We also investigated the effect on HDAC-related isoforms and found that interference with the HDAC5 gene increased the monoclonal antibody titer by 1.64-fold.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", ...
PMC9684669	In addition, we detected an increase in the phosphorylation of CREB1 at S133, although RNA and protein levels remained unchanged ( Figures 5B, C and Figure S5A ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11665584	Keratinocytes comprised most cells in all datasets and were more proliferative in both the PITX1 skin and buccal mucosa (PCNA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Keratinocytes", ...
PMC9429973	Thirty-seven patients transformed during CLL treatment, 56.7% of them were receiving novel agents (Brutons tyrosine kinase inhibitor or BCL2 inhibitor).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11791478	The EC50 was determined using a four-parameter binding model in Prism (GraphPad) based on plots of the median fluorescence intensities of each dilution.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11126803	To further illustrate the influence of LncRNA-SERB on cell metastasis, the transwell Matrigel invasion assays were performed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "further", "illustrate", "the", "...
PMC11754436	C-D) NPEPPS was overexpressed in MG63 OS cells, *Represent comparison with the pN group. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "C-D", ")", "NPEPPS", "was", "...
PMC9019892	We then evaluated the effects of nintedanib on cell cycle progression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "then", "evaluated", "the", "effects", "of", "nintedanib", "on", "cell", "cycle"...
PMC11394112	Sections were cut at 3 μm from the paraffin blocks and mounted onto Superfrost Ultra Plus slides for immunohistochemical staining for human CD20 and counterstained with hematoxylin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10024132	One scFv binds to the pan-B-cell antigen CD19, and the other scFv binds to the ε chain of the T-cell receptor (TCR)/CD3 complex.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11451940	The results suggested that the complexes could interact with DNA via the intercalation mode.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "results", "suggested", "that", "the", "complexes", "could", ...
PMC11301927	Beta-diversity was assessed using the Bray-Curtis and Jaccard dissimilarity measures.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Beta-diversity", "was", "assessed", "using", "the", "Bray-Curtis", "and", "Jaccard", "dissimilarity", ...
PMC9351137	B Mock, left panel; multipolar spindles (MS), middle panel; chromosome misalignments (CM), right panel.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "B", ...
PMC6948907	Furthermore, it has been demonstrated that 5-aza-2´-deoxycytidine combined with histone deacetylase inhibitor sodium phenylbutyrate induce apoptosis in lung tumor cell significantly (Belinsky et al., 2003).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11772449	In vivo experiments confirmed that the combination of Sora and PFD could synergistically inhibit the growth of subcutaneous transplanted tumors in nude mice and significantly reduce the volume (Fig. 7 A, B) and weight (Fig. 7 C) of transplanted tumors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11371747	For FRα we used KB cells (Westerhof et al., 1995b).	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "FRα", "we", "used", "KB", "cells", "(", "Westerhof", ...
PMC6934009	Western blotting was used for the determination of changes in apoptotic protein expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Western", "blotting", "was", "used", "for", "the", "determination", "of", ...
PMC11680982	Totally 2 × 10 cells were equally distributed in 6-well plates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Totally", "2", "×", "10", "cells", "were", "equally", "distributed", "in", "6-well", ...
PMC9596868	No. EN0531) treated sample was used as negative control and lysis buffer was used as no template control.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No.", "EN0531", ")", "treated", ...
PMC9776316	Cisplatin treatment induced the activation of the JNK-cJUN axis, which translocated to the nucleus and drove the transcription of XRCC4 (Figure A3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11632064	Gene set enrichment analyses (GSEA) of normalized reads using the Hallmarks collection of gene sets confirmed the induction of an inflammatory response and the repression of cell cycle genes linked to E2F and checkpoints (Figs 2E and S2C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11583690	This is consistent with the findings by Yongju He et al. (2017) about loading paclitaxel (along with DTX) onto MSN .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10605143	Moreover, even after 21 days of culture, they lacked a hollow lumen (such incomplete luminal development was considered a hallmark of a premalignant state ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10976516	Therefore, ectopic expression of PSGL-1 and SLeX in engineered MSCs does not induce an increased loss of MSCs during passage through the lung capillary vessels but merely causes a more efficient MSC delivery in inflamed tissues.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11676674	Some information on the phytochemical composition of the C. monspeliensis plant is available.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Some", "information", "on", "the", "phytochemical", "composition", "of", "t...
PMC11787355	TCR-T cells generated as described above were resuspended at a concentration of 25 ×10 cells/ml in PBS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TCR-T", "cells", "generated", "as", "described", ...
PMC11519583	Ror2 activates various signaling molecules, including MAPKs [33–35]; therefore, we analyzed the phosphorylation levels of the respective MAPKs in MPs following Wnt5b stimulation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11672142	Human apo-serum transferrin (apo-sTf) was obtained from Sigma (T2036).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Human", "apo-serum", "transferrin", "(", "apo-sTf", ")", "was", "obtained",...
PMC11515150	The normal T cells were used to evaluate the side effects of CAR-NK cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "normal", "T", "cells", "were", "used", "to", "evaluate", ...
PMC11012012	In a cohort of 300 CLL patients, Bologna et al. (2016) observed that the expression of SLAMF1/CD150 (as analyzed by flow cytometry) was lost in a subset of patients with an aggressive CLL that was associated with a shorter time to first treatment and reduced overall survival.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9105697	The exome panel was more effective and sensitive than the breakpoint panel (Figure 4A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "exome", "panel", "was", "more", "effective", ...
PMC10538569	GPI-GFP is enriched on iDCs and co-localization of GPI-GFP and DiD dye on iDCs forming yellow punctae on iDCs were observed ( Figure 7E ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11767582	The more active compounds of this family are analogues with R = H and R = H, Br, OH, or NH2 (Figure 2), displaying cytotoxic activities in the nanomolar range against the K562 leukemia cancer cell line .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11730305	Theoretically, it can be suggested that the induction of oxidative stress by Co3O4@Glu-Ellagic acid NPs can damage the structural and functional parts of the cells, leads to inhibition of cell cycle progression and triggers apoptosis pathways.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11180402	Relative SNHG1 levels in 5637 (SOX2) and 5637 (Vector) cells with 20 µM ISO or 0.1% DMSO were assessed by RT-qPCR. (	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC10006224	b Box plot for the size of gained (406), lost (1029) and shared (2666) loops called at 10-kb resolution between control and NIPBL KD cells (see “Methods” and Supplementary Data 1 for genomic coordinates).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11806106	The partial agonists morphine and buprenorphine were substantially slower in their ability to activate the receptor, with a on rate of app.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC9429973	The data were analyzed with the NCSS® 2020 software.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "data", "were", "analyzed", "with", "the", "NCSS", "®", "2020", "software", "." ...
PMC11401350	Having confirmed neoplastic CD4 + T cell elimination in murine WT splenocytes and AITL biopsies encouraged us to evaluate the mCD8-targeted LVs encoding the anti-CD4CAR expression cassette in vivo in WT C57BL/6 mice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11387401

The canonical Wnt signaling pathway has been reported to inhibit HIV transcription and correlates with HIV controller status (Wallace et al, 2020).

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PMC8557138

This indicates a successful vascular organoid model which also requires tailoring metabolic needs and accordingly defined nutrient supply for its longer sustenance and anastomosis.

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PMC11703992

Similarity of CD4+ Memory T cells in GCA and old samples were explored.

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PMC9261184

Only one of the five vent masts (the forward mast, which is common to the vapor main and all cargo tanks) had a flowmeter installed.

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PMC11591038

It is well understood that the HIF system activates a wide variety of physiological responses to hypoxia, ranging from the enhancement of survival to cell cycle arrest or even cell demise .

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PMC8345486

Attenuated total reflectance−Fourier transform infrared (ATR−FTIR) spectroscopy measurements: infrared absorption spectra were recorded using a Smart iTR diamond attenuated total reflectance (ATR) attachment on a Nicolet 6700 FT-IR spectrometer (Thermo Scientific) equipped with an ETC EverGlo* source for the IR range, ...

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PMC11618052

C NMR (100 MHz, δ ppm CDCl3): 161.82, 159.88, 157.12, 147.70, 140.43, 134.78, 132.82, 130.58, 130.48, 130.41, 130.15, 128.81, 127.51, 126.01, 125.99, 122.23, 120.01, 114.77, 55.65, 27.27, 21.43.

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PMC7504302

Encouragingly, all the genes obtained in this analysis have been previously listed as common essential genes , see Table 3.

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PMC11015054

Using a microscope camera, 0‐and 24‐h photographs were taken at 100× magnification (Thermo) to evaluate scratch healing.

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PMC9429973

IL-27 is a member of the IL-12 family of heterodimeric cytokines reported to have pleiotropic functions during cancer development in different malignancies.

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PMC8740518

The median survival time for patients with MM is less than 12 months from onset (Ledda, Senia & Rapisarda, 2018).

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PMC10606998

The dose measurements were carried out at the depth corresponding to the middle of the SOBP.

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PMC11075223

According to the above structural characteristics, it was speculated that p-hydroxy group of benzene ring might play a therapeutic role .

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PMC11171319

Luminal-to-basal transition upon oncogenic stress activation was described , highlighting the epithelial compartment plasticity during tumorigenesis , where differentiated luminal epithelial cells can revert into functional basal stem cells in vivo .

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PMC9429973

Analysis of the difference between day 37 and day 1 high dose ruxolitinib treated cells revealed 290 peaks differentially enriched.

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PMC11397654

On the other hand, the diamide derivative containing a 4-(trifluoromethyl)aniline moiety (30c) displayed the highest antiproliferative activity against HeLa cells (IC50 = 18.14 μM, compared to 23.31 μM for 5-FU).

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PMC11409031

Dysfunction or inadequate regulation of T cells within tumors can contribute to resistance against immunotherapy .

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PMC11225860

CENP-B analysis showed that there were twice as many chromosomes present with 1µM alisertib in average, with most treated cells showing 46 chromosomal pairs, 4n-aneuploid, compared 23 chromosomal pairs 2n-normalploid with DMSO.

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PMC9621239

Spreads were stained with 4′,6-diamidino-2-phenylindole, and metaphase images were captured using a Nikon Eclipse microscope equipped with a CCD camera (Applied Spectral Imaging, Carlsbad, California) and 60× objective lens.

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PMC11655536

In further exploration of the mechanism, we found that HA induced an increase of lysosomes, altered their membrane permeability, and increased TFE3 transport into the nucleus to activate lysosomal biogenesis.

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PMC11721096

Ligand fishing is a promising strategy for the screening of active ingredients from complex natural products.

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PMC6450504

First, the low molecular weight bPEI used has significantly less cytotoxicity against mammalian cells.

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PMC10975211

Zeng et al. combined the RGD peptide with the selenadiazole derivative (RGD-SeD) for better selectivity and specificity.

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PMC11767582

White solid (0.11 g, 0.30 mmol), yield 59%, mp 119–121 °C.

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PMC11638255

Vittorio, O. (2024).

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PMC11472639

SMM, smouldering multiple myeloma; GP, generational practitioner.

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PMC10170482

Further, to have more support for our findings, we analyzed MTCO1 gene expression in HCC tissues from an unselected cohort of 12 HCC specimens obtained at the time of tumor resection or biopsy.

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PMC11545868

This means that, like other isoflavones in particular, it has a chemical structure similar to the hormone estrogen and can exert estrogenic effects in the body .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11549062

Tunnel staining for representative stable plaques and vulnerable carotid plaques. (

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PMC11779605

PI78510, ThermoFisher, Waltham, MA, USA), respectively, and homogenized in a 1.5-ml tube using a Bullet Blender Navy Bead Lysis Kit (Cat. #

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PMC11721277

Notably, even at the highest concentration of 1000 nM, no blocking effect was detected.

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PMC11394227

At the same time, the addition of recombinant PDIa4 could refold the antibodies and Fas.

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PMC6160470

Their potential should be further investigated on in vivo models, while design of novel compounds having MDR-inhibitory activity should comply with molecular characteristics described in our study.

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PMC11791264

∗∗∗∗p < 0.0001 (Two-way ANOVA followed by Dunnett’s multiple comparison).

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PMC10728535

This analysis was carried out on five data sets GSE73935 (GPL13667), GSE51683 (GPL6244), GSE23553 (GPL570), GSE15372 (GPL570), and GSE131978 (GLP96, GPL570) with Affymetrix platforms and one data set, GSE33482 with Agilent‐014850 (GPL6480) platform.

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PMC11047729

dose of ATRA, which triggers different outcomes in patients .

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PMC3019555

3D rendering of HIF-1α mRNA and Ago2 further revealed their overlap (Fig. 5 D and Videos 6 and 7).

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PMC10411253

Pelvic MRI scanning.

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PMC5363531

Dasatinib at 100 nM inhibited SRC phosphorylation, reduced both TS promoter activity and protein expression; in the sequential mD treatment testing PEM at 100 nM dose a lack of the compensating cell response was observed, with no TS up-regulation and with induction of apoptosis.

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PMC9429973

Mean total LASA scores increased in the patients receiving PEG treatment for 26 weeks (Table B).

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PMC8973725

A 24-well transwell unit (Corning, New York, USA) with an 8 µm pore size polycarbonate filter was used following the manufacturer’s protocol.

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PMC11629143

Transfection used 5 µg DNA in a volume of 100 µL and followed the Xfect protocol (TakaraBio) for 6‐well plates (n = 3).

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PMC10024132

γ9δ2 T cells can serve as effector cells for blinatumomab action.

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PMC11787355

Blue, Flu TCR-T control cells; purple, PTPRZ1 TCR-T cells in a, c, e–h, j).

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PMC11766174

As expected, the non-TACK compound treatment displayed proportions of CA-positive cells comparable to the vehicle control (Figure 4A).

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PMC9243326

The raw sequencing reads of the cDNA libraries were analyzed using the unigene sequencing (Iso-Seq) pipeline supported by Pacific Biosciences (Gordon et al., 2015).

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PMC11791432

Huaide Qiu: Visualization, Validation, Supervision, Software.

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PMC9429973

In the patients with 17p deletion (n=22) or TP53 mutation (n=11), CR and PR were observed in 4 (12.1%) and 29 (87.9%) patients, respectively.

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PMC9429973

Mean RDI was 80.3%, and RDI did not correlate with OS (p=0.32).

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PMC9429973

While mutations of NPM1 are usually considered as a favorable prognostic marker, the vast majority of the patients carry several co-mutations that might influence the prognosis.

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PMC11670407

standard deviation).

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PMC11525028

RNA modification has been reported to influence mRNA capping, splicing, export, stability, translation, and many other processes, which play an essential role in tumors.

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PMC9693627

Unique and razor peptides were used for label-free quantification (LFQ).

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PMC9429973

However, the overall survival (OS) rate after HSCT is reported to be only 20~40%.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "the", "overall", "surv...

PMC11788920

Upon hybridization with the complementary strand, the single-strand is stretched causing separation of the fluorophore and quencher from each other, resulting in emission of a fluorescence signal.

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PMC11627398

A total of 2047 DEGs were identified between high- and low-SLC31A1 groups; 2658 DEGs were screened between high- and low-MTF1 groups; 2400 DEGs were screened between high- and low-LIAS groups; 1861 DEGs were screened between high- and low-LIPT1 groups (S3 Table).

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PMC6600253

To solve this problem, the use of TIS, which is a senescent response caused by conventional cancer therapy, is suggested as a strategy for overcoming these side effects.

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PMC7823217

The developed skin constructs resemble human skin with pronounced stratification of dermis and epidermis and a basement membrane.

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PMC11615101

Graph showing the concentration of α-Taxilin in RA (n=106) compared to OA (n= 96), SLE (n=8), and HC (n=30) patients plasma samples. (

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PMC3730428

These results indicate that in order for SMCs to unleash the pro-apoptotic potential of TNFα, mesothelioma cells must be cotreated with a FLIP inhibitor.

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PMC11317131

Genome engineering by integrases does not rely on host repair and is highly specific for the att sequence that is not present in the unmodified human genome (22).

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PMC11411004

We also investigated the effect on HDAC-related isoforms and found that interference with the HDAC5 gene increased the monoclonal antibody titer by 1.64-fold.

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PMC9684669

In addition, we detected an increase in the phosphorylation of CREB1 at S133, although RNA and protein levels remained unchanged ( Figures 5B, C and Figure S5A ).

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PMC11665584

Keratinocytes comprised most cells in all datasets and were more proliferative in both the PITX1 skin and buccal mucosa (PCNA).

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PMC9429973

Thirty-seven patients transformed during CLL treatment, 56.7% of them were receiving novel agents (Brutons tyrosine kinase inhibitor or BCL2 inhibitor).

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PMC11791478

The EC50 was determined using a four-parameter binding model in Prism (GraphPad) based on plots of the median fluorescence intensities of each dilution.

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PMC11126803

To further illustrate the influence of LncRNA-SERB on cell metastasis, the transwell Matrigel invasion assays were performed.

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PMC11754436

C-D) NPEPPS was overexpressed in MG63 OS cells, *Represent comparison with the pN group. (

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PMC9019892

We then evaluated the effects of nintedanib on cell cycle progression.

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PMC11394112

Sections were cut at 3 μm from the paraffin blocks and mounted onto Superfrost Ultra Plus slides for immunohistochemical staining for human CD20 and counterstained with hematoxylin.

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PMC10024132

One scFv binds to the pan-B-cell antigen CD19, and the other scFv binds to the ε chain of the T-cell receptor (TCR)/CD3 complex.

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PMC11451940

The results suggested that the complexes could interact with DNA via the intercalation mode.

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PMC11301927

Beta-diversity was assessed using the Bray-Curtis and Jaccard dissimilarity measures.

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PMC9351137

B Mock, left panel; multipolar spindles (MS), middle panel; chromosome misalignments (CM), right panel.

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PMC6948907

Furthermore, it has been demonstrated that 5-aza-2´-deoxycytidine combined with histone deacetylase inhibitor sodium phenylbutyrate induce apoptosis in lung tumor cell significantly (Belinsky et al., 2003).

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PMC11772449

In vivo experiments confirmed that the combination of Sora and PFD could synergistically inhibit the growth of subcutaneous transplanted tumors in nude mice and significantly reduce the volume (Fig. 7 A, B) and weight (Fig. 7 C) of transplanted tumors.

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PMC11371747

For FRα we used KB cells (Westerhof et al., 1995b).

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PMC6934009

Western blotting was used for the determination of changes in apoptotic protein expression.

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PMC11680982

Totally 2 × 10 cells were equally distributed in 6-well plates.

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PMC9596868

No. EN0531) treated sample was used as negative control and lysis buffer was used as no template control.

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PMC9776316

Cisplatin treatment induced the activation of the JNK-cJUN axis, which translocated to the nucleus and drove the transcription of XRCC4 (Figure A3).

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PMC11632064

Gene set enrichment analyses (GSEA) of normalized reads using the Hallmarks collection of gene sets confirmed the induction of an inflammatory response and the repression of cell cycle genes linked to E2F and checkpoints (Figs 2E and S2C).

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PMC11583690

This is consistent with the findings by Yongju He et al. (2017) about loading paclitaxel (along with DTX) onto MSN .

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PMC10605143

Moreover, even after 21 days of culture, they lacked a hollow lumen (such incomplete luminal development was considered a hallmark of a premalignant state ).

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PMC10976516

Therefore, ectopic expression of PSGL-1 and SLeX in engineered MSCs does not induce an increased loss of MSCs during passage through the lung capillary vessels but merely causes a more efficient MSC delivery in inflamed tissues.

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PMC11676674

Some information on the phytochemical composition of the C. monspeliensis plant is available.

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PMC11787355

TCR-T cells generated as described above were resuspended at a concentration of 25 ×10 cells/ml in PBS.

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PMC11519583

Ror2 activates various signaling molecules, including MAPKs [33–35]; therefore, we analyzed the phosphorylation levels of the respective MAPKs in MPs following Wnt5b stimulation.

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PMC11672142

Human apo-serum transferrin (apo-sTf) was obtained from Sigma (T2036).

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PMC11515150

The normal T cells were used to evaluate the side effects of CAR-NK cells.

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PMC11012012

In a cohort of 300 CLL patients, Bologna et al. (2016) observed that the expression of SLAMF1/CD150 (as analyzed by flow cytometry) was lost in a subset of patients with an aggressive CLL that was associated with a shorter time to first treatment and reduced overall survival.

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PMC9105697

The exome panel was more effective and sensitive than the breakpoint panel (Figure 4A).

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PMC10538569

GPI-GFP is enriched on iDCs and co-localization of GPI-GFP and DiD dye on iDCs forming yellow punctae on iDCs were observed ( Figure 7E ).

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PMC11767582

The more active compounds of this family are analogues with R = H and R = H, Br, OH, or NH2 (Figure 2), displaying cytotoxic activities in the nanomolar range against the K562 leukemia cancer cell line .

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PMC11730305

Theoretically, it can be suggested that the induction of oxidative stress by Co3O4@Glu-Ellagic acid NPs can damage the structural and functional parts of the cells, leads to inhibition of cell cycle progression and triggers apoptosis pathways.

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PMC11180402

Relative SNHG1 levels in 5637 (SOX2) and 5637 (Vector) cells with 20 µM ISO or 0.1% DMSO were assessed by RT-qPCR. (

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PMC10006224

b Box plot for the size of gained (406), lost (1029) and shared (2666) loops called at 10-kb resolution between control and NIPBL KD cells (see “Methods” and Supplementary Data 1 for genomic coordinates).

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PMC11806106

The partial agonists morphine and buprenorphine were substantially slower in their ability to activate the receptor, with a on rate of app.

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PMC9429973

The data were analyzed with the NCSS® 2020 software.

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PMC11401350

Having confirmed neoplastic CD4 + T cell elimination in murine WT splenocytes and AITL biopsies encouraged us to evaluate the mCD8-targeted LVs encoding the anti-CD4CAR expression cassette in vivo in WT C57BL/6 mice.

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