OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11539788	We showed that RNF19A expression was reduced in BCa tissues and cell lines through data mining of public resources and further experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "showed...
PMC11464982	Several studies have shown that adults respiratorily sensitised to an enzyme are usually able to ingest the corresponding enzyme without acquiring clinical symptoms of food allergy (Armentia et al., 2009; Brisman, 2002; Cullinan et al., 1997; Poulsen, 2004).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9351137	DAPI (blue), anti-α-tubulin (green), tested CRS (red), and merge.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "DAPI", "(", "blue", ")", ",", "a...
PMC11686380	Methylation analysis for CpG dinucleotides within the H19-DMR on chromosome 11p15 and MEST-DMR and PEG10-DMR on chromosome 7 was conducted by pyrosequencing with bisulfite-treated leukocyte genomic DNA sample as described in the manufacturer’s protocol (Qiagen, Valencia, CA, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7868205	The synthesis is performed similarly to the method followed by Song and Kim et al with slight modifications.26 The synthesized nanoparticles were characterized by our previous reports using spectroscopic techniques such as ultraviolet-visible, X-ray photoelectron and fourier-transform infrared spectroscopy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11612794	Cells were cultured with IAA for 12 h and nocodazole was added for last 10 h before immunoprecipitation experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "cultured", "with...
PMC9164404	Specifically, ATP and nicotinic acid adenine dinucleotide were down-regulated and others were up-regulated in the cells treated with Abplatin and cisplatin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Specifically", ...
PMC9429973	Clinical trial information: ChiCTR2200056288.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Clinical", "trial", "information", ":", "ChiCTR2200056288", "." ] } ]
PMC11787355	i PTPRZ1 expression levels in parental and CRISPR PTPRZ1 KO D170_44 cell lines measured with RT-qPCR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "i", "PTPRZ1", "expression", "levels", "in", "parental"...
PMC11116779	Moreover, it is well known that developing analytical methodologies to identify and quantify plastic particles in complex matrices is an urgent need for research concerning quantitative toxicity assessment of plastic pollution.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11525028	Overexpression of ATF4 rescued the decreased protein levels of ASNS induced by NAT10-KO (Figure 4N).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Overexpression", "of", "ATF4", "rescued", "the", ...
PMC9219615	Increased ERK phosphorylation by Tpz-1 could thus potentially disrupt microtubules and lead to mitotic spindle dysfunction.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Increased", "ERK", "phosphorylation", "by", "Tpz-1", "...
PMC11764090	Screening and cultivation of cold-tolerant germplasm resources based on strategies to prevent ice crystals could reveal ways to improve plant growth and defense.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Screeni...
PMC8358006	Gain-of-function mutations leading to the overexpression of PRC2 components or enhancement of the catalytic activity of EZH2 lead to an aberrant increase in global levels of H3K27me3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11655498	Consequently, the approved metabolic regulators could be used to modulate human metabolic pathways, alleviating symptoms associated with EBV-associated diseases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Consequently", ",", ...
PMC11802929	Unsupervised clustering based on peptide amino acid identity and properties resulted in a two-dimensional peptide Uniform Manifold Approximation and Projection (Pep-UMAP) (Fig. 3b, Supplementary Data 4).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11587606	Co-immunoprecipitation (Co-IP) analysis of the interaction between RHBDF1, importin β1 and PKCζ in MCF10A/GFP and MCF10A/RH under 3D cultures (n = 3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Summary/Conclusion: The use of bortezomib triplets in induction varied markedly over time and between selected countries.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Summary/Conclusion", ":", "The", "use", "of", ...
PMC11745823	The stained culture dish was rinsed with water to remove excess dye, the number of colonies formed was counted (clusters containing at least 50 cells are usually considered valid clones), and the clone formation rate was calculated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8777939	Slides were mounted using ProLong Diamond Antifade Mountant with DAPI (Thermo Fisher Scientific, Hillsboro, OR, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Slides", "were", ...
PMC11754432	Modulation of plasma membrane lipids by ALOX15B silencing led to an altered EGFR/STAT1/JAK1 signalling axis, giving insight into how PUFAs may modulate keratinocyte inflammation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10858941	Additionally, two-way ANOVA was used and significance levels were indicated as: #p < 0.05; ##p < 0.01; ###p < 0.001.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11541409	Clearly demonstrates that the non-KIT/PDGFRA mutants are one of the drug resistance mechenisms.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Clearly", "demonstrates", "that", "the", "non-KIT/PDGFRA", "mutants", "are", ...
PMC10237474	Expi293F GnTI showed 1.3x increase in expression titer over CHO-K1, consistent with what we observed for proteins 7, 9 and 10 (compare Figs 4A and 7A, “Expression Titer”; expression gels were shown in S4D Fig).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11661040	D-E) Western blot was used to analyze the expression of CGREF1, β-catenin and Cyclin D in tumor tissues of the two groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11001582	For immunofluorescence, 5-µm sections mounted on glass slides were incubated for 2 h at 60 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "immunofluorescence", ",", "5-µm", ...
PMC11224020	Of note, tissue-resident DCs could not be used for our purpose as they spontaneously upregulate CCR7 expression after tissue disruption.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Of", "note", ",",...
PMC9429973	Nationwide studies have revealed a higher risk of hematological malignancies (HMs) but not colorectal cancer in IBD patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Nationwide", "studies", "hav...
PMC11656380	These results suggest that Tat-Ram13 cell death is nonapoptotic and mediated by rapid plasma membrane rupture.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "results", "suggest", "that", "Tat-Ram13", "ce...
PMC9429973	This results in both agglutination of RBCs and complement-mediated hemolysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "results", "in", "both", "agglutination", "of", "RBCs", "and", "complement-mediated", "he...
PMC11607321	a Cancer cell line multi-omic datasets across the 1523 cancer cell lines.	[ { "tags": [ "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "a", "Cancer", "cell", "line", "multi-omic", "datasets", "across",...
PMC10490530	Further, to bring in a third luciferase in the context of developing a triple luciferase system, a p53-NLuc fusion plasmid construct was used, where modulated NLuc signal was tested to indicate p53 activation and stabilization.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11536589	Each group had four mice.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", "group", "had", "four", "mice", "." ] } ]
PMC9672323	Significant changes are indicated with asterisk (p < 0.05, p < 0.01, p < 0.001, **p < 0.0001).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11788920	Experiments in which the vicinity of PQS was targeted with CRISPR–dCas9 in Burkitt’s lymphoma cells (Ramos cells). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	Results: As of 12/2/21, 27 patients were enrolled, and 26 received axi-cel and ≥1 rituximab dose (15 patients received all 6 rituximab doses); 1 patient discontinued treatment due to an adverse event (AE).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11471176	Error bars represent standard error of the mean for three measurements at each data point.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Error", "bars", "represent", "standard", "error", "of", "th...
PMC6034753	Transcriptional function of Meq is dependent on its dimerization with bZIP proteins such as c-Jun, c-Fos and ATF-3 .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Transcriptional", "function", "of", ...
PMC11713609	I–N) NC, PHLDA2, p53, or p53/PHLDA2 A375 cells were subcutaneously injected into BALB/c nude mice. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ "...
PMC9429973	Acalabrutinib 100 mg was administered orally twice daily until occurrence of progressive disease or unacceptable toxicity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Acalabrutinib", "100", "mg", "was", "administered", "o...
PMC11348300	at 250 mg/kg.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "at", "250", "mg/kg", "." ] } ]
PMC11461833	ns, p > 0.05; , p < 0.05; , p < 0.01; , p < 0.001; **, p < 0.0001.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5443223	Additionally, CEP164 has a key role in primary cilia formation, which is a marker for distal appendages on mature centrioles or basal bodies (3,6).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10988555	GraphPad Software (GraphPad Prism version 8.01 for Windows, GraphPad Software, La Jolla, CA, USA, www.graphpad.com) was used to perform the statistical analysis of the data performing a comparison using one-way ANOVA with a confidence interval of 95%.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3765139	Cell lines were stained with APC-and PE-conjugated monoclonal antibodies against the CD133 and CD117 epitope.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "lines", "were", "stained", "with", "APC-and", "PE-c...
PMC11583010	For α-amanitin coupling, the Fc fragment had amino acid changes L234A and L235A to reduce FcγR binding and amino acid change D265C (ThiomAb) for toxin–linker conjugation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11640247	Furthermore, the weaker interactions of RAC3-R66W with PAK1 and N-WASP may underlie the neurodevelopmental abnormalities observed in this case, as these effectors are involved in critical neuronal processes such as axonal growth, neurite extension, and dendrite formation .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11389534	The modulation of the UFM1 system presents an innovative therapeutic strategy, which could help reduce PD‐1/PD‐L1 expression and, consequently, enhance the ability of the immune system to target and kill tumour cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6617630	WT-MYC (U2932), MYC/BCL2-(LY1), and MYC/BCL2/BCL6 (VAL) DLBCL cell lines were treated with or without suboptimal concentrations of SAHA, I-BET, or their combination for 72 h and analyzed for cell proliferation and survival.	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9318744	Next, we compared the infectivity of ACE2plus and Vero E6 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O" ], "tokens": [ "Next", ",", "we", "compared", "the", "infectivity", "of", "ACE2plus"...
PMC9874064	The schematic illustration of NP-Pt-USP1i-enhanced chemotherapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "schematic", "illustration", "of", "NP-Pt-USP1i-enhanced", "chemotherapy", "." ] } ]
PMC10798140	In comparison to sorafenib, compound 3e exhibited weaker activity against HepG2 cells at 20 μM but higher selectivity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "comparison", "to", ...
PMC9325715	In the characteristic region for stretching vibrations of hydrogen-containing groups (2800–3700 cm) the wide absorption band with a maximum at 3280 cm was assigned to vibrations of O–H and N–H involved in the hydrogen bonds.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11678448	A bar chart was employed to visualize these DEGs (Figure 4C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "bar", "chart", "was", "employed", "to", "visualize", "these", "D...
PMC11519077	Also, BM-MSC caused a higher expression of the NOD1 gene compared to the control group (1.61 ± 0.419; p < 0.01).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10529414	Two micrograms of total RNA quantified using a NanoDrop™ 2000c spectrophotometer (Thermo Fisher Scientific-USA) was used for reverse transcription of messenger RNA using oligo(dT) primers, and cDNA synthesis was performed with a ProtoScript First Strand cDNA synthesis kit (New England Biolabs-USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11575040	The biological roles of LINC00094 and miR-1270 in cell growth, proliferation, cell cycle, apoptosis, and motility were studied using in vitro assays.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11701801	Data are presented as the mean ± SEM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "presented", "as", "the", "mean", "±", "SEM", "." ] } ]
PMC11394227	The transfer solution was then added dropwise to the 6-well plate, gently rolled to mix well, and cultured in a CO2 incubator.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC5811757	Several studies have tried to investigate the relevance of P-gp expression in various tumors osteosarcoma cell lines for example, but the results remain controversial (25, 26).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Therefore, the usage of buccal epithelium swab as the only reference material for the recipient STR profile or for confirming the germinal nature of mutations should be avoided in patients after HSCT.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10747160	Furthermore, we believe it is important to perform more biophysical assessments to verify whether Griffithsin truly has a high affinity for the additional SARS-CoV-2 structural proteins, especially the M protein.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11593713	It is responsible for a wide range of respiratory, gastrointestinal, and ocular infections in humans .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "responsible", "for", "a", "wide...
PMC10587429	Microhematocrit capillary tubes (22-362566, Fisher Scientific, Waltham, MA). -	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Microhematocrit", "capillary", "tubes", "(", "22", "-"...
PMC11733919	It has been reported that the HSP90 inhibitor 17-DMAG, when used at a concentration of 100 nM for 6 and 24 h, may overcome apoptosis resistance in senescent mouse embryonic fibroblasts (MEFs) by decreasing the activity of a pro-survival kinase Akt, a HSP90 client protein.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11335267	Representative images of transverse sections of gastrocnemius muscles from which CSA was determined.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Representative", "images", "of", "transverse", "sections", "of", "gastrocnemius",...
PMC9429973	EASIX was calculated as lactate dehydrogenase (U/I) × Cre (mg/dL) / Plt (nL).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "EASIX", "was", "calculated", "as"...
PMC11419566	But what is certain is that PA causes cancer cells to enter a cell cycle arrest and limits their ability to divide.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "But", "what"...
PMC10723784	The CI values of carboplatin in combination with CBD were 0.36, 0.17, 0.15, and 0.096 following 24, 48, 72, and 96 h contact times, respectively, suggesting a strong synergism in A2780 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9351137	At least 300 telophases were scored in three independent experiments for both treated cells and control HeLa cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "At", "least", "300", "telophases", ...
PMC9429973	Results: Preliminary results were obtained: - Patient 1 had unsuccessful karyotype and JAK2 (p.Val617Phe, VAF 13%) mutation by NGS. -	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11770130	The NTS-NTSR2 signaling controlled the synthesis of ceramides C20–C24, but not C16, by suppressing the phosphorylation of CerS2 via RhoA but not canonical CK2 kinase in white adipocytes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11770199	These data suggested that MSCs were an ideal vehicle to carry p14 protein that could efficiently fuse with neighboring cancer cells and kill them in vitro.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973	Additionally, improvements in FACIT-Fatigue normalization were demonstrated in PADDOCK, PRINCE, and PEGASUS (PEG-to-PEG) patients (Table 1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additio...
PMC2777936	This is in contrast to a recent paper where shRNA-mediated repression of FZD7 decreased POU5F1 expression substantially in human ES cells and moderately in the human EC cell line NCCIT .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11519567	Set the incubator temperature to 40 °C and 42 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Set", "the", "incubator", "temperature", "to", "40", "°", "C", "and", "42"...
PMC11756514	A panel of different soluble and membrane-bound CTLs was generated and characterized ( Figure 1A ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "panel", "of", "different", "soluble", "and", ...
PMC11767725	These interactions ensure a balance between immune tolerance to commensals and activation against invading pathogens.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "interactions", "ensure", "a", "balance", "between", ...
PMC11469524	In human B cells the activation of the key signaling pathway RAF/MEK/ERK by BCR seems to be similar to the activation by receptor tyrosine kinases (Satpathy et al., 2015; Vanshylla et al., 2018) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11607764	In breast cancer, ovarian cancer, colon cancer, clear cell RCC, and UCEC, the total PTBP1 protein level of tumor tissue was significantly increased compared to the normal tissues (Figure 1B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11049548	It is also worth noting that RPMI contains a low level of glucose and no pyruvate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "also", "worth", "noting", "that", "R...
PMC11740207	Very small leukemic-like stem cells (VSLSLCs), positioned at the top of the hierarchical development of the HL60 cell line, may originate from M_VSELSCs, M_HPCs, or LT-LSCs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", ...
PMC11743316	MIEF2, mitochondrial elongation factor 2, which is found in the outer membrane of mitochondria, regulates mitochondrial fission and is overexpressed in ovarian carcinoma.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11604768	BHK-21 cells were maintained in MEM α with GlutaMAX supplemented with 5% FBS, 10% tryptose phosphate broth, penicillin (100 IU/mL) and streptomycin (100 µg/mL) (growth media).	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4443654	These models also allowed us to probe the features underlying regions with variable higher-order structure between cell types, revealing enrichments of cell-type-specific enhancer activity, and suggesting links between functional chromatin states and higher-order domain dynamics.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11687167	A ABCA1 and ABCG1 can regulate intracellular cholesterol efflux.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "ABCA1", "and", "ABCG1", "can", "regulate", "intracellular", "cholesterol", "efflux", "." ] } ]
PMC6643347	Pseudoviruses were obtained according to the previously described method .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Pseudoviruses", "were", "obtained", "according", "to", "the", "previously", "described", "method", "." ...
PMC8540611	This means that it will be more difficult for them to tightly bind with nucleic acids, being fixed on a rigid metal core.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	Newly diagnosed pts with HL Stages I-IV were included.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Newly", "diagnosed", "pts", "with", "HL", "Stages", "I-IV", "were", "included", "." ] } ]
PMC11534035	In contrast, Whitley et al. found that in a study of breast, ovarian, cervical, and endometrial cancer cell lines, various correlations showed cervical and endometrial cell lines were generally less reliant on the PAI1 system for their invasive qualities than breast and ovarian cancer cell lines (11).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11314247	Meanwhile, carcinogenesis and cancer progression are frequently associated with an aberrant state of protein deacetylation by histone deacetylases (HDACs) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Meanwhile", ...
PMC11754436	hFOB1.19 cells were cultured in DMEM/F12 (SH30126.01; HyClone; Cytiva) containing 10% FBS (10099; Thermo Fisher Scientific, Inc.) and 0.3 mg/ml G418 (PB180125; Procell Life Science & Technology Co., Ltd.) with 5% CO2 at 37˚C. The U2-OS, MG63 and 143B OS cell lines were cultured in RPMI 1640 medium (SH30255.01; HyClone;...	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Large sample sizes should reduce this natural variability, but trials involving MDS-patients have thus far been unable to collect more than 38 patients in one study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11518702	The above studies demonstrate that, despite its 21 kDa size, HGAL can dynamically interact via five sets of sub-domains to mediate plasma membrane localization and engage signaling effectors that co-regulate BCR response pathways.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11781181	The degradation of FTH1 releases iron stored in ferritin into the LIP; consequently, the blockade of NCOA4-mediated ferritinophagy notably suppresses ferroptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC11695623	qRT-PCR to detect the knockdown efficiency of DCUN1D5 (B) Effect of down-regulation of DCUN1D5 on cell proliferation ability. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "qRT-PCR", "to", "...
PMC6034753	The kinetics of apoptotic cells at 0, 60, and 90 h are illustrated in Figure 4B.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "kinetics", "of", "apoptotic", "...
PMC11380329	In our experiment, the proliferative activity of OVCAR4 cells treated with P originating from different geographical regions is well manifested by Ki67 immnunofluorescent staining (Fig. 4).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6627640	Testicular germ cell tumors (TGCTs) represent the most common carcinoma of young men between the age of 15–35 .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Testicular", "germ", "cell",...
PMC10976516	The xenogeneic human A549 cell line showed similar carrier efficiency.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "xenogeneic", "human", "A549", "cell", "line", "showed", "similar", "carrier", "e...

PMC11539788

We showed that RNF19A expression was reduced in BCa tissues and cell lines through data mining of public resources and further experiments.

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PMC11464982

Several studies have shown that adults respiratorily sensitised to an enzyme are usually able to ingest the corresponding enzyme without acquiring clinical symptoms of food allergy (Armentia et al., 2009; Brisman, 2002; Cullinan et al., 1997; Poulsen, 2004).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9351137

DAPI (blue), anti-α-tubulin (green), tested CRS (red), and merge.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "DAPI", "(", "blue", ")", ",", "a...

PMC11686380

Methylation analysis for CpG dinucleotides within the H19-DMR on chromosome 11p15 and MEST-DMR and PEG10-DMR on chromosome 7 was conducted by pyrosequencing with bisulfite-treated leukocyte genomic DNA sample as described in the manufacturer’s protocol (Qiagen, Valencia, CA, USA).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7868205

The synthesis is performed similarly to the method followed by Song and Kim et al with slight modifications.26 The synthesized nanoparticles were characterized by our previous reports using spectroscopic techniques such as ultraviolet-visible, X-ray photoelectron and fourier-transform infrared spectroscopy.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11612794

Cells were cultured with IAA for 12 h and nocodazole was added for last 10 h before immunoprecipitation experiments.

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PMC9164404

Specifically, ATP and nicotinic acid adenine dinucleotide were down-regulated and others were up-regulated in the cells treated with Abplatin and cisplatin.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Specifically", ...

PMC9429973

Clinical trial information: ChiCTR2200056288.

[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Clinical", "trial", "information", ":", "ChiCTR2200056288", "." ] } ]

PMC11787355

i PTPRZ1 expression levels in parental and CRISPR PTPRZ1 KO D170_44 cell lines measured with RT-qPCR.

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PMC11116779

Moreover, it is well known that developing analytical methodologies to identify and quantify plastic particles in complex matrices is an urgent need for research concerning quantitative toxicity assessment of plastic pollution.

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PMC11525028

Overexpression of ATF4 rescued the decreased protein levels of ASNS induced by NAT10-KO (Figure 4N).

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PMC9219615

Increased ERK phosphorylation by Tpz-1 could thus potentially disrupt microtubules and lead to mitotic spindle dysfunction.

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PMC11764090

Screening and cultivation of cold-tolerant germplasm resources based on strategies to prevent ice crystals could reveal ways to improve plant growth and defense.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Screeni...

PMC8358006

Gain-of-function mutations leading to the overexpression of PRC2 components or enhancement of the catalytic activity of EZH2 lead to an aberrant increase in global levels of H3K27me3.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11655498

Consequently, the approved metabolic regulators could be used to modulate human metabolic pathways, alleviating symptoms associated with EBV-associated diseases.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Consequently", ",", ...

PMC11802929

Unsupervised clustering based on peptide amino acid identity and properties resulted in a two-dimensional peptide Uniform Manifold Approximation and Projection (Pep-UMAP) (Fig. 3b, Supplementary Data 4).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11587606

Co-immunoprecipitation (Co-IP) analysis of the interaction between RHBDF1, importin β1 and PKCζ in MCF10A/GFP and MCF10A/RH under 3D cultures (n = 3).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Summary/Conclusion: The use of bortezomib triplets in induction varied markedly over time and between selected countries.

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PMC11745823

The stained culture dish was rinsed with water to remove excess dye, the number of colonies formed was counted (clusters containing at least 50 cells are usually considered valid clones), and the clone formation rate was calculated.

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PMC8777939

Slides were mounted using ProLong Diamond Antifade Mountant with DAPI (Thermo Fisher Scientific, Hillsboro, OR, USA).

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PMC11754432

Modulation of plasma membrane lipids by ALOX15B silencing led to an altered EGFR/STAT1/JAK1 signalling axis, giving insight into how PUFAs may modulate keratinocyte inflammation.

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PMC10858941

Additionally, two-way ANOVA was used and significance levels were indicated as: #p < 0.05; ##p < 0.01; ###p < 0.001.

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PMC11541409

Clearly demonstrates that the non-KIT/PDGFRA mutants are one of the drug resistance mechenisms.

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PMC10237474

Expi293F GnTI showed 1.3x increase in expression titer over CHO-K1, consistent with what we observed for proteins 7, 9 and 10 (compare Figs 4A and 7A, “Expression Titer”; expression gels were shown in S4D Fig).

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PMC11661040

D-E) Western blot was used to analyze the expression of CGREF1, β-catenin and Cyclin D in tumor tissues of the two groups.

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PMC11001582

For immunofluorescence, 5-µm sections mounted on glass slides were incubated for 2 h at 60 °C.

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PMC11224020

Of note, tissue-resident DCs could not be used for our purpose as they spontaneously upregulate CCR7 expression after tissue disruption.

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PMC9429973

Nationwide studies have revealed a higher risk of hematological malignancies (HMs) but not colorectal cancer in IBD patients.

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PMC11656380

These results suggest that Tat-Ram13 cell death is nonapoptotic and mediated by rapid plasma membrane rupture.

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PMC9429973

This results in both agglutination of RBCs and complement-mediated hemolysis.

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PMC11607321

a Cancer cell line multi-omic datasets across the 1523 cancer cell lines.

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PMC10490530

Further, to bring in a third luciferase in the context of developing a triple luciferase system, a p53-NLuc fusion plasmid construct was used, where modulated NLuc signal was tested to indicate p53 activation and stabilization.

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PMC11536589

Each group had four mice.

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PMC9672323

Significant changes are indicated with asterisk (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001).

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PMC11788920

Experiments in which the vicinity of PQS was targeted with CRISPR–dCas9 in Burkitt’s lymphoma cells (Ramos cells). (

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PMC9429973

Results: As of 12/2/21, 27 patients were enrolled, and 26 received axi-cel and ≥1 rituximab dose (15 patients received all 6 rituximab doses); 1 patient discontinued treatment due to an adverse event (AE).

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PMC11471176

Error bars represent standard error of the mean for three measurements at each data point.

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PMC6034753

Transcriptional function of Meq is dependent on its dimerization with bZIP proteins such as c-Jun, c-Fos and ATF-3 .

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PMC11713609

I–N) NC, PHLDA2, p53, or p53/PHLDA2 A375 cells were subcutaneously injected into BALB/c nude mice. (

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PMC9429973

Acalabrutinib 100 mg was administered orally twice daily until occurrence of progressive disease or unacceptable toxicity.

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PMC11348300

at 250 mg/kg.

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PMC11461833

ns, p > 0.05; *, p < 0.05; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001.

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PMC5443223

Additionally, CEP164 has a key role in primary cilia formation, which is a marker for distal appendages on mature centrioles or basal bodies (3,6).

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PMC10988555

GraphPad Software (GraphPad Prism version 8.01 for Windows, GraphPad Software, La Jolla, CA, USA, www.graphpad.com) was used to perform the statistical analysis of the data performing a comparison using one-way ANOVA with a confidence interval of 95%.

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PMC3765139

Cell lines were stained with APC-and PE-conjugated monoclonal antibodies against the CD133 and CD117 epitope.

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PMC11583010

For α-amanitin coupling, the Fc fragment had amino acid changes L234A and L235A to reduce FcγR binding and amino acid change D265C (ThiomAb) for toxin–linker conjugation.

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PMC11640247

Furthermore, the weaker interactions of RAC3-R66W with PAK1 and N-WASP may underlie the neurodevelopmental abnormalities observed in this case, as these effectors are involved in critical neuronal processes such as axonal growth, neurite extension, and dendrite formation .

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PMC11389534

The modulation of the UFM1 system presents an innovative therapeutic strategy, which could help reduce PD‐1/PD‐L1 expression and, consequently, enhance the ability of the immune system to target and kill tumour cells.

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PMC6617630

WT-MYC (U2932), MYC/BCL2-(LY1), and MYC/BCL2/BCL6 (VAL) DLBCL cell lines were treated with or without suboptimal concentrations of SAHA, I-BET, or their combination for 72 h and analyzed for cell proliferation and survival.

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PMC9318744

Next, we compared the infectivity of ACE2plus and Vero E6 cells.

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PMC9874064

The schematic illustration of NP-Pt-USP1i-enhanced chemotherapy.

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PMC10798140

In comparison to sorafenib, compound 3e exhibited weaker activity against HepG2 cells at 20 μM but higher selectivity.

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PMC9325715

In the characteristic region for stretching vibrations of hydrogen-containing groups (2800–3700 cm) the wide absorption band with a maximum at 3280 cm was assigned to vibrations of O–H and N–H involved in the hydrogen bonds.

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PMC11678448

A bar chart was employed to visualize these DEGs (Figure 4C).

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PMC11519077

Also, BM-MSC caused a higher expression of the NOD1 gene compared to the control group (1.61 ± 0.419; p < 0.01).

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PMC10529414

Two micrograms of total RNA quantified using a NanoDrop™ 2000c spectrophotometer (Thermo Fisher Scientific-USA) was used for reverse transcription of messenger RNA using oligo(dT) primers, and cDNA synthesis was performed with a ProtoScript First Strand cDNA synthesis kit (New England Biolabs-USA).

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PMC11575040

The biological roles of LINC00094 and miR-1270 in cell growth, proliferation, cell cycle, apoptosis, and motility were studied using in vitro assays.

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PMC11701801

Data are presented as the mean ± SEM.

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PMC11394227

The transfer solution was then added dropwise to the 6-well plate, gently rolled to mix well, and cultured in a CO2 incubator.

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PMC5811757

Several studies have tried to investigate the relevance of P-gp expression in various tumors osteosarcoma cell lines for example, but the results remain controversial (25, 26).

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PMC9429973

Therefore, the usage of buccal epithelium swab as the only reference material for the recipient STR profile or for confirming the germinal nature of mutations should be avoided in patients after HSCT.

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PMC10747160

Furthermore, we believe it is important to perform more biophysical assessments to verify whether Griffithsin truly has a high affinity for the additional SARS-CoV-2 structural proteins, especially the M protein.

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PMC11593713

It is responsible for a wide range of respiratory, gastrointestinal, and ocular infections in humans .

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PMC10587429

Microhematocrit capillary tubes (22-362566, Fisher Scientific, Waltham, MA). -

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PMC11733919

It has been reported that the HSP90 inhibitor 17-DMAG, when used at a concentration of 100 nM for 6 and 24 h, may overcome apoptosis resistance in senescent mouse embryonic fibroblasts (MEFs) by decreasing the activity of a pro-survival kinase Akt, a HSP90 client protein.

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PMC11335267

Representative images of transverse sections of gastrocnemius muscles from which CSA was determined.

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PMC9429973

EASIX was calculated as lactate dehydrogenase (U/I) × Cre (mg/dL) / Plt (nL).

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PMC11419566

But what is certain is that PA causes cancer cells to enter a cell cycle arrest and limits their ability to divide.

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PMC10723784

The CI values of carboplatin in combination with CBD were 0.36, 0.17, 0.15, and 0.096 following 24, 48, 72, and 96 h contact times, respectively, suggesting a strong synergism in A2780 cells.

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PMC9351137

At least 300 telophases were scored in three independent experiments for both treated cells and control HeLa cells.

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PMC9429973

Results: Preliminary results were obtained: - Patient 1 had unsuccessful karyotype and JAK2 (p.Val617Phe, VAF 13%) mutation by NGS. -

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PMC11770130

The NTS-NTSR2 signaling controlled the synthesis of ceramides C20–C24, but not C16, by suppressing the phosphorylation of CerS2 via RhoA but not canonical CK2 kinase in white adipocytes.

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PMC11770199

These data suggested that MSCs were an ideal vehicle to carry p14 protein that could efficiently fuse with neighboring cancer cells and kill them in vitro.

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PMC9429973

Additionally, improvements in FACIT-Fatigue normalization were demonstrated in PADDOCK, PRINCE, and PEGASUS (PEG-to-PEG) patients (Table 1).

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PMC2777936

This is in contrast to a recent paper where shRNA-mediated repression of FZD7 decreased POU5F1 expression substantially in human ES cells and moderately in the human EC cell line NCCIT .

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PMC11519567

Set the incubator temperature to 40 °C and 42 °C.

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PMC11756514

A panel of different soluble and membrane-bound CTLs was generated and characterized ( Figure 1A ).

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PMC11767725

These interactions ensure a balance between immune tolerance to commensals and activation against invading pathogens.

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PMC11469524

In human B cells the activation of the key signaling pathway RAF/MEK/ERK by BCR seems to be similar to the activation by receptor tyrosine kinases (Satpathy et al., 2015; Vanshylla et al., 2018) .

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PMC11607764

In breast cancer, ovarian cancer, colon cancer, clear cell RCC, and UCEC, the total PTBP1 protein level of tumor tissue was significantly increased compared to the normal tissues (Figure 1B).

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PMC11049548

It is also worth noting that RPMI contains a low level of glucose and no pyruvate.

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PMC11740207

Very small leukemic-like stem cells (VSLSLCs), positioned at the top of the hierarchical development of the HL60 cell line, may originate from M_VSELSCs, M_HPCs, or LT-LSCs.

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PMC11743316

MIEF2, mitochondrial elongation factor 2, which is found in the outer membrane of mitochondria, regulates mitochondrial fission and is overexpressed in ovarian carcinoma.

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PMC11604768

BHK-21 cells were maintained in MEM α with GlutaMAX supplemented with 5% FBS, 10% tryptose phosphate broth, penicillin (100 IU/mL) and streptomycin (100 µg/mL) (growth media).

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PMC4443654

These models also allowed us to probe the features underlying regions with variable higher-order structure between cell types, revealing enrichments of cell-type-specific enhancer activity, and suggesting links between functional chromatin states and higher-order domain dynamics.

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PMC11687167

A ABCA1 and ABCG1 can regulate intracellular cholesterol efflux.

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PMC6643347

Pseudoviruses were obtained according to the previously described method .

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PMC8540611

This means that it will be more difficult for them to tightly bind with nucleic acids, being fixed on a rigid metal core.

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PMC9429973

Newly diagnosed pts with HL Stages I-IV were included.

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PMC11534035

In contrast, Whitley et al. found that in a study of breast, ovarian, cervical, and endometrial cancer cell lines, various correlations showed cervical and endometrial cell lines were generally less reliant on the PAI1 system for their invasive qualities than breast and ovarian cancer cell lines (11).

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PMC11314247

Meanwhile, carcinogenesis and cancer progression are frequently associated with an aberrant state of protein deacetylation by histone deacetylases (HDACs) .

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PMC11754436

hFOB1.19 cells were cultured in DMEM/F12 (SH30126.01; HyClone; Cytiva) containing 10% FBS (10099; Thermo Fisher Scientific, Inc.) and 0.3 mg/ml G418 (PB180125; Procell Life Science & Technology Co., Ltd.) with 5% CO2 at 37˚C. The U2-OS, MG63 and 143B OS cell lines were cultured in RPMI 1640 medium (SH30255.01; HyClone;...

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PMC9429973

Large sample sizes should reduce this natural variability, but trials involving MDS-patients have thus far been unable to collect more than 38 patients in one study.

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PMC11518702

The above studies demonstrate that, despite its 21 kDa size, HGAL can dynamically interact via five sets of sub-domains to mediate plasma membrane localization and engage signaling effectors that co-regulate BCR response pathways.

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PMC11781181

The degradation of FTH1 releases iron stored in ferritin into the LIP; consequently, the blockade of NCOA4-mediated ferritinophagy notably suppresses ferroptosis.

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PMC11695623

qRT-PCR to detect the knockdown efficiency of DCUN1D5 (B) Effect of down-regulation of DCUN1D5 on cell proliferation ability. (

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PMC6034753

The kinetics of apoptotic cells at 0, 60, and 90 h are illustrated in Figure 4B.

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PMC11380329

In our experiment, the proliferative activity of OVCAR4 cells treated with P originating from different geographical regions is well manifested by Ki67 immnunofluorescent staining (Fig. 4).

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PMC6627640

Testicular germ cell tumors (TGCTs) represent the most common carcinoma of young men between the age of 15–35 .

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PMC10976516

The xenogeneic human A549 cell line showed similar carrier efficiency.

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